Digital Commons Network^™

The Acquisition Of Bare Nominals By Three Populations Of Spanish-English Bilingual Adults, Lauren Elizabeth Miller

Open Access Dissertations

The present study contributes to our understanding of cross-linguistic influence by studying three different groups of Spanish-English speakers’ knowledge of the distribution of definite articles in both of their languages using a battery of tests that require them to draw on different linguistic abilities. These three groups include native English speakers who learned Spanish after adolescence, native Spanish speakers who learned English after adolescence and simultaneous bilinguals who grew up in the United States speaking both English and Spanish from birth. Specifically, this study explores interpretation, production and intuition regarding the acceptability of definite articles in different contexts. Since the …

Intestinal Adaptation To Repeated Exposure Of Flavonoid-Rich Foods: In Vitro And Clinical Data, Bejamin W. Redan

Open Access Dissertations

Interest in application of flavonoids for chronic disease prevention has grown significantly, but the low oral bioavailability of these compounds from acute doses is commonly highlighted as a limitation when considering their biological significance. Still, the impact of broad dietary patterns such as repeated exposure on flavonoid’s absorption, metabolism, and eventual efficacy is critical to consider since evidence suggests that their bioavailability may be enhanced with repeated exposure. To fill this gap in knowledge, this dissertation will focus on three major areas including characterization of flavonoid metabolites, in addition to use of in vitro models and clinical work to test …

The Role Of Mechanical Loading In Chondrocyte Signaling Pathways, Qiaoqiao Wan

Open Access Dissertations

Chondrocytes are a predominant cell type present in articular cartilage, whose integrity is jeopardized in joint degenerative diseases such as osteoarthritis (OA). In the chondrocytes of patients with OA, the elevated levels of inflammatory cytokines such as interleukin 1β (IL1β) and tumor necrosis factor α (TNFα) have been reported. These cytokines contribute to degradation of cartilage matrix by increasing activities of proteolytic enzymes. In addition to their contribution to proteolytic enzymes, these cytokines adversely affect anabolic activity of chondrocytes by inhibiting the production of proteoglycans and type II collagen. Therefore, blocking the action of these cytokines is a potential strategy …

A Comparison Of Plants And Animals In Their Responses To Risk Of Consumption, Richard Karban, John L. Orrock, Evan L. Preisser, Andrew Sih

Biological Sciences Faculty Publications

Both plants and animals reduce their risk of being eaten by detecting and responding to herbivore and predator cues. Plants tend to be less mobile and rely on more local information perceived with widely dispersed and redundant tissues. As such, plants can more easily multi-task. Plants are more tolerant of damage and use damage to their own tissues as reliable cues of risk; plants have a higher threshold before responding to the threat of herbivory. Plants also use diverse cues that include fragments of plant tissue and molecular patterns from herbivores, herbivore feeding, or microbial associates of herbivores. Instead of …

Blood-Tissue Barriers And Autoantibodies In Neurodegenerative Disease Pathogenesis: An Approach To Diagnostics And Disease Mechanism, Eric Luria Goldwaser

Graduate School of Biomedical Sciences Theses and Dissertations

Brain homeostasis can be affected in a number of ways that lead to gross anatomical, cellular, and molecular disturbances giving rise to diseases like Alzheimer’s disease (AD) and related dementias. Unfortunately, the mechanistic pathoetiology of AD’s hallmark features of cerebral amyloid plaque buildup and neuronal death are still disputed. Using human brain AD sections, immunohistochemistry experiments revealed internalized surface proteins, co-localized to an expanded lysosomal compartment. Other stains for amyloid-β1-42 (Aβ42) and various immunoglobulin (Ig) species displayed them leaking out of the cerebrovasculature through a dysfunctional blood-brain barrier (BBB), binding to neurons in the vicinity, and localizing to intracellular vesicles …

Stem Stories, August 2016, Mir Ashfaquzzaman

STEM Stories

Student Profile - Courtney Massey

Molecular Cloning And Expression Of Chitin Deacetylase 1 Gene From The Gills Of Penaeus Monodon (Black Tiger Shrimp), Katreena P. Sarmiento, Vivian A. Panes, Mudjekeewis D. Santos

Biology Faculty Publications

Chitin deacetylases have been identified and studied in several fungi and insects but not in crustaceans. These glycoproteins function in catalyzing the conversion of chitin to chitosan by the hydrolysis of N-acetamido bonds of chitin. Here, for the first time, the full length cDNA of chitin deacetylase (CDA) gene from crustaceans was fully cloned using a partial fragment obtained from a transcriptome database of the gills of black tiger shrimp Penaeus monodon that survived White Spot Syndrome Virus (WSSV) infection employing Rapid Amplification of cDNA Ends (RACE) PCR. The shrimp CDA, named PmCDA1, was further characterized by in silico …

Alumni Journal - Volume 87, Number 2, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Features
10 | An Unexpected Visit
12 | APC 2016 in Review
24 | Medicine, Faith, and Hope

Departments
2 | From the Editor
4 | From the President
6 | From the Dean
7 | The Student Fund
8 | School of Medicine News
42 | AIMS Report
46 | Alumni News
48 | In Memoriam
52 | Historical Snapshot
53 | What's Up Doc?

Extras
3 | New Executive Director
11 | Class Giving Report
49 | Tribute to Lawrence D. Longo '54

2016-08 Library Impact Statement For Avs 344 Methods In Applied Animal Behavior, Michael Cerbo

Library Impact Statements

Library Impact Statement submitted in response to new course proposal for AVS 344 Methods in Applied Animal Behavior. No new library resources were required to support this class. Responding library faculty: Michael Cerbo. Requesting faculty: Justin Richards and Anthony Mallilo.

Influence Of Resource Availability On Juniperus Virginiana Expansion In A Forest–Prairie Ecotone, A. C. Ganguli, D. M. Engle, P. M. Mayer, L. F. Salo

United States Environmental Protection Agency: Publications

Woody plant expansion into grasslands and savannas is a global concern. Rapid expansion of Juniperus virginiana, a tree native to North America, has profound ecological consequences. We used transplanted J. virginiana seedlings to investigate the role of resource availability on J. virginiana expansion following the removal of fire, the factor historically limiting range expansion of this fire-intolerant species. We evaluated J. virginiana seedling survival and seedling growth, two important phases in woody plant expansion, relative to two below ground resource factors, plant-available soil water (soil clay content, an index of plant-available soil water) and plant-available nitrogen (PAN), and an above …

The Role Of Organic Matter In The Fate And Transport Of Antibiotic Resistance, Metals, And Nutrients In The Karst Of Northwest Arkansas, Victor Lee Roland Ii

Graduate Theses and Dissertations

Organic matter (OM) in the environment acts as a nutrient, but may also act as a transport vector for harmful chemical compounds and bacteria. Acetate is a labile form of OM produced during fermentation in anaerobic lagoons used to store animal fecal-waste from concentrated animal feeding operations (CAFOs). Dry and liquid fertilizers from CAFOs pose a threat to groundwater by introducing excessive amounts of nutrients (e.g. OM, nitrate and ammonia), metals, and antibiotic compounds. In the epikarst of Northern Arkansas in the Buffalo River watershed additional input of labile dissolved organic carbon (DOC) from liquid CAFO waste-fertilizers was hypothesized to …

Agro-Climatic Change, Crop Production And Mitigation Strategies-Case Studies In Arkansas, Usa And Kenya, John Westley Magugu

Graduate Theses and Dissertations

Although climate change impacts vary geographically and temporally, studies at local levels are not readily available for stakeholders to better understand how their local communities would be affected and what remedial measures could be more effective in their local contexts. This dissertation has examined climate change and its impacts in two different local contexts: eastern Arkansas in the USA and Nyando in Kenya. The first part of this dissertation develops agro-meteorological indicators and examines the relationship between agro-meteorological indicators and crop yields in eastern Arkansas between 1960 and 2014. Results reveal that temperature based indicators were more strongly correlated to …

Development Of A Fluidic Mixing Nozzle For 3d Bioprinting, Will Hoggatt

Open Access Theses

3D bioprinting is a relatively new and very promising field that uses conventional 3D printing techniques and adapts them to print biological materials that are suited for use with cells. These bioprinters can be used to print cells encapsulated within biological "ink" (bio-ink) to create and customize complex three-dimensional tissues and organs. Our work has focused on developing a new bioprinter nozzle that addresses critical gaps with present-day bioprinters, namely, the lack of standardized, physiologically-relevant biomaterials, and their one nozzle per composition printing capacity. These shortcomings preclude printing a range of cellular and biomaterial compositions (including gradients of cells and …

The Dark Side Of Reactive Attitudes: From Persons To Compatibilism, Mallory A. Parker

Open Access Theses

This thesis contains two independent papers that both address the problems associated with the reactive attitudes. The first paper, presented in Chapter 2, discusses the negativities of the reactive attitudes in debates regarding skepticism about the moral notion of persons. The second paper, presented in Chapter 3, presents the negativities associated with the reactive attitudes in debates concerning compatibilism about moral responsibility. Neither chapter deals solely with presenting the negativities associated with the reactive attitudes. More than present these, both chapters undermine the non-realist or compatibilist philosophical arguments that attempt to save either the moral notion of persons (Chapter 2) …

2016 Summary Report On Institutional Effectiveness, Clemson University

Institutional Effectiveness Reports

No abstract provided.

Clemson Commencement Program, August 2016, Clemson University

Clemson Commencement Programs

No abstract provided.

Multiple Sclerosis Risk Loci And Disease Severity In 7,125 Individuals From 10 Studies., Michaela George, Farren B. S. Briggs, Xiaorong Shao, Milena A. Gianfrancesco, Ingrid Kockum, Hanne F. Harbo, Elisabeth G. Celius, Steffan D. Bos, Anna Hedström, Ling Shen, Allan Bernstein, Lars Alfredsson, Jan Hillert, Tomas Olsson, Nikolaos A. Patsopoulos, Philip L. De Jager, Annette B. Oturai, Helle B. Søndergaard, Finn Sellebjerg, Per S. Sorensen, Refujia Gomez, Stacy J. Caillier, Bruce A. C. Cree, Jorge R. Oksenberg, Stephen L. Hauser, Sandra D'Alfonso, Maurizio A. Leone, Filippo Martinelli Boneschi, Melissa Sorosina, Ingrid Van Der Mei, Bruce V. Taylor, Yuan Zhou, Catherine Schaefer, Lisa F. Barcellos

Global Public Health | Faculty Scholarship

OBJECTIVE: We investigated the association between 52 risk variants identified through genome-wide association studies and disease severity in multiple sclerosis (MS).

METHODS: Ten unique MS case data sets were analyzed. The Multiple Sclerosis Severity Score (MSSS) was calculated using the Expanded Disability Status Scale at study entry and disease duration. MSSS was considered as a continuous variable and as 2 dichotomous variables (median and extreme ends; MSSS of ≤5 vs >5 and MSSS of

RESULTS: A total of 7,125 MS cases were analyzed. The wGRS and GRS were not strongly associated with disease severity after accounting for cohort, sex, age …

The Feasibility Of Using Drones To Count Songbirds, Andrew M. Wilson, Janine M. Barr, Megan E. Zagorski

Environmental Studies Student Conference Presentations

Point and transect counts are the most common bird survey methods, but are subject to biases and accessibility issues. To eliminate some of these biases, we propose attaching a recorder to a consumer-grade quadcopter (Unmanned Aerial Vehicle, or UAV) to estimate songbird populations from audio recordings. We conducted a blind experiment using broadcast recordings to estimate the detection radius of a compact recorder attached to a UAV, and found that the detection radius did not vary significantly when the UAV was flown at elevations of 20, 40 and 60m. We field tested our system by comparing UAV-based bird counts with …

Complex Multidisciplinary Systems Decomposition For Aerospace Vehicle Conceptual Design And Technology Acquisition, Amen Omoragbon

Mechanical and Aerospace Engineering Dissertations - Archive

Although, the Aerospace and Defense (A&D) industry is a significant contributor to the United States’ economy, national prestige and national security, it experiences significant cost and schedule overruns. This problem is related to the differences between technology acquisition assessments and aerospace vehicle conceptual design. Acquisition assessments evaluate broad sets of alternatives with mostly qualitative techniques, while conceptual design tools evaluate narrow set of alternatives with multidisciplinary tools. In order for these two fields to communicate effectively, a common platform for both concerns is desired. This research is an original contribution to a three-part solution to this problem. It discusses the …

The Effects Of Temperature And Relative Humidity On Exposure Of Legacy And Future Technology Hardware, Under Real Data Center Conditions In An Ansi/Isa Classified G2 Environment, Oluwaseun Michael Awe

Mechanical and Aerospace Engineering Dissertations - Archive

It is well established that it is safe to operate information technology (IT) equipment in a G1 classified contaminant severity level when operating within specified ASHRAE recommended and allowable limits in an air-side economizer data center. This is basis for which electronic equipment manufacturers provide warranty for their products. IT equipment manufacturers in the US now requires data centers operators to demonstrate that they meet all the specified conditions consistently before fulfilling warranty equipment failure. This places limitation to where data center utilizing air-side economizer can be located. In order to determine the reliability of electronic hardware in higher severity …

Understanding The Alchemilla Leaf And Its Hydrophobicity, Atul Mohandas Kootathil

Mechanical and Aerospace Engineering Theses - Archive

The Alchemilla leaf has been well known and studied frequently for its hydrophobic ability. However, much difficulty has been met in replicating its microstructure for hydrophobic applications. Also, not much experimental data was found on the behavior of leaf’s microstructure. Gathering information from experimental results may provide new understanding of its wetting properties before attempting to mimetic its wetting behavior. In this research, the focus is to detail the observed solid-water-air interaction on Alchemilla leaf by simulating condensation, evaporation and rainfall conditions, which are the common ways that a plant may interact with water drops in nature. Documenting these observations …

Developing And Validating Energy Models For Indirect And Direct Evaporative Cooling Used In Datacenters, Rajesh Kasukurthy

Mechanical and Aerospace Engineering Theses - Archive

In the present day to day life, Internet of things is everything, i.e., we need internet and telecommunication for almost every task of our life and these require data from data centers. These data centers provide various facilities like data processing, storage, and transmission, and maintenance, operations etc., for performing these tasks, a huge amount of power is consumed by the data center, which in turn generates large amount of heat. As these data centers are to be made operational throughout the year, cooling of data centers is of utmost importance. These cooling systems like air conditioners, economizers and evaporative …

Gold-Nanoparticle-Based Theranostic Agents For Radiotherapy Of Malignant Solid Tumors, Sina Moeendarbari

Material Science and Engineering Dissertations - Archive

Radiation therapy is one of the three major methods of cancer treatment. The fundamental goal of radiotherapy is to deliver high radiation doses to targets while simultaneously minimizing doses to critical structures and healthy normal tissues. The aim of this study is to develop a general, practical, and facile method to prepare nanoscale theranostic agents for more efficacious radiation therapy with less adverse side effects. First, a novel type of gold nanoparticle, hollow Au nanoparticles (HAuNPs) which was synthesized using the unique bubble template synthesis method developed in our lab, are studied in vitro and in vivo to investigate their …

Osteogenic Differentiation In Preosteoblast Mc3t3-E1 Cells Induced By Beta Tricalcium Phosphate Bioglass Composite, Chien-Ning Yao

Material Science and Engineering Theses - Archive

The use of bioactive material from bioceramic and composite components to support bone cell and tissue growth is an interesting area of medical field. Calcium phosphate ceramics are biocompatible and may develop interactions with human living bone tissues. Bioactive calcium phosphates, beta -tricalcium phosphate (β-TCP), have been intensively investigated as the cell scaffold for bone tissue engineering because it is well recognized that they are compatible to natural bone tissue and osteoconductive. In this research we will discuss two types of biomaterial with different kind of composition—(a) a cement type and (b)a scaffold type of biomaterial that can be applied …

Centimeter-Deep Tissue Fluorescence Microscopic Imaging, Bingbing Cheng

Bioengineering Dissertations - Archive

Fluorescence microscopic imaging in centimeter-deep tissue has been highly sought-after for many years because much interesting in vivo micro-information—such as microcirculation, tumor angiogenesis, and cancer metastasis—may deeply locate in tissue. However, it is very challenging because of strong tissue light scattering. This includes: how to confine the fluorescence emission into a small volume to achieve high spatial resolution; how to increase fluorescence emission efficiency to compensate the signal attenuation caused by small emission volume and tissue scattering/absorption; and how to reduce background fluorescence noise and exclusively differentiate signal photons from background photons to increase signal-to-noise ratio (SNR) and sensitivity. Ultrasonic …

Biological Sciences Newsletter - Fall 2016, Department Of Biological Sciences, East Tennessee State University

Biological Sciences Newsletters

No abstract provided.

Molecular Mechanisms Linking Autonomic Dysfunction And Impaired Cardiac Contractility In Critical Illness, Gareth L. Ackland, John Whittle, Andrew Toner, Asif Machhada, Ana Gutierrez Del Arroyo, Alberto Sciuso, Nicholas Jenkins, Alex Dyson, Richard Struthers, J. Robert Sneyd, Gary Minto, Mervyn Singer, Ajay M. Shah, Alexander V. Gourine

More Faculty of Health Research

Objectives: Molecular mechanisms linking autonomic dysfunction with poorer clinical outcomes in critical illness remain unclear. We hypothesized that baroreflex dysfunction alone is sufficient to cause cardiac impairment through neurohormonal activation of (nicotinamide adenine dinucleotide phosphate oxidase dependent) oxidative stress resulting in increased expression of G-protein-coupled receptor kinase 2, a key negative regulator of cardiac function. Design: Laboratory/clinical investigations. Setting: University laboratory/medical centers. Subjects: Adult rats; wild-type/nicotinamide adenine dinucleotide phosphate oxidase subunit-2-deficient mice; elective surgical patients. Interventions: Cardiac performance was assessed by transthoracic echocardiography following experimental baroreflex dysfunction (sino-aortic denervation) in rats and mice. Immunoblots assessed G-protein-coupled receptor recycling proteins expression …

August 2016 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Rio’S 2016 Olympic Golf Course: City’S Last Remaining Ecosystems Left “In The Rough”, Charles Vercillo

University of Miami Inter-American Law Review

The sport of golf returned as an official event at the 2016 Summer Olympics held in Rio de Janeiro following a prolonged absence from the Games. To accommodate golf’s return, the city of Rio endorsed the construction of the Olympic golf course on land adjoining the Marapendi lagoon—land historically known to be ecologically valuable and environmentally protected. With the Games rapidly approaching, the city quickly passed complementary Law 125, stripping this land of its environmental protection, and instead authorizing a golf course as a sustainable use of the land.

Local environmentalists have challenged the legislation and the city’s decision, arguing …

Evaluation Of Food Waste Diversion Potential And Economics Of Using Food Waste Dehydrators, Arindam Dhar

Civil Engineering Theses - Archive

According to US EPA (2013), food waste is the second largest component (14.6%) of MSW composition in the US, preceded only by paper. Apart from the negative environmental impacts of food waste through methane and leachate generation, it also incurs huge cost to landfill them. Hence, food waste diversion from landfills is becoming a major issue in landfills across many US states. Though biological treatment of food waste is a potential alternative for food waste diversion, the existing scale of this type of treatment is very narrow. On-site treatment of food waste is a suitable alternative as it can be …