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Mixed Waste Landfill Annual Long-Term Monitoring & Maintenance Report, April 2014-March 2015 For Sandia National Laboratories/New Mexico, Epa Id Number Nm5890110518 June 2015, Sandia National Laboratories/Nm, U.S. Department Of Energy

Facilities-Units

The Department of Energy/National Nuclear Security Administration (DOE/NNSA) and Sandia Corporation submitted the Mixed Waste Landfill (MWL) Annual Long-Term Monitoring and Maintenance Report for the April 2014 through March 2015 reporting period to the New Mexico Environment Department (NMED). This report satisfies the requirements of Section 4.8.1 of the MWL Long-Term Monitoring and Maintenance Plan (LTMMP) for documentation of all monitoring, inspection, and maintenance/repair activities conducted during each reporting period. The annual reporting periods run from April 1 to March 31. The MWL is a 2.6-acre Solid Waste Management Unit (SWMU 76) which has undergone corrective action. The MWL is …

Effects Of Pringle Maneuver And Partial Hepatectomy On The Pharmacokinetics And Blood–Brain Barrier Permeability Of Sodium Fluorescein In Rats, Mohammad K. Miah, Imam H. Shaik, Ulrich Bickel, Reza Mehvar

Pharmacy Faculty Articles and Research

Liver diseases are known to affect the function of remote organs. The aim of the present study was to investigate the effects of Pringle maneuver, which results in hepatic ischemia–reperfusion (IR) injury, and partial hepatectomy (Hx) on the pharmacokinetics and brain distribution of sodium fluorescein (FL), which is a widely used marker of blood–brain barrier (BBB) permeability. Rats were subjected to Pringle maneuver (total hepatic ischemia) for 20 min with (HxIR) or without (IR) 70% hepatectomy. Sham-operated animals underwent laparotomy only. After 15 min or 8 h of reperfusion, a single 25-mg/kg dose of FL was injected intravenously and serial …

Na+/K+-Atpase α1 Mrna Expression In The Gill And Rectal Gland Of The Atlantic Stingray, Dasyatis Sabina, Following Acclimation To Increased Salinity Physiology, Andrew N. Evans, Faith N. Lambert

Faculty Publications

Background: The salt-secreting rectal gland plays a major role in elasmobranch osmoregulation, facilitating ion balance in hyperosmotic environments in a manner analogous to the teleost gill. Several studies have examined the central role of the sodium pump Na⁺/K⁺-ATPase in osmoregulatory tissues of euryhaline elasmobranch species, including regulation of Na⁺/K⁺-ATPase activity and abundance in response to salinity acclimation. However, while the transcriptional regulation of Na⁺/K⁺-ATPase in the teleost gill has been well documented the potential for mRNA regulation to facilitate rectal gland plasticity during salinity acclimation in elasmobranchs …

The Effects Of Arginine Vasopressin On Maternal Behavior And Aggression In Peromyscus Californicus Mothers, Nathaniel Ng

Honors Projects

Research studies since the 1950s have shown that a chemical within the brain called arginine vasopressin (AVP) is associated with the modulation of many different social behaviors in mammals. Some of these behaviors are related to parenting, such as parental care initiation, aggression, social recognition, depression and anxiety. Understanding the physiology behind AVP regulation could allow for the creation of new therapies for treating human social disorders, such as using an AVP receptor antagonist to attenuate anxiety. This project examines how neural injections of AVP and an AVP receptor antagonist affect both maternal care and aggression in female Peromyscus californicus …

Treating Trauma: The Efficacy Of Emdr As A Treatment For Ptsd, Grace S. Crawford

Honors Projects

This literature review examines the efficacy of Eye Movement Desensitization and Reprocessing (EMDR) relative to other evidence-based treatments for Posttraumatic Stress Disorder (PTSD), such as Prolonged Exposure (PE) and Cognitive Processing Therapy (CPT). The paper explores the problem of PTSD; outlines the history, theory, and initial trials of EMDR; and examines five randomized controlled trials which compare EMDR to PE or CPT. Results suggest that neither treatment model produces significantly greater reductions in PTSD symptoms, though there is some evidence that EMDR may be better tolerated and produce desired results faster than other treatments.

Narcissism Is Associated With Weakened Frontostriatal Connectivity: A Dti Study, David S. Chester, Donald R. Lynam, David K. Powell, C. Nathan Dewall

Department of Psychological Sciences Faculty Publications

Narcissism is characterized by the search for affirmation and admiration from others. Might this motivation to find external sources of acclaim exist to compensate for neurostructural deficits that link the self with reward? Greater structural connectivity between brain areas that process self-relevant stimuli (i.e. the medial prefrontal cortex) and reward (i.e. the ventral striatum) is associated with fundamentally positive self-views. We predicted that narcissism would be associated with less integrity of this frontostriatal pathway. We used diffusion tensor imaging to assess the frontostriatal structural connectivity among 50 healthy undergraduates (32 females, 18 males) who also completed a measure of grandiose …

Estimates Of Micro-, Nano-, And Picoplankton Contributions To Particle Export In The Northeast Pacific, B. L. Mackinson, S. B. Moran, M. W. Lomas, Gillian M. Stewart, R. P. Kelly

Publications and Research

The contributions of micro-, nano-, and picoplankton to particle export were estimated from measurements of size-fractionated particulate 234Th, organic carbon, and phytoplankton indicator pigments obtained during five cruises between 2010 and 2012 along Line P in the subarctic northeast Pacific Ocean. Sinking fluxes of particulate organic carbon (POC) and indicator pigments were calculated from 234Th;238U disequilibria and, during two cruises, measured by a sediment trap at Ocean Station Papa. POC fluxes at 100m ranged from 0.65 to 7.95 mmolm2 d1, similar in magnitude to previous results at Line P. Microplankton pigments dominate indicator pigment fluxes (averaging 6919% of total pigment …

Membrane Proximal Ectodomain Cleavage Of Muc16 Occurs In The Acidifying Golgi/Post-Golgi Compartments., Srustidhar Das, Prabin D. Majhi, Mona H. Al-Mugotir, Satyanarayana Rachagani, Paul Sorgen, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

MUC16, precursor of the most widely used ovarian cancer biomarker CA125, is up regulated in multiple malignancies and is associated with poor prognosis. While the pro-tumorigenic and metastatic roles of MUC16 are ascribed to the cell-associated carboxyl-terminal MUC16 (MUC16-Cter), the exact biochemical nature of MUC16 cleavage generating MUC16-Cter has remained unknown. Using different lengths of dual-epitope (N-terminal FLAG- and C-terminal HA-Tag) tagged C-terminal MUC16 fragments, we demonstrate that MUC16 cleavage takes place in the juxta-membrane ectodomain stretch of twelve amino acids that generates a ~17 kDa cleaved product and is distinct from the predicted sites. This was further corroborated by …

Investigations Of The Air-Water Interface: A Structural Analysis Of Metallic Surface Films And Aquatic Surface Films By Comparative Microscopy, Randall William Smith

Dissertations and Theses

The air-water interface is an important natural boundary layer that has been neglected as an area of environmental field research. This study establishes that comparative microscopy can be an effective environmental method, and establishes that the term metallic surface films, is a more accurate descriptor than iron oxide surface films. This research shows that surface films are complex, often with layered structure, serve as habitat for significant biota, and act as a point of mineralization to several transition metal elements including manganese, iron, copper, nickel and zinc. This study demonstrates that surface films form under several conditions and can have …

Localized Ecological And Educational Effects Of Environmental Service-Learning In Portland, Oregon, Steven Matthew Braun

Dissertations and Theses

Environmental service-learning is an intentional educational experience(s) wherein learners engage in meaningful activities designed to serve the environment. Environmental service-learning activities vary according to their learning and service goals and include ecomanagement, persuasion, legal action, economic action and political action. The purpose of this mixed methods research was to explore the ecological and educational impacts of grades 6-12 environmental education, with special attention to environmental service-learning throughout Portland, Oregon.

Ecological impacts considered restoration and conservation outcomes of several environmental service-learning programs including plant communities, soils, litter removal and trail maintenance. Educational outcomes considered aspects of environmental literacy including locus of …

Gifted Black And Biracial Students At A Predominantly White Gifted School, Clair Elizabeth Pople

Dissertations and Theses

The underrepresentation of gifted Black and Biracial students is a pervasive problem in and of itself, and indicates a much larger struggle of disproportionality of Black and Biracial students who are not called upon or supported in efforts to meet their academic potential. Therefore, an evaluation of the inequity generated by gifted education is warranted. It is true that the majority of gifted programs are often predominantly White. Accordingly, Black and Biracial students who qualify for gifted programs may face unique challenges in their development of racial identity and their socio-emotional health.

Using ethnographic techniques, this case study explored the …

The Varying Role Of Water Column Nutrient Removal Along River Continua In Contrasting Landscapes, Alexander J. Reisinger, Jennifer L. Tank, Emma J. Rosi-Marshall, Robert O. Hall Jr, Michelle A. Baker

Biology Faculty Publications

Nutrient transformation processes such as assimilation, dissimilatory transformation, and sorption to sediments are prevalent in benthic zones of headwater streams, but may also occur in the water column. The river continuum concept (RCC) predicts that water column processes become increasingly important with increasing stream size. We predicted that water column nutrient uptake increases with stream size, mirroring carbon/energy dynamics predicted by the RCC. We measured water column uptake of ammonium ( NH+4NH4+ ), nitrate ( NO−3NO3− ), and soluble reactive phosphorus (SRP) in 1st through 5th order stream and river reaches (discharge: 50–68,000 L s−1) in three watersheds ranging from …

"Do You Even Lift Bro? "An Investigation Of The Male Viewer's Response To Idealized Body Images In Competitive Reality Television., Caitlin Marie Shaffer

Theses and Dissertations

This study investigates the influence of exposure to idealized body images on competitive reality television shows, specifically the effects on men and their body satisfaction, including a drive for masculinity and a drive for muscularity, as well as the perception of a potential partner. An overwhelming amount of research on the effects on women exposed to idealized images has been completed by previous researchers, but men have been disregarded in comparison regarding this topic. Furthermore, this study will rely on social comparison theory and cultivation theory as theoretical lenses to analyze how male viewers respond to idealized images of males …

Expression, Localization, And Kinetic Characterization Of The Phospholipid Biosynthesis Enzyme Ctp: Phosphocholine Cytidylyltransferase From The Protozoan Parasite Leishmania Major, Justin Daniel Theodore Lange

Theses and Dissertations

The eukaryotic parasite Leishmania is the causative agent of the disease leishmaniasis. L. major is the most common of 21 species that causes visceral leishmaniasis in humans, and 30 that cause the same disease in other mammals. Visceral leishmaniasis causes fever, weight loss, and over a short amount of time, multiple organ failure, and has a 100% mortality rate within 2 years. This makes it the second largest parasitic killer in the world behind malaria. Over 90% of the worldâ??s cases of visceral leishmaniasis have been reported in underdeveloped countries of India, Bangladesh, Nepal, Sudan, Ethiopia and Brazil, with 500,000 …

The Clinical Utility Of The Adult Attachment Projective Picture System: A Clinician's Perspective, Ashley Gunterman

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The Adult Attachment Projective Picture System (AAP) is the first performance-based measure of adult attachment to be developed. The purpose of the measure is to provide a clinical understanding of an adult client's attachment status and associated coping mechanisms. The AAP is a relatively new measure that has yet to be examined from a utility perspective. In the current study, seven psychologists completed a structured survey in order to identify their perspectives of the AAP and its utility as a clinical instrument. A phenomenological qualitative analysis of the data was conducted to derive themes about the AAP and its clinical …

Health Coaching For Chronic Disease Management: A Program Evaluation Conducted At Denver Health Managed Care, Adam Altschuh

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

The purpose of this study is to evaluate health coaching at Denver Health Managed Care Center. We evaluated patients with diabetes and obesity who received a telephonic, motivational-interviewing intervention. Our hypothesis was that patients who received health coaching would have improved health outcomes compared to patients who received standard medical care alone. This research benefits this specific program in clarifying effectiveness (i.e. improvement in health and efficiency, indicated by length of treatment). Health coaching is a growing area of study. This research also adds to a broader conversation about what professionals best serve in the role of health coaches, what …

Feature Selection In Credit Scoring- A Quadratic Programming Approach Solving With Bisection Method Based On Tabu Search, Jun Huang

Theses and Dissertations

Credit risk is one of the most important topics in the risk management. Meanwhile, it is the major risk of banks and financial institutions encountered as claimed by the Basel capital accord. As a form of credit risk measurement, credit scoring is the credit evaluation process to reduce the current and expected risk of a customer being bad credit. The credit scoring models usually use a set of features to predict the credit status, good credit (unlikely to default) and bad credit (more likely to default), of the applicants. However, with the fast growth in the credit industry and facilitation …

Something To Fear: Perception Of Defining Characteristics Of Animals, Evaluation Of Animals, And The Moderating Role Of Speciesism, Allison Elaine Waters

Theses and Dissertations

Speciesism, a form of prejudice wherein a person gives or takes value away from an organism based upon how he or she categorizes living things, is most likely a form of flexible evolutionary adaptation. However, with increasing awareness of humanity's impact on the environment and growing morality, speciesism is increasingly becoming a disadvantage. Speciesism can be reflected in actions from unethical breeding habits to outright attacks on certain animals. The purpose of this study was to examine if altering the physical appearance of animals affects the person's attitudes towards those animals. It was hypothesized that altering physical characteristics of some …

Analysis Of The Microbial Community Along Three Sites Of The Rio Grande By Denaturing Gradient Gel Electrophoresis, Rebeca Imelda Castro

Theses and Dissertations

ABSTRACT Analysis of the Microbial Community of Three Sites Along the Rio Grande by Denaturing Gradient Gel Electrophoresis (May 2014) Rebeca Imelda Castro, B. A., Texas A & M International University; Chair of Committee: Dr. Monica Mendez In the last decades, the increase in population growth and differences in enforcement regulations on both sides of the Rio Grande may have affected the bacterial composition as a result of effluent discharges, industrial waste, raw sewage outfalls, and agricultural runoff. The purpose of this study was to compare structural differences in the microbial communities of the Rio Grande-Rio Bravo waters based on …

A Predicted Protein Interactome Identifies Conserved Global Networks And Disease Resistance Subnetworks In Maize, Bryan Musungu, Deepak Bhatnagar, Robert L Brown, Ahmad M Fakhoury, Matt Geisler

Publications

Interactomes are genome-wide roadmaps of protein-protein interactions. They have been produced for humans, yeast, the fruit fly, and Arabidopsis thaliana and have become invaluable tools for generating and testing hypotheses. A predicted interactome for Zea mays (PiZeaM) is presented here as an aid to the research community for this valuable crop species. PiZeaM was built using a proven method of interologs (interacting orthologs) that were identified using both one-to-one and many-to-many orthology between genomes of maize and reference species. Where both maize orthologs occurred for an experimentally determined interaction in the reference species, we predicted a likely interaction in maize. …

Fast And Sensitive Genome-Hashing Software And Its Application In Using Ngs As A Detection Agent For Bacterial Presence In Oral Metagenomic Samples, Paul Michael Gontarz

Dissertations

Next generation sequencing has increased the throughput of sequenced DNA into the range of billions of nucleotides sequenced per day. With the increased speed of DNA sequencing and the short length of reads produced by next generation sequencers, a significant challenge has been created in quickly and accurately assembling the hundreds of millions of short reads created by modern sequencing instruments into their full genomic sequences. With the increase in throughput in next generation sequencing and the decrease in time and cost to perform DNA sequencing, novel applications for DNA sequencing are being considered. Among them is a methodology by …

Nine Faculty Members Named Winners Of The 2015 Dean's Excellence Awards, Kendra Carter

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No abstract provided.

Sweatt Named Interim Director Of Civitan International Research Center, Dorothy Efird

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No abstract provided.

Sibs, Paradigm Programs Introduce Undergraduates To Biomedical Research, Dorothy Efird

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No abstract provided.

Temperature Dependent Surface Reconstruction Of Freely Suspended Films Of 4-N-Heptyloxybenzylidene-4-N-Heptylaniline, Daniel E. Martinez Zambrano

Lawrence University Honors Projects

Surfaces of freely suspended thick films of 4-n-heptyloxybenzylidene-4-n-heptylaniline (7O.7) in the crystalline-B phase have been imaged using non-contact mode atomic force microscopy. Steps are observed on the surface of the film with a height of 3.0 +/- 0.1 nm corresponding to the upright molecular length of 7O.7. In addition, we find that the step width varies with temperature between 56 and 59 degrees C. The steps are many times wider than the molecular length, suggesting that the steps are not on the surface but instead originate from edge dislocations in the interior. Using a strain model for liquid crystalline layers …

Mitochondrial Ion Channels In Cancer Transformation, Stephen M. Madamba, Kevin N. Damri, Laurent M. Dejean, Pablo M. Peixoto

Publications and Research

Cancer transformation involves reprograming of mitochondrial function to avert cell death mechanisms, monopolize energy metabolism, accelerate mitotic proliferation, and promote metastasis. Mitochondrial ion channels have emerged as promising therapeutic targets because of their connection to metabolic and apoptotic functions. This mini review discusses how mitochondrial channels may be associated with cancer transformation and expands on the possible involvement of mitochondrial protein import complexes in pathophysiological process.

2015-06-04, Morehead State Board Of Regents

Morehead State Board of Regents Agenda Books and Meeting Minutes

No abstract provided.

The Lifecycle Of The Germinosome, A Bacillus Subtilis Spore Germination Protein Complex, Anthony J. Troiano Jr

Doctoral Dissertations

Fluorescent fusions to germination proteins of Bacillus subtilis were shown to colocalize into a single focus termed the germinosome in sporulating and germinating spores, but not in outgrowing spores. In sporulating cultures, fluorescent foci are seen immediately upon fluorescent signal detection, ~3 hours before dipicolinic acid uptake, and in fluorescent strains with sspA-lacZ fusions, nearly in parallel with the accumulation of β- galactosidase activity. Furthermore, GerD-GFP self-associated in germinant receptor (GR) null strains, as well as in wild-type Bacillus subtilis, and facilitated germinosome formation in live Escherichia coli when expressed with gerAA-mCherry. These findings suggest the germinosome is made …

Factors Constraining The Reproductive Output Of Baptisia Alba Macrophylla, Ashley Morgan Hembrough

Theses and Dissertations

Baptisia alba macrophylla, a native, herbaceous perennial legume, produces inflorescences with a large number of flowers, yet matures relatively few fruits. We hypothesized that the number of seeds matured by B. alba macrophylla is maximized based on resource availability at each stage of development, but this optimal number is further compromised by extrinsic factors including pollen limitation and pre-dispersal seed predation by the weevils Apion rostrum and Tychius sordidus. To test this hypothesis, we conducted a field experiment at two sites: (i) the John English Prairie, located in Hudson, IL, and also (ii) the Sugar Grove Nature Center and Funks …

Identity And Investment In The Community Esl Classroom, Jennifer Marie Sacklin

Dissertations and Theses

After Norton Peirce's (1995, Norton, 2000) groundbreaking work in conceptualizing identity as "multiple, changing, and contradictory," many researchers have explored language learners' identities. However, few studies of identity have been conducted within the "overlooked and understudied" (Mathews-Aydinli, 2008) context of adult community ESL (English as a Second Language), and even fewer studies have focused on LESLLA (low-educated second language and literacy acquisition) learners in mainstream community ESL programs.

This thesis, based on a case study of an adult LESLLA learner in a community ESL class, analyzes how this student's identity, the social context of her life, and the classroom space …