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Moment-Type Nonparametric Estimation In Some Direct And Indirect Models, Fairouz M.Ali Elmagbri

Graduate Theses, Dissertations, and Problem Reports (ETD)

In this research, several approximation of the probability density function, cumulative distribution function in some direct and indirect models are proposed. They are based on the knowledge of the moments and the scaled Laplace transform of the target functions. The upper bounds for the uniform rate of approximations as well as the mean squared errors are established. Two cases when the support of underlying function is bounded and unbounded from above are studied. Proposed constructions provide new non-parametric estimates of the distribution and the density functions in right censored, current status, mean residual life time and length biased models. Simulation …

Water Permeability Of New And Maximum Laundered Isolation Gown Cuffs, Stacey Kamarec

Graduate Theses, Dissertations, and Problem Reports (ETD)

ANSI/AAMI PB70 "Liquid barrier performance and classification of protective apparel and drapes intended for use in healthcare facilities" sets barrier performance requirements for the classification of isolation gowns. Manufacturers voluntarily follow these requirements for gowns used in minimal and low risk situations but end users must decide which gown is most suitable for the required task. ANSI/AAMI PB70 classifies isolation gowns based on the level of barrier protection the gowns are expected to provide and recommends several tests to help manufacturers assign the levels to the gowns (1-4). Published literature has identified performance concerns of isolation gowns, but there are …

Schistosoma Mansoni Alkaline Phosphatase Modulate Platelet Derived Sphingosine-1-Phosphate, Manal Elzoheiry, Samar El-Beshbishi, El-Saeed El-Kholy, Manar Azab, Patrick Skelly

Mansoura Medical Journal

Schistosoma mansoni is one of Digenea that infect human causing chronicdebilitating disease, schistomiasis. Although S. mansoni adults are living inthe blood stream (inferior mesenteric venous system), the cut section ofthese vessels with living worms show no obvious immunological (inflammatorycells) or hematological (clot) attack around parasites. It was hypothesizedthat tegumental surface of schistosomes express proteins modulatingthe local environment around them, preventing host defense response.Here we have expressed an active schistosoma tegumental alkaline phosphatase(SmAP) in Chinese hamster ovary (CHO). SmAP is a ~60 kDaecto-nucleotidase metalloenzyme- need divalent ions for fully efficiency atpH 9. . We previously reported that living worms can cleave …

Hospital Preparedness: Effects Of Designated Preparedness Coordinators On Hospital Preparedness For Special Hazard Classes, Rodney Sinelair Jones

Walden Dissertations and Doctoral Studies

Since 9/11, little statistical rigor has been placed on identifying the correlates of hospital preparedness. This quantitative study explores the research question: Is there a correlation between the employment of a designated hospital preparedness coordinator and the reported level of preparedness for: (a) general preparedness; (b) chemical, biological, radiological, and nuclear (CBRN) events; (c) pandemic disease outbreaks; (d) mass casualty events; and (e) internal infrastructure failure, as assessed by an online survey. Alternative analysis was conducted to assess the relationship between access to resources and the 5 dependent variables. Using complexity theory as the theoretical framework, point biserial correlation and …

Incidence Of And Risk Factors For Thromboembolic Events In Elderly Medicare Patients With Kidney Cancer, Monica Kobayashi

Walden Dissertations and Doctoral Studies

The incidence of venous and arterial thromboembolic events (VTEs/ATEs) varies greatly by cancer type and age, with increased risk in the elderly. Very little research has been reported specific to elderly kidney cancer patients. Retrospective cohort analyses of Medicare patients, 11,463 with and 11,463 without kidney cancer, between 2003 and 2010 were conducted to compare incidence rates of VTEs/ATEs in cancer patients with matched noncancer patients and to assess independent risk factors for VTEs in cancer patients. The advanced epidemiology triangle was the theoretical framework used to interpret the association between incident events and other factors. Using Cox proportional hazard …

An Examination Of African American Women With Hiv And Health Care Barriers, Robert Salvatore Petralia

Walden Dissertations and Doctoral Studies

For over 40 years, HIV has been seen as an epidemic and problem on health care that disproportionately affects the African American women (AAW) and population. This epidemic represents 12% of the total U.S. population, yet accounts for 37% of the commutative HIV cases, and 45% of the new HIV cases reported since 1998. Research in this case was needed for increased understanding to this health care problem, between AAW and HIV. A review in the literature indicated the problem and found new alternatives that helped support aspects on today's health care. The purpose of the study was to help …

Best Practices For Controlling Tuberculosis - Training In Correctional Facilities: A Mixed Methods Evaluation, Ellen Reynolds Murray

Walden Dissertations and Doctoral Studies

According to the literature, identifying and treating tuberculosis (TB) in correctional facilities have been problematic for the inmates and also for the communities into which inmates are released. The importance of training those who can identify this disease early into incarceration is vital to halt the transmission. Although some training has been done by public health authorities for corrections, there is little to no evaluation of such training. The aim of this mixed methods retrospective study was to evaluate the effectiveness of a training to control TB in correctional facilities. The Southeastern National Tuberculosis Center (SNTC) conducted 12 trainings between …

Nigerian Cancer Survivors' Perceptions Of Care Received From Health Care Professionals, Olusegun Akinsuli

Walden Dissertations and Doctoral Studies

Cancer patients worldwide receive care from multidisciplinary teams, and patients

sometimes have little or no knowledge about the different treatment options available, making communication with their care providers an important influence in how they perceive their care. Patient satisfaction with care is an important factor in determining survivorship. The increasing prevalence of cancer worldwide has become a huge public health issue. The World Health Organization has warned that the potential gains from combatting infectious diseases in Nigeria might be lost because of the increasing prevalence of cancer. The purpose of this grounded theory study was to obtain the perceptions of …

Vaccination Confidence And Parental Refusal/Delay Of Early Childhood Vaccines, Melissa Gilkey, Annie-Laurie Mcree, Brooke E. Magnus, Paul Reiter, Amanda F. Dempsey, Noel T. Brewer

Psychology Faculty Research and Publications

Objective

To support efforts to address parental hesitancy towards early childhood vaccination, we sought to validate the Vaccination Confidence Scale using data from a large, population-based sample of U.S. parents.

Methods

We used weighted data from 9,354 parents who completed the 2011 National Immunization Survey. Parents reported on the immunization history of a 19- to 35-month-old child in their households. Healthcare providers then verified children’s vaccination status for vaccines including measles, mumps, and rubella (MMR), varicella, and seasonal flu. We used separate multivariable logistic regression models to assess associations between parents’ mean scores on the 8-item Vaccination Confidence Scale and …

The Impact Of Social Determinants On Tuberculosis Incidence Trends In New Jersey, Thomas Larry Brown

Walden Dissertations and Doctoral Studies

Social determinants have impacted disease states. The purpose of this study was to determine the influence of social determinants on the incidence of tuberculosis over a 20-year period for the state of New Jersey to determine interventions that can be developed for the state. The epidemiological triad (host-agent-environment) served as the theoretical foundation for this study. A quantitative series of cross sectional analyses were performed using secondary data from a New Jersey Department of Health database on population tuberculosis incidence for the state. Categorical data analyses were used to describe the data. According to study results, certain social determinants; such …

The Relationship Between Physical Fitness And School Performance In Middle School Girls, Jamie Anne Donnelly

Walden Dissertations and Doctoral Studies

Past research has indicated a significant relationship between physical fitness and standardized test scores; however, the relationship between physical fitness and other aspects of school performance has yet to be empirically examined in a population specifically composed of middle school girls. This study examined several factors that contribute to school success, such as classroom behavior, attendance, and grades, in relation to physical fitness among a group of adolescent girls. It was specifically designed to examine the statistical relationship between physical fitness, as measured by the Fitnessgram, and quantitative data on school performance including grades, standardized test scores, school behavior, and …

Methamphetamine Users And Gender Differences In Their Acceptance Of Long-Term Substance Abuse Treatment Programs, Kevin Garen Stepanyan

Walden Dissertations and Doctoral Studies

Methamphetamine abuse is a problem of public health importance among men and women in the United States. The two genders are affected even though the majority treatment programs are tailored for male alcohol addicts. The gender differences are prevalent in the acceptance of long-term substance abuse treatment programs. The study focuses on gender differences in methamphetamine abuse and whether both male and female addicts benefit from treatment. Respondent's suitability, participant's abuse condition, treatment, and progress questionnaires and interviews are used to collect data from 50 male and 50 female methamphetamine users at the Impact Residential Program in Montreal, Canada. Together, …

The Impact Of The Sentinel Initiative And Faers Surveillance System On Consumer Safety, Sonia Batra

Walden Dissertations and Doctoral Studies

The U.S. Food and Drug Administration (FDA) uses the FDA Adverse Event Reporting System (FAERS) to monitor adverse events resulting from pharmaceutical drug use. However, this system has limitations such as not allowing real-time data collection. To address these limitations, the FDA launched the Sentinel Initiative in 2008. This comparative case study was conducted to describe perceptions of investigating the efficacy of the Sentinel Initiative compared with the FAERS. The study was based on the theory of preemption as it emphasized the need for efficient means for providing unquestionable proof that consumers suffered adverse drug effects. The sample included interivews …

Methicillin-Resistant Staphylococcus Aureus Infections In The Eight Service Planning Areas Of Los Angeles County, Ildiko Roxane Bocskay

Walden Dissertations and Doctoral Studies

Methicillin-resistant staphylococcus aureus (MRSA) has become resistant to antibiotics. The purpose of this quantitative, retrospective cohort study was to examine the relationship between length of hospitalization and invasive MRSA infection rates among different racial and ethnic groups in the 8 service planning areas (SPAs) of Los Angeles County. Cane, O'Connor, and Michie's theoretical domain framework was used. Secondary data from the Healthcare-Associated (HA) Infections Program of the California Department of Public Health were analyzed. For the first research question, a Pearson correlation analysis was conducted to assess the relationships between length of hospitalization and invasive HA-MRSA infection rates and counts. …

Correlates Of Influenza Vaccination Uptake Among Older Adults, Cheryl Hilliman

Walden Dissertations and Doctoral Studies

Seasonal influenza is associated with signiï¬?cant morbidity and mortality among older adults, aged 65 and older. Since vaccination is the single most effective preventive measure against seasonal influenza, clinicians and senior citizen center administrators need a better understanding of the perceptions of older adults concerning the reason for poor influenza vaccine uptake. The purpose of this study was to identify perceived factors that may be associated with poor influenza vaccination uptake among older adults. The health belief model (HBM) guided the study. The research questions examined perceptions predicting the odds of influenza vaccination uptake among older adults. This quantitative cross-sectional …

Breastfeeding Education For Women With Diabetes, Pregnancy-Induced Hypertension And Multiple Gestations, Oluwapelumi Adefunmike Adeboyejo

Walden Dissertations and Doctoral Studies

Breastfeeding is considered a public health concern due to increased maternal/infant mortality and morbidity rates associated with persistent low rates in breastfeeding. Providing early breastfeeding education for women with diabetic, pregnancy-induced hypertension and multiple gestations can result in higher persistence rates and a decrease in maternal and infant mortality and morbidity rates. This quality improvement project provided early prenatal breastfeeding education for women with diabetes, pregnancy-induce hypertension and multiple gestations at a private clinic in Long Beach, Southern California. Evidence-based literature reviews were conducted through CINAHL and Medline (2009-2014). The descriptive study used for the project was made up questionnaires …

Maternal Characteristics And Childhood Immunization Series Completion Rates Among Children 2-Years-Old, Merlene Ramnon

Walden Dissertations and Doctoral Studies

Delays in childhood immunization may have adverse health implications. In the United States, childhood immunization among children who are below 3 years of age continues to be below Healthy People 2020 targets for some vaccines such as DTaP, PCV, HIB, Hep A, Rotavirus, and Hep B birth dose. The purpose of this study was to examine the association between maternal characteristics and childhood immunization series completion rates among children 2 years of age. The social learning theory and self-efficacy theory provided the theoretical foundation for the study. Data from the Florida Department of Health Immunization Surveys were used. ANOVA and …

Influence Of Mothers-In-Law On Infant Feeding Practices Of Mothers Living With Hiv In Rural Cameroon, Kenneth Ngwambokong Muko

Walden Dissertations and Doctoral Studies

Mothers living with HIV (MLHIV) face complex challenges regarding infant feeding practices, which often restrict their ability to adhere to their chosen or medically recommended feeding behaviors. Mothers-in-law (MIL) enjoy significant influence and participate actively in the rearing of grandchildren in Cameroon. However, the extent to which MIL influence infant feeding behaviors of their daughters-in-law have not been studied. The theory of planned behavior (TPB) was used in this phenomenological study to explore how attitudes, subjective norms, and perceived behavioral control influenced infant feeding practices of 9 MLHIV in rural communities of the North West Region of Cameroon. The five …

Synthesis Of Novel Thiazolylpyrazoline Derivatives And Evaluation Of Their Antimicrobial Activities And Cytotoxicities, Aouatef Tabbi, Zafer Asim Kaplancikli, Dahmane Tebbani, Leyla Yurttaş, Zerri̇n Cantürk, Özlem Atli, Merve Baysal, Gülhan Turan Zitouni

Turkish Journal of Chemistry

Several novel thiazolylpyrazoline derivatives were synthesized by reacting substituted 3,5-diaryl-1-thiocarba\-moyl-2-pyrazolines with phenacylbromides. The structures of the synthesized compounds were confirmed by IR, $^{1}$H NMR, $^{13}$C NMR, and MS spectral data. Their antimicrobial activities against Staphylococcus aureus(ATCC-25923), Enterococcus faecalis} (ATCC-29212), Enterococcus faecalis (ATCC-51922), Listeria monocytogenes (ATCC-1911), Klebsiella pneumoniae (ATCC-700603), Pseudomonas aeruginosa (ATCC-27853), Escherichia coli (ATCC-35218), Escherichia coli (ATCC-25922), Candida albicans (ATCC-90028), Candida glabrata (ATCC-90030), Candida krusei (ATCC-6258), and Candida parapsilosis (ATCC-22019) were investigated. The compounds were also studied for their cytotoxic effects using a MTT assay. Compound 7c showed the highest antimicrobial activity, possessing the same potential as chloramphenicol against K. …

Neoliberalism Redux: The Global Health Policy Agenda And The Politics Of Cooptation In Latin America And Beyond, Anne E Birn, Laura Nervi, Carlos Eduardo Siqueira

Gastón Institute Publications

This article explores the neoliberal cooptation of social justice-oriented global health policies over the last three decades, from primary health care and ‘health for all’ to various contemporary so-called ‘health equity’ initiatives, such as Universal Health Coverage and ‘health convergence’. The authors illustrate and contextualize the different periods and approaches with examples from a range of Latin American countries, drawing on diverse political experiences and social struggles in the health arena. The analysis concludes with reflections about the region’s experiences of resisting and challenging the neoliberal health agenda, in spite of domestic and global environments that have constrained these efforts, …

The Contribution Of Marine Aggregate-Associated Bacteria To The Accumulation Of Pathogenic Bacteria In Oysters: An Agent-Based Model, Andrew M. Kramer, J. Evan Ward, Fred C. Dobbs, Melissa L. Pierce

OES Faculty Publications

Bivalves process large volumes of water, leading to their accumulation of bacteria, including potential human pathogens (e.g., vibrios). These bacteria are captured at low efficiencies when freely suspended in the water column, but they also attach to marine aggregates, which are captured with near 100% efficiency. For this reason, and because they are often enriched with heterotrophic bacteria, marine aggregates have been hypothesized to function as important transporters of bacteria into bivalves. The relative contribution of aggregates and unattached bacteria to the accumulation of these cells, however, is unknown. We developed an agent-based model to simulate accumulation of vibrio-type bacteria …

Deans Of Students’ Responsibilities In Campus Crisis Management, Patrice B. Jackson

College of Graduate Studies: Theses & Dissertations

The purpose of this descriptive quantitative study was to discover the responsibilities of the dean of students in managing campus crisis. The literature clearly identifies the dean of students as a member of the crisis management team (Benjamin, 2014; Zdziarski, 2001, 2006, 2016). However, a gap in the literature exists concerning the specific responsibilities of the dean of students in responding to campus crisis.

The five phases of crisis management as defined by PPD-8 are Prevention, Protection, Mitigation, Response, and Recovery (US Department of Homeland Security, 2011). In signing PPD-8, President Obama mandated all state and federal organizations develop comprehensive …

Higher Education In Ecuador: A Reflective Analysis, Crystal Edenfield

Journal of Higher Education & Student Affairs

Over the last decade, many changes have taken place in Ecuador regarding education, specifically higher education. A new president was elected in 2006 and as a result a new constitution was approved in 2008. This new constitution offered educational opportunities to all Ecuadorians. The purpose of this paper is to analyze higher education in Ecuador. It will discuss and react to Ecuador’s demographics as well as the highlights of the country’s higher education system. It will conclude with considering the implications.

Effect Of Mobile Phone Text Messages Reminders On Uptake Of Routine Immunization Among Children In Pakistan- Study Protocol For A Randomized Clinical Trial, Abdul Momin Kazi, Murtaza Ali, Khurram Zubair, Hussain Kalimuddin, Syed Asad Ali

Department of Paediatrics and Child Health

Introduction: Routine Immunization (RI) is considered one of the best public health interventions to decrease child morbidity and mortality. The RI coverage in Pakistan is still well below the desired level, leading to continued polio transmission, large measles outbreaks and thousands of deaths from vaccine-preventable illnesses. Different innovative and cost effective strategies are required to look into for enhancement in vaccination uptake and coverage. We plan to test the effectiveness of reminders to parents/caregivers on cell phones through short messaging system (SMS) in improving vaccine uptake and on-time routine immunization for children in Pakistan.
Methods and Analysis: A parallel-randomized controlled …

China’S New Law On Exploration And Exploitation Of Resources In The International Seabed Area Of 2016, Nengye Liu, Rakhyun Kim

Research Collection Yong Pung How School Of Law

Despite its rich metallic mineral resources on land,1 the People’s Republic of China (China) has been actively exploring for deep seabed minerals in the international seabed area (the Area).2 The legal framework is provided by the United Nations Convention on the Law of the Sea (LOSC).3 China and the Russian Federation are the only States currently sponsoring exploration of all three types of deep seabed mineral deposit in the Area (polymetallic nodules in the Clarion-Clipperton Fracture Zone, seafloor massive sulphides in the South West Indian Ridge, the Central Indian Ridge, and the Mid-Atlantic Ridge, and cobalt-rich ferromanganese crusts in the …

Reduced Leukocyte Infiltration In Absence Of Eosinophils Correlates With Decreased Tissue Damage And Disease Susceptibility In Δdblgata Mice During Murine Neurocysticercosis, P. K. Mishra, Q. Li, L. E. Munoz, Chris A. Mares, E. G. Morris, J. M. Teale, A. E. Cardona

Biology Faculty Publications (Archived)

Neurocysticercosis (NCC) is one of the most common helminth parasitic diseases of the central nervous system (CNS) and the leading cause of acquired epilepsy worldwide. NCC is caused by the presence of the metacestode larvae of the tapeworm Taenia solium within brain tissues. NCC patients exhibit a long asymptomatic phase followed by a phase of symptoms including increased intra-cranial pressure and seizures. While the asymptomatic phase is attributed to the immunosuppressive capabilities of viable T. solium parasites, release of antigens by dying organisms induce strong immune responses and associated symptoms. Previous studies in T. solium-infected pigs have shown that the …

Space-Time Modelling Of Emerging Infectious Diseases: Assessing Leptospirosis Risk In Sri Lanka, Cameron C F Plouffe

Theses and Dissertations (Comprehensive)

In this research, models were developed to analyze leptospirosis incidence in Sri Lanka and its relation to rainfall. Before any leptospirosis risk models were developed, rainfall data were evaluated from an agro-ecological monitoring network for producing maps of total monthly rainfall in Sri Lanka. Four spatial interpolation techniques were compared: inverse distance weighting, thin-plate splines, ordinary kriging, and Bayesian kriging. Error metrics were used to validate interpolations against independent data. Satellite data were used to assess the spatial pattern of rainfall. Results indicated that Bayesian kriging and splines performed best in low and high rainfall, respectively. Rainfall maps generated from …

Factors Influencing Influenza Vaccination Rates Among Rural Ontario Paramedics, Tonya A. Leduc

Theses and Dissertations (Comprehensive)

Introduction. Influenza vaccination rates have traditionally been very low among healthcare workers (HCWs) however; very few studies have examined vaccination rates andmotivators among paramedics.

Objectives. The Health Belief Model (HBM) (Rosenstock,1974) was used as a guideline in this study to better understand the motivators and barriers to flu vaccination among rural Ontario paramedics. This group represents a considerable proportion of the HCW community, yet it has been virtually omitted from previous research.

Methods. Through the use of self-report questionnaires, and using the HBM as a guideline, a graphical representation of the decision-making process regarding flu vaccination was generated. The sample …

Climate Change And Social Work: Our Roles And Barriers To Action, Tina Cumby

Theses and Dissertations (Comprehensive)

This qualitative research project was conducted using a grounded theory research methodology and was approached with the theoretical underpinnings of social constructivism and pragmatism. The purpose of this research was to assess what role, if any, that social workers can play in dealing with environmental issues such as climate change and what barriers, if any, they will likely experience as they engage with these issues. It is important to explore these roles and barriers because social work is a profession that is well equipped to mitigate environmental issues like climate change, yet there is virtually no social work presence in …

Self-Powered Microfluidic Device For Rapid Assay Of Antiplatelet Drugs, Bincy Jose, Peter Mccluskey, Niamh Gilmartin, Martin Somers, Dermot Kenny, Antonio J. Ricco, Nigel Kent, Lourdes Basabe-Desmonts

Articles

We report the development of a microfluidic device for the rapid assay in whole blood of platelet-protein interactions indicative of the efficacy of antiplatelet drugs—e.g., aspirin and Plavix, two of the world’s most widely used drugs—in cardiovascular patients. Because platelet adhesion to surface-confined protein matrices is modulated by fluid shear rates at the blood/protein interface, and because such binding is a better indicator of platelet function than platelet self-aggregation, we designed, fabricated, and characterized the performance of a family of disposable, self-powered microfluidic chips with well-defined flow and interfacial shear rates suitable for small blood volumes (≤ 200 µL). We …