Digital Commons Network^™

Pinching Pennies, Costing Dollars: Michigan's Offender Re-Entry System, Crystal A. Dussia

Senior Honors Theses and Projects

The current state of incarceration is a burden that every taxpayer bears. Through effective offender re-entry services, the financial, social, and physical burdens such as high crime rates, high recidivism rates, and the high cost of incarceration can be lessened for all citizens. Historical context establishes a foundation to be able to understand the current state of re-entry in Michigan as a small representation of the nation. The financial expenditures, social costs, and lack of evidence of past practice are explored. The content of this thesis is focused on Michigan within a national context of prison re-entry programs, history, and …

The Great Data Breach, De'andre M. Brown

Senior Honors Theses and Projects

This paper examines how Target Corporation dealt with their data breach when their network was infiltrated by hackers compromising the debit and credit card information of millions of customer's personal information including customer names, mailing addresses, phone numbers and e-mail addresses. Crisis communication models that are used to evaluate the effectiveness of corporations' handling crisis situations in a world where social media and speed dominate the news cycle.

Development And Maintenance Of Thymic Epithelial Microenvironment, Varan J. Singh

Dissertations and Theses

Thymus is a primary lymphoid organ responsible for proper development and selection Of T-­‐cells. The thymic microenvironment, however, undergoes age related involution, Resulting in a reduction of the repertoire of T-­‐cells that are produced, and a decreased Capacity to respond to new antigen. Even though significant thymic epithelial turnover occurs, it is unclear if postnatal thymic progenitors/stem cell are responsible for the maintenance of the TEC microenvironment. Here we use the K5rtTA:TetO-­‐H2BGFP transgenic model to identify a slow cycling potential stem cells/progenitor population in the postnatal thymus. These cells were isolated, expanded in culture, and successfully differentiated into adipocytes, chondrocytes …

Fall 2015

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Summer 2015

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Characterizing Nontarget Species Use At Bait Sites For White-Tailed Deer, Brent Bowman, Jerrold L. Belant, Dean E. Beyer Jr., Deborah Martel

Human–Wildlife Interactions

Baiting white-tailed deer (Odocoileus virginianus) has evolved into a controversial issue of wildlife management. During August–September 2012, we established a grid of 64 cameras in the Upper Peninsula of Michigan at sites baited with corn that simulated legal bait sites for white-tailed deer to characterize presence, diversity, and frequency of species use. We detected >20 species of wildlife that visited bait sites. We categorized 3,177 of 11,194 images as independent detections (i.e., species detected >1 hour apart). White-tailed deer had the greatest detection rate (47%), but overall detections of nontarget species was slightly greater (53%). Most frequent nontarget …

Winter Habitat Associations Of Blackbirds And Starlings Wintering In The South-Central United States, Matthew Strassburg, Shawn M. Crimmins, Patrick C. Mckann, Wayne E. Thogmartin

Human–Wildlife Interactions

Birds can cause extensive crop damage in the United States. In some regions, depredating species comprise a substantial portion of the total avian population, emphasizing their importance both economically and ecologically. We used the National Audubon Society Christmas Bird Count data from the south-central United States and mixed-effects models to identify habitat factors associated with population trend and abundance for 5 species: red-winged blackbird (Agelaius phoeniceus), common grackle (Quiscalus quiscula), rusty blackbird (Euphagus carolinus), Brewer’s blackbird (Euphagus cyanocephalus), and European starling (Sturnus vulgaris). Overall, we found positive associations between bird …

Bioaccumulation Of Mercury In Wilson’S Snipe From Alabama, Lindsay J. Brooks, Joshua W. Campbell, Julia W. Murphy

Human–Wildlife Interactions

Mercury is a persistent, toxic heavy metal that can bioaccumulate in organisms, causing diseases and other health problems. Wilson’s snipe (Gallinago delicata) feed primarily on aquatic invertebrates, which makes them prone to mercury bioaccumulation. In this study, we measured total mercury in Wilson’s snipe. Total mercury was measured in the feathers and muscle tissue. Mean concentration (ppm ± SE) of mercury was 1.33 (± 0.22) and 0.087 (± 0.03) in the feathers and muscle tissue, respectively. Mercury concentration was significantly higher in feathers than muscle. Our data indicate that Wilson’s snipe, an aquatic-invertebrate predator that bioaccumulates mercury from …

Legal Myths Of Ebola Preparedness And Response, James G. Hodge Jr.

Notre Dame Journal of Law, Ethics & Public Policy

In March 2014, Ebola viral disease (“EVD”) emerged from several

West African countries as a substantial threat to global health.

Through a series of core legal powers pursuant to its declaration of a

public health emergency of international concern (“PHEIC”) on

August 8, 2014, the World Health Organization (“WHO”) averted a

global health disaster by requiring member countries to engage in mul- tiple public health interventions. These efficacious WHO-mandated

measures included implementation of border closures to limit the

spread of EVD within and outside of countries like Guinea, Liberia,

Senegal, and Sierra Leone. Industrialized nations, including the

United States, responded …

Prevalence And Distribution Of Ranavirus, Chytrid Fungus, And Helminths In North Dakota Amphibians, Melanie Paige Firkins

Theses and Dissertations

Worldwide reports of population declines and extinctions of amphibians have continued for at least two decades. Factors frequently reported in association with these declines include habitat loss, infectious diseases, and environmental degradation. Three sources of disease have been a concern for amphibians: chytrid fungus, Ranavirus, and some helminth parasites. Much of the existing reporting on disease results from anecdotal accounts associated with localized outbreaks, but understanding the scope and dynamics of infectious agents in host populations requires a regional perspective. My objectives were to estimate geographic distribution and prevalence of Ranavirus, chytrid fungus, and helminths in amphibians across the state …

High-Risk Febrile Neutropenia And Its Management In Childrenwith Solid Tumors And Lymphoma, Doğan Köse, Meli̇ke Emi̇roğlu, Yavuz Köksal

Turkish Journal of Medical Sciences

Background/aim: The clinical characteristics and treatment results of febrile neutropenia attacks that occurred in patients with lymphoma and solid tumors were analyzed. Materials and methods: A total of 50 patients with 94 high-risk attacks were evaluated for malignant diseases in this study. Results: The fever etiology was determined as clinical (50%), microbiological (5.31%), clinical-microbiological (5.31%), or unknown (39.3%). A few of the attacks (21.3%) were observed in lymphoma cases and 77.7% were observed in patients with solid tumors. Patients who were in remission had 59.6% of the attacks, and 39.4% occurred in patients not in remission. Among the groups tested, …

Infectious Disease Outbreaks And Increased Complexity Of Care, Joan Musau, A. Baumann, C. Kolotylo, T. O’Shea, A. Bialachowski

School of Nursing & Midwifery, East Africa

Aim: This study examined the effects of healthcare-associated infectious disease outbreaks on nurses’ work in a large acute care hospital in Ontario, Canada.

Background: The incidence of healthcare-associated infections has increased. Previous research focuses on epidemiology, healthcare systems, and the economic burden of outbreaks. Few published studies focus on the impact of outbreaks on nurses’ work in acute care facilities.

Introduction: Since the severe acute respiratory syndrome epidemic in 2003, combating infectious diseases has become a key issue. Hospitals have implemented measures related to healthcare-associated infections. However, nurses experience challenges in preventing, controlling, and contending with outbreaks.

Methods: A retrospective …

Exploring Unprotected Anal Intercourse Among Newly Diagnosed Hiv Positive Men Who Have Sex With Men In China: An Ethnographic Study, Haochu Li, Eleanor Holroyd, Joseph Lau

School of Nursing & Midwifery, East Africa

Background: Unprotected anal intercourse (UAI) is a major pathway towards secondary HIV transmission among men who have sex with men (MSM). We explored the socio-cultural environment and individual beliefs and experiences conducive to UAI in the context of Southern China.

Methods: We employed an ethnographic approach utilizing a socio-ecological framework to conduct repeated in-depth interviews with thirty one newly diagnosed HIV positive MSM as well as participant observations in Shenzhen based healthcare settings, MSM venues and NGO offices.

Results: Some men (6/31) reported continuing to practice UAI after an initial diagnosis of being HIV positive. For MSM who had existing …

Stigma, Subsistence, Intimacy, Face, Filial Piety, And Mental Health Problems Among Newly Hiv-Diagnosed Men Who Have Sex With Men In China, Haochu (Howard) Li, Eleanor Holroyd, Joseph Lau, Xiaoming Li

School of Nursing & Midwifery, East Africa

High rates of mental health problems among people living with HIV (PLWH) have been widely reported in the literature; however, an understanding of the socioecological contexts of these presentations remains limited, particularly in China. In order to explore potential socioecological factors associated with mental health problems among newly diagnosed HIV-infected migrant men who have sex with men (MSM), we employed a life profile approach conducting semistructured in-depth interviews with 31 newly diagnosed HIV-infected MSM residing in a city in Southern China. Participants’ life profile accounts outlined their concerns, including internalized stigma, subsistence living, difficulties finding a lover or a stable …

Evaluation Of An Assertive Continuing Care Program For Hispanic Adolescents, Eric Strunz, Joanna Jungerman, Juliet Kinyua, Paula M. Frew

Environmental & Global Health Faculty Research

PURPOSE: This study evaluated an Adolescent Community Reinforcement Approach (A-CRA) and Assertive Continuing Care (ACC) program targeting Hispanic adolescents at risk for substance abuse.

Ebola Viral Disease: What Should Be Done To Combat The Epidemic In 2014?, Ali̇ye Baştuğ, Hürrem Bodur

Turkish Journal of Medical Sciences

Ebola virus disease (EVD) was defined first in 1976. Since then, more than 24 epidemics have been reported from Africa, predominantly with the Zaire species. On 21 March 2014, the current West Africa outbreak was reported by the World Health Organization, the largest one ever recorded. The Congo epidemic was reported in July 2014. It was considered that the two epidemics had unrelated origins with 96.8% identical genomic sequence of the virus. EVD outbreaks occurred in areas with limited resources but it has a potentially global effect due to the possibility of imported infection and the potential misuse of the …

Non-Coding Rnas Of The Q Fever Agent, Coxiella Burnetii, Indu Ramesh Warrier

Graduate Student Theses, Dissertations, & Professional Papers

Coxiella burnetii is an obligate intracellular bacterial pathogen that undergoes a biphasic developmental cycle, alternating between a small cell variant (SCV) and a large cell variant (LCV). Despite the remarkable niche and life cycle of C. burnetii, little is known about its modes of regulation and the roles that non-coding RNAs play in its growth and development. One such element is the intervening sequence (IVS); a 444-nt RNA element that is inserted within helix 45 of CoxiellaÆs precursor 23S rRNA. C. burnetii may have acquired IVS through horizontal transfer, and it has been subsequently maintained by all strains of C. …

Gender Differences In Clinical Characteristics And Outcome Of Acute Heart Failure In Sub-Saharan Africa: Results Of The Thesus-Hf Study, Okechukwu S. Ogah, Beth A. Davison, Karen Sliwa, Bongani M. Mayosi, Albertino Damasceno, Mahmoud U. Sani, Charles Mondo, Anastase Dzudie, Dike B. Ojji, Charles Kouam, Ahmed Suliman, Neshaad Schrueder, Gerald Yonga, Sergine Abdou Ba, Fikru Maru, Bekele Alemayehu, Christopher Edwards, Gad Cotter

Internal Medicine, East Africa

Background: The impact of gender on the clinical characteristics, risk factors, co-morbidities, etiology, treatment and outcome of acute heart failure in sub-Saharan Africa has not been described before. The aim of this study was to evaluate the sex diffe rences in acute heart failure in sub-Saharan Africa using the data from The sub-Saharan Africa Survey of Heart Failure (THESUS-HF).

Methods and results: 1,006 subjects were recruited into this prospective multicenter, international observational heart failure survey. The mean age of total population was 52.4 years (54.0 years for men and 50.7 years for women). The men were significantly older (p …

An Economic Analysis Of Food Safety And Public Health: Milk Pasteurization In The United States, Huiqiang Wang

Open Access Dissertations

My dissertation is a comprehensive economic history study to the public health impacts of milk pasteurization in the United States. It has four major focuses which are included into four chapters. Chapter I is a case study to the public health impact of Chicago’s pasteurization ordinance. This study sets up the causal relationship between milk pasteurization and health outcomes. Chapter II extends the new econometric tool, the synthetic control methods, from a single unit to multiple treated units. This chapter also measures the impacts of pasteurization ordinances in a group of cities. Chapter III is written from an econometric perspective. …

The I507-Atc→Att Silent Codon Change Contributes To The Misfolding Of ∆F508 Cftr, Vedrana Bali

All ETDs from UAB

Synonymous codon changes (SCCs) do not alter the amino acid sequence of proteins, but may significantly change the phenotype. The frequency of synonymous codons is species- and gene-specific, described as codon usage bias (CUB). Over the past 50 years, research has shown that SCCs affect protein biogenesis, development of human disorders and the function of recombinant proteins developed for therapeutic applications. However, the molecular mechanisms by which SCCs alter the function of gene products are not completely understood. In Chapter 2 we summarize present knowledge in this field. The most common cause of cystic fibrosis (CF) is the deletion of …

The Mspa Nanopore As A Sensor For Dna Sequencing, Mikhail Pavlenok

All ETDs from UAB

Nanopore sequencing is a novel and promising DNA sequencing method. This single molecule technique is capable of long reads, retains epigenetic information, and is inexpensive and fast. In this method ionic current is measured while single-stranded DNA is electrophoretically translocated through a nanometer-scale pore. Each passing nucleotide blocks current with characteristic amplitude and duration which are used to identify DNA sequence. MspA is the primary porin of M. smegmatis and mediates the diffusion of small, hydrophilic nutrients across the outer membrane. MspA is an octameric, channel-forming protein and represents the founding member of a new class of mycobacterial outer membrane …

Intestinal Microbiota And Its Role In Mucosal And Systemic Immune Responses, Qing Zhao

All ETDs from UAB

Host-microbiota mutualism is established with long-term co-evolution. The abundant and diverse microbes colonizing on the surface of the host’s body, especially those in the gastrointestinal (GI) tract, play an essential role in the development and maturation of the host’s immune system. Failure of intestinal microbial control may lead to the development of an array of autoimmune diseases, including inflammatory bowel disease (IBD). As a well-recognized inflammation mediator, Th17 cells are actually among the most abundant effector CD4+ T cells in the normal adult gut. What the role of intestinal Th17 cells is under steady state conditions and how the intestinal …

Faculty Publications 2014, Lsu Health Sciences Center New Orleans

Historical Faculty Publications

This Faculty bibliography contains 898 publications.

Spectrum 2015, Saint Mary's College Of California

The Undergraduate Spectrum

No abstract provided.

Is Conflict A Factor In A Population's Quality Of Life? A Comparative Study Of University Students In The Palestinian Territories And Jordan, Yara Asi

Electronic Theses and Dissertations

As nearly one third of the world's population lives in an area that is in some way touched by war, researchers have long been interested in the varied impacts of conflict on civilians. Many indicators, measuring both physical and mental constructs, have been assessed in war-torn populations from around the world, one of which is health-related quality of life (HRQoL). The occupied Palestinian Territories (oPt) are one region in which copious research on health indicators has been undertaken in an effort to understand how long-term conflict manifests itself in noncombatant populations. However, existing studies focus primarily on indicators within the …

Fmf Assay For Assessing Vaccine Generated Antibodies In A Biomimetic Manner, Vipra Dhir

Electronic Theses and Dissertations

Traditional functional assays such as hemagglutination inhibition (HAI) and micro-neutralization (MN) assays have been routinely used for assessing the vaccine response, since influenza vaccine has been administered in people (1940). Such assays are not always predictive regarding the protection conferred by the influenza vaccine and are not able to monitor neutralization related to stem region of influenza hemagglutinin responsible for virus membrane fusion in the endosomes. In order to study Influenza vaccine response in a more biomimetic manner and overcome the deficiencies of the traditional functional assays, we developed a fluorescent membrane fusion assay (fMF). The assay uses viruses labeled …

Canadian Prison Needle-Exchange Programs: Can The Health Benefits Overcome The Current Legal Barriers?, Adrien Iafrate

Dalhousie Journal of Legal Studies

The incidence of HIV and Hepatitis C is significantly higher in Canadian federal penitentiaries than among the general public, as are the transmission rates of these two diseases. These disproportionate rates of infection are largely attributed to the sharing of needles among inmates who are addicted to intravenous drugs. This has created a serious public health risk for all federal inmates as well as the general public, since many of these inmates will be released back into society. In response to this risk, the Correctional Service of Canada asked the Public Health Agency of Canada (PHAC) to study the effectiveness …

An O'Neill Institute Briefing Paper: Ebola, The World Health Organization, And Beyond: Toward A Framework For Global Health Security, Lawrence O. Gostin, Eric A. Friedman, Daniel Hougendobler

Georgetown Law Faculty Publications and Other Works

The West African Ebola epidemic has demonstrated that the world remains ill-prepared to respond to infectious disease outbreaks. A host of institutions are now reviewing what went wrong, and new institutions are being considered, including an African Centers for Disease Control and Prevention and World Bank-initiated Pandemic Emergency Facility. The World Health Organization itself failed in one of its core functions by allowing a preventable infectious disease to spiral out of control in the world’s poorest region. The 68th World Health Assembly (WHA), held in May 2015, provided an opportunity for the Organization to reflect on what went wrong and …

The Normative Authority Of The World Health Organization, Lawrence O. Gostin, Devi Sridhar, Daniel Hougendobler

Georgetown Law Faculty Publications and Other Works

The World Health Organization (WHO) was born after the devastation of World War II, as a normative agency endowed with unprecedented constitutional powers. But even as it has achieved stunning successes, such as the eradication of smallpox, it has failed to live up to the exalted expectations of the postwar health and human rights movement e exemplified most recently by its inadequate response to the Ebola epidemic. Our aim is to offer innovative ideas for restoring the Organization to its leadership position by exercising its normative authority, even as it faces a crowded and often chaotic global health architecture. Before …

Chemical Investigation Of Candidate Probiotics In Aquaculture And Formulation Of A Probiotic Agent For Oyster Larviculure, Christine Anh Dao

Open Access Dissertations

Aquaculture is a multi-billion dollar industry worldwide. The United States is a significant consumer to both fresh and marine aquaculture products. Aquaculture sales in Rhode Island have dramatically increased in the last 20 years. In Rhode Island nearly 4.3 million oysters were produced via aquaculture in 2012. Currently, hatcheries and nurseries in the United States produce large amounts of a variety of species of oysters, clams and scallops. Oysters are filter feeders and are exposed to many microbes in the hatchery. Infectious diseases from bacterial pathogens in the hatcheries can have serious impacts on production. Vibrio species are often responsible …