Digital Commons Network^™

Appraisal Of The Impact Of Aluminosilicate Use On The Health And Performance Of Poultry, Ali Gilani, Hassan Kermanshahi, Abolghasem Golian, Saeed Seifi

Turkish Journal of Veterinary & Animal Sciences

Aluminosilicates are feed additives used for multiple purposes in the poultry industry. Bentonites, zeolites, and kaolins are types of aluminosilicate compounds that appear in the marketplace due to their capabilities as mycotoxin adsorbents and other qualifications. While there are some differences among their efficacies, anecdotal evidence confirms that these additives ameliorate aflatoxicosis and manure ammonia emission, and improve the durability of pelleted diets. Furthermore, these supplements are safe at 0.2%-1% inclusion levels in the commercial diet of broilers and layers and did not have any adverse effects on productive indices, and even promoted birds' performance. Nevertheless, their upper levels, especially …

Computational Tracking Of Shear-Mediated Platelet Interactions With Von Willebrand Factor, Adam Ralph, Martin Somers, Jonathan Cowman, Bruno Voisin, Emma Hogan, Hannah Dunne, Eimear Dunne, Barry Byrne, Nigel Kent, Antonio J. Ricco, Dermot Kenny, Simon Wong

Articles

The imaging of shear-mediated dynamic platelet behavior interacting with surface-immobilized von Willebrand factor (vWF) has tremendous potential in characterizing changes in platelet function for clinical diagnostics purposes. However, the imaging output, a series of images representing platelets adhering and rolling on the surface, poses unique, non-trivial challenges for software algorithms that reconstruct the positional trajectories of platelets. We report on an algorithm that tracks platelets using the output of such flow run experiments, taking into account common artifacts encountered by previously-published methods, and we derive seven key metrics of platelet dynamics that can be used to characterize platelet function. Extensive …

49(1) Front Matter

UBC Law Review

No abstract provided.

The Relaxation Of Representative Standing In Administrative Law: A Side Effect Of Charters Of Rights

UBC Law Review

No abstract provided.

Recasting Our Wild Neighbours: Contesting Legal Otherness In Urban Human-Animal Conflicts

UBC Law Review

No abstract provided.

Faculty Authors & Achievers Bibliography 2016, Luke Vilelle

WRL: Faculty Authors & Achievers Bibliographies

The office of the Vice President for Academic Affairs and the Wyndham Robertson Library congratulate all Hollins faculty who published or presented creative or scholarly works from Fall 2014 through Summer 2016. This bibliography includes a list of those activities.

Expressions, Winter 2016, San Jose State University, College Of The Humanities And The Arts

Expressions (College of Humanities and the Arts)

College of Humanities and the Arts Newsletter, Volume 9

Categorical Perception Of Species In Infancy, Hannah B. White

Theses and Dissertations--Psychology

Although there is a wealth of knowledge on categorization in infancy, there are still many unanswered questions about the nature of category representation in infancy. For example, it is yet unclear whether categories in infancy have well-defined boundaries or what knowledge about species categories young infants have before entering the lab. Using a morphing technique, we linearly altered the proportion of cat versus dog in images and observed how infants reacted to contrasts between pairs of images that either did or did not cross over the categorical boundary. This was done while equating between-category and within-category similarity. Results indicate that …

Validity Of Immediate Post-Concussion Assessment And Cognitive Testing (Impact), Lisa Mason Koehl

Theses and Dissertations--Psychology

Sports concussions have been recognized as significant injuries among young athletes with research demonstrating that return-to-play prior to becoming asymptomatic can have significant repercussions, including risk of sustaining cognitive deficits. In tracking and monitoring concussions during sports seasons, many programs have begun utilizing computerized testing rather than traditional neuropsychological tests to 1) determine baseline scores, 2) track symptoms, and 3) measure cognitive deficits following concussion.

Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is one such instrument. The current study examined ImPACT’s convergent, discriminant, and diagnostic validity by comparing scores from post-concussion athletes (SPORT) to those from non-concussed controls (CONT). SPORT …

Novel Spoxazomicins Derived From Streptomyces Sp. Rm-14−6 Attenuate Ethanol Induced Cytotoxicity In Vitro, Meredith A. Saunders

Theses and Dissertations--Psychology

An estimated 13.9% of Americans currently meet criteria for an alcohol use disorder. Ultimately, chronic alcohol use may result in neurological deficits, with up to 85% of alcoholics exhibiting signs of cognitive decline. However, biochemical and behavioral factors contributing to this decline have remained elusive. Our ongoing research program encompasses a multi-tiered screening of a natural product library and validation process to provide novel information about mechanisms underlying these deficits and to identify novel chemical scaffolds to be exploited in the development of pharmacological treatments for alcohol use disorders in a rodent organotypic hippocampal slice culture mode. Experiment 1 sought …

Deep Brain Stimulation For Parkinson's Disease: An Investigation Of Post-Surgical Self-Regulation And Executive Functioning, Hannah L. Combs

Theses and Dissertations--Psychology

Parkinson’s Disease (PD) is a common neurodegenerative disorder that attacks the basal ganglia and contributes to a range of motor, cognitive, and behavioral impairments (e.g., tremor, rigidity, and executive dysfunction). This dysfunction may contribute to self-regulatory impairment across several domains, including cognitive skills, thought processes, and emotion. Deep Brain Stimulation (DBS) is a neurosurgical procedure that allows for direct and reversible manipulation of brain activity in patients with PD. The procedure is growing in popularity and is commonly used as an adjunct or in some instances an alternative to dopaminometic medications. Preliminary studies suggest mild executive dysfunction follows DBS but …

Adopting The Unesco Ethics Model To Critique Disease Mongering, Barbara Postol

Electronic Theses and Dissertations

The question this dissertation seeks to address is if the process of disease mongering can be ethically assessed. Chapter one provides a broad scope of the ethical challenge of disease mongering, UNESCO model framework, ADHD and PMDD. Chapter two examines disease mongering and its driving forces in detail. Chapter three provides an overview of the UNESCO model framework. Chapter four ethically examines disease mongering in conjunction with Attention Deficit Hyperactivity Disorder (ADHD). Chapter five examines disease mongering in association with Premenstrual Dysphoric Disorder (PMDD). Chapter six concludes that examined through the UNESCO model ethical framework disease mongering is occurring for …

The Effect Of Victim Religion On Juror Perceptions Of Hate Crimes, Casey Magyarics

Theses and Dissertations--Psychology

The present study investigated mock juror perceptions of hate crimes in the courtroom, specifically whether a victim’s religion (Atheist, Christian, Jewish, or Muslim) influenced the likelihood that a mock juror would render a hate crime verdict. I employed a mock juror methodology where participants read an assault trial summary, rendered a verdict, and answered a series of rating questions about the victim and defendant. Two theoretical explanations were proposed to explain the main effect of victim religion on participant verdict decisions; that participants would be most likely to render a guilty verdict when the victim is considered an in-group member …

The Paradox Of Clean Food And The Food Safety Modernization Act: Understanding The Fda's Preventive Controls For Human Food Rule, Melissa M. Card

SMU Science and Technology Law Review

No abstract provided.

Contours Of Gmo Regulation And Labeling, Joanna K. Sax

SMU Science and Technology Law Review

No abstract provided.

Glimpses Of Marshall In The Military, Kevin C. Walsh

Scholarly Articles

Before President John Adams appointed him as Chief Justice of the United States in 1801, John Marshall was a soldier, a state legislator, a federal legislator, an envoy to France, and the Secretary of State. He also maintained a thriving practice in Virginia and federal courts, occasionally teaming up with political rival and personal friend Patrick Henry. Forty-five years old at the time of his appointment to the Supreme Court, Marshall has been serving his state and his country for a quarter century before he took judicial office. Marshall is an exemplar of professional excellence for all lawyers and judges. …

The Identification Of The Direct And Indirect Pathways Through Which Leptin Facilitates Synaptic Plasticity In The Hippocampus, Catherine Van Doorn

Theses and Dissertations

Leptin, a peptide synthesized by adipocytes in the periphery, has been shown to play significant roles in feeding and energy expenditure mediated by the hypothalamus. Growing evidence supports the role of leptin in influencing synaptic plasticity in the hippocampus in that leptin dose-dependently enhances LTP, alters morphology and neurogenesis, facilitates spatial learning and memory, as well as memory retention. Models of leptin deficiency and resistance have further supported the importance of leptin in synaptic plasticity by exhibiting deficits in electrophysiological, morphological and behavioral tests that are improved after leptin restoration. The effects of leptin when applied directly into the hippocampus …

Neural And Behavioral Correlates Of Planning During Vocal Motor Control, Stacey Jean Sangtian

Theses and Dissertations

Speech is a goal-directed movement developed to serve the purpose of human communication. During speech, the brain simultaneously coordinates complex motor behavior and sensory information for planning, execution and online monitoring for error correction in order to ensure accurate delivery of the vocal messages. Models of speech production and voice motor control have adapted the principles of the internal forward model to explain that speech sound production is controlled by comparison of internal predictions with sensory feedback. Growing evidence from studies conducted in speech and limb motor movement indicate that these sensory predictions and responsive commands are loaded in anticipation …

Role Of Altered Gut Microbiota In Tumor Development, Mucus Production And Inflammation In Apc Min/+ Mouse Model, Kamaljeet Kaur

Theses and Dissertations

The microbiome forms an integral part of the gut microenvironment. Once ignored, the topic has gained momentum in research during the past decade, where studies have strongly suggested the association of microbiota with health and a misbalance thereof, to many disease conditions ranging from inflammation and colitis to diabetes, obesity and colon cancer. The Human Microbiome Project (HMP, NIH common fund - 2008) has used a variety of high throughput analyses in order to study gut microbiota in health. The consortium has so far been able to isolate and characterize more than 1,300 reference bacterial strains from the human body. …

Modern Estimation Problems In Group Testing, Md Shamim Sarker

Theses and Dissertations

In the simplest form of group testing, pools are formed by compositing a fixed number of individual specimens (e.g., blood, urine, swab, etc.) and then the pools are tested for a binary characteristic, such as presence or absence of a disease. Group testing is commonly used to screen for a variety of sexually transmitted diseases in epidemiological applications where the main goal is to increase testing efficiency. In this dissertation, we study three estimation problems that are motivated by real-life applications. We propose new methods to model group testing data for both single and multiple infections. In the first problem, …

Investigating Cross Talk Between The High And Low Iron Sensors In Saccharomyces Cerevisiae, John S. Hepburn

Theses and Dissertations

Iron is essential for nearly all life on earth. Cells must maintain sufficient levels of this important nutrient due its function as a central co-factor for many cellular processes. Although iron is extremely plentiful, its poor solubility requires specialized import. On the other side, too much iron inside the cell can lead to the generation of reactive oxygen species (ROS), which have deleterious effects on many cellular functions and have been implicated in a wide variety of diseases such as cancer and Alzheimer’s disease. Using the model eukaryote Saccharomyces cerevisiae, or budding yeast, our research group has accomplished much in …

Deserts Will Bloom: Atomic Agriculture And The Promise Of Radioactive Redemption, Chris Fite

Theses and Dissertations

This paper examines the rhetorical and visual strategies used in marketing atomic agriculture to the American public from the 1940s to the 1960s. The term “atomic agriculture” refers to various agricultural research programs that used radioactive materials, particularly radioisotope tracing and mutation breeding. In print and on screen, atomic boosters from government and industry offered the promise of a better world made possible by applying atomic energy to agriculture. I argue that the proponents of atomic agriculture combined futurism and nostalgia to create a techno-pastoral vision. They hearkened back to the nineteenth century while simultaneously imagining a bright postwar future. …

Development Of Reactions And Methods For Labeling Biomolecules In Cells, Enoch Agbesi Adogla

Theses and Dissertations

The complexity of cellular environments presents a challenge to efforts at studying and elucidating biomolecules in cells. Covalent ligation of biomolecules with fluorescent molecules that have a reactive functional group that can react with a complementary functional group on biomolecules is one way that has been utilized to study biomolecules. It enables visualization and tracking of ligation and transportation of molecules within the cell. However, the myriad of functional groups within the cell makes achieving selectivity difficult. To circumvent this problem, reactions that do not interfere with biology have been developed. These reactions, referred to as bioorthogonal reactions must be …

Investigating The Function Of Aintegumenta-Like6 (Ail6) In Arabidopsis Flower Development, Han Han

Theses and Dissertations

AINTEGUMENTA (ANT) and AINTEGUMENTA-LIKE6 (AIL6) encode related transcription factors with partially overlapping roles in floral organ development in the model plant Arabidopsis thaliana. ANT and AIL6 do not make equivalent contributions to these processes. Loss of ANT function by itself results in smaller flowers, demonstrating that the role of ANT in organ size control cannot be provided by AIL6. Loss of AIL6 function on its own has no phenotypic consequences indicating that all of its roles in flower development can be provided by ANT or some other genes. To further probe the function of AIL6 in flower development, we investigated …

Relationships Of Chronotype, Social Jetlag, Sleep, Physical Activity And Diet With Mood, Perceived Stress, Obesity, Blood Pressure And Prostate Cancer, Daria M. Mcmahon

Theses and Dissertations

Background: Chronotype, social jetlag, poor sleep, proinflammatory diet, and low physical activity have been associated with increased risk of chronic diseases: obesity, diabetes, cardiovascular disease, depression and cancer. Yet the relationships between these factors have not been extensively investigated in prospective studies.

Methods: Two studies were conducted. The first study followed 390 healthy men and women ages 21-35 for two years. Social jetlag [SJL] and sleep measures (total sleep time [TST], sleep onset latency [SOL], wake after sleep onset [WASO]), sleep efficiency [SE]), were derived from physical activity personal (armband) monitoring. The participants wore the armband for 4-10 …

The Effect Of Arsenic On Type 2 Diabetes And Inflammation, Kayla Penta

Theses and Dissertations

Arsenic, a ubiquitous environmental contaminant, has been shown to cause a number of health effects. At high concentrations the inorganic form is a well-known toxin, but at lower concentrations the effects range from various cancers, to cardiovascular disease and type 2 diabetes. At higher concentrations of arsenic (500- 1000μg/L) there have been epidemiological studies conducted demonstrating an increased risk in the development of type 2 diabetes with this exposure. At lower levels of arsenic exposure (<500 μg/L) the epidemiological results are inconclusive. Arsenic is also an immunotoxicant, meaning that it will cause changes in the immune response. The changes in the immune response will vary depending on a number of variables, including amount of arsenic exposure, forms of exposure and route of exposure. We wanted to determine if arsenic could modulate the immune system, and if this change could lead to an increase in susceptibility to type 2 diabetes development. We chose to examine this in C57BL/6 and db/+ mice – two non-susceptible strains. After 8 weeks (4 weeks old to 12 weeks old) of low dose inorganic arsenic exposure (50 μg/kg or 500 μg/kg) we evaluated changes in body composition, glucose tolerance and immune response. We saw that there were differences based on sex, genotype and treatment group present after the 8-week treatment period in body composition, while there were minimal changes in glucose tolerance. Finally, the immune response showed great variability depending on sex, genotype and treatment group. This project has demonstrated that while we are trying to compare differences in in vivo and epidemiological studies to find a link between arsenic and type 2 diabetes, there may be deeper levels of complications based on individual variability to arsenic exposure.

Public Perceptions Of Genetically Modified Food On Social Media: A Content Analysis Of Youtube Comments On Videos, Nanlan Zhang

Theses and Dissertations

Controversy about genetically modified (GM) food prevails on social media. Discussion about GM food includes the implementation of mandatory labeling as well as public concerns about potential health hazards posed by GM food. Previous studies mainly focus on traditional press and broadcast media, few investigate such controversial topics on social media. Interested in public opinion about this issue and possible influences of social media on public opinion, this study uses quantitative content analysis to examine the characteristics of user comments on a specific social media platform, YouTube. The purpose of the study is to investigate YouTube comments from several aspects, …

Ashley's Sister, Christina Phillips

Theses and Dissertations

This nonfiction project is a memoir, constructed in sections, about my relationship with my sister with an intellectual disability.

Preservice Teachers' Beliefs About Play In Kindergarten, Michelle Taylor Clevenger

Theses and Dissertations

The purpose of this research was to gain insight into preservice teachers’ beliefs about play in kindergarten, and explore differences in beliefs about play between teachers just beginning their education program and those who are completing their degree. The study examined the beliefs of two groups of preservice teachers: one at the beginning of their early childhood education program (beginning students) and one at the end (teacher candidates). This study used a mixed methods approach including a survey with both Likert scale and open-ended questions as well as individual interviews. Data were collected at the beginning of the fall semester …

Ain't Misbehavin': Phenomenological Inquiry Into Black Male Experiences Of School, Kelly N. Ferguson

Dissertations

Disproportionate representation of Black male students in subjective areas of discipline has long been documented. Research indicates that racial disparities in discipline have been found with insufficient evidence to support that Black or other minority students are simply misbehaving more than others. Differences in cultural orientations between Black males and their predominantly White and female teachers have been linked to bias that disproportionality impacts discipline for these students. Through phenomenological inquiry, this study explored the schooling, professional, and mentoring experiences of successful Black men to better understand how schools and communities contribute to their resilience. This research sought to uncover …