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Factors Associated With Sexually Transmitted Infections (Stis) And Multiple Sti Co-Infections: Results From The Evri Hiv Prevention Preparedness Trial, Ubin Pokharel

USF Tampa Graduate Theses and Dissertations

Objective: The objective of this study was to describe the prevalence of sexually transmitted co-infections and assess factors associated with a single infection and co-infections.

Methods: A total of 388 women were included in this study. At enrollment of the EVRI trial women were tested for five STIs: Human papilloma virus (HPV), Chlamydia trachomatis, Neisseria gonorrhoeae, Herpes simplex virus-2 (HSV-2) and Treponema pallidum. Prevalence of STI infections and proportion of women with different combinations of co-infections were calculated. Factors associated with single infection and STI co-infection were assessed using a polytomous logistic regression model and odds ratio …

Toward Earlier Inclusion Of Pregnant And Postpartum Women In Tuberculosis Drug Trials: Consensus Statements From An International Expert Panel., Amita Gupta, Jyoti S. Mathad, Susan M. Abdel-Rahman, Jessica D. Albano, Radu Botgros, Vikki Brown, Renee S. Browning, Liza Dawson, Kelly E. Dooley, Devasena Gnanashanmugam, Beatriz Grinsztejn, Sonia Hernandez-Diaz, Patrick Jean-Philippe, Peter Kim, Anne D. Lyerly, Mark Mirochnick, Lynne M. Mofenson, Grace Montepiedra, Jeanna Piper, Leyla Sahin, Radojka Savic, Betsy Smith, Hans Spiegel, Soumya Swaminathan, D Heather Watts, Amina White

Manuscripts, Articles, Book Chapters and Other Papers

Tuberculosis is a major cause of morbidity and mortality in women of childbearing age (15-44 years). Despite increased tuberculosis risk during pregnancy, optimal clinical treatment remains unclear: safety, tolerability, and pharmacokinetic data for many tuberculosis drugs are lacking, and trials of promising new tuberculosis drugs exclude pregnant women. To advance inclusion of pregnant and postpartum women in tuberculosis drug trials, the US National Institutes of Health convened an international expert panel. Discussions generated consensus statements (>75% agreement among panelists) identifying high-priority research areas during pregnancy, including: (1) preventing progression of latent tuberculosis infection, especially in women coinfected with human …

Week Of March 14, 2016, New York Medical College

InTouch

• SHSP Welcomes New Chairman of the Department of Health Policy and Management
• Camille A. Clare, M.D., M.P.H. '11, Is Named Interim Associate Dean of Diversity and Inclusion for the School of Medicine
• Department of Cell Biology and Anatomy Hosts Research Forum
• 60th Annual AOA Visiting Professor Lecture Set for March 23

Health Policy & Management News, Georgia Southern University

Health Policy & Community Health: News & Publications (2011-2018)

• Georgia Southern hosts the 2016 Healthcare Symposium, “Truths and Myths behind Childhood Vaccinations”
• Georgia Southern Conducts a State-Level Analysis of MCH Partnerships

My News

My News (2014-2020)

• Georgia Southern celebrates second annual Holi Festival March 24
• Beneath the Waves Film Festival set for March 24
• Childhood vaccinations topic of Healthcare Symposium
• Spring Break Dining Hours
• Marvin Pittman Lab School reunion held Sunday, March 6
• Tickets still available to hear award­winning journalists discuss informed voting

Summer 2016 | Tier Ii Applied Sciences Mathematics Online On Campus, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Awareness Of Rabies And Response To Dog Bites In A Bangladesh Community, Sumon Ghosh, Sukanta Chowdhury, Najmul Haider, Rajub K. Bhowmik, Md. S. Rana, Aung S. Prue Marma, Muhammad B. Hossain, Nitish C. Debnath, Be-Nazir Ahmed

Publications and Research

Community awareness regarding rabies and treatment seeking behaviours are critical both for the prevention and control of the disease in human and animals. We conducted a study to explore people’s awareness about rabies, their attitudes towards dogs and practices associated with treating dog bites in Satkhira Sadar, a southwestern sub-district of Bangladesh. Of the total 3200 households (HHs) surveyed, the majority of the respondents have heard about rabies (73%) and there was a high level of awareness that dog bite is the main cause of rabies (86%), and that rabies can be prevented by vaccination (85%). However, 59% of the …

Research Express News, Georgia Southern University

Research & Economic Development

• In its third year, Georgia Southern’s Master of Healthcare Administration (MHA) program and the Jiann-Ping Hsu College of Public Health will sponsor the 2016 Healthcare Symposium. “Truths and Myths behind Childhood Vaccinations,” on March 24, 10 a.m. – 11:30 p.m., in the University’s Performing Arts Center (PAC). The symposium is free and open to students, staff, faculty and the community.

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern celebrates second annual Holi Festival
• Georgia Southern hosts the 2016 Healthcare Symposium ," Truths and Myths behind Childhood Vaccinations"

Î?- Lactam-Induced Changes In Cell Wall Composition And Autolytic Properties Of Daptomycin Resistant Staphylococcus Aureus, Michael Krzyskowski

Theses and Dissertations

Staphylococcus aureus is a major human pathogen that is well known for its ability to develop resistance to antimicrobial therapies. Recent studies have identified a combination of β-lactam antibiotic and daptomycin (DAP) to be highly effective at killing single and multi-drug-resistant S. aureus. Of particular interest is this drug combinationâ??s efficiency with which it kills strains classified as DAP-resistant methicillin-resistant Staphylococcus aureus (DAP-R MRSA). The goals of the present study were two-fold: to provide a physiological profile of a DAP-R S. aureus strain undergoing beta-lactam treatment by observing changes in autolytic rate, susceptibility to lytic enzymes, levels of peptidoglycan O-acetylation, …

Summer 2016 | Introductory Online Courses For Nonmajors Animals Biodiversity Drugs The Brain Microbes, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Life Of The Scholar Event Planned Saturday, March 19 At Gardner-Webb University, Office Of University Communications

Gardner-Webb NewsCenter Archive

Gardner-Webb University will host the Life of the Scholar Multidisciplinary Conference, an annual showcase of students’ undergraduate and graduate research on Saturday, March 19, beginning at Dover Campus Center in Ritch Banquet Hall. The event is sponsored by Life of the Scholar (LOTS), an informal but dedicated group of GWU professors and students who work to take experiences from the classroom into the wider community. Other sponsors for the event are the Undergraduate Research program and Gardner-Webb’s chapter of Alpha Chi, the national multidisciplinary honor society.

Top Hiv/Aids Researcher Recruited To Uab For Leadership Post, Staff

Browse All News

No abstract provided.

Vaccine Expert Offit To Give 2016 Kennamer Distinguished Lecture In Montgomery, Uab Heersink School Of Medicine News

Browse All News

No abstract provided.

Discover Healthcare: Cultivating Interest In Health Careers In Underserved Youth Who Live In The Lehigh Valley, Jose Miguel Soto Ms

USF-LVHN SELECT

No abstract provided.

Expression Of Complement And Toll-Like Receptor Pathway Genes Is Associated With Malaria Severity In Mali: A Pilot Case Control Study, Rafal S. Sobota, Antoine Dara, Jessica E. Manning, Amadou Niangaly

Dartmouth Scholarship

Background: The host response to infection by Plasmodium falciparum, the parasite most often responsible for severe malaria, ranges from asymptomatic parasitaemia to death. The clinical trajectory of malaria is influenced by host genetics and parasite load, but the factors determining why some infections produce uncomplicated malaria and some proceed to severe disease remain incompletely understood.

Methods: To identify molecular markers of severe falciparum malaria, human gene expression patterns were compared between children aged 6 months to 5 years with severe and uncomplicated malaria who were enrolled in a case–control study in Bandiagara, Mali. Microarrays were used to obtain expression …

Cyclin-Dependent Kinase Crk9, Required For Spliced Leader Trans Splicing Of Pre-Mrna In Trypanosomes, Functions In A Complex With A New L-Type Cyclin And A Kinetoplastid-Specific Protein., Nitika Badjatia, Sung Hee Park, Daniela L. Ambrósio, Justin K. Kirkham, Arthur Günzl

UCHC Articles - Research

In eukaryotes, cyclin-dependent kinases (CDKs) control the cell cycle and critical steps in gene expression. The lethal parasite Trypanosoma brucei, member of the phylogenetic order Kinetoplastida, possesses eleven CDKs which, due to high sequence divergence, were generically termed CDC2-related kinases (CRKs). While several CRKs have been implied in the cell cycle, CRK9 was the first trypanosome CDK shown to control the unusual mode of gene expression found in kinetoplastids. In these organisms, protein-coding genes are arranged in tandem arrays which are transcribed polycistronically. Individual mRNAs are processed from precursor RNA by spliced leader (SL) trans splicing and polyadenylation. CRK9 …

Borrelia Burgdorferi Induces A Type I Interferon Response During Early Stages Of Disseminated Infection In Mice, Mary M. Petzke, Radha Iyer, Andrea Love, Zoe Spieler, Andrew Brooks, Ira Schwartz

NYMC Faculty Publications

BACKGROUND: Lyme borrelia genotypes differ in their capacity to cause disseminated disease. Gene array analysis was employed to profile the host transcriptome induced by Borrelia burgdorferi strains with different capacities for causing disseminated disease in the blood of C3H/HeJ mice during early infection.

RESULTS: B. burgdorferi B515, a clinical isolate that causes disseminated infection in mice, differentially regulated 236 transcripts (P < 0.05 by ANOVA, with fold change of at least 2). The 216 significantly induced transcripts included interferon (IFN)-responsive genes and genes involved in immunity and inflammation. In contrast, B. burgdorferi B331, a clinical isolate that causes transient skin infection but does not disseminate in C3H/HeJ mice, stimulated changes in only a few genes (1 induced, 4 repressed). Transcriptional regulation of type I IFN and IFN-related genes was measured by quantitative RT-PCR in mouse skin biopsies collected from the site of infection 24 h after inoculation with B. burgdorferi. The mean values for transcripts of Ifnb, Cxcl10, Gbp1, Ifit1, Ifit3, Irf7, Mx1, and Stat2 were found to be significantly increased in B. burgdorferi strain B515-infected mice relative to the control group. In contrast, transcription of these genes was not significantly changed in response to B. burgdorferi strain B331 or B31-4, a mutant that is unable to disseminate.

CONCLUSIONS: These results establish a positive association between the disseminating capacity of B. burgdorferi and early type I IFN induction in a murine model of Lyme disease.

21st Century Stem Reasoning, Robert L. Mayes Dr., Shawn Jackson

Interdisciplinary STEM Teaching & Learning Conference (2012-2019) (Archived)

The Georgia Southern University Real STEM Project is collaborating with 10 middle and high schools on development and implementation of an interdisciplinary STEM research and design course that actively engages students in real-world problem solving. We will discuss the expected outcomes of such interdisciplinary STEM experiences which is the development of 21st century STEM reasoning. Examples of using authentic teaching strategies to promote complex systems reasoning, model-based reasoning, computational reasoning, engineering design-based reasoning, and quantitative reasoning will be shared with participants.

Session C-1: Ecosystem Disruption: Using Lab And Real-World Examples To Bring Changes In Earth’S Ecosystems To Life, Crystal Randall, Sarah O'Leary-Driscoll, Sowmya Anjur, Don Dosch

Professional Learning Day

The magnitude of the changes occurring in Earth’s ecosystems seems difficult to tackle in the classroom and lab. Here we explore ways to demonstrate the changes in the Earth’s water and carbon cycles in the lab and bring them to life in real-world ecosystems in the classroom.

Jobe V. Dirne Clinic/Heritage Health Clerk's Record Dckt. 44604

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Uab Division Of Infectious Diseases Taps New Leadership, Staff

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No abstract provided.

The Lived Experience Of Pacific Island Women With A “Big Body” Size, Nafanua Braginsky, Merle Kataoka-Yahiro, Jillian Inouye

Asian/Pacific Island Nursing Journal

This phenomenological study explored the lived experience with "big body" size of Pacific Island women who migrated to Hawaii. Giorgi’s descriptive phenomenological approach was utilized in this study. A purposive sample included six Pacific Island women. Five of the six women had migrated to Hawaii from the island nations of Micronesia. The sixth participant was a Native Hawaiian who had lived in Micronesia and had returned to Hawaii. The collection and transcription of data were done by the first author. Data were categorized into themes independently by the three authors and bracketing was maintained throughout the study. The women identified …

Factors Affecting The Followup Status Of Hiv Infected Tuberculosis Patients Taking Haart Treatment At Jimma University Specialized Hospital, Aboma Temesgen Sebu

Journal of Statistics Applications & Probability

Highly active antiretroviral treatment is the life time treatment given for HIV/AIDS patients in order to reduce HIV related mortality and morbidity. Even if, the treatment is given to reduce the HIV mortality the reason of lost to followup from the treatment is unclear in most cases. The main objective of this study was also to determine the followup status and associated factors of HAART treatment for HIV infected tuberculosis patients during their followup period. The study considered a retrospective cohort 254 HIV infected tuberculosis patients whom age were 18 years and above taking HAART treatment at Jimma University specialized …

Decrease In Driveline Infections With Change In Driveline Management Protocol, Saima Aslam, Jennifer Dan, Amanda Topik, Michael Belyk, Francesca Torriani, Randy Taplitz, Jorge Silva-Enciso, Denise Barnard, Barry Greenberg, Jack Copeland, Victor Pretorius, Eric Adler

The VAD Journal

Background: Driveline infections (DLI) are a significant cause of morbidity and mortality in ventricular assist device (VAD) recipients. We compared driveline infection (DLI) rate after an institutional change in driveline management protocol.

Methods: We retrospectively reviewed records of left VAD recipients at our institution, based on driveline management. Group 1: daily driveline dressing change consisting of chlorhexidine cleansing, sterile 4x4 gauze, and use of an abdominal binder. Group 2: Dressing change every 3 days consisting of chlorhexidine cleansing, non-sterile silver-impregnated foam with overlying clear dressing, and use of a driveline anchor. Follow-up was censored at first DLI, device removal, transplant …

Dengue-Induced Autophagy, Virus Replication And Protection From Cell Death Require Er Stress (Perk) Pathway Activation, E. Datan, S. G. Roy, G. Germain, N. Zali, J. E. Mclean, G. Golshan, S. Harbajan, R. A. Lockshin, Z. Zakeri

Publications and Research

Avirus that reproduces in a host without killing cells can easily establish a successful infection. Previously, we showed that dengue-2, a virus that threatens 40% of the world, induces autophagy, enabling dengue to reproduce in cells without triggering cell death. Autophagy further protects the virus-laden cells from further insults. In this study, we evaluate how it does so; we show that dengue upregulates host pathways that increase autophagy, namely endoplasmic reticulum (ER) stress and ataxia telangiectasiamutated (ATM) signaling followed by production of reactive oxygen species (ROS). Inhibition of ER stress or ATM signaling abrogates the dengueconferred protection against other cell …

History, Trips, And Common Sense: Curbing The Counterfeit Drug Market In Sub-Saharan Africa, Hannah Elizabeth Jarrells

Georgia Journal of International & Comparative Law

No abstract provided.

Evaluating The Impact Of A Hiv Low-Risk Express Care Task-Shifting Program: A Case Study Of The Targeted Learning Roadmap, Linh Tran, Constantin T. Yiannoutsos, Beverly S. Musick, Kara K. Wools-Kaloustian, Abraham Siika, Sylvester Kimaiyo, Mark J. Van Der Laan, Maya L. Petersen

U.C. Berkeley Division of Biostatistics Working Paper Series

In conducting studies on an exposure of interest, a systematic roadmap should be applied for translating causal questions into statistical analyses and interpreting the results. In this paper we describe an application of one such roadmap applied to estimating the joint effect of both time to availability of a nurse-based triage system (low risk express care (LREC)) and individual enrollment in the program among HIV patients in East Africa. Our study population is comprised of 16;513 subjects found eligible for this task-shifting program within 15 clinics in Kenya between 2006 and 2009, with each clinic starting the LREC program between …

Behind The Bench Confessions Of An Accidental Lawyer, April 11, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

The Anchor, Volume 129.18: March 2, 2016, Hope College

The Anchor: 2016

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.