Novel Targeted Sirna-Loaded Hybrid Nanoparticles: Preparation, Characterization And In Vitro Evaluation., Nneka Dim, Maryna Perepelyuk, Olukayode Gomes, Chellappagounder Thangavel, Yi Liu, Robert Den, Ashakumary Lakshmikuttyamma, Sunday A Shoyele

Department of Radiation Oncology Faculty Papers

BACKGROUND: siRNAs have a high potential for silencing critical molecular pathways that are pathogenic. Nevertheless, their clinical application has been limited by a lack of effective and safe nanotechnology-based delivery system that allows a controlled and safe transfection to cytosol of targeted cells without the associated adverse effects. Our group recently reported a very effective and safe hybrid nanoparticle delivery system composing human IgG and poloxamer-188 for siRNA delivery to cancer cells. However, these nanoparticles need to be optimized in terms of particle size, loading capacity and encapsulation efficiency. In the present study, we explored the effects of certain production …

Determination And Evaluation Of Element Bioaccessibility In Some Nuts And Seeds By In-Vitro Gastro-Intestinal Method, Burcu Kafaoglu, Andrew Fisher, Steve Hill, Derya Kara

School of Geography, Earth and Environmental Sciences

Element bioaccessibility in some nuts and seeds has been determined by performing a physiologically based extraction test. Nine elements (B, Ca, Co, Cu, Fe, Mn, Mg, Ni and Zn) in gastric and intestinal phase extractions of nuts and seeds were determined using inductively coupled plasma-atomic emission spectrometry and inductively coupled plasma-mass spectrometry. Hazelnuts, almonds, sunflower seeds, peanuts, cashew nuts, Brazil nuts, walnuts, chickpeas, pumpkin seeds and pistachio nuts were used as the materials in this study. The bioaccessible portions of magnesium and calcium were higher than for the other elements whereas B bioaccessibility was the lowest for each of the …

Testing And Templates: Building Effective Research Guides, Patricia Gimenez, Stephanie Grimm, Katy Parker

Georgia International Conference on Information Literacy

The Savannah College of Art and Design has nearly 12,000 students at 5 separate campus locations, and offers more than 40 areas of concentration within art and design. The students are incredibly career-minded, and class assignments are built to mimic the professional experience. Through the SCAD Libraries, students have access to nearly 90 databases, many of which are professional level resources, and hundreds of trade and scholarly print journals. Using Spring Share's LibGuides, the small research and instruction team has created a series of course and subject specific research guides to highlight the professional databases and teach valuable information literacy …

Assessing The Effectiveness Of A Pre-Class Intervention In Establishing An Information Literacy Baseline, Adelia B. Grabowsky

Georgia International Conference on Information Literacy

It is expected that undergraduates entering a BSN clinical program as juniors will possess basic information literacy skills. The reality is that skills vary widely, complicating efforts to provide more advanced, discipline-specific instruction. The purpose of this study is to evaluate the effectiveness of a pre-class intervention intended to establish an information literacy baseline in newly admitted nursing students. Setting/Participants: Nursing students in the first clinical semester of a BSN program at a large, southeastern, research university. Intervention: Before attending a library instruction class, students watch a short video and complete a worksheet which they bring to class. Outcome Measures: …

Semiotics: Putting Theory Into Practice, Rudy Barrett

Lexia: Undergraduate Journal in Writing, Rhetoric & Technical Communication

Rudy Barrett applies theories of semiotics to create a graphic organizer to track his daily and weekly schedule.

Comida Colombiana, Carly Botero

Lexia: Undergraduate Journal in Writing, Rhetoric & Technical Communication

Carly Botero reminisces about the delicate foods that link her to her familial homeland, Colombia.

Modulation Of Locomotion And Reproduction By Flp Neuropeptides In The Nematode Caenorhabditis Elegans, Yan-Jung Chang, Tina Burton, Lawrence Ha, Zi Huang, Adewale Olajubelo, Chris Li

Publications and Research

Neuropeptides function in animals to modulate most, if not all, complex behaviors. In invertebrates, neuropeptides can function as the primary neurotransmitter of a neuron, but more generally they co-localize with a small molecule neurotransmitter, as is commonly seen in vertebrates. Because a single neuron can express multiple neuropeptides and because neuropeptides can bind to multiple G protein-coupled receptors, neuropeptide actions increase the complexity by which the neural connectome can be activated or inhibited. Humans are estimated to have 90 plus neuropeptide genes; by contrast, nematodes, a relatively simple organism, have a slightly larger complement of neuropeptide genes. For instance, the …

South Africa's Agricultural Sector Twenty Years After Democracy (1994 To 2013), Jan C. Greyling, Nick Vink, Edward Mabaya

Professional Agricultural Workers Journal

Abstract

South Africa’s agricultural sector has undergone substantial policy reform since the dawn of democracy in 1994. Now, twenty years later, it is an opportune time to look back at this period to review key successes and failures. This article revisits South Africa’s context and policy at the start of this period, the reforms that followed, and evaluates the transformational effect (or lack thereof) on the sector. For this purpose, the article pulls from both qualitative sources and descriptive statistics to provide both a historical context and current perspective. The analysis shows that redistributive land reform and smallholder support programs …

Lipin1 Regulates Skeletal Muscle Differentiation Through Extracellular Signal-Regulated Kinase (Erk) Activation And Cyclin D Complex-Regulated Cell Cycle Withdrawal, Weihua Jiang, Jing Zhu, Xun Zhuang, Xiping Zhang, Tao Luo, Karyn Esser, Hongmei Ren

Saha Cardiovascular Research Center Faculty Publications

Lipin1, an intracellular protein, plays critical roles in controlling lipid synthesis and energy metabolism through its enzymatic activity and nuclear transcriptional functions. Several mouse models of skeletal muscle wasting are associated with lipin1 mutation or altered expression. Recent human studies have suggested that children with homozygous null mutations in the LPIN1 gene suffer from rhabdomyolysis. However, the underlying pathophysiologic mechanism is still poorly understood. In the present study we examined whether lipin1 contributes to regulating muscle regeneration. We characterized the time course of skeletal muscle regeneration in lipin1-deficient fld mice after injury. We found that fld mice exhibited smaller regenerated …

September 25, 2015, The Dakota Student

The Dakota Student

No abstract provided.

The Real Cost Of Going Clean: The Potential Impact Of South Africa's 2016 Carbon Tax On Agricultural Production, Andrew Partridge, Leanne Cloete-Beets, Vanessa Barends

Professional Agricultural Workers Journal

No abstract provided.

An Analysis Of The Characteristics And Practices Of Selected Alabama Small Livestock Producers: A Focus On Economics And Marketing, Jannette R. Bartlett, Nii O. Tackie, Mst Nusrat Jahan, Akua Adu-Gyamfi

Professional Agricultural Workers Journal

Abstract

The study examined the characteristics and practices of small livestock producers, focusing on economics and marketing. Data were obtained from a convenience sample of 121 small producers from several South Central Alabama counties, and were analyzed using descriptive statistics, including chi-square tests. The socioeconomic characteristics reflected a higher proportion of part-time farmers; a higher proportion with at most a two-year/technical degree or some college education; and a higher proportion with $40,000 or less annual household income. A majority had been farming more than thirty years, and most had small herds. Also, very few made profits; many sold animals live …

Plenary Presentation On George Washington Carver At The Professional Agricultural Workers Conference, 2014, Kenneth M. Quinn

Professional Agricultural Workers Journal

No abstract provided.

Assessing The Impacts Of Inorganic And Organic Fertilizer On Crop Performance Under A Microirrigation-Plastic Mulch Regime, Niyi S. Omidire, Raymon Shange, Victor Khan, Russell Bean, Jewel Bean

Professional Agricultural Workers Journal

Abstract

This study was conducted at S & B Farm located in Eufaula, AL in 2014. The treatments were Inorganic fertilizer/“Farmer’s Mix” (NPK 13:13:13 + ammonium nitrate mixed in 3:1 ratio); Inorganic fertilizer/“Farmer’s Mix” (NPK 13:13:13 + ammonium nitrate mixed in 3:1 ratio + Bio-grow) plus microbe mix; and Organic Fertilizer – Mighty Grow (4-3-4) with a microbe mix. All fertilizers were applied prior to mulch application after which the following crops squash (Cucurbita pepo L.), cucumber (Cucumis sativus L.), and okra (Abelmoschus esculentus L. Moench) were directly seeded in a complete randomized …

Fatty Acid Transport Protein-2 Inhibitor Grassofermata/Cb5 Protects Cells Against Lipid Accumulation And Toxicity, Nipun Saini, Paul N. Black, David Montefusco, Concetta Dirusso

Department of Biochemistry: Faculty Publications

The inhibition of the fatty acid uptake into non-adipose tissues provides an attractive target for prevention of lipotoxicity leading to obesity-associated non-alcoholic fatty liver disease and type 2 diabetes. Fatty acid transport proteins (FATPs) are bifunctional proteins involved in the uptake and activation of fatty acids by esterification with coenzyme A. Here we characterize Grassofermata/CB5, previously identified as a fatty acid uptake inhibitor directed against HsFATP2. The compound was effective in inhibiting the uptake of fatty acids in the low micro-molar range (IC₅₀ 8–11μM) and prevented palmitate-mediated lipid accumulation and cell death in cell lines that are models for …

Why Do Girls Stay Silent? An Exploratory Research On Young Women's Tolerance Toward Stranger Harassment, Sui Lau

Lingnan Theses

Stranger harassment has been a rising issue regarding gender equality globally. Nevertheless, this issue has been rarely explored in Hong Kong. This study aims at discovering its prevalence, the frequency of its occurrences, local women’s reactions toward it and variables that may determine women’s reactions in a local context. Both personal qualities, including gender-related belief, self-objectification and body image, as well as situational qualities, namely perceived situational norms, are examined.

350 self- administered questionnaires were collected from local women aged between 18 and 25, in either pencil-and-paper or online forms. Results showed that more than 80% of respondents reported experiencing …

The Parthenon, September 25, 2015, Sara Ryan, Bradley Heltzel, Megan Osborne, Shalee Rogney

The Parthenon

The Parthenon, Marshall University’s student newspaper, was published by students Monday through Friday during the regular semester and weekly on Thursdays during the summer. Due to budgetary constraints, beginning with the 2015 Fall semester, the newspaper is only published four days a week. There is no issue on Mondays, physical issues are printed on Tuesdays and Fridays, and online issues only are published on Wednesdays and Thursdays. The editorial staff is responsible for the news and the editorial content.

A Pilot Study Of Demographic And Dopaminergic Genetic Contributions To Weight Change In Kidney Transplant Recipients, Ansley Stanfill, Donna Hathaway, Ann Cashion, Ramin Homayouni, Patricia Cowan, Carol Thompson, Behrouz Madahian, Yvette Conley

Nursing Faculty Publications

Kidney transplant recipients often experience a significant amount of weight gain in the first year post-transplantation. While demographic factors such as age, race, and sex have been associated with weight gain in this population, these factors do not explain all of the variability seen. A number of studies have suggested that genetics also plays a critical role in weight changes. Recently, alterations in the activity of the neurotransmitter dopamine have been associated with weight change, and gene expression studies in kidney transplant recipients have supported this association. The purpose of this pilot study is to first examine the feasibility and …

Fort Hays State University Tiger Weekly, September 25, 2015, University Relations

Tiger Weekly Newsletters

No abstract provided.

Catholic Teaching Brothers: Their Life In The English Speaking World, 1891-1965 (Book Review), John White

Journal of Catholic Education

Review of Catholic Teaching Brothers: Their Life in the English Speaking World, 1891-1965.

Difficult Knowledge And The English Classroom: A Catholic Framework Using Cormac Mccarthy's The Road, Scott Jarvie, Kevin Burke

Journal of Catholic Education

In this article, the authors explore the generative possibilities of risk-taking in the Catholic school English classroom. They associate pedagogical risk with what Deborah Britzman (1998) has called “difficult knowledge”—content that causes students to consider social trauma. Incorporating difficult knowledge meaningfully requires English teachers to take significant pedagogical risks, especially in the Catholic school classroom. Drawing on critical theology and Cormac McCarthy’s novel The Road (2006) as a difficult text, the authors employ a case study looking at how the traumatic difficulty of the novel could be fruitfully taught at a Catholic school. How might students reckon with The Road …

On Feeding The 10 Billion, Patricia Boling

Dawn or Doom Conference

It is commonplace to encounter people close to agriculture in Indiana worrying about how we will produce enough food to feed the projected 10 billion people who will inhabit the earth by 2050. But the assumption that Indiana needs to become even more productive and figure out how to turn out even more of what it does best, corn and soy beans, begs the question, what kind of food are we producing, and how will producing more of it benefit a rapidly increasing world population? We Hoosiers are incredibly productive, but our agricultural output is used primarily to create animal …

Insulating Livestock And Other Farm Buildings, Don D. Jones, William H. Friday, Sherwood S. Deforest

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Environmental Control For Confinement Livestock Housing, Don D. Jones, William H. Friday, Sherwood S. Deforest

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Natural Ventilation For Livestock Housing, Don D. Jones, William H. Friday, Sherwood S. Deforest

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Manure Pit Ventilation In Confinement Livestock Buildings, Don D. Jones, William H. Friday, Sherwood S. Deforest

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Methane Generation From Livestock Waste, Don D. Jones, John C. Nye, Alvin C. Dale

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

It Must Have Been Something I Ate, Wilella Daniels Burgess, April C. Mason

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Overview Of The 2007 Usda Farm Bill Proposals For Reforming The Research Title & Other Proposals To Revamp Public Investments In Agricultural Research, Sonny Ramaswamy

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.

Pasture Leases, J H. Atkinson, David C. Petritz

Historical Documents of the Purdue Cooperative Extension Service Archive

No abstract provided.