Digital Commons Network^™

Difference Equation For Tracking Perturbations In Systems Of Boolean Nested Canalyzing Functions, Elena S. Dimitrova, Oleg I. Yordanov, Mihaela Teodora Matache

Mathematics Faculty Publications

This paper studies the spread of perturbations through networks composed of Boolean functions with special canalyzing properties. Canalyzing functions have the property that at least for one value of one of the inputs the output is fixed, irrespective of the values of the other inputs. In this paper the focus is on partially nested canalyzing functions, in which multiple, but not all inputs have this property in a cascading fashion. They naturally describe many relationships in real networks. For example, in a gene regulatory network, the statement “if gene A is expressed, then gene B is not expressed regardless of …

The Evolution Of Scientific Productivity Of Junior Scholars, Chun-Hua Tsai, Yu-Ru Lin

Information Systems and Quantitative Analysis Faculty Proceedings & Presentations

Publishing academic work has been recognized as a key indicator for measuring scholars’ scientific productivity and having crucial impact on their future career. However, little has been known about how the majority of researchers progress in publishing papers across disciplines. In this work, using a collection consisting of over five millions academic publications across 15 disciplines, we study how the scientific productivity patterns of junior scholars change across different generations and different domains. Our study results help understand the evolution of the competitive “publish or perish” academic culture.

Abandoned Babies: The Backlash Of South Korea's Special Adoption Act, Sook K. Kim

Washington International Law Journal

South Korea amended its adoption law to reduce the number of foreign adoptions and to keep children with their biological families. However, since the amendment took effect in August 2012, more babies have been abandoned. The amendment (hereinafter the “Special Adoption Act”) created three conditions on birthparents who wish to place their child up for adoption. First, birthparents must wait at least seven days after their child is born before they may consent to placing their child up for adoption. Second, birthparents must receive counseling on the various resources that would be available to them if they choose to raise …

Salvage Brachytherapy In Combination With Interstitial Hyperthermia For Locally Recurrent Prostate Carcinoma Following External Beam Radiation Therapy: A Prospective Phase Ii Study., Andrzej M Kukiełka, Vratislav Strnad, Paul R. Stauffer, Tomasz Dąbrowski, Marcin Hetnał, Damian Nahajowski, Tomasz Walasek, Piotr Brandys, Robert Matys

Department of Radiation Oncology Faculty Papers

Optimal treatment for patients with only local prostate cancer recurrence after external beam radiation therapy (EBRT) failure remains unclear. Possible curative treatments are radical prostatectomy, cryosurgery, and brachytherapy. Several single institution series proved that high-dose-rate brachytherapy (HDRBT) and pulsed-dose-rate brachytherapy (PDRBT) are reasonable options for this group of patients with acceptable levels of genitourinary and gastrointestinal toxicity. A standard dose prescription and scheme have not been established yet, and the literature presents a wide range of fractionation protocols. Furthermore, hyperthermia has shown the potential to enhance the efficacy of re-irradiation. Consequently, a prospective trial is urgently needed to attain clear …

Emg Prosthetic Finger: "Gogo Finger", Omar Garibay, Ernesto Bermudez, Shane O'Neil

Electrical Engineering

No abstract provided.

Using Mobile Cameras To Measure Dye Concentration In Bio-Chemistry Experiments, Jackie Fong, Andrew Lau, Anna Katrina Velasquez

Computer Engineering

Many cutting edge chemistry experiments for high ­throughput assays require measuring colored outputs from specially prepared samples. Absorbance from these samples is usually measured with a specialized piece of equipment that adds to the expense, time, and complexity of obtaining experimental results. To make these experiments more accessible, we looked at developing software to allow cell phones or consumer ­grade USB cameras to measure these experiments and quantify the intensity of the output.

What we have compiled thus far is research regarding several different color spaces and attempted analysis on the many channels of color spaces such as RGB, HSV, …

Math Department Newsletter, 2015, University Of Dayton. Department Of Mathematics

Department of Mathematics Newsletters

No abstract provided.

Psychological And Social Variables Impacting Young Adults Caring For Severely Mentally Ill Mothers, Courtney Gale Deloney

Dissertations

This dissertation study examined the psychological and social functioning of young adults who care for their severely mentally ill mothers; in doing so this study examined the independent variables coping style, perceived stress, quality of life, and resilience. The dependent variables considered were race, socioeconomic status, support group participation, and living in the same household as one’s mother. Young adulthood was examined as a distinct period of human development. The policy of deinstitutionalization led many families to become caregivers for their severely mentally ill relatives. While some knowledge on this exists, little is known about the experiences of young adult …

Tongues Untied Truth Revealed: Body Image, Social Media, Identity Development, And Meaning-Making In Overweight And Obese Black Gay Msm, Amari Ja-Lynn Enam

Dissertations

This phenomenological study explored the meanings attributed to internalized messages about body image within the context of identity development from the perspectives of overweight/obese men of African descent (OMAD) among a group of 6 men who have sex with men (MSM). I was interested in those messages that have been incorporated, adopted, or integrated into OMAD-MSM’s sense of self. Informants shared body image-related experiences from interactions with family, friends, dating/sex partners, and the media/social media.

Academic literature has explained identity development processes among African Americans through various lenses but research has not adequately explored the convergence of multiply oppressed social …

Deprivation And "Deviance": The Disability And Health Experiences Of Women In North Carolina's Prisons, Carrie Griffin Basas, Lisa Peters

North Carolina Law Review

No abstract provided.

Ccl20 Is Elevated During Obesity And Differentially Regulated By Nf-Κb Subunits In Pancreatic Β-Cells, Susan J. Burke, Michael D. Karlstad, Kellie M. Regal, Tim E. Sparer, Danhong Lu, Carrie M. Elks, Ryan W. Grant, Jacqueline M. Stephens, David H. Burk, J. Jason Collier

Faculty Publications

© 2015 Elsevier B.V. Enhanced leukocytic infiltration into pancreatic islets contributes to inflammation-based diminutions in functional β-cell mass. Insulitis (aka islet inflammation), which can be present in both T1DM and T2DM, is one factor influencing pancreatic β-cell death and dysfunction. IL-1β, an inflammatory mediator in both T1DM and T2DM, acutely (within 1. h) induced expression of the CCL20 gene in rat and human islets and clonal β-cell lines. Transcriptional induction of CCL20 required the p65 subunit of NF-κB to replace the p50 subunit at two functional κB sites within the CCL20 proximal gene promoter. The NF-κB p50 subunit prevents CCL20 …

Learning To Teach For Social Justice: Context And Progressivism At Bank Street In The 1930’S, Jaime Grinberg, Katia Paz Goldfarb

Department of Educational Foundations Scholarship and Creative Works

This is a historical case study of the role of contexts in the education of progressive teachers and learning to advance social justice through teaching. The case focuses on how progressive education, progressive schools, and progressive ideas in the US, primarily during the 1930’s influenced a very distinctive program, The Cooperative School for Teachers, which became Bank Street College of Education, in New York City. And in turn how this program came to influence what progressive teacher education could be about. This paper addresses how students at Bank Street developed a sense of relationship between the need to understand and …

Surveillance As Loss Of Obscurity, Woodrow Hartzog, Evan Selinger

Washington and Lee Law Review

No abstract provided.

New Hampshire Water Resources Research Center Annual Technical Report Fy 2014, New Hampshire Water Resources Research Center (Nh Wrrc)

NH Water Resources Research Center Scholarship

No abstract provided.

Countering Insurgency And The Myth Of “The Cause”, Daniel G. Cox, Alex Ryan

Journal of Strategic Security

It is possible for an insurgency to develop from a single cause, for the insurgents to identify and communicate this unifying cause to the population, and for the insurgents to remain steadfastly focused even as counterinsurgents undermine their organization and redress the cause. But often the case that there is no single cause, that popular support is mobilized by appealing to multiple motivations, and that by the time counterinsurgents resolve the initial grievance, the insurgency has found alternative justifications to mobilize popular support. Since insurgent leadership is often competent and adaptive, it would be wise to consider the latter scenario …

Advances In Understanding Carboxysome Assembly In Prochlorococcus And Synechococcus Implicate Csos2 As A Critical Component, Fei Cai, Zhicheng Dou, Susan L. Bernstein, Ryan Leverenz, Eric B. Williams, Sabine Heinhorst, Jessup M. Shively, Gordon C. Cannon, Cheryl A. Kerfeld

Faculty Publications

The marine Synechococcus and Prochlorococcus are the numerically dominant cyanobacteria in the ocean and important in global carbon fixation. They have evolved a CO₂-concentrating-mechanism, of which the central component is the carboxysome, a self-assembling proteinaceous organelle. Two types of carboxysome, α and β, encapsulating form IA and form IB d-ribulose-1,5-bisphosphate carboxylase/oxygenase, respectively, differ in gene organization and associated proteins. In contrast to the β-carboxysome, the assembly process of the α-carboxysome is enigmatic. Moreover, an absolutely conserved α-carboxysome protein, CsoS2, is of unknown function and has proven recalcitrant to crystallization. Here, we present studies on the CsoS2 protein in …

Electron Transmission Through Micrometer Sized Funnelshaped Tapered Glass Capillaries And Electron Micro-Beam Production, Samanthi Jayamini Wickramarachchi

Dissertations

The prime motivation of this work is to understand the fundamental transmission process of an electron beam through a funnel-shaped capillary taking into account its shape together with the energy, angular and time dependence of the transmitted electrons produce a microsized electron beam. The utilized capillaries had inlet/outlet diameters of 800/16 μm, 800/100 μm and lengths of 35 mm. Considerable transmission of 800 and 1000 eV electrons for tilt angles up to 1.5^o and only small transmission for 500 eV electrons was observed for the capillary with the smaller outlet diameter of 16 μm. Incident electrons with energies of …

Journal Assessment Is Not All About Counter Statistics, Lutishoor Salisbury

University Libraries Faculty Publications and Presentations

No abstract provided.

User Engagement And Outreach In Scholarly Communication Issues In The Stem, Education And Behavioral Sciences, Lutishoor Salisbury, Julie Speer, Mel Desart, Brian Quinn

University Libraries Faculty Publications and Presentations

No abstract provided.

An Aggregate Stochastic Model Incorporating Individual Dynamics For Predation Movements Of Anelosimus Studiosus, Alex John Quijano, Michele L. Joyner, Edith Seier, Nathaniel Hancock, Michael Largent, Thomas C. Jones

ETSU Faculty Works

In this paper, we discuss methods for developing a stochastic model which incorporates behavior differences in the predation movements of Anelosimus studiosus (a subsocial spider). Stochastic models for animal movement and, in particular, spider predation movement have been developed previously; however, this paper focuses on the development and implementation of the necessary mathematical and statistical methods required to expand such a model in order to capture a variety of distinct behaviors. A least squares optimization algorithm is used for parameter estimation to fit a single stochastic model to an individual spider during predation resulting in unique parameter values for each …

Iarc Monographs: 40 Years Of Evaluating Carcinogenic Hazards To Humans, Neil E. Pearce, Aaron Blair, Paolo Vineis, Wolfgang Ahrens, Aage Andersom, Josep M. Anto, Bruce K. Armstrong, Andrea A. Baccarelli, Frederick A. Beland, Amy Berrington, Pier Alberto Bertazzi, Linda S. Birnbaum, Ross C. Brownson, John R. Bucher, Kenneth P. Cantor, Elisabeth Cardis, John W. Cherrie, David C. Christiani, Pierluigi Cocco, David Coggon, Pietro Comba, Paul A. Demers, John M. Dement, Jeroen Douwes, Ellen A. Eisen, Lawrence S. Engel, Richard A. Fenske, Lora E. Fleming, Tony Fletcher, Elizabeth Fontham, Francesco Forastiere, Rainer Frentzel-Beyme, Lin Fritschi, Michel Gerin, Marcel Goldberg, Philippe Grandjean, Tom K. Grimsrud, Per Gustavsson, Andy Haines, Patricia Hartge, Johnni Hansen, Michael Hauptmann, Dick Heederik, Kari Hemminki, Denis Hemon, Irva Hertz-Picciotto, Jane A. Hoppin, James Huff, Bengt Jarvholm, Daehee Kang, Margaret R. Karagas

Dartmouth Scholarship

Background: Recently, the International Agency for Research on Cancer (IARC) Programme for the Evaluation of Carcinogenic Risks to Humans has been criticized for several of its evaluations, and also for the approach used to perform these evaluations. Some critics have claimed that failures of IARC Working Groups to recognize study weaknesses and biases of Working Group members have led to inappropriate classification of a number of agents as carcinogenic to humans.

Objectives: The authors of this Commentary are scientists from various disciplines relevant to the identification and hazard evaluation of human carcinogens. We examined criticisms of the IARC classification process …

The Amaranth (Amaranthus Hypochondriacus) Genome: Genome, Transcriptome And Physical Map Assembly, Jared William Clouse

Theses and Dissertations

Amaranthus hypochondriacus is an emerging pseudo-cereal native to the New World which has garnered increased attention in recent years due to its nutritional quality, in particular its seed protein, and more specifically its high levels of the essential amino acid lysine. It belongs to the Amaranthaceae family, is an ancient paleotetraploid that shows amphidiploid inheritance (2n=32), and has an estimated genome size of 466 Mb. Here we present a high-quality draft genome sequence of the grain amaranth A. hypochondriacus. The genome assembly consisted of 377 Mb in 3,518 scaffolds with an N50 of 371 kb. Repetitive element analysis predicted that …

Exceptionally High Levels Of Genetic Diversity In Wheat Curl Mite (Acari: Eriophyidae) Populations From Turkey, W. Szydło, Gary L. Hein, E. Denizhan, A. Skoracka

Department of Entomology: Faculty Publications

Recent research on the wheat curl mite species complex has revealed extensive genetic diversity that has distinguished several genetic lineages infesting bread wheat (Triticum aestivum L.) and other cereals worldwide. Turkey is the historical region of wheat and barley (Hordeum vulgare L.) domestication and diversification. The close relationship between these grasses and the wheat curl mite provoked the question of the genetic diversity of the wheat curl mite in this region. The scope of the study was to investigate genetic differentiation within the wheat curl mite species complex on grasses in Turkey. Twenty-one wheat curl mite populations from …

Differential Receptors For Advanced Glycation End-Products (Rage) Expression In Preeclampsia, Intrauterine Growth Restriction And Gestational Diabetes, Kristen Lena Alexander

Theses and Dissertations

Preeclampsia (PE), intrauterine growth restriction (IUGR) and gestational diabetes (GDM) increase the risk of maternal and fetal morbidity and mortality. The roles of Advanced Glycation End-products (AGEs) are already well documented concerning inflammation, hypoxia and oxidative stress. AGEs bind to its receptor, Receptor for Advanced Glycation End-products (RAGE), and activate an inflammatory pathway. This pathway alters the efficacy of invasive trophoblast cells and in the placenta and can result in placental dysfunction. We hypothesized that the placental dysfunction found in PE, IUGR, and GDM resulted from an over activation of the RAGE-mediated inflammatory pathway. Using human placental samples, we found …

Adolescents' Perceptions Of Homophobic Language: Implications For Bullying Prevention, Benjamin M. Bailey

Theses and Dissertations

Large scientific studies have recognized homophobic language as a national concern (American Association of University Women [AAUW], 2001; Kosciw, Greytak, Diaz, & Bartkiewicz, 2010). Concerning perceptions of homophobic language use, quantitative studies were mostly conducted in specific areas of the United States and qualitative studies have largely approached the issue with the theory of masculinity. The current study proposed to approach the study actively challenging all assumptions about homophobic language use. This study assimilated 20 adolescents' perceptions of homophobic language, using a hermeneutic qualitative methodology. This study found that in addition to policing masculinity, homophobic language was used to police …

The Effects Of Inhibiting Wnt Secretion And Activity On Cranial And Neural Development, Julie Louise Hulet

Theses and Dissertations

Wnt signaling has been shown to have several roles in the development of sensory neurons, particularly in the ophthalmic portion of the trigeminal nerve. Many of these studies have relied on the conclusion that Wnt is necessary but not sufficient for the induction and maintenance of the neural precursor cells that develop in the ophthalmic placode. Wnt had been inhibited in the ophthalmic placode using a dominant negative t-cell factor (TCF) and resulted in the loss of Pax3 expression (indicative of undifferentiated placode cells) in all targeted cells, suggesting a loss of specification/commitment of these cells to the sensory neuron …

The Antioxidant And Dna Repair Capacities Of Resveratrol, Piceatannol, And Pterostilbene, Justin Ryan Livingston

Theses and Dissertations

Lifestyle diseases represent a large burden on developed societies and account for much morbidity worldwide. Research has shown that eating a diet rich in fruit and vegetables helps to ameliorate and prevent some of these diseases. Antioxidants found in fruits and vegetables may provide a substantial benefit in reducing disease incidence. This thesis examines the antioxidant properties of resveratrol, piceatannol, and pterostilbene, and the ability of Burkitt's Lymphoma (Raji) cells to uptake these three antioxidants. It also studies the effect of the antioxidants in protecting against DNA damage and their role in DNA repair following oxygen radical exposure in Raji …

Investigation Of Parameters Affecting The Nanoinjection Of Hela 229 Cancer Cells, Tyler E. Lewis

Theses and Dissertations

The ability to deliver sequences of DNA and other molecular loads across the membrane of a cell and into its nucleus is an area of interest in the medical community. One of its many applications is that of gene therapy. In contrast to other forms of treatment, gene therapy seeks to treat diseases at the cellular level. The success of these treatments depends on the technologies for cell transfection that are available. Physical methods are sometimes able to overcome poor efficiencies of chemical methods and the safety concerns of viral methods, but are usually impractical due to the limited number …

Assessing Validity Of A Screener For Social, Emotional, And Behavioral Concerns: Analyzing Gender Differences In A Middle School Population, Kimberly Lowe

Theses and Dissertations

Systematic screening for social, emotional, and behavioral concerns (SEBC) identifies at-risk students and provides information to guide interventions that may prevent negative outcomes (Glover & Albers, 2006; Kauffman, 1999; Severson, Walker, Hope-Dolittle, Katochwill, & Gresham, 2007). However, the screening process may be influenced by the gender of the student (Young, Sabbah, Young, Reiser, & Richardson, 2010). This study further examined the influence of student gender on screening by assessing the congruency of gates one and two of a screening process based on student gender. Participants included 59 middle school teachers who nominated at-risk students on the Teacher Nomination Form (TNF; …

Cigarette Smoke Increases Cardiomyocyte Ceramide Accumulation And Inhibits Mitochondrial Respiration, Trevor Stanley Tippetts

Theses and Dissertations

Cigarette smoking is a common and lethal worldwide habit, with considerable mortality stemming from its deleterious effects on heart function. While current theories posit altered blood lipids and fibrinogen metabolism as likely mediators, none have explored the role of the sphingolipid ceramide in exacerbating heart function with smoke exposure. Ceramide production is a consequence of cigarette smoke in the lung, and considering ceramide's harmful effects on mitochondrial function, we sought to elucidate the role of ceramide in mediating smoke-induced altered heart mitochondrial respiration. Lung cells were exposed to cigarette smoke extract and heart cells were exposed to the lung-cell conditioned …