Digital Commons Network^™

Traits And Roles Of Jonas Kamlet, Pioneering Chemistry Consultant, As A Guide To Contemporary Inventors, Dean F. Martin, Autumn S. Thompson

Chemistry Faculty Publications

As state universities feel economic pinches of reduced support from state legislatures, and as sources of federal funding for supported research projects face additional challenges, other sources of support need to be found. Two sources under consideration are royalties and licensing fees for successful patents. A good example of a successful developer of patents was Jonas Kamlet, Ph.D. (1914‐1960), who was an early consultant in chemical and other matters and was the successful co-owner, with his wife Edna, of the Kamlet Laboratories. The roles that he played in his career can, we believe, provide good examples for contemporary researchers in …

An Atlantis Ecosystem Model For The Gulf Of Mexico Supporting Integrated Ecosystem Assessment, Cameron Ainsworth, Michael Schirripa, Hem Nalini Morzaria-Luna

C-IMAGE Publications

"The Gulf of Mexico supports a high biological diversity and biomass of fish, seabirds, and mammals; in this region, multiple commercial and recreational fishing fleets operate providing economic resources for local populations. The Gulf is also the site of important oil and gas production and tourism. As a result of intensive human use, the Gulf is subject to various impacts, including oil spills, habitat degradation, and anoxia. Management of this Large Marine Ecosystem requires an ecosystem-based management approach that provides a holistic approach to resource management. The Gulf of Mexico is managed as part of NOAA's Integrated Ecosystem Assessment Program …

Lethal And Sublethal Effects Of Oil, Chemical Dispersant, And Dispersed Oil On The Ctenophore Mnemiopsis Leidyi, Ryan F. Peiffer, Jonathan H. Cohen

C-IMAGE Publications

We established the lethal levels for water-accommodated fractions of Corexit^® 9500A chemical dispersant, crude oil (WAF), and dispersed crude oil (CEWAF) for the ctenophore Mnemiopsis leidyi at both 15 and 23°C. This gelatinous zooplankter was sensitive to dispersant at both temperatures, as well as to oil solutions, with some increase in toxicity of CEWAF as compared to WAF. Subsequent sublethal assays for routine respiration rate, bioluminescence, and glutathione-s-transferase (GST) activity were conducted on individuals surviving 24 h exposures to test solutions at both 15 and 23°C. GST activity increased significantly in 2.5 and 5 mg l^-1 dispersant solutions …

Basic Epidemiology, Center For Leadership In Public Health Practice

Preparedness and Emergency Response Learning Center

Basic Epidemiology, a training course from the USF Center for Leadership in Public Health Practice, develops the awareness and knowledge of public health workers who may be deployed on Field Epidemiology strike teams. It is designed to help them assist local, regional, state, and national epidemiology staff in disease investigations during surge capacity. Basic Epidemiology is a required prerequisite for the IFIRST and IFIRST-2 programs.

Rectifying These Mean Streets: Percent-For-Art Ordinances, Street Furniture, And The New Streetscape, Asmara M. Tekle

Kentucky Law Journal

No abstract provided.

Summary Of The Kentucky River Watershed Watch 2015 Water Sampling Results, Kentucky Water Resources Research Institute

Kentucky River Watershed Watch

No abstract provided.

Internet Reviews: Open Access Institutional Repositories, Jennifer A. Bartlett

Library Faculty and Staff Publications

No abstract provided.

Previous Preterm Birth And Current Maternal Complications As A Risk Factor Of Subsequent Stillbirth, Boubakari Ibrahimou, Cynthia Anozie, Cara De La Cruz, Hamisu Salihu

Epidemiology and Biostatistics Faculty Publications

Purpose. To examine the association between previous preterm birth and the risk of stillbirth. Methods. This population-based retrospective cohort study analyzed live births and stillbirth records in Missouri (1989–1997). The main outcome of interest was stillbirth occurrence while the exposures were prior preterm birth. Adjusted odds ratios and 95% confidence intervals were computed using logistic regression. Results. Women who had a previous preterm birth have 63% increased odds of stillbirth in singleton pregnancies and 75% increased odds in twins as compared to those who did not have a preterm birth in a prior pregnancy (AOR = 1.63, 95% CI = …

Clinical Significance Of Cd44s, Cd44v3 And Cd44v6 In Breast Cancer, Xiao-Jin Wu, Xiao-Dong Li, Hanze Zhang, Xiaofei Zhang, Zhong-Hua Ning, Yong-Mei Yin, Ye Tian

Epidemiology and Biostatistics Faculty Publications

Objectives: To evaluate levels of CD44 standard variant (CD44s), CD44 variant exon 3 (CD44v3) and CD44 variant exon 6 (CD44v6) protein in breast cancer tissue, and investigate their relationships with clinicopathological characteristics of the disease.

Methods: Immunohistochemistry for CD44s, CD44v3 and CD44v6 was retrospectively performed on formalin-fixed paraffin wax-embedded breast cancer tissue samples.

Results: Tumour tissue samples from 60 patients with breast cancer were included. There was a significant relationship between CD44s positivity and tumour diameter and lymph node involvement. CD44v6 positivity was significantly associated with tumour–node–metastasis (TNM) stage and lymph node involvement. There were significant negative correlations between CD44s …

The Time For Design-Based Research Is Right And Right Now, Jennifer K. Shah, David C. Ensminger, Kimberly Their

Mid-Western Educational Researcher

The science-to-service problem continues to taunt the field of education (Fixsen, Blasé, Naoom, & Wallace, 2009). As an academic discipline, the field requires knowledge generation that adds to or deepens theoretical understandings. As a profession, knowledge generation that solves local problems and supports continuous improvement is necessary. Using design-based research (DBR) provides a means of serving theoretical and practical needs in education, addressing the complexity of education by informing immediate practice while simultaneously contributing to theoretical understandings in the field of education. Using Stokes’ (1977) model of scientific research and knowledge generation, we situate DBR within Pasteur’s quadrant, describe how …

Self-Reported Race/Ethnicity In The Age Of Genomic Research: Its Potential Impact On Understanding Health Disparities, Tesfaye B. Mersha, Tilahun Abebe

Faculty Work

This review explores the limitations of self-reported race, ethnicity, and genetic ancestry in biomedical research. Various terminologies are used to classify human differences in genomic research including race, ethnicity, and ancestry. Although race and ethnicity are related, race refers to a person’s physical appearance, such as skin color and eye color. Ethnicity, on the other hand, refers to communality in cultural heritage, language, social practice, traditions, and geopolitical factors. Genetic ancestry inferred using ancestry informative markers (AIMs) is based on genetic/genomic data. Phenotype-based race/ethnicity information and data computed using AIMs often disagree. For example, self-reporting African Americans can have drastically …

Gender Variation In Acoustic Characteristics Of Southern Pa-O Lexical Tones, Sujinat Jitwiriyanont

Manusya, Journal of Humanities

Southern Pa-O (S. Pa-O) is a Karenic language of the Tibeto-Burman subgroup of the Sino-Tibetan language family. In Thailand, there is a large S. Pa-O community around Rama II Road. This study aims to investigate the gender variation in acoustic characteristics of S. Pa-O lexical tones. F0 in Hertz based on the biological difference of larynx vibrating rate was converted into semitones to normalize cross-speaker differences. Then, semitone and real time values of 6 lexical tones (4 non-checked tones and 2 checked tones) were used to generate 2nd degree polynomial trendlines to show F0 contours and shapes. The results reveal …

Women Of Faith In Science: The Double Glass Ceiling, K. Y. Michael

Journal of Mathematics and Science: Collaborative Explorations

The majority of female pre-service elementary school teachers pursuing licensure is choosing English as their cognate rather than mathematics or science. The reason females are not choosing science as their cognate may be due to the fact that science has long been considered a masculine pursuit. To complicate the issue, pre-service female teachers of deep religious faith are further challenged to navigate the dichotomy of science and religion. As a result, women, and especially women of deep religious faith, are at risk of not participating in science studies. The author suggests that there is room in the science classroom for …

Stemteach: Preparing The Next Generation Of Mathematics And Science Teachers, G. Bunn, D. Dailey, A. Cotabish

Journal of Mathematics and Science: Collaborative Explorations

With an increasing demand for individuals prepared in Science, Technology, Engineering, and Mathematics (STEM), one university responded to this call by changing its teacher preparation program. Better-prepared mathematics and science teachers have the opportunity to engage and excite students, thereby preparing and promoting more of them to enter the STEM professions. The described program is a replication of the national UTeach model that recruits content majors in mathematics and science to explore the teaching profession during a first-semester course that includes an early field experience in the elementary grades. This field experience is designed to be engaging for both the …

A Review Of The Sunshine Act's Open Payments Program: Are Patients Still In The Dark?, Shirley Chen

Loyola Consumer Law Review

No abstract provided.

Michigan Academician, Volume 42, Issue 2

Michigan Academician

No abstract provided.

Michigan Academician, Volume 42, Issue 3

Michigan Academician

No abstract provided.

Grand Valley Magazine, Vol. 14, No. 3 Winter 2015, Grand Valley State University

Grand Valley Magazine

Grand Valley Magazine is a quarterly publication about Grand Valley State University produced by University Communications since 2001.

2015 Projects Day Booklet, Seattle University

Projects Day Booklets

No abstract provided.

"If They Hand You A Paper, You Sign It": A Call To End The Sterilization Of Women In Prison, Rachel Roth, Sara L. Ainsworth

UC Law SF Journal on Gender and Justice

A 2013 investigative report on California prisons exposed the recent use of coercive tactics to induce women in prison in that state to undergo sterilization surgeries to permanently end their fertility. This is particularly striking given California's infamous history as the state that forcibly sterilized the largest number of people during the eugenics era. But California is not the only state that permits, condones, and may use public money to sterilize women in prison. This article begins with a consideration of the history of eugenic sterilization, and its troubling revival against the very women-women of color and poor women- who …

Infants In Orange: An International Model-Based Approach Prison Nurseries, Jennifer Warner

UC Law SF Journal on Gender and Justice

Prison nurseries are used throughout the world as a way to strengthen the initial mother-child bond and ensure that mothers are given a chance to raise their children, even if it's behind bars. Ms. Warner outlines the differences between prison nurseries in countries like Germany, Colombia, and Kenya, and reveals that the United States is vastly different from the rest. While most countries offer prison nurseries, only nine states within the United States utilize a prison nursery, which means the majority of United States jails and prisons routinely separate newborns from their incarcerated mothers. Ms. Warner urges her readers and …

Forbidden Fruit: Sexual Victimization Of Migrant Workers In America's Farmlands, Christa Conry

UC Law SF Journal on Gender and Justice

There is a place in the booming agricultural fields of America's farmlands that carries a terrible history. The fields de calzons, or fields of panties, are where female farmworkers, mostly migrant employees residing in the United States for the harvest, are systematically violated by foremen, colleagues, and other superiors. There are 1.4 million crop workers in the United States. Twenty-four percent of these workers are estimated to be female. A recent report suggests that as many as eighty percent of female farmworkers surveyed are regularly exposed to sexual harassment, assault, and trauma, ranging from continuous sexual advances over years …

Antiproliferative And Antiestrogenic Activities Of Bonediol An Alkyl Catechol From Bonellia Macrocarpa, Rosa Moo-Puc, Edgar Caamal-Fuentes, Sergio R. Peraza-Sánchez, Anna Slusarz, Glenn Jackson, Sara K. Drenkhahn, Dennis B. Lubahn

Faculty Scholarship

The purpose of this study was to investigate antiproliferative activity of bonediol, an alkyl catechol isolated from the Mayan medicinal plant Bonellia macrocarpa. Bonediol was assessed for growth inhibition of androgen-sensitive (LNCaP), androgen-insensitive (PC-3), and metastatic androgen-insensitive (PC-3M) human prostate tumor cells; toxicity on normal cell line (HEK 293) was also evaluated. Hedgehog pathway was evaluated and competitive 3H-estradiol ligand binding assay was performed. Additionally, antioxidant activity on Nrf2-ARE pathway was evaluated. Bonediol induced a growth inhibition on prostate cancer cell lines (IC50 from 8.5 to 20.6 µM). Interestingly, bonediol binds to both estrogen receptors (ERα (2.5 …

Effects Of A Dietary Supplement On Golf Drive Distance And Functional Indices Of Golf Performance, Tim N. Ziegenfuss, Scott M. Habowski, Robert Lemieux, Jennifer E. Sandrock, A. William Kedia, Chad M. Kerksick, Hector L. Lopez

Faculty Scholarship

Background

Limited research exists examining the impact of nutrition on golfing performance. This study’s purpose was to determine the impact of daily supplementation with an over-the-counter dietary supplement on golf performance.

Methods

Healthy men (30.3 ± 6.9 y, 183.1 ± 5.6 cm, 86.7 ± 11.9 kg), with a 5–15 handicap were assigned in a double-blind, placebo-controlled manner to ingest for 30 days either a placebo (PLA, n = 13) or a dietary supplement containing creatine monohydrate, coffea arabica fruit extract, calcium fructoborate and vitamin D (Strong Drive™, SD, n = 14). Subjects ingested two daily doses for the first two …

Localisation Of 11Β-Hydroxysteroid Dehydrogenase Type 2 In Mineralocorticoid Receptor Expressing Magnocellular Neurosecretory Neurones Of The Rat Supraoptic And Paraventricular Nuclei, M. Haque, R. Wilson, K. Sharma, N. J. Mills, R. Teruyama

Faculty Publications

© 2015 British Society for Neuroendocrinology. An accumulating body of evidence suggests that the activity of the mineralocorticoid, aldosterone, in the brain via the mineralocorticoid receptor (MR) plays an important role in the regulation of blood pressure. MR was recently found in vasopressin and oxytocin synthesising magnocellular neurosecretory cells (MNCs) in both the paraventricular (PVN) and supraoptic (SON) nuclei in the hypothalamus. Considering the physiological effects of these hormones, MR in these neurones may be an important site mediating the action of aldosterone in blood pressure regulation within the brain. However, aldosterone activation of MR in the hypothalamus remains controversial …

Metabolic And Photosynthetic Consequences Of Blocking Starch Biosynthesis In The Green Alga Chlamydomonas Reinhardtii Sta6 Mutant, Anagha Krishnan, G. Kenchappa Kumaraswamy, David J. Vinyard, Huiya Gu, Gennady Ananyev, Matthew C. Posewitz, G. Charles Dismukes

Faculty Publications

© 2015 The Authors The Plant Journal © 2015 John Wiley & Sons Ltd. Upon nutrient deprivation, microalgae partition photosynthate into starch and lipids at the expense of protein synthesis and growth. We investigated the role of starch biosynthesis with respect to photosynthetic growth and carbon partitioning in the Chlamydomonas reinhardtii starchless mutant, sta6, which lacks ADP-glucose pyrophosphorylase. This mutant is unable to convert glucose-1-phosphate to ADP-glucose, the precursor of starch biosynthesis. During nutrient-replete culturing, sta6 does not re-direct metabolism to make more proteins or lipids, and accumulates 20% less biomass. The underlying molecular basis for the decreased biomass phenotype …

Increased Phosphate Transport Of Arabidopsis Thalianapht1;1 By Site-Directed Mutagenesis Of Tyrosine 312 May Be Attributed To The Disruption Of Homomeric Interactions, Elena B. Fontenot, Sandra Feuer Ditusa, Naohiro Kato, Danielle M. Olivier, Renee Dale, Wei Yi Lin, Tzyy Jen Chiou, Megan A. Macnaughtan, Aaron P. Smith

Faculty Publications

& Sons Ltd. Members of the Pht1 family of plant phosphate (Pi) transporters play vital roles in Pi acquisition from soil and in plantaPi translocation to maintain optimal growth and development. The study of the specificities and biochemical properties of Pht1 transporters will contribute to improving the current understanding of plant phosphorus homeostasis and use-efficiency. In this study, we show through split in vivo interaction methods and in vitro analysis of microsomal root tissues that Arabidopsis thalianaPht1;1 and Pht1;4 form homomeric and heteromeric complexes. Transient and heterologous expression of the Pht1;1 variants, Pht1;1^Y312D, Pht1;1^Y312A and Pht1;1^{Y312F …}

Il-1Β Reciprocally Regulates Chemokine And Insulin Secretion In Pancreatic Β-Cells Via Nf-Κb, Susan J. Burke, Krisztian Stadler, Danhong Lu, Evanna Gleason, Anna Han, Dallas R. Donohoe, Richard C. Rogers, Gerlinda E. Hermann, Michael D. Karlstad, J. Jason Collier

Faculty Publications

© 2015 the American Physiological Society. Proinflammatory cytokines impact islet β-cell mass and function by altering the transcriptional activity within pancreatic β-cells, producing increases in intracellular nitric oxide abundance and the synthesis and secretion of immunomodulatory proteins such as chemokines. Herein, we report that IL-1β, a major mediator of inflammatory responses associated with diabetes development, coordinately and reciprocally regulates chemokine and insulin secretion. We discovered that NF-κB controls the increase in chemokine transcription and secretion as well as the decrease in both insulin secretion and proliferation in response to IL-1β. Nitric oxide production, which is markedly elevated in pancreatic β-cells …

Respiratory Syncytial Virus Disease Is Mediated By Age-Variable Il-33, Jordy Saravia, Dahui You, Bishwas Shrestha, Sridhar Jaligama, David Siefker, Greg I. Lee, Jeffrey N. Harding, Tamekia L. Jones, Cynthia Rovnaghi, Bindiya Bagga, John P. Devincenzo, Stephania A. Cormier

Faculty Publications

© 2015 Saravia et al. Respiratory syncytial virus (RSV) is the most common cause of infant hospitalizations and severe RSV infections are a significant risk factor for childhood asthma. The pathogenic mechanisms responsible for RSV induced immunopathophysiology remain elusive. Using an age-appropriate mouse model of RSV, we show that IL-33 plays a critical role in the immunopathogenesis of severe RSV, which is associated with higher group 2 innate lymphoid cells (ILC2s) specifically in neonates. Infection with RSV induced rapid IL-33 expression and an increase in ILC2 numbers in the lungs of neonatal mice; this was not observed in adult mice. …

Mechanistic Species Distribution Modelling As A Link Between Physiology And Conservation, Tyler G. Evans, Sarah E. Diamond, Morgan W. Kelly

Faculty Publications

© The Author 2015. Climate change conservation planning relies heavily on correlative species distribution models that estimate future areas of occupancy based on environmental conditions encountered in present-day ranges. The approach benefits from rapid assessment of vulnerability over a large number of organisms, but can have poor predictive power when transposed to novel environments and reveals little in the way of causal mechanisms that define changes in species distribution or abundance. Having conservation planning rely largely on this single approach also increases the risk of policy failure. Mechanistic models that are parameterized with physiological information are expected to be more …