Digital Commons Network^™

Beware — The Holy Spirit! Part 2, Anthony Gittins

Spiritan Magazine

No abstract provided.

Healthy You Hazleton, Lehigh Valley Health Network

Healthy You

No abstract provided.

Effect Of A Mindfulness Intervention On Stress And Coping Strategies In Physician Assistant Students, Mark Volpe

Yale School of Medicine Physician Associate Program Theses

Physician assistant students represent a stressed population, often with poor coping skills. Prior research amongst undergraduate and graduate students has shown that mindfulness interventions are often effective in reducing stress in the short-term. This has not been studied in physician assistant students or for long-term outcomes. We propose a randomized controlled trial to study the effects of a mindfulness intervention on short-term and long-term physician assistant student stress and coping skills. Students from three sites in Connecticut will be provided an eight week mindfulness intervention or be placed in a control group. Stress and coping skills will be measured at …

Alumni Notes

Maryland Carey Law

No abstract provided.

Global Borderlands: A Case Study Of Subic Bay Freeport Zone, Philippines, Victoria Reyes

Growth and Structure of Cities Faculty Research and Scholarship

By developing the concept of “global borderlands”–semi-autonomous, foreign-controlled geographic locations geared toward international exchange–this article shifts the focus of globalization literature from elite global cities and cities on national borders to within-country sites owned and/or operated by foreigners and defined by significant social, cultural, and economic exchange. I analyze three shared features of these sites: semi-autonomy, symbolic and geographic boundaries, and unequal relations. The multi-method analyses reveal how the concept of global borderlands can help us better understand the interactions that occur in the contemporary era of globalization across people of different nationalities, classes, and races/ethnicities as well as the …

The Greenbook, Faculty Handbook, 2015-2016, Marshall University Academic Affairs

The Greenbook

This book has been published for the faculty of Marshall University for the specified period of time. This book was created by what is now known as Academic Affairs and is for the period of 2015-2016.

Marshall Magazine Summer 2015, Marshall University

Marshall Magazine

No abstract provided.

Targeting Il13ralpha2 Activates Stat6-Tp63 Pathway To Suppress Breast Cancer Lung Metastasis, Panagiotis Papageorgis, Sait Ozturk, Arthur W. Lambert, Christiana M. Neophytou, Alexandros Tzatsos, Chen K. Wong, Sam Thiagalingam, Andreas I. Constantinou

Anatomy and Regenerative Biology Faculty Publications

Introduction

Basal-like breast cancer (BLBC) is an aggressive subtype often characterized by distant metastasis, poor patient prognosis, and limited treatment options. Therefore, the discovery of alternative targets to restrain its metastatic potential is urgently needed. In this study, we aimed to identify novel genes that drive metastasis of BLBC and to elucidate the underlying mechanisms of action.

Methods

An unbiased approach using gene expression profiling of a BLBC progression model and in silicoleveraging of pre-existing tumor transcriptomes were used to uncover metastasis-promoting genes. Lentiviral-mediated knockdown of interleukin-13 receptor alpha 2 (IL13Ralpha2) coupled with whole-body in vivo bioluminescence imaging was …

Intermingled Klebsiella Pneumoniae Populations Between Retail Meats And Human Urinary Tract Infections, Gregg S. Davis, Kara Waits, Lora Nordstrom, Brett Weaver, Maliha Aziz, Lance B. Price, +8 Additional Authors

Environmental and Occupational Health Faculty Publications

Background. Klebsiella pneumoniae is a common colonizer of the gastrointestinal tract of humans, companion animals, and livestock. To better understand potential contributions of foodborne K. pneumoniae to human clinical infections, we compared K. pneumoniae isolates from retail meat products and human clinical specimens to assess their similarity based on antibiotic resistance, genetic relatedness, and virulence.

Methods. Klebsiella pneumoniae was isolated from retail meats from Flagstaff grocery stores in 2012 and from urine and blood specimens from Flagstaff Medical Center in 2011–2012. Isolates underwent antibiotic susceptibility testing and whole-genome sequencing. Genetic relatedness of the isolates was assessed using multilocus sequence typing …

Myasthenia Gravis, Abbe R. Feaver

Nursing Student Class Projects (Formerly MSN)

Myasthenia gravis (MG) is a chronic autoimmune neuromuscular disease characterized by ocular, bulbar, facial, and skeletal muscle weakness due to a defect in the transmission of nerve to muscle impulses at the neuromuscular junction (Mestecky, 2013, p. 110). Approximately 14-20 in 100,000 people are diagnosed with myasthenia gravis in the United States (Leis, Moore, Kofler, Beric, De Visser, 2014, p. 112). Typically, diagnosis occurs in middle-aged adults with women generally acquiring the disease at a younger age than men (Mestecky, 2013, p. 110). MG has the potential to greatly affect the quality of life of a patient. Although the disease …

Neurocysticercosis, Abigail Hill

Nursing Student Class Projects (Formerly MSN)

Neurocysticercosis (NCC) is one of the most common parasitic infections of the central nervous system in humans and is the most serious clinical manifestation of cysticercosis. NCC is caused by the ingestion of the larval form of the pork tapeworm Taenia solium. NCC is endemic in low income developing countries where pigs are commonly raised, including the countries of Central America, South America, and parts of Africa and Asia. (Naddaf, Seeger, & Stafstrom, 2014). The parasite Taenia solium encysts in the brain and can express a broad range of symptoms including seizures, headache, hydrocephalus, encephalitis, stroke and mental health and …

The Institute Of Archaeology & Siegfried H. Horn Museum Newsletter Volume [36.3], Dorian Alexander, Constance Gane

Institute of Archaeology & the Horn Archaeological Museum Newsletter

Schultz Lecture, Dorian Alexander

SHHM Outreach, Constance E. Gane

Random Survey

Estradiol Preferentially Induces Progestin Receptor-A (Pr-A) Over Pr-B In Cells Expressing Nuclear Receptor Coactivators In The Female Mouse Hypothalamus, Kalpana D. Acharya, Sarah D. Finkelstein, Elizabeth P. Bless, Sabin A. Nettles, Biserka Mulac-Jericevic, Orla M. Conneely, Shaila K. Mani, Marc J. Tetel

Faculty Research and Scholarship

Estrogens act in brain to profoundly influence neurogenesis, sexual differentiation, neuroprotection, cognition, energy homeostasis, and female reproductive behavior and physiology through a variety of mechanisms, including the induction of progestin receptors (PRs). PRs are expressed as two isoforms, PR-A and PR-B, that have distinct functions in physiology and behavior. Because these PR isoforms cannot be distinguished using cellular resolution techniques, the present study used isoform-specific null mutant mice that lack PR-A or PR-B for the first time to investigate whether 17β-estradiol benzoate (EB) regulates the differential expression of the PR isoforms in the ventromedial nucleus of the hypothalamus (VMN), arcuate …

Wellesley Magazine Summer 2015, Wellesley College Alumnae Association

Wellesley Magazine (Alumnae Association)

Featured in this issue:

Dear Me, Letters from Eight Alumnae

Making Things, Making a Difference / by Lisa Scanlon Mogolov ’99

A Gathering of Flowers / by Catherine O’Neill Grace

Hexapod Herald - Vol. 27, No. 3, July 2015

Hexapod Herald and Other Entomology Department Newsletters

Content: Welcome - Faculty Changes - Meeting News - Grants - Publications - Student News - Calendar of Events - Meet an Off-Campus Student - Bee Blitz - Fond Farewells - Travel - Congratulations - Blast from the Past - AEM (Agriculture Hall, Entomology Hall, and Miller Hall) Business Center Changes

Topbp1 Governs Hematopoietic Stem/Progenitor Cells Survival In Zebrafish Definitive Hematopoiesis., Lei Gao, Dantong Li, Ke Ma, Wenjuan Zhang, Tao Xu, Wenge Zhu, +12 Additional Authors

Biochemistry and Molecular Medicine Faculty Publications

In vertebrate definitive hematopoiesis, nascent hematopoietic stem/progenitor cells (HSPCs) migrate to and reside in proliferative hematopoietic microenvironment for transitory expansion. In this process, well-established DNA damage response pathways are vital to resolve the replication stress, which is deleterious for genome stability and cell survival. However, the detailed mechanism on the response and repair of the replication stress-induced DNA damage during hematopoietic progenitor expansion remains elusive. Here we report that a novel zebrafish mutantcas003 with nonsense mutation in topbp1 gene encoding topoisomerase II β binding protein 1 (TopBP1) exhibits severe definitive hematopoiesis failure. Homozygous topbp1cas003 mutants manifest reduced number of HSPCs …

Chagas Disease: Immigrating Into The United States, Angela Metzger

Nursing Student Class Projects (Formerly MSN)

Chagas Disease is starting to make a profound entrance into our communities within the United States. The influx of the immigrant population is the principal cause of the accumulation in the number of reported cases. (Center for Disease Control and Prevention, 2014). The Trypanosoma cruzi is a parasite that causes Chagas disease. The triatomine blood sucking insect enjoys the mucosal membranes of their pray, both humans and animals. The most common regions of the penetrating bite are the conjunctiva of the eye or around the mouth. It is through the feces of the vector entering the inoculation site that initiates …

Exploring The Pathophysiological Concepts Of Ebola Virus, Andrew T. Wasson

Nursing Student Class Projects (Formerly MSN)

The Ebola virus is a member of the filoviridae family. Five distinctive species of ebolavirus have been identified, four of which are known to cause disease in humans (Martines, Ng, Greer, Rollin, and Zaki, 2014). The specific species known to cause disease in humans are Zaire, Sudan, Ivory Coast, and Bundibugyo (Bray & Chertow, 2014). Bah et al. (2015) report that the Zaire ebolavirus (EBOV) was the cause of the most recent West African outbreak and carries the highest human mortality rate among the five known species, with up to 90% of cases being fatal. Ebola is a filamentous, enveloped, …

Lawrence, Volume 96, Number 2, Summer 2015, Lawrence University

Alumni Magazines

No abstract provided.

Annual Report, 2015, University Of Arkansas, Fayetteville. J. William Fulbright College Of Arts And Sciences. King Fahd Center For Middle East Studies

King Fahd Center for Middle East & Islamic Studies Annual Report

Program Director: Tom Paradise, 2005-2009; Joel Gordon, 2009-

On The Principle Of Competitive Exclusion In Metapopulation Models, Davide Belocchio, Roberto Cavoretto, Giacomo Gimmelli, Alessandro Marchino, Ezio Venturino

Applied Mathematics & Information Sciences

In this paper we present and analyse a simple two populations model with migrations among two different environments. The populations interact by competing for resources. Equilibria are investigated. A proof for the boundedness of the populations is provided. A kind of competitive exclusion principle for metapopulation systems is obtained. At the same time we show that the competitive exclusion principle at the local patch level may be prevented to hold by the migration phenomenon, i.e. two competing populations may coexist, provided that only one of them is allowed to freely move or that migrations for both occur just in one …

Renewing Electricity Competition, David Schraub

Florida State University Law Review

The scholarly literature on law and social movement has historically focused on public law issues like environmentalism, reproductive rights, and race relations, while staying far away from business and firm behavior. Business behavior was easily understood as that of self-interested profit-maximizers and thereby left to the economics. Recently, however, social movement theorists have begun paying more attention to the business world. While traditional economic models can explain why businesses pursue higher profits, greater market shares, and superior regulatory climates, they are limited in their ability to explain how wish becomes reality. The formation and identification of market opportunities are products …

Seagrassnet Manual For Scientific Monitoring Of Seagrass Habitat, Frederick T. Short, Robert G. Coles, Catherine M. Short

PREP Reports & Publications

No abstract provided.

Macalester Today Summer 2015, Macalester College

Macalester Today

No abstract provided.

The Production Of Alpha/Beta And Gamma/Delta Double Negative (Dn) T-Cells And Their Role In The Maintenance Of Pregnancy, John C. Chapman, Fae M. Chapman, Sandra D. Michael

Biological Sciences Faculty Scholarship

The ability of the thymus gland to convert bone marrow-derived progenitor cells into single positive (SP) T-cells is well known. In this review we present evidence that the thymus, in addition to producing SP T-cells, also has a pathway for the production of double negative (DN) T-cells. The existence of this pathway was noted during our examination of relevant literature to determine the cause of sex steroid-induced thymocyte loss. In conducting this search our objective was to answer the question of whether thymocyte loss is the end product of a typical interaction between the reproductive and immune systems, or evidence …

Soluble Epoxide Hydrolase Null Mice Exhibit Female And Male Differences In Regulation Of Vascular Homeostasis, Luca Vanella, Martina Canestraro, Craig R. Lee, Jian Cao, Darryl C. Zeldin, Michal L. Schwartzman, Nader G. Abraham

NYMC Faculty Publications

Increased CYP epoxygenase activity and consequently up regulation of epoxyeicosatrienoic acids (EETs) levels provides protection against metabolic syndrome and cardiovascular diseases. Conversion of arachidonic acid epoxides to diols by soluble epoxide hydrolase (sEH) diminishes the beneficial cardiovascular properties of these epoxyeicosanoids. We therefore examined the possible biochemical consequences of sEH deletion on vascular responses in male and female mice. Through the use of the sEH KO mouse, we provide evidence of differences in the compensatory response in the balance between nitric oxide (NO), carbon monoxide (CO), EETs and the vasoconstrictor 20-HETE in male and female KO mice. Serum levels of …

Telonicher Marine Laboratory, Hsu Telonicher Marine Laboratory

Newsletters

No abstract provided.

Wsu Research News, Summer 2015, Office Of Research And Sponsored Programs, Wright State University

WSU Research News

A sixteen page newsletter of the WSU Research News. The WSU Research News was published monthly beginning in June of 1968 and issued by the Office of Research Development. This newsletter was created to provide information to the WSU faculty about the availability of outside funds for research and educational programs, new developments that may affect availability of funds, and general information on research and educational activities at Wright State University.

The Journal Of Erw And Mine Action Issue 19.1 (2015), Cisr Journal

The Journal of Conventional Weapons Destruction

Focus on Vietnam

Feature: Cultural and Environmental Issues in Demining

Notes from the Field

Research and Development

Mine Action In Myanmar, Roger Fasth, Pascal Simon

The Journal of Conventional Weapons Destruction

In two Myanmar states, Danish Demining Group and Danish Refugee Council recently conducted a landmine victims survey that helped to document the epidemiology of landmine accidents and the situation of landmine victims more efficiently as well as recommend improved services to landmine survivors and persons with disabilities.