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Chemical Investigation Of Candidate Probiotics In Aquaculture And Formulation Of A Probiotic Agent For Oyster Larviculure, Christine Anh Dao

Open Access Dissertations

Aquaculture is a multi-billion dollar industry worldwide. The United States is a significant consumer to both fresh and marine aquaculture products. Aquaculture sales in Rhode Island have dramatically increased in the last 20 years. In Rhode Island nearly 4.3 million oysters were produced via aquaculture in 2012. Currently, hatcheries and nurseries in the United States produce large amounts of a variety of species of oysters, clams and scallops. Oysters are filter feeders and are exposed to many microbes in the hatchery. Infectious diseases from bacterial pathogens in the hatcheries can have serious impacts on production. Vibrio species are often responsible …

Design, Synthesis, And Evaluation Of Inhibitors Of Ispd And Ispe As Potential Antibacterial, Antimalarial, And Herbicidal Agents, Michael Philip Thompson

Graduate Research Theses & Dissertations

The 2-C-methyl-D-erythritol-4-phosphate pathway, or MEP pathway, has recently gained attention as being a prime target for inhibition of many pathogenic species due to the lack of analogous enzymes in humans and many higher eukaryotes that use the mevalonic acid pathway. Either the MEP pathway or mevalonic acid pathway are utilized by all living organisms to generate the molecules isopentenyl diphosphate, IPP, and dimethyallyl diphosphate, DMAPP, which in turn can be used to create a wide variety of necessary cellular components called isoprenoids, such as cholesterol, some vitamins, pigments, etc. The MEP pathway involves seven different enzymes, which are unique in …

Sushi And Sashimi: The Contaminated Bacteria And Helminthes, The Guidelines, Prasert Saichua, Amonrat Jumnainsong

Asian Medical Journal and Alternative Medicine

Sushi and sashimi are the fashionable dishes in Thailand over the last decade. The consumers believe that marine fish and other ingredients are the low calorie food and have various dietaries such as omega-3 polyunsaturated fatty acids, proteins and vitamins. However, several countries reported that the health risks of consuming sushi and sashimi are bacteria and helminthes infection. The contamination of these pathogens has been reported from many areas. In this paper, the illness from contaminated sushi and sashimi are reviewed. Additionally, the guidelines to control the quality in each step of sushi and sashimi preparing are noted. This paper …

The Mirage Of Curriculum Decentralization : A Case Study Of Local Stakeholders' Involvement In School-Based Curriculum Development (Sbcd) Policy Implementation In Indonesia, Muhamad Ali Akrom

Graduate Research Theses & Dissertations

This study examined local stakeholders' involvement in the School-Based Curriculum Development (SBCD) policy implementation in five elementary schools in a city in the southeastern region of Indonesia. An interpretive qualitative case study design was applied. Participants in the study consisted of principals, teachers, parents/School Committee members, and key officials from the local education authority. Four data collection strategies were employed in this study: semi-structured interviews, focus groups, observations, and document analysis. The data obtained were analyzed qualitatively using a constant comparative method. Nvivo 10 was also used to facilitate the analysis process.;Findings of the study indicated that the local stakeholders …

Site-Specific Differences In T Cell Frequencies And Phenotypes In The Blood And Gut Of Hivuninfected And Art-Treated Hiv+ Adults, Steven A. Yukl, Amandeep K. Shergill, Valerie Girling, Qingsheng Li, Maudi Killian, Lorrie Epling, Peilin Li, Philipp Kaiser, Ashley Haase, Diane V. Havlir, Kenneth Mcquaid, Elizabeth Sinclair, Joseph K. Wong

School of Biological Sciences: Faculty Publications

Gastrointestinal T lymphocytes are critical for mucosal immunity and HIV pathogenesis, yet little is known about normal T cell numbers and phenotypes in different regions of the gut, or the degree to which ART can restore levels to those of HIV-uninfected individuals. To investigate these questions, we measured T cell frequencies and markers of memory, activation, anergy, and homing in the blood, ileum, and rectum of HIV- and ART-suppressed HIV+ adults. In HIV- individuals, T cell frequencies and phenotypes differed significantly between sites. Compared to HIV- adults, HIV+ adults had lower absolute CD4+T cell counts in the ileal lamina propria …

Linkages Between Concentrated Animal Feeding Operation (Cafo) Expansion And County Board Politics In Rural Illinois, Eric A. Sterling

Graduate Research Theses & Dissertations

Concentrated Animal Feeding Operations (CAFOs) are rapidly expanding in rural Illinois. This research explores the political power linkages between county boards and corporate entities in four Illinois counties. The hypothesis is that collusion and impropriety within county board politics and CAFO expansion in rural Illinois are attributed to stakeholder influence and power at the local county government level. My research revealed a connection between ownership of CAFOs, county board political power, and endorsement of expansion. Utilizing Walter Goldschmidt's method of a controlled comparison, the research analyzes two CAFO inundated counties (Pike and Adams) with two less affected counties (LaSalle and …

Methionine Aminopeptidase Enzyme Inhibitors As Promising Targets Toward Discovery Of Novel Anti-Infective Agents, Phumvadee Wangtrakuldee

Graduate Research Theses & Dissertations

Methionine aminopeptidases are ubiquitous enzymes that are essential for the survival of numerous bacteria, removing N-terminal methionines from nascent proteins to initiate post-secondary modification. The ultimate goal of this study is to identify selective inhibitors targeting methionine aminopeptidases from infective organisms, including Burkholderia pseudomallei, Plasmodium falciparum, and Rickettsia prowazekii, to generate novel anti-infective agents.;Plasmodium falciparum methionine aminopeptidase ( PfMetAP2) was expressed and purified in-house from truncated sequence of PfMetAP2, while Burkholderia pseudomallei methionine aminopeptidase 1 and Rickettsia prowazekii methionine aminopeptidase 1 was obtained from Seattle Biomedical Research Institute. Our studies reveal the ability of nitroxoline analogs to inhibit both Burkholderia …

The Perceptions Of The Preparedness Of Medical Graduates To Take On Internship Responsibilities In Low Resource Hospitals In Kenya, Patricia Muthaura, Tashmin Khamis

Obstetrics and Gynaecology, East Africa

The Aga Khan University is developing an Undergraduate Medical Education (UGME) curriculum for implementation in East Africa in 2016, which aims to serve the health needs of the populations there. Pilot focus group discussions of recent interns were conducted at the Aga Khan University Hospital, Nairobi to find out: (1) If Kenyan medical students are adequately prepared for their roles as interns in low resource hospitals upon graduation from medical schools; (2) The likely clinical conditions that interns will face in low resource hospitals in Kenya; and (3) How might the UGME curriculum best prepare interns for their roles in …

Analysis And Simulation For Homogeneous And Heterogeneous Sir Models, Joseph Wilda

Electronic Theses and Dissertations

In mathematical epidemiology, disease transmission is commonly assumed to behave in accordance with the law of mass action; however, other disease incidence terms also exist in the literature. A homogeneous Susceptible-Infectious-Removed (SIR) model with a generalized incidence term is presented along with analytic and numerical results concerning effects of the generalization on the global disease dynamics. The spatial heterogeneity of the metapopulation with nonrandom directed movement between populations is incorporated into a heterogeneous SIR model with nonlinear incidence. The analysis of the combined effects of the spatial heterogeneity and nonlinear incidence on the disease dynamics of our model is presented …

Is Community-Based Work Compatible With Data Collection?, John W. Murphy, Berkeley A. Franz, Karen A. Callaghan

The Journal of Sociology & Social Welfare

Although community-based projects have introduced a successful model for addressing many social problems, less consideration has been given to how such projects should be evaluated. This paper considers whether the philosophy underlying community-based practice is compatible with data collection. Specifically at issue is whether empirical indicators are helpful to summarize a project. Although having valid knowledge is important, this paper makes a distinction between merely collecting data versus understanding the course of a project. The key point is that community participation requires a unique perspective on how knowledge is negotiated and interpreted.

Journal Of Sociology & Social Welfare Vol. 42, No. 4 (December 2015)

The Journal of Sociology & Social Welfare

Table of Contents

LETTER FROM THE EDITOR: EMPIRICISM. - Robert D. Leighninger, Jr.

IS COMMUNITY-BASED WORK COMPATIBLE WITH DATA COLLECTION? - John W. Murphy, Berkeley A. Franz, and Karen A. Callaghan

IMPACT OF COMMUNITY INVESTMENT IN SAFETY NET SERVICES ON TRAJECTORIES OF UNSHELTERED HOMELESSNESS AMONG VETERANS - Ann Elizabeth Montgomery, Jamison D. Fargo, and Thomas H. Byrne

EBB AND FLOW: A MULTIPLE STREAMS POLICY ANALYSIS OF CHANGE IN KANSAS DOMESTIC VIOLENCE POLICY - Emily Bell-Sepulveda, Juliana Carlson, and Sara Rust-Martin

CAN PEOPLE EXPERIENCING HOMELESSNESS ACQUIRE FINANCIAL ASSETS? - Allison De Marco, Molly De Marco, Alexandra Biggers, Maggie West, Jonathan Young, …

Determinants Of Hiv Stigma Among Healthcare Workers In Ghana, Catherine Gyamfua Dawson-Amoah

Walden Dissertations and Doctoral Studies

HIV-related stigma and discrimination is a complex concept that affects HIV reduction interventions. HIV-related stigma occurs among healthcare providers resulting in reduction of quality of care of people living with HIV. Social psychological research into stigma reduction has led to the development of many stigma reduction interventions, but has not resolved the underlying problem. This study was designed to identify predictors of stigmatizing behavior among healthcare workers in Ghana using the social cognitive theory (SCT) for use in developing an evidence-based intervention. The study used a cross-sectional research design incorporating a preexisting survey, Measuring HIV Stigma and Discrimination Among Health …

Associative Factors Of Acculturative Stress In Latino Immigrants, Sam Kedem

Walden Dissertations and Doctoral Studies

For the past 200 years, Latinos have comprised the largest, consistent category of immigrants in the United States. This influx has created a need for culturally competent psychological treatment of a population that suffers from acculturative stress, defined as the stress a minority member experiences while trying to adjust to the culture of the majority. Researchers have studied Latino immigrants' enduring trials as they adjust to life in the United States. Nevertheless, there is limited research on the quantification of factors contributing to acculturative stress. Based on the conceptual framework of bidimensional acculturation and Latina/o critical race theory, predictors of …

Sociodemographic Predictors Of Medication Nonadherence Among Latinos Diagnosed With Diabetes Type Ii, Bianca L. Tristan

Walden Dissertations and Doctoral Studies

Latinos of low socioeconomic status are disproportionately affected by diabetes Type II complicated by poor adherence to diabetes Type II medications and management programs. Self-management of diabetes Type II is a tool used to teach health education to patients with diabetes. The objective of this retrospective quantitative study was to explore if there are predictors of nonadherence to diabetes Type II medications and programs among Latinos with diabetes Type II. Data from 200 patient records from a community clinic in Fresno County California were analyzed using both bivariate and multivariate analysis. Selected sociodemographic independent variables were age, gender, income, migrant …

The Role Of Sociodemographic Characteristics And Antiretroviral Prophylaxis On Risky Sexual Behavior Among Men Who Have Sex With Men, Leonard Obodo

Walden Dissertations and Doctoral Studies

Recent multicenter, randomized, double blind clinical trials have shown no association between HIV preexposure prophylaxis (PrEP) and increased sexual risk behavior among high-risk men who have sex with men (MSM). However, little research has been conducted under natural conditions devoid of clinical trial controlled environment to confirm the lack of association between PrEP and increased sexual risk behavior. Also, research has shown conflicting associations between sociodemographic characteristics and sexual risk behavior among MSM. In this cross-sectional, web-based, primary data analysis, MSM who reside in United States of America (USA) and who make use of PrEP for HIV prevention were examined …

Use Of An Electronic Educational Module To Educate Advanced Practice Nurses On Preventive Care Protocol For Immunocompromised Patients, Simi Jesto Joseph Dr, Audrey Klopp Dr

Manipal Journal of Nursing and Health Sciences

Immunocompromised patients are at increased risk of infections and certain cancers due to the immunosuppressed body as well as the immunosuppressive agents. Despite American national organizations’ specific guidelines for immunocompromised patients, reported vaccination rates and provider compliance on preventive services is low. The aim of this study was to assess knowledge, attitude and clinical practice among Advanced Practice Nurses (APN) in preventive care for immunocompromised patients and educating APNs to improve their knowledge and practice skills using an evidence-based preventive care protocol. Methods: APN members of Illinois Society of Advanced Practice Nurses (ISAPN) organization were surveyed by a needs assessment …

Clinico Epidemiological Profile Of Hiv-Tb Co-Infected Patients In Coastal South India, Bhaskaran Unnikrishnan Dr, Ramesh Holla Dr, Darshan B. B Dr, Arjun B. Y Dr

Manipal Journal of Nursing and Health Sciences

Introduction: Human Immunodeficiency Virus (HIV) and Tuberculosis (TB) co-infection is considered to be one of the important public health problems globally. Tuberculosis is a leading cause of mortality among people living with HIV/AIDS. Objectives: To find out the trends of HIV and TB co-infection, socio-demographic and clinical profile of HIV and TB co-infected patients. Methods: A hospital based descriptive study was done at a tertiary care teaching hospital in Mangalore. The hospital records of all HIV-TB co-infected patients admitted between January 2008 and December 2013 were reviewed and data were captured in data capture sheet. The data obtained was analysed …

Multiple Fungal Brain Abscesses In A Neonate: Successful Treatment With Liposomal Amphotericin B, Leslie Lewis Dr, Jayashree P Dr, Y Ramesh Bhat Dr

Manipal Journal of Nursing and Health Sciences

Invasive fungal infections are common among infants hospitalized in the Neonatal Intensive Care Unit (NICU). Central Nervous System (CNS) involvement occurs in two third of the disseminated fungal sepsis. Fungal cerebral abscess is one of the severe complications of disseminated fungal sepsis. We report a case of multiple fungal brain abscesses in a term neonate, which was successfully treated with Liposomal Amphotericin B.

Faculty Masthead, Mjlst Editorial Board

Minnesota Journal of Law, Science & Technology

No abstract provided.

Regime Type And Healthcare Systems: A Global Quantitative Analysis, R. L. Barr

Honors Theses

This thesis examines the link between regime type and healthcare systems. After reviewing literature that examines regime type, social spending, and healthcare, as well as a more specific example of regime change in Chile, it undertakes a multivariate regression analysis of 183 countries. It concludes that democracies have significantly better healthcare-system indicators, but that environmental variables, such as Latitude and Percentage of Rural Population, are more significant predictors of healthcare. It concludes that, while regime type is an important factor, dealing with ecological and locational problems of a country, such as combating tropical diseases and expanding access to infrastructure, are …

Acceptance And Uptake Of Influenza Vaccination By Health Care Workers, Leshonda Wallace

Walden Dissertations and Doctoral Studies

Influenza is a preventable infectious disease, against which vaccination is the primary means of protection. Health care workers (HCW) are among the most vulnerable to the illness and are likely to be sources of infection transmission while caring for patients. Circumstantial evidence suggests higher rates of vaccination coverage by HCW will coincide with a lower incidence of influenza transmission, yet a gap remains in the literature regarding governing health agencies' (i.e., licensing boards, medical and nursing associations) influence on the influenza vaccination practices of their constituents. Moreover, discrepancies exist between governing health agencies' and the National Vaccine Advisory Committee's recommendations …

Educational Intervention To Impact Parental Decisions To Consent To Human Papillomavirus Vaccine, Tawa Bimbola Ibikunle-Salami

Walden Dissertations and Doctoral Studies

Educational Intervention to Impact Parental Decisions to Consent to Human Papillomavirus Vaccine

by

Tawa B. Ibikunle-Salami

MSN, Indiana Wesleyan University, 2010

BSN, Indiana Wesleyan University, 2005

Project Submitted in Partial Fulfillment

of the Requirements for the Degree of

Doctor of Nursing Practice

Walden University

September 2015

Human Papillomavirus (HPV) is a global health issue that is transmitted sexually and affects both genders. Evidence shows that approximately 79 million people are affected in the United States with 14 million newly affected yearly. The Centers for Disease Control and Prevention indicates that teens and young adults under age 25 are at particular …

Concordance Of Genotyping And Phenotyping In The Classification Of Methicillin-Resistant Staphylococcus Aureus, Ali M. Bazzi

Walden Dissertations and Doctoral Studies

Methicillin-resistant Staphylococcus aureus (MRSA) strains have spread in Saudi Arabia, increasing morbidity, mortality, and financial burdens. Recent studies have suggested the phenotyping methods typically used to classify MRSA as either health care MRSA (HA-MRSA) or community-associated MRSA (CA-MRSA) cases are unreliable, because they lack concordance with the results of genotyping. Yet the expense associated with genotyping precludes its use in the Saudi Aramco population in Saudi Arabia. The absence of a standardized and affordable method to classify MRSA into CA-MRSA and HA-MRSA has been a challenge for infection control programs in Saudi Arabia. The objective of this quantitative, secondary data …

Ventilator-Associated Pneumonia Prevention Bundle, Patricia Cal

Walden Dissertations and Doctoral Studies

Ventilator-associated pneumonia (VAP) is a serious complication in critically ill patients; it can prolong intubation, increase intensive care unit and hospital length of stay, and increase mortality to twice the level of patients who do not develop VAP. The purpose of this project was to determine the effect of an evidence-based educational program to prevent VAP on ICU nurses' actual and documented practices for preventing VAP. The research questions addressed whether an educational program focused on VAP prevention will affect critical care nurses' compliance with a VAP prevention bundle, and whether the education will result in maintenance of a rate …

Small Business Sustainability In The Salon Industry, Militea Johnson-Hilliard

Walden Dissertations and Doctoral Studies

Small businesses fail at high rates; 51% fail to succeed in business beyond the first 5 years. The purpose of this exploratory case study was to explore the strategies that salon business owners used to succeed in business. The sample comprised of 2 salon business owners in Savannah, Georgia who have been in business more than 5 years. The conceptual framework was based on the general systems theory. Data were collected from conducting semistructured interviews with each business owner, a review of company business plans, direct observation of participants during client interaction in the salon, as well as member-checking interview …

Perception Of Anal Hpv Infection By Hiv-Positive Men Practicing Male-Male-Sex, Philecia Simone Mullings

Walden Dissertations and Doctoral Studies

Human papillomavirus (HPV) is a preventable, sexually transmitted infection whose prevalence has been rising dramatically among men who have sex with men (MSM) in the United States since 2008. The HPV infection rate for MSM is rising even faster for MSM who are infected with the human immunodeficiency virus (HIV) and for those who have developed acquired immune deficiency syndrome (AIDS). It is not clear whether MSM in general and MSM with HIV have the knowledge necessary to prevent infection of themselves and their partners. This phenomenological study explored the knowledge, health perceptions, attitudes, and norms of the community of …

Barriers To The Influenza Vaccination In Veterans, Zina Floyd

Walden Dissertations and Doctoral Studies

Influenza is the eighth leading cause of death in the United States, accounting for 56,000 deaths annually and leading to an average of more than 200,000 hospitalizations every year. Adults 65 years of age and older account for 50% to 60% of influenza-related hospital admissions and an estimated 90% of influenza-associated deaths occur in people age 65 and older. During the 2011 to 2012 influenza season, approximately 50 % of veterans between 45 and 70 years of age refused the influenza vaccine within the metro-area outpatient Veteran Administration (VA) facility in Atlanta, Georgia. The aim of this project was to …

Discovery Of Resistance-Reversing Agents In Antibiotic Resistant Strains Of Escherichia Coli And Klebsiella Pneumoniae From Natural Product Libraries, Andrew B. Watkins

Honors Theses

Objective: The objective of this exploratory research is to discover compounds, particularly from natural products, that inhibit ESBL, KPC, and NDM-1 mechanisms of antibiotic resistance in the Gram negative bacteria Escherichia coli and Klebsiella pneumoniae. Methods: This objective will be accomplished utilizing a high-volume bioassay testing natural product samples from the National Center for Natural Products Research. This assay tests samples against 6 different strains of bacteria known to express β-lactamases in the presence and absence of sub-inhibitory concentrations of the test antibiotic. By structuring the assay in this way, differentiation may be made between the inherent antibacterial activity of …

The Use Of Sodium Bicarbonate In The Treatment Of Acidosis In Sepsis: A Literature Update On A Long Term Debate, Dimitrios Velissaris, Vesilios Karamouzos, Nikolaos Ktenopoulos, Charalampos Pierrakos, Menelaos Karanikolas

Open Access Publications

No abstract provided.

Hemorrhagic Cystitis Requiring Bladder Irrigation Is Associated With Poor Mortality In Hospitalized Stem Cell Transplant Patients, Valary T. Raup, Aaron M. Potretzke, Brandon J. Manley, John A. Brockman, Sam B. Bhayani

Open Access Publications

No abstract provided.