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Rationality And Human Value: An Aristotelian Response To Robert Adams, Justin Matchulat

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Dipl 3851/Core 3851 Religion, Law, War, Elizabeth A. Wilson Phd

Diplomacy Syllabi

This course will examine wars of religion and religious views of war, focusing particularly on how religion has informed the international laws of war. We are living through an era fraught with religious warfare - wars animated by religious conflict and wars that use religious abuse as weapons to demoralize and subdue the enemy. The course will focus on three major religious traditions (primarily Judaism, Christianity and Islam) and set in dialogue their respective views of war, assess their contributions to the contemporary laws of war, and examine particular historical episodes of religious conflict - as well as contrary episodes …

Tiger Lily, Maggie Mason Smith

Publications

No abstract provided.

Teresa Of Avila (1515-2015): A Woman Between The Roman Catholic Church’S Crossfire And Exaltation, Karin Heller

Theology Faculty Scholarship

Keynote address "A Teresian Festivity - Celebrate 500 Years of St. Teresa of Avila", a conference at Gonzaga University.

The debates on a woman’s place and function were as passionate in 16th century Spain as they are in today’s Church and civil society. These debates for or against women’s freedom from male domination undergird Teresa’s life and works. From a feminist perspective, her readers have always to bear in mind that she writes under the control of male authorities, even when she is writing to women. What is striking, however, is her twofold struggle. First she struggles for personal freedom …

Oral History: William Iannello, Andrew I. Dalton

Student Publications

Research paper devoted to the life of my grandfather, William Iannello, a second-generation Italian American. His parents came to the United States during the first decade of the 1900s from Calabria, the southernmost region of the Italian mainland.

The Empath’S Travel Log, Pamela J. Thompson

Student Publications

Cynthia Marie Hoffman Studner said of the poem, "This is an ambitious poem that delivers on empathy, just as promised. The poem establishes a metaphor of a “taught thread” that pulls together the traveler and an “orange-coated mutt” spotted in Italy, and this thread weaves throughout the poem as one of continual and deep connection with others. One wonders of the empath’s fate, especially when the poem begins with the story of wives cremated beside their dead husbands. What are the implications of this empathy in terms of its being something the speaker must bear? At times, it is guilt, …

The Niehs Superfund Research Program: 25 Years Of Translational Research For Public Health, Philip J Landrigan, Robert O. Wright, Jose F. Cordero, David L. Eaton, Bernard D. Goldstein, Bernhard Hennig, Raina M. Maier, David M. Ozonoff, Martyn T. Smith, Robert H. Tukey

Animal and Food Sciences Faculty Publications

BACKGROUND: The Superfund Research Program (SRP) is an academically based, multidisciplinary, translational research program that for 25 years has sought scientific solutions to health and environmental problems associated with hazardous waste sites. SRP is coordinated by the National Institute of Environmental Health Sciences (NIEHS). It supports multi-project grants, undergraduate and postdoctoral training programs, individual research grants, and Small Business Innovation Research (SBIR) and Technology Transfer Research (STTR) grants.

RESULTS: SRP has had many successes: discovery of arsenic's toxicity to the developing human central nervous system; documentation of benzene toxicity to hematologic progenitor cells in human bone marrow; development …

Mcnair Scholars Research Journal Volume Viii, St. Mary's University

McNair Scholars Research Journal

This is the eighth journal for the McNair Scholars Program at St. Mary's University.

"Congratulations to the scholar-authors whose work is published in this edition of the McNair Scholars Research Journal. As always, I am impressed with the diverse topics and creative work of our scholars and look forward to their future publications. These projects are, in most cases, the result of a minimum of sixteen weeks of close collaboration with a mentor who is an expert in the scholar's field of study. The opportunity to work in close concert with an accomplished mentor is a key component of the …

2015-October-01-Family Movie Night To Feature "The Minions", University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Animal Therapy, Winston J. Craig

Lake Union Herald

No abstract provided.

Czech Bluegrass In Play, Lee Bidgood

ETSU Faculty Works

Drawing from scholarship on play, ritual, and performance, I propose that Czech bluegrass thrives – as does my fieldwork – in a state of in-betweenness, in a territory that is between work, play, here and there, self and other. Being comfortable with this kind of in-between state is important for fieldwork, and for music-making – play, I find, is both a central activity and metaphor in both. The bluegrass play I discuss in this essay can become a response to the encroachment of Americanization in economic and cultural globalization, but also a way of being “Americanist” – and entirely Czech.

The New Hampshire, Vol. 105 [106], No. 08 (Oct. 1, 2015), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 105, but it is the 106th volume in the series.

Fsd-C10: A More Promising Novel Rock Inhibitor Than Fasudil For Treatment Of Cns Autoimmunity., Yan-Le Xin, Jie-Zhong Yu, Xin-Wang Yang, Chun-Yun Liu, Yan-Hua Li, Ling Feng, Zhi Chai, Wan-Fang Yang, Qing Wang, Wei-Jia Jiang, Guang-Xian Zhang, Bao-Guo Xiao, Cun-Gen Ma

Department of Neurology Faculty Papers

Rho-Rho kinase (Rho-ROCK) triggers an intracellular signalling cascade that regulates cell survival, death, adhesion, migration, neurite outgrowth and retraction and influences the generation and development of several neurological disorders. Although Fasudil, a ROCK inhibitor, effectively suppressed encephalomyelitis (EAE), certain side effects may limit its clinical use. A novel and efficient ROCK inhibitor, FSD-C10, has been explored. In the present study, we present chemical synthesis and structure of FSD-C10, as well as the relationship between compound concentration and ROCK inhibition. We compared the inhibitory efficiency of ROCKI and ROCK II, the cell cytotoxicity, neurite outgrowth and dendritic formation, neurotrophic factors and …

Making Do With Media: Teachers, Technology, And Tactics Of Media Use In American Classrooms, 1919–1946, Katie Day Good

University Faculty Publications and Creative Works

In the last century, teachers have come under pressure to incorporate new media technologies into their lessons. Comparing educational research, press coverage, and teachers' firsthand accounts of mediated instruction between 1919 and 1946, this article highlights a historic discrepancy between anticipated and actual uses of media in classrooms. Drawing on de Certeau's theory of “making do,” the author argues that teachers' efforts to balance high technologies with simpler, more do-it-yourself varieties of media in their lessons constituted critical forms of participation in educational media culture and small acts of resistance against industrial, top-down efforts to streamline, modernize, and technologize their …

Characterization Of Inhibitors Of Fatty Acid Transport Protein-2 In Cell And Animal Models, Nipun Saini

Department of Biochemistry: Dissertations, Theses, and Student Research

Obesity is correlated with insulin resistance and elevated levels of glucose, triglycerides and free fatty acids in blood. This affects overall metabolism and leads to disease. In the obese state, fat also accumulates in non-adipose tissue including liver, muscle and pancreas, where it can lead to cellular dysfunction and death. Currently, only a limited number of drugs are available to combat obesity and it is clear that new drugs, which more narrowly target the metabolic pathways involved, are required. Fatty Acid Transport Proteins (FATPs) are bifunctional proteins involved in the uptake and activation of fatty acids by esterification with coenzyme …

Copyright Policy And The Problem Of Generalizing, Eva E. Subotnik

Faculty Publications

(Excerpt)

Today we have heard a variety of concerns expressed by professional authors, artists and performers. But one of the toughest aspects of determining how to make the copyright system work better is generalizing about what is and is not working. In these brief remarks, I would like to identify three areas that demonstrate this difficulty.

At the outset, a disclaimer: I took the animating theme of this Symposium to be the improvement of the financial stake of individual authors in some kind of direct way. This mode of analysis should be distinguished from other approaches, equally valid, that would …

Columns Fall 2015, Southern Adventist University

Alumni Newsletter

Features the article "Fostering the Curious Mind". Academic risk-takers find a home in the Southern Scholars program, where students embrace an honors curriculum and creative off-campus activities in pursuit of the ultimate interdisciplinary experience.

Demo 23, Columbia College Chicago

Alumni Newsletters

Alumni newsletter from Fall - Winter 2015 entitled "DEMO 23." This issue is 60 pages.

Repeated Trait Evolution Driven By Divergent Natural Selection At Early And Late Stages Of Speciation, Spencer J. Ingley

Theses and Dissertations

Speciation – the process by which new species arise – is of fundamental importance in the biological sciences. The means by which new species arise, and the relationship among living species, has been a topic that has captivated both lay and scientific observers for centuries. In recent years, the study of speciation has enjoyed increased attention, resulting in significant advances in our understanding of how species form. Although our understanding of the processes that contribute to speciation has increased dramatically in recent years, our knowledge of how reproductive barriers accumulate as speciation proceeds is still limited. Thus, studies that evaluate …

Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response To Beta-Adrenergic Stimulation., Guijun Yan, Ni Zhu, Shengdong Huang, Bing Yi, Xiying Shang, Ming Chen, Nadan Wang, Guan-Xin Zhang, Jennifer A Talarico, Douglas G Tilley, Erhe Gao, Jianxin Sun

Center for Translational Medicine Faculty Papers

The orphan nuclear receptor Nur77 plays critical roles in cardiovascular diseases, and its expression is markedly induced in the heart after beta-adrenergic receptor (β-AR) activation. However, the functional significance of Nur77 in β-AR signaling in the heart remains unclear. By using Northern blot, Western blot, and immunofluorescent staining assays, we showed that Nur77 expression was markedly upregulated in cardiomyocytes in response to multiple hypertrophic stimuli, including isoproterenol (ISO), phenylephrine (PE), and endothelin-1 (ET-1). In a time- and dose-dependent manner, ISO increases Nur77 expression in the nuclei of cardiomyocytes. Overexpression of Nur77 markedly inhibited ISO-induced cardiac hypertrophy by inducing nuclear translocation …

Akt Kinase C-Terminal Modifications Control Activation Loop Dephosphorylation And Enhance Insulin Response., Tung O. Chan, Jin Zhang, Brian C. Tiegs, Brian Blumhof, Linda Yan, Nikhil Keny, Morgan Penny, Xue Li, John M. Pascal, Roger S. Armen, Ulrich Rodeck, Raymond B. Penn

Center for Translational Medicine Faculty Papers

The Akt protein kinase, also known as protein kinase B, plays key roles in insulin receptor signalling and regulates cell growth, survival and metabolism. Recently, we described a mechanism to enhance Akt phosphorylation that restricts access of cellular phosphatases to the Akt activation loop (Thr(308) in Akt1 or protein kinase B isoform alpha) in an ATP-dependent manner. In the present paper, we describe a distinct mechanism to control Thr(308) dephosphorylation and thus Akt deactivation that depends on intramolecular interactions of Akt C-terminal sequences with its kinase domain. Modifications of amino acids surrounding the Akt1 C-terminal mTORC2 (mammalian target of rapamycin …

Contents, Anon

Washington Journal of Law, Technology & Arts

No abstract provided.

Janus Kinase 2/Signal Transducer And Activator Of Transcription 3 Inhibitors Attenuate The Effect Of Cardiotrophin-Like Cytokine Factor 1 And Human Focal Segmental Glomerulosclerosis Serum On Glomerular Filtration Barrier., Mukut Sharma, Jianping Zhou, Jean-François Gauchat, Ram Sharma, Ellen T. Mccarthy, Tarak Srivastava, Virginia J. Savin

Manuscripts, Articles, Book Chapters and Other Papers

Recurrence of idiopathic focal segmental glomerulosclerosis (FSGS) after renal transplantation is believed to be caused by a circulating factor(s). We detected cardiotrophin-like cytokine factor 1 (CLCF1), a member of the interleukin 6 family, in the plasma from patients with recurrent FSGS. We hypothesized that CLCF1 contributes to the effect of FSGS serum on the glomerular filtration barrier in vitro. Presently, we studied the effect of CLCF1 on isolated rat glomeruli using an in vitro assay of albumin permeability (P(alb)). CLCF1 (0.05-100 ng/mL) increased P(alb) and caused maximal effect at 5-10 ng/mL (P < 0.001). The increase in Palb was analogous to the effect of FSGS serum. Anti-CLCF1 monoclonal antibody blocked the CLCF1-induced increase in P(alb) and significantly attenuated the effect of FSGS serum (P < 0.001). The heterodimer composed of CLCF1 and cosecreted molecule cytokine receptor-like factor 1 (CRLF1) attenuated the increase in P(alb) caused by CLCF1 or FSGS serum. Western blot analysis showed that CLCF1 upregulated phosphorylation of signal transducer and activator of transcription 3 (STAT3) (Tyr705) in glomeruli. This effect was diminished by the heterodimer CLCF1-CRLF1. Janus kinase 2 (JAK2) inhibitor BMS-1119543 or STAT3 inhibitor Stattic significantly blocked the effect of CLCF1 or FSGS serum on P(alb) (P < 0.001). These novel findings suggest that when monomeric CLCF1 increases P(alb), the heterodimer CLCF1-CRLF1 may protect the glomerular filtration barrier. We speculate that albuminuria in FSGS is related to qualitative or quantitative changes in the CLCF1-CRLF1 complex, and that JAK2 or STAT3 inhibitors may be novel therapeutic agents to treat FSGS.

The Montclarion, October 01, 2015, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Whiteboard Marker Dispenser, Ellen Toennies, Nicole Kawamoto, Aditya Sharma

Mechanical Engineering Design Project Class

In an effort to provide a constant supply of functioning markers to classrooms, labs, and other student spaces around campus, we designed and built a device to incentivize the storage, use, and return of whiteboard markers. Our Whiteboard Marker Dispenser offers customers a visually appealing, interactive manner of ensuring that the collaborative nature of the learning experience will not be hindered by a lack of resources.

The Ethical Implications Of The Military's Product Placement And Brand Integration In Popular Entertainment, Zane P. Ecklund

Research Papers

The military relies heavily on advertising. National defense is itself a product that is marketed to the American taxpayer who not only funds the Pentagon but fights its battles. Recruiting is crucial to maintaining the all-volunteer force created in 1973 when the draft was abolished. While plenty of individuals readily sign up others need more encouragement. As of 2014, 1,412,674 people served on active duty in the U.S. military (http://www.bls.gov/ooh/military/military-careers.htm 2014), and while this number may appear impressive it reflects only a tiny part of the population. This paper will examine in depth how the U.S. military uses product placement …

New Testament Precedents To The Practice Of Contextualization In Contemporary Mission, Boubakar Sanou

Faculty Publications

Although every culture needs to be transformed by the Spirit and the Word of God (Pierson, 2009:257), it is still essential that the communication of the gospel, in whatever setting, seeks to make the gospel concepts and ideas relevant to people within their own cultures (Hiebert, 1985:55). However, the need to be culturally appropriate always should be closely coupled with an in-depth analysis of the Scriptures. Because “people can only understand that which is part of their cultural frame of reference” (Rogers, 2004:65), the presentation of the gospel must be both biblically sound and culturally relevant in order to be …

Mass Spectrometry Based Proteomics And Lipidomics Studies, Huan Kang

Theses and Dissertations

Mass spectrometry has emerged as having a vital role in various applications to biochemical fields. In this thesis, we have utilized a variety of mass spectrometry techniques for both bacteriophage proteomics and colostrum and milk lipidomics studies. Our first study was the proteome characterization of Great Salt Lake bacteriophage NS01 with SDS-PAGE GEL to separate the viral proteins and high performance liquid chromatography (HPLC) coupled with an LTQ Orbitrap to identify the proteins after in-gel digestion. In this project, we have successfully identified 11 proteins with high confidence, p-values < 0.01, including coat protein gp88 with a coverage of 91% and tail protein gp86 with a coverage of 40.96%, which facilitated the classification of NS01 as a T7-like phage. Our second study was the discovery of colostrum and milk biomarkers that can be used to predict the likelihood of development of production-related metabolic diseases (PRMDs) in dairy cows through a lipidomics approach. In this study, an electrospray ionization, time-of-flight mass spectrometer was applied to lipid profiling, quantification and significant biomolecule selection. A Q-Star quadrupole, orthogonal time-of-flight mass spectrometer and an Agilent 6530 accurate-mass quadrupole/time-of flight mass spectrometer were both used for lipid biomarker fragmentation and identification. According to linear discriminative statistical modeling, three panels of biomarkers were defined. A combination of 2 milk lipid predictors, including DG18:0/18:0 and TG 18:0/18:0/18:1, provided PRMD predictions with 75.0% sensitivity at 90.0% specificity. A combination of 3 colostrum lipid predictors, including TG16:0/18:1/18:3, DG16:0/16:0 and C₄₀H₆₀NO, provided PRMD prediction with 90.0% sensitivity at …

Come My Staff, I Lean Upon You: An Iconographic And Contextual Study Of Sticks And Staves From 18th Dynasty Egypt, Nicholas R Brown

Theses and Dissertations

Sticks and staves are some of ancient Egypt’s most versatile tools: they can function as badges of status, walking aids, tools for farmers, weapons for guards, or any combination of these. Though earlier studies have examined the names and types of staves from all periods of ancient Egypt, no former scholarship has exclusively examined the ways in which sticks are used in tomb decoration from the 18th Dynasty. By looking at how the staves are used in elite tomb decoration, one is able to understand how the staff had both a practical use as well as symbolic meaning associated with …

Using Life History Trade-Offs To Understand Core-Transient Structuring Of A Small Mammal Community, Sarah R. Supp, David N. Koons, S.K. Morgan Ernest

Wildland Resources Faculty Publications

An emerging conceptual framework suggests that communities are composed of two main groups of species through time: core species that are temporally persistent, and transient species that are temporally intermittent. Core and transient species have been shown to differ in spatiotemporal turnover, diversity patterns, and importantly, survival strategies targeted at local versus regional habitat use. While the core-transient framework has typically been a site-specific designation for species, we suggest that if core and transient species have local versus regional survival strategies across sites, and consistently differ in population-level spatial structure and gene flow, they may also typically exhibit different life-history …