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Tnf-Like Weak Inducer Of Apoptosis (Tweak) : Not So Weak After All., Joseph Dekward Mcmillan Iv

Electronic Theses and Dissertations

Background: Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a proinflammatory cytokine belonging to the TNF super family. TWEAK produces a variety of cellular responses through the binding to fibroblast growth factor inducible 14 (Fn14), a member of TNF receptor superfamily. Although Fn14 lacks a death domain, TWEAK has been found to induce apoptosis in some cell types by perturbing the activity of certain pathways such as TNF-receptor signaling. TWEAK is also known to regulate proliferation and differentiation of myogenic cells. We have previously reported that the TWEAK-Fn14 system causes skeletal muscle wasting both in vitro and in …

Comparison Of Two Methods For Developing Aggregate Population-Based Models, Oyebola E. Oyero

Electronic Theses and Dissertations

Aggregate models incorporate the variation between individual parameters of individualbased models to construct a population-based model. This thesis focuses on the comparison of two different methods for creating these population-based models. The first method, the individual parameter distribution technique (IPD) focuses on the similarities and variation of parameters in an individual-based model as calculated using individual data sets [4]. The second method we consider is the nonlinear mixed effect method (NLME), which is primarily used in modeling repeated measurement data. In the NLME approach, both the fixed effects and random effects of the parameter values are estimated in the model …

Um Welcomes 'New Friends And Kindred Spirits', Katie Morrison

University of Mississippi News

University's freshman class of Stamps Scholars is nation's third-largest

Effects Of Negative Online Word-Of-Mouth On Consumer Evaluations Of An Underdog Brand, Anja P. Luethi

Senior Honors Theses

Research on underdogs has suggested that consumers feel sympathy for and a desire to support the underdog. However, it is unclear how their evaluations of the underdog will change if they receive negative information about it. The current research aims to explore the role of negative word-of-mouth of the underdog, compared to the top dog, in consumers’ brand attitude, brand value, and purchase intention. Specifically, drawing on two streams of research, two competing hypotheses are proposed and tested. An experiment was conducted with online consumer panel members. Consistent with confirmation bias and familiarity principle, the results supported a hypothesis that …

The Great Radical Dualism: Locating Margaret Fuller’S Feminism In Nathaniel Hawthorne’S Fiction, Renee Michele Vincent

Senior Honors Theses

The purpose of this thesis is to establish a foundation built on the congruencies between Margaret Fuller’s feminist theory and Nathaniel Hawthorne’s fiction, with the aim of addressing two major points: first, the implications of universalizing gender in the context of identity politics; and second, to show how gender universality is challenged within Hawthorne’s fiction and Fuller’s prose. Given that Nathaniel Hawthorne’s characters depict a range of personal variability, the act of synthesizing Margaret Fuller’s feminist theory with Hawthorne’s fiction functions to link the personal with the political. The overall goal of this study is to substantiate both writers within …

Commencement Program 2016 December: College Of Business, The University Of Texas At Arlington

Commencement Programs, Photos, and Video

No abstract provided.

Complex Vegetation Dynamics At The Fire–Grazing–Drought Nexus, Christine H. Bielski

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

The discipline of ecology long ago moved away from viewing systems as static entities where disturbance processes, environmental stochasticity, and spatiotemporal variability play minor roles in determining ecosystem structure and function. Ecological theory continue to develop frameworks and statistical techniques capable of describing the inherent complexity in natural systems. However, in dealing with the complexity in nature, many applied disciplines have yet to adopt such frameworks or statistical techniques. The objective of this study was bridge the gap between ecological theory and application by using complex systems theory to describe grassland vegetation dynamics at the fire-grazing-drought nexus. Chapters 2 and …

Characterization Of Ground Nozzles For Pesticide Applications, Ryan Henry

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Pesticide applications are a common component of crop production systems in the United States (US). For row crop systems (e.g. corn, soybean, or wheat), pesticides are applied by ground, aerial, or chemigation methods. The exact method of pesticide delivery is not universally regulated/ prescribed in the US, and the equipment and application technique are largely defined by the individual applicator. A wide variety of choices and decisions must be made by applicators to result in a successful pesticide application. Examples of these choices include proper active ingredient(s), carrier volume and equipment (e.g. nozzle type, spacing, and operating pressure) selection while …

Retrograde Bullet Migration From Inferior Vena Cava Into Right Common Iliac Vein Following Gunshot: A Case Report, Ibrahim Zahid, Hamza Abdur Rahim Khan, Omar Irfan, Benish Fatima,, Maha Tahir, Muhammad Tariq, Fazal Wahab Khan, Saulat H. Fatimi

Department of Surgery Docs

Abstract

Bullet embolization cases are rare and even rarer are its retrograde migration in the veins. We report the case of a 14 year old male with a gunshot wound to the left side of his chest. CT scan revealed bilateral haemothorax and foreign body in the right common iliac vein. The patient was immediately taken to the operating theatre and median sternotomy performed. Bullet entry tear was found in the inferior vena cava however, the bullet was found lodged in the right common iliac vein and slipped down against the flow of blood. The bullet was left in situ …

Has The Usage Of Precision Agriculture Technologies Actually Led To Increased Profits For Nebraska Producers?, Michael H. Castle

Department of Agricultural Economics: Dissertations, Theses, and Student Research

An ever-increasing global demand for food, coupled with increasingly volatile commodity prices have charged producers with the task of becoming more efficient. As such, technologies aimed at producing more with less are continually being developed and marketed to producers. However, whether or not these expensive new technologies have resulted in improved profitability is still unknown, as the vast majority of studies showing their impact on profitability have been performed using hypothetical farms and simulations. These studies have shown the potential for increases in profitability from use, but their impact in the real world is still uncertain.

This project uses various …

Principals’ Perspectives On The Roles And Skills Of School Psychologists, Jill Mccaslin-Timmons

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Despite decades of literature on how school psychologists could be utilized to better meet needs in school, the way a school psychologist is used still varies and schools still admit that they have unmet needs. Teachers and administrators ask for more staff to help support student needs while taxpayers want to know why more staff are needed. The purpose of this study was to develop an understanding of principal perspectives on the roles and skills of school psychologists in order to better understand why roles vary, what barriers exist and what can be done to help both school psychologists and …

The Effects Of Active Learning Technology On Instructors’ Practices And Students’ Engagement And Grades: A Mixed Methods Study, Jeremy C. Van Hof

College of Education and Human Sciences: Dissertations, Theses, and Student Research

Partly in response to university teachers’ changing pedagogies marked by flipping instruction, lecture capture technologies are evolving into active learning systems. Little published research exists on the effects of active learning technology on either teachers or students. This two-phase sequential explanatory mixed methods study details the effects that active learning systems have on instructor practices and on student grades and engagement. Phase one combined quantitative data collection with instructor interviews. Phase one findings show higher student engagement levels correlate with the use of the active learning system only in the presence of very specific, flipped classroom practices. Phase two, a …

Place Matters? Place And Legislative Behavior In Nebraska, Melissa Lee Trueblood

Department of Political Science: Dissertations, Theses, and Student Research

The dissertation is a three-part analysis of the impact of place and place attachment on legislative behavior in the 2011-2012 session of the Nebraska Unicameral. The first analysis explores whether place or type of legislative district has an effect on roll-call voting. In the second analysis, the dissertation analyzes the relationship between place attachment (defined as the emotional bond between a person and a place) and roll-call voting. Finally, in the third analysis, the dissertation investigates through content analysis how often senators refer to their place attachment, and then, it examines the link between geographic scale of place attachment and …

Can International Criminal Law Deter Rebel Groups? The Case Of Uganda, The Lord's Resistance Army, And The International Criminal Court, Julia Reilly

Department of Political Science: Dissertations, Theses, and Student Research

How does a state’s commitment to international criminal accountability mechanisms affect the tactics of rebel groups fighting against it? I examine the conflict between Uganda and the Lord’s Resistance Army, spanning four phases from 1996 until 2015, and parse out whether Uganda’s stance on the Rome Statute and the International Criminal Court affected the LRA’s propensity to target civilians. I use descriptive statistics of civilian and military casualties and qualitative case studies, drawing largely on newspaper and NGO reports of events in the conflict. I find that the affect of Uganda’s signaling on justice on the LRA’s civilian targeting is …

Exploration Of Student Biodiversity Knowledge And Decision-Making For A Wildlife Conservation Socioscientific Issue, Ashley R. Alred

School of Natural Resources: Dissertations, Theses, and Student Research

Global biodiversity, a foundation for ecosystem function, is diminishing at a rate unprecedented in the last 50 years. Biodiversity loss and ecosystem services deterioration is linked to increased food insecurity, reduced water quality and availability, decreased energy security, higher economic losses and human suffering (Millennium Ecosystem Assessment, 2005). Consequently, educators should invest in supporting students in their development of ecological understanding and formal decision-making skills so they are equipped with meaningful tools they can use as scientifically literate citizens. To contribute to that mission, this study seeks to explore student 1) comprehension and explanation of biodiversity concepts and 2) decision-making …

College And University Sustainability Officers’ Experiences With Green Office Programs: A Qualitative Investigation, Logan Lamb

School of Natural Resources: Dissertations, Theses, and Student Research

The number of sustainability programs in higher education continues to increase. Green office programs have become a cornerstone of sustainability programming on college and university campuses across the country. This exploratory qualitative study involves college and university sustainability officers and investigates their experiences changing behaviors through green office programs. The goal of this study was to provide insight into green office programs. Two side-by-side studies were conducted to provide a detailed analysis of green office programs at both small and large institutions of higher education. Eleven major themes emerged from the study. Six themes emerged from the qualitative analysis of …

Wellbeing And Data Quality In The American Time Use Survey (Atus) From A Total Survey Error Perspective, Ana Lucía Córdova Cazar

Survey Research and Methodology Program: Dissertations, Theses, and Student Research

In this dissertation, I seek to develop a tool for the enhancement of time-use and wellbeing measures from a total survey error perspective. In particular, I evaluate the quality of the time use data produced in the American Time Use Survey (ATUS), by exploring its indicators and identifying its main predictors, including interview rapport. Results from these analyses are then used to evaluate the extent to which certain variables correlate, as predicted, with expected levels of wellbeing.

The first specific objective was to investigate the data quality of the 2010 ATUS by constructing a data quality index. In my dissertation, …

Moving Towards Harmonization Of The Food Safety Standards: Role Of The Tpp And Ttip Agreements, Ksenia A. Petrovets

Journal of Food Law & Policy

We are now less dependent on locally available food resources that we have ever been. The continuing industrialization of food production, the advancement in technologies and the rapid development of supply chains granted us the luxury of immediate access to a variety of products originating from local supermarkets all over the world. This, along with the greater level of food production industrialization, inevitably comes the rise of related food safety risks. Because of the enlargement of producing operations, an emerging safety threat in one place may result in a foodborne illness outbreak thousands of miles away from its place of …

Self-Reported Sleep Apnea And Dementia Risk: Findings From The Prevention Of Alzheimer's Disease With Vitamin E And Selenium Trial, Xiuhua Ding, Richard J. Kryscio, Joshua Turner, Gregory A. Jicha, Gregory E. Cooper, Allison M. Caban-Holt, Frederick A. Schmitt, Erin L. Abner

Sanders-Brown Center on Aging Faculty Publications

OBJECTIVES: To investigate the association between baseline sleep apnea and risk of incident dementia in the Prevention of Alzheimer's Disease with Vitamin E and Selenium (PREADViSE) study and to explore whether the association depends on apolipoprotein E (APOE) ɛ4 allele status.

DESIGN: Secondary analysis based on data collected during PREADViSE.

SETTING: Participants were assessed at 128 local clinical study sites during the clinical trial phase and later were followed by telephone from a centralized location.

PARTICIPANTS: Men enrolled in PREADViSE (without dementia or other active neurological conditions that affect cognition such as major psychiatric disorders, including depression; N = …

Current Trends In Psychological And Educational Approaches For Training And Teaching Students With Autism In California, Trisha Sugita

Education Faculty Articles and Research

Within the United States, Autism Spectrum Disorder (ASD) has seen a dramatic increase over the past twenty years. As the prevalence rate of ASD increases, an increased need for expertise in the field of education has become apparent. Psychological and educational practices for training and teaching students with ASD continue to evolve in California however, a significant gap between theory and practice remains. This article provides a historical perspective of ASD and its prevalence rates. In addition, this article examines the current shifts in teacher training and provides an overview of evidence-based strategies to support students with ASD.

A Dollar A Day: Child Sponsorship And The Marketization Of Human Development, Taylor Hallett

Capstone Collection

Child sponsorship as a method of international development offers child sponsors a personal connection to the process of alleviating poverty in the global South. As a form of human development, child sponsorship is constituted by neoliberal principles of marketization and social entrepreneurship. How does child sponsorship, in this context, require us to rethink the ethics of international development in light of ongoing debates about neoliberalism? In this research, I argue that child sponsorship reifies the binary of the “developed” and “undeveloped” worlds. Through undertaking a content analysis of three organizations (Compassion International, World Vision, and UNICEF) and applying post-structural critique …

Medication Nonadherence, Health Care Utilization, And Safemed Care Transitions Model Impact In Super-Utilizers, Satya Surbhi

Theses and Dissertations (ETD)

BACKGROUND: Super-utilizers are individuals with disproportionately high inpatient and emergency department (ED) use, and mostly have multiple chronic conditions and use multiple concurrent medications. They place a substantial burden on the U.S. healthcare system and have become the focus of policy initiatives aimed at reducing their disproportionate inpatient and ED use. Medication management is critical for these patients since nonadherence to essential chronic medications is associated with poor health outcomes, and higher health care utilization and costs. OBJECTIVES: This dissertation employed a three empirical research papers approach to study the following aims: (1) the prevalence and patterns of medication nonadherence …

Navigation Paths To Adoption Through The Alaska Foster Care System: A Resource Guide For Potential Adoptive Parents, Tashina Duttle

Student Projects for Graduate Degrees

Alaska has a higher than national average rate of adoption from foster care. While just over 20% of children in foster care nationally are discharged from state custody through adoption Alaska has nearly 30% of foster children discharged from state custody through adoption. There are a number of programs and resources available for foster parents and families interested in adopting through foster care in Alaska. However, there lacks a comprehensive single-point reference guide to explore the various paths. This research was conducted to identify resources available for families interested in learning about paths to adopt from foster care in Alaska …

Reexamining Chronic Toxoplasma Gondii Infection: Surprising Activity For A "Dormant" Parasite, Anthony P. Sinai, Elizabeth A. Watts, Animesh Dhara, Robert D. Murphy, Matthew S. Gentry, Abhijit R. Patwardhan

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Purpose of Review

Despite over a third of the world’s population being chronically infected with Toxoplasma gondii, little is known about this largely asymptomatic phase of infection. This stage is mediated in vivo by bradyzoites within tissue cysts. The absence of overt symptoms has been attributed to the dormancy of bradyzoites. In this review, we reexamine the conventional view of chronic toxoplasmosis in light of emerging evidence challenging both the nature of dormancy and the consequences of infection in the CNS.

Recent Findings

New and emerging data reveal a previously unrecognized level of physiological and replicative capacity of bradyzoites …

Warfarin Dosing And Time Required To Reach Therapeutic International Normalized Ratio In Patients With Hypercoagulable Conditions, Pushpinderdeep Kahlon, Shahzaib Nabi, Adeel Arshad, Absia Jabbar, Ali Haythem

Hematology/Oncology Articles

OBJECTIVE: The purpose of this study was to analyze the difference in duration of anticoagulation and dose of warfarin required to reach a therapeutic international normalized ratio [(INR) of 2 to 3] in patients with hypercoagulable conditions as compared to controls. To our knowledge, this study is the first in the literature to delineate such a difference.

MATERIALS AND METHODS: A retrospective chart review was performed in a tertiary care hospital. The total study population was 622. Cases (n=125) were patients with a diagnosis of a hypercoagulable syndrome who developed venous thromboembolism. Controls (n=497) were patients with a diagnosis of …

Comparing The Administration Of University Cooperative Extensions In The United States: A Case Analysis, Fatma Nasoz, Robert E. Lang, William E. Brown Jr.

Lincy Institute Reports and Briefs

For more than a century, cooperative extensions and the land-grant universities have translated and extended research-based knowledge and provided non-formal higher education to their communities. Today, more than 80% of the nation’s population are living in urban areas (The World Bank, 2015). Challenges facing diverse populations require cooperative extensions to collaborate and form partnerships to leverage resources and expertise. This brief explores the nation’s Cooperative Extension System, in particular the university cooperative extensions run by 1862 Land-Grant Universities. Researchers developed an intrinsic case study design to examine cooperative extensions in 15 states and interviewed leaders of the cooperative extensions to …

Latinos, Labor Markets, And The Economic Recovery In Nevada, John Tuman

Brookings Mountain West Publications

During the past six years, Nevada’s economy has recovered. Nevertheless, there has been little research examining how different groups of workers fared during the recovery period. This study fills this gap by analyzing labor market conditions for Latinos throughout the state’s economic recovery.

Social Media: Enhancing The U.S. Military’S Communication With Its Target Audience, Lloyd Eldon Bedford

Dissertations - ALL

The purpose of this qualitative research analysis is to highlight the key changes over the last decade that influenced the U.S. Military to redirect its efforts of ignoring social media, to make it one of its major contributing asset to effective communication. I will examine my findings by answering the following questions to prove or deny that social media has enhanced the U.S. Military’s communication with its target audience. The first question is-Why did the U.S. Military change its strategy on using social media to manage communication? I am aiming to find out who or what events influenced this change …

Pain-Related Anxiety As A Predictor Of Early Lapse And Relapse To Cigarette Smoking, Lisa Renee Larowe

Dissertations - ALL

Pain-related anxiety has been positively associated with tobacco dependence, smoking motives, self-reported barriers to smoking cessation, and expectancies for negative affect reduction via smoking. Although emerging research suggests that pain-related anxiety may play a role in the maintenance of tobacco dependence, no previous work has examined pain-related anxiety as a predictor of smoking cessation outcomes. The goal of the current study was to test the hypothesis that pain-related anxiety would predict early lapse and relapse to cigarette smoking among a sample of 55 daily tobacco smokers who participated in an unaided cessation attempt (i.e., without psychosocial or pharmacological intervention). Pain-related …

Enhancing Engagement For Individuals With Physical Or Cognitive Decline Through The Use Of Multisensory Activities, Jodi Taylor

Dissertations - ALL

Traditional care models typically have a pre- schedule list of activities for elders to engage in, for the purpose of leisure, enjoyments and fun. However, there are questions remaining about the long term benefits of activities and how many residents participate. “RenewedMe” is a service design project with the goal of “Enhancing engagement in individuals with cognitive or physical decline through multi-sensory activities. This project was inspired by the Montessori method principles of education that foster development, engagement and relationships through developmentally appropriate activities. My approach was to create an “environment” that fosters/sustains individualism, builds confidence and sensorial input and …