Digital Commons Network^™

Spatial Incidence Of Adult Obesity In The State Of Alabama, Mary G. Odhiambo

Theses

No abstract provided.

Technology And The Guilty Mind: When Do Technology Providers Become Criminal Accomplices, Benton Martin, Jeremiah Newhall

Journal of Criminal Law and Criminology

The creators of today’s most successful technologies share an important willingness to push the envelope—a drive that propels digital industry forward. This same drive, however, can lead some technology purveyors to push the limits of legality or even become scofflaws in their pursuit of innovation or (more often) profit. The United States must figure out how to harness the important creative force at the heart of the hacker ethic while still deterring destructive criminal wrongdoers. Because it is often courts that must answer this question, it is essential to examine the legal doctrines prosecutors use to sweep up technology providers. …

Maternal And Paternal Imprisonment And Children's Social Exclusion In Young Adulthood, Holly Foster, John Hagan

Journal of Criminal Law and Criminology

The United States has entered its fourth decade of high imprisonment levels. It is now possible to assess the impact of parental imprisonment on children who have completed the transition to adulthood. We elaborate the role of parental incarceration from a life course perspective on intergenerational social exclusion in young adulthood. The National Longitudinal Study of Adolescent Health [Add Health] representatively sampled the historically unique national cohort born in the 1980s, during the onset of mass incarceration. Four waves of the Add Health survey provide a valuable moving window on incarcerated parents and the transitions of their children from adolescence, …

An Ideological Odyssey: Evolution Of A Reformer, Rob Warden

Journal of Criminal Law and Criminology

No abstract provided.

The Unindicted Co-Ejaculator And Necrophilia: Addressing Prosecutors' Logic-Defying Responses To Exculpatory Dna Results, Jacqueline Mcmurtrie

Journal of Criminal Law and Criminology

This article addresses a prosecutor’s development of new and bizarre theories, particularly in cases involving confession evidence, to explain away exculpatory DNA results. In Juan Rivera’s case, the prosecutor’s theory for why sperm found inside the 11-year-old victim on the day she was murdered did not belong to Rivera was that she had sex with someone before Rivera came along and raped (but did not ejaculate) and murdered her. The unnamed-lover theory is used so often by prosecutors that it has a moniker: “the unindicted co-ejaculator.” In the case of the Dixmoor Five, teenagers convicted of the rape and murder …

Paternal Incarceration And Adolescent Well-Being: Life Course Contingencies And Other Moderators, Raymond R. Swisher, Unique R. Shaw-Smith

Journal of Criminal Law and Criminology

No abstract provided.

Missing The Mark: Gun Control Is Not The Cure For What Ails The U.S. Mental Health System, Carolyn Reinach Wolf, Jamie A. Rosen

Journal of Criminal Law and Criminology

No abstract provided.

Accentuating The Positive Or Eliminating The Negative? Paternal Incarceration And Caregiver-Child Relationship Quality, Sara Wakefield

Journal of Criminal Law and Criminology

No abstract provided.

Describing The Health Care Needs Of School-Age Children In Sub-Saharan Africa In Order To Develop A Model Of A Nurse-Run School-Based Health Clinic, Bonnie Tong

Yale School of Nursing Digital Theses

Objective: Rural Kenya is affected by health disparities and poor health outcomes among school-age children. This paper identifies gaps in health care among school-aged children in rural Kenya, in order to identify a health care model to meet those gaps.

Design: The results of a systematic review on the health care needs were triangulated with field notes from interviews of stakeholders in a rural Kenyan village. Needs were then compared with currently available health care resources to identify gaps.

Sample: Multiple databases were searched to identify relevant articles published between the years 2000- 2014. Interviews were conducted with health workers, …

Prenatal Medication Use And Autistic Behaviors In A South Korean Cohort, John Keaney

Public Health Theses

Autism spectrum disorder (ASD) is thought to result from a combination of genetic and environmental factors, yet a specific cause remains unknown. In this study, exposure and outcome data from a South Korean cohort (N=3,711) were analyzed to investigate the possibility of an environmental contribution to autism etiology. No significant association was observed between use of prenatal medications and autistic behaviors, as measured by Korean versions of both the Autism Spectrum Screening Questionnaire (ASSQ; OR 1.20, 95% CI 0.95–1.51) and the Social Responsiveness Scale (SRS; OR 0.98, 95% CI 0.78–1.25). Similarly, no significant associations were observed when use of prenatal …

Spatial Distribution And Sociodemographic Composition Of High Grade Cervical Lesion Clusters In Connecticut 2008-2013, Aref Senno

Public Health Theses

Introduction: HPV is necessary for the development of invasive cervical cancer. There were 530,000 cases and 275,000 deaths attributable to cervical cancer in 2008. Since the introduction of HPV vaccines in 2006, the incidence of high grade cervical lesions (HGCL)—precancerous lesions which may develop into cervical cancer—has decreased significantly. Some changing sociodemographic trends in disease burden have been previously reported since 2008.

Objectives: The objectives of this analysis were to identify regions of Connecticut with high rates of HGCLs and to describe how trends of disease changed over time in the post-vaccine era.

Methods: This is a descriptive analysis of …

Influenza And Asthma Hospitalizations In Nyc From 2002-2012, Pauline Trinh

Public Health Theses

INTRODUCTION: The literature has focused primarily on rhinoviruses as the major determinant of asthma exacerbations. The association between other respiratory viruses such as influenza and asthma exacerbations is not well characterized and further understanding can better inform prevention strategies to reduce influenza-related asthma.

OBJECTIVES: The primary objective of this study is to determine whether asthma hospitalizations of children and adults in the five boroughs of New York City is correlated with influenza hospitalizations temporally and spatially and whether these correlations differ by county or age.

METHODS: A times series regression analysis was performed using influenza hospitalizations as the explanatory series …

Modeling Sensorimotor Learning In Lida Using A Dynamic Learning Rate, D. Dong, S. Franklin

CCRG Papers

No abstract provided.

A New Action Execution Module For The Learning Intelligent Distribution Agent (Lida): The Sensory Motor System, D. Dong, S. Franklin

CCRG Papers

No abstract provided.

Constrained Incrementalist Moral Decision Making For A Biologically Inspired Cognitive Architecture, T. Madl, S. Franklin

CCRG Papers

No abstract provided.

Soil Biochemical Properties In Brown And Gray Mine Soils With And Without Hydroseeding, C Thomas, A Sexstone, J Skousen

Faculty & Staff Scholarship

Surface coal mining in the eastern USA disturbs hundreds of hectares of land every year and removes valuable and ecologically diverse eastern deciduous forests. Reclamation involves restoring the landscape to approximate original contour, replacing the topsoil, and revegetating the site with trees and herbaceous species to a designated post-mining land use. Re-establishing an ecosystem of ecological and economic value as well as restoring soil quality on disturbed sites are the goals of land reclamation, and microbial properties of mine soils can be indicators of restoration success. Reforestation plots were constructed in 2007 using weathered brown sandstone or unweathered gray sandstone …

Understanding The Structure-Function Relationships Between Monoamine Neurotransmitter Transporters And Their Cognate Ions And Ligands, Bruce Felts

Theses and Dissertations

The SLC6 family of secondary active transporters is made up of integral membrane solute carrier proteins characterized by the Na+-dependent translocation of small amino acid or amino acid-like substrates. SLC6 transporters, particularly the monoamine transporters (MATs) of serotonin, dopamine and norepinephrine, are some of the most heavily studied proteins today due to their association with a number of human diseases and disorders, making MATs a critical target for therapeutic development. In addition, MATs are directly involved in the action of drugs of abuse such as cocaine, amphetamines, and ecstasy.

Following the first cloning of a MAT gene in the early …

The Importance Of Analyzing Neighbor Competitive Response In The Target-Neighbor Experimental Design, Kevin J. Barry, Michele R. Dudash

Faculty & Staff Scholarship

No abstract provided.

Phase-Lag Synchronization In Networks Of Coupled Chemical Oscillators, Jan F. Totz, Razan Snari, Desmond Yengi, Mark R. Tinsley, Harald Engel, Kenneth Showalter

Faculty & Staff Scholarship

No abstract provided.

Protective Effects Of Erdosteine, Vitamin E, And Vitamin C On Renal Injury Induced By The Ischemia-Reperfusion Of The Hind Limbs In Rats, Rana Sirmali, Abdullah Armağan, Faruk Öktem, Efkan Uz, Aynur Kirbaş, Soner Dönmez, Haci Ramazan Yilmaz, Mesrur Selçuk Silay, Mehmet Sirmali

Turkish Journal of Medical Sciences

To compare the protective efficacy of erdosteine and vitamins C and E against renal injury caused by hind limb ischemia-reperfusion (I/R). Materials and methods: Rats were split into 4 groups: group I as the control, group II as I/R, group III as I/R + erdosteine, and group IV as I/R + vitamins C and E. Superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities and malondialdehyde (MDA) tissue levels were determined. Results: MDA levels were found comparable with the control group in groups II and III. However, they were considerably decreased in group IV when compared to group II …

A Molecular Epidemiological Investigation Of Multistate Outbreaks Of Salmonella Enteritidis From Clinical And Environmental Samples In Turkey, 2000-2010, Sümeyra Acar, Belkis Levent, Ekrem Atalan

Turkish Journal of Medical Sciences

To analyze interrelated Salmonella Enteritidis strains isolated in Turkey. Fifty-five S. Enteritidis surveillance strains were isolated from human feces and environmental samples from different regions in Turkey between 2000 and 2010. Materials and methods: Clinical isolates were selected from different outbreaks in the Turkish National Reference Laboratory. All isolates were submitted to antimicrobial susceptibility test, plasmid profile analysis, and XbaI-digested pulsed-field gel electrophoresis. Results: The strains were scanned against 20 antibiotics and for 3 of them (amikacin, ciprofloxacin, gentamicin), all strains were found to be sensitive. Five isolates had no plasmid. Most of test strains carried the 57-kb plasmid in …

Prognostic Value Of Hemostasis-Related Parameters For Prediction Of Organ Dysfunction And Mortality In Sepsis, Dunja Mihajlovic, Dajana Lendak, Gorana Mitic, Tatjana Cebovic, Biljana Draskovic, Aleksandra Novakov, Snezana Brkic

Turkish Journal of Medical Sciences

Clinical manifestations of sepsis are not caused directly by the invading pathogens, but rather mostly by systemic inflammation that leads to activation of the coagulation system. The aim of this study was to determine whether levels of hemostasis-related parameters measured in intensive care unit admissions are associated with mortality and severity in patients with sepsis. Materials and methods: Eighty-five patients who fulfilled criteria for a diagnosis of sepsis were included in our study. Platelet count, activated partial thromboplastin time (aPTT), prothrombin time (PT), thrombin time, D-dimer, and fibrinogen levels were determined within the first 24 h from sepsis onset. Differences …

Clinicopathological Importance Of Ki-67, P27, And P53 Expression In Gastric Cancer, Muhammet Çalik, Eli̇f Demi̇rci̇, Eren Altun, İlknur Çalik, Özge Beyza Gündoğdu, Nesri̇n Gürsan, Betül Gündoğdu, Mevlüt Albayrak

Turkish Journal of Medical Sciences

To assess the prognostic value of Ki-67, p27, and p53 immunoreactivity in human gastric cancer. Materials and methods: A total of 84 patients with gastric cancer participated in our study. We categorized tumors as intestinal and diffuse types, with reference to Lauren's classification. Ki-67, p27, and p53 immunoreactivity were correlated with patient's age, tumor type, grade, lymph node status, extent of invasion, tumor-node-metastasis (TNM) stage, and survival. Results: Decreased expression of p27 (50% positivity of cells) were determined in 41 (48.8%) and 29 (36.9%) tumor specimens, respectively, and were connected with both the TNM stage (P = 0.007 and P …

Evaluation Of Autoinflammatory Disease Genes In Nasal Polyposis, Sabri̇ Köseoğlu, Kürşat Murat Özcan, Aykut İki̇nci̇oğullari, Mehmet Ali̇ Çeti̇n, Tali̇h Özdaş, Si̇bel Özdaş, Serdar Ensari̇, Haci Hüseyi̇n Dere

Turkish Journal of Medical Sciences

To investigate cold-induced autoinflammatory syndrome 1 (CIAS1) gene polymorphisms that cause autoinflammatory diseases in patients with nasal polyposis (NP). Materials and methods: The study included 30 patients diagnosed with NP and 30 healthy age-matched individuals as a control group. CIAS1 polymorphisms were assessed by DNA sequence analysis. Patients with nasal polyps and the control group were compared in terms of gene polymorphisms. Each of the 8 polymorphisms of the CIAS1 gene was analyzed separately in the patient group. Results: The most frequently observed polymorphisms in the patient group were c.732G > A in 83%, c.663C > T in 23%, and c.1308C > A …

Vitamin E Modulates Lung Oxidative Stress, Serum Copper, Zinc, And Iron Levels In Rats With Pulmonary Contusion, Mehmet Sirmali, Okan Solak, Tali̇p Çevi̇k, Rana Sirmali, Bünyami̇n Özaydin, Zeynep Gi̇ni̇ş, Yetki̇n Ağaçkiran, Namik Deli̇baş

Turkish Journal of Medical Sciences

To evaluate the effects of oxidant/antioxidant mechanisms and levels of trace elements on trauma-stimulated moderate pulmonary contusions after vitamin E administration. Materials and methods: Sixty-three male Sprague Dawley rats were used. Animals were studied in 4 groups. Vitamin E (150 mg/kg) was injected intraperitoneally 30 min after trauma and on the first and second days. Blood samples were obtained for nitric oxide (NO) levels and superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities. Zinc (Zn^{+2}), copper (Cu^{+2}), and iron (Fe^{+3}) were measured in serum. Results: Lung contusion increased serum and tissue NO levels and SOD activities and decreased GSH-Px activities …

Beraprost Sodium, A Prostacyclin (Pgi) Analogue, Ameliorateslipopolysaccharide-Induced Cellular Injury In Lung Alveolar Epithelial Cells, Si̇nan Vicil, Suat Erdogan

Turkish Journal of Medical Sciences

Human alveolar epithelial cells play a critical role in the pathogenesis of lung diseases. The objective of this study is to determine the contribution of beraprost sodium, a prostaglandin I_2 (PGI_2) analogue, to inflammatory and oxidative events in response to lipopolysaccharide (LPS) in airway epithelial cells. Materials and methods: Human pulmonary alveolar epithelial cells (A549) were pretreated with 10 µM beraprost sodium 30 min before stimulation with 1 µg/mL LPS for 24 h. The cellular viability assessments were evaluated by quantitative MTT test. Catalase activity and glutathione and lipid peroxidation levels were determined using spectrophotometric techniques. mRNA expression analyses were …

Retracted - Quantitative Study Of Epigenetic Signature In Head And Necksquamous Cell Carcinoma, Ayesha Umair, Bassel Tarakji, Alzoghaibi Ibrahim, Azzeghaibi Nasser, Alenzi Fq, Ayesha Shreen

Turkish Journal of Medical Sciences

Background/aim: The aberrant upregulation of Forkhead box protein M1 (FOXM1) plays a fundamental role in cancer initiation by perturbing stem cell differentiation. This study aims to investigate the role of FOXM1 in epigenetic modification and gene expression of target genes in primary human oral keratinocytes, squamous cell carcinoma cell lines, and head and neck squamous cell carcinoma (HNSCC) tissue biopsies. Materials and methods: A genome-wide promoter methylation microarray was used to compare HNSCC cell line (n = 8), primary human oral keratinocytes (NOK; n = 8) transduced with FOXM1 and EGFP, and HNSCC tissue biopsies (n = 3). Seventeen Foxm1B-induced …

Two Gastrointestinal Conditions With Similar Symptoms And Endoscopicappearance: Irritable Bowel Syndrome And Microscopic Colitis, Zahi̇de Şi̇mşek, Nazi̇fe Candan Tunçer, Hakan Alagözlü, Fati̇h Karaahmet, Şahi̇n Çoban, Ayşe Dursun

Turkish Journal of Medical Sciences

Background/aim: Irritable bowel syndrome (IBS) is a gastrointestinal condition characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any organic cause. This trial investigated the presence of microscopic colitis (MC) and associated factors related to MC in patients diagnosed with IBS. Materials and methods: The study group (group I) consisted of 91 consecutive patients diagnosed with IBS based on the Rome III Criteria for whom colonoscopic examination was requested. The control group (group II) had 41 patients diagnosed with IBS considered as eligible for colonoscopic investigation due to specific conditions, and for whom …

Trace Elements Levels In The Serum, Urine, And Semen Of Patients With Infertility, Hasan Sali̇h Sağlam, Hüseyi̇n Altundağ, Yavuz Tarik Ati̇k, Mustafa Şahi̇n Dündar, Öztuğ Adsan

Turkish Journal of Medical Sciences

Background/aim: Studies suggest that trace elements may have an adverse impact on male reproduction, even at low levels. We tried to investigate the relationships between these metals and semen quality in various body fluids among men with infertility. Materials and methods: A total of 255 samples of blood, semen, and urine were collected from 85 men suffering from infertility. Inductively coupled plasma-optical emission spectrometry was used for the determination of 22 trace elements. We compared the results of the semen parameters with the results of the element determinations. Results: Because of the high proportion of samples with values lower than …

Malondialdehyde And Nitric Oxide Levels And Catalase, Superoxide Dismutase, And Glutathione Peroxidase Levels In Maternal Blood During Different Trimesters Ofpregnancy And In The Cord Blood Of Newborns, Sevda Yüksel, Ayşe Arzu Yi̇ği̇t

Turkish Journal of Medical Sciences

Background/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancy with newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes. Materials and methods: Maternal blood samples were collected at 9?13, 22?26, and 36?40 weeks of gestation. Cord blood was collected at the time of delivery. Results: NO levels and GPx activity were higher in the second and third trimesters than in the first trimester. MDA level was lower in the …