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2016

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Prothymosin-Α Variants Elicit Anti-Hiv-1 Response Via Tlr4 Dependent And Independent Pathways, G. Luca Gusella, Avelino Teixeira, Judith Aberg, Vladimir N. Uversky, Arevik Mosoian Jan 2016

Prothymosin-Α Variants Elicit Anti-Hiv-1 Response Via Tlr4 Dependent And Independent Pathways, G. Luca Gusella, Avelino Teixeira, Judith Aberg, Vladimir N. Uversky, Arevik Mosoian

Molecular Medicine Faculty Publications

Prothymosin α (ProTα) (isoform 2: iso2) is a widely distributed, small acidic protein with intracellular and extracellular-associated functions. Recently, we identified two new ProTα variants with potent anti-HIV activity from CD8+ T cells and cervicovaginal lavage. The first is a splice variant of the ProTα gene known as isoB and the second is the product of ProTα pseudogene 7 (p7). Similarly to iso2, the anti-HIV activity of both variants is mediated by type I IFN. Here we tested whether the immunomodulatory activity of isoB and p7 are also TLR4 dependent and determined their kinetic of release in response to HIV-1 …

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Truth, Justice, And The Common Good: Core Capstone Final Essay, Valentina De Santis (Class Of 2016) Jan 2016

Truth, Justice, And The Common Good: Core Capstone Final Essay, Valentina De Santis (Class Of 2016)

Writing Across the Curriculum

The course Truth, Justice, and the Common Good brought awareness to themes of the environment, common good, and social issues. Environmental justice is the involvement of the society to respect and care for environmental laws and regulations. It is a part of the common good to appreciate and respect the natural world. The common good is customized toward every individual and it is the decision of the human being to recognize the common good daily. From the readings and presentations in class, a correlation was formed between beliefs and values towards topics in religion, justice, and community.

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Bigger By The Dozens: The Prevalence Of Afro-Based Tradition In Battle Rap, Shingi Mavima Jan 2016

Bigger By The Dozens: The Prevalence Of Afro-Based Tradition In Battle Rap, Shingi Mavima

Journal of Hip Hop Studies

This paper interrogates the linguistic grounding of battle rap in Afro-based cultural practices, and the transformative power the understated art form possesses within the African American community. An integral part of hip-hop from the beginning, 'battling' has grown into a distinct subculture in recent years. Because of its oft-unmitigated rawness, it is often viewed as a lesser artistic form that embodies the worst of the violence, misogyny and other societal ills that hip-hop is accused of promoting. This paper argues that battle rap is not a corruption of Black culture: it is the modern incarnation of long-held oral, competitive, and …

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Feasibility Of Integrating Tripterygium Wilfordii Into Modern Cancer Therapy For Increased Efficacy With Minimal Toxicity, Andy Vo Jan 2016

Feasibility Of Integrating Tripterygium Wilfordii Into Modern Cancer Therapy For Increased Efficacy With Minimal Toxicity, Andy Vo

AUCTUS: The Journal of Undergraduate Research and Creative Scholarship

Cancer is the second leading cause of death in the U.S., and millions of novel cancer cases are being diagnosed each year. While chemotherapy and ionizing radiation are effective treatments against these malignant tumors, the adverse effects that accompany such treatments are devastating. In order to find alternative treatment methods with less side effects, we turn to Eastern herbal medicine. Recent scientific research has found that Tripterygium wilfordii, an herbal medicine traditionally used to treat inflammation in China, contains compounds (triptolide and celastrol) that prevent the growth of solid tumors, induce apoptosis, and prevent metastasis of developed tumors. Investigations on …

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Free Tilly?: Legal Personhood For Animals And The Intersectionality Of The Civil & Animal Rights Movements, Becky Boyle Jan 2016

Free Tilly?: Legal Personhood For Animals And The Intersectionality Of The Civil & Animal Rights Movements, Becky Boyle

Indiana Journal of Law and Social Equality

No abstract provided.

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The Biodiversity Paradigm Shift: Adapting The Endangered Species Act To Climate Change, Kalyani Robbins Jan 2016

The Biodiversity Paradigm Shift: Adapting The Endangered Species Act To Climate Change, Kalyani Robbins

Fordham Environmental Law Review

No abstract provided.

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Lessons From The Wolf Wars: Recovery V. Delisting Under The Endangered Species Act*, Martha Williams Jan 2016

Lessons From The Wolf Wars: Recovery V. Delisting Under The Endangered Species Act*, Martha Williams

Fordham Environmental Law Review

No abstract provided.

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Episodic Memory, Hippocampal Volume, And Effects Of Premature Birth In Young Children, Dana Marie Anderson Jan 2016

Episodic Memory, Hippocampal Volume, And Effects Of Premature Birth In Young Children, Dana Marie Anderson

Wayne State University Theses

The hippocampus is essential for episodic memory. Preterm birth is associated both with deficits in episodic memory and with alteration on hippocampal structure; however, the effect of term status on the relation between episodic memory and hippocampal volume (HCV) is unclear. We studied the potential of a latent construct of episodic memory as well as the relation between episodic memory and HCV in full-term and preterm born children (ages 5-6). The individual episodic memory measures separated into different components based on the level of association and decision that was required for the tasks. The composite scores were not significantly correlated …

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Personality Trait Interactions With Narrator Empathy In A Brief Computerized Intervention, Jennifer Danielle Ellis Jan 2016

Personality Trait Interactions With Narrator Empathy In A Brief Computerized Intervention, Jennifer Danielle Ellis

Wayne State University Theses

Computer-delivered, brief interventions (CDBIs) have been an increasingly popular way to treat substance use disorders; however, very few studies have examined which characteristics of CDBIs maximize intervention effectiveness. The literature has consistently demonstrated that therapist empathy is associated with reduced substance use; however, it is unclear whether this principal applies to CDBIs. Therefore, one aim of this study was to examine whether the presence of an empathic narrator increases motivation to reduce heavy drinking in a CDBI. A second aim was to examine whether an individual’s personality traits (empathy, psychopathy, and Big Five Traits) interact with treatment characteristics (specifically high …

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Corporations And The Limits Of State-Based Models For Protecting Fundamental Rights In International Law, David Bilchitz Jan 2016

Corporations And The Limits Of State-Based Models For Protecting Fundamental Rights In International Law, David Bilchitz

Indiana Journal of Global Legal Studies

At the heart of international law lies a central tension. On the one hand, the fundamental rights recognized in international treaties protect the fundamental interests of individuals, obligating all actors who can affect these rights. One the other hand, international law has often been conceived of as a system in which the only legitimate actors are states. In turn, only states can be bound by the fundamental rights obligations in international treaties. To address this tension, two models have been proposed. The first is an "Indirect duty" approach, whereby the state remains the primary duty-bearer and must itself "create" the …

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One Pillar: Legal Authority And A Social License To Operate In A Global Context, Hans Lindahl Jan 2016

One Pillar: Legal Authority And A Social License To Operate In A Global Context, Hans Lindahl

Indiana Journal of Global Legal Studies

The claim that businesses have a social license to operate acquires concrete form in the second pillar of the U.N. Guiding Principles on Business and Human Rights (UNGPs) in the fundamental distinction between "compliance with all applicable laws" and "respect for human rights." The aim of this paper is to critically examine the presuppositions that undergird this distinction and to explain how and why moving beyond state-centered thinking about law, in response to violations of human rights by globally operating businesses, requires acknowledging that there is one pillar that embraces states and businesses: the legal obligation to comply with international …

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Transformation Of The Prescott Foursquare Church: Becoming A Church Planting Church, John W. Gooding Jan 2016

Transformation Of The Prescott Foursquare Church: Becoming A Church Planting Church, John W. Gooding

All Electronic Theses and Dissertations

This study is a qualitative study of the Prescott Foursquare Church and its transformation from a small, broken denominational church to a disciple making and church planting fellowship of churches. The project sought to discover the key trigger events or processes that brought about church growth in the Prescott church and led to the growth of a fellowship of over twenty-two hundred churches in one hundred and sixteen countries. The result of interviews of pastors and review of historical data of the church and Christian Fellowship Ministries was the discovery of a discipleship culture in the local congregation in Prescott …

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Rerum Novarum: New Things And Recent Paradigms Of Property Law, M.C. Mirow Jan 2016

Rerum Novarum: New Things And Recent Paradigms Of Property Law, M.C. Mirow

University of the Pacific Law Review

No abstract provided.

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Making Resources, Making Management, Jacquelyn Amour Jampolsky Jan 2016

Making Resources, Making Management, Jacquelyn Amour Jampolsky

University of the Pacific Law Review

No abstract provided.

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Using International Property Law As A Lever To Evolve Toward Integrative Ocean Governance, Rachael E. Salcido Jan 2016

Using International Property Law As A Lever To Evolve Toward Integrative Ocean Governance, Rachael E. Salcido

University of the Pacific Law Review

No abstract provided.

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Not Affirmative Consent, Aya Gruber Jan 2016

Not Affirmative Consent, Aya Gruber

University of the Pacific Law Review

No abstract provided.

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Barriers To Affirmative Consent Policies And The Need For Affirmative Sexuality, Kristen N. Jozkowski Jan 2016

Barriers To Affirmative Consent Policies And The Need For Affirmative Sexuality, Kristen N. Jozkowski

University of the Pacific Law Review

No abstract provided.

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The Communistic Incliantions Of Sir Thomas More, David Ray Papke Jan 2016

The Communistic Incliantions Of Sir Thomas More, David Ray Papke

University of the Pacific Law Review

No abstract provided.

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Is The High Frequency Of Postoperative Atrial Fibrillation After Cardiac And Lung Surgeries Related To Hypomagnesemia And Releases Of Ceramides And Platelet-Activating Factor?, Burton M. Altura, Nilank C. Shah, Gatha J. Shah, Aimin Zhang, Wenyan Li, Bella T. Altura Jan 2016

Is The High Frequency Of Postoperative Atrial Fibrillation After Cardiac And Lung Surgeries Related To Hypomagnesemia And Releases Of Ceramides And Platelet-Activating Factor?, Burton M. Altura, Nilank C. Shah, Gatha J. Shah, Aimin Zhang, Wenyan Li, Bella T. Altura

Touro College of Osteopathic Medicine (Middletown) Publications and Research

The authors discuss the possible role of hypomagnesemia, ceramides and platelet-activating factor in the incidence of postoperative atrial fibrillation after cardiac and lung surgeries.

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Dedication: Michael P. Mcnulty, Roger Williams University Law Review Staff Jan 2016

Dedication: Michael P. Mcnulty, Roger Williams University Law Review Staff

Roger Williams University Law Review

No abstract provided.

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Macdonald-Miller Correspondence, Norman Miller, Duncan Macdonald Md Jan 2016

Macdonald-Miller Correspondence, Norman Miller, Duncan Macdonald Md

Dartmouth Scholarship

This file is an exchange of letters, e-mails, and documents between Norman Miller and Duncan MacDonald, MD, including a four-volume collection of MacDonald’s writings, over a 30-year period, all on witchcraft, some 600 pages extracted from the original 1100. As such, the following material is unfinished, presenting sketches of ideas, concepts, and arguments.

Duncan MacDonald served as a physician in Zambia and Kenya, including a period as a "Flying Doctor". He later served as a provincial psychiatrist in Cornwall, UK. His parallel interests in economic development and international witchcraft issues led to long-term research on these issues, the witchcraft concerns …

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Epigenetic Response To Environmental Change: Dna Methylation Varies With Invasion Status, Aaron W. Schrey, Travis R. Robbins, Jacob Lee, David W. Dukes Jr., Alexandria K. Ragsdale, Christopher J. Thawley Jan 2016

Epigenetic Response To Environmental Change: Dna Methylation Varies With Invasion Status, Aaron W. Schrey, Travis R. Robbins, Jacob Lee, David W. Dukes Jr., Alexandria K. Ragsdale, Christopher J. Thawley

Biology Faculty Publications

Epigenetic mechanisms may be important for a native species’ response to rapid environmental change. Red Imported Fire Ants (Solenopsis invicta Santschi, 1916) were recently introduced to areas occupied by the Eastern Fence Lizard (Sceloporus undulatus Bosc & Daudin, 1801). Behavioral, morphological and physiological phenotypes of the Eastern Fence Lizard have changed following invasion, creating a natural biological system to investigate environmentally induced epigenetic changes.We tested for variation in DNA methylation patterns in Eastern Fence Lizard populations associated with different histories of invasion by Red Imported Fire Ants. At methylation sensitive amplified fragment length polymorphism loci, we detected a higher diversity …

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Using Animal Models To Overcome Temporal, Spatial And Combinatorial Challenges In Hiv Persistence Research, Paul W. Denton, Ole S. Søgaard, Martin Tolstrup Jan 2016

Using Animal Models To Overcome Temporal, Spatial And Combinatorial Challenges In Hiv Persistence Research, Paul W. Denton, Ole S. Søgaard, Martin Tolstrup

Biology Faculty Publications

Research challenges associated with understanding HIV persistence during antiretroviral therapy can be categorized as temporal, spatial and combinatorial. Temporal research challenges relate to the timing of events during establishment and maintenance of HIV persistence. Spatial research challenges regard the anatomical locations and cell subsets that harbor persistent HIV. Combinatorial research challenges pertain to the order of administration, timing of administration and specific combinations of compounds to be administered during HIV eradication therapy. Overcoming these challenges will improve our understanding of HIV persistence and move the field closer to achieving eradication of persistent HIV. Given that humanized mice and non-human primate …

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A Dramaturgical Analysis Of The Miracle Worker, Abby Butzer Jan 2016

A Dramaturgical Analysis Of The Miracle Worker, Abby Butzer

All Graduate Theses, Dissertations, and Other Capstone Projects

This document is a thesis submitted in partial fulfillment of the Master of Arts degree in theatre. It is a dramaturgical analysis for William Gibson's play The Miracle Worker, providing a reference for directors and actors. The thesis explores the play's medical and pedagogical history in six chapters: the physiology and psychology of language acquisition as it pertains to sight and/or hearing impaired children, a pedagogical comparison of Samuel G. Howe and Annie Sullivan, a modern diagnosis of the fever that destroyed Helen Keller's vision and hearing, the 19th century pathology and treatment options for the disease of the eye …

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Directing Time Stands Still, Michael Bradley Sheeks Jan 2016

Directing Time Stands Still, Michael Bradley Sheeks

All Graduate Theses, Dissertations, and Other Capstone Projects

This document is a thesis submitted in partial fulfillment of the Master of Fine Arts degree in theatre. It is a detailed account of author Michael Sheeks’s artistic process in directing Time Stands Still in the fall of 2015. The thesis chronicles the director’s artistic process from pre-production through performance in five chapters: a preproduction analysis, an historical and critical perspective, a process journal, a post-production analysis and a process development analysis. Exhibits and works cited are included.

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Communication And Competence For Self-Representation, E. Lea Johnston Jan 2016

Communication And Competence For Self-Representation, E. Lea Johnston

UF Law Faculty Publications

In Indiana v. Edwards, the U.S. Supreme Court held that states may impose a higher competency standard for self-representation than to stand trial in criminal cases. While the Court articulated a number of interests relevant to representational competence, it left to states the difficult task of formulating an actual competence standard. This Article offers the first examination and assessment of the constitutionality of state standards post-Edwards. It reveals that seven states have endorsed a representational competence standard with a communication component. Additionally, twenty states have embraced vague, capacious standards that could consider communication skills. States have applied these standards to …

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Mr. Peabody's Improbable Legal Intellectual History, Mark Fenster Jan 2016

Mr. Peabody's Improbable Legal Intellectual History, Mark Fenster

UF Law Faculty Publications

Legal intellectual history, I suggest in this Paper, is the street sweeper in the parade of law’s history and its use of history. Lawyers and legal academics want great, important figures, cases, and theories with and against which they can do battle. The student-edited law reviews prefer bold, clear claims that explain why one answer to an historical question presented will bring justice, while a competing answer is manifestly unjust; why one past approach lacks principle or created worse consequences; or how one theory or another can explain all manner of thorny legal issues which bedevils academics and practitioners. Viewing …

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The Motivation Of Seniors: Why They Participate In The Senior Games, Shuhui Zheng Jan 2016

The Motivation Of Seniors: Why They Participate In The Senior Games, Shuhui Zheng

Master of Education in Applied Human Development Graduate Projects

This project mainly talks about the reasons of senior athletes why they participate in the Senior Games. It was well known that physical exercise can promote healthy lifestyles and physical condition of human beings, and large numbers of research had been done to investigate the motives and benefits of youth and adults to do exercise. However, few researchers spent their time studying the motivational orientations of elderly adults to participate in activities, exercise or sports. Hence, the first purpose of this study is to reveal the reasons of seniors why they participate in sports, and the Senior Games is a …

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Leech Host Specificity And Its Effect On Rates Of Parasitism In Two Pond Turtle Species, Sternotherus Odoratus And Chrysemys Picta, Linda Valentina Araya Jan 2016

Leech Host Specificity And Its Effect On Rates Of Parasitism In Two Pond Turtle Species, Sternotherus Odoratus And Chrysemys Picta, Linda Valentina Araya

Theses, Dissertations and Culminating Projects

Appropriate host selection by parasites is critical for ensuring offspring survival, optimal feeding location, and protection from predators. Leeches (Placobdella spp.) are known to parasitize bottom-dwelling turtle species more frequently than basking turtle species, but it is not known whether this bias is evolutionarily advantageous. I tested two potential factors that could influence host selection by leeches: differential chance of encounter due to habitat usage, and chemosensory bias of leeches toward bottom-dwelling species. I first confirmed that Chrysemys picta (Eastern painted turtle, a basking species) and Sternotherus odoratus (common musk turtle, a bottom-dwelling species) in Lake Wapalanne in Sussex County, …

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My Slovak Family: Madash Stories, From Old Country To New, Carol Steinhauer Jan 2016

My Slovak Family: Madash Stories, From Old Country To New, Carol Steinhauer

Works by Local Authors

Carol Steinhauer, a long-time resident of Bothell, Washington, is a devoted student of family history. This book gives the Madash family history as they immigrated from Slovakia to Roslyn Washington. Previously she has written Frontiersmen, Settlers, and Rustlers: the Pease Story (2014) about her maternal grandfather’s family. It is archived in the Ellensburg Library and the University of Washington Library (Pacific Northwest Special Collection). She lives with Loren Steinhauer, her husband of forty-eight years. They have two sons, two daughters-in-law, and three grandchildren. Besides family history, her interests are gardening and reading.

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