Digital Commons Network^™

“Whatdunit?” Developmental Changes In Children’S Syntactically-Based Sentence Interpretation Abilities And Sensitivity To Word Order, James W. Montgomery, Julia L. Evans, Ronald B. Gillam, Alexander V. Sergeev, Mianisha C. Finney

Special Education and Rehabilitation Counseling Faculty Publications

Aim 1 of this study was to examine the developmental changes in typically developing English-speaking children’s syntactically-based sentence interpretation abilities and sensitivity to word order. Aim 2 was to determine the psychometric standing of the novel sentence interpretation task developed for this study, as we wish to use it later with children with Specific Language Impairment (SLI). Children listened to semantically implausible sentences in which noun animacy and the natural affordance between the nouns were removed, thus controlling for event probability. Using this novel “whatdunit?” agent selection task, 256 children 7-11 years listened to two structures with canonical word order …

Tennessee Farm Bureau News - November 2016, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

Formulation And Characterization Of The Improved Solubility, In Vivo Bioavailability And Antioxidant Activity Of Apigenin-Phospholipid Complex (Aplc), Sridhar Anand, Darshan R. Telange, Arun T. Patil, Anil M. Pethe, Harshal Fegade, Vivek S. Dave

Pharmacy Faculty/Staff Publications

In the present study a phospholipid based complex of apigenin (APLC) was prepared with a goal of improving its aqueous solubility, dissolution, in vivobioavailability, and antioxidant activity.

Lubricant-Sensitivity Assessment Of Spress® B820 By Near Infrared Spectroscopy: A Comparison Of Multivariate Methods, Vivek S. Dave, Connor Mack, Heather Boyce, Enyioha Ike-Amaechi, Antione Al-Achi, Stephen W. Hoag, Rahul V. Haware

Pharmacy Faculty/Staff Publications

The aim of the present investigation was to compare the predictive performance of PCR and PLS calibration models based on near-infrared spectroscopy (NIRS) data used to monitor lubrication conditions impact on the tablet breaking force (TBF) of SPRESS® B820.

Assessing The Enhancement Of Aqueous Solubility Of Efavirenz Via Lyophilized Milk Based Solid Dispersion Formulations, Nishikant Raut, Pradip Dhore, Suprit Saoji, Vivek S. Dave

Pharmacy Faculty/Staff Publications

No abstract provided.

Influence Of Key Polymer Attributes, Manufacturing Conditions And Sintering On Abuse Deterrence Of Physical Barrier Type Abuse Deterrent Formulations (Adf), Heather Boyce, Vivek S. Dave, Myke Scoggins, Dan Smith, Steve Byrn, Bhawana Saluja, Wen Qu, Vadim J. Gurvich, Stephen W. Hoag

Pharmacy Faculty/Staff Publications

When sintering us used to treat tablet formulations containing polyethylene oxide (PEO), the polymer particles are able to form stronger bonds thereby increase tablet tensile strength. This increase in strength can make it more difficult for an abuser to break, chew, or grind opioid tablets. A mechanistic study was implemented to understand the key sintering factors that influence tensile strength.

An Effectiveness Survey Study Of Theophostic Prayer Ministry, Brigitte Ritchey

Doctoral Dissertations and Projects

This study assessed the perceived level of effectiveness of Thoephostic Prayer Minister (TPM) as measured by recipients’ overall and specific ratings of TPM’s impact on their lives, and assessed the validity of concerns that TPM leads to unusually high rates of negative outcomes. Method: Using a cross-sectional design, recipients completed a self-administered survey following their weekly session during one week of data collection at three different geographic locations across the United States. Data was analyzed for frequencies using one-way ANOVA’s. Results: Findings revealed 94% of respondents indicated that their overall problems improved, with 35% indicating the highest rating of improvement. …

Differences In Motivation And Game Scores Between Middle School Students Completing Digital Game-Based Learning Tasks With And Without Supports Of Autonomy And Structure, Joseph Harmon

Doctoral Dissertations and Projects

The purpose of this study was to determine the effect of autonomy and structure support on intrinsic motivation (IM), the facilitators of IM, and game scores during digital game-based learning (DGBL) tasks. The sample included 222 students in sixth, seventh, and eighth grade classrooms. Three instruments from the Intrinsic Motivation Inventory (IMI) were utilized during the study: (a) Perceived Choice; (b) Perceived Competence; and (c) Interest/Enjoyment. A quasi-experimental static-group comparison model research design was used to test the differences in perceived autonomy, perceived competence, interest/enjoyment, and game scores between four groups of middle school students completing online learning games in …

Job-Destroying Effects Of $15 Minimum Wage By Metro, Industry And Occupation, Andrew R. Hanson, Zackary Hawley

Economics Faculty Research and Publications

No abstract provided.

Getting Town Councils To Raise Their Game, Tan K. B. Eugene

Research Collection Yong Pung How School Of Law

Given that about 80 per cent of Singaporeans live in public housing estates, town councils are an integral part of Singapore life. Last month, the Ministry of National Development (MND) initiated a public consultation on the proposed amendments to the Town Councils Act (TCA), which was first enacted in 1988 to empower elected Members of Parliament and unelected town councillors to run public housing estates

The Murray Ledger And Times, November 1, 2016, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Erlotinib For Advanced Hepatocellular Carcinoma: A Systematic Review Of Phase Ii/Iii Clinical Trials, Jing Zhang, Yuan Zong, Gang-Zhu Xu, Ke Xing

Saudi Medical Journal

Objectives: To evaluate the efficacy and safety of erlotinib for the treatment of advanced hepatocellular carcinoma (HCC). Methods: A systematic literature search was undertaken in June 2015. Phase II/III trials of erlotinib for the treatment of advanced HCC were included. A descriptive analysis was applied. The study was conducted in College of Medicine, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China, between June 2015 and January 2016. Results: Ten trials, comprising 9 phase II and one phase III trial, were included in the systematic review. The tumor response rate was 0% in 4 of the phase II trials, <10% in 3 of the phase II trials and the phase III trial, and >20% in 2 …

Alfentanil Versus Ketamine Combined With Propofol For Sedation During Upper Gastrointestinal System Endoscopy In Morbidly Obese Patients, Ertugrul Kılıc, Barıs Demiriz, Nurgül Isıkay, Abdullah E. Yıldırım, Selman Can, Cem Basmacı

Saudi Medical Journal

Objectives: To observe the effects of both propofol/alfentanil and propofol/ketamine on sedation during upper gastrointestinal system endoscopy in morbidly obese patients (UGSEMOP). Methods: In a prospective, double-blinded, randomized clinical study, 52 patients scheduled for UGSEMOP were assigned to either group A (n=26; 10 µg/kg intravenous [IV] alfentanil) or group K (n=26; 0.5 mg/kg IV ketamine). Each patient was administered 0.7 mg/kg propofol for induction. If it was needed, the patients were administered an additional dose of IV propofol. This study was performed in Sehitkamil State Hospital, Gaziantep, Turkey, between January 2014-2015. Total propofol consumption, time to achieve Modified Aldrete Scores …

A Profile Of Out-Of-Hospital Cardiac Arrests In Northern Emirates, United Arab Emirates, Alan M. Batt, Ahmed S. Al-Hajeri, Fergal H. Cummins

Saudi Medical Journal

Objectives: To report the characteristics of out-of-hospital cardiac arrest patients and their outcomes in the emirates of Sharjah, Ras-al-Khaimah, Umm Al-Quwain, Fujairah, and Ajman in the United Arab Emirates (collectively known as the Northern Emirates). Methods: This is a prospective descriptive cohort study of out-of-hospital cardiac arrest incidents transported by the national ambulance crews between February 2014 and March 2015 in the Northern Emirates. Results: A total of 384 patients were enrolled in this study. Male victims of out-of-hospital cardiac arrest represented 76% of the participants. The mean age of the study population was 50.9 years. An over-all prehospital return …

Lung Cancer In Basrah, Iraq During 2005-2012: Incidence And Time Trend, Omran S. Habib, Jasim N. Al-Asadi, Osama G. Hussien

Saudi Medical Journal

Objectives: To study the incidence rate of lung cancer and its time trend in Basrah during 2005-2012. Methods: This was a cancer registry-based retrospective study including all Basrah inhabitant patients diagnosed with primary lung cancer during the period from January 2005 to December 2012. The crude incidence rate was calculated in addition to the age standardized incidence rate (ASIR)/100,000 using the world standard population. Results: Out of 746 registered cases of lung cancer in Basrah, 75.9% were males and 24.1% were females with a male: female gender ratio of 3.1:1. The crude incidence rate was 3.93/100,000 (5.89/100,000 for males and …

Low Bone Mineral Density Among Young Healthy Adult Saudi Women: Prevalence And Associated Factors In The Age Group Of 20 To 36 Years, Zeidan A. Zeidan, Intisar E. Sultan, Shaista S. Guraya, Abdulmohsen H. Al-Zalabani, Khalid I. Khoshhal

Saudi Medical Journal

Objectives: To screen for low bone mineral density among young adult Saudi women using quantitative ultrasound (QUS) and exploring the high risk groups. Methods: A cross-sectional study was performed on 279, 20-36 years old female students and employees of Taibah University, Al Madinah Al Munawwarah, Kingdom of Saudi Arabia between January and May 2014. The study included bone status assessed using QUS, a structured self-reported questionnaire, anthropometric measurements, and evaluation of bone markers of bone metabolism. Results: The prevalence of low bone mineral density was 9%. Serum osteocalcin was found significantly higher in candidates with low bone mineral density, 20.67 …

In This Issuesystematic Revieworiginal Articlescase Report

Saudi Medical Journal

No abstract provided.

Effect Of Iron Overload On Renal Functions And Oxidative Stress In Beta Thalassemia Patients, Mahmood Rasool, Arif Malik, Uzma Jabbar, Irshad Begum, Mahmood H. Qazi, Muhammad Asif, Muhammad I. Naseer, Shakeel A. Ansari, Jummanah Jarullah, Absarul Haque, Mohammad S. Jamal

Saudi Medical Journal

Objectives: To check the amount of cellular damage caused by serial transfusions of blood in thalassemia patients. Methods: A cross-sectional study was conducted in the University of Lahore, Lahore, Pakistan between August 2012 and December 2012. A total of 43 thalassemia patients underwent at least 10 blood transfusions. Comprehensive biochemical analysis of blood was performed to record the levels of creatinine, urea, uric acid, albumin, liver function tests, malondialdehyde (MDA), and ferritin. Results: Serum creatinine (0.732±0.23mg/dl) and uric acid (6.7±0.94mg/dl, p <0.05) were significantly higher in patient groups as compared with the control. Ferritin levels were significantly higher in patients as compared with the control (3103.9±1747.4, p <0.05). Hemoglobin levels were observed in controls 14±1.3g/dl and in patients 7.1±1.03g/dl. No clear relationship exists between age and hematological parameters of thalassemic patients. Serum ferritin level is positively related with serum alanine transaminase, aspartate aminotransferase, and alkaline phosphatase and MDA ( p <0.05). Conclusion: Serum MDA and serum ferritin of patients (r=0.593, p <0.05) reflects that both are crucial parameters estimating the cellular damage in patients suffering from thalassemia.

Institute For Scientific Information-Indexed Biomedical Journals Of Saudi Arabia: Their Performance From 2007-2014, Dileep K. Rohra, Vikram K. Rohra, Peter Cahusac

Saudi Medical Journal

Objectives: To compare the journal impact factor (JIF) and Eigenfactor score (ES) of Institute for Scientific Information (ISI)-indexed biomedical journals published from the Kingdom of Saudi Arabia (KSA) over the last 8 years. Methods: This is a retrospective study, conducted at Alfaisal University, Riyadh, KSA from January to March 2016. The Journal Citation Reports of ISI Web of Knowledge were accessed, and 6 Saudi biomedical journals were included for analysis. Results: All Saudi journals have improved their IF compared with their baseline. However, the performance of the Journal of Pharmaceutical Sciences and Neurosciences has been exceptionally good. The biggest improvement …

Diverse Etiology Of Hyperlipidemia Among Hospitalized Children In Western Region Of Saudi Arabia, Abdulmoein E. Al-Agha, Abrar M. Alnawab, Tala M. Hejazi

Saudi Medical Journal

Objectives: To determine the various etiologies of primary and secondary hyperlipidemia among children visiting the pediatric endocrine clinic. Methods: This is a retrospective, cross-sectional, cohort study conducted at King Abdulaziz University Hospital (KAUH), Jeddah, Kingdom of Saudi Arabia from January 2010 to 2015 that included 253 children aged from birth to 12 years old. Data were obtained by reviewing medical reports of patients who presented with hyperlipidemia to the clinic, and their laboratory investigation results using KAUH electronic “Phoenix” system. Results: Of the 253 children who were reviewed, those who have shown to have abnormal lipid metabolism with nephrotic syndrome …

Cochrane Review: Conclusions About The Effects Of Electronic Cigarettes Remain The Same

Saudi Medical Journal

No abstract provided.

Who Calls For Immediate Safe Evacuation Of The Sick And Wounded From Conflict Areas: Who Is Also Calling For A Halt Of Attacks On Health Care Workers And Facilities

Saudi Medical Journal

No abstract provided.

Who Urges Global Action To Curtail Consumption And Health Impacts Of Sugary Drinks

Saudi Medical Journal

No abstract provided.

Whither Gene Patenting And The Patenting Of Diagnostic Methods Post-Mayo And Myriad? The Need For Certainty In Navigating The High Seas Of Policy, Cheng Lim Saw

Research Collection Yong Pung How School Of Law

This paper is prompted by a series of recent high-profile decisions emanating from the apex courts in the US and Australia – namely, Mayo and Myriad – on the patent eligibility of gene-based inventions. Adopting a comparative approach, this paper critically examines whether isolated gene sequences and diagnostic methods qualify as patentable subject matter in several leading jurisdictions, including the US, Australia, Europe and the UK. An attempt will also be made, after carefully considering various arguments on both sides of the policy debate, at predicting what the future might hold (or, perhaps more accurately, at suggesting what the future …

Ibd Live Case Series-Case 6., Dhyan Rajan, Julia B. Greer, Miguel D. Regueiro, Leonard Baidoo, David G. Binion, Hans H. Herfarth, Corey A. Siegel, Douglas J. Hartman, Francis A. Farraye, Ioannis E. Koutroubakis, Myron H. Brand, Emmanuelle D. Williams, Alka Goyal, Raymond K. Cross

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Ambivalence: Prerequisite For Success In Motivational Interviewing With Adolescents?, Sarah W. Feldstein Ewing, Timothy R. Apodaca, Jacques Gaume

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND AND AIMS: The exploration and resolution of ambivalence play an essential role in motivational interviewing (MI) theory. However, most adolescent MI studies have not examined ambivalence as a contributor to behaviour change. This paper reviewed research findings on the role of ambivalence in the adolescent change process.

METHODS AND RESULTS: We undertook a narrative review of the published empirical and theoretical literature on ambivalence and mechanisms of change in MI for adolescents and found that current MI evaluations appear not to have access to reliable and valid measures of ambivalence in adolescence or neuroimaging methods to evaluate the mechanisms …

Shorter Remission Telomere Length Predicts Delayed Neutrophil Recovery After Acute Myeloid Leukemia Therapy: A Report From The Children's Oncology Group., Robert B. Gerbing, Todd A. Alonzo, Lillian Sung, Alan S. Gamis, Soheil Meshinchi, Sharon E. Plon, Alison A. Bertuch, Maria M. Gramatges

Manuscripts, Articles, Book Chapters and Other Papers

Purpose Suboptimal outcomes for children with acute myeloid leukemia (AML) necessitate maximally intensive therapy. Consequently, serious adverse events, such as prolonged periods of profound myelosuppression, contribute to AML treatment-related mortality. Telomeres, the repetitive DNA-protein structures at chromosome ends, influence cellular replicative capacity in that critically short telomeres can induce cell senescence or apoptosis. Our objective was to evaluate the impact of telomere length on duration of post-therapy neutropenia in a pediatric AML cohort. Patients and Methods Patients were diagnosed with de novo AML, enrolled in Children's Oncology Group study AAML0531, and included those with (n = 53) and without (n …

Toxic Environmental Exposures And Kidney Health In Children., Darcy K. Weidemann, Virginia M. Weaver, Jeffrey J. Fadrowski

Manuscripts, Articles, Book Chapters and Other Papers

High-level exposures to a number of agents are known to have direct nephrotoxic effects in children. A growing body of literature supports the hypothesis that chronic, relatively low-level exposure to various nephrotoxicants may also increase the risk for chronic kidney disease (CKD) or accelerate its progression. In this review we highlight several environmental nephrotoxicants and their association with CKD in children and adolescents. We also discuss unique epidemiological challenges in the use of kidney biomarkers in environmental nephrotoxicology.

Association Of Blood Pressure Variability And Neurocognition In Children With Chronic Kidney Disease., Marc B. Lande, Susan R. Mendley, Matthew B. Matheson, Shlomo Shinnar, Arlene C. Gerson, Joshua A. Samuels, Bradley A. Warady, Susan L. Furth, Stephen R. Hooper

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Children with chronic kidney disease (CKD) and hypertension have increased blood pressure variability (BPV), which has been associated with lower neurocognitive test scores in adults. Children with CKD are at risk for decreased neurocognitive function. Our objective was to determine whether children with CKD and increased BPV had worse performance on neurocognitive testing compared with children with CKD and lower BPV.

METHODS: This was a cross-sectional and longitudinal analysis of the relation between BPV and neurocognitive test performance in children ≥6 years enrolled in the Chronic Kidney Disease in Children (CKiD) study. Visit-to-visit BPV was assessed by the standard …

Effect Of Surgical Fusion On Volitional Weight-Shifting In Individuals With Adolescent Idiopathic Scoliosis, Nikhil T. Kurapati, Joseph Krzak, Adam Graf, Sahar Hassani, Sergey Tarima, Peter F. Sturm, Kim W. Hammerberg, Purnendu Gupta, Gerald F. Harris

Biomedical Engineering Faculty Research and Publications

Study Design

Prospective.

Objectives

The goals of this study were to (1) evaluate the differences in weightbearing symmetry between individuals with adolescent idiopathic scoliosis (AIS) and typically developing controls; (2) observe the effect of posterior spinal fusion and instrumentation (PSFI) on volitional weight-shifting at 1 and 2 years postoperatively; and (3) evaluate whether lowest instrumented fusion level (ie, lowest instrumented vertebra [LIV]) in PSFI has an effect on volitional weight-shifting.

Summary of Background Data

Previous studies have conflicting findings with regard to the effect of scoliosis on postural control tasks as well as the effect of surgery. They have also …