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The Association Between Asymptomatic And Mild Neurocognitive Impairment And Adherence To Antiretroviral Therapy Amongst People Living With Hiv, Violet Maloba Awori

Master of Medicine in Internal Medicine

Background: HIV disease is associated with neurocognitive impairment which is one of the neurological complications of the viral infection. The spectrum of HIV Associated neurocognitive impairment has significantly changed since the advent of ART. The inclusion of the asymptomatic but cognitively impaired population of patients has changed the dynamics of this population, and requires further research to identify the impact it has on the progression of the disease as well as on any other aspects. Poor adherence to ART is one of the main causes of treatment failure and studies done previously point towards the milder forms of Neurocognitive Impairment …

A Survey And Analysis Of The American Public's Perceptions And Knowledge About Antibiotic Resistance, Rebecca R. Carter, Jiayang Sun, Robin L.P. Jump

Faculty Scholarship

Background. Little is known about the American public's perceptions or knowledge about antibiotic-resistant bacteria or antibiotic misuse. We hypothesized that although many people recognize antibiotic resistance as a problem, they may not understand the relationship between antibiotic consumption and selection of resistant bacteria. Methods. We developed and tested a survey asking respondents about their perceptions and knowledge regarding appropriate antibiotic use. Respondents were recruited with the Amazon Mechanical Turk crowdsourcing platform. The survey, carefully designed to assess a crowd-sourced population, asked respondents to explain "antibiotic resistance" in their own words. Subsequent questions were multiple choice. Results. Of 215 respondents, the …

Maternal Inflammatory Markers In The Diagnosis Of Chorioamnionitis And Prediction Of Neonatal Sepsis In Preterm Pre-Labour Rupture Of Membranes: A Systematic Review, Angela Koech Etyang

Master of Medicine in Obstetrics and Gynecology

Background: There is no consensus on the potential role of inflammatory markers in identifying chorioamnionitis in women with Preterm Pre-labour Rupture of Membranes (PPROM) or in predicting Early Onset Neonatal Sepsis (EONS) in their neonates. Objectives: To perform a quantitative review on the accuracy of maternal C reactive protein (CRP), Procalcitonin (PCT) and Interleukin 6 (IL6) in the diagnosis of Histological Chorioamnionitis and/or Funisitis (HCA/Funisitis) and their role in the prediction of EONS in PPROM. Methods: MEDLINE, EMBASE and The Cochrane Library databases were searched from inception to October 2015, for studies where these markers were assessed against a reference …

Cerebral Aspergillosis And Pulmonary Tuberculosis In A Child With Chronic Granulomatous Disease, Muhammad Waqas, Sidra Zafar, Tooba Rehman, Muhammed Riyaz, Muhammad Ehsan Bari, Romana Idress

Section of Neurosurgery

Background: Chronic granulomatous disease (CGD) is an immune disorder that affects phagocytes. It is characterized by recurrent or persistent bacterial and fungal infections. Reports of tuberculosis (TB) in patients with CGD are rare. In developing countries, where TB is endemic, possibility of other chronic infections is often overlooked by physicians.
Case description: We report the case of a 4-year-old boy who had recurrent respiratory infections and episodes of headache. He was put on antituberculosis (ATT) drugs without microbiological or pathological evidence 2 months prior to presentation. The child did not improve and was brought to our hospital where a computed …

Pengembangan Buku Ajar Matakuliah Mikrobiologi Dasar, Mohammad Wildan Habibi, Endang Suarsini, Mohammad Amin

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Microbiology is one of the subjects taken by the students of Biology Education graduate level. The learning process is often used for this just use the presentation and discussion, so that the student obtained just a concept. The purpose of this study is to make products in the form of research-based textbook current that can later be applied to the student. The method used is R & D (Research and Development) ADDIE. The results of this study is the product of the research-based textbook latest that has been validated by subject matter experts (91,25%), instructional media experts (92,85%), and user …

The Frequency Of Influenza And Bacterial Co-Infection: A Systematic Review And Meta-Analysis., Eili Y. Klein, Bradley Monteforte, Alisha Gupta, Wendi Jiang, Larissa May, Yu-Hsiang Hsieh, Andrea Freyer Dugas

Emergency Medicine Faculty Publications

AIM: Co-infecting bacterial pathogens are a major cause of morbidity and mortality in influenza. However, there remains a paucity of literature on the magnitude of co-infection in influenza patients.

METHOD: A systematic search of MeSH, Cochrane Library, Web of Science, SCOPUS, EMBASE, and PubMed was performed. Studies of humans in which all individuals had laboratory confirmed influenza, and all individuals were tested for an array of common bacterial species, met inclusion criteria.

RESULTS: Twenty-seven studies including 3,215 participants met all inclusion criteria. Common etiologies were defined from a subset of eight articles. There was high heterogeneity in the results (I(2) …

170th Commencement Program (2016), College Of The Holy Cross

Commencement Documents

Order of execises for the 170th Commencement of the College of the Holy Cross, held May 27, 2016.

Eleven Faculty Members Named Winners Of The 2016 Dean's Excellence Awards, Kendra Carter

Browse All News

No abstract provided.

2016-May-26-Trained Immunity, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Membrane Insertion For The Detection Of Lipopolysaccharides: Exploring The Dynamics Of Amphiphile-In-Lipid Assays, Loreen R. Stromberg, Nicolas W. Hengartner, Kirstie L. Swingle, Rodney A. Moxley, Steven W. Graves, Gabriel A. Montaño, Harshini Mukundan

School of Veterinary and Biomedical Sciences: Faculty Publications

Shiga toxin-producing Escherichia coli is an important cause of foodborne illness, with cases attributable to beef, fresh produce and other sources. Many serotypes of the pathogen cause disease, and differentiating one serotype from another requires specific identification of the O antigen located on the lipopolysaccharide (LPS) molecule. The amphiphilic structure of LPS poses a challenge when using classical detection methods, which do not take into account its lipoglycan biochemistry. Typically, detection of LPS requires heat or chemical treatment of samples and relies on bioactivity assays for the conserved lipid A portion of the molecule. Our goal was to develop assays …

Current Method Of High Level Disinfection (Hld) Of Duodenoscopes Appears To Prevent Carbapenem-Resistant Enterococcal (Cre) Colonization And Transmission: A Qi Project, Nadia Huq, Melissa Unruh, Brian P. Buggy, Charles Brummitt

Aurora Internal Medicine Residents

Conclusion: HLD appears to eliminate the risk of colonization and transmission of CRE. Periodic cultures of the elevator tip and the scope tip might be a cost effective way to monitor for potential CRE contamination and risk of transmission. Larger data from other centers might be useful to validate the protocol used in this study.

Glycosphingolipid Gm3 Is Indispensable For Dengue Virus Genome Replication, Kezhen Wang, Gang Bian, Tingting Feng, Penghua Wang, Yunsen Li, Jianfeng Dai

NYMC Faculty Publications

Dengue virus (DENV) causes the most prevalent arthropod-borne viral disease of humans worldwide. Glycosphingolipids (GSLs) are involved in virus infection by regulating various steps of viral-host interaction. However, the distinct role of GSLs during DENV infection remains unclear. In this study, we used mouse melanoma B16 cells and their GSL-deficient mutant counterpart GM95 cells to study the influence of GSLs on DENV infection. Surprisingly, GM95 cells were highly resistant to DENV infection compared with B16 cells. Pretreatment of B16 cells with synthetase inhibitor of GM3, the most abundant GSLs in B16 cells, or silencing GM3 synthetase T3GAL5, significantly inhibited DENV …

New Chemical From Antarctic Sponge Extract Kills Mrsa Biofilm, Staff

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No abstract provided.

Germs Know No Color: Racial Segregation In Baltimore During The Influenza Pandemic Of 1918-1919, Victoria L. Michalski

Electronic Theses & Dissertations

The influenza pandemic in 1918-1919 killed more people worldwide in a shorter period than any other known historical epidemic. Wartime conditions and gatherings of large groups of people aided disease transmission. Racial segregation in Baltimore and other cities created overcrowding, and poor living and economic conditions for black citizens. These conditions affected black health and proved conducive to increased viral transmission and subsequent influenza infection. Higher influenza infection rates coupled with lower resistance led to higher mortality rates from secondary complications like pneumonia.

In my work, I examine the pandemic flu in Baltimore and especially racial segregation policies that ultimately …

Data Descriptor: Species Interactions In Occurrence Data For A Community Of Tick-Transmitted Pathogens, Agustín Estrada-Peña, José De La Fuente

Harold W. Manter Laboratory of Parasitology: Library Materials

Interactions between tick species, their realized range of hosts, the pathogens they carry and transmit, and the geographic distribution of species in the Western Palearctic were determined based on evidence published between 1970–2014. These relationships were linked to remotely sensed features of temperature and vegetation and used to extract the network of interactions among the organisms. The resulting datasets focused on niche overlap among ticks and hosts, species interactions, and the fraction of the environmental niche in which tick-borne pathogens may circulate as a result of interactions and overlapping environmental traits. The resulting datasets provide a valuable resource for researchers …

Geodemographic Features Of Human Blastomycosis In Eastern Wisconsin, Dennis J. Baumgardner, Megan E. Huber, Jessica J. F. Kram

Aurora UW Family Medicine Faculty – Milwaukee

Conclusion: Eastern Wisconsin blastomycosis cases were younger, more apt to be male, and were more likely to be near parks/forests/fields. Novel associations of blastomycosis cases with machinery and automobile-related occupations/facilities should be further explored.

Histopathologic Chorioamnionitis: Geodemographic And Clinical Predictors, Jessica J. F. Kram, Dennis J. Baumgardner

Aurora UW Family Medicine Faculty – Milwaukee

Conclusion: A number of pregnancy variables are predictive of HCA [histopathologic chorioamnionitis] in our births, including Milwaukee 532 zip residence. Fever was absent in nearly half of all deliveries with HCA and in a majority of preterm deliveries with HCA. Following birth, clinician suspicion of CA may help guide neonatal antiobiotic use.

Cancer Stem Cell Metabolism., Maria Peiris-Pagès, Ubaldo E. Martinez-Outshoorn, Richard G. Pestell, Federica Sotgia, Michael P Lisanti

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

Cancer is now viewed as a stem cell disease. There is still no consensus on the metabolic characteristics of cancer stem cells, with several studies indicating that they are mainly glycolytic and others pointing instead to mitochondrial metabolism as their principal source of energy. Cancer stem cells also seem to adapt their metabolism to microenvironmental changes by conveniently shifting energy production from one pathway to another, or by acquiring intermediate metabolic phenotypes. Determining the role of cancer stem cell metabolism in carcinogenesis has become a major focus in cancer research, and substantial efforts are conducted towards discovering clinical targets.

Serratia Fonticola, Pathogen Or Bystander? A Case Series And Review Of The Literature, Roberto Viau, Robin L.P. Jump

Faculty Scholarship

Serratia fonticola is an unusual human pathogen, previously described primarily as causing skin and soft tissue infections following trauma. There is little information in the literature about its treatment or susceptibilities. We describe the case of a 67-year-old male with paraplegia who developed urosepsis due to S. fonticola. Blood and urine cultures obtained prior to the initiation of antimicrobials both grew S. fonticola. The patient completed a 15-day course of antimicrobials and had an uneventful recovery.We reviewed 17 other patients with clinical cultures positive for S. fonticola. Of these, 11 isolates were from the genitourinary system, most often as part …

Human Papillomavirus Infection In Rwanda At The Moment Of Implementation Of A National Hpv Vaccination Programme, Fidele Ngabo, Silvia Franceschi, Iacopo Baussano, M. Chantal Umulisa, Peter Snijders, Anne Uyterlinde, Fulvio Lazzarato, Vanessa Tenet, Maurice Gatera, Agnes Binagwaho, Gary Clifford

Dartmouth Scholarship

Cervical cancer is the most common female cancer in Rwanda that, in 2011, became the first African country to implement a national vaccination programme against human papillomavirus (HPV). To provide a robust baseline for future evaluations of vaccine effectiveness, cervical cell specimens were obtained from 2508 women aged 18–69 years from the general population in Kigali, Rwanda, during 2013/14. 20 % of women were HIV-positive. Samples were used for liquid-based cytology and HPV testing (44 types) with GP5+/6+ PC.

James Robert Rawcliffe, Plaintiff And Appellant, V, Robert Anciaux, Et Al., Defendants And Appellees., Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– 2019)

Appeal from the Third District Court, Salt Lake County, State of Utah The Honorable Heather Brereton, District Court No. 140905252

A Multi-Level Model Of Synergistic T Cell Activation, Anna Konstorum, Anthony Vella, Reinhard C. Laubenbacher

Biology and Medicine Through Mathematics Conference

No abstract provided.

Anticipating Elimination Of Mosquito-Borne Diseases, Suzanne M. O'Regan, Jonathan Lillie, John M. Drake

Biology and Medicine Through Mathematics Conference

No abstract provided.

Toward Adaptive Control Of Acute Inflammation, Judy D. Day, Seddik M. Djouadi, Ouassim Bara, Gregory L. Zitelli

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Modeling Of Endotoxin-Induced Inflammation In Young Men, Renee Brady

Biology and Medicine Through Mathematics Conference

No abstract provided.

Mathematical Models Of Hiv And Hpv Coinfection, Samantha Erwin, Meghna Verma, Vida Abedi, Raquel Hontecillas-Magarzo, Stefan Hoops, Josep Bassaganya-Riera, Stanca M. Ciupe

Biology and Medicine Through Mathematics Conference

No abstract provided.

Can Including Time Delay In Epidemic Models Significantly Improve Predictions Concerning Intervention Strategies?, Adrienna N. Bingham, Leah Shaw

Biology and Medicine Through Mathematics Conference

No abstract provided.

Needle In The Haystack: Combining Intravital Imaging And Mathematical Modeling To Understand How Vaccine-Induced T Cells Find Malaria-Infected Cells In Murine Livers, Vitaly V. Ganusov, Ian Cockburn, Reka Kelemen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Improving Hpv Vaccine Series Compliance With Text Message Reminders In Military Women, Alisha J. Keating, Susan Instone, Joseph Burkard

Doctor of Nursing Practice Final Manuscripts

Project Purpose: The purpose of the project was to improve the rate of Human Papillomavirus (HPV) vaccination compliance among military women aged 18-26 years utilizing clinical reminder via text messages.

Background: Specific populations have been particularly effected by low HPV vaccine completion rates including active duty military women. The incidence of high risk sexual behavior in this population is noted to be higher than the general public and sexually transmitted infection (STI) rates are seven times higher in active duty military women compared to the general public. In addition, HPV is the most prevalent STI in this population with an …

Infiltrating Green Into The Urban Machine: Creating Equity Through Zero-Acreage Farms In Nyc, Hania Hribal-Kornilowicz

Student Theses 2015-Present

Urban centers have long been areas characterized by teeming activity, innovation, and idealized opportunity. However, without fail every urban center contains the paradox between abundance and injustice as evidenced by high rates of food insecurity, lack of green space, and the compounding health disparities experienced by predominantly low-income and minority residents. These injustices will only worsen as the impacts of climate change accelerate. In response, this thesis uses New York City as a case study to explore the efficacy of ZFarming, which is farming in and on buildings, for creating more equitable and sustainable cities. This is accomplished by establishing …