Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2015

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 7771 - 7800 of 8124

Full-Text Articles in Entire DC Network

The Behavior Of Glaucous-Winged Gull Egg Cannibals, Ashley A. Reichert Jan 2015

The Behavior Of Glaucous-Winged Gull Egg Cannibals, Ashley A. Reichert

Honors Theses

Cannibalism leads to a variety of behavioral, demographic, and ecological consequences and is influenced by a range of environmental circumstances among numerous taxa. Although multiple studies have linked cannibalism to egg and chick failure in gull populations, few characterizations of gull cannibal behavior and reproductive success exist. During the 2014 breeding season, we observed the territories of 16 Glaucous-winged Gull (Larus glaucescens) and Glaucous-winged x Western Gull (L. glaucescens x occidentalis) egg cannibal specialists on Protection Island, Washington, USA. We also monitored cannibal foraging behavior, relative reproductive success, and colony-wide egg loss. Cannibal specialists employed a variety of foraging and …


Major Dietary Patterns And Risk Of Acute Myocardial Infarction In Young, Urban Pakistani Population, Romaina Iqbal, Saleem Perwaiz Iqbal, Mohsin Yakub, Asal Khan Tareen, Mohammad Perwaiz Iqbal Jan 2015

Major Dietary Patterns And Risk Of Acute Myocardial Infarction In Young, Urban Pakistani Population, Romaina Iqbal, Saleem Perwaiz Iqbal, Mohsin Yakub, Asal Khan Tareen, Mohammad Perwaiz Iqbal

Community Health Sciences

Objective: To investigate the role of dietary intake in the development of premature acute myocardial infarction (AMI) in a hospital-based Pakistani population in Karachi.
Methods: In a case control study, 203 consecutive patients (146 males and 57 females) with their first AMI and age below 45 years were enrolled with informed consent. Similarly, 205 gender and age matched (within 3 years) healthy adults were also included as controls. Dietary intake of both cases and controls was assessed by using a simple 14-item food frequency questionnaire. Using factor analysis, 3 major dietary patterns- prudent dietary pattern, combination dietary pattern and western …


A Strategy To Improve Nutrition And Increase Physical Activity In Primary School Children., Lisa Delaney Jan 2015

A Strategy To Improve Nutrition And Increase Physical Activity In Primary School Children., Lisa Delaney

Theses

Introduction: Paediatric obesity has become a global epidemic with many countries developing strategies to help tackle its prevalence. School based physical activity (PA) and nutrition interventions have proven to play a promising role in tackling childhood obesity.

Background: Project Spraoi is an Irish primary school based intervention. The intervention was delivered to an intervention school to help enhance PA and nutritional behaviour amongst pupils. The intervention school was assigned an 'Energizer'; a trained PA and nutrition change agent who worked with the school to achieve the objectives. For evaluation purposes a control school was recruited.

Methodology: Pupils from the intervention …


Gmos, Nate Bohm-Levine Jan 2015

Gmos, Nate Bohm-Levine

The Synapse: Intercollegiate science magazine

No abstract provided.


Against The Grain, Dayna Gallagher, Jenn Feigin Jan 2015

Against The Grain, Dayna Gallagher, Jenn Feigin

The Synapse: Intercollegiate science magazine

No abstract provided.


Keep Out Fda: Food Manufacturers' Ability To Effectively Self-Regulate Front-Of-Package Food Labeling, Ellen A. Black Jan 2015

Keep Out Fda: Food Manufacturers' Ability To Effectively Self-Regulate Front-Of-Package Food Labeling, Ellen A. Black

Law Faculty Scholarship

The headlines on any given day claim that the American "obesity epidemic" continues to worsen.' According to these headlines, Americans, both adults and children, are increasingly becoming more obese, are more likely to be diagnosed with diabetes, and will likely prematurely die due to this preventable disease. Numerous private industries, as well as the government, seek to rescue Americans from this crisis. As the obesity epidemic debate intensifies, the call for more government regulation correspondingly grows. There are critics, however, who question the legitimacy of this epidemic and the need for more regulation. For example, some well-known scholars opine that …


Catalog 2015-2016, University Of North Florida Jan 2015

Catalog 2015-2016, University Of North Florida

UNF Course Catalogs

No abstract provided.


Optimising Motor Learning In Infants At High Risk Of Cerebral Palsy: A Pilot Study, Catherine Morgan, Iona Novak, Russell Dale, Nadia Badawi Jan 2015

Optimising Motor Learning In Infants At High Risk Of Cerebral Palsy: A Pilot Study, Catherine Morgan, Iona Novak, Russell Dale, Nadia Badawi

Medical Papers and Journal Articles

Background: The average age for the diagnosis of cerebral palsy (CP) is 19 months. Recent neuroplasticity literature suggests that intensive, task-specific intervention ought to commence as early as possible and in an enriched environment, during the critical period of neural development. Active motor interventions are effective in some populations, however the effects of active motor interventions on the motor outcomes of infants with CP have not been researched thoroughly, but pilot work is promising. The aim of this study was to determine the short- term effects of “GAME”; a new and novel goal-oriented activity-based, environmental enrichment therapy programme on the …


Improving Allied Health Professionals' Research Implementation Behaviours For Children With Cerebral Palsy: Protocol For A Before-After Study, Christine Imms, Iona Novak, Claire Kerr, Nora Shields, Melinda Randall, Adrienne Harvey, H Kerr Graham, Dinah Reddihough Jan 2015

Improving Allied Health Professionals' Research Implementation Behaviours For Children With Cerebral Palsy: Protocol For A Before-After Study, Christine Imms, Iona Novak, Claire Kerr, Nora Shields, Melinda Randall, Adrienne Harvey, H Kerr Graham, Dinah Reddihough

Medical Papers and Journal Articles

Background: Cerebral palsy is a permanent disorder of posture and movement caused by disturbances in the developing brain. It affects approximately 1 in every 500 children in developed countries and is the most common form of childhood physical disability. People with cerebral palsy may also have problems with speech, vision and hearing, intellectual difficulties and epilepsy. Health and therapy services are frequently required throughout life, and this care should be effective and evidence informed; however, accessing and adopting new research findings into day-to-day clinical practice is often delayed.

Methods/Design: This 3-year study employs a before and after design to evaluate …


De Novo Identification Of Differentially Methylated Regions In The Human Genome, Timothy J. Peters, Michael J. Buckley, Aaron L. Statham, Ruth Pidsley, Katherine Samaras, Reginald V. Lord, Susan J. Clark, Peter L. Molloy Jan 2015

De Novo Identification Of Differentially Methylated Regions In The Human Genome, Timothy J. Peters, Michael J. Buckley, Aaron L. Statham, Ruth Pidsley, Katherine Samaras, Reginald V. Lord, Susan J. Clark, Peter L. Molloy

Medical Papers and Journal Articles

Background: The identification and characterisation of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in epigenetics. We present a novel method, DMRcate, that fits replicated methylation measurements from the Illumina HM450K BeadChip (or 450K array) spatially across the genome using a Gaussian kernel. DMRcate identifies and ranks the most differentially methylated regions across the genome based on tunable kernel smoothing of the differential methylation (DM) signal. The method is agnostic to both genomic annotation and local change in the direction of the DM signal, removes the bias incurred from irregularly spaced methylation sites, and …


Does Service Employees' Appearance Affect The Healthiness Of Food Choice?, Tabea: Benoit Huneke, Sabine Benoit, Anders Gustafsson Jan 2015

Does Service Employees' Appearance Affect The Healthiness Of Food Choice?, Tabea: Benoit Huneke, Sabine Benoit, Anders Gustafsson

Research Collection Lee Kong Chian School Of Business

Derived from previous research on social influence on food consumption and social comparison theory, this article examines the effect of service employees’ appearance on consumers’ food choice using an experimental study, involving a video manipulation and eye-tracking technique. The video shows a menu being proffered by a waitress whose degree of apparent healthiness varies (healthy, overweight, unhealthy lifestyle). The menu contains both healthy and unhealthy meal alternatives. The analysis of participants’ eye movements demonstrated that exposure to the overweight employee did not stimulate greater (i.e., earlier or longer) attention to unhealthy meal alternatives, whereas exposure to the employee who displayed …


Assessment Of Fundamental Movement Skills In Australian Children: The Validation Of A Fundamental Motor Skills Quotient (Fmsq), Beth Hands, Fleur Mcintyre Jan 2015

Assessment Of Fundamental Movement Skills In Australian Children: The Validation Of A Fundamental Motor Skills Quotient (Fmsq), Beth Hands, Fleur Mcintyre

Health Sciences Papers and Journal Articles

Objectives: The development of proficient fundamental movement skills (FMS) in children is important for physical, cognitive and social development, and to establish a foundation for an active lifestyle. Many teachers, coaches and physical activity program deliverers use real time observation of individual skill performances during physical activities to assess proficiency in young children. However, a valid method to quantify these observations to provide an overall motor competence is not available.

Design: A small pilot validation study using the Bland Altman method to compare scores on the McCarron Assessment of Neuromuscular Development (MAND) and a Fundamental Movement Skill Quotient (FMSQ) (M …


The Impact Of Maternal Gestational Stress On Motor Development In Late Childhood And Adolescence: A Longitudinal Study, Tegan Grace, Max Bulsara, Monique Robinson, Beth Hands Jan 2015

The Impact Of Maternal Gestational Stress On Motor Development In Late Childhood And Adolescence: A Longitudinal Study, Tegan Grace, Max Bulsara, Monique Robinson, Beth Hands

Health Sciences Papers and Journal Articles

The number and timing of stressors experienced during pregnancy were investigated using longitudinal data from the Western Australian Pregnancy (Raine) Study cohort (N = 2,900). Motor development data were collected at 10 (n = 1,622), 14 (n = 1,584), and 17 (n = 1,222) years using the McCarron Assessment of Neuromuscular Development. Linear mixed models were used to examine the effect of stress on motor development, accounting for repeated measures. Number of stressful events and mean Neuromuscular Development Index were negatively related (β = −1.197, p = .001). Stressful events experienced in late pregnancy were negatively related with offspring motor …


Empowerment Of Young People Who Have A Parent Living With Dementia: A Social Model Perspective, Karen Hutchinson, Chris Roberts, Michele Daly, Caroline Bulsara, Susan Kurrle Jan 2015

Empowerment Of Young People Who Have A Parent Living With Dementia: A Social Model Perspective, Karen Hutchinson, Chris Roberts, Michele Daly, Caroline Bulsara, Susan Kurrle

Health Sciences Papers and Journal Articles

Objectives: Socially constructed disablement has marginalised young people in families where a parent has younger onset dementia (YOD). This has contributed to inadequate societal support for their complex situation. Impacts on such young people include significant involvement with mental health services for themselves. In this paper we explored the young people’s lived experiences in these families and the influencing factors to enable these young people to be included and supported within their community.

Methods: In this qualitative research study the social model of disability was used as the theoretical framework in conducting a thematic analysis of interviews with 12 participants. …


Comparative Analysis Of Development And Survival Of Two Natal Fruit Fly Ceratitis Rosa Karsch (Diptera, Tephritidae) Populations From Kenya And South Africa, Chrysantus M. Tanga, Aruna Manrakhan, John Henry Daneel, Samira A. Mohamed, Khamis Fathiya, Sunday Ekesi Jan 2015

Comparative Analysis Of Development And Survival Of Two Natal Fruit Fly Ceratitis Rosa Karsch (Diptera, Tephritidae) Populations From Kenya And South Africa, Chrysantus M. Tanga, Aruna Manrakhan, John Henry Daneel, Samira A. Mohamed, Khamis Fathiya, Sunday Ekesi

All Peer-Reviewed Publications

Comparative analysis of development and survivorship of two geographically divergent populations of the Natal fruit fly Ceratitis rosa Karsch designated as C. rosa R1 and C. rosa R2 from Kenya and South Africa were studied at seven constant temperatures (10, 15, 20, 25, 30, 33, 35 °C). Temperature range for development and survival of both populations was 15-35 °C. The developmental duration was found to significantly decrease with increasing temperature for C. rosa R1 and C. rosa R2 from both countries. Survivorship of all the immature stages of C. rosa R1 and C. rosa R2 from Kenya was highest over …


Unpacking Postharvest Losses In Sub-Saharan Africa: A Meta-Analysis, Hippolyte Affognon, Christopher Mutungi, Pascal Sanginga, Christian Borgemeister Jan 2015

Unpacking Postharvest Losses In Sub-Saharan Africa: A Meta-Analysis, Hippolyte Affognon, Christopher Mutungi, Pascal Sanginga, Christian Borgemeister

All Peer-Reviewed Publications

Reducing postharvest losses (PHL) is a key pathway to food and nutrition security in sub-Saharan Africa. However, knowledge of PHL magnitudes is limited. A meta-analysis has been conducted to expose nature and magnitude of PHL, and the kinds of interventions that have been attempted to mitigate the losses. Findings reveal inadequacies of loss assessment methodologies that result in inaccurate PHL estimates. Moreover, losses are often economic rather than physical product losses. Overall, technologies for loss mitigation fail to address dynamics of supply chains. Consequently, rigorous PHL assessment using systematic methodologies, as well as holistic approaches for losses mitigation are in …


An Intersectional Perspective On Stigma As A Barrier To Effective Hiv Self-Management And Treatment For Hiv-Infected African American Women, Kimberly Adams Tufts Jan 2015

An Intersectional Perspective On Stigma As A Barrier To Effective Hiv Self-Management And Treatment For Hiv-Infected African American Women, Kimberly Adams Tufts

Ellmer School of Nursing Faculty Publications

Among those who are HIV-infected and striving to live well with HIV, African American women have poorer health outcomes and represent a higher portion of those women who die from HIV-related causes. Those health inequalities have been associated with the presence of social determinants of health such as stigma. This analytical review asserts that stigmas precipitated by gender, race, and class in the context of HIV-related stigma constitute substantial barriers to active engagement in HIV self-management, care, and treatment for HIV-infected African American women. The utility of the intersectionality framework for analyzing how these various stigmas interact to create unique …


Effectiveness Of Health Education Teachers And School Nurses Teaching Sexually Transmitted Infections/ Human Immunodeficiency Virus Prevention Knowledge And Skills In High School, Elaine A. Borawski, Kimberly A. Tufts, Erika S. Trapl, Laura L. Hayman, Laura D. Yoder, Loren D. Lovegreen Jan 2015

Effectiveness Of Health Education Teachers And School Nurses Teaching Sexually Transmitted Infections/ Human Immunodeficiency Virus Prevention Knowledge And Skills In High School, Elaine A. Borawski, Kimberly A. Tufts, Erika S. Trapl, Laura L. Hayman, Laura D. Yoder, Loren D. Lovegreen

Ellmer School of Nursing Faculty Publications

BACKGROUND- We examined the differential impact of a well-established human immunodeficiency virus (HIV)/sexually transmitted infections (STIs) curriculum, Be Proud! Be Responsible!, when taught by school nurses and health education classroom teachers within a high school curricula.

METHODS- Group-randomized intervention study of 1357 ninth and tenth grade students in 10 schools. Twenty-seven facilitators (6 nurses, 21 teachers) provided programming; nurse-led classrooms were randomly assigned.

RESULTS- Students taught by teachers were more likely to report their instructor to be prepared, comfortable with the material, and challenged them to think about their health than students taught by a school nurse. Both groups reported …


Scoring And Validation Of The Cystic Fibrosis Disclosure Questionnaire, Adrienne P. Borschuk Jan 2015

Scoring And Validation Of The Cystic Fibrosis Disclosure Questionnaire, Adrienne P. Borschuk

Theses and Dissertations

As more patients with cystic fibrosis (CF) are living into adulthood, patients may need to disclose their CF status to others, such as in romantic or professional settings. Patients who choose not to disclose their CF status may be limited in their closeness with others, which may negatively affect their psychological functioning and health-related quality of life. Few studies, however, have examined disclosure in CF, and currently no validated measures of CF disclosure exist. The purpose of this study was to explore CF disclosure in adults and validate a new assessment of CF disclosure, the Cystic Fibrosis Disclosure Scale (CFDS). …


Gas-Forming Nonstarter Lactorbacilli, Megan Jane Ostler, Jeff Broadbent, Craig J. Oberg, Donald J. Mcmahon Jan 2015

Gas-Forming Nonstarter Lactorbacilli, Megan Jane Ostler, Jeff Broadbent, Craig J. Oberg, Donald J. Mcmahon

Nutrition, Dietetics, and Food Sciences Faculty Publications

An obligatory heterofermentative lactic acid bacterium Lactobacillus wasatchii sp. nov. isolated from gassy Cheddar cheese was studied for growth, gas formation, salt tolerance and survival against pasteurization treatments at 63°C and 72°C. Initially, Lb. wasatchii was thought to only use ribose as a sugar source and we were interested in whether it could utilize galactose. Experiments to determine rate and extent of growth and gas production in carbohydrate restricted (CR) de Man, Rogosa, and Sharpe (MRS) medium under anaerobic conditions with various combinations of ribose and galactose at 12, 23, and 37°C were conducted with 23°C being the more optimum …


Growth And Gas Production Of A Novel Obligatory Heterofermentative Cheddar Cheese Nonstarter Lactobacilli Species On Ribose And Galactose, Western Dairy Center, Utah State University, Megan Jane Ostler, Jeff Broadbent, Craig J. Oberg, Donald J. Mcmahon Jan 2015

Growth And Gas Production Of A Novel Obligatory Heterofermentative Cheddar Cheese Nonstarter Lactobacilli Species On Ribose And Galactose, Western Dairy Center, Utah State University, Megan Jane Ostler, Jeff Broadbent, Craig J. Oberg, Donald J. Mcmahon

Nutrition, Dietetics, and Food Sciences Faculty Publications

An obligatory heterofermentative lactic acid bacterium, Lactobacillus wasatchii sp. nov., isolated from gassy Cheddar cheese was studied for growth, gas formation, salt tolerance, and survival against pasteurization treatments at 63°C and 72°C. Initially, Lb. wasatchii was thought to use only ribose as a sugar source and we were interested in whether it could also utilize galactose. We conducted experiments to determine the rate and extent of growth and gas production in carbohydraterestricted (CR) de Man, Rogosa, and Sharpe (MRS) medium under anaerobic conditions with various combinations of ribose and galactose at 12, 23, and 37°C, with 23°C being the optimum …


Motivation, Mindfulness, And Metabolic Factors Predicting Adolescent Adherence And Attrition In A Multidisciplinary Weight Management Program, Stephen Trapp Jan 2015

Motivation, Mindfulness, And Metabolic Factors Predicting Adolescent Adherence And Attrition In A Multidisciplinary Weight Management Program, Stephen Trapp

Theses and Dissertations

Estimated rates of obesity are notably high in the United States and pose a significant public health concern. A number of deleterious physical and psychosocial conditions are associated with pediatric obesity and the cost of its treatment is considerable. Accordingly, the number of weight management treatments has increased to meet this growing public health challenge. Unfortunately, insufficient participation in weight management treatment, namely low adherence and high attrition, often impede the effectiveness of these programs. Although the barriers associated with inadequate adherence and elevated rates of attrition are documented, there is a dearth of research on the predictors of the …


Emergent Non-Consumptive Predator Effects Alter Habitat Colonization By Dipteran Prey, Ethan G. Staats Jan 2015

Emergent Non-Consumptive Predator Effects Alter Habitat Colonization By Dipteran Prey, Ethan G. Staats

Theses and Dissertations

When ovipositing, prey organisms avoid habitat patches containing predator cues because predators consume, and negatively affect the fitness of their prey. Richness of predator species often enhances the strength of consumptive predator effects, but little is known about how multiple predators combined affect prey non-consumptively. We quantified dipteran colonization in aquatic mesocosms in response to varied predator richness. Multiple predator species combined reduced oviposition by Culex mosquitoes, chironomid midges, and the general colonizing dipteran community more than predicted by the effects of the independent predator species. Previous research which quantifies effects of multiple predators on prey as prey abundance, but …


Prothonotary Warbler Nestling Diet And Growth In Response To Variation In Aquatic And Terrestrial Food Availability, Jenna C. Dodson Jan 2015

Prothonotary Warbler Nestling Diet And Growth In Response To Variation In Aquatic And Terrestrial Food Availability, Jenna C. Dodson

Theses and Dissertations

Food supply has been suggested as the main determinant of reproductive success in birds. Riparian species can take advantage of seasonal pulses of both terrestrial and aquatic prey, though aquatic resources are often overlooked in studies of diet and reproductive ecology. This study investigates the flux of both aquatic (mayfly) and terrestrial (caterpillar) prey resources and nestling diet of the Prothonotary Warbler throughout the breeding season in two eastern Virginia sites. One site had significantly higher aquatic prey (mayfly) availability. Nestling diet was generally reflective of prey availability, and nestlings grew faster at the site with high aquatic prey availability. …


An Examination Of Weight, Weight Bias, And Health Care Utilization And Attitudes Among Emerging Adults, Jessica M. Mccauley Jan 2015

An Examination Of Weight, Weight Bias, And Health Care Utilization And Attitudes Among Emerging Adults, Jessica M. Mccauley

Theses and Dissertations

Individuals with overweight/obesity have been found to exhibit more negative attitudes toward health care and disproportionate rates of health care delay and avoidance, compared to their healthy weight peers. The present study sought to examine potential mechanisms through which weight status influences health care utilization and attitudes. Six hundred and thirty-three students completed a questionnaire measuring weight status, perceived weight bias, patient-provider relationship, and health care utilization and attitudes. Although the majority of the paths in the proposed theoretical mediation model were supported by the present findings, there was no support for the anticipated link between perceived weight bias and …


Nourish-C: Implementing A Family Based Weight Loss Intervention In A Church Community, Jacqueline Woods Jan 2015

Nourish-C: Implementing A Family Based Weight Loss Intervention In A Church Community, Jacqueline Woods

Theses and Dissertations

Increasing rates of obesity across all race, ethnic, gender, and age groups over the past thirty years have generated significant public health concern. Black children face disproportionately higher risk for overweight and obesity compared with their White peers. Substantial evidence suggests that parent involvement improves pediatric obesity treatment outcomes. Moreover, churches are feasible and culturally congruent places to host health promotion interventions within the Black community. The current study examined the feasibility of disseminating an existing pediatric obesity intervention, NOURISH, in Black church communities. Twenty-five families participated in baseline assessment of the NOURISH-C. Five churches hosted the intervention and eight …


Characterizarion Of The Regulation And Function Of Neisseria Gonorrhoeae Tonb-Dependent Transporters: Tdfg, Tdfh And Tdfj, Sophonie Jean Jan 2015

Characterizarion Of The Regulation And Function Of Neisseria Gonorrhoeae Tonb-Dependent Transporters: Tdfg, Tdfh And Tdfj, Sophonie Jean

Theses and Dissertations

The obligate human pathogen Neisseria gonorrhoeae successfully overcomes host strategies to limit essential nutrients, termed “nutritional immunity” by expression of TonB-dependent transporters (TdTs): outer membrane receptors that facilitate nutrient transport in an energy-dependent manner. N. gonorrhoeae encodes eight TdTs, five of which facilitate utilization of iron or iron-chelates from host derived proteins including transferrin, lactoferrin and hemoglobin, in addition to siderophores from neighboring bacteria. The transferrin utilization system was previously shown to be critical for establishing infection in human males; demonstrating the possible contributions of TdTs to gonococcal pathogenesis. As such, studies describing the biological function and contribution to pathogenesis …


Effects Of Constant Vs. Fluctuating Temperatures On Performance And Life History Of The Herbivorous Pest Lymantria Dispar (Lepidoptera: Eribidae), Brendan E. Sostak Jan 2015

Effects Of Constant Vs. Fluctuating Temperatures On Performance And Life History Of The Herbivorous Pest Lymantria Dispar (Lepidoptera: Eribidae), Brendan E. Sostak

Theses and Dissertations

The role of temperature variation in organismal performance is understudied, but is critically important for understanding the response of biodiversity to climate change. To address this issue in herbivorous insects, I studied the direct and interactive effects of thermal regime (constant vs. fluctuating temperatures) and nutrition (dietary nitrogen) on gypsy moth (Lymantria dispar) performance under laboratory conditions. Predictions for differences between constant and fluctuating thermal conditions were derived from Jensen’s inequality, and artificial diets of differing nutritional quality were made by modifying nitrogen (casein) content. Larvae were reared in the laboratory under four temperature regimes (22°C constant, 22°C …


Investigating The Effects Of Obesity Prevention Campaigns, Courtney C. Simpson Jan 2015

Investigating The Effects Of Obesity Prevention Campaigns, Courtney C. Simpson

Theses and Dissertations

Public health campaigns might not be universally helpful and could have detrimental consequences. The current investigation explored the effects of obesity prevention campaigns. Their impact was assessed using an experiment in which participants were randomized to view either weight focused obesity prevention campaigns or obesity prevention campaigns that did not use weight related terms. Results demonstrated that compared with campaigns without weight related terminology, weight focused campaigns increased negative perceptions of obesity and decreased self-efficacy for health behavior change. No differences in body satisfaction, thin-ideal internalization, state anxiety, or frequency of positive health behaviors were found based on the type …


Enhanced Epithelial-To-Mesenchymal Transition Associated With Lysosome Dysfunction In Podocytes: Role Of P62/Sequestosome 1 As A Signaling Hub, Guangbi Li Jan 2015

Enhanced Epithelial-To-Mesenchymal Transition Associated With Lysosome Dysfunction In Podocytes: Role Of P62/Sequestosome 1 As A Signaling Hub, Guangbi Li

Theses and Dissertations

Autophagy is of importance in the regulation of cell differentiation and senescence in podocytes, the highly differentiated glomerular epithelial cells. It is possible that derangement of autophagy under different pathological conditions activates or enhances Epithelial-to-Mesenchymal Transition (EMT) in podocytes, resulting in glomerular sclerosis. To test this hypothesis, the present study produced lysosome dysfunction by inhibition of vacuolar- type H+-ATPase (V-ATPase) to test whether deficiency of autophagic flux enhances EMT in podocytes. By Western blot analysis, inhibition of lysosome function by V-ATPase inhibitor or its siRNA was found to induce a significantly enhanced EMT in cultured podocytes, as shown …