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2015

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Two-Dimensional Dynamics Model Of The Lower Limb To Include Viscoelastic Knee Ligaments, Eduardo Granados Aug 2015

Two-Dimensional Dynamics Model Of The Lower Limb To Include Viscoelastic Knee Ligaments, Eduardo Granados

Theses and Dissertations - UTB/UTPA

A dynamic, 2D, anatomical knee joint model has been developed to simulate knee reactions to external input forces. A deformable contact area approach is used to find contact forces and moments, and a method of applying nonlinear viscoelastic ligament strain rate response was also developed and implemented on the model to account for the effects of viscoelasticity on the ligament fibers. The ligaments were then tested for various deficiencies to identify their effects on the natural frequency of the knee. Internal knee forces from ligaments, muscles, and contacting surfaces are modeled and then numerically found for different exercises. Static and …


Contrasting Demographic History And Gene Flow Patterns Of Two Mangrove Species On Either Side Of The Central American Isthmus, Ivania Cerón-Souza, Elena G. Gonzalez, Andrea E. Schwarzbach, Dayana E. Salas-Leiva, Elsie Rivera-Ocasio, Nelson Toro-Perea, Eldredge Bermingham, W Owen Mcmillan Aug 2015

Contrasting Demographic History And Gene Flow Patterns Of Two Mangrove Species On Either Side Of The Central American Isthmus, Ivania Cerón-Souza, Elena G. Gonzalez, Andrea E. Schwarzbach, Dayana E. Salas-Leiva, Elsie Rivera-Ocasio, Nelson Toro-Perea, Eldredge Bermingham, W Owen Mcmillan

Health & Biomedical Sciences Faculty Publications

Comparative phylogeography offers a unique opportunity to understand the interplay between past environmental events and life-history traits on diversification of unrelated but co-distributed species. Here, we examined the effects of the quaternary climate fluctuations and palaeomarine currents and present-day marine currents on the extant patterns of genetic diversity in the two most conspicuous mangrove species of the Neotropics. The black (Avicennia germinans, Avicenniaceae) and the red (Rhizophora mangle, Rhizophoraceae) mangroves have similar geographic ranges but are very distantly related and show striking differences on their life-history traits. We sampled 18 Atlantic and 26 Pacific locations for A. germinans (N = …


Estimating The Reproducibility Of Psychological Science, Alexander A. Aarts, Et Al, Stephanie C. Lin Aug 2015

Estimating The Reproducibility Of Psychological Science, Alexander A. Aarts, Et Al, Stephanie C. Lin

Research Collection Lee Kong Chian School Of Business

Reproducibility is a defining feature of science, but the extent to which it characterizes current research is unknown. We conducted replications of 100 experimental and correlational studies published in three psychology journals using high-powered designs and original materials when available. Replication effects were half the magnitude of original effects, representing a substantial decline. Ninety-seven percent of original studies had statistically significant results. Thirty-six percent of replications had statistically significant results; 47% of original effect sizes were in the 95% confidence interval of the replication effect size; 39% of effects were subjectively rated to have replicated the original result; and if …


Historical Comparisons Reveal Multiple Drivers Of Decadal Change Of An Ecosystem Engineer At The Range Edge, Lb Firth, N Mieszkowska, Lm Grant, Le Bush, Et Al Aug 2015

Historical Comparisons Reveal Multiple Drivers Of Decadal Change Of An Ecosystem Engineer At The Range Edge, Lb Firth, N Mieszkowska, Lm Grant, Le Bush, Et Al

School of Geography, Earth and Environmental Sciences

Biogenic reefs are important for habitat provision and coastal protection. Long-term datasets on the distribution and abundance of Sabellaria alveolata (L.) are available from Britain. The aim of this study was to combine historical records and contemporary data to (1) describe spatiotemporal variation in winter temperatures, (2) document short-term and long-term changes in the distribution and abundance of S. alveolata and discuss these changes in relation to extreme weather events and recent warming, and (3) assess the potential for artificial coastal defense structures to function as habitat for S. alveolata. A semi-quantitative abundance scale (ACFOR) was used to compare broadscale, …


Tail Event Driven Asset Allocation: Evidence From Equity And Mutual Funds Markets, Wolfgang Karl Hardle, David K. C. Lee, Sergey Nasekin, Xinwen Ni, Alla Petukina Aug 2015

Tail Event Driven Asset Allocation: Evidence From Equity And Mutual Funds Markets, Wolfgang Karl Hardle, David K. C. Lee, Sergey Nasekin, Xinwen Ni, Alla Petukina

Research Collection Lee Kong Chian School Of Business

The correlation structure across assets and opposite tail movements are essential to the asset allocation problem, since they determine the level of risk in a position. Correlation alone is not informative on the distributional details of the assets. Recently introduced TEDAS -Tail Event Driven ASset allocation approach determines the dependence between assets at tail measures. TEDAS uses adaptive Lasso based quantile regression in order to determine an active set of negative nonzero coefficients. Based on these active risk factors, an adjustment for intertemporal correlation is made. In this research authors aim to develop TEDAS, by introducing three TEDAS modifications differing …


The Roles Of Human Cytomegalovirus Us27 Gene Product During Virus Infection, Carolyn C. Tu Aug 2015

The Roles Of Human Cytomegalovirus Us27 Gene Product During Virus Infection, Carolyn C. Tu

Master's Theses

Human cytomegalovirus (HCMV) is a widespread pathogen that causes lifelong latent infection. Successful persistence of HCMV in healthy individuals involves extensive manipulation of host cellular functions and immune responses. HCMV encodes four genes for putative G protein-coupled receptors (GPCRs): US27, US28, UL33, and UL78. The US28 gene product is a functional chemokine receptor that exhibits a variety of signaling outcomes. In contrast, the US27 gene product is an orphan with no known chemokine ligands. We have found that US27 triggers several biological effects: increased cellular proliferation, changes in gene expression, and enhanced signaling of cellular chemokine receptor CXCR4. Enhanced cell …


Nmr-Based Structural Analysis Of Threonylcarbamoyl-Amp Synthase And Its Substrate Interactions, Kimberly A. Harris, Benjamin G. Bobay, Kathryn L. Sarachan, Alexis F. Sims, Yann Bilbille, Christopher Deutsch, Dirk Iwata-Reuyl, Paul F. Agris Aug 2015

Nmr-Based Structural Analysis Of Threonylcarbamoyl-Amp Synthase And Its Substrate Interactions, Kimberly A. Harris, Benjamin G. Bobay, Kathryn L. Sarachan, Alexis F. Sims, Yann Bilbille, Christopher Deutsch, Dirk Iwata-Reuyl, Paul F. Agris

Chemistry Faculty Publications and Presentations

The hypermodified nucleoside N(6)-threonylcarbamoyladenosine (t(6)A37) is present in many distinct tRNA species and has been found in organisms in all domains of life. This post-transcriptional modification enhances translation fidelity by stabilizing the anticodon/codon interaction in the ribosomal decoding site. The biosynthetic pathway of t(6)A37 is complex and not well understood. In bacteria, the following four proteins have been discovered to be both required and sufficient for t(6)A37 modification: TsaC, TsaD, TsaB, and TsaE. Of these, TsaC and TsaD are members of universally conserved protein families. Although TsaC has been shown to catalyze the formation of L-threonylcarbamoyl-AMP, a key intermediate in …


Controlling The Transient Interface Shape And Deposition Profile Left By Desiccation Of Colloidal Droplets On Multiple Polymer Surfaces, Peter David Dunning Aug 2015

Controlling The Transient Interface Shape And Deposition Profile Left By Desiccation Of Colloidal Droplets On Multiple Polymer Surfaces, Peter David Dunning

Theses

A colloidal suspension is a small constituent of insoluble solid particles suspended in a liquid medium. Control over the wetting, evaporation, and deposition patterns left by colloidal suspensions is valuable in many biological, medical, industrial, and agricultural applications. Understanding the governing principles of wetting and evaporative phenomena of these colloidal suspensions may lead to greater control over resultant deposition patterns. Perhaps the most familiar pattern forms when an initially heterogeneous colloidal suspension leaves a dark ring pattern at the edge of a drop. This pattern is referred to as a coffee-stain and it can be seen from dried droplets of …


Towards A Robust Sparse Data Representation In Wireless Sensor Networks, Abu Alsheik Mohammad, Shaowei Lin, Hwee-Pink Tan, Dusit Niyato Aug 2015

Towards A Robust Sparse Data Representation In Wireless Sensor Networks, Abu Alsheik Mohammad, Shaowei Lin, Hwee-Pink Tan, Dusit Niyato

Research Collection School Of Computing and Information Systems

Compressive sensing has been successfully used for optimized operations in wireless sensor networks. However, raw data collected by sensors may be neither originally sparse nor easily transformed into a sparse data representation. This paper addresses the problem of transforming source data collected by sensor nodes into sparse representation with a few nonzero elements. Our contributions that address three major issues include: 1) an effective method that extracts population sparsity of the data, 2) a sparsity ratio guarantee scheme, and 3) a customized leaerning algorithm of the sparsifying dictionary. We introduce an unsupervised neural network to extract an intrinsic sparse coding …


Who Is A Stream? Epistemic Communities, Instrument Constituencies And Advocacy Coalitions In Public Policy-Making, Ishani Mukherjee, Michael Howlett Aug 2015

Who Is A Stream? Epistemic Communities, Instrument Constituencies And Advocacy Coalitions In Public Policy-Making, Ishani Mukherjee, Michael Howlett

Research Collection School of Social Sciences

John Kingdon's Multiple Streams Framework (MSF) was articulated in order to better understand how issues entered onto policy agendas, using the concept of policy actors interacting over the course of sequences of events in what he referred to as the "problem", "policy" and "politics" "streams". However, it is not a priori certain who the agents are in this process and how they interact with each other. As was common at the time, in his study Kingdon used an undifferentiated concept of a ``policy subsystem{''} to group together and capture the activities of various policy actors involved in this process. However, …


Deanotes, College Of Science And Technology, Armstrong State University Aug 2015

Deanotes, College Of Science And Technology, Armstrong State University

College of Science & Technology Dean's Notes (Archived)

No abstract provided.


Evidence For The Persistence Of Food Web Structure After Amphibian Extirpation In A Neotropical Stream, Thomas R. Barnum, John M. Drake, Jose Checo Colón-Gaud, Amanda T. Rugenski, Therese C. Frauendorf, Scott Connelly, Susan S. Kilham, Matt R. Whiles, Karen R. Lips, Catherine M. Pringle Aug 2015

Evidence For The Persistence Of Food Web Structure After Amphibian Extirpation In A Neotropical Stream, Thomas R. Barnum, John M. Drake, Jose Checo Colón-Gaud, Amanda T. Rugenski, Therese C. Frauendorf, Scott Connelly, Susan S. Kilham, Matt R. Whiles, Karen R. Lips, Catherine M. Pringle

Biology: Faculty Publications

Species losses are predicted to simplify food web structure, and disease‐driven amphibian declines in Central America offer an opportunity to test this prediction. Assessment of insect community composition, combined with gut content analyses, was used to generate periphyton–insect food webs for a Panamanian stream, both pre‐ and post‐amphibian decline. We then used network analysis to assess the effects of amphibian declines on food web structure. Although 48% of consumer taxa, including many insect taxa, were lost between pre‐ and post‐amphibian decline sampling dates, connectance declined by less than 3%. We then quantified the resilience of food web structure by calculating …


Male Feminists: Oxymoron Or The Next Step? An Exploration Of Attitudes Associated With Male Feminists, Abigail K. Slowik Aug 2015

Male Feminists: Oxymoron Or The Next Step? An Exploration Of Attitudes Associated With Male Feminists, Abigail K. Slowik

All-Inclusive List of Electronic Theses and Dissertations

Although many studies have examined attitudes toward feminism and feminists, very few have been devoted to the study of attitudes toward male feminists. The existing body of literature has shown mixed results; with feminist men being rated more positively in some regards, and more negative in others. In the current study, Social Identity Theory (Tajfel & Turner, 2004) is used as a framework for understanding factors associated with attitudes towards male feminists, male feminist identification, and gender-self-esteem. Attitudes associated with male feminists were examined in a sample of 466 male and female undergraduate students from Indiana State University. Participants were …


Losartan Treatment Attenuates Tumor-Induced Myocardial Dysfunction, Sarah C.W. Stevens, Markus Velten, Dane J. Youtz, Yvonne Clark, Runfeng Jing, Peter J. Reiser, Sabahattin Bicer, Raymond D. Devine, Donna O. Mccarthy, Loren E. Wold Aug 2015

Losartan Treatment Attenuates Tumor-Induced Myocardial Dysfunction, Sarah C.W. Stevens, Markus Velten, Dane J. Youtz, Yvonne Clark, Runfeng Jing, Peter J. Reiser, Sabahattin Bicer, Raymond D. Devine, Donna O. Mccarthy, Loren E. Wold

College of Nursing Faculty Research and Publications

Fatigue and muscle wasting are common symptoms experienced by cancer patients. Data from animal models demonstrate that angiotensin is involved in tumor-induced muscle wasting, and that tumor growth can independently affect myocardial function, which could contribute to fatigue in cancer patients. In clinical studies, inhibitors of angiotensin converting enzyme (ACE) can prevent the development of chemotherapy-induced cardiovascular dysfunction, suggesting a mechanistic role for the renin–angiotensin–aldosterone system (RAAS). In the present study, we investigated whether an angiotensin (AT) 1-receptor antagonist could prevent the development of tumor-associated myocardial dysfunction. Methods and results: Colon26 adenocarcinoma (c26) cells were implanted into female CD2F1 mice …


Generalization And Maintenance Of High School Teachers' Use Of Behavior Specific Praise Following Direct Behavioral Consultation In Classrooms, Traci Ann Taber Aug 2015

Generalization And Maintenance Of High School Teachers' Use Of Behavior Specific Praise Following Direct Behavioral Consultation In Classrooms, Traci Ann Taber

Dissertations

This study tested the efficacy of in situ direct training on increasing high school teachers’ use of behavior specific praise in the classroom. Of further interest was the extent to which training led to teachers’ maintained praise and generalized praise use in untrained classes. Students’ disruptive behaviors were measured concurrently to test the relationship between increased praise use and decreases in students’ inappropriate behavior in the classroom. Increasing the frequency of teachers’ use of praise statements with students for engaging in appropriate behavior has shown subsequent reduction in the occurrence of classroom disruptions resulting in less time that a teacher …


Coping, Hardiness, And Parental Stress In Parents Of Children Diagnosed With Cancer, Kathryn Lynch Bigalke Aug 2015

Coping, Hardiness, And Parental Stress In Parents Of Children Diagnosed With Cancer, Kathryn Lynch Bigalke

Dissertations

Previous research has demonstrated a significant increase in stress for parents with a child in active cancer treatment. As the number of children diagnosed with cancer continues to rise, there has been a call to identify factors that may contribute to positive outcomes in these families (e.g., Sloper, 2000; Streisand, Kazak, & Tercyak, 2003). Certain effective coping strategies, particularly related to more problem-focused forms of coping and hardiness, appear to be negatively related to parental stress. However, little is known about how these strategies may impact parental stress in families of children in active cancer treatment. The current study assessed …


Assessing Biogeochemical Impacts And Environmental Conditions Associated With Cross-Shelf High Chlorophyll Plumes In The Northern Gulf Of Mexico, Erin Brooke Jones Aug 2015

Assessing Biogeochemical Impacts And Environmental Conditions Associated With Cross-Shelf High Chlorophyll Plumes In The Northern Gulf Of Mexico, Erin Brooke Jones

Dissertations

The northern Gulf of Mexico is a complex marine system subject to episodic physical phenomena such as loop current eddies. Flow fields generated by these eddies can result in cross-shelf exchanges between riverine influenced shelf waters and the offshore water column. This study considers the impacts of high chlorophyll plumes (HCPs) resulting from cross-shelf exchanges to the bio-optical properties of affected waters and how these plumes are influenced by their environment. The seasonal, interannual and decadal chlorophyll cycles of the Gulf of Mexico and the northern Gulf of Mexico are described to provide context for evaluating the ecological effects of …


School Connectedness And Racial-Ethnic Identity Among Alaska Native Students: An Explanatory Sequential Mixed Methods Study, Robert J. Picou Aug 2015

School Connectedness And Racial-Ethnic Identity Among Alaska Native Students: An Explanatory Sequential Mixed Methods Study, Robert J. Picou

Dissertations

This study was conducted from a theoretical foundation of Feagin’s (2010) racial framing and Brayboy’s (2005) tribal critical race theory. The purpose of this study was to examine perceptions of school connectedness as those perceptions relate to racial-ethnic identity among Alaska Native students in a large, predominately White school district. A quantitative phase in which School Climate and Connectedness Survey data were used to evaluate perceptions of school connectedness was followed up by a qualitative phase in which two focus group interviews were conducted to evaluate the degree to which Alaska Native students attributed their perceptions of school connectedness to …


Illinois State, August 2015, Illinois State University, University Marketing And Communications Aug 2015

Illinois State, August 2015, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine


Metabolites As Novel Biomarkers For Childhood Obesity-Related Traits In Mexican-American Children, V. S. Farook, L. Reddivari, G. Chittoor, S. Puppala, Rector Arya, S. P. Fowler, Joanne E. Curran, John Blangero, Ravi Duggirala Aug 2015

Metabolites As Novel Biomarkers For Childhood Obesity-Related Traits In Mexican-American Children, V. S. Farook, L. Reddivari, G. Chittoor, S. Puppala, Rector Arya, S. P. Fowler, Joanne E. Curran, John Blangero, Ravi Duggirala

School of Medicine Publications

Background/Objectives Although newer approaches have identified several metabolites associated with obesity, there is paucity of such information in paediatric populations, especially among Mexican-Americans (MAs) who are at high risk of obesity. Therefore, we performed a global serum metabolite screening in MA children to identify biomarkers of childhood obesity. Methods We selected 15 normal-weight, 13 overweight and 14 obese MA children (6-17 years) and performed global serum metabolite screening using ultra-performance liquid chromatography/quadruple orthogonal acceleration time of flight tandem micro mass spectrometer. Metabolite values were analysed to assess mean differences among groups using one-way analysis of variance, to test for linear …


Spider Mites In Corn, Alice Ruckert, Ricardo Ramirez, Clark Israelsen Aug 2015

Spider Mites In Corn, Alice Ruckert, Ricardo Ramirez, Clark Israelsen

All Current Publications

This fact sheet provides information about Banks grass mites and two-spotted spider mites, important agricultural pests of corn and a wide variety of other crop, garden, and landscape plants. It includes how to identify them, their life cycle, crop injury, and management strategies.


Visible-Light Activation Of Tio2 Photocatalysts: Advances In Theory And Experiments, Vinodkumar Etacheri, Cristiana Di Valentin, Jenny Schneider, Detlef Bahnemann, Suresh Pillai Aug 2015

Visible-Light Activation Of Tio2 Photocatalysts: Advances In Theory And Experiments, Vinodkumar Etacheri, Cristiana Di Valentin, Jenny Schneider, Detlef Bahnemann, Suresh Pillai

Articles

The remarkable achievement by Fujishima and Honda (1972) in the photo-electrochemical water splitting results in the extensive use of TiO2 nanomaterials for environmental purification and energy storage/conversion applications. Though there are many advantages for the TiO2 compared to other semiconductor photocatalysts, its band gap of 3.2 eV restrains application to the UV-region of the electromagnetic spectrum ≤387.5 nm. As a result, development of visible-light active titanium dioxide is one of the key challenges in the field of semiconductor photocatalysis. In this review, advances in the strategies for the visible light activation, origin of visible-light activity, and electronic structure of various …


Hands-On Precision Agriculture Data Management Workshops For Producers And Industry Professionals: Development And Assessment, Joe D. Luck, John P. Fulton, Jennifer Rees Aug 2015

Hands-On Precision Agriculture Data Management Workshops For Producers And Industry Professionals: Development And Assessment, Joe D. Luck, John P. Fulton, Jennifer Rees

Journal of Extension

Three Precision Agriculture Data Management workshops regarding yield monitor data were conducted in 2014, reaching 62 participants. Post-workshop surveys (n=58) indicated 73% of respondents experienced a moderate to significant increase in knowledge related to yield monitor data usage. Another 72% reported that they planned to utilize best management practices presented or would expand their current practices based on knowledge gained. One-year post-workshop survey (n=14) results indicated that far less (36%) were able to implement some of the techniques presented. However, comments indicated that accessible follow-up material would be beneficial in successfully integrating learning topics into data management systems.


Fatty Acids Linked To Cardiovascular Mortality Are Associated With Risk Factors, Sven O. E. Ebbesson, V. Saroja Voruganti, Paul B. Higgins, Richard R. Fabsitz, Lars O. Ebbesson, Sandra Laston, William S. Harris, John Kennish, Benjamin D. Umans, Hong Wang Aug 2015

Fatty Acids Linked To Cardiovascular Mortality Are Associated With Risk Factors, Sven O. E. Ebbesson, V. Saroja Voruganti, Paul B. Higgins, Richard R. Fabsitz, Lars O. Ebbesson, Sandra Laston, William S. Harris, John Kennish, Benjamin D. Umans, Hong Wang

School of Medicine Publications

Background. Although saturated fatty acids (FAs) have been linked to cardiovascular mortality, it is not clear whether this outcome is attributable solely to their effects on low-density lipoprotein cholesterol (LDL-C) or whether other risk factors are also associated with FAs. The Western Alaskan Native population, with its rapidly changing lifestyles, shift in diet from unsaturated to saturated fatty acids and dramatic increase in cardiovascular disease (CVD), presents an opportunity to elucidate any associations between specific FAs and known CVD risk factors.

Objective. We tested the hypothesis that the specific FAs previously identified as related to CVD mortality are also associated …


Bioactive Glass Reinforced Elastomer Composites For Skeletal Regeneration: A Review, Ehsan Zeimaran, Sara Pourshahrestani, Ivan Djordjevic, Belinda Pingguan-Murphy, Nahrizul Adib Kadri, Mark R. Towler Aug 2015

Bioactive Glass Reinforced Elastomer Composites For Skeletal Regeneration: A Review, Ehsan Zeimaran, Sara Pourshahrestani, Ivan Djordjevic, Belinda Pingguan-Murphy, Nahrizul Adib Kadri, Mark R. Towler

Chemical and Biochemical Engineering Faculty Research & Creative Works

Biodegradable elastomers have clinical applicability due to their biocompatibility, tunable degradation and elasticity. The addition of bioactive glasses to these elastomers can impart mechanical properties sufficient for hard tissue replacement. Hence, a composite with a biodegradable polymer matrix and a bio glass filler can offer a method of augmenting existing tissue. This article reviews the applications of such composites for skeletal augmentation.


Accumulation Of Gas-Phase Methamphetamine On Clothing, Toy Fabrics, And Skin Oil, G. Morrison, N. V. Shakila, K. Parker Aug 2015

Accumulation Of Gas-Phase Methamphetamine On Clothing, Toy Fabrics, And Skin Oil, G. Morrison, N. V. Shakila, K. Parker

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

To better understand methamphetamine exposure and risk for occupants of former residential clandestine methamphetamine laboratories, we measured the dynamic accumulation of methamphetamine in skin oil, cotton and polyester (PE) clothing, upholstery, and toy fabric (substrates) exposed to 15-30 ppb (91-183 μg/m3) neutral methamphetamine in air for up to 60 days. The average equilibrium partition coefficients at 30% RH, in units of μg of methamphetamine per gram of substrate per ppb, are 3.0 ± 0.2 for a PE baby blanket, 5.6 ± 3.5 for a PE fabric toy, 3.7 ± 0.2 for a PE shirt, 18.3 ± 8.0 for a PE/cotton …


Vibrational Energy Levels Of The Simplest Criegee Intermediate (Ch₂Oo) From Full-Dimensional Lanczos, Mctdh, And Multimode Calculations, Hua-Gen Yu, Steve Alexandre Ndengué, Jun Li, Richard Dawes, Hua Guo Aug 2015

Vibrational Energy Levels Of The Simplest Criegee Intermediate (Ch₂Oo) From Full-Dimensional Lanczos, Mctdh, And Multimode Calculations, Hua-Gen Yu, Steve Alexandre Ndengué, Jun Li, Richard Dawes, Hua Guo

Chemistry Faculty Research & Creative Works

Accurate vibrational energy levels of the simplest Criegee intermediate (CH2OO) were determined on a recently developed ab initio based nine-dimensional potential energy surface using three quantum mechanical methods. the first is the iterative Lanczos method using a conventional basis expansion with an exact Hamiltonian. the second and more efficient method is the multi-configurational time-dependent Hartree (MCTDH) method in which the potential energy surface is refit to conform to the sums-of-products requirement of MCTDH. Finally, the energy levels were computed with a vibrational self-consistent field/virtual configuration interaction method in MULTIMODE. the low-lying levels obtained from the three methods are …


Terrorist And Insurgent Unmanned Aerial Vehicles: Use, Potentials, And Military Implications, Robert J. Bunker Dr. Aug 2015

Terrorist And Insurgent Unmanned Aerial Vehicles: Use, Potentials, And Military Implications, Robert J. Bunker Dr.

Books, Monographs & Collaborative Studies

This manuscript focuses on the present threat posed by terrorist and insurgent use of unmanned aerial vehicles (UAVs) as well as associated future threat potentials. This work presents a counterintuitive analysis in the sense that armed drones are typically viewed as a component of America’s conventional warfighting prowess—not a technology that would be used against U.S. troops deployed overseas or against civilians back home. The emerging threat of such UAV use against the United States is investigated, and the unique analysis and creative approach related to the threat scenario variants generated are very informative. Hopefully, the larger implications posed by …


Adiporon, The First Orally Active Adiponectin Receptor Activator, Attenuates Postischemic Myocardial Apoptosis Through Both Ampk-Mediated And Ampk-Independent Signalings., Yanqing Zhang, Jianli Zhao, Rui Li, Wayne Bond Lau, Yue-Xing Yuan, Bin Liang, Rong Li, Er-He Gao, Walter J. Koch, Xin-Liang Ma, Ya-Jing Wang Aug 2015

Adiporon, The First Orally Active Adiponectin Receptor Activator, Attenuates Postischemic Myocardial Apoptosis Through Both Ampk-Mediated And Ampk-Independent Signalings., Yanqing Zhang, Jianli Zhao, Rui Li, Wayne Bond Lau, Yue-Xing Yuan, Bin Liang, Rong Li, Er-He Gao, Walter J. Koch, Xin-Liang Ma, Ya-Jing Wang

Department of Emergency Medicine Faculty Papers

Adiponectin (APN) is a cardioprotective molecule. Its reduction in diabetes exacerbates myocardial ischemia/reperfusion (MI/R) injury. Although APN administration in animals attenuates MI/R injury, multiple factors limit its clinical application. The current study investigated whether AdipoRon, the first orally active molecule that binds APN receptors, may protect the heart against MI/R injury, and if so, to delineate the involved mechanisms. Wild-type (WT), APN knockout (APN-KO), and cardiomyocyte specific-AMPK dominant negative (AMPK-DN) mice were treated with vehicle or AdipoRon (50 mg/kg, 10 min prior to MI) and subjected to MI/R (30 min/3-24 h). Compared with vehicle, oral administration of AdipoRon to WT …


The Rise And Fall Of Poly(Adp-Ribose): An Enzymatic Perspective., John M. Pascal, Tom Ellenberger Aug 2015

The Rise And Fall Of Poly(Adp-Ribose): An Enzymatic Perspective., John M. Pascal, Tom Ellenberger

Department of Biochemistry and Molecular Biology Faculty Papers

Human cells respond to DNA damage with an acute and transient burst in production of poly(ADP-ribose), a posttranslational modification that expedites damage repair and plays a pivotal role in cell fate decisions. Poly(ADP-ribose) polymerases (PARPs) and glycohydrolase (PARG) are the key set of enzymes that orchestrate the rise and fall in cellular levels of poly(ADP-ribose). In this perspective, we focus on recent structural and mechanistic insights into the enzymes involved in poly(ADP-ribose) production and turnover, and we highlight important questions that remain to be answered.