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Versatility Of N-Peptidyl And N-Glycopeptidyl Nitroindolines For The Formation Of Peptide/Glycopeptide Acids, Amides, And Thioesters, Luis Alfonso Barrera

Open Access Theses & Dissertations

N-acyl-7-nitroindolines are photoreactive compounds that are known to acylate a number of nucleophiles in inert aprotic solvents under neutral conditions when illuminated at 350 nm. We have assembled a MUC1-derived peptide and Tn or STn-containing MUC1 glycopeptides with a C-terminal photoreactive 7-nitroindoline linker attached to Sieber amide resin by solid phase peptide synThesis using the Fmoc strategy. This type of construction allows for the cleavage of fully protected photoreactive peptides/glycopeptides from the resin with dilute trifluoroacetic acid, or for the direct photorelease of protected peptide/glycopeptide derivatives. Here we demonstrate that N-peptidyl and N-glycopeptidyl 7-nitrindolines can be photochemically converted into their …

Current-Induced Depairing In The Bi₂Te₃/Fete Interfacial Superconductor, M. N. Kunchur, C. L. Dean, N. Shayesteh Moghadam, J. M. Knight, Q. L. He, H. Liu, J. Wang, R. Lortz, I. K. Sou, Alex Gurevich

Physics Faculty Publications

We investigated current induced depairing in the Bi₂Te₃/FeTe topological insulator-chalcogenide interface superconductor. The measured depairing current density provides information on the magnetic penetration depth and superfluid density, which in turn shed light on the nature of the normal state that underlies the interfacial superconductivity.

A Comparison Of Self-Acceptance Of Disability Between Thai Buddhists And American Christians, Roy K. Chen, Wilaiporn Kotbungkair, Alicia D. Brown

School of Rehabilitation Services & Counseling Faculty Publications

Having a disability can significantly change a person’s life in many aspects. Research has shown that people with disabilities collectively have diminished access and fewer opportunities to pursue education, find gainful employment, and engage in intimate relationships. Self-acceptance of disability is, therefore, critical to help build resilience, confidence, and psychological well-being in this population. The purpose of the study was to compare the self-acceptance of disability in international settings, specifically in the context of religions. The sample of the study included 98 Thai Buddhists and 95 American Christians with neuromuscular disorders. Constructs used for the study included demographic characteristics, Hope …

Construction Innovator, Winter 2015

Construction Innovator

No abstract provided.

The Electoral Costs Of Party Agenda Setting: Why The Hastert Rule Leads To Defeat, Jesse Richman

Political Science & Geography Faculty Publications

This study demonstrates that unconditional blocking of bills opposed by a majority of the majority party--as implied by the party cartel model and advocated by former Speaker Dennis Hastert--can produce conditions in which the majority party loses popular support and loses elections. The theoretical analysis and empirical results imply that the use of negative agenda power to block bills is circumscribed by this risk of electoral defeat. As a result, the opportunity for effective negative agenda control is conditional on majority party issue advantage, party polarization, and the distribution of status quo locations. In particular, majority party roll rates should …

Growing South Dakota (Winter 2015), College Of Agriculture &. Biological Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

This issue includes the 2014 SDSU Agricultural Experiment Station Annual Report.

[Page] 2 AES Director’s Message
[Page] 3 Better Beans: Innovative Research Seeks To Increase Soybean’s Nitrogen-Fixing Ability
[Page] 6 Bioprocessing Adds Value: Researchers Turn Agricultural Residue Into Energy Storage Material
[Page] 8 Protecting Water Quality: Conservation Practices Minimize Erosion, Surface Runoff
[Page] 10 Balancing Ag & Wildlife: Cover Crop Food Plots Help Manage Deer Population
[Page] 11 Industry Insight: Beef Consumers Get Information From Websites, Social Media
[Page] 12 Evaluating Efficiency: Swine Nutritional Studies Underway; New Facility Will Allow For Expanded Research
[Page] 14 SDSU Hosts National Ag Leaders …

Adverse Outcome Pathways Can Drive Non‐Animal Approaches For Safety Assessment, N Burden, F Sewell, Me Andersen, A Boobis, Jk Chipman, Mtd Cronin, Th Hutchinson, I Kimber, M Whelan

School of Geography, Earth and Environmental Sciences

AbstractAdverse Outcome Pathways (AOPs) provide an opportunity to develop new and more accurate safety assessment processes for drugs and other chemicals, and may ultimately play an important role in regulatory decision making. Not only can the development and application of AOPs pave the way for the development of improved evidence‐based approaches for hazard and risk assessment, there is also the promise of a significant impact on animal welfare, with a reduced reliance on animal‐based methods. The establishment of a useable and coherent knowledge framework under which AOPs will be developed and applied has been a first critical step towards realizing …

The Effects Of Unequal Compressive/Tensile Moduli Of Composites, M. Meng, H. R. Le, M. J. Rizvi, S. M. Grove

School of Engineering, Computing and Mathematics

Abstract This paper investigates the effects of unequal compressive and tensile moduli of carbon fibre reinforced plastic (CFRP) composites. The basic assumption is based on the statistics that the compressive modulus is a fraction lower than the tensile modulus. Data evaluated by Finite Element Analysis (FEA) model, Classical Laminate Theory (CLT) model, and experiment are used to investigate these effects. The terms of compressive modulus are successfully introduced into the Tsai–Wu failure criterion for the production of failure envelops, into the Classical Beam Theory (CBT) and CLT for the investigation of flexural behaviour as well as the fibre microbuckling model …

Performance Of Graduates In Licensure Examination For Agriculturists In Bicol Region, Philippines, Cynthia L. Dimayuga

Journal of Public Affairs and Development

The study assessed the performance of graduates in Licensure Examination for Agriculturists (LEA) in the different state universities and colleges in Bicol Region, Philippines in 2008 and 2009. Central Bicol State University of Agriculture ranked 1st, Camarines Norte State College ranked 2nd, Catanduanes State College ranked 3rd, Bicol University College of Agriculture and Forestry ranked 4th, Dr. Emilio B. Espinosa, Sr. Memorial State College of Agriculture and Technology ranked 5th, and Sorsogon State College ranked 6th.

Academic variables such as fourth year high school average grade (FYHSG), college general weighted average (CGWA), and the type of preparation tool were found …

Participation Of Beneficiaries In Community Health Care Program: The Case Of Tanghpre Parish, Kachin State, Myanmar, Peter Mahka Myo Aung, Josefina T. Dizon, Maria Ana T. Quimbo, Angelina R. Bustos

Journal of Public Affairs and Development

This study determined the perception on the participation level of village people as beneficiaries of a community health care project, which served as a development strategy in four villages of Tangphre Parish in Kachin State, Myanmar. A total of 62 beneficiaries including one project staff served as respondents of the study. Data were collected through a combination of individual survey and key informant interviews. Results of the survey were analyzed using descriptive statistics.

Results showed that the perceived level of participation was moderate in all phases. Project activities such as health prevention trainings; support for basic needs; and provision of …

Farmer Field School As An Effective Approach In Increasing Farmers’ Knowledge, Skills, And Practices, And In Enhancing Diffusion Of Innovations: Evidences From Selected Rice Farmers In Masalasa, Victoria, Tarlac, Philippines, Glenn Y. Ilar

Journal of Public Affairs and Development

The study assessed the effectiveness of the Farmer Field School (FFS) approach in increasing the knowledge, skills, and practices of selected rice farmers in Barangay Masalasa, Victoria, Tarlac in the Philippines as well as the diffusion of innovations among them. Empirical evidences were obtained from the 24 farmers who attended the FFS on PalayCheck System and 24 non-participating farmers serving as the control group. The FFS provided farmers with new knowledge and skills on the whole PalayCheck System as demonstrated by the FFS graduates having more knowledge on the PalayCheck component-technologies as compared with non-FFS farmers. All the FFS farmers …

Comparative Analysis Of The National And Communal Irrigation Systems’ Water Governance: The Philippines Case, Miriam R. Nguyen, Agnes C. Rola, Rosalie A. Hall, Corazon L. Abansi, Myra E. David

Journal of Public Affairs and Development

Using Saleth and Dinar’s water governance framework, the study characterized irrigators’ associations and examined how they operate and how they are managed. A total of 128 association presidents were surveyed in ten provinces in the Philippines and were asked about their knowledge and perception on the organization, natural resource policies, and water status in the locality.

The National Irrigation Systems (NIS) still has a formal structure as influenced by the National Irrigation Administration (NIA), but it is assuming the characteristics of the Communal Irrigation Systems (CIS) management because of the paradigm shift to participatory irrigation management. The CIS, on the …

Addressing Food Security: Saba Banana And Rootcrops As Alternative Food Staples To Rice In Quezon Province, Philippines, Isabelita M. Pabuayon, Blanquita R. Pantoja, Anselma C. Manila, Mac Lorenz C. Santos

Journal of Public Affairs and Development

The Philippines considers rice self-sufficiency as vital to food security; hence, possible alternative food staples are being identified in case of persistent shortfalls in domestic rice production. This paper explores the potential of Saba (cardava) banana, sweet potato, potato, yam, and cassava as alternative staples for the local communities in the Quezon province, Philippines, which grow all these crops. Socioeconomic surveys of 375 farmers, 82 traders, and 625 consumers were conducted in 2013 but covered crop year 2012. Results showed that Saba banana, sweet potato, and cassava had the highest demand among the five crops based on per capita consumption. …

Community Development Methods Toward Food Security: The System Of Rice Intensification In Zumalai Subdistrict, Covalima, Timor-Leste, Ergilio F. Vicente, Josefina T. Dizon

Journal of Public Affairs and Development

The study was conducted in Zumalai subdistrict, Covalima in Timor-Leste to analyze the contribution of the System of Rice Intensification (SRI) program. The program was implemented through community development methods, namely: community education, community organizing, and community resource management to achieve rice security. Using the Slovin’s formula, 24 farmer-groups from Raimea village and 17 from Tashilin village were selected through draw lot sampling. From each farmer-group, five members were randomly chosen to comprise 205 respondents to participate in the household survey. Data were analyzed through descriptive and inferential statistics.

The findings revealed that majority of the respondents attended various components …

Europeana Sounds And Copyrights: The Need For And Challenges In Licensing Archival Materials, S Schroff

School of Law, Humanities and Social Sciences

No abstract provided.

A Record Of Spontaneous Subduction Initiation In The Izu-Bonin-Mariana Arc, Rj Arculus, O Ishizuka, Ka Bogus, M Gurnis, R Hickey-Vargas, Mh Aljahdali, An Bandini-Maeder, Ap Barth, Pa Brandl, L Drab, Rdm Guerra, M Hamada, F Jiang, K Kanayama, S Kender, Y Kusano, H Li, Lc Loudin, M Maffione, Km Marsaglia, A Mccarthy, S Meffre, A Morris, M Neuhaus, Ip Savov, C Sena, Tfj Iii, Der Land C Van, Gm Yogodzinski, Z Zhang

School of Geography, Earth and Environmental Sciences

No abstract provided.

Boundary And Interface Cfts From The Conformal Bootstrap, Ferdinando Gliozzi, Pedro Liendo, Marco Meineri, Antonio Rago

School of Engineering, Computing and Mathematics

No abstract provided.

Non-Transferrin-Bound Iron Is Associated With Biomarkers Of Oxidative Stress, Inflammation And Endothelial Dysfunction In Type 2 Diabetes, Husam Aljwaid, Desley L. White, Keith J. Collard, A. John Moody, Jonathan H. Pinkney

School of Health Professions

No abstract provided.

Use Of A Seagrass Residency Index To Apportion Commercial Fishery Landing Values And Recreation Fisheries Expenditure To Seagrass Habitat Service., Emma L. Jackson, Siân E. Rees, Catherine Wilding, Martin J. Attrill

School of Biological and Marine Sciences

Where they dominate coastlines, seagrass beds are thought to have a fundamental role in maintaining populations of exploited species. Thus, Mediterranean seagrass beds are afforded protection, yet no attempt to determine the contribution of these areas to both commercial fisheries landings and recreational fisheries expenditure has been made. There is evidence that seagrass extent continues to decline, but there is little understanding of the potential impacts of this decline. We used a seagrass residency index, that was trait and evidence based, to estimate the proportion of Mediterranean commercial fishery landings values and recreation fisheries total expenditure that can be attributed …

Tablet App Halometer For The Assessment Of Dysphotopsia, Pj Buckhurst, Shehzad A. Naroo, Leon N. Davies, Sunil Shah, H Buckhurst, Alec Kingsnorth, Tom Drew, James S. Wolffsohn

School of Health Professions

No abstract provided.

Physical Therapy Provision In Multiple Sclerosis Across Europe: A Regional Lottery?, K Rasova, P Martinkova, M Pavlikova, D Cattaneo, J Jonsdottir, T Henze, I Baert, Asch P Van, C Santoyo, T Smedal, Ag Beiske, M Stachowiak, M Kovalewski, U Nedeljkovic, D Bakalidou, J Alves-Guerreiro, Y Nilsagard, En Dimitrova, M Habek, K Armutlu, C Donze, E Ross, Am Ilie, A Martic, J Freeman, A Romberg, P Feys

School of Health Professions

No abstract provided.

The Socio-Economic Effects Of A Marine Protected Area On The Ecosystem Service Of Leisure And Recreation, Siân E. Rees, Stephen C. Mangi, Caroline Hattam, Sarah C. Gall, Lynda D. Rodwell, Frankie J. Peckett, Martin J. Attrill

School of Biological and Marine Sciences

No abstract provided.

New Insights Into Landslide Processes Around Volcanic Islands From Remotely Operated Vehicle (Rov) Observations Offshore Montserrat, S. F.L. Watt, M. Jutzeler, P. J. Talling, S. N. Carey, R. S.J. Sparks, M. Tucker, A. J. Stinton, J. K. Fisher, D Wall‐Palmer, V. Hühnerbach, S. G. Moreton

School of Geography, Earth and Environmental Sciences

AbstractSubmarine landslide deposits have been mapped around many volcanic islands, but interpretations of their structure, composition, and emplacement are hindered by the challenges of investigating deposits directly. Here we report on detailed observations of four landslide deposits around Montserrat collected by Remotely Operated Vehicles, integrating direct imagery and sampling with sediment core and geophysical data. These complementary approaches enable a more comprehensive view of large‐scale mass‐wasting processes around island‐arc volcanoes than has been achievable previously. The most recent landslide occurred at 11.5–14 ka (Deposit 1; 1.7 km3) and formed a radially spreading hummocky deposit that is morphologically similar to many …

Metals In Boat Paint Fragments From Slipways, Repair Facilities And Abandoned Vessels: An Evaluation Using Field Portable Xrf., Andrew Turner, Sean Comber, Aldous B. Rees, Dimitrios Gkiokas, Kevin Solman

School of Geography, Earth and Environmental Sciences

Paint flaking off abandoned vessels or generated during boat repair is hazardous to human health and wildlife. In this study, a means of screening paint fragments using a field portable-X-ray fluorescence (FP-XRF) spectrometer is described. The technique is capable of delivering rapid, surficial measurements of Ba, Cu, Pb and Zn down to concentrations less than 150 μg g(-1), and Sn and Cr to concentrations of a few hundred μg g(-1). Application of the technique to fragments collected from slipways, yards, hardstandings, abandoned boats and ships undergoing maintenance throughout the EU reveal highly variable concentrations of metals among samples from the …

Visualizing Peripheral Nerve Regeneration By Whole Mount Staining., Xin Peng Dun, David B. Parkinson

Peninsula Medical School

Peripheral nerve trauma triggers a well characterised sequence of events both proximal and distal to the site of injury. Axons distal to the injury degenerate, Schwann cells convert to a repair supportive phenotype and macrophages enter the nerve to clear myelin and axonal debris. Following these events, axons must regrow through the distal part of the nerve, re-innervate and finally are re-myelinated by Schwann cells. For nerve crush injuries (axonotmesis), in which the integrity of the nerve is maintained, repair may be relatively effective whereas for nerve transection (neurotmesis) repair will likely be very poor as few axons may be …

A Robust Bearing Fault Detection And Diagnosis Technique For Brushless Dc Motors Under Non-Stationary Operating Conditions, Wathiq Abed, Sanjay Sharma, Robert Sutton, Amit Motwani

School of Engineering, Computing and Mathematics

No abstract provided.

Neural Network Fault Diagnosis Of A Trolling Motor Based On Feature Reduction Techniques For An Unmanned Surface Vehicle, Wathiq Abed, Sanjay Sharma, Robert Sutton

School of Engineering, Computing and Mathematics

This article presents a novel approach to the diagnosis of unbalanced faults in a trolling motor under stationary operating conditions. The trolling motor being typically of that used as the propulsion system for an unmanned surface vehicle, the diagnosis approach is based on the use of discrete wavelet transforms as a feature extraction tool and a time-delayed neural network for fault classification. The time-delayed neural network classifies between healthy and faulty conditions of the trolling motor by analysing the stator current and vibration. To overcome feature redundancy, which affects diagnosis accuracy, several feature reduction methods have been tested, and the …

Neural Dynamics Of Social Tie Formation In Economic Decision-Making, Nadège Bault, Benjamin Pelloux, Johannes J. Fahrenfort, K. Richard Ridderinkhof, Winden F Van

School of Psychology

No abstract provided.

Detecting Radiation Reaction At Moderate Laser Intensities., Thomas Heinzl, Chris Harvey, Anton Ilderton, Mattias Marklund, Stepan S. Bulanov, Sergey Rykovanov, Carl B. Schroeder, Eric Esarey, Wim P. Leemans

School of Engineering, Computing and Mathematics

We propose a new method of detecting radiation reaction effects in the motion of particles subjected to laser pulses of moderate intensity and long duration. The effect becomes sizable for particles that gain almost no energy through the interaction with the laser pulse. Hence, there are regions of parameter space in which radiation reaction is actually the dominant influence on charged particle motion.

The Hows And Whys Of Face Processing: Level Of Construal Influences The Holistic Processing Of Human Faces., Na Wyer, Tj Hollins, S Pahl

School of Psychology

No abstract provided.