Digital Commons Network^™

Climate Change Impacts On The Soil Erosion And Nutrient Losses In The Great Lakes Region, Wang Lili

Open Access Dissertations

Pollutants from non-point sources (NPS) have become the primary reason for water quality degradation in the Great Lakes region after great progress has been made in reducing point source pollution through the enforcement of total maximum daily loads (TMDL). Climate change may impact NPS pollutant transportation processes through influencing runoff

Tick-Flavivirus Interactions: Discovery Of Host Proteins That Are Affected In Virus Infection, Jeffrey Michael Grabowski

Open Access Dissertations

Grabowski, Jeffrey M. Ph.D., Purdue University, August 2015. Tick-Flavivirus Interactions: Discovery of Host Proteins That Are Affected in Virus Infection. Major Professors: Catherine A. Hill and Richard J. Kuhn.

Synthesis, Characterization, In Vitro Evalution, And Preclinical Profiling Of Β-Cyclodextrin Polyrotaxane Families For Use As Potential Niemann-Pick Type C Therapeutics, Christopher James Collins

Open Access Dissertations

Niemann-Pick Disease Type C (NPC) is a rare, autosomal recessive genetic disorder featuring a loss of proteins responsible for unesterified cholesterol (UC) trafficking through the late endosomes/lysosomes (LE/LY) of every cell of the body. Disruption of this pathway leads to abnormal accumulation and storage of UC and other lipids. A broad range of visceral and neurological symptoms result from this accumulation exhibiting a variable age of onset and a disease progression that is ultimately fatal. The disease has an incidence of approximately 1 in 120,000 live births and has no known effective treatment.

Habit Formation In A Rodent Model Of Alcoholism: Genetic Susceptibility, Alcohol-Specific Effects, And Pharmacological Manipulation, David Scott O'Tousa

Open Access Dissertations

Habit formation is a well-characterized process involving a shift from response-outcome as the leading driving force underlying action to a stimulus-response mechanistic process. It is hypothesized that a transition from goal-directed behavior to habitual behavior is driven by a transition of the bulk of cognitive load from neocortical toward lower neurological mechanisms. While many neurotransmitter systems have a demonstrated involvement in this process, the dopamine system is particularly implicated. Habit formation is assessed through the maintenance of extinction responding for an undesired, or devalued, outcome.

Microbial Controls On The Environmental Fate Of Carbon Nanomaterials, Timothy Dale Berry

Open Access Dissertations

Since the synthesis of the first carbon nanomaterials (CNM) 30 years ago, researchers and manufacturers have recognized the potential of these materials to transform the world. The unique physical properties and incredible resilience of these materials gives them countless applications and has led to significant increases in their production over the last decade. However, despite their growing prevalence, the properties and processes controlling the degradation of CNM in the environment remain poorly understood. The primary purpose of this dissertation is to examine the role of environmental microorganisms in degrading CNM and to elucidate which CNM properties and environmental processes represent …

Impacts Of Land-Atmosphere Interactions On Regional Convection And Rainfall, Yue Zheng

Open Access Dissertations

High resolution (1-10 km) numerical weather prediction (NWP) models face major challenges trying to improve representation of moist processes. In particular, simulating the interaction between the land surface and regional convection and rainfall is a source of uncertainties and presents three main barriers: (i) NWP models generally have simple land surface schemes, (ii) land-atmosphere coupling is not properly represented in models, and (iii) many assumptions made in deriving the theory of convective parameterizations are no longer valid at “gray scales” (e.g., 1-10 km). In this dissertation, interactions between land-surface heterogeneities, land-atmosphere coupling, and moist convection and related mesoscale circulations were …

Cultural Considerations In Forensic Science In The United States, Suzanna K. Taylor, Wayne P. Bergeron

Politics, Justice, Law, and Philosophy

Does the cultural context of any criminal justice element, ranging from the crime victim to the forensic science expert, have any impact on the pursuit of justice? Is forensic science completely free of cultural adulteration? Two dimensions of the cultural consideration variable this paper focuses on are (1), what areas of forensic analysis need to be considered to prevent, or at least, diminish cultural offenses in processing crime scenes and forensic evidence, and (2) the need of forensic science professionals and organizations to adopt a consistent scientific culture in processing and analyzing evidence (particularly in DNA analysis). While many empirical …

First Graders As Sensitive Social Partners And Skilled Readers, Zaira R. Arvelo Alicea

Open Access Dissertations

This mixed methods dissertation is guided by a sociocultural framework and a pragmatist stance to contribute to early literacy scholarship about minority children. In particular, I explore the relationship between low socioeconomic status Puerto Rican children’s reading experience and their social cognition by: (1) assessing them through quantitative and qualitative measures that reveal their capacities in these areas at the end of their first grade year, and (2) documenting their reading experiences at home and at school through ethnographic qualitative methods. The analyses revealed significant positive correlations between the tests of reading and social understanding, a scarcity of conventional reading …

Creation And Validation Of The Critical Thinking About Sustainability Scale, Vivian Gregory Alexander

Open Access Dissertations

Alexander, Vivian G. Ph.D., Purdue University, December 2015. Creation and Validation of the Critical Thinking about Sustainability Scale. Major Professor: Yukiko Maeda.

Drug Delivery To Solid Tumors Via Polymeric Nanoparticles, Sara Ahmed

Open Access Dissertations

A main challenge in chemotherapy is to deliver an anti-cancer drug selectively to tumor and avoid off-target exposure to other body tissues and organs. Nanoparticles (NPs) have been considered a promising approach for tumor drug delivery, with popularity attributable to the famous “Enhanced Permeability and Retention effect”, where small particles enter tumor tissues through leaky vasculature and be retained there. Currently, the phagocytic clearance of NPs is avoided by coating NP surface with Polyethylene glycol (PEG). Although successful in prolonging NPs circulation, PEG prevents proper interaction of NPs with the target cells, known as “PEG dilemma”. Low molecular weight chitosan …

Tracking Plant Virus Infections Through Multiple Dimensions: A Search For Sources Of Nonpersistent Virus Vectors And Reservoirs At Local And Regional Scales, Gina Marie Angelella

Open Access Dissertations

My dissertation explores the ecology of aphid-vectored viruses in Midwestern cucurbits; in particular, it focuses on identifying source populations of vectors and virus reservoirs within fields and interactions of vector aphids with land cover surrounding and within fields. Initially, I identified the most commonly occurring viruses and aphid species associated with virus infections in pumpkin fields located across Indiana. This was done by assaying cucurbit leaf tissue with multiplex-rt-PCR targeting all four aphid-vectored, nonpersistent viruses found in cucurbits (papaya ringspot virus type-W, watermelon mosaic virus type-2, zucchini yellow mosaic virus, cucumber mosaic virus) and concurrently monitoring aphid species alightment in …

Relationships Between Behavioral Measures And Productivity In Growing Beef Cattle, Kelsey Bruno

Theses and Dissertations--Animal and Food Sciences

The relationships between behavioral measures, growth performance, and immunocompetence in receiving beef steers were explored in three experiments. Specifically, exit velocity (EV) and objective chute score (OCS) were examined as temperament measures. In experiment 1, no main effects or interactions with degradable intake protein (DIP) or interactions between temperament measures were observed (P ≥ 0.11); however, high OCS steers had greater intake and gain:feed (P < 0.10) and slow EV steers had higher intake and gain (P < 0.10) than their counterparts. In experiment 2, during week two of social observations, dominance hierarchy rankings were dependent on OCS and EV (P < 0.05); slow EV steers also had increased antibody responses and gain (P < 0.10) and high OCS steers had increased gain (P < 0.10). In experiment 3, subjective chute scores and OCS were positively correlated (P < 0.01) and both EV and OCS treatments changed over time (P < 0.10); intake, vaccine titer response, and gain:feed responses to monensin were dependent on OCS treatment (P < 0.10). The studies suggest that temperament, measured by EV and OCS, affects growth performance and health related measures and is related to social dominance behavior in receiving beef steers.

An Evaluation Of Precision Dairy Farming Technology Adoption, Perception, Effectiveness, And Use, Matthew Richard Borchers

Theses and Dissertations--Animal and Food Sciences

Precision dairy farming technologies provide a variety of functions to dairy farmers. Little is known about dairy producer perception of these technologies. A study was performed to understand dairy producer perception of parameters monitored by precision dairy farming technologies. Calving has potential to be predicted using these same parameters and technologies. A second study was performed using two commercially marketed technologies in calving prediction. In order for these technologies to generate accurate and useful information for dairy farm use, they must accurately quantify these parameters. The final study evaluated the accuracy of five commercially marketed technologies in monitoring feeding, rumination, …

Assessing The Efficacy Of Automated Detection Of Estrus In Dairy Cattle, Lauren M. Mayo

Theses and Dissertations--Animal and Food Sciences

The detection of estrus continues to be a primary factor contributing to poor reproductive performance in modern dairy cattle. The objectives of this research were 1) to evaluate performance of automated detection of estrus using a reference standard of ovulation detection with temporal progesterone patterns 2) to evaluate the efficacy of parameters measured by automated detection of estrus systems 3) to evaluate the efficacy of alerts generated by several commercially available systems used for automated detection of estrus and 4) to determine the differences in these parameters among cows with or without poor health conditions at the time of estrus. …

Using The Indicator Amino Acid Oxidation Technique To Study Threonine Requirements In Horses Fed Different Feed Compositions, Chanhee Mok

Theses and Dissertations--Animal and Food Sciences

Threonine has been reported to be the second limiting amino acid in typical equine diets, but its actual requirement has not been determined in horses. The indicator amino acid oxidation (IAAO) method has been successfully used for evaluating amino acid metabolism and requirements in animals and humans. The objective of this research was to use the IAAO method to estimate threonine requirements in mature horses fed two different feed compositions. In the first study, 6 Thoroughbred mares (4 – 16 years old) received each of 6 levels of threonine intake in a high concentrate diet, in a randomly determined order. …

Vol. 40, No. 4: Holiday 2015, School Of Medicine & Health Sciences

North Dakota Medicine Archive

No abstract provided.

Our Pathway To God: Scent, T Ryan

Theology Papers and Journal Articles

No abstract provided.

Egads! Preservation Run Amok: A Call For Change To Arkansas's Was It Raised?, Was It Developed?, Was It Ruled On? Jurisprudence, Brian G. Brooks

University of Arkansas at Little Rock Law Review

No abstract provided.

Law, Bioethics, And Medical Futility: Defining Patient Rights At The End Of Life, Frederick R. Parker Jr.

University of Arkansas at Little Rock Law Review

No abstract provided.

Color And Texture Morphing With Colloids On Multilayered Surfaces, Ziguang Chen, Shumin Li, Andrew Arkebauer, George Gogos, Li Tan

Department of Mechanical and Materials Engineering: Faculty Publications

Dynamic morphing of marine species to match with environment changes in color and texture is an advanced means for surviving, self-defense, and reproduction. Here we use colloids that are placed inside a multilayered structure to demonstrate color and texture morphing. The multilayer is composed of a thermal insulating base layer, a light absorbing mid layer, and a liquid top layer. When external light of moderate intensity (∼0.2 W cm−2) strikes the structure, colloids inside the liquid layer will be assembled to locations with an optimal absorption. When this system is exposed to continuous laser pulses, more than 18 000 times …

Mammalian Synthetic Biology: Emerging Medical Applications, Zoltan Kis, Hugo Sant'ann Pereira, Takayuki Homma, Ryan M. Pedrigi, Rob Krams

Department of Mechanical and Materials Engineering: Faculty Publications

In this review, we discuss new emerging medical applications of the rapidly evolving field of mammalian synthetic biology.We start with simple mammalian synthetic biological components and move towards more complex and therapy-oriented gene circuits. A comprehensive list of ON–OFF switches, categorized into transcriptional, post-transcriptional, translational and posttranslational, is presented in the first sections. Subsequently, Boolean logic gates, synthetic mammalian oscillators and toggle switches will be described. Several synthetic gene networks are further reviewed in the medical applications section, including cancer therapy gene circuits, immuno-regulatory networks, among others. The final sections focus on the applicability of synthetic gene networks to drug …

Effective Teaching In Higher Education For The 21st Century Adult Learner, Denise Murchison Payton

Walden Dissertations and Doctoral Studies

Abstract

As college populations are becoming increasingly diverse, institutions must find ways to meet the needs of their nontraditional students. Nontraditional adult learners are self-directed, ready to learn, and are internally motivated to engage in problem-centered learning. The purpose of this study was to expand and refine an active learning seminar in a higher education setting to improve the quality of teaching, student engagement, and retention rates. The site of the study was a Historically Black College and University (HBCU) in which adult students over 25 constituted 49% of the population. The faculty members at this site predominantly employed traditional …

Self-Efficacy, Locus Of Control, And Parental Involvement On Students' Academic Achievement, Helen Faye Clay-Spotser

Walden Dissertations and Doctoral Studies

Minority students are lagging behind their non-minority peers in academic achievement. Compounding this problem is the lack of research on minority students' perceptions on their connections to school, their feelings of autonomy, and their relationship with their parents. These variables are important considerations in this problem, as Ryan and Deci's self-determination theory suggests a strong relationship between student performance in school and students' perceptions of their intrinsic and extrinsic motivators. To address that gap, this cross-sectional, quantitative research study examined the relationship between minority high school students' perceived self-efficacy, locus of control, and parents' educational involvement on their self-reported academic …

Personality Traits Associated With Environmental Concern, Tara Rae Wuertz

Walden Dissertations and Doctoral Studies

The 5 factor model of personality, including the traits of openness, conscientiousness, extraversion, agreeableness, and neuroticism, is a well-established theoretical model for describing how personality is structured. Hirsh (2010) demonstrated the big 5 personality traits, excluding extraversion, were correlated with pro-environmental attitudes. The purpose of this quantitative study was to replicate previous findings, and discover if there was a correlation with a person's pro-environmental behaviors and the big 5 personality traits. A total of 100 participants from an online participant pool completed a survey, which included the Environmental Concern Scale to measure concern and attitudes about the environment, and the …

Learned Helplessness And Depression: Comparison Of Skilled Nursing And Assisted Living Facilities, Paul Lynn Susic

Walden Dissertations and Doctoral Studies

Research with geriatric populations suggests high levels of clinical depression and greater financial and psychological costs of treatment in long-term care facilities with more restrictive care. Research on learned helplessness, a construct separate from depression, suggests learned helplessness and perceived control are useful theories for the study of elder depression, but the relationship between depression and learned helplessness in this population is not clear. This cross-sectional quantitative study examined the relationship between depression and learned helplessness by comparing residents over age 65 in less restrictive assisted living (n =42) versus those in more restrictive skilled nursing facilities (n =63). Data …

A Mindfulness-Based Stress Reduction Psychoeducational Program In Postpartum Support Groups, Marina Pesserl

Walden Dissertations and Doctoral Studies

Postpartum Depression (PPD) affects 15% of women after childbirth. Its etiology includes psychoneuroimmunologic factors with long-lasting postpartum stressors that lead to allostatic overload. Using mindfulness-based stress reduction (MBSR) for PPD has not yet been studied. Addressing this literature gap, the potential benefits of including an 8-week MBSR component based on Beck's theory of PPD at support groups were examined in this phenomenological study based on a sample of 10 women and 2 group facilitators. Purposes of the study included describing the experience of PPD and the MBSR program, identifying the stage of behavioral change of the participants, and describing the …

Centering The Teenage "Siren": Adolescent Workers, Sexual Harassment, And The Legal Construction Of Race And Gender, Anastasia M. Boles

Law Faculty Scholarship

Recent scholarship and media attention has focused on the prevalence of sexually harassing behavior directed at working teenagers, and the emergence of sexual harassment lawsuits by these minors against their employers. Although many of the legal issues concerning workplace sexual harassment and adult workers (and the various state and federal jurisprudence prohibiting it) have been widely discussed, there is surprisingly little discourse, research, and precedent addressing the problem of workplace sexual harassment and teen workers.

Currently, most sexual harassment cases brought by adolescent workers are litigated using the doctrinal framework for adult workers. Only the Seventh Circuit has developed an …

Mcm2 And Chromogranin Are Markers Of Serrated Polyp Progression, Danielle Fortuna, Md, Bruce M. Boman, Md, Phd, Juan P. Palazzo, Md

Department of Pathology, Anatomy, and Cell Biology Resident's Posters

Objectives:

Using immunohistochemistry for MCMs and CGA:

Examine the proliferative compartment of SPs

Assess neuroendocrine cell population in SPs

Goal: Identify potential trends in the proliferative and the neuroendocrine cell compartments in SP progression compared to the background normal mucosa

Twenty Years: Reflections And Questions, Alice Brand

The Journal of the Assembly for Expanded Perspectives on Learning

Recalling her lifelong research into the connection between emotions and writing, the first editor of JAEPL critiques scholarly contexts that limit the exploration of knowledge about writing.

Linking Classroom Learning And Research To Advance Ideas About Social-Ecological Resilience, Natalie C. Ban, Emily Boyd, Michael Cox, Chanda L. Meek, Michael Schoon, Sergio Villamayor-Tomas

Dartmouth Scholarship

There is an increasing demand in higher education institutions for training in complex environmental problems. Such training requires a careful mix of conventional methods and innovative solutions, a task not always easy to accomplish. In this paper we review literature on this theme, highlight relevant advances in the pedagogical literature, and report on some examples resulting from our recent efforts to teach complex environmental issues. The examples range from full credit courses in sustainable development and research methods to project-based and in-class activity units. A consensus from the literature is that lectures are not sufficient to fully engage students in …