Digital Commons Network^™

Fluorescent Biological Aerosol Particles In Coastal Canada And The Link To Atmospheric Ice Nuclei, Jixiao Li

Electronic Theses and Dissertations

Bioaerosols are a subgroup of atmospheric aerosols and are often linked to the spread of human, animal and plant diseases. Bioaerosols also may play an indirect effect on environmental processes, including the formation of precipitation and alteration of the global climate through their role as nuclei for cloud droplet formation. Several types of biological organisms (e.g., fungi and bacteria) have been shown to be effective ice nuclei (IN) and cloud condensation nuclei (CCN).

During 21 days in August 2013 we participated in a collaborative international campaign at a rural, coastal site near the village of Ucluelet on the west coast …

Graduate Scholar 2015: Journal Of Scholarship And Recognition, Graduate School Of Eastern Illinois University

Graduate Scholar

No abstract provided.

Effects Of Degradation On Mechanical Properties Of Tissue-Engineering Poly(Glycolic Acid) Scaffolds, Yushane Celestine Shih

Yale Medicine Thesis Digital Library

Tissue-engineered vascular grafts (TEVGs) offer tremendous therapeutic potential for congenital cardiovascular malformations, and our computational model of growth and remodeling may help expedite TEVG design by identifying optimal scaffold parameters. To evaluate our model’s assumptions about scaffold physical properties, we measured the effects of in vitro hydrolytic degradation on the compressibility and mechanical behavior of poly(glycolic acid) (PGA) scaffolds. Degradation in neutral PBS at 37°C passed through two stages of first-order decay: the first 50 percent of PGA mass was lost from 5 to 40 days (~1 to 6 weeks) at a rate constant of 0.175/wk, after which the mass …

Correlations Between Sensory Encoding And Central Morphology Of Muscle Proprioceptors In The Rat, Hanna Marie Gabriel

Browse all Theses and Dissertations

Until now, observations regarding the central morphology and organization of Ia, group II and Ib Golgi tendon organ afferents have been confined to the cat model. As the use of rodents in the study of the development and organization of segmental spinal cord circuitry increases, a complete account of the peripheral encoding and central connectivity of rodent muscle proprioceptors is necessary. The data presented in this study establish the central morphology and spatial distribution of 12 (4 of each class) functionally phenotyped muscle proprioceptor afferents in the rat by intracellular labeling with Neurobiotin. Each afferent type showed a characteristic central …

Characterization Of Dimethyl Sulfoxide-Treated Wool And Enhancement Of Reactive Wool Dyeing In Non-Aqueous Medium, Luyi Chen, Bijia Wang, Jiangang Chen, Xinhui Ruan, Yiqi Yang

Department of Textiles, Merchandising and Fashion Design: Faculty Publications

Wool pretreated with dimethyl sulfoxide (DMSO) was characterized and its dyeing behavior in non-aqueous green solvents was investigated. Reactive dyeing of wool in deep shades is challenging because the mandatory alkaline aftertreatment to match the fastness of mordant dyes inevitably causes damage to wool keratin. The current study showed that the colorfastness-integrity dilemma could be solved by replacing water with organic solvents as the dyeing medium. Covalent fixation is predominantly favored in solvent dyeing so that excellent colorfastness is achievable at any given shade without alkali aftertreatment. Compared with aqueous dyeing, solvent dyeing was found to give 30% higher covalent …

Histone Deacetylase Inhibitory Activity Of Hydroxycapsaicin, A Synthetic Derivative Of Capsaicin, And Its Cytotoxic Effects Against Human Colon Cancer Cell Lines, Thanaset Senawong, Paweena Wongphakham, Thussanee Saiwichai, Chanokbhorn Phaosiri, Pakit Kumboonma

Turkish Journal of Biology

Capsaicin possesses cytotoxic/anticancer activity and shares some common structural features, including a benzene ring and a long hydrophobic carbon tail, with the histone deacetylase (HDAC) inhibitors trichostatin A and suberoylanilide hydroxamic acid. The aims of this study were to investigate HDAC inhibitory and cytotoxic activities of a synthetic derivative of capsaicin, hydroxycapsaicin (6-hydroxy-N-(4-hydroxy-3-methoxybenzyl)-8-methylnonenamide), in colon cancer cell lines. Hydroxycapsaicin inhibited HDAC activity in vitro (IC50 = 72 µM) much more effectively than the prototype capsaicin (IC50 > 13.1 mM) and also exhibited HDAC inhibitory activity in human cells (HeLa cells). MTT assay demonstrated that hydroxycapsaicin was less toxic than capsaicin against …

Eugenol Biologic Activity In Immunosuppressed Rat Females With Candida Albicans Genital Infection: Histocytological Changes, Romeo Teodor Cristina, Diana Obistioiu, Eugenia Dumitrescu, Ileana Nichita, Florin Muselin, Diana Brezovan, Mihai Sorin Cernea

Turkish Journal of Biology

From our prior studies concerning eugenol's biologic activity we observed the very good in vitro antifungal efficiency of this natural compound. Those positive results generated the need to supplement the available information with a comparative in vivo animal model. In this context, our current study was proposed to ascertain and compare the effects of eugenol with nystatin with a placebo control group (saline solution) by evaluating the cytohistological alterations in immunosuppressed Wistar female rats genitally infected with Candida albicans. The observed histological alterations were most apparent in the placebo group. Candidiasis affected the liver, ovaries, kidneys, and spleen of the …

Investigation Of The In Vivo Interaction Between Ss-Lactamase And Its Inhibitor Protein, Ni̇lay Büdeyri̇ Gökgöz, Si̇may Yalaz, Naze Gül Avci, Gi̇zem Buldum, Eli̇f Özkirimli Ölmez, Berna Sariyar Akbulut

Turkish Journal of Biology

The affinity of ß-lactamase inhibitory protein (BLIP) for TEM-1 ß-lactamase has raised hopes in the challenge of protein-based inhibitor discovery for ß-lactamase-mediated antibiotic resistance. Currently, the effect of the formation of the ß-lactamase:BLIP complex in vivo in ß-lactam resistant bacteria is an open question. The scarcity of information to the extent to which BLIP can impair ß-lactamase activity inside cells has urged us to assess the in vivo efficacy of BLIP as a potent ß-lactamase inhibitor. To this end, ß-lactamase and BLIP were coexpressed in Escherichia coli. Simultaneous expression of ß-lactamase and BLIP and the formation of the TEM-1 ß-lactamase:BLIP …

Development And Application Of Pseudoreceptor Modeling, Gregory Lee Wilson

Open Access Dissertations

Quantitative Structure-Activity Relationship (QSAR) methods are a commonly used tool in the drug discovery process. These methods attempt to form a statistical model that relates descriptor properties of a ligand to the activity of that ligand compound towards a specific desired physiological response. QSAR methods are known as a ligand-based method, as they specifically use information from ligands and not protein structural data. However, a derivation of QSAR methods are pseudoreceptor methods. Pseudoreceptor methods go beyond standard QSAR by building a model representation of the protein pocket. However, the ability of pseudoreceptors to accurately replicate natural protein surfaces has not …

Anticancer Effects Of Vitamin E Forms And Their Long-Chain Metabolites Via Modulation Of Sphingolipid Metabolism, Yumi Jang

Open Access Dissertations

Cancer is one of the leading causes of death. Studies have shown that vitamin E forms including gamma-tocopherol (γT), delta-tocopherol (δT), and gamma-tocotrienol (γTE) exhibited potent anticancer activities in various types of cancer cells. But molecular mechanisms underlying anticancer actions of γTE are not completely understood. 13’-carboxychromanols (13’-COOHs), major fecal excreted long-chain metabolites of vitamin E, have recently been shown to induce apoptosis in liver cancer cells. However, it is not clear whether 13’-COOHs have anticancer effects on other types of cancer. In the current study, we investigated the anticancer effects and mechanisms of γTE and 13’-COOHs; δT-13’-COOH and δTE-13’-COOH, …

Modeling Of Interface Strength As Well As Interface Deformation Based On Nanomechanics And Development Of Interface Database Systems, Tao Qu

Open Access Dissertations

Biomaterials such as bone and marine exoskeletons have primarily an organic phase (e.g. tropocollagen in bone, chitin in exoskeleton) and an inorganic phase (e.g. hydroxyapatite in bone, calcite in exoskeleton) arranged in a precisely organized multi-level hierarchical arrangement. Interfacial interactions between the organic and inorganic phases significantly affect the mechanical properties of such biomaterials. In presented study, idealized tropocollagen-hydroxyapatite and chitin-calcite interfacial systems are analyzed using a multiscale simulation framework that combines explicit three-dimensional molecular dynamics simulations with finite element simulations that take into account explicit microstructure in a three-dimensional hierarchy. The analyses focus on the shear deformation that occurs …

From Temperament To Character, Andrew Mullins

Philosophy Conference Papers

No abstract is available for this paper.

Santa Clara Magazine, Volume 56 Number 2, Winter 2015, Santa Clara University

Santa Clara Magazine

10 - May the Rhodes rise to meet you - On the road with Aven Satre-Meloy ’13.

16 - Season tough, photos by Denis Concordel.

18 - Space Aces by Sam Scott '96. 20 - The fragility of faith by Michael C. McCarthy, S.J. '87. A professor of religious studies and executive director of SCU’s Ignatian Center for Jesuit Education confesses that it’s not merely an academic question when he asks: “How can a thinking person still believe in God?”

26 - Rebound by Mitch Finley '73. Lessons from the court and the chapel in dealing with addiction, mental illness, …

Fostering Students' Identification With Mathematics And Science, Brett D. Jones, Chloe Ruff, Jason W. Osborne

Education Faculty Publications

Book Summary: Interest in Mathematics and Science Learning is the first volume to assemble findings on the role of interest in mathematics and science learning. As the contributors illuminate across the volume’s 22 chapters, interest provides a critical bridge between cognition and affect in learning and development. This volume will be useful to educators, researchers, and policy makers, especially those whose focus is mathematics, science, and technology education.

Chapter Summary: The primary purpose of this chapter is to explore the process whereby students transition from a short-term, situational interest in mathematics or science to a more enduring individual interest in …

Mexican-Origin Parents’ Work Conditions And Adolescents’ Adjustment, Lorey A. Wheeler, Kimberly A. Updegraff, Ann Crouter

Nebraska Center for Research on Children, Youth, Families, and Schools: Faculty Publications

Mexican-origin parents’ work experiences are a distal extra-familial context for adolescents’ adjustment. This two-wave multi-informant study examined the prospective mechanisms linking parents’ work conditions (i.e., self-direction, work pressure, workplace discrimination) to adolescents’ adjustment (i.e., educational expectations, depressive symptoms, risky behavior) across the transition to high school drawing on work socialization and spillover models. We examined the indirect effects of parental work conditions on adolescent adjustment through parents’ psychological functioning (i.e., depressive symptoms, role overload) and aspects of the parent-adolescent relationship (i.e., parental solicitation, parent-adolescent conflict), as well as moderation by adolescent gender. Participants were 246 predominantly immigrant, Mexican-origin, two-parent families …

Dynamic Environmentalism & Adaptive Management: Legal Obstacles And Opportunities, Jonathan H. Adler

Faculty Publications

Most of today’s environmental laws and programs are based upon outmoded assumptions about the relative stability of natural systems when free of human interference. Scientists have understood for decades that ecosystems are anything but stable. To the contrary, ecosystems are incredibly dynamic and change over time due to both internal and external forces. Accounting for dynamic nature may require revisiting conventional notions of environmental protection and the underpinnings of environmental law and management. This presents an enormous challenge. Conventional approaches to environmental management may be unable to heed dynamic environmentalism’s call so long as they are confined by contemporary notions …

Species Preference Of Viral Deubiquitinating Proteases Toward Isg15 Through Structural And Enzymatic Characterization, Michelle Kay Deaton

Electronic Theses and Dissertations

Proteases from the Ovarian Tumor domain (OTU) superfamily of deubiquitinating enzymes (DUBs) are expressed by a range of RNA viruses. Viral OTUs (vOTUs) are found in nairoviruses such as Crimean Congo Hemorrhagic Fever virus (CCHFV), Nairobi sheep disease virus (NSDV), the Erve virus (ERVEV), and the Dugbe virus (DUGV), as well as in the areterivirus Porcine Reproductive and Respiratory Syndrome virus (PRRSV), among others. vOTUs, which interfere with host innate immune response through editing of host Ub and Ub-like molecules such as interferon stimulated gene 15 (ISG15), have been identified as a potential virulence factor through their role in evading …

Risk For Engagement In Nonsuicidal Self-Injury In Children And Adolescents, Andrea Lee Barrocas Gottlieb

Electronic Theses and Dissertations

Although NSSI engagement is a growing public health concern, little research has documented the developmental precursors to NSSI in longitudinal studies using youth samples. This study aimed to expand upon previous research on groups of NSSI engagement in a population-based sample of youth using multi-wave data. Moreover, this study examined whether chronic peer and romantic stress, the serotonin transporter gene (5-HTTLPR), parenting behaviors, and negative attributional style predicted the NSSI group membership as well as the role of sex and grade. Participants were 549 youth in beginning in the 3^rd, 6^th, and 9^th grades at …

Finding Onesimus: Recovering The Story Of A First-Century Fugitive Slave, Ryan Lokkesmoe

Electronic Theses and Dissertations

This dissertation is an investigation into the experience of a first-century fugitive slave named Onesimus, who is known to us primarily through Paul’s letter to Philemon (Phlm) in the New Testament. Within this broader purpose, this project challenges a popular historical theory for Onesimus’ flight, the so-called Amicus Domini theory. This is the theory that Onesimus fled his master Philemon with the premeditated intention of seeking out the Apostle Paul as a peacemaker in a conflict Onesimus was having with Philemon. The Amicus Domini theory is accepted by many scholars, though rarely discussed in detail or examined critically.

The goal …

A Mixed Methods Evaluation Of The Effectiveness Of A Group Yoga Intervention As An Adjunctive Trauma Therapy For Adolescent Girls, Melissa Eileen Houser

Electronic Theses and Dissertations

Neuroscience findings support the need for trauma treatments that work from the lowest levels of the brain up to the highest levels of the brain (Perry, 2009) due to evidence that the inverse relationship between amygdala and medial prefrontal cortex is not as strong in individuals who have experienced trauma, leading to difficulty in inhibiting fear responses through cognition (McRae, Ochsner, & Gross 2011). Difficulties associating language with traumatic events have also been found (van der Kolk, 2006). The integration of mindfulness practices and the popularization of yoga in the West have led to use of yoga to address trauma …

Ada Foundation Names Dr. Thomas C. Hart Director Of The Adaf Dr. Anthony Volpe Research Center, American Dental Association

News Releases

This collection includes standard news releases, information kits and other documents distributed for publicity, information, announcements of events, etc. as issued from the ADA. Items included in this collection are archival and any costs, links, contact information, or other figures may be out of date. Please contact the ADA to verify information.

Modern Capitalism And Food Commoditization: The Limitations Of Industrial Agriculture And The Challenges Of Sustainable Alternatives, Gerardo Patron-Cano

Electronic Theses and Dissertations

Agriculture is an essential function of contemporary human life that is bound by nature. Therefore, economic, social, and environmental perspectives must be examined to identify the most sustainable agricultural systems. This thesis argues that agriculture should be divorced from capitalist economic principles regarding specialization, trade, and production scale. Such principles have supported industrialized growing methods, which have been economically, socially, and environmentally unsustainable. In order for agriculture to be sustainable and equitable, food systems need to be de-commoditized and removed from the capitalist market. Policies should target the local control of food systems by empowering communities to subsidize localized production-consumption …

Sustainable Development And Its Discontents, Federico Cheever, John C. Dernbach

Sturm College of Law: Faculty Scholarship

Sustainable development (or sustainability) is a decision-making framework for maintaining and achieving human well-being, both in the present and into the future. The framework requires both consideration and achievement of environmental protection, social justice and economic development. In that framework, environmental protection must be integrated into decisions about social and economic development, and social justice and economic viability must be integrated into decisions about environmental quality.

First endorsed by the world’s nations in 1992, this framework is intended to provide an effective response to the twin global challenges of growing environmental degradation and widespread extreme poverty. Sustainability provides a framework …

"Teaching" Formation Of Professional Identity, David I.C. Thomson

Sturm College of Law: Faculty Scholarship

This Article is my attempt to provide a guide to what professional identity formation is—as distinct from more familiar concepts of professionalism and ethics—and what legal educators are doing, and could do in the future, to foster this sort of professional formation in their courses and curricula. In Part I, I offer some background and history of the topic, which supports a new definition provided in the Article for lawyer professional identity formation. I describe in Part II what some schools are doing to “teach” formation of professional identity and argue that those efforts have some significant limitations. I argue …

2015-2016 Student Handbook, Nova Southeastern University

NSU Student Handbooks

No abstract provided.

Preparatory Optometry Program 2014-2015, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Open Educational Resources Presentation For Librarians With Notes, Tucker T. Taylor, Amie Freeman

A repository of copyright educational resources for higher education

This presentation is created for faculty. students or librarians. It contains an overview of Open Educational Resources and Open Textbooks, and also describes several projects including MERLOT and Openstax. Descriptive notes are included in the slides to assist future presenters.

Effects Of Light And Water Availability On The Performance Of Hemlock Woolly Adelgid (Hemiptera: Adelgidae), Mauri Hickin, Evan L. Preisser

Biological Sciences Faculty Publications

Eastern hemlock (Tsuga canadensis (L.) Carriere) is a dominant shade-tolerant tree in northeastern United States that has been declining since the arrival of the hemlock woolly adelgid (Adelges tsugae Annand). Determining where A. tsugae settles under different abiotic conditions is important in understanding the insect’s expansion. Resource availability such as light and water can affect herbivore selectivity and damage. We examined how A. tsugae settlement and survival were affected by differences in light intensity and water availability, and how adelgid affected tree performance growing in these different abiotic treatments. In a greenhouse at the University of Rhode Island, …

Going Global: The Introduction Of The Asian Isopod Ianiropsis Serricaudis Gurjanova (Crustacea: Peracarida) To North America And Europe, Niels-Viggo Hobbs, Eric Lazo-Wasem, Marco Faasse, Jeffrey R. Cordell, John W. Chapman, Carter S. Smith, Robert Prezant, Rebecca Shell, James T. Carlton

Biological Sciences Faculty Publications

The Asian isopod Ianiropsis serricaudis is now well established in fouling communities, often associated with introduced ascidians, throughout the Northern Hemisphere but has gone largely unnoticed because of its diminutive size (typically less than 3 mm in length) and the difficulties of identifying small peracarid crustaceans. Known locations include the northeastern Pacific (Puget Sound, San Francisco Bay, and Monterey Bay), the northwestern Atlantic (from the Gulf of Maine to Barnegat Bay, NJ), and the northeastern Atlantic (England and the Netherlands). We predict that this species is widespread along North America and European coasts, and may already be introduced to cold …

Debating The Role Of Higher Education In Society, Bryan Dewsbury

Biological Sciences Faculty Publications

Review of: Beyond the University: In Defense of Liberal Education, Michael S. Roth; (2014). Yale University Press, New Haven, CT. 228 pages.