Digital Commons Network^™

Introduction To Direct Oral Anticoagulants And Rationale For Specific Reversal Agents., Charles V. Pollack

Department of Emergency Medicine Faculty Papers

No abstract provided.

Evidence Supporting Idarucizumab For The Reversal Of Dabigatran., Charles V. Pollack

Department of Emergency Medicine Faculty Papers

Idarucizumab is a monoclonal antibody fragment specifically targeted to dabigatran. It has demonstrated prompt and durable reversal of the anticoagulant effects of dabigatran in animal studies and phase 1 studies of young, elderly, and renally impaired volunteers. Although elective invasive procedures and most bleeding complications in dabigatran-treated patients can be managed by temporarily stopping dabigatran therapy and using supportive measures, there are rare clinical situations that require urgent reversal of the anticoagulant effect of dabigatran. The effectiveness and safety of 5 g of intravenous idarucizumab is being investigated in a prospective, open-label, single-cohort study in patients with serious bleeding or …

Duration Of Posttraumatic Amnesia Predicts Neuropsychological And Global Outcome In Complicated Mild Traumatic Brain Injury., Tessa Hart, Thomas A. Novack, Nancy Temkin, Jason Barber, Sureyya S. Dikmen, Ramon Diaz-Arrastia, Joseph Ricker, Dale C. Hesdorffer, Jack Jallo, Nancy H. Hsu, Ross Zafonte

Department of Neurosurgery Faculty Papers

OBJECTIVES: Examine the effects of posttraumatic amnesia (PTA) duration on neuropsychological and global recovery from 1 to 6 months after complicated mild traumatic brain injury (cmTBI).

PARTICIPANTS: A total of 330 persons with cmTBI defined as Glasgow Coma Scale score of 13 to 15 in emergency department, with well-defined abnormalities on neuroimaging.

METHODS: Enrollment within 24 hours of injury with follow-up at 1, 3, and 6 months.

MEASURES: Glasgow Outcome Scale-Extended, California Verbal Learning Test II, and Controlled Oral Word Association Test. Duration of PTA was retrospectively measured with structured interview at 30 days postinjury.

RESULTS: Despite all having a …

Assessing For Racial Disparity In The Use And Effects Of Disciplinary Segregation: A Propensity Score Matching Analysis, Ryan M. Labrecque

Criminology and Criminal Justice Faculty Publications and Presentations

Presentation focuses on impact of disciplinary segregation in correctional institutions

Changes In Serum Lipid Profile Among Patients Suffering From Chronic Liver Disease Secondary To Hepatitis C, Fakhar Qazi, Shameem Behram Khan, Anam Umar, Noor Ul Saba Shaikh, Fizza Choudhry

Section of Gastroenterology

Objective: To find out the changes in lipid metabolism among patients suffering from chronic liver disease secondary to hepatitis C.

Study Design: Hospital based observational study.

Setting: Medical Unit-I, Ward–5, Jinnah Postgraduate Medical Centre, Karachi.

Duration: July 2013 to December 2013.

Patients and Methods: About 110 patients admitted in Medical Unit-I with a diagnosis of chronic liver disease were included in the study. Patients suffering from DM, HTN, CKD were excluded from the study. Fasting lipid profile was done in all cases.

Results and Observations: There were 44 (40%) male and 66 (60%) female patients. Mean age of the patients …

Amulet: An Energy-Efficient, Multi-Application Wearable Platform, Josiah Hester, Travis Peters, Tianlong Yun, Ronald Peterson, Joseph Skinner, Bhargav Golla, Kevin Storer, Steven Hearndon, Kevin Freeman, Sarah Lord, Ryan Halter, David Kotz, Jacob Sorber

Dartmouth Scholarship

Wearable technology enables a range of exciting new applications in health, commerce, and beyond. For many important applications, wearables must have battery life measured in weeks or months, not hours and days as in most current devices. Our vision of wearable platforms aims for long battery life but with the flexibility and security to support multiple applications. To achieve long battery life with a workload comprising apps from multiple developers, these platforms must have robust mechanisms for app isolation and developer tools for optimizing resource usage.\r\n\r\nWe introduce the Amulet Platform for constrained wearable devices, which includes an ultra-low-power hardware architecture …

Multnomah County Project Launch Evaluation, Jessica Auerbach, Elana S. Emlen, Danielle C. Garcia, Noelle Hause, Callie H. Lambarth, Mhora Lorentson, Isabel M. Rife, Kathleen J. Zavela, Yumiko Aratani, Jeana R. Bracey, Mercedes Ekono, Beth L. Green, Rachel Kryah, Melissa Mendez, Sheila Smith, Lily Tom

Early Childhood

Early childhood is a critical time in human development. Any experience, positive or negative, can influence long-term outcomes for physical, emotional, social, and cognitive health (Center on the Developing Child at Harvard University, 2010). To ensure a strong foundation for success in school and in life, efforts designed to promote wellness and identify early learning or mental health challenges must begin well before kindergarten. Strong evidence shows that investing in early childhood can yield large dividends for children. Additionally, the ability of our systems to provide positive outcomes for children can be enhanced through strategic planning, well-developed partnerships, and coordinated …

Physicalism And Patent Theory, Christopher A. Cotropia

Vanderbilt Law Review

United States patent law's view on the need for a physical embodiment of the invention, and the continued production and use of an embodiment, has varied over the last two centuries. In the early days, the requirement for 'physicalism" was high, with the inventor being required to actually reduce the invention to practice prior to patenting, and enforceability was tied to "working" the claimed invention. By the early 1900s, these requirements of physicalism disappeared. This changing view on physicalism speaks volumes as to which major patent theory the law emphasizes, with physicalism supporting the incentive to invent theory and the …

Pierson, Peer Review, And Patent Law, Lisa L. Ouellette

Vanderbilt Law Review

When has a researcher done enough to merit a patent? Should the patent belong to the researcher who first suggests an invention or the one who brings it to fruition? The canonical dispute over a fox in Pierson v. Post is used to illustrate the competing policy considerations in deciding when to award a new property right, including providing efficient incentives, setting forth clear rules to guide future behavior, and respecting natural rights. In patent law, all of these considerations suggest that in practice, many patents are awarded too early, before an applicant has demonstrated that the invention is likely …

Currents In Fishery Management, Genevieve Depuy

University Honors Theses

This thesis provides an overview of fishery management policy types and attempts to determine best practices for biological sustainability in terms of species preservation and biomass recovery. Key concepts include biological sustainability, regulatory forces, and fishery management and output trends. The research question investigated is: what are the best policy practices for regulating marine fishery health and biological stability? The research process of this paper included a review of prior literature in the field of marine policy and fishery management, as well as the use of United States data from the Pacific and Atlantic coasts to evaluate management strategies. Based …

The Interest Rate Effect On Private Saving: Alternative Perspectives, Joshua Aizenman, Yin-Wong Cheung, Hiro Ito

Economics Faculty Publications and Presentations

Using an uneven panel of 135 countries from 1995 to 2014, we investigate the link between interest rates and private saving, and focus on whether the interest rate effect is dominated by the income (i.e., negative) or the substitution (i.e., positive) effect. With the baseline estimation, we find that the real interest rate has the substitution effect on private saving only for a full-country sample and a group of Asian economies. We also examine if low real - or nominal - interest rates have any impact on the link between the real interest rate and the private saving rate. We …

The Pacific Sentinel, November 2016, Portland State University. Student Publications Board

The Pacific Sentinel

Editor: Alex Skousen

Articles in this issue include:

• Grass Roots;
• Under the Sun;
• Get Off the Damn Sidewalk;
• Bagel Memorial;
• Protest Against New Police Contract;
• Pop Quiz: Understanding Andy;
• 22. A Million: Album Review;
• Getting Mystical With Alan Moore's Jerusalem;
• Denial;
• Sustainability; and
• Comics.

Hidden Markov Chain Analysis: Impact Of Misclassification On Effect Of Covariates In Disease Progression And Regression, Haritha Polisetti

USF Tampa Graduate Theses and Dissertations

Most of the chronic diseases have a well-known natural staging system through which the disease progression is interpreted. It is well established that the transition rates from one stage of disease to other stage can be modeled by multi state Markov models. But, it is also well known that the screening systems used to diagnose disease states may subject to error some times. In this study, a simulation study is conducted to illustrate the importance of addressing for misclassification in multi-state Markov models by evaluating and comparing the estimates for the disease progression Markov model with misclassification opposed to disease …

Plastin 1 Widens Stereocilia By Transforming Actinfilament Packing From Hexagonal To Liquid, Jocelyn F. Krey, Evan S. Krystofiak, Rachel A. Dumont, Sarath Vijayakumar, Dongseok Choi, Francisco Rivero, Bechara Kachar, Sherri M. Jones, Peter G. Barr‑Gillespie

OHSU-PSU School of Public Health Faculty Publications and Presentations

With their essential role in inner ear function, stereocilia of sensory hair cells demonstrate the importance of cellular actin protrusions. Actin packing in stereocilia is mediated by cross-linkers of the plastin, fascin, and espin families. Although mice lacking espin (ESPN) have no vestibular or auditory function, we found that mice that either lacked plastin 1 (PLS1) or had nonfunctional fascin 2 (FSCN2) had reduced inner ear function, with double-mutant mice most strongly affected. Targeted mass spectrometry indicated that PLS1 was the most abundant cross-linker in vestibular stereocilia and the second most abundant protein overall; ESPN only accounted for ∼15% of …

Portland Green Loop Economic Analysis, Jenny H. Liu

Northwest Economic Research Center Publications and Reports

The Portland “Green Loop” is a proposed 6-mile linear open space running through the heart of the city, connecting existing and new open spaces, parks, gathering areas, and walking and biking pathways. As envisioned, the Green Loop concept requires significant infrastructure investments, and would result in both short-term and long-term impacts on transportation (for all travel modes), environment and economic development. The goal of this project is to characterize, quantify and analyze these costs, benefits and impacts, particularly focusing on case studies of similar infrastructure investments in active transportation and analyses of property value impacts, economic (input-output) impacts and preliminary …

Amendment Creep, Jonathan L. Marshfield

Michigan Law Review

To most lawyers and judges, constitutional amendment rules are nothing more than the technical guidelines for changing a constitution’s text. But amendment rules contain a great deal of substance that can be relevant to deciding myriad constitutional issues. Indeed, judges have explicitly drawn on amendment rules when deciding issues as far afield as immigration, criminal procedure, free speech, and education policy. The Supreme Court, for example, has reasoned that, because Article V of the U.S. Constitution places no substantive limitations on formal amendment, the First Amendment must protect even the most revolutionary political viewpoints. At the state level, courts have …

Semiological Classification Of Psychogenic Nonepileptic Seizures., Ali Akbar Asadi-Pooya, Jennifer Tinker, Elizabeth W. Fletman

Department of Neurology Faculty Papers

PURPOSE: We classified patients with psychogenic nonepileptic seizures (PNESs) according to a newly proposed classification system. Then, we investigated the demographic and clinical differences between various classes of the patients.

METHODS: We retrospectively investigated all patients with PNESs admitted to the Jefferson Comprehensive Epilepsy Center from 2012 through 2016. We classified the patients into four distinct classes: patients with generalized motor seizures, patients with akinetic seizures, patients with focal motor seizures, and patients with seizures with subjective symptoms. All patients were interviewed by a neuropsychologist and were administered psychological assessment measures, including questions about PNES risk factors. For the statistical …

Both Sides Now: Vendors And Librarians--Learning How To Embrace The Concept Of "Change", Michael Gruenberg

Against the Grain

No abstract provided.

Reforming Regulation, Ganesh Sitaraman

Vanderbilt Law School Faculty Publications

The debate over federal regulation has long been at the center of political contests. But surprisingly, the degree of agreement about regulation is considerable. No serious commentator denies that regulation is essential to ensuring well-functioning markets; protecting the health and safety of workers and families; and preventing fraud, corruption, and theft. Smart regulation is what makes cars safe to drive, lakes and rivers safe to swim in, and food safe to eat. At the same time, every serious commentator recognizes that poorly designed regulations can be detrimental; they can stack the deck in favor of special interests, prevent competition, and …

Deeper Than Roots, Braelyn D. Spencer

All NMU Master's Theses

This collection of essays explores the author’s relationship with home. The author works through family, death, relationships, illness, and growth. The essays consist of an analysis of rooms within a house, the act of burying loved ones, and discovering what it is to move away. These essays aim to mix retellings of everyday events and relationships with deep personal turmoil and the growth that result from it.

Spatial Analysis Of Landfills In Respect To Flood Events And Sea-Level Rise, Benjamin S. Taylor, Songlin Fei

Purdue GIS Day

Recently in the news, media coverage of flood events has garnered much attention due to tropical storms like Hurricane Matthew and the costly damages that resulted. Under climate change, events like sea-level rise (SLR) and flooding threaten infrastructure, which make it necessary for proper planning before, during, and after installation to mitigate risk. Studies in Austria and the UK have revealed that many landfills are located in flood zones as well as coastal areas effected by coastal erosion. In the U.S. however, there have not been publications on landfill locations related to flood events and SLR. The interest of gaining …

Table Of Contents

Against the Grain

No abstract provided.

And They Were There--Reports Of Meetings, Ramune K. Kubilius

Against the Grain

No abstract provided.

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Against the Grain

No abstract provided.

Being Earnest With Collections--Let's Get In Formation: Standardized Data Review For Eresource Management, Kelli Getz, Michael A. Arthur, Lindsay Cronk

Against the Grain

No abstract provided.

From The Reference Desk--Reviews Of Reference Titles, Tom Gilson

Against the Grain

No abstract provided.

Textselect Revisited: The Evolution And Success Of The Textbook Reserves Program At George Mason University, Jessica Bowdoin, Madeline Kelly

Against the Grain

No abstract provided.

Decoder Ring--Ala Takeaways And Fall Follow-Ups, Jerry Spiller

Against the Grain

No abstract provided.

English Teacher Preparation, Budget Cuts, And Kuhn’S Theory Of Paradigm Shifts: A Closer Look At Content Area Feedback During Student Teaching, Elizabeth Brockman

Language Arts Journal of Michigan

No abstract provided.

Annotated Bibliography Of Research In The Teaching Of English, Jessica Dockter Tierney, Ann Mogush Mason, Amy Frederick, Richard Beach, Blanca Caldas, Anne Crampton, Jenna Cushing-Leubner, Lori Helman, Anne Ittner, Ezekiel Joubert, Keitha-Gail Martin-Kerr, Tiffany Nielsen-Winkelman, Debra Peterson, Abigail Rombalski, Kay Rosheim, Andrew Rummel, Lauren Aimonette, Kris Isaacson, Tanja Janssen, Michael Madson, Maggie Struck, Kathryn Allen, Madeleine Israelson, Heidi Jones, Lisa Ortmann, Mark Sulzer, Amanda Haertling Thein

Teaching & Learning Faculty Publications

No abstract provided.