Digital Commons Network^™

Development Of A Fundamental Autonomous Ground Vehicle Cruise Control Using Matlab And Simulink, Luis F. Martinez

Theses and Dissertations

This study presents and describes the development of a fully autonomous vehicle cruise control system covering the vehicle dynamics and control design needed to simulate such system. It encompasses obstacle avoidance, intelligent-and-optimal lane change as well as adaptive behavior. This study offers a comprehensive two-dimensional cruise control with three degrees of freedom and it is designed using active obstacle avoidance controllers. It also includes optimized fuzzy logic for optimal vehicle trajectory and an extensive array of control law methodology. The end work shows a complete simulation run using MATLAB and Simulink.

Virginia Woolf’S Fictional Biographies, Orlando And Flush, As Prefigures Of Postmodernism, Jacob C. Castle

Electronic Theses and Dissertations

This thesis examines the way in which the fictional biographies of Virginia Woolf, Orlando and Flush, prefigure central tenets of postmodern fiction. To demonstrate the postmodern elements present in Orlando and Flush, this thesis focuses on how the fictional biographies exhibit three postmodern characteristics: concern for historiography, extensive use of parody, and the denaturalization of cultural assumptions. Born from Woolf’s desire to revolutionize biography by incorporating elements of fiction alongside historical fact, these two novels parallel later works of historiographic metafiction in several key respects. Woolf’s extensive use of parody in Orlando and Flush prefigures how postmodern parody …

Pharmacokinetics, Tissue Distribution, Synergistic Activity, And Antitumor Activity Of Two Isomeric Flavones, Crystal L. Whitted

Electronic Theses and Dissertations

Flavonoids are polyphenolic secondary metabolites found in plants that have bioactive properties including antiviral, antioxidant, and anticancer. Two isomeric flavone were extracted from Gnaphalium elegans and Achyrocline bogotensis, plants used by the people from the Andean region of South America as remedies for cancer. 5,7-dihydroxy-3,6,8-trimethoxy-2-phenyl-4H-chromen-4-one (5, 7–dihydroxy- 3, 6, 8 trimethoxy flavone/ flavone A) and 3,5-dihydroxy-6,7,8-trimethoxy-2-phenyl-4H-chromen-4-one (3, 5–dihydroxy-6, 7, 8–trimethoxy flavone/ flavone B) have shown antineoplastic activity against colon cancer cell lines dependent upon their differentiation status. Pharmacokinetic studies reported herein were used to determine dosing for antitumor assays, as well as determine target tissue concentration. These included the …

A Multicenter, Observational, Homoeopathic Clinical Verification Study Of Cynodon Dactylon Revealing Symptom Prevalence In A Cohort Of 340 Patients, Rajkumar Manchanda, Parthasarathi Chakraborty, Pramodji Singh, P Pradhan, V Prasad, Ojit Singh, M Rai, Munmun Koley

Indian Journal of Research in Homoeopathy

Context: Clinical verification is an ongoing research program of the Council that verified many rare homoeopathic drugs. Aim: This study was carried out to clinically verify the "symptomatology" of Cynodon dactylon and to ascertain the prevalence of symptoms in the "improved" and "not improved" groups. Materials and Methods: The study was a multicenter, open, observational study. A total of 462 patients were enrolled after matching with the available symptom, compendium of the drug, and eligibility criteria in seven units/institutes of the Council. The medicine was prescribed in 6C, 30C, 200C and 1M potencies as per the need of each patient, …

Symptom Prevalence In A Cohort Of 147 Patients Improved With The Homoeopathic Medicine Ocimum Canum: A Multicenter, Open, Observational, Clinical Verification Study, Rajkumar Manchanda, Parthasarathi Chakraborty, K Das, M Rai, Ojit Singh, P Pradhan, Darshan Singh, Munmun Koley

Indian Journal of Research in Homoeopathy

Context: Clinical verification is an ongoing research program of the Council that verified many rare homoeopathic drugs. Aims: To clinically verify the "symptomatology" of Ocimum canum by ascertaining the prevalence of symptoms. Materials and Methods: The study was a multicenter, open, observational trial. A total of 214 patients were enrolled after matching with the available symptom compendium and eligibility criteria in seven units/institutes of the Council. The medicine was prescribed in 6C, 30C, 200C and 1M potencies as per the need of each patient, following homoeopathic principles and protocol developed by the Council. The collected data were presented in terms …

Climate Disobedience, Maxine Burkett

Duke Environmental Law & Policy Forum

In sharp contrast to the flurry of legal and policy-oriented efforts of years past, climate activists today employ protest and nonviolent civil disobedience to advance their agenda for rapid and ambitious mitigation and adaptation. In so doing, activists make explicit references to the storied past of defining social movements in American history—notably the anti-slavery movements of the 19th century and the civil rights movement of the 20th—and draw direct comparison to the moral failure igniting the relevant social movements. This article examines a topic largely ignored by the legal academy, the emerging climate movement, to assess the usefulness of its …

Genetically Engineered Crops: How The Courts Dismantled The Doctrine Of Substantial Equivalence, Trevor Findley

Duke Environmental Law & Policy Forum

No abstract provided.

The Trans-Pacific Partnership And The Construction Of A Syncretic Animal Welfare Norm, Andrew Jensen Kerr

Duke Environmental Law & Policy Forum

No abstract provided.

A River Basin Runs Through It: Evolving Understandings Of Equitable Apportionment And Water Rights At The Florida-Georgia Line, Michael Munoz

Duke Environmental Law & Policy Forum

No abstract provided.

Transgender Bathroom Rights, Catherine Jean Archibald

Duke Journal of Gender Law & Policy

After winning the right to same-sex marriage in all 50 states in June, 2015, the LGBT community is once again battling in court for its rights, this time for the right of transgender people to use bathrooms and locker rooms that match their gender identity. In its “Dear Colleague Letter on Transgender Students,” the Federal Government has recently interpreted federal law as requiring that transgender students be permitted to use bathroom and locker rooms that correspond with their gender identity in schools receiving federal funding. In two separate lawsuits, 20 states have challenged the legitimacy of this interpretation.

This Article …

The Parched Earth Of Cooperation: How To Solve The Tragedy Of The Commons In International Environmental Governance, Bryan H. Druzin

Duke Journal of Comparative & International Law

This article proposes a way to strengthen international environmental agreements, such as the Paris Agreement and the Kyoto Protocol. Multilateral environmental agreements such as these are extremely fragile. At the heart of the problem is what is known as the tragedy of the commons—a unique dynamic that viciously sabotages cooperation. The cause of this tragedy is that no one can trust that other actors will conserve the common resource, which triggers a race to the bottom—a race to deplete. Global warming and our inability to halt it is perhaps the ultimate example of a tragedy of the commons on a …

Psychophysiological Analysis Of A Pedagogical Agent And Robotic Peer For Individuals With Autism Spectrum Disorders., Mohammad Nasser Saadatzi

Electronic Theses and Dissertations

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by ongoing problems in social interaction and communication, and engagement in repetitive behaviors. According to Centers for Disease Control and Prevention, an estimated 1 in 68 children in the United States has ASD. Mounting evidence shows that many of these individuals display an interest in social interaction with computers and robots and, in general, feel comfortable spending time in such environments. It is known that the subtlety and unpredictability of people’s social behavior are intimidating and confusing for many individuals with ASD. Computerized learning environments and robots, however, prepare a predictable, …

Examining Teachers' And College Students' Perspectives Toward E-Textbooks As An Educational Tool, Nariman Ali Alawami

Dissertations

The purpose of this research was to understand the perspectives of teachers and students regarding their use of specific e-textbooks in a higher education learning environment. The e-textbooks used by the teachers and students were examined in order to determine functions and features to focus on during the inquiry. This study was particularly interested in the design of e-textbooks and how they are used by both teachers and students in the learning process. The participants in the research were also prompted to suggest improvements to e-textbooks. A case study approach was used as the methodology to examine three teachers represented …

Biology Laboratories At A Distance: A Case Study And Experiment Of Ecology And Evolution Labs With Community College Students, Beverly E. Ranney

Dissertations

Community colleges deliver more courses online; laboratory-based courses face challenges in how to do this. This study examined how ecology and evolution laboratories could effectively be delivered in an online biology community college course. Virtual simulations and hands-on, at-home kits were used in two groups. Results showed that students using the virtual simulations had higher learning gains and more positive perceptions towards their laboratory experiences than those students using athome kits. By evaluating learning gains on a pretest/posttest and utilizing interviews and focus groups, this research concluded that virtual simulations offered a superior learning experience for online learners. The results …

Using Mouse Models To Define How The P53 R72p Polymorphism Impacts The Adverse Effects Of Doxorubicin And Ionizing Radiation, Emily Dominguez

Dissertations and Theses (Open Access)

The single nucleotide polymorphism (SNP) at codon 72 of the tumor suppressor gene p53 codes for either an arginine (R) or proline (P) (p53 R72P). This SNP may impact how cells respond to genotoxic insult. Studies in cell culture and in tissues from mouse models of the SNP indicate that, in response to gentoxic treatment, the two variants may differentially induce apoptosis and expression of p53 target genes. In epidemiological studies, the P variant is associated with decreased cancer survival and increased risk of side-effects from genotoxic cancer treatment. Genotoxic therapy is still the mainstay of cancer treatment, and doxorubicin …

The Importance Of Serotonergic And Adrenergic Receptors For The Induction And Expression Of One-Trial Cocaine-Induced Behavioral Sensitization, Krista N. Rudberg

Electronic Theses, Projects, and Dissertations

Addiction is a complex process in which behavioral sensitization may be an important component. While the behavioral effects of sensitization are well established, the intricate neurobiology of the phenomenon is still largely unknown. Dopamine systems mediate the induction of behavioral sensitization in adult rats, but there is a large amount of evidence showing that other neurotransmitter systems also modulate the induction process. For example, the α1b-adrenergic and 5-HT_2A receptor systems are known to modulate the sensitized responding of adult rats, but the roles that these receptor systems play in the induction and expression of behavioral sensitization during the preweanling …

If This Heart Had A Mouth: A Forbidden Romance Narrated Through Mimesis: Poems, Julieta V. Corpus

Theses and Dissertations

If This Heart Had a Mouth consists of forty-two poems where love is the catalyst for a multitude of emotions, ranging from falling in love, to hopelessness, to a begrudging kind of acceptance at losing the beloved to somebody else. To create all forty-two poems, 23 written in Spanish, and 19 poems written in English, I employed the literary device called Mimesis which entails deriving an original poem from someone else's work.

To create each poem, I followed another poet’s original work, line by line. I imitated that poet’s rhythm through their use of meter. I counted the number of …

The Artists Journey- Strolling The Edges Of The Universe, Mary P. Williams

Theses and Dissertations

Space exploration has always fascinated me, and so has the idea ( so far fictional) that humankind may someday encounter extraterrestrial life. My series of paintings and prints are a visual expression of the awe and wonder I feel as I follow our species’s unending drive to expand the boundaries of its known world.

But the unknown is not just out there in interstellar space. And there are other lifeforms to encounter right here on our own planet. Another series of my paintings documents Earth’s flora. Our ties to the microorganisms, animals, and plants on our planet, and the life …

Heritage Tourism In Washington County, Tennessee: Linking Place, Placelessness, And Preservation, Chad F. Bailey

Electronic Theses and Dissertations

This thesis examines the formation of spatial theory and the linkage between space and place and their relationship with historic preservation and heritage tourism. First, this thesis analyzes the terms space and place, and how scholars define each term. Second, this thesis focuses on the concept of placelessness. Third, this thesis examines historic preservation as a strategy to help alleviate placelessness and as a crucial link to heritage tourism. This thesis also will use regional examples of preservation and tourism as exemplified by the preservation efforts of private organizations, citizens, and government officials in Jonesborough,Johnson City, and Washington County,Tennessee. This …

The Perceptions Of Northeast Tennessee Educators Regarding Arts Integration, Philip A. Wright

Electronic Theses and Dissertations

The purpose of this quantitative study was to determine the perceptions of Northeast Tennessee Educators regarding arts integration. Specifically this study was an examination of the perceptions of district and K-8 school level administrators, K-8 general classroom teachers of math, science, social studies, or literacy, and K-8 arts specialists of dance, drama, music, or visual arts. Nine school districts in Northeast Tennessee agreed to participate in the study. Data were collected through an online survey system, SurveyMonkey.com. Data from 179 participants were used in the study. Seventeen items from the survey were measured on a 5-point Likert scale. Those items …

Structural And Functional Analysis Of Grapefruit Flavonol-Specific-3-O-Gt Mutant P145t, Sangam Kandel Mr

Electronic Theses and Dissertations

This research is focused on the study of the effect of mutating proline 145 to threonine on the substrate and regiospecificity of flavonol specific 3-O-glucosyltransferase (Cp3GT). While the mutant P145T enzyme did not glucosylate anthocyanidins, it did glucosylate flavanones and flavones in addition to retaining activity with flavonols. HPLC was used for product identification and showed mutant P145T glucosylated naringenin at the 7-OH position forming naringenin-7-O-glucoside and flavonols at the 3-OH position. Homology modeling and docking was done to predict the acceptor substrate recognition pattern and models were validated by experimental results. In other related work, …

Restoring Relationship: How The Methodologies Of Wangari Maathai And The Green Belt Movement In Post-Colonial Kenya Achieve Environmental Healing And Women's Empowerment, Casey L. Wagner

Electronic Theses and Dissertations

The effects of the colonial project in Kenya created multi-faceted damages to the land and indigenous people-groups. Using the lens of ecofeminism, this study examines the undergirding structures that produce systems such as colonization that oppress and destroy land, people, and other beings. By highlighting the experience of the Kikuyu people within the Kenyan colonial program, the innovative and ingenious response of Wangari Maathai's Green Belt Movement proves to be a relevant and effective counter to women's disempowerment and environmental devastation in a post-colonial nation. The approach of the Green Belt Movement offers a unique and accessible method for empowering …

Prudery And Perversion: Domination Of The Sexual Body In Middle-Class Men, Women, And Disenfranchised Bodies In Victorian England, Ashley Barnett

Electronic Theses and Dissertations

This research argues that with the rise of the middle-class, Victorian England saw the development of a power model in which middle-class men, middle-class women and disenfranchised bodies of children and lower-class women suffered from the demands of bodily domination. Because the bodily health of middle-class men was believed to represent national health, it was imperative that he dominate his body, particularly with regard to sexual urges. Consequently, the bodies of women with whom he sought sexual release suffered from forms of bodily domination as well. Through an analysis of journals and private writings of those living in Victorian England, …

The Handweavers Of Modern-Day Southern Appalachia: An Ethnographic Case Study, Cathryn F. Washell

Electronic Theses and Dissertations

One of the most prominent traditions associated with the Southern Appalachians is the art of weaving. Extensive research has focused on the history of Appalachian weaving, but there is little on the current weaving community. Today, the region still serves as an axis for weaving, and many practicing weavers, weaving instructors, and learning institutions can be found in Southern Appalachia. The core of this study is the interviews with ten weavers that reside and practice their work in Appalachia. Using concept coding, the transcripts of the interviews led to the development of four major themes that highlight the weavers’ discovery …

Special Collections Newsletter, C.L. Sonnichsen Special Collections Department

UTEP Library

E-newsletter of the Special Collections Department of the UTEP Library.

Insecticide Sensitivity Of Native Chloride And Sodium Channels In A Mosquito Cell Line, Lacey J. Jenson, Troy D. Anderson, Jeffrey R. Bloomquist

Department of Entomology: Faculty Publications

The aim of this study was to investigate the utility of cultured Anopheles gambiae Sua1B cells for insecticide screening applications without genetic engineering or other treatments. Sua1B cells were exposed to the known insecticidal compounds lindane and DIDS, which inhibited cell growth at micromolar concentrations. In patch clamp studies, DIDS produced partial inhibition (69%) of chloride current amplitudes, and an IC50 of 5.1 μM was determined for Sua1B cells. A sub-set of chloride currents showed no response to DIDS; however, inhibition (64%) of these currents was achieved using a low chloride saline solution, confirming their identity as chloride channels. In …

Healthcare Professionals’ Awareness And Knowledge Of Adverse Drug Reactions And Pharmacovigilance, Noor B. Almandil

Saudi Medical Journal

Objectives To document the knowledge of, attitudes toward, and practices of adverse drug reaction (ADR) reporting and pharmacovigilance systems among healthcare professionals. Methods This descriptive cross-sectional study was conducted using a questionnaire. This study took place at King Fahd Hospital of the University (KFHU), Khobar, Kingdom of Saudi Arabia, between April 2015 and April 2016. Healthcare professionals, including physicians, pharmacists, pharmacy technicians, and nurses, were considered eligible and invited to take part in the study. A link to the online questionnaire was sent to each participant via E-mail, and a hard copy was circulated at the hospital after the objectives …

Who Recommends 29 Ways To Stop Surgical Infections And Avoid Superbugs

Saudi Medical Journal

No abstract provided.

Sacrifice At Khirbet Qumran And In The Dead Sea Scrolls: Implications For Understanding The Wilderness Tradition And Penitential Prayers, Kenneth Atkinson

Faculty Publications

No abstract provided.

Kihefo Vocational Center: Kabale, Uganda, Jason Matthew Angerer

Construction Management

Journeyman International (JI) is a non-profit organization which acts as a platform for bringing together volunteer Architects, Designers, Engineers, and Construction Managers with humanitarian projects around the world. Kigezi Healthcare Foundation (KIHEFO) a non-profit NGO located in Kabale, Uganda is a client seeking to build a vocational center to educate the workforce of Uganda. The center will include multi-purpose class rooms, a dining hall, rabbit farm, carpentry shop, and living complex. The Architect on the project was Courtney Wedel from Cal Poly. As the Construction Manager on the project my responsibilities include; Design Assist, Feasibility Analysis, Scheduling, Estimating, and Managing …