Digital Commons Network^™

The Immunomodulatory Role Of Adjuvants In Vaccines Formulated With The Recombinant Antigens Ov-103 And Ov-Ral-2 Against Onchocerca Volvulus In Mice., Jessica A. Hess Ligas, Bin Zhan, April R. Torigian, John B. Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J. Hotez, Thomas R. Klei, Sara Lustigman, David Abraham

Department of Microbiology and Immunology Faculty Papers

BACKGROUND: In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical tool for the ultimate elimination of this infection. Previous studies have demonstrated that immunization of mice with Ov-103 and Ov-RAL-2, when formulated with alum, induced protective immunity. It was hypothesized that the levels of protective immunity induced with the two recombinant antigens formulated with alum would be improved by formulation with other adjuvants known to enhance different types …

Conservation Genetics And Mark-Recapture Monitoring Of The Rare Pigeon Mountain Salamander (Plethodon Petraeus) Within A Highly Restricted Range, Kate Donlon

Master of Science in Integrative Biology Theses

Globally, amphibian species are experiencing declines at an alarming rate largely due to habitat loss, disease and climate change. Species with limited ranges are at an elevated risk of a significant decline in population numbers and extinction because of the inability to avoid and recover from these impacts. Long-term management plans are critical for conservation of species with small ranges; however, the knowledge required to develop effective plans is absent from the literature for many species. One such species is the Pigeon Mountain Salamander. The distribution of the Pigeon Mountain Salamander, Plethodon petraeus, is restricted to roughly 17 kilometers …

How The Magnitude Of Prey Genetic Variation Alters Predator-Prey Eco-Evolutionary Dynamics, Michael H. Cortez

Mathematics and Statistics Faculty Publications

Evolution can alter the stability and dynamics of ecological communities; for example, prey evolution can drive cyclic dynamics in predator-prey systems that are not possible in the absence of evolution. However, it is unclear how the magnitude of additive genetic variation in the evolving species mediates those effects. In this study, I explore how the magnitude of prey additive genetic variation determines what effects prey evolution has on the dynamics and stability of predator-prey systems. I use linear stability analysis to decompose the stability of a general eco-evolutionary predator-prey model into components representing the stabilities of the ecological and evolutionary …

Development Of A Decentralized And Off-Grid Anaerobic Membrane Bioreactor (Anmbr) For Urban Sanitation In Developing Countries, Robert Alonso Bair

USF Tampa Graduate Theses and Dissertations

Urbanization has led to rapid and uncontrolled growth of informal housing settlements in many developing countries. As most slum growth is unplanned, these areas tend to lack basic infrastructure including sanitation. The high user rates, lack of water and electricity infrastructure, space limitations, and scant financial resources make sanitation provision a major challenge in slums. As most decentralized sanitation technologies fail when applied in these environments, better technologies need to be developed that cater to the specific needs of slum dwellers. One promising technology, the membrane bioreactor (MBR) is routinely used in developed countries when a compact and resilient treatment …

Works By Uab Department Of Art And Art History Students, Faculty On Exhibition At Lowe Mill In Huntsville, Staff

Browse All News

No abstract provided.

My Orgasms Cannot Be Traded Off Against Others’ Agony, Stevan Harnad

Animal Sentience

Only I can calculate my own welfare as net pleasure minus pain. No one else can do that calculation for me – nor for a population, and especially not averaging across some individuals’ pleasure and other individuals’ pain. Pain and pleasure are incommensurable and only pain matters morally. To maximize welfare is to minimize pain.

In Praise Of Fishes: Précis Of What A Fish Knows (Balcombe 2016), Jonathan Balcombe

Animal Sentience

Our relationship to fishes in the modern era is deeply problematic. We kill and consume more of them than any other group of vertebrates. At the same time, advances in our knowledge of fishes and their capabilities are gaining speed. Fish species diversity exceeds that of all other vertebrates combined, with a wide range of sensory adaptations, some of them (e.g., geomagnetism, water pressure and movement detection, and communication via electricity) alien to our own sensory experience. The evidence for pain in fishes (despite persistent detractors) is strongly supported by anatomical, physiological and behavioral studies. It is likely that fishes …

Sentience As Moral Consideration And Disvalue In Nature, Daniel Dorado

Animal Sentience

In recent work Ng assumes that it is good to engage in activities aimed at promoting ecosystem conservation. The only way Ng can derive this from the axiology he assumes (the view that wellbeing is the only intrinsically valuable or disvaluable thing) would be to assume that ecosystem conservation would benefit the individuals involved. This can be so as long as value prevails over disvalue in the target environments. Ng seems to assume this is indeed the case, but he does not explain why, and it is a claim that goes against the conclusions he has argued for previously (Ng …

Developing Civic Literacy And Efficacy: Insights Gleaned Through The Implementation Of Project Citizen, Lori A. Morgan

i.e.: inquiry in education

Concern exists regarding civic education and involvement among youth in the United States. Where civic education is still given priority, instructional methods do not necessarily focus on the application of the knowledge gained in real and meaningful ways, which research has shown is critical to develop civic literacy and efficacy. This study provides analysis of Project Citizen, a curricular program shown to promote civic literacy and efficacy, in an effort to identify which activities and instructional practices most influenced the civic literacy and efficacy development, and allows student voice regarding their feelings of how the project influenced their civic literacy …

Inalienable Rights And Pluralism In Animal Advocacy, Beril Sözmen

Animal Sentience

I comment on two of Ng’s suggestions. There is a lack of support for his suggestion that some experiments on individual animals will be useful for future success, so they should be permitted. I also question his recommendation that animal advocacy should focus on farmed animals first and wild animals later. The lack of solid support for why this would be a more effective strategy leads me to suggest a more pluralistic support of a variety of types of advocacy.

The Grounds For Animal Subjectivity And Intersubjectivity, Timothy P. Racine

Animal Sentience

Harnad (2016) presents an engaging and persuasive argument that stakes out the aims and domain of the fledgling journal, Animal Sentience. As an inaugural editorial, it does this job masterfully, but it does so from a perspective that tends to treat mental states in an overly general manner and that makes hard distinctions between mental and behavioral phenomena. I argue that when it comes to animal minds, it might be more helpful to think of mental concepts in a more piecemeal way that also retains the intrinsic relation between mind and behavior.

Effect Of Bacteria Isolates In Powdery Mildew Control In Flowering Dogwoods (Cornus Florida L.), Margaret T. Mmbaga, Frank A. Mrema, Lucas Mackasmiel, Emily Rotich

Agricultural and Environmental Sciences Faculty Research

Five bacterial isolates collected from dogwood leaves were evaluated for powdery mildew control in shadehouse and greenhouse environments by using foliar sprays and/or root drenching. Two isolates displayed superior bioactivity and suppressed powdery mildew similar to conventional fungicide thiophanate methyl (Cleary’s 3336F®). The two bacteria disrupted powdery mildew spore germination and ruptured spore membranes causing spore lyses. Bacterial filtrates without bacterial cells were also effective in suppressing powdery mildew and disrupting spore germination and suggested the involvement of secondary metabolites. The two biocontrol agents (BCAs) colonized roots endophytically and promoted plant growth.

07-06-2016 Swosu Biology Students Participate In Experiential Learning Through Summer Research, Southwestern Oklahoma State University

THE BARK ARCHIVE 2016

Fifteen students from the Department of Biological Sciences at Southwestern Oklahoma State University in Weatherford are engaged in making key discoveries through research this summer.

Effects Of Neonicotinoid Pesticide Exposure On Human Health: A Systematic Review., Andria M Cimino, Abee L Boyles, Kristina A Thayer, Melissa J. Perry

Environmental and Occupational Health Faculty Publications

BACKGROUND: Numerous studies have identified detectable levels of neonicotinoids (neonics) in the environment, adverse effects of neonics in many species including mammals, and pathways through which human exposure to neonics could occur, yet little is known about the human health effects of neonic exposure.

OBJECTIVE: This systematic review sought to identify human population studies on the health effects of neonics.

METHODS: Studies published in English between 2005 and 2015 were searched using PubMed, Scopus, and Web of Science databases. No restrictions were placed on the type of health outcome assessed. Risk of bias was assessed using guidance developed by the …

"Womyn's Words" Collection Of Pat Ditto : A Collection Guide, Nelson Poynter Memorial Library. Special Collections And University Archives., James Anthony Schnur, Phillip Sroka, Pat Ditto, Women's Energy Bank

Special Collections and University Archives Legacy Finding Aids: All Items

Womyn’s Words was a monthly periodical published by the Women’s Energy Bank, Inc. that began in 1983. Pat Ditto and other editors and contributors to this publication devoted their efforts to the St. Petersburg and Tampa Bay area in support of the local LGBTQ+ community. Although they primarily advocated for the empowerment and civil rights of women, they also spent a significant amount of time supporting political causes that would benefit the gay community as a whole. Significantly, Womyn’s Words, as early as 1996, was promoting intersectional awareness with their “Afro-Centric Series.” A large portion of their publications was used …

Bibliography Of Secondary Sources On The History Of Dermatology, Sarah Brenner, Md (Editor), Lawrence Parish, Md, Michael J. Lavery, Mb Bch Bao; Mrcp, Andrzej Grzybowski, Md, Phd, Jennifer L. Parish, Md, Daniel H. Parish, Md, Jd

Department of Dermatology and Cutaneous Biology Faculty Papers

Introduction

A bibliographic record on the history of dermatology has been a project that started over 4 decades ago. It is a collection of all forms of history, ranging from dermatologic conditions, to famous dermatologists and physicians who have advanced the field of both dermatology and medicine, to the different countries that promoted the development of scientists, researchers and physicians alike.

It was decided that the bibliographic record would encompass journals, books and a compilation of obituaries. A pertinent question is whether a manually created bibliographic project is still warranted in the 21^st century. In short, yes. While Index …

Divinity Students Become First Gwu Group To Study In Cuba, Office Of University Communications

Gardner-Webb NewsCenter Archive

Seven students from Gardner-Webb University made history in May as the first group from the School of Divinity to travel and study in Cuba. Led by Dr. Hebert Palomino, associate professor of pastoral care and counseling, the group visited several places, including the Baptist seminary in Santiago de Cuba, where Palomino helped to establish a counseling program. “The highlight for me was the opportunity to attend services in different churches,” Rowena Casino, of Boiling Springs, N.C., shared.

Emu Today, July 6, 2016, Eastern Michigan University

EMU Today

No abstract provided.

Anachronisme, Rebuts Et Survivances Dans Les Escaliers De Chambord Et Le Dernier Royaume De Pascal Quignard, Etienne Lussier

Dissertations and Theses

This thesis investigates the particular conception of time developed by Pascal Quignard in his series Dernier Royaume and his novel Les escaliers de Chambord. We argue that this conception of time, which Quignard refers to as Le Jadis, operates through an anachronistic method based on a semiotic apparatus of waste, or rejects. The argument is presented in three different chapters. The first chapter uses the work of Jacques Rancière and Georges Didi-Huberman to show the way in which the concept of anachronism embraces a temporality that blurs the lines between past, present, and future and creates openings to …

Habitat Patch Size Alters The Importance Of Dispersal For Species Diversity In An Experimental Freshwater Community, Matthew Schuler, Jonathan M. Chase

Department of Biology Faculty Scholarship and Creative Works

Increased dispersal of individuals among discrete habitat patches should increase the average number of species present in each local habitat patch. However, experimental studies have found variable effects of dispersal on local species richness. Priority effects, predators, and habitat heterogeneity have been proposed as mechanisms that limit the effect of dispersal on species richness. However, the size of a habitat patch could affect how dispersal regulates the number of species able to persist. We investigated whether habitat size interacted with dispersal rate to affect the number of species present in local habitats. We hypothesized that increased dispersal rates would positively …

Dasatinib-Loaded Albumin Nanoparticles Possess Diminished Endothelial Cell Barrier Disruption And Retain Potent Anti-Leukemia Cell Activity, Chunling Dong, Bo Li, Zhenyu Li, Sreerama Shetty, Jian Fu

Internal Medicine Faculty Publications

Dasatinib (DAS), a second-generation tyrosine kinase inhibitor, is highly effective in treating chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia. However, its clinical use is limited due to serious adverse effects. DAS can disrupt endothelial barrier integrity and increase endothelial permeability which may cause peripheral edema and pleural effusion. Albumin nanoparticles (NPs) as a drug carrier may serve as a useful tool for cell-selective drug delivery to reduce DAS-induced endothelial hyperpermeability and maintain endothelial barrier integrity. In this study, we reported that DAS-loaded NPs exhibited potent anti-leukemia efficacy as DAS alone. Importantly, albumin NPs as a drug carrier markedly …

Cuba: "Trip Of A Lifetime", Megan Savoie

UNH Today Archive

No abstract provided.

3d Map Of The Human Corneal Endothelial Cell, Zhiguo He, Fabien Forest, Philippe Gain, Damien Rageade, Aurélien Bernard, Sophie Acquart, Michel Peoc'h, Dennis M. Defoe, Gilles Thuret

ETSU Faculty Works

Corneal endothelial cells (CECs) are terminally differentiated cells, specialized in regulating corneal hydration and transparency. They are highly polarized flat cells that separate the cornea from the aqueous humor. Their apical surface, in contact with aqueous humor is hexagonal, whereas their basal surface is irregular. We characterized the structure of human CECs in 3D using confocal microscopy of immunostained whole corneas in which cells and their interrelationships remain intact. Hexagonality of the apical surface was maintained by the interaction between tight junctions and a submembraneous network of actomyosin, braced like a drum. Lateral membranes, which support enzymatic pumps, presented complex …

The Murray Ledger And Times, July 6, 2016, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Biomarkers Of Orthodontic Tooth Movement With Fixed Appliances And Vibration Device: A Randomized Clinical Trial, Marie-Claude Chouinard

Master's Theses

Biomarkers of orthodontic tooth movement with fixed appliances and vibration device: A randomized clinical trial

Marie-Claude Chouinard D.M.D.

ABSTRACT

Background: On average, comprehensive orthodontic treatments last approximately 21-27 months in non-extraction cases and 25-35 months when teeth elected for extraction. Longer treatment times have been associated with multiple detrimental effects such as white spot lesions, root resorption, gingival inflammation and dental caries. Recently, some evidence has shown that the application of mechanical vibration to the dentition can increase the rate of tooth movement. However, the biological mechanism underlying this effect is not clearly understood. The aims of this study were …

Biofouling Management In The Pacific Northwest And Predation On Native Versus Non-Native Ascidians, Erin Suzanne Kincaid

Dissertations and Theses

Marine non-native species threaten economic and environmental health, making it crucial to understand factors that make them successful. Research on these species, therefore, allows for greater preparedness and informed management of biological invasions and increases understanding of elements structuring biological communities. Among the marine non-native species, and particularly the fouling community, non-native ascidians are a taxon of particular concern because they can crowd out native benthic species and smother mariculture products. This thesis addresses management for ascidians and other fouling organisms and includes research on the invasiveness of this taxon in addition to the invasibility of recipient fouling communities. On …

Where Does The Cetanic Break Take Place? Weakness Of Will In Śāntideva’S Bodhicaryāvatāra, Stephen E. Harris

Comparative Philosophy

This article explores the role of weakness of will (akrasia) in the Indian Buddhist tradition, and in particular within Śāntideva’s Introduction to the Practice of Awakening (Bodhicaryāvatāra). In agreement with Jay Garfield, I argue that there are important differences between Aristotle’s account of akrasia and Buddhist moral psychology. Nevertheless, taking a more expanded conception of weakness of will, as is frequently done in contemporary work, allows us to draw significant connections with the pluralistic account of psychological conflict found in Buddhist texts. I demonstrate this by showing how Amélie Rorty’s expanded treatment of akrasia as including …

Ns-3 Airborne Network Simulation, Evelyn Brown

URI Summer Symposium - Prescott

Airborne networks, consisting of aircraft-to-aircraft and aircraft-to-ground communications, are critical for future aviation information systems and remote Internet access. A major knowledge gap, however, is the reliability and security challenges of airborne networks in such civilian application domains. Field tests and emulations of airborne networks are expensive undertakings and would be better informed by simulation findings. This paper, hence, reports about a study that aims to simulate airborne networks to understand and characterize their performance and risks. We choose ns-3, an open source network simulation tool, to construct and evaluate airborne networks. We implement 3-D mobility models in ns-3 to …

Changing Attitudes Towards Animals In The Wild And Speciesism, Oscar Horta

Animal Sentience

I argue that despite Ng’s claim that we should postpone the defense of those animals that live in the wild, we do have reasons to start spreading concern for them now. We can do it by (i) changing public attitude by heightening awareness of speciesism, by which we will also challenge animal exploitation; and (ii) by disseminating information about the situation of animals in the wild.

Reading Horizons Vol. 55 No. 2

Reading Horizons: A Journal of Literacy and Language Arts

No abstract provided.