Digital Commons Network^™

Is The Use Of Itraconazole Effective In The Treatment Of Patients Diagnosed With Tinea Versicolor And If So, What Is The Optimal Dosage?, Ashley B. Pachutski

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not itraconazole is effective in the treatment of patients diagnosed with tinea versicolor and if so, what is the optimal dosage.

STUDY DESIGN: Review of three peer-reviewed, randomized control trials (RCTs), two of which were published in 2002 and one in 2010.

DATA SOURCES: Studies were researched through PubMed and selected based on the type of study (RCT), their relevance to the clinical question, and if they were POEMS (patient oriented evidence that matters).

OUTCOME(S) MEASURED: Patient’s subjective measurement of the severity of pruritis, erythema, scaling, and …

Inspectional Services Bureau (Isb) Internal Investigations Unit Annual Report 2014, Tennessee. Department Of Safety & Homeland Security.

Miscellaneous Reports

No abstract provided.

In Defense Of Marianne Dashwood: A Categorization Of Language Into Principles Of Sense And Sensibility, Ashley Bonin

The Oswald Review: An International Journal of Undergraduate Research and Criticism in the Discipline of English

No abstract provided.

Feminism And The Force Of Institutions In Twenty-First Century Dystopian Novels, Stephanie Roman

The Oswald Review: An International Journal of Undergraduate Research and Criticism in the Discipline of English

No abstract provided.

The Oswald Review Undergraduate Research And Criticism In The Discipline Of English: Volume 17 Fall 2015

The Oswald Review: An International Journal of Undergraduate Research and Criticism in the Discipline of English

No abstract provided.

Multimedia Learning For Increasing Knowledge On Energy Efficiency And Promotion Of Proenvironmental Behavior: A Study Of Undergraduate Students In Costa Rica, Yoselyn Walsh

Open Access Theses

Promotion of energy efficiency practices among household has been employed in many interventions with a varying degree of success, mainly on developed countries. The purpose of the study is to promote and measure knowledge of proenvironmental behavior in undergraduate students in the Costa Rica Institute of Technology. The intervention used for this purpose provided personal and altruistic information about the impact of energy consumption activities in household. People’s perceptions and attitudes about behaviors that contribute and mitigate climate change were also investigated. Participants were students from undergraduate programs who are also inhabitants of the residence hall provided by the institution. …

Effects Of Supplemental Energy On Beef Female Performance, Sara Ann Mccullough

Open Access Theses

ABSTRACT

Hip Hop Culture In A Small Moroccan City, Brian Seilstad

Journal of Hip Hop Studies

This paper explores Hip Hop culture by tracing its development from the global level through the Arab world to finally its manifestation in Morocco. Hip Hop culture is defined broadly as a wide range of artistic expressions-rap, graffiti, breakdancing, DJing, etc.-and also a mind-set or way of life. The focus on the Moroccan context starts at the national level, pointing out some of the key artists, issues Moroccan Hip Hop faces, and how this has been explored by scholars of Hip Hop. The paper focuses on an ethnographic exploration of Hip Hop culture in Ifrane, a small Moroccan city. An …

Hip Hop Culture In A Small Moroccan City, Brian Seilstad

Journal of Hip Hop Studies

This paper explores Hip Hop culture by tracing its development from the global level through the Arab world to finally its manifestation in Morocco. Hip Hop culture is defined broadly as a wide range of artistic expressions-rap, graffiti, breakdancing, DJing, etc.-and also a mind-set or way of life. The focus on the Moroccan context starts at the national level, pointing out some of the key artists, issues Moroccan Hip Hop faces, and how this has been explored by scholars of Hip Hop. The paper focuses on an ethnographic exploration of Hip Hop culture in Ifrane, a small Moroccan city. An …

Silencing Mist1 Gene Expression Is Essential For Recovery From Acute Pancreatitis, Anju Karki, Sean E. Humphrey, Rebecca E. Steele, David A. Hess, Elizabeth J. Taparowsky, Stephen F. Konieczny

Department of Biological Sciences Faculty Publications

Acinar cells of the exocrine pancreas are tasked with synthesizing, packaging and secreting vast quantities of pro-digestive enzymes to maintain proper metabolic homeostasis for the organism. Because the synthesis of high levels of hydrolases is potentially dangerous, the pancreas is prone to acute pancreatitis (AP), a disease that targets acinar cells, leading to acinar-ductal metaplasia (ADM), inflammation and fibrosis-events that can transition into the earliest stages of pancreatic ductal adenocarcinoma. Despite a wealth of information concerning the broad phenotype associated with pancreatitis, little is understood regarding specific transcriptional regulatory networks that are susceptible to AP and the role these networks …

Limitations Of Host Plant Use In Two Andean Altinote (Nymphalidae, Heliconiinea, Acraeini), Butterflies, From A Tritrophic Perspective, Karen M. Pedersen

Browse all Theses and Dissertations

Despite the clear advantages of generalist feeding, many insect herbivores feed on a relatively small number of available host plants with in phylogenetically restricted groups. To better understand patterns of host plant use I used the sister species Altinote stratonice and Altinote dicaeus and their overlapping but distinct host plant range. I measured physiological effects of plants by using development time, pupal mass, and survival. To determine the importance of enemies I quantified rates of parasitism and rates of predation. Finally I measured host plant frequency, and host plant abundance. I found that survival of A. dicaeus and A. stratonice …

Sensorimotor Analysis Of Oxaliplatin Treated Rats, Krystyna Blanka Wieczerzak

Browse all Theses and Dissertations

There is currently no direct evidence that chemotherapy induced peripheral neuropathy (CIPN) necessarily explains the sensorimotor deficits seen in 90% patients treated with oxaliplatin (OX). Some patients develop sensory symptoms without CIPN. Our laboratory reported abnormal signaling from IA afferents in OX treated rats with no evidence of neuropathy. We hypothesized that in the absence of CIPN, the behavioral disability is associated with impaired sensory encoding in OX treated rats. The purpose of this study was to investigate the sensorimotor abilities of OX treated rats. The battery of behavioral tests was designed to address proprioception and sensorimotor integration. In the …

Automatic Turning Movements Identification System: Intersection Error Analysis, Brandon Ross Orr, Joseph Thomas Lanni

Williams Honors College, Honors Research Projects

To lessen congestion at intersections, traffic identification systems are placed at roadway intersections in order to collect vehicle data. These traffic identification systems include various types of detectors that can identify the presence of vehicles in real-time. However, these detectors can only detect their presence and not their turning movements. To fix this issue, The University of Akron has developed a program that can automatically identify vehicle turning movements and is called the Automatic Turning Movement Identification System, or ATMIS. ATMIS uses mathematical algorithms to compute the vehicle’s turning movements based on a sink and feed detector paring. During traffic …

Stable Isotopes In Seabirds, Kimberly Gosciak

Williams Honors College, Honors Research Projects

Seabirds are a highly endangered group of vertebrates; they are more threatened than any other group of bird. However, the Common Murre is one species that is showing an increasing population trend; I found that Common Murres have shown a significant increase in δ¹⁵N since 1994, in contrast to the threatened Marbled Murrelet, which has a similar biology but has shown decreasing δ¹⁵ N values that typically correlate with declining population size. This is potentially due to sexual dimorphism that allows for the Common Murre to fill a larger niche. While I found no statistical difference between …

Therapeutic Animal Camp For Children Affected By Cancer, Katie Fleck

Williams Honors College, Honors Research Projects

This research project looks at the therapeutic benefits of an animal camp for children touched by cancer. Animal assisted therapy techniques were used for children to connect with animals during a week long summer camp. The benefits of working with animals are discussed, as well as research on many therapeutic activities including reiki, labyrinth walking, zentangle drawing, yoga, and drumming. Past camp attendees were recorded and interviewed about their personal experiences at camp. Caregivers of campers were also interviewed, who shared about the positive impact camp had on their family. Multiple benefits were found for this type of camp in …

Predicting Key Residues Relevant To Hiapp Fibril Stability Using Permuted Residue Minimal Distance Pairs Of Riapp And Hiapp Dimers, Zak Kohler

Williams Honors College, Honors Research Projects

In order to discover the most significant residues involved in hIAPP fibril formation, Replica Exchange Molecular Dynamics (REMD) trajectories of both fibril forming hIAPP dimers and non-fibril-forming rIAPP dimers were analyzed. An import heuristic for this is the minimum distance between the peptides. To gain a greater resolution than the standard center of mass distance or 1-1, 2-2, etc.\ residue distances, every permutation of residue distance between molecules of the dimer was measured ranked. It was found that while the rIAPP had a single favored contact, (26 10), hIAPP appeared to have a network of at least three significant contacts: …

Potential Role Of Protein Kinase Cbeta In High Fat Diet-Induced Adipose Dysfunction By Regulating Autophagy Levels, Neil Mehta

Williams Honors College, Honors Research Projects

Obesity is the most common nutritional disorder in the United States and worldwide. Public health efforts and other anti-obesity measures clearly have not controlled the obesity epidemic. There is a great need to understand the pathogenic mechanisms underlying fat accumulation. Research of the past decade supports a prominent role for diet-induced adipose tissue dysfunction in the development and/or progression of obesity and associated insulin resistance. Potential mechanisms for the development of adipose tissue dysfunction include ectopic (visceral) fat accumulation, genetic factors, and alterations in autophagy and inflammatory processes. However, the molecular mechanisms linking dietary fat intake with alterations in adipose …

Regleprudence – At Oira And Beyond, Nestor M. Davidson, Ethan J. Leib

Faculty Scholarship

There are significant domains of legality within the administrative state that are mostly immune from judicial review and have mostly escaped the attention of legal theorists. While administrative law generally focuses on the products of agency action as they are reviewed by the judiciary, there are important aspects of regulatory activity that are legal or law-like but rarely interrogated by systematic analysis with reference to accounts about the role and nature of law. In this Article, we introduce a category of analysis we call "regleprudence," a sibling of jurisprudence and legisprudence. Once we explore some regleprudential norms, we delve into …

Privacy, Police Power, And The Growth Of Public Power In The Early Twentieth Century: A Not So Unlikely Coexistence, Carol Nackenoff

Political Science Faculty Works

No abstract provided.

Ancient Humans Influenced The Current Spatial Genetic Structure Of Common Walnut Populations In Asia., Paola Pollegioni, Keith E. Woeste, Francesca Chiocchini, Stefano Del Lungo, Irene Olimpieri, Virginia Tortolano, Jo Clark, Gabriel E. Hemery, Sergio Mapelli, Maria Emilia Malvolti

Department of Forestry & Natural Resources Faculty Publications

Common walnut (Juglans regia L) is an economically important species cultivated worldwide for its wood and nuts. It is generally accepted that J. regia survived and grew spontaneously in almost completely isolated stands in its Asian native range after the Last Glacial Maximum. Despite its natural geographic isolation, J. regia evolved over many centuries under the influence of human management and exploitation. We evaluated the hypothesis that the current distribution of natural genetic resources of common walnut in Asia is, at least in part, the product of ancient anthropogenic dispersal, human cultural interactions, and afforestation. Genetic analysis …

The Antitumorigenic Function Of Egfr In Metastatic Breast Cancer Is Regulated By Expression Of Mig6, Michael Wendt, Whitney K. Williams, Pete E. Pascuzzi, Nikolas G. Balanis, Barbara J. Schiemann, Cathleen R. Carlin, William P. Schiemann

Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

Numerous studies by our lab and others demonstrate that epidermal growth factor receptor (EGFR) plays critical roles in primary breast cancer (BC) initiation, growth and dissemination. However, clinical trials targeting EGFR function in BC have lead to disappointing results. In the current study we sought to identify the mechanisms responsible for this disparity by investigating the function of EGFR across the continuum of the metastatic cascade. We previously established that overexpression of EGFR is sufficient for formation of in situ primary tumors by otherwise nontransformed murine mammary gland cells. Induction of epithelial-mesenchymal transition (EMT) is sufficient to drive the metastasis …

Managing Free Play In Early Childhood: Teachers Don’T Need To End The Trend, Elizabeth D'Apolito

Williams Honors College, Honors Research Projects

No abstract provided.

What Causes Variation In Peacock Feather Colors?, Chance Mitan

Williams Honors College, Honors Research Projects

Sexual selection favoring the most attractive peafowl is very well understood, but the answer to what drives the variation in peacock feather coloration remains a mystery. The goal of this experiment is to determine the precise physical mechanism used by peafowl to generate such elaborate color variations in the eyespots of their tail feathers among males within the species. Barbs from eyespots of Pavo cristatus were embedded in an epoxy resin, sectioned on a microtome, and TEM images of the nanostructure within each barbule were analyzed. Results indicate that melanosome diameter is a significant positive predictor of iridescence and that …

Characterization Of Noncovalent Complexes Of Polyelectrolytes By Mass Spectrometry, Anthony J. Marino

Williams Honors College, Honors Research Projects

Various ions of poly-L-lysine and polystyrene sulfonic acid were successfully observed first within a matrix-assisted laser desorption/ionization mass spectrometer and subsequently in an electrospray ionization mass spectrometer. The successful ionization of these polymers allowed for studies to be performed on the noncovalent interactions between the two. Noncovalent interactions were effectively studied on both instruments, but further quantified using tandem mass spectrometry found within the MALDI system and ion-mobility mass spectrometry found within the electrospray ionization system. As a result of employing the use of ion-mobility, various different stoichiometries and charges of polyelectrolyte complexes could be distinguished.

Segregating The Effects Of Seed Traits And Common Ancestry Of Hardwood Trees On Eastern Gray Squirrel Foraging Decisions, Mekala Sundaram, Janna R. Willoughby, Nathanael Issac Lichti, Michael A. Steele, Robert K. Swihart

Department of Forestry & Natural Resources Faculty Publications

The evolution of specific seed traits in scatter-hoarded tree species often has been attributed to granivore foraging behavior. However, the degree to which foraging investments and seed traits correlate with phylogenetic relationships among trees remains unexplored. We presented seeds of 23 different hardwood tree species (families Betulaceae, Fagaceae, Juglandaceae) to eastern gray squirrels (Sciurus carolinensis), and measured the time and distance travelled by squirrels that consumed or cached each seed. We estimated 11 physical and chemical seed traits for each species, and the phylogenetic relationships between the 23 hardwood trees. Variance partitioning revealed that considerable variation in foraging investment was …

Assessing The Permeability Of Landscape Features To Animal Movement: Using Genetic Structure To Infer Functional Connectivity, Sarah J. Anderson, Elizabeth M. Kierepka, Robert K. Swihart, Emily K. Latch

Department of Forestry & Natural Resources Faculty Publications

Human-altered environments often challenge native species with a complex spatial distribution of resources. Hostile landscape features can inhibit animal movement (i.e., genetic exchange), while other landscape attributes facilitate gene flow. The genetic attributes of organisms inhabiting such complex environments can reveal the legacy of their movements through the landscape. Thus, by evaluating landscape attributes within the context of genetic connectivity of organisms within the landscape, we can elucidate how a species has coped with the enhanced complexity of human altered environments. In this research, we utilized genetic data from eastern chipmunks (Tamias striatus ) in conjunction with spatially explicit habitat …

Ancient Humans Influenced The Current Spatial Genetic Structure Of Common Walnut Populations In Asia, Paola Pollegioni, Keith E. Woeste, Francesca Chiocchini, Stefano Del Lungo, Irene Olimpieri, Virginia Tortolano, Jo R. Clark, Gabriel E. Hemery, Sergio P. Mapelli, Maria Emilia Malvolti

Department of Forestry & Natural Resources Faculty Publications

Common walnut (Juglans regia L) is an economically important species cultivated worldwide for its wood and nuts. It is generally accepted that J. regia survived and grew spontaneously in almost completely isolated stands in its Asian native range after the Last Glacial Maximum. Despite its natural geographic isolation, J. regia evolved over many centuries under the influence of human management and exploitation. We evaluated the hypothesis that the current distribution of natural genetic resources of common walnut in Asia is, at least in part, the product of ancient anthropogenic dispersal, human cultural interactions, and afforestation. Genetic analysis combined with ethno-linguistic …

Selective Sweep Analysis In The Genomes Of The 91-R And 91-C Drosophila Melanogaster Strains Reveals Few Of The ‘Usual Suspects’ In Dichlorodiphenyltrichloroethane (Ddt) Resistance, Laura D. Steele, Brad Coates, M Carmen Valero, Weilin Sun, Keon Mook Seong, William M. Muir, John M. Clark, Barry R. Pittendrigh

Department of Animal Sciences Faculty Publications

Adaptation of insect phenotypes for survival after exposure to xenobiotics can result from selection at multiple loci with additive genetic effects. To the authors’ knowledge, no selective sweep analysis has been performed to identify such loci in highly dichlorodiphenyltrichloroethane (DDT) resistant insects. Here we compared a highly DDT resistant phenotype in the Drosophila melanogaster (Drosophila) 91-R strain to the DDT susceptible 91-C strain, both of common origin. Whole genome re-sequencing data from pools of individuals was generated separately for 91-R and 91-C, and mapped to the reference Drosophila genome assembly (v. 5.72). Thirteen major and three minor effect chromosome intervals …

Relating Personality And Body Size To Social Networks And Dispersal Behavior In Female Western Mosquitofish (Gambusia Affinis), Janean Kazimir

Williams Honors College, Honors Research Projects

No abstract provided.

Creating A Mobile Game, Timothy Jasany

Williams Honors College, Honors Research Projects

The world we live in today is one that revolves around technology. Whether you are checking your email or paying a bill, most of these actions can be accomplished through the use of technology. One of the most powerful pieces of technology is a cell phone, which can accomplish most tasks any other device can do. Since this piece of technology is growing better and better each day I decided to learn how to program android devices. Cell phones are becoming more widely used by the general public, which I think means that in the near future that cell phones …