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Anders Breivik And Elliot Rodger: Violence, Communication, And The Mediated Sphere., Walter Anthony Lucken Iv

Wayne State University Theses

The “mass shooting” has become a major hallmark of everyday news and discussions in mass media. Through the lens of two specific cases, this research situates the mass shooting within a few preexisting historical continuities and disciplines. The mass shooting is read as a communicative media event, and is considered from the perspective of mass media proliferation, political violence, discourse, semiotics, and turn of the century cultural antagonisms. The methods employed herein are textual analysis, rhetorical analysis, and post-Marxian models of historical causation.

The mass shooting is an outgrowth of global consolidation and proliferation of mass media. The mass shootings …

The Role Of Alarmins, Invariant Nkt Cells And Senescence In The Pathophysiology Of Sterile Intra-Amniotic Inflammation, Olesya Plazyo

Wayne State University Dissertations

Preterm birth is defined as the delivery of a live baby prior to the 37th week of gestation. It is the leading cause of neonatal mortality worldwide. Preterm neonates are at a higher risk for short- and long-term complications, and prematurity places significant burden on our society. Elucidation of the mechanisms that lead to spontaneous preterm labor will enable development of therapies to prevent this syndrome. We aimed to study pathological inflammation that is implicated in the pathophysiology of spontaneous preterm labor.

Pathological inflammation can be initiated by the activation of innate immunity either by microorganisms or alarmins, which are …

Characterization Of The Yeast Cysteine Desulfurase Complex Within The Mitochondrial Fe-S Cluster Biogenesis, Dulmini Pabasara Barupala

Wayne State University Dissertations

Disrupted iron homeostasis within the human body materializes as various disorders. Pathophysiology of many of them relates to iron induced oxidative damage to key cellular components caused by iron accumulation within the tissues. Pertaining to the growing occurrence, cost of patient care and devastating burden associated with these diseases, the call for understanding the role of iron homeostasis within these disorders becomes inevitable. Being an abundant iron containing cofactor, the role of Fe-S clusters in cellular iron homeostasis is indisputable in the case of Friedreich’s ataxia, a disease caused by a deficiency in the protein frataxin that is indispensable during …

Interstate Groundwater Law Revisited: Mississippi V. Tennessee, Noah D. Hall, Joseph Regalia

Law Faculty Research Publications

No abstract provided.

Mind The Gap, Charles H. Ii Brower

Law Faculty Research Publications

No abstract provided.

"Where We May Oftener Converse Together": Translation Of Written And Spoken Communication In Colonial Pennsylvania, Jenna E. Fleming

The Gettysburg Historical Journal

In this paper I examine the differences between colonists’ and Indians’ perceptions and use of language in early Pennsylvania. Through consideration of translation challenges in both spoken and written contexts, I conclude that while residents of the region created systems for coping with linguistic issues, basic disparities between native and colonial forms of communication persisted in complicating diplomatic relations. The title of the paper is taken from the August 26, 1758 entry in The Journal of Christian Frederick Post and is part of the Pennsylvanian government’s proposal for closer relations with Indians.

Effect Of Anthelminthic Treatment On Helminth Infection And Related Anaemia Among School-Age Children In Northwestern Ethiopia, Yonas Yimam, Abraham Degarege, Berhanu Erko

Journal Articles: Epidemiology

BACKGROUND: Information about improvements in the health status of population at-risk of helminth infection after anthelminthic treatment helps to evaluate the effectiveness of the large scale deworming program. The objectives of this study were to assess the impact of anthelminthic treatment on the prevalence and intensity of intestinal helminth infection, haemoglobin level and prevalence of anaemia among school-age children.

METHODS: A total of 403 children attending Tikur Wuha Elementary School in Jiga, northwestern Ethiopia were enrolled in this study between February and March 2011. Formol-ether concentration and Kato-Katz methods were used to examine stool for intestinal helminth infections at baseline …

Epidemiology Of Plasmodium And Helminth Coinfection And Possible Reasons For Heterogeneity, Abraham Degarege, Berhanu Erko

Journal Articles: Epidemiology

Understanding the impact of helminth infections on clinical malaria is useful for designing effective malaria control strategies. Plenty of epidemiological studies have been conducted to unravel the nature of interactions between Plasmodium and helminth infection. Careful broad summarization of the existing literature suggests that Schistosoma mansoni and hookworm infections may increase the risk of clinical malaria and associated morbidities, but Trichuris trichiura infection is not associated with the occurrence of clinical malaria and related outcomes. However, findings about effect of Ascaris lumbricoides and Schistosoma haematobium infection on clinical malaria are contradictory. Furthermore, the nature of relationship of helminth infection with …

Impact Of N-Acetyl-L-Cysteine On The Pathology Of Experimental Parkinson’S Disease In Vivo, Negin Nouraei

Electronic Theses and Dissertations

Parkinson’s disease is a progressive neurodegenerative disorder associated with disruptions in motor as well as non-motor functions, such as cognitive and olfactory impairments. Postmortem tissue from Parkinson’s patients shows evidence of oxidative stress in dopaminergic neurons and hallmark proteinaceous inclusions known as Lewy bodies in multiple brain regions spanning the medulla oblongata to the telencephalon. There are no therapies that decelerate the progression of this disease. Thus, the major goal of the present study was to test the therapeutic potential of two neuroprotective molecules, the antioxidant thiol N-acetyl-L-cysteine (NAC) and the steroid neuromodulator dehyroepiandrosterone sulfate (DHEAS), in experimental models of …

Vico's Narrative Art: From The Forests To The Academies, Ariana Ragusa

Electronic Theses and Dissertations

In this dissertation, I argue that Giambattista Vico (1668-1744), most famously considered a philosopher of history, is above all a philosopher of narration. I unfold Vico’s narrative response to and rejection of traditional philosophical discourse; through relating the story of himself and the story of mankind, Vico demonstrates that storytelling gives birth to the human self and world. Furthermore, I emphasize the ontological import of narrative, often overlooked, in his two major works, The Autobiography of Giambattista Vico and The New Science. Finally, I conclude by showing the relevance of Vico’s pedagogical call to cultivate the child’s narrative imagination in …

Attitudes Of Pre-Service Teachers Toward Computational Thinking In Education, Bekir Mugayitoglu

Electronic Theses and Dissertations

The purpose of the study was to examine the attitudes of pre-service teachers toward computational thinking, before and after an intervention, to convey the importance of integrating computational thinking into K-12 curricula. The two-week, course-embedded intervention introduced pre-service teachers, with varying academic specialties, to computational thinking practices and their utility. The intervention employed the Scratch programming language tool including Scratch flashcards, everyday and interdisciplinary examples of computational thinking, and unplugged activities. The findings indicated that the intervention was an effective new way to convey the value of computational thinking to all sampled pre-service teachers, no matter their academic specialties or …

A Decade (2005-2015) Of Unconventional Shale Gas Development In Washington County, Pennsylvania, And Its Environmental Impact, Colleen Nolan

Electronic Theses and Dissertations

Unconventional shale gas extraction has grown significantly over the past decade in Washington County, Pennsylvania; 1362 unconventional wells had been drilled by the end of 2015. This study analyzed ten years of industry data to generate an overview of development and assess the resultant environmental impacts. Analyses of industry data obtained from PADEP and DCNR indicate well longevity may be overestimated while land and water usage is underestimated. To evaluate possible water quality impacts, a survey was conducted, with 99 ground and surface water samples collected and analyzed. 82% of samples exceeded at least one EPA (S)MCL, with iron exceeded …

Meyer, Pierce, And The History Of The Entire Human Race: Barbarism, Social Progress, And (The Fall And Rise Of) Parental Rights, Jeffrey Shulman

UC Law Constitutional Quarterly

This article examines the significance of the United States Supreme Court decisions in Meyer v. Nebraska and Pierce v. Society of the Sisters under the backdrop of shifting views on what constitutes appropriate state regulation of education. On its face, the question of how a state may regulate education may not seem so controversial. However, the idea that the state could mandate public education and take children from their parents conflicted with traditional views of family autonomy and parental authority.

Progress would occur with the steady diminution of state authority, but under the guidance of the court. Part I of …

Fields V. Twitter, Inc. Reply To Opposition To Motion To Dismiss Second Amended Complaint

Section 230 Archives

No abstract provided.

Attic Salt, 2016, Loyola Marymount University, The Honors Program

Attic Salt

No abstract provided.

Structured Copd Discharge Education And Quality Of Life: A Feasibility Evaluation, Patricia B. Conley

MUSC Theses and Dissertations

Background: Multiple internal and external factors are responsible for the development and progression of chronic obstructive pulmonary disease (COPD). Noxious stimuli such as cigarette smoking and other air borne pollutants set off the ongoing inflammatory process of COPD resulting in air flow limitation and lung tissue destruction. Objectives: Examination of inflammatory mediators of COPD and risk factors that coincide with hospital admission for AECOPD. The aim of this dissertation was to conduct a feasibility study to implement an educational intervention for hospitalized patients and evaluate their quality of life (QOL), using the RE-AIM framework to evaluate outcomes. Design: This dissertation …

Fcrl As A Target For Immunotherapy Of B-Cell Lymphoma, Mollie Capone

MUSC Theses and Dissertations

Current treatments for B-cell lymphomas are largely non-specific and survival rates among those diagnosed with aggressive subtypes of non-Hodgkin’s lymphoma (NHL) remain poor. Thus, there is a demand for immune therapies that could reduce cyto-toxicity and improve outcomes. While B-cell lymphoma tumor cells express HLA class II molecules, there are multiple defects in functional HLA class II antigen (Ag) presentation to CD4+ T-cells. Studies in our laboratory suggest that in a subtype of non-Hodgkin’s lymphoma, Burkitt’s Lymphoma (BL) there are associated molecules that may disrupt CD4+ T cell recognition of malignant B-cells. To dissect the role of BL-associated molecules in …

Epigenetic Regulation Of Microrna Expression During Pathological Cardiac Remodeling And Fibrosis, Ludivine Renaud

MUSC Theses and Dissertations

This dissertation aims to develop a better understanding on how epigenetics regulate microRNAs during pathological cardiac remodeling and fibrosis. Histone modifications by acetylation and/or methylation, DNA methylation and miRNAs are epigenetic mechanisms that play an essential role during development and differentiation. In the light of recent studies, there is strong evidence linking epigenetics to the pathogenesis of a variety of diseases, including cancer, fibrotic diseases and heart failure. MicroRNAs have emerged as major players in the progression of heart failure yet the transcription of microRNAs in heart failure is poorly understood. An important aspect of epigenetic regulation is cross-talk between …

A Vernacular Of Surveillance: Taylor Swift And Miley Cyrus Perform White Authenticity, Rachel E. Dubrofsky

Communication Faculty Publications

This article looks at popular visual media in the context of the larger surveillance society in which it occurs. Bringing into conversation scholarship in feminist media studies, surveillance, performance, and critical race studies, the piece offers another way to explore race in popular media and consider the implications of surveillance. The work examines how principles from contexts of surveillance carry over into contexts not under surveillance. The article explores the vernacularization-the process of making things mundane, everyday, unremarkable-of ideas about authenticity and performing, and the implications when it comes to race issues, which are animated in contexts of surveillance, but …

The Self Is A Moving Target: The Neuroscience Of Siri Hustvedt's Artists, Jason Tougaw

Publications and Research

No abstract provided.

Non-Nad-Like Poly(Adp-Ribose) Polymerase-1 Inhibitors Effectively Eliminate Cancer In Vivo, Colin Thomas, Yingbiao Ji, Niraj Lodhi, Elena Kotova, Aaron Dan Pinnola, Konstantin Golovine, Peter Makhov, Kate Pechenkina, Vladimir Kolenko, Alexei V. Tulin

Publications and Research

The clinical potential of PARP-1 inhibitors has been recognized N10 years ago, prompting intensive research on their pharmacological application in several branches of medicine, particularly in oncology. However, natural or acquired resistance of tumors to known PARP-1 inhibitors poses a serious problemfor their clinical implementation. Present study aims to reignite clinical interest to PARP-1 inhibitors by introducing a new method of identifying highly potent inhibitors and presenting the largest known collection of structurally diverse inhibitors. The majority of PARP-1 inhibitors known to date have been developed as NAD competitors. NAD is utilized by many enzymes other than PARP-1, resulting in …

Exploring Literary Analysis: Techniques For Understanding Complex Literature, Lindsay Persohn

Teaching and Learning Faculty Publications

No abstract provided.

Biology Discipline 5-Year Plan 2016-2021, Biology Discipline

Assessment of Student Learning Reports

No abstract provided.

Teachers As Leaders: ​Action Research In The Classroom, Teresa Lester, Stephanie Mccabe

Instructional Modules for Professional learning Responding to Opportunities and Valuing Educators (IMPROVE)

The purpose of this module is to explore means in which teacher leaders can utilize the process of action research to improve outcomes for students. Participants who utilize this module will learn the "habits of mind" --assessing performance, analyzing problems they encounter in the classroom, prescribing an intervention, monitoring performance, learning from experience (Sagor, 2000) --to continue the work of professional educators. Additionally, the use of action research as professional development assures teacher leaders and school administrations that their teachers will use new knowledge for the pursuit of effective strategies for student learning.

Visit professional learning module.

What If I Can't Plc?, Lindsay Lee, Audrey Moore, Angela Szakasits, Cynthia Wortham

Instructional Modules for Professional learning Responding to Opportunities and Valuing Educators (IMPROVE)

The purpose of this learning module is to provide information for teachers and administrators to learn ways to overcome barriers to participate in PLCs. The goal of this learning module is to provide teachers and administrators with resources to employ facilitation skills, create trust among colleagues, develop collective wisdom, build ownership, and take action to support student learning.

Visit professional learning module.

Reproduction And Recruitment Of American Lobster (Homarus Americanus) In The Great Bay Estuary, New Hampshire, Elizabeth M. Morrissey

Master's Theses and Capstones

The overall goal of this research project was to determine if lobsters reproduce and settle in the Great Bay estuary (GBE), NH. First, I mapped the distribution and abundance of ovigerous lobsters carrying late-stage eggs in the estuary, during May and June of 2015. Ovigerous lobsters were concentrated in Little Bay and adjacent sections of the Piscataqua River, with CPUE in these areas of 0.12 ± 0.02 lobsters/trap haul. Very few were found in the regions furthest from the coast. Next, egg samples were collected from these lobsters, as well as from ovigerous lobsters captured along the NH coast and …

Oxytetracycline And Thermal Marking Of Alewife (Alosa Pseudoharengus) Otoliths, Steven M. Luell

Master's Theses and Capstones

Alewives (Alosa pseudoharengus) are anadromous clupeids native to the east coast of North America. With their population in decline, there is increasing interest in releasing hatchery-reared alewives for stock enhancement. As a result, techniques are needed to produce long-lasting marks to identify stocked fish. The objective of this investigation was to evaluate the efficacy of marking alewives using oxytetracycline immersion and thermal marking techniques. Oxytetracycline marking trials consisted of immersing alewife larvae in three concentrations of oxytetracycline (200, 400, and 600 mg/L) for two durations (4 and 6 hours). Sagittal otoliths were removed and examined for marks with an epifluorescence …

Bridges Instead Of Borders: A Look Into Hispanic-American Literature And Its Effect On Hyphenated Youth, Cristal Villarreal

Undergraduate Honors Theses

No abstract provided.

Dry And Alive: Applications Of Anhydrobiosis In The Preservation Of Eukaryotic Cells, Daniel A. Webster

Undergraduate Honors Theses

First discovered in the 1980's, late embryogenesis abundant (LEA) proteins now play an important role in the modern paradigm of anhydrobiosis. These proteins are intrinsically disordered in the hydrated state, and gain more defined secondary structure motifs (e.g. beta-sheets and alpha-helices) during the process of dehydration. This gain in secondary structure likely plays a key role in the ability of LEA proteins to protect the machinery important to life sustaining processes within the cell during severe water stress. Methods such as high resolution respirometry offer insight into the level of protection conferred by these proteins during periods of acute water …

Effects Of Turbidity On The Vision And Behavior Of Longear Sunfish, Lindsey Denea Caudle

Undergraduate Honors Theses

Fish are known to use vision in many essential behaviors, including foraging, intraspecific communication and predator avoidance. Turbidity is one of the many environmental factors potentially affecting vision quality. I examined the behavior of interacting conspecific fish in varying levels of turbidity to determine how this environmental variable affects vision and behavior. Experiments were designed to observe how longear sunfish, Lepomis megalotis, reacted to visual cues - in this case a conspecific fish in a glass jar - in the presence or absence of turbidity. My hypothesis is that sunfish will display territorial behavior when introduced to another fish …