Digital Commons Network^™

Coastal Sediment Elevation Change Following Anthropogenic Mangrove Clearing, Heather Lyn Hayden, Elise F. Granek

Environmental Science and Management Faculty Publications and Presentations

Coastal mangrove forests along tropical shorelines serve as an important interface between land and sea. They provide a physical buffer protecting the coastline from erosion and act as sediment “traps” catching terrestrial sediment, thus preventing smothering of subtidal coral reefs. Coastal development that removes mangrove habitat may impact adjacent nearshore coral reefs through sedimentation and nutrient loading. We examined differences in sediment elevation change between patches of open-coast intact and anthropogenically cleared red mangroves (Rhizophora mangle) on the east side of Turneffe Atoll, Belize, to quantify changes following mangrove clearing. Samples were collected over a 24 month period at five …

Ecomedia: Key Issues, Stephen Rust, Salma Monani, Sean Cubitt

Gettysburg College Faculty Books

Ecomedia: Key Issues is a comprehensive textbook introducing the burgeoning field of ecomedia studies to provide an overview of the interface between environmental issues and the media globally. Linking the world of media production, distribution, and consumption to environmental understandings, the book addresses ecological meanings encoded in media texts, the environmental impacts of media production, and the relationships between media and cultural perceptions of the environment. [From the publisher]

Wall Mechanical Properties And Hemodynamics Of Unruptured Intracranial Aneurysms, J. R. Cebral, X. Duan, Bong Jae Chung, C. Putman, Khaled Aziz, A. M. Robertson

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

BACKGROUND AND PURPOSE: Aneurysm progression and rupture is thought to be governed by progressive degradation and weakening of the wall in response to abnormal hemodynamics. Our goal was to investigate the relationship between the intra-aneurysmal hemodynamic conditions and wall mechanical properties in human aneurysms. MATERIALS AND METHODS: A total of 8 unruptured aneurysms were analyzed. Computational fluid dynamics models were constructed from preoperative 3D rotational angiography images. The aneurysms were clipped, and the domes were resected and mechanically tested to failure with a uniaxial testing system under multiphoton microscopy. Linear regression analysis was performed to explore possible correlations between hemodynamic …

Method And System For Diagnosis Of Lawsonia Intracellularis, Harold F. Stills Jr., David W. Horohov, Allen E. Page

Microbiology, Immunology and Molecular Genetics Faculty Patents

A method, system, and kit are provided for diagnosing L. intracellularis infection or exposure in a subject. The method includes purifying whole L. intracellularis from host cells and host debris produced in or on a suitable medium and adhering the purified whole L. intracellularis on a suitable material to form an antigen substrate for determining whether a subject produces L. intracellularis-specific antibodies against the antigen to thereby indicate L. intracellularis exposure or infection in the subject. The kit includes purified whole L. intracellularis produced from host cells and host debris adhered to a suitable material to form an antigen …

Host Switching Vs. Host Sharing In Overlapping Sylvatic Trypanosoma Cruzi Transmission Cycles, Christopher Kribs, Christopher Mitchell

Mathematics Faculty Publications - Archive

The principle of competitive exclusion is well established for multiple populations competing for the same resource, and simple models for multistrain infection exhibit it as well when cross-immunity precludes coinfections. However, multiple hosts provide niches for different pathogens to occupy simultaneously. This is the case for the vector-borne parasite Trypanosoma cruzi in overlapping sylvatic transmission cycles in the Americas, where it is enzootic. This study uses cycles in the USA involving two different hosts but the same vector species as a context for the study of the mechanisms behind the communication between the two cycles. Vectors dispersing in search of …

World’S Largest Macroalgal Blooms Altered Phytoplankton Biomass In Summer In The Yellow Sea: Satellite Observations, Qianguo Xing, Chuanmin Hu, Danling Tang, Liqiao Tian, Shilin Tang, Xiao Hua Wang, Mingjing Lou, Xuelu Gao

Marine Science Faculty Publications

Since 2008, the world’s largest blooms of the green macroalgae, Ulva prolifera, have occurred every summer in the Yellow Sea, posing the question of whether these macroalgal blooms (MABs) have changed the phytoplankton biomass due to their perturbations of nutrient dynamics. We have attempted to address this question using long-term Moderate Resolution Imaging Spectroradiometer (MODIS) observations. A new MODIS monthly time-series of chlorophyll-a concentrations (Chl-a, an index of phytoplankton biomass) was generated after removing the macroalgae-contaminated pixels that were characterized by unexpectedly high values in the daily Chl-a products. Compared with Chl-a during July of 2002–2006 (the pre-MAB period), Chl-a …

Early Childhood Development And The Social Determinants Of Health Inequities: A Review Of The Evidence, Tim Moore, Myfanwy Mcdonal, Harriet Mchugh-Dillon

Mickey Leland Center Information Portal

This report focuses on early childhood development and the social determinants of health inequities. It is one of eight reviews of evidence commissioned by VicHealth to support the use of a planning tool for health promotion policy and practice in Victoria, known as Fair Foundations.

Wintering Bald Eagle Count Trends In The Conterminous United States, 1986-2010, Wade L. Eakle, Laura Bond, Mark R. Fuller, Richard A. Fischer, Karen Steenhof

Biomedical Research Institute Publications and Presentations

We analyzed counts from the annual Midwinter Bald Eagle Survey to examine state, regional, and national trends in counts of wintering Bald Eagles (Haliaeetus leucocephalus) within the conterminous 48 United States from 1986 to 2010. Using hierarchical mixed model methods, we report trends in counts from 11 729 surveys along 844 routes in 44 states. Nationwide Bald Eagle counts increased 0.6% per yr over the 25-yr period, compared to an estimate of 1.9% per yr from 1986 to 2000. Trend estimates for Bald Eagles were significant (P ≤ 0.05) and positive in the northeastern and northwestern U.S. …

A Biosystematic View Of Civilizations: Western Europe And Japan Before And After The Industrial Revolution, Kunio Kawamura

Comparative Civilizations Review

No abstract provided.

Cerebral Predestination? A Review Of Ccr No. 72, Leland Conley Barrows

Comparative Civilizations Review

No abstract provided.

Law School Record, Vol. 62, No. 1 (Fall 2015), Law School Record Editors

Law School Record

• "From More to More": Five Years of Growth under Dean Michael Schill
• Making of a MOOC
• "We Can Contribute to the Larger Society Precisely Because We are Scholars"
• The International Innovation Corps: Solving Problems in India with UChicago Talent
• Bringing the Law School to High School
• Reviewing with Thought: The New Rambler Review
• Exploring a River of Ideas with the Clinical Faculty
• Graduation 2015
• Message from the Dean

Ruby-Throated Hummingbird Nest Success In Northwest Tennessee, T. David Pitts

The Migrant - Tennessee Ornithological Society

No abstract provided.

Petrology, Palynology, And Geochemistry Of Gray Hawk Coal (Early Pennsylvanian, Langsettian) In Eastern Kentucky, Usa, James C. Hower, Courtland F. Eble, Jennifer M. K. O'Keefe, Shifeng Dai, Peipei Wang, Panpan Xie, Jingjing Liu, Colin R. Ward, David French

Center for Applied Energy Research Faculty and Staff Publications

This study presents recently collected data examining the organic petrology, palynology, mineralogy and geochemistry of the Gray Hawk coal bed. From the Early Pennsylvanian, Langsettian substage, Gray Hawk coal has been mined near the western edge of the eastern Kentucky portion of the Central Appalachian coalfield. While the coal is thin, rarely more than 0.5-m thick, it has a low-ash yield and a low-S content, making it an important local resource. The Gray Hawk coal palynology is dominated by Lycospora spp., and contains a diverse spectrum of small lycopods, tree ferns, small ferns, calamites, and gymnosperms. The maceral assemblages show …

Design, Synthesis And Evaluation Of Bivalent Inhibitors Of Trehalose-6-Phosphate Phosphatase, Chunliang Liu

Chemistry and Chemical Biology ETDs

The D-glucose disaccharide α, α-D-trehalose is synthesized by a variety of bacteria, fungi, plants and invertebrates to support cell survival by functioning as a fuel, a metabolic regulator or a protectant against environmental stress. Five different trehalose biosynthetic pathways are known to exist, one of which, the OtsA/OtsB pathway is common among pathogenic bacteria and fungi and is also found in parasitic nematodes. Previously reported otsA and otsB gene knockout (or knockdown) experiments have shown that both pathway enzymes are essential for M. tuberculosis cell growth and host colonization. RNAi gene silencing carried out in the nematode model system Caenohabditis …

Mining Public Databases For Discovery Of Structure And Function Within The Hotdog-Fold Thioesterase And Had Phosphatase Enzyme Families, Sarah Toews Keating

Chemistry and Chemical Biology ETDs

For my doctoral work, I have developed strategies to mine public databases for data that can be used to infer structural and functional information for the hotdog-fold and HADSF superfamilies. For the hotdog-fold superfamily, I used curated and automatically applied annotations of structure, taxonomic lineage, function, and subfamily membership from the UniProtKB, gene context and taxonomic information from the NCBI, and the results of several in-depth explorations of subfamily/function and structural class membership. Based on the distribution of the aforementioned annotations mapped onto a sequence similarity network (SSN), I applied structural assignments to sequences and/or specific function/subfamily assignments to ~143,000 …

Case Studies Of The Hot Dog-Fold And Acyl-Adenylate-Forming Superfamilies: Characterizing The Importance Of Functional Divergence In Cellular Metabolism, Lucas R. Zimney

Chemistry and Chemical Biology ETDs

Some of the biggest contributors to cellular respiration (and cellular metabolism in general) are acyl-CoA derivatives, a subclass of biological thioesters. Known to function in a variety of pathways, the regulation of their formation and breakdown are critical, carried about by acyl-CoA synthetases and thioesterases, respectively. The work reported within this dissertation will focus on functional divergence within two enzyme superfamilies -- the hot dog-fold and acyl-adenylate-forming superfamilies — and can be broken down into two main parts. Part one will look at tracking the functional divergence within the hot dog-fold superfamily thioesterases. A highly evolved thioesterase, flK, has been …

Improving Attitude Towards Green Environment Awareness Through The Slgea-Code Module, A.R. Rose Amnah

Research Publications (2011 to 2015)

This paper is part of a large study which was on developing a green environment awareness module using QRCode. My main focus of the study was on the development of the module. In this paper, I focus on the evalution phase of the module after it was taught by a teacher to two form four classes. The aim of the evaluation isto test whether students attitude can be nurtured to behave, act and react towards conservation of the green environment usingthe module. The researcher developed Green Environment Awareness Module with QR-Code (SLGEA-Code) as a self-learning and- mobile learning instructional approach. …

An Umbrella In A Hurricane: Cyber Technology And The December 2013 Amendment To The Wassenaar Arrangement, Innokenty Pyetranker

Northwestern Journal of Technology and Intellectual Property

Scenes of near-apocalyptic devastation resulting from good software gone bad are no longer the stuff of science fiction flicks starring bodybuilders-cum-governors. Lightning-fast technological progress and the ubiquity of the Internet have made it easy for our imaginations, as well as our political leaders, to conjure up realistic images of cyber nightmares come true. Now that fears about what lurks inside cyberspace have gone mainstream, I examine one action ostensibly aimed to allay such fears: the December 2013 amendment to the Wassenaar Arrangement on Export Controls for Conventional Arms and Dual-Use Goods and Technologies (commonly known as the Wassenaar Arrangement). My …

Profibrotic Role For Interleukin-4 In Cardiac Remodeling And Dysfunction, Hongmei Peng, Zeyd Sarwar, Xiao-Ping Yang, Edward L. Peterson, Jiang Xu, Brana Janic, Nadia Rhaleb, Oscar A. Carretero, Nour-Eddine Rhaleb

Hypertension and Vascular Research Articles

Elevated interleukin-4 (IL-4) levels are associated with cardiac fibrosis in hypertension and heart failure in both patients and experimental animals. We hypothesized that chronically elevated IL-4 induces cardiac fibrosis, resulting in a predisposition of the heart to angiotensin II-induced damage. Wild-type Balb/c (WT, high circulating IL-4) and IL-4-deficient Balb/c mice (IL-4(-/-)) were used. WT mice exhibited cardiac fibrosis (evidenced by an increase in expression of procollagen genes/interstitial collagen fraction), enlarged left ventricle chamber, and declined cardiac function associated with a greater number of mast cells and macrophages in the heart compared with IL-4(-/-). In contrast, IL-4(-/-) mice had normal cardiac …

Food Studies Book Club Fresh A Perishable History, Sept. 10, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Determination Of Triapine, A Ribonucleotide Reductase Inhibitor, In Human Plasma By Liquid Chromatography Tandem Mass Spectrometry, Ye Feng, Charles A. Kunos, Yan Xu

Chemistry Faculty Publications

Triapine is an inhibitor of ribonucleotide reductase (RNR). Studies have shown that triapine significantly decreases the activity of RNR and enhanced the radiation-mediated cytotoxicity in cervical and colon cancer. In this work, we have developed and validated a selective and sensitive LC-MS/MS method for the determination of triapine in human plasma. In this method, 2-[(3-fluoro-2-pyridinyl)methylene] hydrazinecarbothioamide (NSC 266749) was used as the internal standard (IS); plasma samples were prepared by deproteinization with acetonitrile; tripaine and the IS were separated on a Waters Xbridge Shield RP18 column (3.5 µm; 2.1 × 50 mm) using a mobile phase containing 25.0% methanol and …

Crowdsourcing Science: How Amazon's Mechanical Turk Is Becoming A Research Tool, Staff

Browse All News

No abstract provided.

Characterization Of Electrophorectic Separations On A Cellulose Paper-Microfluidic Chip, Kyle Robert Fast

Master's Theses

The purpose of this thesis project is to demonstrate the ability to utilize electrophoresis in a cellulose paper microfluidic chip to manipulate charged particles. Materials were selected and a manufacturing protocol was created to successfully apply the electric field onto the paper chip. Experiments were performed to characterize the separation rates for charged, colorimetric dye, Orange G in the membrane as a function of an applied electric field, dye concentration, and distance traveled. The experiments confirmed that the electric field can be applied to the chip and particle separation rates were characterized. Next, the determined rates results were used to …

Demographics And Transfer Of Escherichia Coli Within Bos Taurus Populations, Joshua Ryan Dillard

Master's Theses

In the United States, symptoms caused by pathogenic strains of Escherichia coli are on the rise. A major source of these pathogenic strains is the E. coli in the digestive tract of cattle. The purpose of this project was to determine if E. coli are transferred between individuals of the same species and if interspecies transmission is possible. Proximity of cattle was also studied as a contributing factor to the transfer of E. coli. To accomplish this goal, E. coli isolates from cattle and cohabitating ground squirrels were compared through a new method of bacterial strain typing called pyroprinting. …

Effects Of Testosterone On The Spatial Ecology, Coloration, And Brain Regions In Western Fence Lizards, Sceloporus Occidentalis, Rachel Catharine Wilson

Master's Theses

An organism’s spatial ecology allows for access to essential resources such as food, mates, and escape from predators. Home range size, or the total area an organism inhabits, varies in relation to numerous factors including seasonality. During the breeding season, home range size increases in males across taxa. In addition, males usually also have larger home range sizes than females. This implicates testosterone (T) as a possible mediator of this relationship. Indeed, T causes an increase in home range size of males in numerous species of lizards. In addition to T causing an increase in home range size, it also …

A Unique 5' Translation Element Discovered In Triticum Mosaic Virus, Robyn Roberts, Jincan Zhang, Laura K. Mayberry, Satyanarayana Tatineni, Karen S. Browning, Aurelie M. Rakotondrafara

Department of Plant Pathology: Faculty Publications

Several plant viruses encode elements at the 5' end of their RNAs, which, unlike most cellular mRNAs, can initiate translation in the absence of a 5' m7GpppG cap. Here, we describe an exceptionally long (739-nucleotide [nt]) leader sequence in triticum mosaic virus (TriMV), a recently emerged wheat pathogen that belongs to the Potyviridae family of positive-strand RNA viruses. We demonstrate that the TriMV 5' leader drives strong cap-independent translation in both wheat germ extract and oat protoplasts through a novel, noncanonical translation mechanism. Translation preferentially initiates at the 13th start codon within the leader sequence independently of eIF4E but involves …

Unh Welcomes New Faculty, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Daily Eastern News: September 01, 2015, Eastern Illinois University

September

No abstract provided.

Hydrological Partitioning In The Critical Zone: Recent Advances And Opportunities For Developing Transferable Understanding Of Water Cycle Dynamics, Paul D. Brooks, Jon Chorover, Ying Fan, Sarah E. Godsey, Reed M. Maxwell, James P. Mcnamara, Christina Tague

Geosciences Faculty Publications and Presentations

Hydrology is an integrative discipline linking the broad array of water-related research with physical, ecological, and social sciences. The increasing breadth of hydrological research, often where subdisciplines of hydrology partner with related sciences, reflects the central importance of water to environmental science, while highlighting the fractured nature of the discipline itself. This lack of coordination among hydrologic subdisciplines has hindered the development of hydrologic theory and integrated models capable of predicting hydrologic partitioning across time and space. The recent development of the concept of the critical zone (CZ), an open system extending from the top of the canopy to the …

Clinical Significance Of The Integrin Α6Β4 In Human Malignancies, Rachel L Stewart, Kathleen L O'Connor

Pathology and Laboratory Medicine Faculty Publications

Integrin α6β4 is a cellular adhesion molecule that binds to laminins in the extracellular matrix and nucleates the formation of hemidesmosomes. During carcinoma progression, integrin α6β4 is released from hemidesmosomes, where it can then signal to facilitate multiple aspects of tumor progression including sustaining proliferative signaling, tumor invasion and metastasis, evasion of apoptosis, and stimulation of angiogenesis. The integrin achieves these ends by cooperating with growth factor receptors including EGFR, ErbB-2, and c-Met to amplify downstream pathways such as PI3K, AKT, MAPK, and the Rho family small GTPases. Furthermore, it dramatically alters the transcriptome …