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2015

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A Proteinuria Cut-Off Level Of 0.7 G/Day After 12 Months Of Treatment Best Predicts Long-Term Renal Outcome In Lupus Nephritis: Data From The Maintain Nephritis Trial, F. Tamirou, B. R. Lauwerys, M. Dall'era, M. Mackay, B. Rovin, R. Cervera, F. A. Houssiau, D. Abramowicz, L. De Bruxelles, R. Westhovens, +35 Additional Authors Jan 2015

A Proteinuria Cut-Off Level Of 0.7 G/Day After 12 Months Of Treatment Best Predicts Long-Term Renal Outcome In Lupus Nephritis: Data From The Maintain Nephritis Trial, F. Tamirou, B. R. Lauwerys, M. Dall'era, M. Mackay, B. Rovin, R. Cervera, F. A. Houssiau, D. Abramowicz, L. De Bruxelles, R. Westhovens, +35 Additional Authors

Journal Articles

BACKGROUND: Although an early decrease in proteinuria has been correlated with good long-term renal outcome in lupus nephritis (LN), studies aimed at defining a cut-off proteinuria value are missing, except a recent analysis performed on patients randomised in the Euro-Lupus Nephritis Trial, demonstrating that a target value of 0.8 g/day at month 12 optimised sensitivity and specificity for the prediction of good renal outcome. The objective of the current work is to validate this target in another LN study, namely the MAINTAIN Nephritis Trial (MNT). METHODS: Long-term (at least 7 years) renal function data were available for 90 patients randomised …

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Sustaining The Rheumatology Research Enterprise, A. Davidson, D. Polsky Jan 2015

Sustaining The Rheumatology Research Enterprise, A. Davidson, D. Polsky

Journal Articles

No abstract provided.

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Tyk2 Protein-Coding Variants Protect Against Rheumatoid Arthritis And Autoimmunity, With No Evidence Of Major Pleiotropic Effects On Non-Autoimmune Complex Traits, D. Diogo, L. Bastarache, K. P. Liao, R. R. Graham, R. S. Fulton, J. D. Greenberg, S. Eyre, A. Lee, P. K. Gregersen, R. M. Plenge, +44 Additional Authors Jan 2015

Tyk2 Protein-Coding Variants Protect Against Rheumatoid Arthritis And Autoimmunity, With No Evidence Of Major Pleiotropic Effects On Non-Autoimmune Complex Traits, D. Diogo, L. Bastarache, K. P. Liao, R. R. Graham, R. S. Fulton, J. D. Greenberg, S. Eyre, A. Lee, P. K. Gregersen, R. M. Plenge, +44 Additional Authors

Journal Articles

Despite the success of genome-wide association studies (GWAS) in detecting a large number of loci for complex phenotypes such as rheumatoid arthritis (RA) susceptibility, the lack of information on the causal genes leaves important challenges to interpret GWAS results in the context of the disease biology. Here, we genetically fine-map the RA risk locus at 19p13 to define causal variants, and explore the pleiotropic effects of these same variants in other complex traits. First, we combined Immunochip dense genotyping (n = 23,092 case/control samples), Exomechip genotyping (n = 18,409 case/control samples) and targeted exon-sequencing (n = 2,236 case/controls samples) to …

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Widespread Non-Additive And Interaction Effects Within Hla Loci Modulate The Risk Of Autoimmune Diseases, T. Lencz, A. J. Deutsch, B. Han, X. Hu, Y. Okada, S. Eyre, M. Knapp, A. Zhernakova, P. K. Gregersen, S. Raychaudhuri, +27 Additional Authors Jan 2015

Widespread Non-Additive And Interaction Effects Within Hla Loci Modulate The Risk Of Autoimmune Diseases, T. Lencz, A. J. Deutsch, B. Han, X. Hu, Y. Okada, S. Eyre, M. Knapp, A. Zhernakova, P. K. Gregersen, S. Raychaudhuri, +27 Additional Authors

Journal Articles

Human leukocyte antigen (HLA) genes confer substantial risk for autoimmune diseases on a log-additive scale. Here we speculated that differences in autoantigen-binding repertoires between a heterozygote's two expressed HLA variants might result in additional non-additive risk effects. We tested the non-additive disease contributions of classical HLA alleles in patients and matched controls for five common autoimmune diseases: rheumatoid arthritis (ncases = 5,337), type 1 diabetes (T1D; ncases = 5,567), psoriasis vulgaris (ncases = 3,089), idiopathic achalasia (ncases = 727) and celiac disease (ncases = 11,115). In four of the five diseases, we observed highly significant, non-additive dominance effects (rheumatoid arthritis, …

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Pioglitazone In Early Parkinson's Disease: A Phase 2, Multicentre, Double-Blind, Randomised Trial, T. Simuni, K. Kieburtz, B. Tilley, J. J. Elm, B. Ravina, D. Babcock, M. Emborg, Andrew Feigin, R. Zweig, Parkinson Ninds Exploratory Trials, +38 Additinal Authoris Jan 2015

Pioglitazone In Early Parkinson's Disease: A Phase 2, Multicentre, Double-Blind, Randomised Trial, T. Simuni, K. Kieburtz, B. Tilley, J. J. Elm, B. Ravina, D. Babcock, M. Emborg, Andrew Feigin, R. Zweig, Parkinson Ninds Exploratory Trials, +38 Additinal Authoris

Journal Articles

Background A systematic assessment of potential disease-modifying compounds for Parkinson's disease concluded that pioglitazone could hold promise for the treatment of patients with this disease. We assessed the effect of pioglitazone on the progression of Parkinson's disease in a multicentre, double-blind, placebo-controlled, futility clinical trial. Methods Participants with the diagnosis of early Parkinson's disease on a stable regimen of 1 mg/day rasagiline or 10 mg/day selegiline were randomly assigned (1:1:1) to 15 mg/day pioglitazone, 45 mg/day pioglitazone, or placebo. Investigators were masked to the treatment assignment. Only the statistical centre and the central pharmacy knew the treatment name associated with …

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Nontraditional Students In Management And Accounting Programs: Investigating The Relationship Between Personality And Major Satisfaction In The Community College Setting, Brad Ward Jan 2015

Nontraditional Students In Management And Accounting Programs: Investigating The Relationship Between Personality And Major Satisfaction In The Community College Setting, Brad Ward

Doctor of Business Administration (DBA)

High school students and working-age adults are frequently pressured by teachers, relatives, peers, employers, and state and federal governments to attend college for such reasons as obtaining new skills, increasing salary and prestige, and seeking new career opportunities (Baxter & Kavanagh, 2012; Calmes, 2014; Holcomb, 2008; Pringle, DuBose, & Yankey, 2010). Approximately 25% of these students drop out of school within the freshman year (ACT, 2013) due, in part, to a poor personality fit with their major (Jones & Jones, 2014). Consequently, attrition has become a costly problem for university administrators and taxpayers (American Institutes for Research, 2011). Personality is …

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Bachelor Of Science Psychology 2015-2016 Curriculum, Nova Southeastern University Jan 2015

Bachelor Of Science Psychology 2015-2016 Curriculum, Nova Southeastern University

CPS Undergraduate Course Catalogs

No abstract provided.

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Why Video Game Genres Fail: A Classificatory Analysis, Rachel I. Clarke, Jin Ha Lee, Neils Clark Jan 2015

Why Video Game Genres Fail: A Classificatory Analysis, Rachel I. Clarke, Jin Ha Lee, Neils Clark

School of Information Studies - Faculty Scholarship

This paper explores the current affordances and limitations of video game genre from a library and information science perspective with an emphasis on classification theory. We identify and discuss various purposes of genre relating to video games, including identity, collocation and retrieval, commercial marketing, and educational instruction. Through the use of examples, we discuss the ways in which these purposes are supported by genre classification and conceptualization, and the implications for video games. Suggestions for improved conceptualizations such as family resemblances, prototype theory, faceted classification, and appeal factors for video game genres are considered, with discussions of strengths and weaknesses. …

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Solvent Effects In The Extraction And Detection Of Polycyclic Aromatic Hydrocarbons From Complex Oils In Complex Environments, Nicole Serio, Mindy Levine Jan 2015

Solvent Effects In The Extraction And Detection Of Polycyclic Aromatic Hydrocarbons From Complex Oils In Complex Environments, Nicole Serio, Mindy Levine

Chemistry Faculty Publications

Anthropogenic oil spills such as the 2010 Deepwater Horizon oil spill present a number of unique challenges in environmental remediation, detection, and monitoring of a wide range of toxicants in complex environments. We have previously reported the use of cyclodextrin derivatives to accomplish the selective extraction of polycyclic aromatic hydrocarbons (PAHs) and facilitate their detection via proximity-induced energy transfer. Reported herein is the ability of these cyclodextrins to operate in a real-world scenario: extracting PAHs from oil collected from an oil spill site and from tar ball extracts into crude seawater from the Narragansett Bay in Rhode Island. The ability …

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Behavioral Neuroscience, Nova Southeastern University Jan 2015

Behavioral Neuroscience, Nova Southeastern University

CPS Undergraduate Course Catalogs

No abstract provided.

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Degree Curriculum Sheet | 2015 Catalog Bachelor Of Science - Secondary Mathematics Education, Nova Southeastern University Jan 2015

Degree Curriculum Sheet | 2015 Catalog Bachelor Of Science - Secondary Mathematics Education, Nova Southeastern University

Abraham S. Fischler College of Education and School of Criminal Justice Undergraduate Course Catalogs

No abstract provided.

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Memorabilia 2015, Kean University Jan 2015

Memorabilia 2015, Kean University

Memorabilia Yearbooks

Yearbook of Kean University

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Purifying And Analyzing Spider Silk Proteins For Commercial Use, Emily Thomas Jan 2015

Purifying And Analyzing Spider Silk Proteins For Commercial Use, Emily Thomas

Biology Posters

No abstract provided.

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Survey Of Plant Diseases And Pests In Utah Raspberries, Sean Christensen Jan 2015

Survey Of Plant Diseases And Pests In Utah Raspberries, Sean Christensen

Biology Posters

No abstract provided.

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Mapping The Landscape Of Children’S Play., David F. Lancy Jan 2015

Mapping The Landscape Of Children’S Play., David F. Lancy

Sociology, Social Work and Anthropology Faculty Publications

No abstract provided.

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Cultural Views Of Life Phases., David F. Lancy, M. Annette Grove Jan 2015

Cultural Views Of Life Phases., David F. Lancy, M. Annette Grove

Sociology, Social Work and Anthropology Faculty Publications

The knowledge base in the study of human development is built primarily from work with children from the modern, global, post-industrial population. This population is unrepresentative in many respects, not least in that childhood and adolescence is dominated by the experience of formal schooling—an experience missing from the lives of most of the world’s children until very recently. This entry will examine child development from the perspective of pre-modern societies as described in the ethnographic, archaeological and historic records. Specifically, we will review material indicative of cultural or indigenous models of development, phases and phase transitions, in particular.

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Playing With Knives: The Socialization Of Self-Initiated Learners, David F. Lancy Jan 2015

Playing With Knives: The Socialization Of Self-Initiated Learners, David F. Lancy

Sociology, Social Work and Anthropology Faculty Publications

Since Margaret Mead's field studies in the South Pacific a century ago, there has been the tacit understanding that as culture varies, so too must the socialization of children to become competent culture users and bearers. More recently, the work of anthropologists has been mined to find broader patterns that may be common to childhood across a range of societies. One improbable commonality has been the tolerance, even encouragement, of toddler behavior that is patently risky, such as playing with or attempting to use a sharp-edged tool. This laissez faire approach to socialization follows from a reliance on children as …

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Ada News Convention Daily - 2015 Day 2, American Dental Association, Publishing Division Jan 2015

Ada News Convention Daily - 2015 Day 2, American Dental Association, Publishing Division

ADA News

The ADA News Daily (also called the ADA News Convention Daily) is a special edition of the ADA News published each day during American Dental Association Annual Sessions.

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Tackling Cancer By Drug Design, Krista Olsen Jan 2015

Tackling Cancer By Drug Design, Krista Olsen

Biology Posters

No abstract provided.

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Validation Of Rapid And Cheap Field Assessment In Gartersnakes, Landon Fehlberg Jan 2015

Validation Of Rapid And Cheap Field Assessment In Gartersnakes, Landon Fehlberg

Biology Posters

No abstract provided.

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Oral Surgery Internship, Taylor Nielsen Jan 2015

Oral Surgery Internship, Taylor Nielsen

Biology Posters

No abstract provided.

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Comparing Structures Of Two Antimicrobial Peptides Using A Self-Organized Mapping Approach, Faramarz Joodaki, Preston Steele, Lenore M. Martin, Michael L. Greenfield Jan 2015

Comparing Structures Of Two Antimicrobial Peptides Using A Self-Organized Mapping Approach, Faramarz Joodaki, Preston Steele, Lenore M. Martin, Michael L. Greenfield

Cell and Molecular Biology Faculty Publications

No abstract provided.

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Aquilegia, Vol. 39 No. 1, Spring 2015, Newsletter Of The Colorado Native Plant Society, Jan Loechell Turner Jan 2015

Aquilegia, Vol. 39 No. 1, Spring 2015, Newsletter Of The Colorado Native Plant Society, Jan Loechell Turner

Aquilegia - Colorado Native Plant Society

No abstract provided.

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Aquilegia, Vol. 39 No. 3, Summer 2015: Newsletter Of The Colorado Native Plant Society, Feb Loechell Turner, Charlie Turner Jan 2015

Aquilegia, Vol. 39 No. 3, Summer 2015: Newsletter Of The Colorado Native Plant Society, Feb Loechell Turner, Charlie Turner

Aquilegia - Colorado Native Plant Society

The Colorado Native Plant Society Newsletter will be published on a bimonthly basis. The contents will consist primarily of a calendar of events, notes of interest, editorials, listings of new members and conservation news. Until there is a Society journal, the Newsletter will include short articles also. The deadline for the Newsletter is one month prior to its release.

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Aquilegia, Vol. 39 No. 4, Fall 2015: Newsletter Of The Colorado Native Plant Society, Mar Loechell Turner, Charlie Turner Jan 2015

Aquilegia, Vol. 39 No. 4, Fall 2015: Newsletter Of The Colorado Native Plant Society, Mar Loechell Turner, Charlie Turner

Aquilegia - Colorado Native Plant Society

The Colorado Native Plant Society Newsletter will be published on a bimonthly basis. The contents will consist primarily of a calendar of events, notes of interest, editorials, listings of new members and conservation news. Until there is a Society journal, the Newsletter will include short articles also. The deadline for the Newsletter is one month prior to its release.

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Timing Of Spring Surveys For Midcontinent Sandhill Cranes, Aaron T. Pearse, Gary L. Krapu, David A. Brandt, Glen A. Sargeant Jan 2015

Timing Of Spring Surveys For Midcontinent Sandhill Cranes, Aaron T. Pearse, Gary L. Krapu, David A. Brandt, Glen A. Sargeant

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

The U.S. Fish and Wildlife Service has used spring aerial surveys to estimate numbers of migrating sandhill cranes (Grus canadensis) staging in the Platte River Valley of Nebraska, USA. Resulting estimates index the abundance of the midcontinent sandhill crane population and inform harvest management decisions. However, annual changes in the index have exceeded biologically plausible changes in population size (>50% of surveys between 1982 and 2013 indicate >20% change), raising questions about nuisance variation due to factors such as migration chronology. We used locations of cranes marked with very-highfrequency transmitters to estimate migration chronology (i.e., proportions of …

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White-Tailed Deer (Odocoileus Virginianus) Fawn Risk From Gray Wolf (Canis Lupus) Predation During Summer, L. David Mech, Aaron Morris, Shannon M. Barber-Meyer Jan 2015

White-Tailed Deer (Odocoileus Virginianus) Fawn Risk From Gray Wolf (Canis Lupus) Predation During Summer, L. David Mech, Aaron Morris, Shannon M. Barber-Meyer

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Little is known about how often various prey animals are at risk of predation by Gray Wolves (Canis lupus). We used a system to monitor the presence during the day of two radio-collared Gray Wolves within 2 km of a radio-collared White-tailed Deer (Odocoileus virginianus) with a fawn or fawns in August 2013 in the Superior National Forest of northeastern Minnesota. We concluded that the fawn or fawns were at risk of predation by at least one wolf at least daily.

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Effects Of Drought On Forests And Rangelands In The United States: A Comprehensive Science Synthesis, James M. Vose, James S. Clark, Charles H. Luce, Toral Patel-Weynand Jan 2015

Effects Of Drought On Forests And Rangelands In The United States: A Comprehensive Science Synthesis, James M. Vose, James S. Clark, Charles H. Luce, Toral Patel-Weynand

United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications

This assessment provides input to the reauthorized National Integrated Drought Information System (NIDIS) and the National Climate Assessment (NCA), and it establishes the scientific foundation needed to manage for drought resilience and adaptation. Focal areas include drought characterization; drought impacts on forest processes and disturbances such as insect outbreaks and wildfire; and consequences on forest and rangeland values. Drought can be a severe natural disaster with substantial social and economic consequences. Drought becomes most obvious when large-scale changes are observed; however, even moderate drought can have long-lasting impacts on the structure and function of forests and rangelands without these obvious …

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Not Your Mother's Will: Gender, Language, And Wills, Karen J. Sneddon Jan 2015

Not Your Mother's Will: Gender, Language, And Wills, Karen J. Sneddon

Articles

“Boys will be boys, but girls must be young ladies” is an echoing patriarchal refrain from the past. Formal equality has not produced equality in all areas, as demonstrated by the continuing wage gap. Gender bias lingers and can be identified in language. This Article focuses on Wills, one of the oldest forms of legal documents, to explore the intersection of gender and language. With conceptual antecedents in pre-history, written Wills found in Ancient Egyptian tombs embody the core characteristics of modern Wills. The past endows the drafting and implementation of Wills with a wealth of traditions and experiences. The …

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Contents, Anon Jan 2015

Contents, Anon

Washington Journal of Environmental Law & Policy

No abstract provided.

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