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2015

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Bears In Pakistan: Distribution, Population Biology And Human Conflicts, Fakhar -I- Abbas, Zahid Iqbal Bhatti, Jibran Haider, Afsar Mian Jun 2015

Bears In Pakistan: Distribution, Population Biology And Human Conflicts, Fakhar -I- Abbas, Zahid Iqbal Bhatti, Jibran Haider, Afsar Mian

Journal of Bioresource Management

We conducted questionnaire based interviews (n = 1873) of respondents coming from 258 localities about bear tracts in northern parts of Pakistan in 2012-2014 to study Himalyan brown (U. arctos isalbellinus) and Himalayan black (U. t. laniger) bears. Brown bears were more frequent in northern latitudes (northern Chitral, Ghizer, Gilgit and Skardu), while black bears were widely distributed in southern latitudes (Battagram). Both brown and black bears are present in central latitudes (Astor, Diamir, Kohistan and Mansehra). We identified 34 populations of brown bears; a large population in the Deosai Plateau and small to very small …

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Foolish Consistencies And The Appellate Review Of Courts-Martial, John F. O'Connor Jun 2015

Foolish Consistencies And The Appellate Review Of Courts-Martial, John F. O'Connor

Akron Law Review

The thesis of this Article is that most of the vices infesting the military appellate system could be corrected, or at least moderated, by reforming the rules governing when, and how, a servicemember can waive his right to appellate review...Part II of this Article examines the “costs” associated with the appeal of a court-martial conviction, that is, the resources that are required to bring a case through its appellate review. When a courtmartial appeal presents colorable issues that the accused has a moral right to raise (not having waived them at trial), these are “costs” that are well worth expending. …

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Helin Data Analytics Task Force Final Report, Helin Consortium. Data Analytics Task Force Jun 2015

Helin Data Analytics Task Force Final Report, Helin Consortium. Data Analytics Task Force

HELIN Task Force reports

The main task undertaken by the HELIN Data Analytics Task Force was to conduct a proof-of-concept usability test of HELIN OneSearch, which is the Consortium’s brand name for the Encore Duet discovery service. After the initial meeting in November 2014, the Task Force met 6 times in 2015 to plan and execute a prototype test. Staff members from EBSCO Information Services’ User Research group acted as usability test advisers and coordinators and attended all meetings, either onsite or via WebEx. Task Force members collaborated to come up with specific scenarios and personas which would best emphasize patron likes, dislikes and …

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Annual Report, 2014-2015, University Of Arkansas, Fayetteville. Office Of The Vice Provost For Research And Economic Development Jun 2015

Annual Report, 2014-2015, University Of Arkansas, Fayetteville. Office Of The Vice Provost For Research And Economic Development

Research and Innovation Annual Report

No abstract provided.

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Human Preferences For Conformation Attributes And Head-And-Neck Positions In Horses, Georgina L. Caspar, Navneet Dhand, Paul Mcgreevy Jun 2015

Human Preferences For Conformation Attributes And Head-And-Neck Positions In Horses, Georgina L. Caspar, Navneet Dhand, Paul Mcgreevy

Competitive Animal Racing Collection

Human preferences for certain morphological attributes among domestic animals may be entirely individual or, more generally, may reflect evolutionary pressures that favor certain conformation. Artificial selection for attributes, such as short heads and crested necks of horses, may have functional and welfare implications because there is evidence from other species that skull shape co-varies with behaviour. Crested necks can be accentuated by flexion of the neck, a quality that is often manipulated in photographs vendors use when selling horses. Equine head-and-neck positions acquired through rein tension can compromise welfare. Our investigation was designed to identify conformations and postures that people …

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Solving Problems, Ensuring Relevance, And Facilitating Change: The Evolution Of Needs Assessment Within Cooperative Extension, Barry A. Garst, Paul F. Mccawley Jun 2015

Solving Problems, Ensuring Relevance, And Facilitating Change: The Evolution Of Needs Assessment Within Cooperative Extension, Barry A. Garst, Paul F. Mccawley

Journal of Human Sciences and Extension

Helping people solve the practical problems of everyday life while maintaining contemporary relevance describes the mission of Cooperative Extension. To achieve that mission, Extension professionals have increasingly relied on information gathered from stakeholders to identify relevant problems and potential educational solutions. The methods, efforts, and activities to understand people and their problems are collectively referred to as needs assessment. This article explores the history and evolution of needs assessment in Cooperative Extension, as well as in a broader educational context. While tracing needs assessment through the decades, this article examines the needs assessment opportunities and challenges faced by Cooperative Extension. …

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Developing Extension Professionals To Develop Extension Programs: A Case Study For The Changing Face Of Extension, Scott R. Cummings, Kevin B. Andrews, Katy M. Weber, Brittney Postert Jun 2015

Developing Extension Professionals To Develop Extension Programs: A Case Study For The Changing Face Of Extension, Scott R. Cummings, Kevin B. Andrews, Katy M. Weber, Brittney Postert

Journal of Human Sciences and Extension

Development of Cooperative Extension programs depends upon the skills and abilities of competent Extension professionals. The most effective manner of building program development competencies in these Extension professionals is through professional development. A wide variety of competencies are necessary for Extension professionals to develop programs, including strong interpersonal skills. Differences exist between the professional development efforts of Extension institutions and are highlighted herein. Major challenges to delivery of professional development include time and budget, but these can be overcome through planning and innovation and use of online or hybrid methods. Professional development for program development is essential to furthering Extension’s …

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Dispute Over The Legality Of Al-Ijarah Al-Mawsufah Fi Al-Dhimah: A Survey Of Fiqhi Opinions, M.M. Abu Talib, A.A. Akhtarzaite Jun 2015

Dispute Over The Legality Of Al-Ijarah Al-Mawsufah Fi Al-Dhimah: A Survey Of Fiqhi Opinions, M.M. Abu Talib, A.A. Akhtarzaite

Research Publications (2011 to 2015)

The legality of al-ijārah al-mawṣūfah fī al-dhimmah (AIMAD) has been disputed. Some contemporary scholars have mentioned disagreement among the early Muslim scholars about it and have identified the Ḥanafī School’s position to be prohibition. In fact, the classical texts of most juristic schools are similar in terms of the discussion on this contract. Hence, the question that arises is whether there is really a dispute among the four major Sunni schools of Islamic law or consensus on the legality of AIMAD. In order to answer the question, this paper discusses the classical and contemporary fiqh literature on this issue. The …

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Southern Track And Pump Inc V. Terex Corp Jun 2015

Southern Track And Pump Inc V. Terex Corp

2015 Decisions

USDC for the District of Delaware

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Method, Composition, And Kit Useful For Treatment Of Alzheimer's Disease, Steven Estus, Manasi Malik, James Simpson Jun 2015

Method, Composition, And Kit Useful For Treatment Of Alzheimer's Disease, Steven Estus, Manasi Malik, James Simpson

Biology Faculty Patents

The presently-disclosed subject matter includes methods for treating Alzheimer's disease in a subject. The subject can have Alzheimer's diseases, can be identified has being at risk for developing Alzheimer's disease, or both. The method can comprise administering a composition that includes a CD33 inhibitor, which may include a CD33 antibody. In some embodiments the composition can further comprise at least one additional component useful for treating Alzheimer's disease. The presently-disclosed subject matter also includes compositions and kits for treating Alzheimer's disease in a subject.

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A Milk And Ochre Paint Mixture Used 49,000 Years Ago At Sibudu, South Africa, Paola Villa, Luca Pollarolo, Ilaria Degano Jun 2015

A Milk And Ochre Paint Mixture Used 49,000 Years Ago At Sibudu, South Africa, Paola Villa, Luca Pollarolo, Ilaria Degano

KIP Articles

Gas chromatography/mass spectrometry, proteomic and scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM/EDS) analyses of residue on a stone flake from a 49,000 year-old layer of Sibudu (South Africa) indicate a mixture of ochre and casein from milk, likely obtained by killing a lactating wild bovid. Ochre powder production and use are documented in Middle Stone Age South African sites but until now there has been no evidence of the use of milk as a binder. Our analyses show that this ochre-based mixture was neither a hafting adhesive nor a residue left after treating animal skins, but a liquid mixture …

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Nnb News, In A Once-Gritty Industrial Area, They Create Art, June 30, 2015, Phil Lavery Jun 2015

Nnb News, In A Once-Gritty Industrial Area, They Create Art, June 30, 2015, Phil Lavery

Neighborhood News Bureau

A spotlight on Five Deuces Galleria in the historically Black neighborhood of St. Petersburg "The Deuces."

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Coupling Between Cytoplasmic Concentration Gradients Through Local Control Of Protein Mobility In The Caenorhabditis Elegans Zygote, Youjun Wu, Huaiying Zhang, Erik E. Griffin Jun 2015

Coupling Between Cytoplasmic Concentration Gradients Through Local Control Of Protein Mobility In The Caenorhabditis Elegans Zygote, Youjun Wu, Huaiying Zhang, Erik E. Griffin

Dartmouth Scholarship

Cell polarity is characterized by the asymmetric distribution of factors at the cell cortex and in the cytoplasm. Although mechanisms that establish cortical asymmetries have been characterized, less is known about how persistent cytoplasmic asymmetries are generated. During the asymmetric division of the Caenorhabditis elegans zygote, the PAR proteins orchestrate the segregation of the cytoplasmic RNA-binding proteins MEX-5/6 to the anterior cytoplasm and PIE-1, POS-1, and MEX-1 to the posterior cytoplasm. In this study, we find that MEX-5/6 control the segregation of GFP::PIE-1, GFP::POS-1, and GFP::MEX-1 by locally increasing their mobility in the anterior cytoplasm. Remarkably, PIE-1, POS-1, and MEX-1 …

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Full Issue, Iajbs Ateneo De Manila University Jun 2015

Full Issue, Iajbs Ateneo De Manila University

Journal of Management for Global Sustainability

No abstract provided.

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Unraveling The Mysteries Of The Mitochondria In Huntington's Disease – And Getting Fast, Clear, And Useful Results From Research Studies, Kenneth P. Serbin Jun 2015

Unraveling The Mysteries Of The Mitochondria In Huntington's Disease – And Getting Fast, Clear, And Useful Results From Research Studies, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

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2014-2015 Department Of Biomedical Sciences Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University Jun 2015

2014-2015 Department Of Biomedical Sciences Scholarly Activity Report, Quillen College Of Medicine, East Tennessee State University

Quillen College of Medicine Scholarly Activity Reports

No abstract provided.

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Onset Time And Durability Of Huntingtin Suppression In Rhesus Putamen After Direct Infusion Of Antihuntingtin Sirna, Richard Grondin, Pei Ge, Qingmin Chen, Jessica E. Sutherland, Zhiming Zhang, Don M. Gash, David K. Stiles, Gregory R. Stewart, Dinah W. Y. Sah, William F. Kaemmerer Jun 2015

Onset Time And Durability Of Huntingtin Suppression In Rhesus Putamen After Direct Infusion Of Antihuntingtin Sirna, Richard Grondin, Pei Ge, Qingmin Chen, Jessica E. Sutherland, Zhiming Zhang, Don M. Gash, David K. Stiles, Gregory R. Stewart, Dinah W. Y. Sah, William F. Kaemmerer

Neuroscience Faculty Publications

One possible treatment for Huntington's disease involves direct infusion of a small, interfering RNA (siRNA) designed to reduce huntingtin expression into brain tissue from a chronically implanted programmable pump. Here, we studied the suppression of huntingtin mRNA achievable with short infusion times, and investigated how long suppression may persist after infusion ceases. Rhesus monkeys received 3 days of infusion of Magnevist into the putamen to confirm catheter patency and fluid distribution. After a 1-week washout period, monkeys received radiolabeled siRNA targeting huntingtin. After 1 or 3 days of siRNA delivery, monkeys were either terminated, or their pumps were shut off …

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Applying The Case-Based Method In Designing Self-Directed Online Instruction, Heng Luo Jun 2015

Applying The Case-Based Method In Designing Self-Directed Online Instruction, Heng Luo

Dissertations - ALL

No abstract provided.

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The Impact Of The Use Of Auxiliary Tools In The Development Of Some Special Physical Qualities And The Level Of Achievement In The High Jump In The Fosbury Method, Luqman Saleh Karim, Ibtisam Haidar Bektash Jun 2015

The Impact Of The Use Of Auxiliary Tools In The Development Of Some Special Physical Qualities And The Level Of Achievement In The High Jump In The Fosbury Method, Luqman Saleh Karim, Ibtisam Haidar Bektash

Modern Sport

This study aimed to investigate the effect of using auxiliary tools on developing specific physical attributes and improving performance in the high jump using the Fosbury technique. The researchers employed the experimental method with a comparative approach, suitable for the nature of the study. The research sample consisted of 40 first-year students selected from a total of 100, divided into four sections (A, B, C, D). The control group followed the traditional training method, while the experimental group used auxiliary tools and a device designed by the researchers, including Swiss balls, a moving pulley, and inverted hurdles. Data collection tools …

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Analisis Dampak Kesalahan Konsep Laju Reaksi Terhadap Kesalahan Konsep Kesetimbangan Pada Siswa Sma, Yeyek Ihdal Umam, Srini M. Iskandar, Endang Budiasih Jun 2015

Analisis Dampak Kesalahan Konsep Laju Reaksi Terhadap Kesalahan Konsep Kesetimbangan Pada Siswa Sma, Yeyek Ihdal Umam, Srini M. Iskandar, Endang Budiasih

Jurnal Pendidikan Sains

This study was designed to analyze the misconception of the chemistry subject reaction rate and chemical equilibrium and the effect of the misconceptions on the chemical equilibrium con-cept. The subjects of the research are two homogenous classes from seven science classes which were determined using random sampling technique. The research instruments were multiple choice test with four answers as well as an interview. The result showed that misconception occurred in all concepts discussed in this research and the impact of the misconception on chemical equilibrium concept occured in reaction rate concept and effect of increasing concentration of the reaction rate …

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Perbandingan Kemandirian Belajar Teknik Animasi 2d Pada Penerapan Tiga Model Pembelajaran Terhadap Siswa Smk, Elsa Dwi Rochmah Rachmanto, Setiadi Cahyono Putro, Utomo Pujianto Jun 2015

Perbandingan Kemandirian Belajar Teknik Animasi 2d Pada Penerapan Tiga Model Pembelajaran Terhadap Siswa Smk, Elsa Dwi Rochmah Rachmanto, Setiadi Cahyono Putro, Utomo Pujianto

Jurnal Pendidikan Sains

Based on observation, it was discovered that the learning process of 2D-Animation Tech-nique in SMK Multimedia Tumpang still used teacher-centered method that caused some students did not improve their learning independence. The offered solution was implementing various construc-tivists learning models covering Problem Based Learning (PBL), Project Based Learning (PjBL) and Discovery Learning (DL). This study aimed at knowing variance of students’ learning independence means of implementing these three models. This study employed Posttest-Only Control Design with One-Way ANOVA and Post-Hoc testing. Concisely, there was significant variance of students’ learning independence means of using PBL, PjBL and DL learning models.

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Eph-Ephrin Signaling And The Role Of Efn-4 In Caenorhabditis Elegans Nervous Systems Development, Alicia Schwieterman Jun 2015

Eph-Ephrin Signaling And The Role Of Efn-4 In Caenorhabditis Elegans Nervous Systems Development, Alicia Schwieterman

Master of Science in Integrative Biology Theses

Eph receptor tyrosine kinases and their ephrin ligands are required for multiple aspects of nervous system development including axon outgrowth, synaptic plasticity, and the formation of topographic maps in the visual system. The Caenorhabditis elegans ephrin-A, efn-4, has a defined role in hypodermal patterning but its role in nervous system development is not well understood. We find that loss-of-function mutations in efn-4 lead to suppression of axon branching in C. elegans model of X-linked Kallmann syndrome, a human genetic disorder that presents with loss of sense of smell and failure to undergo spontaneous puberty. In addition, efn-4 mutants have …

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Ecological Worldviews: A Missing Perspective To Advance Global Sustainability Leadership, Steve Schein Jun 2015

Ecological Worldviews: A Missing Perspective To Advance Global Sustainability Leadership, Steve Schein

Journal of Management for Global Sustainability

Since the corporate sustainability movement emerged more than 20 years ago, much has been written about how multinational corporations must play an important role in solving the planet’s ecological challenges. However, while corporate sustainability research has focused extensively on environmental impacts, strategies, and best practices at the organizational level, not enough attention has been paid to sustainability leadership at the individual level. As a result, little is known about the psychological motivations of corporate sustainability executives and how this may relate to their behavior as change agents. Based on insights from social science disciplines, including ecopsychology, integral ecology, and developmental …

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Managing For Resilience: Lessons From Ecology, Nancy E. Landrum, Ray Dybzinski, , Amina Smajlovic, Brian M. Ohsowski Jun 2015

Managing For Resilience: Lessons From Ecology, Nancy E. Landrum, Ray Dybzinski, , Amina Smajlovic, Brian M. Ohsowski

Journal of Management for Global Sustainability

Understanding and developing resilience is becoming increasingly important in business for both leaders and organizations. Resilient organizations can successfully navigate uncertainty and change. Resilience, however, is a poorly understood attribute. We thus turn to ecosystem resilience theory to understand the concept of resilience. We identify four lessons that can be adapted from management for ecological resilience to management for business resilience: 1) resilience can be positive or negative depending on the nature of the function it supports, 2) diversity of individuals, departments, flows of information, perspective, and other attributes contributes to resilience, 3) because we have imperfect knowledge about the …

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Biological Activity Of Recently Discovered Halogenated Marine Natural Products, Gordon Gribble Jun 2015

Biological Activity Of Recently Discovered Halogenated Marine Natural Products, Gordon Gribble

Dartmouth Scholarship

This review presents the biological activity—antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity—of halogenated marine natural products discovered in the past five years. Newly discovered examples that do not report biological activity are not included.

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A Structural And Functional Comparison Between Infectious And Non-Infectious Autocatalytic Recombinant Prp Conformers, Geoffrey P. Noble, Daphne W. Wang, Daniel J. Walsh, Justin R. Barone, Michael B. Miller, Koren A. Nishina, Sheng Li, Surachai Supattapone Jun 2015

A Structural And Functional Comparison Between Infectious And Non-Infectious Autocatalytic Recombinant Prp Conformers, Geoffrey P. Noble, Daphne W. Wang, Daniel J. Walsh, Justin R. Barone, Michael B. Miller, Koren A. Nishina, Sheng Li, Surachai Supattapone

Dartmouth Scholarship

Infectious prions contain a self-propagating, misfolded conformer of the prion protein termed PrPSc. A critical prediction of the protein-only hypothesis is that autocatalytic PrPSc molecules should be infectious. However, some autocatalytic recombinant PrPSc molecules have low or undetectable levels of specific infectivity in bioassays, and the essential determinants of recombinant prion infectivity remain obscure. To identify structural and functional features specifically associated with infectivity, we compared the properties of two autocatalytic recombinant PrP conformers derived from the same original template, which differ by >105-fold in specific infectivity for wild-type mice. Structurally, hydrogen/deuterium exchange mass spectrometry (DXMS) studies revealed that solvent …

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Selective Impact Of Cdk4/6 Suppression On Patient-Derived Models Of Pancreatic Cancer., Agnieszka K Witkiewicz, Nicholas A Borja, Jorge Franco, Jonathan Brody, Md, Charles Yeo, John Mansour, Michael A Choti, Peter Mccue, Erik S Knudsen Jun 2015

Selective Impact Of Cdk4/6 Suppression On Patient-Derived Models Of Pancreatic Cancer., Agnieszka K Witkiewicz, Nicholas A Borja, Jorge Franco, Jonathan Brody, Md, Charles Yeo, John Mansour, Michael A Choti, Peter Mccue, Erik S Knudsen

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Pancreatic ductal adenocarcinoma (PDA) harbors an exceedingly poor prognosis, and is generally considered a therapy-recalcitrant disease due to poor response to conventional chemotherapy coupled with non-actionable genetic drivers (e.g. KRAS mutations). However, PDA frequently loses p16ink4a, thereby leading to deregulation of CDK4/6. Surprisingly, in established cell models and xenografts, CDK4/6 inhibition has a modest effect on proliferation and resistance develops rapidly. To determine if such weak response was an intrinsic feature of PDA, we developed primary tumor explants that maintain the tumor environment and recapitulate feuture of primary PDA. The CDK4/6 inhibitor PD-0332991 was highly efficient at suppressing proliferation in …

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Novel Cross Talk Between Igf-Ir And Ddr1 Regulates Igf-Ir Trafficking, Signaling And Biological Responses., Roberta Malaguarnera, Maria Luisa Nicolosi, Antonella Sacco, Alaide Morcavallo, Veronica Vella, Concetta Voci, Michela Spatuzza, Shi-Qiong Xu, Renato V Iozzo, Riccardo Vigneri, Andrea Morrione, Antonino Belfiore Jun 2015

Novel Cross Talk Between Igf-Ir And Ddr1 Regulates Igf-Ir Trafficking, Signaling And Biological Responses., Roberta Malaguarnera, Maria Luisa Nicolosi, Antonella Sacco, Alaide Morcavallo, Veronica Vella, Concetta Voci, Michela Spatuzza, Shi-Qiong Xu, Renato V Iozzo, Riccardo Vigneri, Andrea Morrione, Antonino Belfiore

Kimmel Cancer Center Faculty Papers

The insulin-like growth factor-I receptor (IGF-IR), plays a key role in regulating mammalian development and growth, and is frequently deregulated in cancer contributing to tumor initiation and progression. Discoidin domain receptor 1 (DDR1), a collagen receptor tyrosine-kinase, is as well frequently overexpressed in cancer and implicated in cancer progression. Thus, we investigated whether a functional cross-talk between the IGF-IR and DDR1 exists and plays any role in cancer progression.Using human breast cancer cells we found that DDR1 constitutively associated with the IGF-IR. However, this interaction was enhanced by IGF-I stimulation, which promoted rapid DDR1 tyrosine-phosphorylation and co-internalization with the IGF-IR. …

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Religious Experiences Of Filipino Catholic Women Migrants In Japan: The Case Of The Kaagapay Oita Filipino Association, Melvin A. Jabar Jun 2015

Religious Experiences Of Filipino Catholic Women Migrants In Japan: The Case Of The Kaagapay Oita Filipino Association, Melvin A. Jabar

Asia-Pacific Social Science Review

No abstract provided.

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Southern Free Women Of Color In The Antebellum North: Race, Class, And A "New Women's Legal History", Bernie D. Jones Jun 2015

Southern Free Women Of Color In The Antebellum North: Race, Class, And A "New Women's Legal History", Bernie D. Jones

Akron Law Review

This article develops Welke’s theme and proposes that in the field of legal history, the analyses can not be limited to “race, gender, or class,” but that matrices of race, gender, and class must be considered at their intersections, “race, and gender, and class,” where they might shed light on the significance of shifting legal modalities. It explores how race, gender, and class as legal policy in the 19th century could be crucial for the formation of family and marital relationships in the private sphere. The focus here is upon free women of color living in the antebellum North who …

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