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With Marriage On The Decline And Cohabitation On The Rise, What About Marital Rights For Unmarried Partners?, Lawrence W. Waggoner

Law & Economics Working Papers

Part I of this paper uses recent government data to trace the decline of marriage and the rise of cohabitation in the United States. Between 2000 and 2010, the population grew by 9.71%, but the husband and wife households only grew by 3.7%, while the unmarried couple households grew by 41.4%. A counter-intuitive finding is that the early 21st century data show little correlation between the marriage rate and economic conditions. Because of the Supreme Court’s decision in Obergefell v. Hodges (2015), same-sex marriage is now universally available to same-sex couples. Part I considers the impact of same-sex marriage on …

In Vitro Mutational And Bioinformatics Analysis Of The M71 Odorant Receptor And Its Superfamily, Jaclyn Bubnell, Sophie Jamet, Delia Tomoiaga, Charlotte D’Hulst, Konstantinos Krampis, Paul Feinstein

Publications and Research

We performed an extensive mutational analysis of the canonical mouse odorant receptor (OR) M71 to determine the properties of ORs that inhibit plasma membrane trafficking in heterologous expression systems. We employed the use of the M71::GFP fusion protein to directly assess plasma membrane localization and functionality of M71 in heterologous cells in vitro or in olfactory sensory neurons (OSNs) in vivo. OSN expression of M71::GFP show only small differences in activity compared to untagged M71. However, M71::GFP could not traffic to the plasma membrane even in the presence of proposed accessory proteins RTP1S or mβ2AR. To ask if ORs contain …

The Cowl - V.80 - N.7 - Oct 29, 2015

The Cowl

The Cowl - student newspaper of Providence College. Volume 80 - No. 7 - October 29, 2015. 24 pages.

In Vitro Mutational Analysis Of The Β2 Adrenergic Receptor, An In Vivo Surrogate Odorant Receptor, Sophie Jamet, Jaclyn Bubnell, Patrick Pfister, Delia Tomoiaga, Matthew E. Rogers, Paul Feinstein

Publications and Research

Many G-protein coupled receptors (GPCRs), such as odorant receptors (ORs), cannot be characterized in heterologous cells because of their difficulty in trafficking to the plasma membrane. In contrast, a surrogate OR, the GPCR mouse β2-adrenergic-receptor (mβ2AR), robustly traffics to the plasma membrane. We set out to characterize mβ2AR mutants in vitro for their eventual use in olfactory axon guidance studies. We performed an extensive mutational analysis of mβ2AR using a Green Fluorescent Protein-tagged mβ2AR (mβ2AR::GFP) to easily assess the extent of its plasma membrane localization. In order to characterize mutants for their ability to successfully transduce ligand-initiated signal cascades, we …

Changes In Litter Quality Caused By Simulated Nitrogen Deposition Reinforce The N-Induced Suppression Of Litter Decay, Linda T. A. Van Diepen, Serita D. Frey, Christopher M. Sthultz, Eric W. Morrison, Rakesh Minocha, Anne Pringle

Faculty Publications

Rates of nitrogen (N) deposition are increasing in industrialized and rapidly developing nations. Simulated N deposition suppresses plant litter decay rates, in particular for low quality (high lignin) litter. Litter quality is a primary driver of litter decomposition; however, it is not clear how changes in litter quality caused by long-term ecosystem exposure to chronic N additions interact with altered soil N-availability to influence litter decay dynamics. To document the effects of simulated N deposition on litter quality, we conducted a meta-analysis of available litter nutrient data from simulated N deposition experiments in temperate forests. To directly test whether changes …

No Effect Of Host Species On Phenoloxidase Activity In A Mycophagous Beetle, Vincent A. Formica, Amanda Kar-Men Chan , '16

Biology Faculty Works

Ecological immunology is an interdisciplinary field that helps elucidate interactions between the environment and immune response. The host species individuals experience have profound effects on immune response in many species of insects. However, this conclusion comes from studies of herbivorous insects even though species of mycophagous insects also inhabit many different host species. The goal of this study was to determine if fungal host species as well as individual, sex, body size, and host patch predict one aspect of immune function, phenoloxidase activity (PO). We sampled a metapopulation of Bolitotherus cornutus, a mycophagous beetle in southwestern Virginia. B. cornutus live …

Continuous 1.3-Million-Year Record Of East African Hydroclimate, And Implications For Patterns Of Evolution And Biodiversity, Robert P. Lyons, Christopher A. Scholz, Andrew S. Cohen, John W. King, Erik T. Brown, Sarah J. Ivory, Thomas C. Johnson, Alan L. Deino, Peter N. Reinthal, Michael M. Mcglue, Margaret W. Blome

Graduate School of Oceanography Faculty Publications

The transport of moisture in the tropics is a critical process for the global energy budget and on geologic timescales, has markedly influenced continental landscapes, migratory pathways, and biological evolution. Here we present a continuous, first-of-its-kind 1.3-My record of continental hydroclimate and lake-level variability derived from drill core data from Lake Malawi, East Africa (9–15° S). Over the Quaternary, we observe dramatic shifts in effective moisture, resulting in large-scale changes in one of the world’s largest lakes and most diverse freshwater ecosystems. Results show evidence for 24 lake level drops of more than 200 m during the Late Quaternary, including …

The Pacifican October 29, 2015, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

Quaker Campus, October 29, 2015 (Vol. 102, Issue 8), Whittier College

Quaker Campus

No abstract provided.

Novel Loci Associated With Usual Sleep Duration: The Charge Consortium Genome-Wide Association Study, D. J. Gottlieb, K. Hek, T. H. Chen, N. F. Watson, G. Eiriksdottir, E. M. Byrne, M. Cornelis, S. C. Warby, S. Bandinelli, John Blangero

School of Medicine Publications

Usual sleep duration is a heritable trait correlated with psychiatric morbidity, cardiometabolic disease and mortality, although little is known about the genetic variants influencing this trait. A genome-wide association study (GWAS) of usual sleep duration was conducted using 18 population-based cohorts totaling 47 180 individuals of European ancestry. Genome-wide significant association was identified at two loci. The strongest is located on chromosome 2, in an intergenic region 35- to 80-kb upstream from the thyroid-specific transcription factor PAX8 (lowest P=1.1 × 10 -9). This finding was replicated in an African-American sample of 4771 individuals (lowest P=9.3 × 10 -4). The strongest …

Dna-Repair Defects And Olaparib In Metastatic Prostate Cancer., Joaquin Mateo, Suzanne Carreira, Shahneen Sandhu, Susana Miranda, Helen Mossop, Raquel Perez-Lopez, Daniel Nava Rodrigues, Dan Robinson, Aurelius Omlin, Nina Tunariu, Gunther Boysen, Nuria Porta, Penny Flohr, Alexa Gillman, Ines Figueiredo, Claire Paulding, George Seed, Suneil Jain, Christy Ralph, Andrew Protheroe, Syed Hussain, Robert Jones, Tony Elliott, Ursula Mcgovern, Diletta Bianchini, Jane Goodall, Zafeiris Zafeiriou, Chris T Williamson, Roberta Ferraldeschi, Ruth Riisnaes, Bernardette Ebbs, Gemma Fowler, Desamparados Roda, Wei Yuan, Yi-Mi Wu, Xuhong Cao, Rachel Brough, Helen Pemberton, Roger A'Hern, Amanda Swain, Lakshmi P Kunju, Rosalind Eeles, Gerhardt Attard, Christopher J Lord, Alan Ashworth, Mark A Rubin, Karen E Knudsen, Felix Y Feng, Arul M Chinnaiyan, Emma Hall, Johann S De Bono

Department of Medicine Faculty Papers

BACKGROUND: Prostate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We hypothesized that metastatic, castration-resistant prostate cancers with DNA-repair defects would respond to poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibition with olaparib.

METHODS: We conducted a phase 2 trial in which patients with metastatic, castration-resistant prostate cancer were treated with olaparib tablets at a dose of 400 mg twice a day. The primary end point was the response rate, defined either as an objective response according to Response Evaluation Criteria in Solid Tumors, version 1.1, or as a reduction of at least 50% in the …

Prediction Of The Optimum Binder Content Of Open-Graded Friction Course Mixtures Using Digital Image Processing, Yolibeth Mejias De Pernia

USF Tampa Graduate Theses and Dissertations

Florida Department of Transportation (FDOT) has been using Open Graded Friction Course (OGFC) mixture to improve skid resistance of asphalt pavements under wet weather. The OGFC mixture design strongly depends on the Optimum Binder Content (OBC) which represents if the mixture has sufficient bonding between the aggregate and asphalt binder. At present, the FDOT designs OGFC mixtures using a pie plate visual draindown method (FM 5-588). In this method, the OBC is determined based on visual inspection of the asphalt binder draindown (ABD) configuration of three OGFC samples placed on pie plates with pre-determined trial asphalt binder contents (AC). The …

Getting Ahead: Socio-Economic Mobility, Perceptions Of Opportunity For Socio-Economic Mobility, And Attitudes Towards Public Assistance In The United States, Alissa Klein

USF Tampa Graduate Theses and Dissertations

In this research I first examine how Americans’ perceptions of what it takes to get ahead are influenced by their income and then compare those perceptions to measured levels of intergenerational socio-economic mobility. By better understanding these relationships I hope to gain insight into the paths people see to upward mobility, how this varies by income, and to what extent this belief is reflected in past mobility measurements. Additionally, I compare perceptions of what it takes to get ahead with responses regarding attitudes towards public assistance. The results of such a comparison could have important implications for public policy.

The …

High-Solids Anaerobic Digestion Of The Organic Fraction Of Municipal Solid Waste State Of The Art, Outlook In Florida, And Enhancing Methane Yields From Lignocellulosic Wastes, Gregory Richard Hinds

USF Tampa Graduate Theses and Dissertations

Anaerobic digestion (AD) is a biotechnology that employs natural microbial metabolism under oxygen-free conditions to stabilize organic waste. AD has been shown to be the most environmentally sustainable technology for treating the organic fraction of municipal solid waste (OFMSW), as it allows for the recovery of energy and nutrients from the waste. AD of OFMSW also saves landfill space and reduces leachate generation and fugitive methane emissions from landfills. High-solids AD (HS-AD) technologies (those designed to process feedstocks with >15% total solids content) have been shown to yield additional benefits when compared with liquid AD (L-AD) for treating OFMSW, including …

2015 October 28 -- Agenda And Attachments

Agendas and Minutes

No abstract provided.

Removing Inter-Subject Technical Variability In Magnetic Resonance Imaging Studies, Jean-Philippe Fortin, Elizabeth M. Sweeney, John Muschelli, Ciprian M. Crainiceanu, Russell T. Shinohara, Alzheimer’S Disease Neuroimaging Initiative

UPenn Biostatistics Working Papers

Magnetic resonance imaging (MRI) intensities are acquired in arbitrary units, making scans non-comparable across sites and between subjects. Intensity normalization is a first step for the improvement of comparability of the images across subjects. However, we show that unwanted inter-scan variability associated with imaging site, scanner effect and other technical artifacts is still present after standard intensity normalization in large multi-site neuroimaging studies. We propose RAVEL (Removal of Artificial Voxel Effect by Linear regression), a tool to remove residual technical variability after intensity normalization. As proposed by SVA and RUV [Leek and Storey, 2007, …

Second Year Results From Razor C.O.A.C.H., Sarah Moore, Josh Raney, Gary W. Ritter, Kristin K. Higgins

Arkansas Education Reports

In this paper, we present the results of a random assignment evaluation on the Razor C.O.A.C.H. (Creating Opportunities for Arkansan’s Career Hopes) program. As the program started in the 2012-13 school year, this evaluation analyzes the impact of the program in its second year of operation and includes two cohorts of students. The focus of the comprehensive evaluation is the impacts of the program on students’ academic outcomes, short-term noncognitive outcomes, short-term college and career readiness outcomes, and post-secondary outcomes.

The Collegian: October 28, 2015, The Collegian Staff

The Collegian, 2015-2016

Volume 131
Issue 9

Volume 53, Number 11: October 28, 2015, University Of North Dakota

University Letter Archive

No abstract provided.

The Anchor, Volume 129.08: October 28, 2015, Hope College

The Anchor: 2015

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Mexico Among 12 Countries To Sign Trans-Pacific Partnership; Intellectual Property Section A Concern, Carlos Navarro

SourceMex

No abstract provided.

Grad Students Take Bio Bonanza To Local Schools, Libraries, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

2015 Program, Office Of Academic Affairs

Programs

A university is more than an amalgamation of several colleges. It also is an organization which celebrates the full richness of faculty contributions including those vital and exciting contributions in research, scholarship and creative activity within their disciplines. These contributions come in many forms: journal articles, book chapters, monographs, art works, music compositions, performances of many varieties and a host of others. Funded research contributions are similarly varied. Through such activities, faculty members stay at the growing edges of their fields, and in so doing, they enrich their intellectual lives as well as those of their students.

Once again, I …

Running And Tumbling With E. Coli In Polymeric Solutions, Alison E. Patteson, Arvind Gopinath, Mark Goulian, Paulo E. Arratia

Physics - All Scholarship

Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and-tumble dynamics of the bacterium E. coli in polymeric solutions. We find that even small amounts of polymer in solution can drastically change E. colidynamics: cells tumble less and their velocity increases, leading to an enhancement in cell translational diffusion and a sharp decline in rotational diffusion. We show that suppression of tumbling is due to fluid viscosity while the enhancement in swimming speed is mainly due to fluid elasticity. Visualization of single fluorescently labeled DNA polymers reveals that the …

Uc Transcript 2015-10-28, Northern Illinois University

University Council Archives

No abstract provided.

Center For The Humanities Announces 2016-2017 Faculty Fellows, Katie Umans

UNH Today Archive

No abstract provided.

Fine-Grained Bacterial Compositional Analsysis Of The Port Everglades Inlet (Broward County, Fl) Microbiome Using High Throughput Dna Sequencing, Lauren M. O'Connell

HCNSO Student Theses and Dissertations

Port Everglades Inlet is one of the busiest ports in the country and is a point source of pollution to surrounding beaches and offshore corals from heavy boat traffic and urban runoff. Understanding fluctuations of bacterioplankton communities in major port inlets is important due to their impacts on surrounding marine environments. To understand annual microbial fluctuations, the 16s rRNA V4 hypervariable region was sequenced using Illumina high-throughput DNA sequencing technology. Surface samples were taken weekly for one year to generate baseline fluctuations in the microbial community. Total reads of 1.4 million were generated with a final count of 16,384 Operational …

Effect Of Matrix On Glassy Carbohydrate Products Comprising Sweet Orange Oil, Chang Dawei, Liu Shuxing, Liu Ning

Food and Machinery

Encapsulation in glassy carbohydrates via extrusion is the low temperature technology and considered to be suitable for encapsulating heat-sensitive materials. The selection of matrix is the important factor. The temperatures of extruder barrel were T₁ (65 ℃)，T₂ (85 ℃)，T₃ (105 ℃) and T₄ (95 ℃). Screw speed was 60 r/min and the feeding speed was 1.2 kg/h. The effects of matrix including maltodextrin, maltodextrin added sucrose and maltodextrin added modified starch on the extrudates was investigated. The results showed that the extruded products were the glassy state. The glass transition temperature (T_g) of the …

Effect Of Xanthan On Gelling Properties Of Myofibrillar Protein-Soy Protein Composite With Various Salt Levels, Lin Yuhui, Li Pengpeng, He Zhiyong, Qin Fang, Wu Shengfang, Chen Jie

Food and Machinery

No abstract provided.