Digital Commons Network^™

Relationship Among Mif, Mcp-1, Viral Loads, And Hbs Ag Levelsin Chronic Hepatitis B Patients, Hayati̇ Güneş, Rafet Mete, Murat Aydin, Bi̇rol Topçu, Mustafa Oran, Mustafa Doğan, Oğuzhan Yildirim, İlknur Erdem, Aynur Eren Topkaya, Ahmet Gürel

Turkish Journal of Medical Sciences

Background/aim: To determine whether macrophage migration inhibitory factor (MIF) and monocyte chemoattractant protein-1 (MCP-1) levels in patients with hepatitis B (HB) are different than in normal individuals and whether the HB surface antigen (HBs Ag) level and viral load are correlated with each other and with the two aforementioned parameters. Materials and methods: Sera were obtained from 52 chronic active HB (CAHB) patients and 33 healthy controls, and their MIF and MCP-1 levels were measured. Statistical analyses were performed. A value of P < 0.05 was considered statistically significant. Results: The MIF and MCP-1 values of the control group were increased compared to those of the CAHB group. The MIF and MCP-1 levels were negatively correlated with HBs Ag levels and viral loads. The MIF and MCP-1 levels were positively correlated. The HBs Ag levels and the log10 of the viral loads were positively correlated. Conclusion: We conclude that the negative correlation of MIF and MCP-1 with viral load and HBs Ag levels may be due to T-cell deficiency, antinuclear antibody seropositivity, and/or inhibition of chemokine ligand 2 receptors by viral antigens. More studies with a greater number of subjects are needed to evaluate the potential role of MIF and MCP in CAHB.

Visual And Brainstem Auditory Evoked Potentials In Infants Withsevere Vitamin B12 Deficiency, Ni̇hat Demi̇r, Ahmet Koç, Mahmut Abuhandan, Mustafa Çalik, Akin İşcan

Turkish Journal of Medical Sciences

Background/aim: Vitamin B12 plays an important role in the development of mental, motor, cognitive, and social functions via its role in DNA synthesis and nerve myelination. Its deficiency in infants might cause neuromotor retardation as well as megaloblastic anemia. The objective of this study was to investigate the effects of infantile vitamin B12 deficiency on evoked brain potentials and determine whether improvement could be obtained with vitamin B12 replacement at appropriate dosages. Materials and methods: Thirty patients with vitamin B12 deficiency and 30 age-matched healthy controls were included in the study. Hematological parameters, visual evoked potentials, and brainstem auditory evoked …

Histological And Histochemical Studies On The Structure Of Pancreatic Histological And Histochemical Studies On The Structure Of Pancreatic Ducts Of The Goose (Anser Anser), Turgay Deprem, Serap Koral Taşçi, Seyi̇t Ali̇ Bi̇ngöl, Ebru Karadağ Sari, Şahi̇n Aslan, Serap İlhan

Turkish Journal of Veterinary & Animal Sciences

The aim of the present study was to determine the histological structure and histochemical properties of the pancreatic ducts in the goose Anser anser. Pancreatic ducts of 6 male and 6 female geese were examined. Crossman’s triple stain and Masson’s trichrome stain were used for histological examination, and periodic acid–Schiff, alcian blue, periodic acid–Schiff/alcian blue, and aldehyde fuchsin/alcian blue stainings were performed for histochemical examination. Dorsal and ventral pancreatic ducts were found that transfer pancreatic secretion into the duodenum of the goose, and these channels were found to have a histologically similar structure. No differences were detected between male and …

Cell-Based Therapy And Rehabilitation With Prosthetic Limbs In A Dog, Jayakrushna Das, Indramani Nath, Padmanav Routray, Rabindra Kumar Das, Sidhartha Sankar Behera

Turkish Journal of Veterinary & Animal Sciences

A 5-year-old male dog was presented with the complaint of a chronic nonhealing wound on both hind legs. The wound occurred during a serious train accident that caused loss of both hind limbs below the hock joint. Since then, the wound did not respond to any standard treatment for up to 4 months. Again it was dressed for 15 days, but it did not show any improvement. With the consent of the owner, cell-based therapy was conducted by collecting bone marrow from the proximal anteromedial aspect of the tibia. After the application of bone marrow derived mesenchymal stem cells (BM-MSCs) …

Molecular Characterization Of The Hspa1a Gene By Single-Strandconformation Polymorphism And Sequence Analysis In Holstein-Friesiancrossbred And Deoni Cattle Raised In India, Ramesha P. Kerekoppa, Akhila Rao, Marappa Basavaraju, Gujjar Ramachandra Geetha, Lakhsminarayan Krishnamurthy, Thota Vl Narasimha Rao, Dayal Nitai Das, Kataktalware Mukund

Turkish Journal of Veterinary & Animal Sciences

A group of proteins called heat shock proteins (HSPs) are synthesized during heat stress. They are expressed at high levels when exposed to stress. Polymorphism in HSPs has been reported to be associated with heat tolerance and reproductive performance in cattle. The present study aimed to investigate the polymorphisms in the coding region of the HSPA1A gene in Holstein-Friesian (HF) crossbreds and the Deoni breed of cattle. Genomic DNA was extracted from 94 animal blood samples and was subjected to polymerase chain reaction-single strand conformation polymorphism analysis, which revealed 14 band patterns in Deoni cattle and 8 band patterns in …

Prevalence Of Toxoplasma Gondii In Sheep Meats Purchased From Retailstores In Central Anatolia, Turkey, Kader Yildiz, Fatma Çi̇ğdem Pi̇şki̇n, Armağan Erdem Ütük, Sami̇ Gökpinar

Turkish Journal of Veterinary & Animal Sciences

Toxoplasmosis is one of the most important foodborne parasitic diseases of humans. In particular, sheep muscles are significant sources of infection in the transmission of toxoplasmosis. Carnivorism is the most important transmission route for human populations. The aim of this study was to detect the prevalence of Toxoplasma gondii tissue cysts in sheep meats in retail stories of Turkey. A total of 250 boneless sheep meat samples were purchased from randomly selected retail stores in different locations of Ankara and Kırıkkale provinces of Turkey. The homogenized meat samples were centrifuged with Percoll dilutions. The tissue cysts were removed by pipette …

Association Of Mx1 Gene Polymorphism With Some Economic Traits In Meishan Pigs, Xue Mei Yin, Ying Liu, Wen Hua Dong, Qiao Hui Zhao, Guo Qiang Zhu, Sheng Long Wu, Wen Bin Bao

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to determine the association of polymorphisms in exon 14 of the Mx1 gene with significant economic traits in Meishan pigs, with the aim of identifying genetic markers of disease resistance. PCR-RFLP analysis of exon 14 of the Mx1 gene was conducted and associations with some cytokine levels (IFN-$\alpha$, IFN-$\gamma$, IL-2, IL-6, IL-10, and IL-12), early body weight (birth weight, 20-day weight, and 40-day weight), and reproductive performance within different parities (total number born, number born alive, number in live weaning litter, birth weight, and weaning weight) were analyzed. The results showed that there were AA, AB, …

Clinical And Radiographic Characterization Of Xenotransplantation Of Rat Bonemarrow-Derived Mesenchymal Stem Cells For Repair Of Radial Defects Of Rabbit, Betania Monteiro, Lukiya Favarato, Pablo Carvalho, Barbara Okano, Maria Antonia Menegatti, Alvaro Oliveira, Bianka Santos, Ricardo Del Carlo

Turkish Journal of Veterinary & Animal Sciences

This study aimed to evaluate the clinical and radiographic aspects of xenogenic transplantation of rat bone marrow-derived mesenchymal stem cells (MSCs) for the repair of radial bone defects of rabbit. Bone marrow derived MSCs collected from Wistar rats were expanded, differentiated, and labeled in the laboratory. In the fourth passage, the cultures were pelleted in aliquots of 107 cells/50 μL and transplanted in situ into the lesions. Thirty-six rabbits were used in the in vivo study. In all animals, defects were created by removing a bone segment of 1.0 cm in length in the right radius. The rabbits were divided …

A Novel Approach For Determination Of Chicken Sexing At An Early Stage Of Development By Using Loop-Mediated Isothermal Amplification Method, Sung Woo Kim, Jin Seok Choi, Neelesh Sharma, Yeoung Gyu Ko, Yoon Jung Do, Mijeong Byun, Hwan Hoo Seong, Soo Bong Park, Dong Kee Jeong

Turkish Journal of Veterinary & Animal Sciences

The monomorphism of newly hatched chicks is a major hurdle for poultry farmers at the time of sexing. The traditional sexing techniques are inaccurate and time-consuming. Therefore, the present study aimed to develop a loop-mediated isothermal amplification (LAMP)-based sex determination method to obtain a higher separation accuracy rate as compared to conventional methods. LAMP is a simple, quick, and relatively inexpensive diagnostic tool. Genomic DNA was extracted from the blood samples of Leghorn and Korean native chicks for LAMP. Two sets of primer were designed, consisting of four isothermal amplification primers in each, to amplify the female sex-specific sequence (HUR0417) …

Prevalence Of Blaz Gene And Other Virulence Genes In Penicillin-Resistant Staphylococcus Aureus Isolated From Bovine Mastitis Cases In Gansu, China, Feng Yang, Qi Wang, Xurong Wang, Ling Wang, Min Xiao, Xinpu Li, Jinyin Luo, Shidong Zhang, Hongsheng Li

Turkish Journal of Veterinary & Animal Sciences

Staphylococcus aureus is a major etiological agent of bovine mastitis worldwide. In this study, 37 strains of S. Aureus resistant to penicillin were isolated from bovine mastitis cases in Gansu Province for investigating blaZ and virulence-related genes, including tst, eta, etb, lukPV, lukED, lukM, hla, hlb, hld, and edin. Antibiotic resistance was based on disk diffusion method and blaZ and virulence-associated genes were studied by polymerase chain reaction. Penicillin resistance gene blaZ was detected in 35/37 (94.6%) of penicillin-resistant S. Aureus isolates. tst, lukPV, lukED, hla, hlb, and hld were observed in 5.4%, 2.7%, 89.2%, 70.3%, 73.0%, and 70.3% of …

Significance Of Homocysteine And Cardiac Markers In Cattle With Hypocalcemia, Yildiray Başbuğan, Nazmi̇ Yüksek, Nuri̇ Altuğ

Turkish Journal of Veterinary & Animal Sciences

This study aimed to determine the levels of homocysteine and cardiac markers in cows with hypocalcemia. This research was conducted with a total of 20 cows, including 10 with hypocalcemia and 10 healthy controls. Hypocalcemia was diagnosed by determining low blood calcium (Ca) levels, and a standard hypocalcemia treatment was initiated in those cows with the disease. Blood samples were taken before the treatment and again 12 h after the treatment, and there was no significant difference in the homocysteine levels between the groups. Ca, ionized calcium (Ica), magnesium (Mg), and phosphorus (P) levels were lower, while cardiac troponin I …

Cover And Contents

Turkish Journal of Veterinary & Animal Sciences

No abstract provided.

2015-2016 Graduate Catalog, Morehead State University

Morehead State Catalog Archive

2015-2016 graduate catalog for Morehead State University.

2015-2016 Undergraduate Catalog, Morehead State University

Morehead State Catalog Archive

2015-2016 undergraduate catalog for Morehead State University.

A Quantum Theory Of Consciousness May Require A Paradigm Shift In Biology, Maurice Goodman

Articles

It is often assumed that the known physical laws form a closed system and are complete. It is also assumed that biological theories require no additional principles that are fundamental other than those we already know. Assumptions such as these are acting as a barrier to progress in biological theories and an understanding of consciousness. This paper examines the unexplained inconsistencies among fundamental particles and forces and the fundamental gaps in our knowledge of biology and the cell in particular that may impact on such progress. Also, the laws of quantum mechanics are examined and found to be grossly incomplete. …

Primer Efficacy In The Dna Barcoding Of Spiders, Rhennetta Jo Bork

Honors Program Theses

DNA barcoding is the process of amplifying a 650 base pair segment of the sequence of the mitochondrial gene cytochrome c oxidase (COI), and amplifying this gene with a polymerase chain reaction (PCR). It is used to help identify and distinguish animal species and also to help determine genetic differences in species. DNA barcoding can be especially useful when working with spiders since they tend to be very small and hard to distinguish. However, achieving a DNA barcode can be difficult and thus techniques to improve the method of DNA barcoding can be helpful. This research looked into the different …

Stare Decisis In The Second-Best World, Randy J. Kozel

Journal Articles

If judges disagree about the proper interpretation of the law, can they find common ground in the treatment of precedent? The doctrine of stare decisis weighs the value of legal continuity against the value of legal accuracy. But that analysis is complicated by pervasive disputes over the implications of legal error. Likewise, the scope of a precedent's impact in future cases depends on underlying assumptions about the ends and means of legal interpretation. When those assumptions vary among judges, so too will applications of stare decisis. For stare decisis to promote the continuity and impersonality of law, it requires an …

The Fair Market Value Of Public Resources, Bruce R. Huber

Journal Articles

This Article explores the problem of public resource sales with particular reference to natural resources managed by the federal government. Lands owned by the United States hold trillions of dollars' worth of natural resources. Federal agencies earn billions in annual revenue from resource sales, yet critics assert that billions more could be reaped if resources were sold for a fair price. Although federal law has increasingly required that agencies price resources at fair market value, this requirement is surprisingly difficult to interpret and even more dfficult to implement and enforce. This Article analyzes the various forces that bear on public …

The Hughes Court Docket Books: The Late Terms, 1937–1940, Barry Cushman

Journal Articles

For many years, the docket books kept by a number of the justices of the Hughes Court have been held by the Office of the Curator of the Supreme Court. Yet the existence of these docket books was not widely known, and access to them was highly restricted. Recently, however, the Court adopted new guidelines designed to increase access to the docket books for researchers. This article offers the first-ever examination of the available docket book entries relevant to what scholars commonly regard as the major decisions of rendered during the late years of the Hughes Court, from the 1937 …

A Survey Of Smartwatch Platforms From A Developer’S Perspective, Ehsan Valizadeh

Technical Library

Technological innovation has made it possible to package a powerful processor and memory subsystem coupled with a high-resolution display, wireless communication, and specific sensors into a device known as the smartwatch. This device introduces a new set of new challenges such as battery life, user interaction, and other how to create applications for it. Smartwatches are connected to the Internet and provide gesture interaction and the ability to continuously monitor a user’s physical activity. The smartwatch has access to the smartphone and therefore can be used as a second display to show users various notifications from the phone such as …

Creating 3d Foldable Papercraft From Dynamically Generated Scalable Vector, Daniel Slaughter

Technical Library

This project demonstrates the advantages of using Scalable Vector Graphics (SVG) over traditional image types (JPEG, GIF, PNG, etc.) for 3D modeling on the Web. The project uses an SVG to dynamically update the colors and layers, and apply it as a texture on a 3D model. Since the 3D model is based on a 2D texture, the project also demonstrates how to print and fold it back into a 3D papercraft.

De Novo Assembly Of The Chimpanzee Transcriptome From Nextgen Mrna Sequences, Mnirnal D. Maudhoo, Jacob D. Madison, Robert B. Norgren

Journal Articles: Genetics, Cell Biology & Anatomy

BACKGROUND: Common chimpanzees (Pan troglodytes) and bonobos (Pan paniscus) are the species most closely related to humans. For this reason, it is especially important to have complete and accurate chimpanzee nucleotide and protein sequences to understand how humans evolved their unique capabilities. We provide transcriptome data from four untransformed cell types derived from the reference Pan troglodytes, "Clint", to better annotate the chimpanzee genome and provide empirical validation for proposed gene models of this important species.

FINDINGS: RNA was extracted from primary cells cultured from four tissues: skin, adipose stroma, vascular smooth muscle and skeletal muscle. These four RNA samples …

Lead Exposure Of Obligate Avian Scavengers In Eastern North America, Shannon Behmke

Graduate Theses, Dissertations, and Problem Reports (ETD)

Lead is a toxic element within the body of living organisms. Lead poisoning cases still occur in both humans and wildlife on a regular basis in the United States. Although the harmful effects of lead within the body are well known, such as decreased IQ in children, increased renal dysfunction, hypertension, anemia, and other morbid and mortal consequences in humans and wildlife, lead continues to be used in anthropogenic activities today. Through the use of lead in ammunition and fishing sinkers, and its presence in coal-fired power plant and other industrial emissions, lead is dispersed throughout modern human and natural …

2015 Annual Research Report: Greater Sage-Grouse Habitat Use Patterns And Vital Rates In The Morgan-Summit Sage-Grouse Management Area: Conservation Implications For Managers, B. Flack, Terry A. Messmer

Wildland Resources Faculty Publications

No abstract provided.

Vincentian Heritage 32:2

Vincentian Studies

No abstract provided.

Interpretation, Jamal Greene

Faculty Scholarship

Interpretation is the means by which the Constitution and its clauses are brought to bear on actual cases and controversies. Although much of the Constitution appears self-explanatory, as with its requirement that the president be at least thirty-five years old, much is subject to reasonable disagreement. The approaches to interpretation that form this chapter’s subject are the main tools scholars and judges have developed to resolve that disagreement. Those tools encompass five domains of argumentation, broadly conceived: text, history, structure, precedent, and consequences. As a general matter, interpretation that draws on resources wholly outside these five domains — via an …

Ownership And Possession, Thomas W. Merrill

Faculty Scholarship

One of the enduring mysteries about property is why the law protects both ownership and possession. In a pre-modern world, with low rates of literacy and no formal method of registering titles, one can understand why the law would protect possession. In such a world, there may be no concept of property beyond the understanding that persons should respect possessory rights established by others. It is less clear why possession should be protected once property comes to be understood as ownership. Ownership and possession will commonly overlap, and protecting ownership will protect possession. Nevertheless, even in the most sophisticated legal …

Delegation, Accommodation, And The Permeability Of Constitutional And Ordinary Law, Gillian E. Metzger

Faculty Scholarship

To some, the very idea of the constitutional law of the administrative state is an oxymoron. On this view, core features of the national administrative state — broad delegations and the combination of legislative, executive, and judicial power within administrative agencies, particularly agencies that are headed by unelected executive officials only removable on narrow grounds — are fundamentally at odds with both constitutional separation of powers principles and due process. To others, no such conflict between contemporary administrative governance and the Constitution exists, and assertions of the administrative state’s unconstitutionality rest on basic misunderstandings of what separation of powers and …

Beginnings: The Viejo Period, Jane H. Kelley, Michael T. Searcy

Faculty Publications

he history of the Medio Period is marked by population growth, aggregation, ideological shifts, and the building of the large, central polity of Paquimé (Casas Grandes). But before this colossal social transformation took place, people in northwest Chihuahua lived a lifestyle that had persisted for at least 400 years, which is known as the Viejo Period. his period is far from the beginning of human occupation in this area; Paleo points, extensive Archaic remains, the early agricultural site of Cerro Juanaqueña (Hard and Roney 1998), and an early pithouse period preceded Paquimé and can be seen as more distant precursors …

You Think You Know The Story: Novelty, Repetition, And Lovecraft In Whedon And Goddard’S The Cabin In The Woods, Gerry Canavan

English Faculty Research and Publications

No abstract provided.