Digital Commons Network^™

Poor Drug Adherence And Lack Of Awareness Of Hypertension Among Hypertensive Stroke Patients In Kampala, Uganda: A Cross Sectional Study Neurology, Martha Sajatovic, Cathy Sila, Michael Degeorgia

Faculty Scholarship

Background: Raised blood pressure (BP) remains an important risk factor for cardiovascular diseases such as stroke. Adherence to therapeutic recommendations especially antihypertensive drugs is important in BP control. The aim of the study was to assess the stroke risk factors and levels of adherence among hypertensive patients with stroke in Kampala Uganda. Methods: In a cross-sectional study we describe 112 hypertensive subjects with stroke from two Kampala city hospitals. A standardized pre-tested questionnaire was used to collect medical history, clinical details, radiological findings and laboratory data. Results: A total of 112 hypertensive subjects with stroke were enrolled between May 2013 …

Self-Disseminating Vaccines For Emerging Infectious Diseases, Aisling A. Murphy, Alec J. Redwood, Michael A. Jarvis

School of Biomedical Sciences

No abstract provided.

Vol. 41, No. 4: Holiday 2016, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

Co-Infection By Chytrid Fungus And Ranaviruses In Wild And Harvested Frogs In The Tropical Andes., Robin W Warne, Brandon Labumbard, Seth Lagrange, Vance T Vredenburg, Alessandro Catenazzi

Publications

While global amphibian declines are associated with the spread of Batrachochytrium dendrobatidis (Bd), undetected concurrent co-infection by other pathogens may be little recognized threats to amphibians. Emerging viruses in the genus Ranavirus (Rv) also cause die-offs of amphibians and other ectotherms, but the extent of their distribution globally, or how co-infections with Bd impact amphibians are poorly understood. We provide the first report of Bd and Rv co-infection in South America, and the first report of Rv infections in the amphibian biodiversity hotspot of the Peruvian Andes, where Bd is associated with extinctions. Using these data, we tested the hypothesis …

"If We Can Prevent Children From Dying Unnecessarily, I Don't See A Downside": An Analysis Of Vaccinations, Children, Parenting And Vulnerability In Parents And Today’S Parent Articles About Childhood Vaccinations, Cory Runstedler

Sociology Major Research Papers

Since the beginning of the twentieth century, children have been presented by the media and perceived by society as increasingly vulnerable. While using the discussion of childhood vaccinations in parenting magazines as a cultural site, this research explores the presentation of vaccinations, children, parenting, and vulnerability. Methodologically, I conducted a content analysis of 44 articles combined from Parents and Today’s Parent that focus on childhood vaccinations. Throughout the articles children were continually presented as vulnerable, and parents were presented as being responsible caretakers. In addition, a shift was noted where parents were expected to become experts themselves about vaccinations, instead …

Of Life And Limb: The Failure Of Florida's Water Quality Criteria To Test For Vibrio Vulnificus In Coastal Waters And The Need For Enhanced Criteria, Regulation, And Notification To Protect Public Health, Felicia Thomas

Student Works

The nefarious duo of warming oceans and rising sea levels has created a menacing yet lesser-known climate change-induced problem: an increase in sea-borne diseases. For most, the biggest concern when diving into the ocean is a possible, though exceedingly rare, shark encounter; however, it is the unexpected, unseen risk of Vibrio vulnificus that poses the greater danger. Part I of this paper discusses Vibrio vulnificus cases along the coasts of Florida, examining both the illnesses that were contracted through exposure of open wounds to seawater and those contracted through the consumption of raw oysters from the Gulf Coast. Part II …

Evidence Of In Vivo Existence Of Borrelia Biofilm In Borrelial Lymphocytomas, Eva Sapi, Kunthavai Balasubramanian, Akhila Poruri, Jasmin S. Maghsoudlou, Kayla Socarras, Venkata Arun Timmaraju, Katherine Filush, Khusali Gupta, Shafiq Shaikh, Priyanka A.S. Theophilus, David F. Luecke, A. Macdonald, Bettina Zelger

Biology and Environmental Science Faculty Publications

Lyme borreliosis, caused by the spirochete Borrelia burgdorferi sensu lato, has grown into a major public health problem. We recently identified a novel morphological form of B. burgdorferi, called biofilm, a structure that is well known to be highly resistant to antibiotics. However, there is no evidence of the existence of Borrelia biofilm in vivo; therefore, the main goal of this study was to determine the presence of Borrelia biofilm in infected human skin tissues. Archived skin biopsy tissues from borrelial lymphocytomas (BL) were reexamined for the presence of B. burgdorferi sensu lato using Borrelia-specific immunohistochemical staining (IHC), fluorescent in …

Trends In Vaccination Rates Amongst Young Children And The Factors Affecting Parent Decisions, Kaitlyn C. Baldridge, Janna Bjoin, Katherine Pool

All Electronic Theses and Dissertations

Problem: Throughout the United States, there has been an increasing trend in the number of parents refusing to vaccinate their children. Studies have shown that since the upward trend of refusal to vaccinate has started, there has been an increase in outbreaks of preventable diseases. In Minnesota, there have been no studies to evaluate how many parents are refusing vaccinations for their children or the reasons why. Purpose: This study will evaluate how many parents with children ages five and under are choosing to vaccinate their children or refusing vaccination, and the reasons behind their choice to vaccinate or not. …

An Analysis Of Immunization Understanding In Undergraduate Students At Bethel University, Jeff Dahlquist, Steven D. Lindblom

All Electronic Theses and Dissertations

This investigation studied the level of understanding of the nature of immunizations and vaccine preventable diseases in undergraduate students at Bethel University. Immunization literature demonstrates a significant lack of understanding in the general population in relation to the nature of vaccine preventable diseases and the immunizations used to counter them. Furthermore, the literature concludes that such a grossly inadequate understanding of the nature of vaccine preventable diseases may precipitate dire epidemiological consequences. This investigation was a pre-experimental design and utilized a short questionnaire administered one time to a sample population of 171 subjects over 18 years of age who were …

Non-Antibiotic Alternatives For Reducing Antepartum Group B Streptococcus Colonization, Rebecca M. Smith

All Electronic Theses and Dissertations

Background: Streptococcus agalactiae (known as Group B strep, or GBS) is a bacterium that resides in the gastrointestinal tract and/or vaginal canal and is typically benign, but during pregnancy and birth it can potentially colonize the neonate, causing early-onset group B streptococcal disease (EOGBSD) of the neonate. The use of antibiotics has reduced the morbidity and mortality associated with neonatal infections, but it is not an entirely effective means of preventing the infections and the development of antibiotic resistance may render antibiotics ineffective for this purpose. Alternative methods of preventing GBS colonization are in use by consumers and out-of-hospital birth …

Brief For Catholics For Choice Et Al. As Amici Curiae Supporting Respondents, Zubik V. Burwell, Leslie C. Griffin

Supreme Court Briefs

No abstract provided.

A Rare Case Report Of Probable Indigotindisulfonate Sodium-Induced Cardiac Arrest, Andrew P. Smith, Catherine A. Millares-Sipin, Henry Cohen, William Lois

Touro College of Pharmacy (New York) Publications and Research

Background: Indigotindisulfonate (Indigo Carmine, American Regent, Shirely, NY) is a blue dye that is commonly used for localizing ureteral orifices during surgery. In general, it is safe and biologically inactive, with the package insert citing only rare idiosyncratic reactions and mild pressor effects in some patients. We report a case of a severe life-threatening anaphylactoid reaction due to indigotindisulfonate following intravenous administration.

Case Report: We describe a case of a 42-year-old female admitted for a total abdominal hysterectomy. Upon arrival to the operating room, her heart rate (HR) was 80/min, blood pressure (BP) was 135/75 mm Hg, and …

Cyclophosphamide For Suspected Primary Angiitis Of The Central Nervous System In A Patient With Human Immunodeficiency Virus: A Case Report, Martha M. Rumore, Samantha Su, Jake Pellinen

Touro College of Pharmacy (New York) Publications and Research

Introduction: Central nervous system (CNS) vasculitis is rare, including in human immunodeficiency virus (HIV), occurring in less than 1% of patients. Systemic vasculitis affecting the CNS is termed secondary CNS vasculitis, whereas primary CNS vasculitis, referred to as primary angiitis of the CNS (PACNS) refers to an extremely rare disease specifically confined to the CNS. Only some cases of PACNS in HIV patients have been reported in literature.

Case Report: We report a case of a 46-year-old female with HIV who developed probable primary CNS vasculitis, which was treated with intravenous cyclophosphamide and glucocorticoids for both induction and …

Graduate Catalog, 2016-2017, Valparaiso University

Graduate Catalogs

No abstract provided.

Cigarette Tax To Fund Healthcare, Tobacco Use Prevention, Research, And Law Enforcement. Initiative Constitutional Amendment And Statute.

Propositions

Increases cigarette tax by $2.00/pack, with equivalent increase on other tobacco products and electronic cigarettes containing nicotine. • Allocates revenues primarily to increase funding for existing healthcare programs; also for tobacco use prevention/control programs, tobacco-related disease research/law enforcement, University of California physician training, dental disease prevention programs, and administration. Excludes these revenues from Proposition 98 education funding calculation requirements. • If tax causes decreased tobacco consumption, transfers tax revenues to offset decreases to existing tobacco-funded programs and sales tax revenues. • Requires biennial audit. • Increased net state revenue of $1 billion to $1.4 billion in 2017–18, with potentially lower …

Adult Films. Condoms. Health Requirements. Initiative Statute.

Propositions

Requires performers in adult films to use condoms during filming of sexual intercourse. • Requires producers of adult films to pay for performer vaccinations, testing, and medical examinations related to sexually transmitted infections. • Requires producers of adult films to obtain state health license, and to post condom requirement at film sites. • Imposes liability on producers for violations, on certain distributors, on performers if they have a financial interest in the film involved, and on talent agents who knowingly refer performers to noncomplying producers. • Permits state, performers, or any state resident to enforce violations. • Likely reduction of …

Older Adults With Elevated Bmi Are At Greater Risk Of Accelerated Knee Osteoarthritis: Data From The Osteoarthritis Initiative, Kyle D. Wallace

Master of Public Health Program Student Publications

Background: Around 35% of adults with osteoarthritis (OA) have knee osteoarthritis (KOA), which generally progresses over several years; however, some individuals experience accelerated KOA (AKOA), a rapid progression to end-stage disease within 48-months. Purpose: To assess baseline differences among those who develop the different types of KOA, and to determine if baseline characteristics and measures can be used to predict an individual’s KOA status (Common KOA or AKOA) 48 months later.

Methods: Cross-sectional analysis of data from the Osteoarthritis Initiative (OAI) was completed. At baseline, 4,769 participants were enrolled. Data from individuals (n = 1,561) free of radiographic KOA (Kellgren-Lawrence …

A Set Of Smart Practices For Public Health Department Accreditation By Public Health Accreditation Board, Veer Raghava Kumar Marthy

Master of Public Health Program Student Publications

Purpose: The purpose of this research is to determine smart practices that could be used by a public health department to have an efficient, productive and successful accreditation by the Public Health Accreditation Board (PHAB).

Methodology: Accreditation coordinators of eight accredited Ohio-based public health departments were interviewed in 2016. A qualitative study was conducted using semi-structured interviews with funneling. Results were generated using a hybrid model of analysis that included a content analysis to make valid inferences from the interview data.

Results: The accreditation coordinators identified a series of smart practices. Six prominent themes that were identified and labeled as …

Phenotyping And Genotyping Of Cyp2c19 Using Comparative Metabolism Of Proguanil In Sickle‐Cell Disease Patients And Healthy Controls In Nigeria, O. E. Adejumo, T. R. Kotila, A. G. Falusi, B. O. Silva, J. N. Nwogu, P. S. Fasinu, C. P. Babalola

Pharmaceutical Sciences

No abstract provided.

Cherokee Traditional Medicine: Natural Products From Nyssa Sylvatica, William N. Setzer

Summer Community of Scholars (RCEU and HCR) Project Proposals

No abstract provided.

2015-2016 President's Report, Mardi Mileham, Laura Davis

Presidential Reports

The Linfield College President's Annual Report is a collection of information about the year in review, including academics, student life and athletics, enrollment, finances, philanthropy, and leadership.

2016-2017 Pediatric Subspecialty Trainees And Residents, Children's Mercy Hospital

Residents and Fellows Portraits

Photo composites of the graduate pediatric trainees in allergy/immunology, child abuse pediatrics, child neurology, clinical child psychology, clinical cytogenetics & molecular genetics, clinical pharmacology, developmental-behavioral pediatrics, hospice Y palliative care, neonatal-perinatal medicine, pediatric cardiology, pediatric critical care medicine, pediatric dentistry, pediatric endocrinology, pediatric emergency medicine, pediatric ethics, child gastroenterology, pediatric hematology/oncology, pediatric hospital medicine, pediatric infectious diseases, pediatric nephrology, pediatric optometry, pediatric otolaryngology, pediatric plastic surgery, pediatric pulmonology, pediatric radiology, pediatric rehabilitation, pediatric sports medicine, pediatric surgery, pediatric residency and med/peds residency

Cryptosporidium Priming Is More Effective Than Vaccine For Protection Against Cryptosporidiosis In A Murine Protein Malnutrition Model, Luther A. Bartelt, David T. Bolick, Glynis L. Kolling, James K. Roche, Edna I. Zaenker, Ana M. Lara, Francisco Jose Noronha, Carrie A. Cowardin, John H. Moore, Jerrold R. Turner, Cirle A. Warren, Gregory A. Buck, Richard L. Guerrant

Biochemistry and Molecular Biology Publications

Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates clinical features of severe cryptosporidiosis during malnutrition, we interrogated the effect of protein malnutrition (PM) on primary and secondary responses to C. parvum challenge, and tested the differential ability of mucosal priming strategies to overcome the PM-induced susceptibility. We determined that while PM fundamentally alters systemic and mucosal primary immune responses to Cryptosporidium, priming with C. parvum (106 oocysts) provides robust protective immunity against re-challenge despite ongoing PM. C. parvum priming restores mucosal Th1-type effectors (CD3+CD8+CD103+ T-cells) …

College Of Arts, Humanities, And Social Sciences Faculty Accomplishments Academic Year 2015-2016, Nova Southeastern University - College Of Arts, Humanities, And Social Sciences

CAHSS Faculty Accomplishments Summary

No abstract provided.

National Register Of Historic Places (Nrhp) Eligibility Determinations For Previously Recorded Archaeological Sites At Wright Patman Lake, Bowie And Cass Counties, Texas, Bryan C. Harrell, Chris Sypniewski, Alex Decaro, Nick Linville

Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State

Between 19 October and 11 November 2015, SEARCH conducted National Register of Historic Places (NRHP) eligibility determinations at previously recorded archaeological sites at Wright Patman Lake in Bowie and Cass Counties, Texas. This project was conducted under Contract W912HY-11-D-0002, Task Order 0006, between the US Army Corps of Engineers (USACE), Fort Worth District, and SEARCH.

The USACE, Fort Worth District, is proposing to raise and operate the current pool level at Wright Patman Lake to 228.64 feet (ft) above mean sea level (amsl), thereby meeting the Ultimate Rule Curve for the provision of water to the local area. The purpose …

Eliminating Antibiotic Use In Animal Production: Responding To Scientific Evidence Of An Impending Global Health Crisis, Sabrina R. Rearick

Duquesne Law Review

No abstract provided.

Leveraging Contact Network Structure In The Design Of Cluster Randomized Trials, Guy Harling, Rui Wang, Jukka-Pekka Onnela, Victor Degruttola

Harvard University Biostatistics Working Paper Series

Background: In settings like the Ebola epidemic, where proof-of-principle trials have succeeded but questions remain about the effectiveness of different possible modes of implementation, it may be useful to develop trials that not only generate information about intervention effects but also themselves provide public health benefit. Cluster randomized trials are of particular value for infectious disease prevention research by virtue of their ability to capture both direct and indirect effects of intervention; the latter of which depends heavily on the nature of contact networks within and across clusters. By leveraging information about these networks – in particular the degree …

Hydroxyurea Therapy For Children With Sickle Cell Anemia In Sub-Saharan Africa: Rationale And Design Of The Reach Trial, P. T. Mcgann, L. Tshilolo, B. Santos, G. A. Tomlinson, S. Stuber, T. Latham, B. Aygun, S. K. Obaro, P. Olupot-Olupot, R. E. Ware, +2 Additional Authors

Journal Articles

BACKGROUND: Sickle cell anemia (SCA) is an inherited hematological disorder that causes a large but neglected global health burden, particularly in Africa. Hydroxyurea represents the only available disease-modifying therapy for SCA, and has proven safety and efficacy in high-resource countries. In sub-Saharan Africa, there is minimal use of hydroxyurea, due to lack of data, absence of evidence-based guidelines, and inexperience among healthcare providers. PROCEDURE: A partnership was established between investigators in North America and sub-Saharan Africa, to develop a prospective multicenter research protocol designed to provide data on the safety, feasibility, and benefits of hydroxyurea for children with SCA. RESULTS: …

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Better Medicine, Lehigh Valley Health Network

Better Medicine

No abstract provided.