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Finding A Balance In An Unbalanced System: Analysis Of The United State Immigration Laws, Joshua Wayne Higdon

Morehead State Theses and Dissertations

A Thesis Presented to the Faculty of the College of Caudill College of Arts, Humanities and Social Sciences Morehead State University in Partial Fulfillment of the Requirements for the Degree Master of Arts by Joshua Wayne Higdon August 3, 2015.

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Role Of Fanca In Dna Damage Repair, Anaid Benitez

Open Access Dissertations

Fanconi anemia (FA) is a severe genetic disorder characterized by bone marrow failure, developmental defects, chromosomal instability, and predisposition to cancer. FA cells are hypersensitive to DNA crosslinking compounds including mitomycin C (MMC), cisplatin, and diepoxybutane, which make defective interstrand crosslink (ICL) repair mechanisms a hallmark for the disease. Of the 17 genes associated with FA, mutations in the complementation group A (FANCA) account for ~64% of all patient cases. Studies explored in this dissertation comprise the biochemical details for the functional role of FANCA in DNA ICL repair and the first biochemical evidence for its possible role in double-strand …

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Farming In The Commons, Fishing In The Congress, And U.S. Aquaculture In The 21st Century, Aaron Welch

Open Access Dissertations

Fisheries and aquaculture policy in the United States exhibits a peculiar duality. Commercial fishing is functionally open-access, heavily subsidized, and regulated by a federal bureaucracy staffed in part by fishing industry representatives. Marine aquaculture, in contrast, is effectively forbidden. Today there are no functioning fish farms anywhere in the federal waters of the United States, largely due to a regulatory environment that discourages applications for aquaculture permits. This bifurcated policy does not seem to be dependent on any specific environmental or economic rationale. Instead, this policy appears to be the product of a series of individual assumptions and policy choices …

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Gsu View, 2015-08-03, Office Of Marketing And Communications

GSU View

Newsletter published by Governors State University 2007-current.

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Korean Migrant Youth Identity Work In The Transnational Social Field: A Link Between Identity, Transnationalism, And New Media Literacy, Sujin Kim

Dissertations

Informed by the new understandings of space, culture, and identity in the fast-changing world where communication technology connects and compresses multiple spaces, this qualitative study examines how Korean migrant youth understand, negotiate, and articulate their complex identities across and beyond various borders. The research questions were: (1) What are the contexts in which migrant youth negotiate their identities? (2) How do youth understand and negotiate their sense of belonging? (3) How do youth’s cultural and literacy practices, particularly in new media, inform and shape their identities? Using an ethnographic case study design, I collected data from 32 survey participants and …

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A Novel Toxin - And The First Ever Found - For A Deadly Pathogen, M. Tuberculosis, Jeff Hansen

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No abstract provided.

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Truncating Mutation In The Autophagy Gene Uvrag Confers Oncogenic Properties And Chemosensitivity In Colorectal Cancers, Shanshan He, Zhen Zhao, Yongfei Yang, Douglas O'Connell, Xiaowei Zhang, Soohwan Oh, Binyun Ma, Joo-Hyung Lee, Tian Zhang, Bino Varghese, Janae Yip, Sara Dolatshahi Pirooz, Ming Li, Yong Zhang, Guo-Min Li, Sue Ellen Martin, Keigo Machida, Chengyu Liang

Toxicology and Cancer Biology Faculty Publications

Autophagy-related factors are implicated in metabolic adaptation and cancer metastasis. However, the role of autophagy factors in cancer progression and their effect in treatment response remain largely elusive. Recent studies have shown that UVRAG, a key autophagic tumour suppressor, is mutated in common human cancers. Here we demonstrate that the cancer-related UVRAG frameshift (FS), which does not result in a null mutation, is expressed as a truncated UVRAG^FS in colorectal cancer (CRC) with microsatellite instability (MSI), and promotes tumorigenesis. UVRAG^FS abrogates the normal functions of UVRAG, including autophagy, in a dominant-negative manner. Furthermore, expression of UVRAG^FS can …

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A Novel Toxin - And The First Ever Found - For A Deadly Pathogen, M. Tuberculosis, Jeff Hansen

Browse All News

No abstract provided.

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Mythcon 46 - The Arthurian Mythos, The Mythopoeic Society

Mythcon Programs

Mythcon 46 will be held at the Hotel Elegante Event and Conference Center in Colorado Springs, Colorado. The Hotel Elegante features a full restaurant, a sports bar, and a casual bakery/ coffee shop for drinks and snacks. The entire hotel is non-smoking.

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Tailored Delivery Of Analgesic Ziconotide Across A Blood Brain Barrier Model Using Viral Nanocontainers, Prachi Anand, Alison O’Neil, Emily Lin, Trevor Douglas, Mandë Holford

Publications and Research

The blood brain barrier (BBB) is often an insurmountable obstacle for a large number of candidate drugs, including peptides, antibiotics, and chemotherapeutic agents. Devising an adroit delivery method to cross the BBB is essential to unlocking widespread application of peptide therapeutics. Presented here is an engineered nanocontainer for delivering peptidic drugs across the BBB encapsulating the analgesic marine snail peptide ziconotide (Prialt®). We developed a bi-functional viral nanocontainer based on the Salmonella typhimurium bacteriophage P22 capsid, genetically incorporating ziconotide in the interior cavity, and chemically attaching cell penetrating HIV-Tat peptide on the exterior of the capsid. Virus like particles (VLPs) …

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Predicting Landscape-Scale Co 2 Flux At A Pasture And Rice Paddy With Long-Term Hyperspectral Canopy Reflectance Measurements, J. H. Matthes, S. H. Knox, C. Sturtevant, O. Sonnentag

Dartmouth Scholarship

Measurements of hyperspectral canopy reflectance provide a detailed snapshot of information regarding canopy biochemistry, structure and physiology. In this study, we collected 5 years of repeated canopy hyperspectral reflectance measurements for a total of over 100 site visits within the flux footprints of two eddy covariance towers at a pasture and rice paddy in northern California. The vegetation at both sites exhibited dynamic phenology, with significant interannual variability in the timing of seasonal patterns that propagated into interannual variability in measured hyperspectral reflectance. We used partial least-squares regression (PLSR) modeling to leverage the information contained within the entire canopy reflectance …

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Aviation Bird Hazard In Nexrad Dual Polarization Weather Radar Confirmed By Visual Observations, Bradley M. Muller, Frederick R. Mosher, Christopher G. Herbster, Anthony T. Brickhouse

International Journal of Aviation, Aeronautics, and Aerospace

Birds represent a significant hazard to flying aircraft as illustrated by the “Miracle on the Hudson” encounter in 2009 between U.S. Airways Flight 1549 and a flock of Canada Geese, forcing the flight to ditch in the river. Birds are common in the skies over Florida during the spring migration season, and often appear in the National Weather Service’s (NWS) NEXRAD weather radar imagery as an easily recognizable signature known as a “roost ring.” This paper presents a NEXRAD roost ring case in central Florida in a rare instance where the signatures were confirmed by visual observations of the birds. …

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Artificial Superintelligence: Extinction Or Nirvana?, Jens Pohl

Architecture

The purpose of this paper is to explore the subject of Artificial General Intelligence (AGI) and Artificial Superintelligence (ASI) and identify in summary form the principal drivers and current status of Artificial Narrow Intelligence (ANI), the impact that intelligent software in combination with the Internet serving as a Global Knowledgebase is already having on human capabilities, the likely path to ASI, the possible threats posed by ASI and proposed measures to curtail those threats, and finally the potential benefits to the human species if AGI and ASI remain under human control.

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Winter Deicing Effects On Groundwater Quality Beneath Permeable Asphalt, Derek R. Angel

Master's Theses

This study examined the effects of winter deicing on groundwater quality beneath an 860-m² permeable asphalt parking lot at the University of Connecticut in Storrs, Connecticut. While the beneficial impacts of permeable asphalt on water quality and hydrology have been documented in the literature and include increases in groundwater recharge, reduced peak flows and reductions in metals and hydrocarbon contaminant concentrations in groundwater, chloride has not been observed to be filtered from percolate beneath permeable asphalt. The potential issues related to chloride contamination of groundwater include aquatic toxicity and heavy metals mobilization. Monitoring wells were installed up-gradient and down-gradient …

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Sound Production And Associated Behavior Of Tagged Fin Whales (Balaenoptera Physalus) In The Southern California Bight, Alison K. Stimpert, Stacy L. Deruiter, Erin A. Falcone, John Joseph

University Faculty Publications and Creative Works

For marine animals, acoustic communication is critical for many life functions, yet individual calling behavior is poorly understood for most large whale species. These topics are important for understanding whale social behavior and can also serve as a baseline for behavioral studies assessing whale response to disturbance. Using a new technique for identifying the calling individual, we measured body orientation, dive behavior, and surface social behavior in relation to call production for tagged fin whales in Southern California. Results: Behavioral metrics associated with elevated call rates included shallow maximum dive depths (10-15m), little body movement, negative pitch in body orientation, …

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Impact Of Standardized Oral Health Assessment On Preventing Ventilator-Associated Events, Juana Ambriz De Williams

Evidence-Based Practice Project Reports

Ventilator-associated pneumonia (VAP) is a common but preventable health-care associated infection that affects up to 20% of mechanically ventilated adult patients, resulting in estimated mortality rates ranging from 13% to 55% (Chahoud, Semaan, Almoosa, 2015; Melsen et al., 2013). In an effort to reduce morbidity, mortality and related costs, the Centers for Disease Control and Prevention (CDC) and the National Healthcare Safety Network (NHSN), proposed ventilator-associated pneumonia prevention as a national patient safety goal. In 2014, amid growing concerns that the subjectivity of existing definitions had led to inconsistent reporting, thereby impeding efforts to reduce VAP, the CDC refocused surveillance …

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Hydrologic Modeling Of The Effects Of Stormwater Runoff In Plaster Creek Watershed, Ryan Degroot, Julie Wildschut, Robert Hoeksema

Student Papers and Reports

No abstract provided.

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Mother-Daughter Sexual Communication And Adolescent Sexual Risk Behaviors: Investigating Racial/Ethnic Differences And Family Factors, Viana Turcios-Cotto

Doctoral Dissertations

Sexually transmitted infections and adolescent childbearing disproportionately affect adolescents of color. Research suggests these negative health outcomes may be due in part to potential cultural differences in how families approach adolescent sexual behavior. Using a diverse urban sample of 13- to 17-year-old girls (N=194), this study explored potentially important aspects of mother-adolescent sexual communication by asking: 1) How does mother-daughter sexual communication (i.e., frequency, tone, embarrassment) relate to adolescent sexual risk when communication is considered dyadically? 2) What are the racial/ethnic differences, if any, in mother-daughter sexual communication and concordance in reports of communication? Is the relation between communication and …

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Influence Of Maternal Childhood Adversity On The Psycho-Neuroendocrine-Inflammatory Profile During Pregnancy, Karen J. Kotz, Herbert L. Mathews, Linda Witek Janusek

Sigma Foundation for Nursing Research Grant Reports

The purpose of this study was to investigate the relationship among maternal childhood adversity, psychological, and neuroendocrine-immune processes during pregnancy; and to explore the impact of maternal stress on neonatal outcomes (birthweight and gestational age). In addition, the modifying effect of maternal social support was examined.

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3d Block-Based Restoration (Bbr) Method Addressing Space-Variance In Fluorescence Microscopy Due To Thick Samples With Non-Uniform Refractive Index, Sreya Ghosh

Electronic Theses and Dissertations Archive

This dissertation proposes a method to restore 3D fluorescence microscopy images obtained from samples with non-uniform refractive index (RI). Existing restoration methods assume the sample is thin and/or has uniform RI in order to keep the computations practical. This is an invalid assumption for most biological samples, which are optically thick because they are neither thin (>5 µm) nor have uniform RI. Specimen properties introduce spherical aberration (SA) in the gathered 3D image, which is dependent on the RI variability between the specimen and the imaging lens’s immersion medium as well as the thickness of the sample. Understanding the …

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Diversity Of Synechococcus At The Martha's Vineyard Coastal Observatory: Insights From Culture Isolations, Clone Libraries, And Flow Cytometry, Kristen R. Hunter-Cevera, Anton F. Post, Emily E. Peacock, Heidi M. Sosik

Graduate School of Oceanography Faculty Publications

The cyanobacterium Synechococcus is a ubiquitous, important phytoplankter across the world’s oceans. A high degree of genetic diversity exists within the marine group, which likely contributes to its global success. Over 20 clades with different distribution patterns have been identified. However, we do not fully understand the environmental factors that control clade distributions. These factors are likely to change seasonally, especially in dynamic coastal systems. To investigate how coastal Synechococcus assemblages change temporally, we assessed the diversity of Synechococcus at the Martha’s Vineyard Coastal Observatory (MVCO) over three annual cycles with culture-dependent and independent approaches. We further investigated the abundance …

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Installation Of Rain Gardens In The Alger Heights Community, Wesley Dykstra, Dena De Kryger, Mike Ryskamp, David P. Warners

Student Papers and Reports

No abstract provided.

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Scope And Mechanistic Analysis For Chemoselective Hydrogenolysis Of Carbonyl Compounds Catalyzed By A Cationic Ruthenium Hydride Complex With A Tunable Phenol Ligand, Nishantha Kumara Kalutharage, Chae S. Yi

Chemistry Faculty Research and Publications

A cationic ruthenium hydride complex, [(C₆H₆)(PCy₃)(CO)RuH]⁺BF₄^– (1), with a phenol ligand was found to exhibit high catalytic activity for the hydrogenolysis of carbonyl compounds to yield the corresponding aliphatic products. The catalytic method showed exceptionally high chemoselectivity toward the carbonyl reduction over alkene hydrogenation. Kinetic and spectroscopic studies revealed a strong electronic influence of the phenol ligand on the catalyst activity. The Hammett plot of the hydrogenolysis of 4-methoxyacetophenone displayed two opposite linear slopes for the catalytic system 1/p-X-C₆H₄OH (ρ = …

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Guiding Principles For Management Of Forested, Agricultural, And Urban Watersheds, Pamela J. Edwards, Jon E. Schoonover, Karl W.J Williard

Journal of Contemporary Water Research and Education

Human actions must be well planned and include consideration of their potential influences on water and aquatic ecosystems "“ such consideration is the foundation of watershed management. Watersheds are the ideal land unit for managing and protecting water resources and aquatic health because watersheds integrate the physical, biological and chemical processes within their boundaries. Managed forested watersheds tend to have more natural watershed functions and better water quality than other land uses. Land uses with greater amounts of soil disturbance and permanent reductions in infiltration, such as in agricultural or urban/developed settings, usually have greater undesirable hydrologic alterations and poorer …

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Chemical Mixture Methodology (Cmm): Using 15 Health Code Numbers, Kolyne S. De Jesus, Juan Yao, Clifford Glantz, Xiao-Ying Yu

STAR Program Research Presentations

The Chemical Mixture Methodology (CMM) is used for an emergency response and safety planning for chemical mixtures that cause irreversible or serious health effects. There are three major components of the CMM: Health Code Numbers (HCNs), the Hazard Index, and the Protective Action Criteria values. The HCNs are akin to medical diagnostic codes; they categorize the adverse health outcome that could be induced by exposure to an individual hazardous chemical. Currently, 60 HCNs are used in the CMM to characterize potential health effects for over 3,000 chemicals. Chemicals may have one or more HCNs; however, a maximum of 10 HCNs …

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The Effect Of Environmental Selection Pressure On The Rate Of Recombination To An Advantageous Receptor Mutation In Bovine Coronavirus, Gavin Schroter, Sally Hall, Mona Hwang, Monica Borucki

STAR Program Research Presentations

Bovine Coronavirus (BCoV) is an important analogue in understanding the effectiveness of zoonotic, single-stranded, positive sense RNA viruses. Many of the most recent viral outbreaks have been attributed to RNA viruses that have one, or more, animal reservoirs [1]. BCoV is such a great candidate for studying these types of viruses because they are from the family Coronaviridae, which also contains the viruses that cause severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). The goal of this study was to observe changes in genetic makeup of the virus’ outer membrane Spike protein via recombination between two …

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Design And Fabrication Of Liquid Scintillator Counter, Andrea Calderon Saucedo, John L. Orrell

STAR Program Research Presentations

Pacific Northwest National Laboratory (PNNL) is currently developing an ultra-low background liquid scintillator counter (ULB LSC) in the shallow underground laboratory. At a depth of 35-meters water-equivalent, the underground laboratory has a multi-layered shielding to keep out cosmic-ray induced background. The ULB LSC, which is located in a clean room facility, is a multi-layered design made up of various materials, including plastic scintillator veto panels, borated polyethylene, lead and copper. These layers help lower the contributions of the terrestrial background and intrinsic background, resulting from the impurities present in the materials, to the overall background count rate observed by the …

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Sediment Loss Of Santa Rosa Island Slopes: An Erosional Study, Michael Perez

STAR Program Research Presentations

Ranching began on Santa Rosa Island in the 1840’s, consequently introducing nonnative megafauna that put novel selective grazing pressures on endemic plant species. Their movement patterns also altered sediment integrity as the land was denuded of any stabilizing vegetation. Dense groves of island oak (Q. tomentella) are known to aid in sediment deposition and retention. The groves also function to collect water during periods of intense fog that are common to the island. This experiment sought to quantify the volume of sediment that has been lost on a south facing slope in the middle of the island that …

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Chemical Oxygen Demand Reduction Using The Algae Dunaliella Primolecta And Chlorella Vulgaris, Angeles L. Mora, Alejandro Hernandez, Alejandro Calderón-Urrea

STAR Program Research Presentations

Farm industry wastewater is characterized by high organic materials and by high chemical oxygen demand (COD). Farms with large livestock and poultry operations can be a major source of wastewater thus a major concern for effective environmental and industrial management. Effective environmental and industrial management are high in cost therefor biofuels produced from plants have a potential of replacing a portion of fossil fuel consumption with a renewable efficient alternative. Due to California’s water crisis in the recent years, it is questioned if a biological treatment system that uses algal growth to create renewable energy in the form of biodiesel …

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Fatty Acid Recovery And Identification In Mars Analogue Soil Samples, Kimberly E. Lykens

STAR Program Research Presentations

A primary goal of NASA’s Mars 2020 mission is to gather and store samples of Mars soil that could possibly be returned to Earth in a future mission for investigations into past or present life. In years leading up to a potential sample return mission on Mars and potentially other worlds, samples taken from Chile’s Atacama Desert, the most arid, biologically limited desert in the world, are valuable in developing a capacity for biosignature detection, specifically when exploring fatty acid abundance. Eighteen samples were collected from two sites in the Atacama characterized by biological soil crusts (BSC). BSCs are areas …

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Full-Text Articles in Entire DC Network

Finding A Balance In An Unbalanced System: Analysis Of The United State Immigration Laws, Joshua Wayne Higdon

Morehead State Theses and Dissertations

Role Of Fanca In Dna Damage Repair, Anaid Benitez

Open Access Dissertations

Farming In The Commons, Fishing In The Congress, And U.S. Aquaculture In The 21st Century, Aaron Welch

Open Access Dissertations

Gsu View, 2015-08-03, Office Of Marketing And Communications

GSU View

Korean Migrant Youth Identity Work In The Transnational Social Field: A Link Between Identity, Transnationalism, And New Media Literacy, Sujin Kim

Dissertations

A Novel Toxin - And The First Ever Found - For A Deadly Pathogen, M. Tuberculosis, Jeff Hansen

Browse All News

Toxicology and Cancer Biology Faculty Publications

A Novel Toxin - And The First Ever Found - For A Deadly Pathogen, M. Tuberculosis, Jeff Hansen

Browse All News

Mythcon 46 - The Arthurian Mythos, The Mythopoeic Society

Mythcon Programs

Tailored Delivery Of Analgesic Ziconotide Across A Blood Brain Barrier Model Using Viral Nanocontainers, Prachi Anand, Alison O’Neil, Emily Lin, Trevor Douglas, Mandë Holford

Publications and Research

Predicting Landscape-Scale Co 2 Flux At A Pasture And Rice Paddy With Long-Term Hyperspectral Canopy Reflectance Measurements, J. H. Matthes, S. H. Knox, C. Sturtevant, O. Sonnentag

Dartmouth Scholarship

Aviation Bird Hazard In Nexrad Dual Polarization Weather Radar Confirmed By Visual Observations, Bradley M. Muller, Frederick R. Mosher, Christopher G. Herbster, Anthony T. Brickhouse

International Journal of Aviation, Aeronautics, and Aerospace

Artificial Superintelligence: Extinction Or Nirvana?, Jens Pohl

Architecture

Winter Deicing Effects On Groundwater Quality Beneath Permeable Asphalt, Derek R. Angel

Master's Theses

Sound Production And Associated Behavior Of Tagged Fin Whales (Balaenoptera Physalus) In The Southern California Bight, Alison K. Stimpert, Stacy L. Deruiter, Erin A. Falcone, John Joseph

University Faculty Publications and Creative Works

Impact Of Standardized Oral Health Assessment On Preventing Ventilator-Associated Events, Juana Ambriz De Williams

Evidence-Based Practice Project Reports

Hydrologic Modeling Of The Effects Of Stormwater Runoff In Plaster Creek Watershed, Ryan Degroot, Julie Wildschut, Robert Hoeksema

Student Papers and Reports

Mother-Daughter Sexual Communication And Adolescent Sexual Risk Behaviors: Investigating Racial/Ethnic Differences And Family Factors, Viana Turcios-Cotto

Doctoral Dissertations

Influence Of Maternal Childhood Adversity On The Psycho-Neuroendocrine-Inflammatory Profile During Pregnancy, Karen J. Kotz, Herbert L. Mathews, Linda Witek Janusek

Sigma Foundation for Nursing Research Grant Reports

3d Block-Based Restoration (Bbr) Method Addressing Space-Variance In Fluorescence Microscopy Due To Thick Samples With Non-Uniform Refractive Index, Sreya Ghosh

Electronic Theses and Dissertations Archive

Diversity Of Synechococcus At The Martha's Vineyard Coastal Observatory: Insights From Culture Isolations, Clone Libraries, And Flow Cytometry, Kristen R. Hunter-Cevera, Anton F. Post, Emily E. Peacock, Heidi M. Sosik

Graduate School of Oceanography Faculty Publications

Installation Of Rain Gardens In The Alger Heights Community, Wesley Dykstra, Dena De Kryger, Mike Ryskamp, David P. Warners

Student Papers and Reports

Scope And Mechanistic Analysis For Chemoselective Hydrogenolysis Of Carbonyl Compounds Catalyzed By A Cationic Ruthenium Hydride Complex With A Tunable Phenol Ligand, Nishantha Kumara Kalutharage, Chae S. Yi

Chemistry Faculty Research and Publications

Guiding Principles For Management Of Forested, Agricultural, And Urban Watersheds, Pamela J. Edwards, Jon E. Schoonover, Karl W.J Williard

Journal of Contemporary Water Research and Education

Chemical Mixture Methodology (Cmm): Using 15 Health Code Numbers, Kolyne S. De Jesus, Juan Yao, Clifford Glantz, Xiao-Ying Yu

STAR Program Research Presentations

The Effect Of Environmental Selection Pressure On The Rate Of Recombination To An Advantageous Receptor Mutation In Bovine Coronavirus, Gavin Schroter, Sally Hall, Mona Hwang, Monica Borucki

STAR Program Research Presentations

Design And Fabrication Of Liquid Scintillator Counter, Andrea Calderon Saucedo, John L. Orrell

STAR Program Research Presentations

Sediment Loss Of Santa Rosa Island Slopes: An Erosional Study, Michael Perez

STAR Program Research Presentations

Chemical Oxygen Demand Reduction Using The Algae Dunaliella Primolecta And Chlorella Vulgaris, Angeles L. Mora, Alejandro Hernandez, Alejandro Calderón-Urrea

STAR Program Research Presentations

Fatty Acid Recovery And Identification In Mars Analogue Soil Samples, Kimberly E. Lykens

STAR Program Research Presentations