Digital Commons Network^™

Parental Spatial Input During Parent-Child Interactions: A Two-Dimensional Versus A Three-Dimensional Learning Experience, Ariel Ho

Theses and Dissertations (Comprehensive)

Children’s spatial ability is predictive of their future achievement in many academic and occupational domains, including science, technology, engineering, and mathematics (STEM; e.g., Wai at el., 2009). During the early years, experiences such as hearing spatial language (e.g., Ferrara et al., 2011) and engaging in spatial activities with three-dimensional (3D) blocks or puzzles (e.g., Casey et al., 2008) are found to facilitate children’s spatial learning. Other than 3D toys, the use of two-dimensional (2D) touchscreen media (e.g., iPads^®) by young children has been on the rise (e.g., Rideout, 2013). Technology has become part of children’s daily activities and …

The Role Of Citizens In Detecting And Responding To A Rapid Marine Invasion, Steven B. Scyphers, Sean P. Powers, J. Lad Akins, J. Marcus Drymon, Charles W. Martin, Zeb H. Schobernd, Pamela J. Schofield, Robert L. Shipp, Theodore S. Switzer

University Faculty and Staff Publications

Documenting and responding to species invasions requires innovative strategies that account for ecological and societal complexities. We used the recent expansion of Indo-Pacific lionfish (Pterois volitans/miles) throughout northern Gulf of Mexico coastal waters to evaluate the role of stakeholders in documenting and responding to a rapid marine invasion. We coupled an online survey of spearfishers and citizen science monitoring programs with traditional fishery-independent data sources and found that citizen observations documented lionfish 1–2 years earlier and more frequently than traditional reef fish monitoring programs. Citizen observations first documented lionfish in 2010 followed by rapid expansion and proliferation in …

Participatory Conservation Of Coastal Habitats: The Importance Of Understanding Homeowner Decision Making To Mitigate Cascading Shoreline Degradation, Steven B. Scyphers, Steven J. Picou, Sean P. Powers

University Faculty and Staff Publications

Along densely populated coasts, the armoring of shorelines is a prevalent cause of natural habitat loss and degradation. This article explores the values and decision making of waterfront homeowners and identifies two interlinked and potentially reversible drivers of coastal degradation. We discovered that: (1) misperceptions regarding the environmental impacts and cost-effectiveness of different shoreline conditions was common and may promote armoring; and (2) many homeowners reported only altering their shorelines in response to damage caused by armoring on neighboring properties. Collectively, these findings suggest that a single homeowner’s decision may trigger cascading degradation along a shoreline, which highlights the necessity …

Some Problems In The Representation Theory Of Simple Modular Lie Algebras, Georgia Benkart, Jorg Feldvoss

University Faculty and Staff Publications

No abstract provided.

Bioethanol: Feedstock Alternatives, Pretreatments,Lignin Chemistry, And The Potential For Green Value-Added Lignin Co-Products, Ruben Michael Ceballos, N. A. Batchenkova, M.K. Y. Chan, A. X. Duffing-Romero, A. E. Nelson, S. Man

Biological Sciences Faculty Publications and Presentations

Major challenges still exist in the cost-competitive production of cellulosic ethanol. Lignocellulose deconstruction using physiochemical pretreatments continues to be the most efficient way to remove lignin and expose cellulose for enzyme-mediated sugar reduction. Recent interest in the development of “value-added” lignin co-products and the desire to reduce the use of hazardous materials has prompted a resurgence of interest in alternative lignocellulosic feedstock and research into environment-friendly biological pretreatments. This article provides an overview of bioethanol processes and economics, standard and alternative feedstocks, physiochemical and biological pretreatments, and lignin chemistry. The chemistry and mode of action of ligninolytic and cellulolytic enzymes …

On Designation Of North Korea As A State Sponsor Of Cyberterrorism, Justin L. Koplow

SMU Science and Technology Law Review

No abstract provided.

Rousseau, Fanon, And The Question Of Method In Political Theory, A Review Of Jane Anna Gordon's Creolizing Political Theory: Reading Rousseau Through Fanon, Michael Monahan

Philosophy Faculty Research and Publications

No abstract provided.

Diseases, Patients And The Epistemology Of Practice: Mapping The Borders Of Health, Medicine And Care, Michael Loughlin, Robyn Bluhm, Jonathan Fuller, Stephen Buetow, Kirstin Borgerson, Benjamin R. Lewis, Brent M. Kious

Philosophy Faculty Publications

Last year saw the 20th anniversary edition of JECP, and in the introduction to the philosophy section of that landmark edition, we posed the question: apart from ethics, what is the role of philosophy at the bedside'? The purpose of this question was not to downplay the significance of ethics to clinical practice. Rather, we raised it as part of a broader argument to the effect that ethical questions - about what we should do in any given situation - are embedded within whole understandings of the situation, inseparable from our beliefs about what is the case (metaphysics), what it …

Dividing Nature By The Joints, Chad Wiener

Philosophy Faculty Publications

Most scholars of Aristotle’s biology have accepted the view of D. M. Balme and Pierre Pellegrin that the History of Animals is devoid of any systematic classification of animals. I challenge this reading. I show that Aristotle can produce a taxonomy of animals kinds that are found in the essences of atomic species, or, to borrow from Plato, divide nature by the joints. I start from Aristotle’s positive views of division stated in APo. II.13–14 and how they imply a taxonomic order of a genus. I then develop my interpretation of how Aristotle can divide nature by the joints in …

Addressing New Skills Needed For The Automotive Industry Through A Motorsports Educational Pathway, Vukica M. Jovanovic, Mileta M. Tomovic, Alok K. Verma, Nathan Luetke, Steve Branch

Engineering Technology Faculty Publications

The automotive industry has higher-skilled positions available that need engineers and engineering technologists qualified and capable to work in a high-paced, advanced manufacturing sector. Various educational programs across the country offer programs related to the motorsports area at the Associate of Science level. There are also various articu-lation agreements that enable students to continue their education to the baccalaureate level. These programs try to fill in the gap related to the skills shortage in systems and new design methods and processes. The main strength of such educational pathways is that students, who are trained to work as technicians with an …

The Antipatent: A Proposal For Startup Immunity, Amy L. Landers

Nebraska Law Review

I. Introduction

II. The Proposed Solution: The Antipatent

III. Assumptions: Ideas, Inventions, and Innovations

IV. The Value of Experimentation without Adverse Consequences ... A. Clearer Paths to Creation ... B. Components of Creative Endeavors

V. Patent Lock-In: Standing on the Shoulders of Plaintiffs ... A. The Difficult Path to Permission: Search ... B. Patent Lock-In ... C. Patent Law’s Limited Experimental Use Defense ... D. Prior User Rights ... E. Other Private Ordering Solutions ... 1. Patent Pledges ... 2. Coordinated Efforts to Resolve Innovation Roadblocks

VI. The Rationale for Shielding Startups ... A. The Role of Small Firms in …

College Students’ Perceptions Of Individuals With Anorexia Nervosa: Irritation And Admiration, Danielle M. Geerling, Stephen M. Saunders

Psychology Faculty Research and Publications

Background: Stigmatizing attitudes against anorexia nervosa (AN) may act as barriers to treatment.

Aims: Evaluated college students’ perceptions of AN as compared to major depressive disorder (MDD).

Method: One-hundred two female undergraduates read vignettes describing targets with mild or severe MDD or AN, then rated biological, vanity, and self-responsibility attributions; feelings of admiration, sympathy, and anger; and behavioral dispositions toward coercion into treatment, imitation, and social distance.

Results: AN was perceived more negatively than MDD in terms of vanity attributions, self-responsibility attributions, and feelings of anger, but more positively in terms of admiration and imitation.

Conclusions …

Characterization Of Brd4 During Mammalian Post-Meiotic Sperm Development, Jessica M. Bryant, Greg Donahue, Xiaoshi Wang, Mirella Meyer-Ficca, Lacey J. Luense, Angela H. Weller, Marisa S. Bartolomei, Gerd A. Blobel, Ralph G. Meyer, Benjamin A. Garcia, Shelley L. Berger

Animal, Dairy, and Veterinary Science Faculty Publications

During spermiogenesis, the post-meiotic phase of mammalian spermatogenesis, transcription is progressively repressed as nuclei of haploid spermatids are compacted through a dramatic chromatin reorganization involving hyper-acetylation and replacement of most histones with protamines. Although BRDT functions in transcription and histone removal in spermatids, it is unknown whether other BET family proteins play a role. Immunofluorescence of spermatogenic cells revealed BRD4 in a ring around the nuclei of spermatids containing hyper-acetylated histones. The ring lies directly adjacent to the acroplaxome, the cytoskeletal base of the acrosome, previously linked to chromatin reorganization. The BRD4 ring does not form in acrosomal mutant mice. …

A Dynamic Programming Algorithm For Finding The Optimal Placement Of A Secondary Structure Topology In Cryo-Em Data, Abhishek Biswas, Desh Ranjan, Mohammad Zubair, Jing He

Computer Science Faculty Publications

The determination of secondary structure topology is a critical step in deriving the atomic structures from the protein density maps obtained from electron cryomicroscopy technique. This step often relies on matching the secondary structure traces detected from the protein density map to the secondary structure sequence segments predicted from the amino acid sequence. Due to inaccuracies in both sources of information, a pool of possible secondary structure positions needs to be sampled. One way to approach the problem is to first derive a small number of possible topologies using existing matching algorithms, and then find the optimal placement for each …

Deep Convolutional Neural Networks For Annotating Gene Expression Patterns In The Mouse Brain, Tao Zeng, Rongjian Li, Ravi Mukkamala, Jieping Ye, Shuiwang Ji

Computer Science Faculty Publications

Background: Profiling gene expression in brain structures at various spatial and temporal scales is essential to understanding how genes regulate the development of brain structures. The Allen Developing Mouse Brain Atlas provides high-resolution 3-D in situ hybridization (ISH) gene expression patterns in multiple developing stages of the mouse brain. Currently, the ISH images are annotated with anatomical terms manually. In this paper, we propose a computational approach to annotate gene expression pattern images in the mouse brain at various structural levels over the course of development.

Results: We applied deep convolutional neural network that was trained on a large set …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Synthesis, Molecular Docking, And Antitumoral Activity Of Alnustone-Like Compounds Against Estrogen Receptor Alpha-Positive Human Breast Cancer, Kaan Küçükoğlu, Hati̇ce Seçi̇nti̇, Aykut Özgür, Hasan Seçen, Yusuf Tutar

Turkish Journal of Chemistry

Alnustone-like compounds are promising inhibitors for estrogen receptor \alpha (ER-\alpha), which is a novel cancer therapeutic target. Therefore, 10 alnustone-like compounds with substituents at the phenyl rings were synthesized by condensation of 4-phenyl-2-butanones and cinnamaldehydes via in situ enamination. The compounds displayed either protective activity or inhibited cell growth and proliferation of human breast cancer cells. Molecular docking studies indicated that the synthesized compounds interact with ER-\alpha efficiently. In this work, the protective and inhibitive roles of the synthesized compounds were related to their functional groups and to their binding mode of action on ER-\alpha protein. The compounds are potential …

Purification And Characterization Of Nadph-Cytochrome P450 Reductase From Lake Van Fish Liver Microsomes And Investigation Of Some Chemical And Metals' Effects On The Enzyme Activity, Müslüm Kuzu, Mehmet Çi̇ftci̇

Turkish Journal of Chemistry

NADPH-cytochrome P450 reductase was purified from Lake Van fish liver microsomes by primary and secondary DEAE-cellulose column chromatograph with 20.46 \mu M/min/mg enzyme specific activities, 54.4% purification yield, and purification of 38-fold. The purity of the enzyme was established, and its monomer molecular weight was determined by SDS-polyacrylamide gel electrophoresis. SDS-PAGE results showed a single band and the molecular weight of NADPH-cytochrome P450 reductase was 70 kDa. In addition, optimum ionic strength, optimum pH, optimum temperature, and stable pH values were determined for the enzyme in the kinetic studies performed. K_M and V_{max} were determined for NADPH and cytochrome c. …

Synthesis, Properties, And Electrochemistry Of A Photochromic Compound Based On Dithienylethene And Prodot, Melek Pamuk Algi, Ati̇lla Ci̇haner, Fati̇h Algi

Turkish Journal of Chemistry

The synthesis, photochromic features, and electrochemistry of a novel material based on dithienylethene (DTE) and 3,3-didecyl-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine (didecyl-ProDOT) units are described. It is noteworthy that 1,2-bis(5-(3,3-didecyl-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepin-6-yl)-2-methylthiophen-3-yl)cyclopent-1-ene can be efficiently switched between open and closed states by light in both solution and in the solid poly(methyl metacrylate) (PMMA) matrix. It is also found that the emission of this novel compound can be switched on and off upon irradiation.

Synthesis And Properties Of Novel Magnetic Nanoparticles Grafted With Nitropyridine-Substituted Calix[4]Arene Derivative As Cr^{6+} Extractant, Serkan Sayin, Vi̇ldan Doğan

Turkish Journal of Chemistry

A new calix[4]arene derivative, 3, which functionalized at the lower rim with 2-(2-aminoethyl amino)-5-nitropyridine, was synthesized and characterized by a combination of FTIR, ^1H NMR, ^{13}C NMR, and elemental analysis. Then the calix[4]arene 3 was grafted onto [3-(2,3-epoxypropoxy)propyl]trimethoxysilane-modified Fe_3O_4-- nanoparticles (EPPTMS-MN) to produce new calixarene-adorned magnetic nanoparticles (MN-DiNoPy-Calix (4)). The structure of the calixarene-adorned magnetic nanoparticles 4 was determined by a combination of FTIR, TEM, and elemental analysis. Moreover, a study regarding the removal of toxic HCr_2O_7^- anion from aqueous solution was also carried out with the calixarene-adorned magnetic nanoparticles in solid--liquid extraction studies.

Synthesis Of New Oxindole Derivatives Containing Benzothiazole And Thiazolidinone Moieties Using Nano Silica-Bonded 5-N-Propyl-Octahydro-Pyrimido[1,2-A]Azepinium Chloride (Nsb-Dbu) As Catalyst, Robabeh Baharfar, Narges Shariati

Turkish Journal of Chemistry

A facile one-pot synthesis of novel oxindole derivatives bearing benzothiazolylmethyl-2-thioxothiazolidin-4-one was accomplished via one-pot reaction of 5-oxoindolinylidene rhodanine-3-acetic acid derivatives, 2-aminothiophenol, and triphenyl phosphite in the presence of tetrabutylammonium bromide (TBAB) and nano silica-bonded 5-n-propyl-octahydro-pyrimido[1,2-a]azepinium chloride (NSB-DBU) as heterogeneous reusable nanocatalyst. The target compounds were obtained in excellent yields (85%--92%) and short reaction times under fairly mild reaction conditions.

Regiospecific One-Pot, Combinatorial Synthesis Of New Substituted Pyrimido[4,5-C]Pyridazines As Potential Monoamine Oxidase Inhibitors, Mehdi Rimaz, Paria Pourhossein, Behzad Khalili

Turkish Journal of Chemistry

New 3-aryl-6-methylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones and 3-aryl-6-ethyl-7-thioxo-7,8-dihydropyrimido[4,5-c]pyridazin-5(6H)-ones were efficiently synthesized via a regiospecific one-pot reaction of N-methylbarbituric acid and N-ethyl-2-thiobarbituric acid with various arylglyoxal monohydrates in the presence of hydrazine dihydrochloride in ethanol at 50 °C. The target compounds were obtained in high yields and were regioisomerically pure after recrystallization. These new heterocycles may act as potential MAO_{B} inhibitors.

Pfam Catalyzed Enantioselective Diethylzinc Addition To Imines, Özdemi̇r Doğan, Eda Çağli

Turkish Journal of Chemistry

Chiral amines are important starting materials for the synthesis of biologically important compounds. Enantioselective addition of dialkylzinc reagents to imines is a reliable method for the synthesis of these compounds. Different chiral catalysts were developed and used for this method. Phosphorous based PFAM catalysts were tried for the first time in the enantioselective synthesis of amines by reacting diethylzinc with N-sulfonyl imines and N-diphenylphosphinoyl imines. Chiral amines were isolated with moderate to acceptable yields and enantioselectivities.

Synthesis, Characterization, And Metal Extraction Studies Of A New Macrobicyclic Ligand, Hali̇l Zeki̇ Gök, Yaşar Gök, Esra Eker

Turkish Journal of Chemistry

This article describes the synthesis, characterization, and metal ion binding properties of a new macrobicyclic ligand. Solvent extraction experiments were performed in order to determine the extraction behavior of new macrobicyclic ligand towards selected metal cations. Selective extraction of heavy metals and precious metals is highly demanded due to their toxicity and commercial importance. Based on our experimental results, macrobicyclic ligand 3 demonstrated remarkable affinity towards the Ag^+ ion by 96.7% and 96.9% to the dichloromethane and chloroform phases, respectively. The extraction experiments with macrobicyclic ligand 3 for the Ag^+ ion were repeated at different temperatures to calculate thermodynamic parameters. …

Kojic Acid In Organic Synthesis, Maryam Zirak, Bagher Eftekhari-Sis

Turkish Journal of Chemistry

The reactions of kojic acid in organic synthesis are reviewed. The aim of this review is to cover the literature up to the end of 2014, showing the distribution of publications involving kojic acid chemistry in the synthesis of various pyrone containing compounds, pyridine and pyridone heterocycles, and also other organic compounds. First, introductory text about the preparation, biological, and industrial applications, and the chemical properties of kojic acid is given. Then its uses in organic synthesis are presented considering the reaction type.

One-Pot And Solvent-Free Synthesis Of 3-(9-Hydroxy-3-Methoxy-7-Aryl-6,7,9,10-Tetrahydro-5$H$-Benzo[$H$]Thiazolo[2,3-$B$]Quinazolin-9-Yl)-2$H$-Chromen-2-Ones And Their Antibacterial Evaluation, Ravibabu Velpula, Janardhan Banothu, Rajitha Gali, Yakaiah Sargam, Rajitha Bavantula

Turkish Journal of Chemistry

A series of 3-(9-hydroxy-3-methoxy-7-aryl-6,7,9,10-tetrahydro-5$H$-benzo[$h$]thiazolo[2,3-$b$]quinazolin-9-yl)-2$H$-chromen-2-ones (5a-j) were synthesized by one-pot multicomponent reaction of 6-methoxy-1-tetralone, aryl aldehydes, and thiourea followed by cyclization with 3-(2-bromoacetyl)-2$H$-chromen-2-one in the presence of a Bronsted solid acid catalyst, poly(4-vinylpyridinium)hydrogen sulfate [P(4-VPH)HSO$_{4}$] (0.015 g), under solvent-free conditions at 120 $^{\circ}$C. All the synthesized compounds were characterized by spectral studies and screened for their in vitro antibacterial activity against S. aureus and B. thuringiensis (gram positive), and E. coli and K. pneumoniae (gram negative) bacterial strains. On comparing with the standard drug gentamicin, compounds derived from 4-methoxy and 3,4,5-trimethoxy benzaldehyde, i.e. 5g and 5h, showed broad spectrum antibacterial activity …

A New And Simple Procedure For The Trace Determination Of Mercury Using Differential Pulse Polarography And Application To A Salt Lake Sample, Güler Somer, A. Cengi̇z Çalişkan, Olcay Şendi̇l

Turkish Journal of Chemistry

A new and simple differential pulse polarographic procedure was established for the trace determination of mercury(II). An indirect method had to be used since no polarographic peak can be observed for its direct determination. According to their standard potentials, the reaction between SO$_{3}^{2-}$ and Hg(II) was suitable. The peak height of sulfite at about -0.70 V (pH 6, 7) was sharp, high, and very reproducible, enabling the accurate determination of low concentrations of Hg(II). It was found that sulfite concentration had to be 3 times larger than mercury at pH 6, in order to have a quantitative reaction. The procedure …

Dinitrogen Reduction On A Polypyrrole Coated Pt Electrode Under High-Pressure Conditions: Electrochemical Impedance Spectroscopy Studies, Di̇dem Balun Kayan, Fati̇h Köleli̇

Turkish Journal of Chemistry

The electrochemical impedance spectroscopy (EIS) responses of a polypyrrole (PPy)-coated platinum electrode were investigated during N$_{2}$-reduction to ammonia in aqueous medium. Kinetic parameters such as film resistance, pore resistance, and double layer capacitance were analyzed as a function of applied potential and polymer film thickness. The relation between kinetic parameters was discussed by combining electrolysis results. It was found that the optimum film thickness of polypyrrole was 0.73 $\mu $m and optimum potential for ammonia synthesis was -0.150 V under 60 bar N$_{2}$-pressure. The impedance responses under these conditions presented the lowest pore resistance value of ca. 2 $\Omega $ …

Green Synthesis Of 2-Amino-7-Hydroxy-4-Aryl-4$H$-Chromene-3-Carbonitriles Using Zno Nanoparticles Prepared With Mulberry Leaf Extract And Zncl$_{2}$, Akbar Mobinikhaledi, Atisa Yazdanipour, Majid Ghashang

Turkish Journal of Chemistry

A highly efficient and environmentally benign protocol for the synthesis of 2-amino-7-hydroxy-4-aryl-4$H$-chromene-3-carbonitrile derivatives in good to high yields (77%-97%) by one-pot three-component coupling reaction of aromatic aldehydes, malononitrile, and resorcinol under reflux condition was developed in aqueous media using ZnO nanoparticles that were prepared in the presence of mulberry leaf extract under mild conditions.

Acid-Free Synthesis Of S-Nitrosothiols At Neutral Ph By Shock-Freezing In Liquid Nitrogen, Dimitrios Tsikas, Anke Böhmer, Arne Trettin, Arslan Arinç Kayaçelebi̇

Turkish Journal of Chemistry

A laboratory method for the acid-free synthesis of S-nitrosothiols (RSNO) from NaNO$_{2}$ and thiols in aqueous buffer of neutral pH is reported. Equimolar amounts of NaNO$_{2}$ and thiol are added to a 100-$\mu $M Na$_{4}$EDTA-containing Na$_{2}$HPO$_{4}$ buffer (100 mM, pH 7.4). Samples are set into liquid nitrogen for 1 min and then thawed to room temperature or in an ice bath. Dependent upon the RSNO, repetition of the procedure may be required. This method may be of particular importance when the classical acid-based method fails or releases harmful gases such as H$_{2}$S.