Digital Commons Network^™

Exendin 4 Conjugation And Sequence Modification To Treat Type 2 Diabetes And Obesity, Ronald Bonaccorso Bonaccorso

Dissertations - ALL

This thesis addresses three primary questions based on the pharmacodynamics (PD) or pharmacokinetics

(PK) of the diabetes drug exendin 4 (Ex-4), and vitamin B12 (B12) bioconjugates, thereof.

Q1. (Chapter 2) What effect does B12 conjugation to Ex-4 have on agonism of the glucagon-like peptide-1

receptor (GLP-1R) in vitro and on PD/PK (including brain uptake and function) in vivo?

Goal: To remove side-effects (nausea, weight loss) of Ex-4 without loss of glucoregulation.

Q2. (Chapter 3) Can B12 dietary uptake proteins such as gastric intrinsic factor offer protection to B12

conjugated peptides or proteins (focusing on Ex-4), with a view to improving …

Sensor Management For Localization And Tracking In Wireless Sensor Networks, Nianxia Cao

Dissertations - ALL

Wireless sensor networks (WSNs) are very useful in many application areas including battlefield surveillance, environment monitoring and target tracking, industrial processes and health monitoring and control. The classical WSNs are composed of large number of densely deployed sensors, where sensors are battery-powered devices with limited signal processing capabilities. In the crowdsourcing based WSNs, users who carry devices with built-in sensors are recruited as sensors. In both WSNs, the sensors send their observations regarding the target to a central node called the fusion center for final inference. With limited resources, such as limited communication bandwidth among the WSNs and limited sensor …

Investigating Barriers To Mental Health Care In Law Enforcement Officers, Samantha F. Johnson

Electronic Theses and Dissertations

The profession of law enforcement is an inherently stressful job. Although the physical stress of the job is often discussed, the mental health impact on officers is often ignored, resulting in poor mental health and increased risk for suicide. The purpose of the current study was to investigate factors related to the reluctance of law enforcement officers (LEOs) to seeking treatment, as well as to gain an understanding of the prevalence rates of disorders in a law enforcement population. Convenience sampling was used to recruit participants (N = 306) across a variety of agencies. Correlation, moderated regression analysis, and structural …

Enhancing Vegetable Intake In Infants And Toddlers Through Parental Complementary Feeding Education, Sophia Testa

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This research project investigated the outcomes of educating parents of infants between the ages of 6 months and 12 months on the importance of including vegetables in complementary feedings on the infant’s vegetable consumption. The efficiency of teaching was measured by comparing physical measurements and quantity of vegetables consumed by infants whose parents received education with the same data from infants whose parents did not receive education on inclusion of vegetable in complementary feedings. The results found contributed to Dr. Shreve’s research on childhood obesity in the Northwest Arkansas population and to the knowledge of parental education with regard to …

Vocational And Life Skills Quarterly Report: Quarter 2 (October-December 2016), Uno Nebraska Center For Justice Research, Johanna Peterson, Jordan Clark

Reports

The Vocational and Life Skills Program was created by Nebraska Legislative Bill 907 in 2014 with the goals of reducing recidivism and increasing employment for individuals who are incarcerated, who have been incarcerated within the prior 18 months or who are under parole or probation supervision. Participants must begin programming under these conditions, but they may continue programming as the program sees fit for his or her individual needs. Eight programs were funded in Grant Cycle 2 which runs from July 2016-June 2018. The NCJR evaluation was initiated in May 2016 with the primary goal of identifying types of programming …

Vocational And Life Skills Monthly Data Update: December 2016, Uno Nebraska Center For Justice Research, Johanna Peterson

Reports

Grantees use an online data management system to submit data on participants served under their Vocational and Life Skills programming. This data is due monthly and reflects all services provided during the previous month to participants. Evaluators at the Nebraska Center for Justice Research work with grantees directly to correct any data errors on an ongoing basis during monthly update calls and site visits.

Data presented below is from the monthly data pulls. Because this data comes for an active database with live data being entered and updated daily, data, including previously submitted information, may fluctuate depending on changes made …

Digital Citizenship In 21st Century Education, Aimee Green Logan

Dissertations, Masters Theses, Capstones, and Culminating Projects

Recent Federal Government initiatives have affected equitable public school funding, which prevents many schools from becoming compliant with the California Common Core Standards. Presently, public schools in California must adopt Common Core State standards, which require the integration of technology within the classroom, however, there are no specific standards and or guidelines within the CCCS that address how students should safely conduct themselves online. This has left students and teachers unprepared to adequately support the growing needs of students online, especially without standards addressing digital literacy. Students who go online face cyberbullying, predatory contact, identity theft and other consequences that …

North Santiam School District Population And Enrollment Forecasts, 2017-18 To 2031-32, Portland State University. Population Research Center, Charles Rynerson, Scott Stewart, Nicholas Chun

School District Enrollment Forecast Reports

This report presents a series of three scenarios of district-wide enrollment forecasts by grade level for the North Santiam School District (NSSD) for the 15-year period between 2017-18 and 2031-32. Each enrollment forecast scenario is related to population forecasts that incorporate different assumptions about growth within the District, with the primary differences being the contribution of net migration to the District’s population and age distribution. Individual school forecasts consistent with the middle series scenario are also presented for the 15-year period.

2016 Winter Graduate & Undergraduate Commencement, Lindenwood University

Commencement Programs

Lindenwood University Commencement program.

Towards An Anthropometric History Of Latin America In The Second Half Of The Twentieth Century, Amílcar E. Challú, Sergio Silva-Castañeda

History Faculty Publications

We examine the evolution of adult female heights in twelve Latin American countries during the second half of the twentieth century based on demographic health surveys and related surveys compiled from national and international organizations. Only countries with more than one survey were included, allowing us to cross-examine surveys and correct for biases. We first show that average height varies significantly according to location, from 148.3 cm in Guatemala to 158.8 cm in Haiti. The evolution of heights over these decades behaves like indicators of human development, showing a steady increase of 2.6 cm from the 1950s to the 1990s. …

Mammographic Density Assessed On Paired Raw And Processed Digital Images And On Paired Screen-Film And Digital Images Across Three Mammography Systems, Anya Burton, Graham Byrnes, Jennifer Stone, Rulla M. Tamimi, John Heine, Celine Vachon, Vahit Ozmen, Ana Pereira, Maria Luisa Garmendia, Christopher Scott, John H. Hipwell, Caroline Dickens, Joachim Schüz, Mustafa Erkin Aribal, Kimberly Bertrand, Ava Kwong, Graham G. Giles, John Hopper, Beatriz Pérez Gómez, Marina Pollán, Soo-Hwang Teo, Shivaani Mariapun, Nur Aishah Mohd Taib, Martín Lajous, Ruy Lopez-Riduara, Megan Rice, Isabelle Romieu, Anath Arzee Flugelman, Giske Ursin, Samera Qureshi, Huiyan Ma, Eunjung Lee, Reza Sirous, Mehri Sirous, Jong Won Lee, Jisun Kim, Dorria Salem, Rasha Kamal, Mikael Hartman, Hui Miao, Kee-Seng Chia, Chisato Nagata, Sudhir Vinayak, Rose Ndumia, Carla H. Van Gils, Johanna O. P. Wanders, Beata Peplonska, Agnieszka Bukowska, Steve Allen, Sarah Vinnicombe, Sue Moss, Anna M. Chiarelli, Linda Linton, Gertraud Maskarinec, Martin J. Yaffe, Norman F. Boyd, Isabel Dos-Santos-Silva, Valerie A. Mccormack

Imaging & Diagnostic Radiology, East Africa

Background: Inter-women and intra-women comparisons of mammographic density (MD) are needed in research, clinical and screening applications; however, MD measurements are influenced by mammography modality (screen film/ digital) and digital image format (raw/processed). We aimed to examine differences in MD assessed on these image types.

Methods: We obtained 1294 pairs of images saved in both raw and processed formats from Hologic and General Electric (GE) direct digital systems and a Fuji computed radiography (CR) system, and 128 screen-film and processed CR-digital pairs from consecutive screening rounds. Four readers performed Cumulus-based MD measurements (n = 3441), with each image pair read …

Murine Models Of Splenic Marginal Zone Lymphoma: A Role For Cav1?, Chelsey L. Patten, Christine E. Cutucache

Biology Faculty Publications

Dozens of murine models of indolent and aggressive B-cell lymphomas have been generated to-date. These include those manifesting chronic lymphocytic leukemia (CLL), diffuse large B-cell lymphoma (DLBCL) as well as xenografts of mantle cell lymphoma (MCL). These models have led to an improved understanding of disease etiology, B-cell biology, immunomodulation, and the importance of the tumor microenvironment. Despite these efforts in CLL, DLBCL, and MCL, considerably little progress toward a model of splenic marginal zone lymphoma (SMZL) has been accomplished. Herein, we describe the similarities and differences between CLL, MCL, and SMZL, and highlight effective murine models that mimic disease …

Carriers For The Tunable Release Of Therapeutics: Etymological Classification And Examples, Vuk Uskoković, Shreya Ghosh

Pharmacy Faculty Articles and Research

Introduction—Physiological processes at the molecular level take place at precise spatiotemporal scales, which vary from tissue to tissue and from one patient to another, implying the need for the carriers that enable tunable release of therapeutics.

Areas Covered—Classification of all drug release to intrinsic and extrinsic is proposed, followed by the etymological clarification of the term “tunable” and its distinction from the term “tailorable”. Tunability is defined as analogous to tuning a guitar string or a radio receiver to the right frequency using a single knob. It implies changing a structural parameter along a continuous quantitative scale and …

News & Events

Journal of Asian Midwives (JAM)

No abstract provided.

Strengthening The Knowledge And Skills Of Community Midwives In Pakistan Through Clinical Practice Internships, Arusa Lakhani, Rafat Jan, Kiran Mubeen, Sadia Karimi, Shahnaz Shahid, Rozina Sewani, Marina Baig, Farzana Adnan

Journal of Asian Midwives (JAM)

Objective: On the-job training of Community Midwives (CMWs) is of critical importance in enabling midwives to provide services that meet standards of quality care. The objective of this study was to assess the intervention of an internship for CMWs that would increase their ability to provide quality maternal, newborn, and child health services.
Method: A pre and post-intervention design was used to evaluate the effectiveness of an internship of 32 working days. Validated questionnaire was used to assess the CMWs’ knowledge and skills before and after the intervention. Overall, 252 CMWs from 14 districts of the Sindh and …

‘Competent, But Not Allowed To Blossom’: Midwifery-Trained Registered Nurses’ Perceptions Of Their Service: A Qualitative Study In Sri Lanka, Sunethra Jayathilake, Vathsala Jayasuriya-Illesinghe, Rasika Perera, Himani Molligoda, Kerstin Samarasinghe

Journal of Asian Midwives (JAM)

Objective: To explore midwifery-trained registered nurses’ perceptions of their own profession as maternity care providers and how they identify their role, tasks, and responsibilities within a multi-professional team.
Design: An exploratory qualitative study using focus group discussions and qualitative content analysis.
Setting: Three selected tertiary care hospitals in the Capital Province in Sri Lanka.
Participants: Twenty-two midwifery-trained RNs working in intra-partum and postpartum units.
Findings: The overriding theme of the analysis was identified as ‘competent but not allowed to blossom fully in their practice’, based on two main categories: ‘provision of competent care’ and ‘working with disappointments’. Each main …

Effectiveness Of Video-Assisted Teaching On No-Scalpel Vasectomy On Knowledge And Attitude Of Married Men In Rural Nagaland, India, Arhoni Tungoe

Journal of Asian Midwives (JAM)

This study assessed whether video-assisted teaching increased the knowledge of,and resulted in a more favourable attitude among married men regarding No-Scalpel Vasectomy (NSV) in a selected village of 17,000 people,bordering Assam, in Nagaland, India. The study used a one group,before-and-after design. The participants were 30 married men who were selected through purposive sampling. Pre-tested and validated tools to assess knowledge and attitudes were used for data collection. The mean post-test scores, on both the knowledge and attitude scales,showed a significant increase from pretest scores (knowledge pre-test mean 11.53±3.41; post-test 21.23±2.18;attitude pre-test mean 20.87±2.64, post-test35.2±1.66).Thus we conclude that the video-assisted teaching …

Adolescent Pregnancies: The Case Of Pakistan, Kiran Mubeen, Marina Baig

Journal of Asian Midwives (JAM)

Early motherhood not only causes poor health outcomes, but often also deprives adolescent girls of educational, social, and economic development opportunities for the rest of their lives. Evidence suggests that although the burden of adolescent pregnancies is less in Pakistan than in Bangladesh, Afghanistan and Nepal, the pregnancy outcomes continue to be devastating in this country. This paper discusses the social barriers in addressing this issue in Pakistan and proposes recommendations for targeted interventions to reduce the high birth rate amongst adolescents in the country. The role of midwives asfrontlinegatekeepers can be pivotal for prevention ofteenagedpregnancies in Pakistan. Unfortunately, the …

Final Design Report: Allergen Mixing Assistant (Ama) Micro-Refrigeration Redesigning, Mitchell Parks, Minwoo (Michael) Suh

Mechanical Engineering

Abstract

Allergen Mixing Assistant (AMA) by Xtract Solutions is a device designed to more “effectively refrigerate, organize, and mix allergenic extracts”. Although Xtract Solutions intended the product to be fully automated, the company has decided against its automation and declared its current design as a minimum viable product whose components are too expensive, difficult to source and complex. Therefore, Cal Poly AMA design team - Mitchell Parks and Minwoo Suh - has decided to replace these expensive components with much more economical alternatives as shown below:

Stirling cooler

→

Thermoelectric (Peltier) cooler

Custom Arduino

Controller Card

→

TEC Thermostat *** …

Biofuel Gasification For Residential Heating, Bryan Duke, Courtney Mcintosh, Jeron Hogan

Mechanical Engineering

No abstract provided.

Heroin Addiction And Recovery: An Interpretative Phenomenological Analysis, Julia C. Rossini

Social Work Theses - Archive

This study is an interpretative phenomenological analysis of the human experience of heroin addiction and recovery. Literature on heroin addiction suggests that those who struggle with addiction are likely to also struggle with impulsivity, self-efficacy, and mood. The literature also finds that group membership is a common factor in recovering from addiction, whether that be in an Alcoholics Anonymous/Narcotics Anonymous group or harm-reduction community. Two theories were explored, the social learning theory and self- medication theory. The study was shaped by the ideas and findings of previous literature and theories and narrowed down to one specific research question not yet …

Resilience In Seeking Refuge: Religious Coping Strategies In Muslim Refugees From Syria, Nabiha Hasan

Social Work Theses - Archive

The recent shift of attention onto Syrian refugees has resulted in much media coverage and discussion regarding this population. This study delved into the religious coping strategies of Muslim refugees from Syria. Participants were derived through a DFW-based nonprofit organization. Questions asked of participants were including but not limited to resiliency and religious coping mechanisms. Major themes developed from this study included: religious ideologies, challenges as new religious minorities in the United States, resettlement issues, and benefits of resettlement. Results showed high correlation between resilience and religious beliefs.

Notes From The Director, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Full Issue, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

About The Mcnair Scholars Program, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Active Contact Lens - Low Power Backscattering Sensor-To-Antenna Integration Circuitry, Caleb B. Porter

Electrical Engineering

The Active Contact Lens measures the cornea-scleral radius of the wearer’s eye, which correlates to intraocular pressure (IOP), Glaucoma’s primary indicator. IOP varies throughout the day, and is drastically different from person to person, so constantly measuring it over a period of a few days can provide individualized tracking of the disease’s development and will help doctors develop personalized treatment schedules to treat the disease more precisely.

The Active Contact Lens sensor measures strain, based on the cornea-scleral radius, and reports the results wirelessly, to allow monitoring of an individual’s IOP over time. The lens is powered similarly to a …

Designing A Power Distribution System For The Arce 257 Revit Structural Model, Reid Wilhelm

Electrical Engineering

The construction industry needs engineers. Mechanical, electrical, and plumbing engineers, better known as MEPs, comprise a large number of employees who design and assist in the building of commercial structures. In particular, electrical engineers design power distribution systems for these buildings, including the power, lighting, low voltage, and fire protection subsystems.

Here at Cal Poly, architectural engineers enrolled in ARCE 257 create authentic structural plans for a fictitious two-story structure. This senior project transforms these structural plans into an architectural model and creates a power distribution system for the entire building. This is done through a building information modeling (BIM) …

Experimental Evaluation Of Structural Steel Coating Systems, Elias Anis Toubia, Sadra Emami

Civil and Environmental Engineering and Engineering Mechanics Faculty Publications

Departments of transportation (DOTs) currently use the conventional three-coat system as the predominant choice for the corrosion protection of steel bridge structures. Eliminating one step in the coating process could potentially save time and cost associated with lane closures and traffic control costs. This research paper evaluates several two-coat systems based on the zinc-rich primer and polysiloxane topcoat technology. All samples were conditioned and coated in a state-of-the-art, climate-controlled paint booth, simulating common field ENvironmental CONditions (ENCON) (ENCON 1: 25 °C/50% RH, ENCON 2: 10 °C/40%RH, and ENCON 3: 32°C/80% RH). Accelerated weathering tests were performed on 435 coated samples …

Review — Black Practical Theology, Edited By Dale P. Andrews And Robert London Smith Jr., C. Vanessa White

Journal of the Black Catholic Theological Symposium

No abstract provided.

The Risk Of Memory, The Cost Of Forgetting, M. Shawn Copeland

Journal of the Black Catholic Theological Symposium

This article, a revision of the Raymund Schwager, S.J., Memorial Lecture, given at the Colloquium on Religion and Violence, July 10, 2015, St. Louis University, focuses on the risk of memory and the cost of forgetting. Memory, and the act of remembering both individually and collectively as a society, involves risk to a society’s present, past, and future. Forgetting comes at a price exacted by the past, but paid in the present for the future, even as nations sometimes choose to forget. This thesis is developed in three parts – common meaning and memory as grounding a community; the cost …