Digital Commons Network^™

Modern Vet Management Business Plan, Alaina Stanton

Honors Capstones

No abstract provided.

Indifference To Chaotic Motion May Be Related To Social Disinterest In Children With Autism, Joshua L. Haworth, Anastasia Kyvelidou, Wayne Fisher, Nicholas Stergiou

Journal Articles

Children with autism spectrum disorder tend to have little interest in the presence, actions, and motives of other persons. In addition, these children tend to present with a limited and overly redundant movement repertoire, often expressing hyperfixation and aversion to novelty. We explore whether this is related to a more fundamental lack of appreciation for various temporal dynamics, including periodic, chaotic, and aperiodic motion structures. Seven children with ASD (age, gender, and height matched with children without ASD) were asked to stand and watch the motion of a visual stimulus displayed on a large (55") video monitor. Gaze and posture …

Dashboard Compliance: Benefit, Threat, Or Both?, James Fanto

Brooklyn Journal of Corporate, Financial & Commercial Law

This Article poses the basic question that is reflected in its title and that was the subject of the conference where the Article was initially presented: whether technology poses any threats to the mission of compliance and the position of compliance officers, whether it is just another useful tool for them, or whether it is something of both. It begins by explaining the origin of compliance in broker-dealers and investment advisers and its important current position in those firms. It then discusses why compliance officers have always been drawn to technology, particularly to keep up with the business sides of …

The Role Of Streptococcus Gallolyticus Subspecies Gallolyticus In Colon Cancer Development, Jennifer L. Herold

Dissertations and Theses (Open Access)

Colorectal cancer (CRC) is the third most common cancer in men and women and is also the third most common cause of cancer death. A large body of evidence points towards the possibility that bacteria can have a significant impact on the development of cancer. It has been suggested that Streptococcus gallolyticus subsp. gallolyticus, a group D streptococci, may play a role in the development of CRC. Sg, formerly S. bovis biotype I, has been shown to be highly associated with CRC. In observing patients with either Sg bacteremia or endocarditis it was found that 25-80% of …

Maguk Scaffolds Organize A Key Synaptic Complex In Horizontal Cell Processes Contacting Photoreceptors, Alejandro Vila, Ph.D.

Dissertations and Theses (Open Access)

Synaptic processes and plasticity of synapses are mediated by large suites of proteins. In most cases, many of these proteins are tethered together by synaptic scaffold proteins. Scaffold proteins have a large number and typically a variety of protein interaction domains that allow many different proteins to be assembled into functional complexes. As each scaffold protein has a different set of protein interaction domains and a unique set of interacting partners, the presence of synaptic scaffolds can provide insight into the molecular mechanisms that regulate synaptic processes. In studies of rabbit retina, we found SAP102 and Chapsyn110 selectively localized in …

Characterization Of Vesicular Monoamine Transporter 2 And Its Role In Parkinson's Disease Pathogenesis Using Drosophila, Antonio Joel Tito Jr., Sheng Zhang

Dissertations and Theses (Open Access)

Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain. PD is also the most common neurodegenerative disorder and the second most common movement disorder. PD patients exhibit the cardinal symptoms, including tremor of the extremities, rigidity, slowness of movement, and postural instability, after 70-80% of DA neurons degenerate. It is, therefore, imperative to elucidate the underlying mechanisms involved in the selective degeneration of DA neurons. Although increasing numbers of PD genes have been identified, why these largely widely expressed genes induce …

Targeting Pd-1/Pdl-1 Signaling In The Treatment Of Osteosarcoma Lung Metastasis, Pooja Dhupkar 3012359

Dissertations and Theses (Open Access)

Osteosarcoma (OS) manifests itself as pulmonary metastasis, which is a major cause of death in OS patients. Novel treatments like immunotherapy hold promise for the treatment of OS pulmonary metastasis. However, immunosuppressive mechanisms such as binding of immune inhibitory receptor, PD-1 with PDL-1, which is upregulated in cancer cells, may cause disease relapse.

The effect of PD-1 blockade on NK cells and macrophages has not been investigated till date. The aim of this study was to determine if PD-1 blockade leads to of OS lung metastasis regression and study the role of NK cells and/or macrophages in the anti-PD-1 responses. …

Organ Specific Vascular Response To Fibrosis Affects Breast Cancer Metastatic Organotropism, Eliot S. Fletcher, Eliot S. Fletcher

Dissertations and Theses (Open Access)

The solid tumor microenvironment, pre-metastatic niche, and fibrotic environment are known to have significant biochemical and biomechanical similarities to the fibrotic environment. All have significantly increased levels of factors such as TGFβ, HIF1α, TNFα, PDGF, VEGF, FGF, interleukins and other growth factors that are known to be pro-tumorigenic. Clinical and basic science research has shown that fibrosis presents an environment that favors tumor growth, such as hepatocellular carcinoma being commonly preceded by liver cirrhosis, or bleomycin induced lung fibrosis enhancing pulmonary metastasis in mouse models of breast cancer. In addition to the evidence indicating that fibrosis enhances primary tumor growth …

Cellular And Genetic Bases Of Cold Nociception And Nociceptive Sensitization In Drosophila Larvae, Heather N. Turner

Dissertations and Theses (Open Access)

Organisms from flies to mammals utilize thermoreceptors to detect and respond to noxious thermal stimuli. Although much is understood about noxious heat avoidance, our understanding of the basic biology of noxious cold perception is gravely minimal. Numerous clinical conditions disrupt the sensory machinery, such as in patients suffering from tissue damage (from wound or sunburn), or injury to the peripheral nerves, as in patients with diabetes or undergoing chemotherapy. Our goal is to determine the genetic basis for noxious cold perception and injury-induced nociceptive sensitization using the genetically tractable Drosophila model. Using a novel "cold probe" tool and assay we …

Novel Simulation To Avoid Bias In Measurement Of Hyperpolarized Pyruvate: Demonstrated In Phantom And In Vivo, Christopher M. Walker

Dissertations and Theses (Open Access)

Dynamic nuclear polarization creates a transient hyperpolarized nuclear state that can dramatically increase the signal detected by magnetic resonance imaging. This signal increase allows real-time spectroscopic imaging of specific metabolites in vivo by magnetic resonance. Real-time imaging of both the spatial and chemical fate of hyperpolarized metabolites is showing great promise to meaningfully benefit clinical care of cancer patients. Imaging of hyperpolarized agents will have a larger clinical impact if it can function as a quantitative modality upon which clinical decisions can be made. However, quantitative measurement of hyperpolarized agents is currently difficult due to the restrictions imposed by the …

The Ontology Of Immanence: Arriving At Being In Nan Shepherd's The Living Mountain, Rachel R. Gilman

Theses and Dissertations

In response to the economic and political upheaval of World War I, Scottish Modernism explored the cultural and linguistic changes of a nation trying to identify itself amidst a world-wide conflict. Scholars and critics have considered Nan Shepherd's fiction in this context—focusing on issues of gender, female identity, language, and land—but have yet to look seriously at her work The Living Mountain and its contributions to the Modernist movement. More recently, critics like Louisa Gairn and Robert MacFarlane have called attention to Shepherd's small but powerful text in an ecocritical and philosophical light, reframing her contribution to issues of Scottish …

Development Of Stable Extractive Scintillating Materials For Quantification Of Radiostrontium In Aqueous Solutions, Ayman F. Seliman

All Theses

Strontium-90 is a fission product, and it is produced with a yield of about 6%. Strontium-90 is a major radionuclide in spent nuclear fuel, high-level radioactive wastes resulting from the processing of spent nuclear fuel, and radioactive wastes associated with the operation of reactors and fuel reprocessing plants. In addition to the four stable isotopes naturally present in soil, 90Sr is present in surface soil around the world as a result of fallout from past atmospheric nuclear weapons tests. Strontium-90 is relatively mobile and can move down with percolating water to underlying layers of soil and into groundwater. The maximum …

Suture Training Device With Computer Vision Based Information Acquisition, Anand Jagannathan

All Theses

Growth in surgical technology has given rise to numerous innovative methods to perform surgery and every surgery involves certain skills that have different learning curve. Due to significant growth in medical problems that involves surgery, there is a greater demand for good surgeons. Therefore there is a need to train aspiring surgeons into becoming an expert. Surgical training has undergone a drastic change in recent years with the advent of simulation based training, which allows novice surgeons to train and acquire essential surgical skills before performing an actual surgery. With the goal of objectively evaluating the level of expertise of …

Investigation Of Lipid Profile Patterns Along Latitude In An Eastern Australian Cline And After Stress Selection In The Laboratory, And Experiments On Stress Tolerance With Rnai Knockdown Of Lipid Biosynthesis Genes, Li Ko

School of Biological Sciences: Dissertations, Theses, and Student Research

Homeoviscous adaptation in membranes and changes in energy storage lipids such as triacylglycerols (TAGs) are the two main themes of adaptation to environmental conditions. Basal patterns of lipid compositional profile of Drosophila melanogaster along a latitudinal gradient in the eastern coast of Australia indicate variations of lipidome associated with climatic patterns. Lipidome data were collected for eight locations along the eastern Australian cline for both sexes in D. melanogaster and D. simulans. To further investigate the relationship between lipidome patterns and environmental factors, we utilized laboratory selection studies using stress conditions including high temperature tolerance, desiccation survival, and chill-coma …

Giving Credit Where Credit Is Due: Reducing Inequality With A Progressive State Tax Credit, Eric Kades

Faculty Publications

No abstract provided.

Review Of Estimation Of Parameters For Animal Populations: A Primer For The Rest Of Us By Larkin A. Powell And George A. Gale, Max Post Van Der Burg

The Prairie Naturalist

“Me? A modeler? Never!” This is the opening challenge of the book, Estimation of Parameters for Animal Populations: A Primer for the Rest of Us, by Larkin Powell and George Gale. I say “challenge” because I think this book attempts to challenge the misconception that quantitative methods are out of reach for most biologists and wildlife scientists. When many of us attend college or graduate school to study wildlife science there’s a sense that, at some point, there will be math. But it appears that the attitude of many students toward this reality is to simply suffer through the …

The Classic, Winter 2016-2017, Public Relations

The Classic, 2010-2019

Zwemer View: Diversifying: The Work of Reconciliation; Around the Green: Excellence Affirmed; Interpretacion; Raider Days; Art in the Big Apple; New M.Ed. Director; Campus Life: A Special Student; Award-Winners; Parenthood; On the Rise; Booking It; Bridge Scholars Advance Diversity Values; SID MVP; Military-Friendly; Partners in Law; Face Value: Jennifer Rogers; Great Examples: Junko (Hirasawa '70) Nagao, Glenn Van Ekeren '74, Sheila (Born '94) De Jong; Investing in the Mission: 2015-16 giving tops $5.7 million; A Place for Discovery; Red Zone: Interception; 1000 Words: A Day in the Life; No Limits: Alumni help impoverished Romanian youth reach higher; A Real Classic; …

Selection Of Efficient Taq Dna Polymerase To Optimize T-Dna Genotyping Method For Rapid Detection Of Mutant Arabidopsis Thaliana Plants, Inna B. Chastukhina, Liliia R. Nigmatullina, Lia R. Valeeva, Eugene V. Shakirov

Biological Sciences Faculty Research

Plants harbor homologues of various animal genes involved in phosphorus metabolism, telomere biology and other cellular processes. Compared to experiments with many other multicellular organisms, research in the model plant Arabidopsis thaliana takes advantage of short generation time and an ever increasing arsenal of genetic and transgenic tools, including large collections of T-DNA knockout and activation lines. The availability of thousands of publicly available transgenic Arabidopsis lines provides a unique opportunity to address a number of important biological questions. However, identification of individual T-DNA mutant plants from a pool of seeds provided by a biological stock distribution center remains a …

Forest Ecosystems Of Temperate Climatic Regions: From Ancient Use To Climate Change, Frank S. Gilliam

Biological Sciences Faculty Research

Humans have long utilized resources from all forest biomes, but the most indelible anthropogenic signature has been the expanse of human populations in temperate forests. The purpose of this review is to bring into focus the diverse forests of the temperate region of the biosphere, including those of hardwood, conifer and mixed dominance, with a particular emphasis on crucial challenges for the future of these forested areas. Implicit in the term ‘temperate’ is that the predominant climate of these forest regions has distinct cyclic, seasonal changes involving periods of growth and dormancy. The specific temporal patterns of seasonal change, however, …

Human And Asinine Postures In Apuleius’ Golden Ass, Timothy M. O'Sullivan

Classical Studies Faculty Research

This article examines the ways in which Apuleius’ Metamorphoses thematizes the contrast between the prone posture of the ass and the upright posture of the human. A long philosophical tradition, starting with Plato and Xenophon, argued that the human body was especially constructed for celestial contemplation, while the quadruped body was more suited for baser activities such as eating and sex. Physical posture thus becomes another way for Apuleius to emphasize the “unphilosophical” nature of Lucius-as-ass. Moreover, in Book 11, numerous references to celestial contemplation give the theme an ironic climax. Apuleius uses these celestial allusions, I argue, as further …

Lipan Apache Tribe Of Texas: Ethnic And Racial Identity, Ashley S. Leal

Theses and Dissertations

The findings presented in this study are based on a series of semi-structured interviews, focused on racial, ethnic and cultural identity, with 20 registered members of the Lipan Apache Tribe of Texas. Analysis of the interviews show that while members are spread across the country the basic cultural identity still remains the same: they are all cultural and tribal ambassadors to future generations and the world around them. Results indicate that interviewed members share the same aspirations of becoming federally recognized by the United States government, not for any type of benefits but to be seen as real Indians through …

Calculating Evapotranspiration Of Arundo Donax Along The Rio Grande, Jose R. Escamilla Jr.

Theses and Dissertations

Invasive species have been recorded to cause large economic and ecological impacts on various ecosystems and their services. Locally, giant reed (Arundo donax L.), a woody grass native to the Mediterranean, adversely impacts riparian ecosystems in southwestern United States by aggressively displacing their native flora and fauna. Giant reed also has become a cause of concern for national water security, especially in water-limited areas of the arid southwestern United States. The main objective of this study is to provide the first, landscape-level estimates of water use by giant reed in the United States. Evapotranspiration was monitored using the eddy …

Where And How Wolves (Canis Lupus) Kill Beavers (Castor Canadensis), Thomas Gable, Steve K. Windels, John G. Bruggink, Austin T. Homkes

Journal Articles

Beavers (Castor canadensis) can be a significant prey item for wolves (Canis lupus) in boreal ecosystems due to their abundance and vulnerability on land. How wolves hunt beavers in these systems is largely unknown, however, because observing predation is challenging. We inferred how wolves hunt beavers by identifying kill sites using clusters of locations from GPS-collared wolves in Voyageurs National Park, Minnesota. We identified 22 sites where wolves from 4 different packs killed beavers. We classified these kill sites into 8 categories based on the beaver-habitat type near which each kill occurred. Seasonal variation existed in …

Phataria Unifascialis Use Eyesight To Find Their Preferred Rock Location, December 2016, Erica Weed

Monteverde Institute: Tropical Ecology and Conservation

Sea stars living on the ocean substrate rely on multiple senses to detect touch, temperature, and chemicals in the water. They have rudimentary compound eyes similar to arthropod compound eyes on the tip of each arm. These eyes allow them to detect light and dark images and see in a wide range of directions. However, it is unclear whether sea stars use eyes in their environments, or if the ability to see influences sea star behavior. One species, Linckia laevigata, has been shown to rely on its eyesight to navigate back to its preferred reef location after being displaced. This …

Comparing Tardigrade Abundance And Diversity On Rock, Log, Live Tree, And Canopy In Monteverde, Costa Rica, December 2016, Lily Stander

Monteverde Institute: Tropical Ecology and Conservation

This study surveyed the abundance and diversity of Phylum Tardigrada across four different substrates: rock, log, live tree, and canopy, in Monteverde, Costa Rica. Tardigrades are understudied micro-invertebrates that inhabit every biome on the planet. I collected twenty-eight samples, or 140 subsamples, by hand, soaked them in water for a minimum of four hours, and surveyed for tardigrades. I found and documented forty-five tardigrades. Ninety-one percent of tardigrades found were Class Eutardigrada, while the remaining nine percent were Class Heterotardigrada. Five genera were identified: Echiniscus, Pseudechiniscus, Macrobiotus, Paramacrobiotus, and Minibiotus. The canopy and live tree substrates produced equal abundance and …

The Effect Of Prey Danger Level On The Feeding Behavior Of Orchard Spiders, Leucauge Sp., December 2016, Chirag Govardhan

Monteverde Institute: Tropical Ecology and Conservation

Predatory animals often need to consider the costs and benefits of an attack, so as to avoid getting bitten or stung. Orchard spiders, Leucauge sp., manipulate their orb-webs to detect prey that lands on their web and attack them accordingly. Generally, they bite prey to inject venom and may also wrap them in silk. This study investigated the behavioral sequences of orchard spiders when they were presented with highly dangerous prey (Atta sp. minima ants) versus low danger prey (Drosophila sp. fruit flies). I tested 60 spiders, which I classified by body size (to account for size of the spider) …

Edge Effect On Moth Richness, Abundance, And Potential Pollination Activity In A Costa Rican Cloud Forest, December 2016, Christopher Cosma

Monteverde Institute: Tropical Ecology and Conservation

Habitat loss and fragmentation are major threats to biodiversity, especially in tropical forests which house most of the world’s species. Edge effects are important considerations when investigating the impact of forest fragmentation on biodiversity, as they can lead to large, and often detrimental shifts in population, community, and ecosystem stability. The taxa-specific effects of forest edges are complex, highly variable, and poorly understood. In this study, I investigated the edge effect on moth richness, abundance, and potential pollination activity in a fragmented tropical cloud forest in Monteverde, Costa Rica by sampling moths with light traps at two different locations: in …

Anti-Predator Behavior Of Octopus Vulgaris, December 2016, Emily Miao

Monteverde Institute: Tropical Ecology and Conservation

Cephalopoda is a varied and unusual class that has occupied oceanic habitats all over the world for millions of years. One species in particular, Octopus vulgaris, or the common octopus has a nearly global range. Because of their soft bodies and lack of hard, protective outer covering octopuses are highly vulnerable to numerous predators. However, octopuses have evolved to compensate for this loss with a number of other anti-predator defenses, namely camouflage and substrate-hiding. Camouflage allows the octopuses to alter their appearance into a variety of colors, textures and shapes as they move through their environments, hiding in plain sight …

Songs From The Willow Tree: Staging Collective Inspiration For Creative Songwriting, Aubrey W. Carpenter

Undergraduate Honors Theses

The songwriting process, inspiration to song, can take many forms. This project explores a highly structured approach, using themes derived from reported individual experience to direct the creation of musical ends addressing common experience.

Design, Construction, And Preliminary Testing Of A Square Cross-Sectional Mixing Chamber, Holly Holmes-Smith

Chemical Engineering Undergraduate Honors Theses

Throughout the US, large quantities of chlorine are produced and transported by rail. In the past, train accidents led to deadly accidental releases and the need for mass evacuation. However, moving people unnecessarily may cause pandemonium or danger to health for sensitive members of the public. In these past cases, the models used for evacuation distances did not accurately predict the impact of the chlorine release, but these models did not take into account the reactivity of chlorine. Because chlorine is a highly reactive gas, it is absorbed into the surrounding environment which reduced the amount of chlorine in the …