Digital Commons Network^™

The Effectiveness Of A Computer-Assisted, Cognitive-Behavior Program For Treating Anxiety Symptoms In Children With Autism Spectrum Disorder, Jennifer A. Zabel

PCOM Psychology Dissertations

Autism Spectrum Disorder (ASD) is a complex and multifaceted, neurodevelopmental disorder that severely impacts children and families across a variety of settings. Prevalence rates of ASD are continuing to increase rapidly, with sizeable intervention and treatment costs placed on families and society. Further complicating the matter, many individuals with ASD also evidence co-occurring anxiety symptoms or disorders and tend to be at a higher risk for developing such problems when compared to other clinical populations or typically developing children. This study investigated the effectiveness of a computer-assisted CBT program, Camp Cope-A-Lot (CCAL), in regards to reducing anxiety symptoms in four …

Impact Of Group Cognitive Behavior Therapy On Adolescents With Deficits In Inhibition, Jessica L. Morley

PCOM Psychology Dissertations

Existing literature connects impulse control dysfunction to high-risk behaviors and negative life outcomes. Evidence-based interventions for children and adolescents who are at-risk or who are displaying significant levels of impulsive behavior are necessary in order to promote self-control, and in turn, positive life outcomes. This study investigated the impact of an eight-week, school-based GCBT intervention on cognitive inhibition and behavioral impulsivity in adolescent participants. The intention of the study was to evaluate the trend in inhibition and impulsivity from baseline to post-intervention assessments across five middle school students dually enrolled in a residential treatment facility and a center-based emotional support …

Neurocognitive Patterns, Symptom Clusters, And Premorbid Factors That Predict Protracted Recovery From Concussion In Females, Sarah Pulaski

PCOM Psychology Dissertations

Concussion is an increasingly diagnosed injury that affects individuals of all ages. Although the underlying cause is unknown, research has demonstrated that females who sustain a concussion experience longer recoveries. Existing research has documented a relationship between age, gender, post-concussive headache and mental health conditions, and recovery; however, limited research has investigated the relationship between premorbid clinical variables and recovery. Research on post-injury neurocognitive declines and recovery has also demonstrated varied findings. Moreover, dizziness has been identified as significantly predictive of prolonged recovery, but no studies have investigated the effect of premorbid headache conditions on the development of dizziness. The …

Post Traumatic Stress Disorder Symptoms And Intimate Relationships Of Female Survivors Of Sexual Assault: The Effects Of Treatment With Prolonged Exposure, Group, And Supportive Counseling Therapy, Gabrielle Rhoads

PCOM Psychology Dissertations

Theory and research suggest that post traumatic stress disorder (PTSD) symptoms may disrupt intimate relationships of survivors of trauma. Nevertheless, little empirical research has examined the role of PTSD and how it affects intimate relationships of survivors of sexual assault. This study utilized selected measures to examine the degree to which symptoms and treatment(s) for PTSD contribute to relationship satisfaction in female survivors of sexual assault. Overall, the severity of PTSD predicted relationship maladjustment at baseline, which is consistent with past research findings. More specifically, avoidance and arousal were found to be the most robust predictors of relationship maladjustment. This …

Cytotoxic Effects Of Various Lactic Acid Bacteria On Caco-2 Cells, Sevda Er, Ayşe Tansu Koparal, Meri̇h Kivanç

Turkish Journal of Biology

Probiotics are live microbial food supplements that can be considered a functional food. They benefit the health of a host animal by maintaining their intestinal microbial balance. Most probiotic microorganisms are lactic acid bacteria (LAB) such as Lactobacillus spp., Bifidobacterium spp., and Enterococcus spp. LAB have been reported to possess certain anticancer properties. The vast majority of studies on their anticancer effects have dealt with colorectal cancers, although there have also been some studies on breast and bladder cancers. Colon cancer is the fourth most common cause of cancer-related mortality in the world. The aim of this study was to …

Identification And Pathogenicity Of Bacteria In The Mediterranean Corn Borer Sesamia Nonagrioides Lefebvre (Lepidoptera: Noctuidae), Ardahan Eski̇, Fi̇li̇z Özkan Çakici, Mustafa Güllü, Hacer Muratoğlu, Zi̇hni̇ Demi̇rbağ, İsmai̇l Demi̇r

Turkish Journal of Biology

Sesamia nonagrioides (Lep.: Noctuidae) is one of the most serious pests of corn in Turkey and other Mediterranean countries. Although various cultural, chemical, and biological methods are used to control this pest, its damage still continues in all Mediterranean countries. In this study, to find an effective bacterium that can be used as a biocontrol agent against S. nonagrioides, we isolated 15 bacteria from S. nonagrioides larvae and evaluated the larvicidal potency of all isolates on the pest. According to their morphological, physiological, biochemical, and molecular properties, the isolates were identified as Achromobacter insolitus (Sn1), Morganella morganii (Sn2), Klebsiella pneumoniae …

Genotoxicity Of Metaphase-Arresting Methods In Barley, Aslihan Temel, Nermi̇n Gözükirmizi

Turkish Journal of Biology

Amiprophos-methyl (APM) and colchicine (COL) are therapeutic agents and are also used in plant science. Cell cycle synchronization (CCS) is mediated by hydroxyurea (HU) and APM. The genotoxic effects of APM are unclear. In order to assess the genotoxicity of APM separately and with HU and then compare it with COL, we treated 2-day-old barley (Hordeum vulgare 'Bornova-92') seedlings with 8 µM APM for 2 h, 1.25 mM COL for 18 h, or 1.25 mM HU for 18 h and 4 µM APM for 2 h, with a final ice-cold water incubation. Following treatment, seedlings were recovered without any substance …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

Antioxidant Activity Of Heme Oxygenase 1 In Brassica Juncea (L.) Czern.(Indian Mustard) Under Salt Stress, Khushbu Verma, Shubham Dixit, Gyan Singh Shekhawat, Afroz Alam

Turkish Journal of Biology

Antioxidant enzymes play a protective role in plants under oxidative stress. The present study explores the role of antioxidant system heme oxygenase1 (HO1) in Brassica juncea (L.) Czern. in salt stress conditions. B. juncea seedlings were treated with different NaCl concentrations (0-200 mM) for 5 days. Salt stress elicited the highest response at 150 mM NaCl concentration; at this level, gene expression of HO1 was also upregulated. Apart from HO1, ascorbate peroxidase (APX), peroxidase (POD), and glutathione reductase (GR) also showed their highest activity at 150 mM NaCl concentration. The study shows that HO1 is indispensable in B. juncea for …

S. Cerevisiae $\Beta$-Glucan Reduced Viability Of Mouse Hepatoma Cells In Vitro, Artur Javmen, Ausra Nemeikaite-Ceniene, Saulius Grigiskis, Irena Jonauskiene, Mark Rudenkov, Darius Kacianauskas, Mykolas Mauricas

Turkish Journal of Biology

$\beta$-Glucan is a natural polymer, which is widely studied due to its multiple immunomodulatory properties. In addition, recent findings indicate potent antitumor properties of $\beta$-glucan. Saccharomyces cerevisiae, baker's yeast, is one of the commonly used sources of $\beta$-1,3-glucan. The aim of this work was to investigate S. cerevisiae $\beta$-glucan immunomodulatory activity against cancer cells.In our experiments, BALB/c mice were fed with insoluble whole $\beta$-glucan particles, and then their blood was collected for experiments. MH-22a hepatoma cells were treated with the blood of mice fed with $\beta$-glucan, and tumor cell viability was investigated after the treatment.The obtained results demonstrated that leukocytes …

Optimization Of Multiplex Rt-Pcr For M1, M23, And M23x Splice Variants Of Aqp4 And Ss-Actin Transcripts In Dalton?S Lymphoma Mouse Tissues, Rajaneesh Kumar Gupta, Sukala Prasad

Turkish Journal of Biology

Multiplex reverse transcriptase-polymerase chain reaction (MRT-PCR) is a method of choice for efficient and simultaneous analysis of gene expression at the transcript level with limited amounts of tissues; however, it is less common than other methods due to certain limitations. Here, we describe the protocol for MRT-PCR-based semiquantitative analysis of all AQP4 transcripts simultaneously in Dalton's lymphoma (DL) using transcript-specific primers and outline the critical parameters. Aquaporin-4 (AQP4) water channels are associated with edema of tissues due to various diseases. The AQP4 transcript possesses alternative transcription initiation sites and produces three isoforms, AQP4.M1, AQP4.M23, and AQP4.M23X, which constitute heterotetrameric orthogonal …

Use Of In Vitro Propagation Of `Obla?Inska? Sour Cherry In Rootstock Breeding, Dusica Doric, Vladislav Ognjanov, Goran Barac, Mirjana Ljubojevic, Ankica Pranjic, Krunoslav Dugalic, Sezai̇ Erci̇şli̇

Turkish Journal of Biology

Prunus cerasus L. `Obla?inska? sour cherry germplasm was established in vitrodirectly from in situ plants on different explant collection dates, enabling quick clonal multiplication and introduction to a rootstock breeding program. Rosette initiation of four investigated genotypes was possible from November to April on the medium containing Schenk and Hildebrandt (SH) macroelements, Murashige and Skoog (MS) microelements, and vitamins supplemented with (in mg L?1) 6-benzyladenine (BA), 0.5; indole-3-butyric acid (IBA), 0.01; gibberellic acid (GA3), 0.1; citric acid, 10; and L-ascorbic acid, 10. The lowest percent of contamination was noted in November and December, when dormant buds were used as an …

Storage Temperature Of Boar Semen And Its Relationship To Changes In Sperm Plasma Membrane Integrity, Mitochondrial Membrane Potential, And Oxidoreductive Capability, Dariusz Gaczarzewicz, Jan Udala, Malgorzata Piasecka, Barbara Blaszczyk, Tomasz Stankiewicz

Turkish Journal of Biology

The aim of this study was to analyze changes in sperm plasma membrane integrity, mitochondrial activity, and extracellular environment during storage of boar semen at 5 °C, 16 °C, and 25 °C for 10 days. Progressive sperm motility, plasma membrane integrity (SYBR-14/PI-test and HOS test), aspartate aminotransferase (AAT), and mitochondrial activity (JC-1-test and NADH-dependent NBT assay), as well as pH and osmolality were assessed in nine ejaculates of Polish Landrace boars. The plasma membrane integrity of the semen stored at 5 °C was similar to that of the semen stored at 16 °C and 25 °C; however, an increase in …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

Role Of Melatonin On Calcium Signaling And Mitochondrial Oxidativestress In Epilepsy: Focus On Trp Channels, Mustafa Naziroğlu

Turkish Journal of Biology

Calcium ion (Ca2+) accumulation and excessive oxidative stress in the hippocampus and brain cortex have long been known as major contributors to the etiology of epilepsy. I have reviewed the role of Ca2+ signaling through cation channels and mitochondria-mediated oxidative stress on epilepsy in human and animals. A review of the relevant papers and results from recent studies were obtained from PubMed and the Science Citation Index. Current literature findings indicate that melatonin and agomelatine reduce activation of hippocampal transient receptor potential (TRP), glutamate receptors, and voltage-gated calcium channels that are critical for the development of abnormal Ca2+ homeostasis and …

Melatonin As A Stabilizer Of Mitochondrial Function: Role In Diseases And Aging, Cristina Carrasco, Ana B. Rodriguez, Jose A. Pariente

Turkish Journal of Biology

It is now almost 60 years since the discovery of melatonin and new physiological functions of the indole continuously appear in the most recent studies worldwide. Experimental evidence emphasizes its importance as a stabilizer of the mitochondrial bioenergetics, which could be related to the prevention of development of aging and several diseases. In the next years, conscientious investigation about this topic should be undertaken by scientists of different research areas to achieve a better understanding of the molecular mechanisms implied. This will ultimately allow the development and clinical application of efficacious treatments.

Prooxidant Effects Of Melatonin: A Brief Review, Malwina S. Munik, Cem Ekmekçi̇oğlu

Turkish Journal of Biology

Melatonin acts classically through the widely expressed G protein-coupled membrane receptors MT1 and MT2, respectively. The functional role of the MT receptors is not fully clear with multiple effects, such as effects on the circadian, reproductive, immune, cardiovascular, and intestinal systems, being suggested. In addition to receptor-mediated effects, melatonin also acts as a potent antioxidant and it is quite evident that melatonin and its metabolites efficiently reduce oxidative damage to proteins, lipids, and DNA and also exert protective effects on mitochondria. The potent antioxidant activity of melatonin stems from various complex mechanisms, including direct scavenging of radicals, stimulation of antioxidant …

Amelioration Of Subchronic Acrylamide Toxicity In Large Intestine Of Rats Byorganic Dried Apricot Intake, Mehmet Erman Erdemli̇, Zümrüt Doğan, Yilmaz Çi̇ğremi̇ş, Müslüm Akgöz, Eyüp Altinöz, Murat Geçer, Yusuf Türköz

Turkish Journal of Biology

Acrylamide (AA) has neurotoxic, mutagenic, and genotoxic effects in humans and experimental animals. Fruit consumption is important for human health, because fruits are the source of many nutrients such as vitamins, minerals, carotenoids, dietary fiber, and phytonutrients. Many agricultural products provide natural melatonin in the diet. At the onset of the study, rats were weighted and randomly divided into four groups each containing 10 rats as follows: group 1: control (fed with normal diet and normal drinking water); group 2: apricot (fed with a daily diet with 5% apricot and normal drinking water); group 3: AA (administered daily acrylamide at …

The Effects Of Agomelatine And Melatonin On Ecog Activity Of Absenceepilepsy Model In Wag/Rij Rats, Hati̇ce Aygün, Duygu Aydin, Sema İnanir, Fati̇h Eki̇ci̇, Mustafa Ayyildiz, Erdal Ağar

Turkish Journal of Biology

The aim of this study was to evaluate the effect of the melatonergic M1 and M2 receptor agonist and serotonergic 5-HT2C receptor antagonist agomelatine on the spike wave discharges (SWDs) seen in electrocorticographic (ECoG) recordings of WAG/Rij rats with absence epilepsy. Twenty-one WAG/Rij male rats were used in this study. Tripolar electrodes were placed on skulls and control ECoG activities were recorded. Experimental groups received normal saline (Group I: 1 mL, intraperitoneally (i.p)), agomelatine (Group II: 40 mg/kg, i.p), and melatonin (Group III: 40 mg/kg, i.p) injections for 7 days. Following this period, 2-h ECoG recordings were repeated. The number …

Melatonin Is A Potent Modulator Of Antioxidative Defense And Cellular Proliferation Against Aluminum Toxicity In Rats, Ni̇hal Ömür Bulan, Guner Sarikaya-Unal, Sevim Tunali, Pelin Arda Pi̇ri̇nççi̇, Refiye Yanardag

Turkish Journal of Biology

Aluminum is the most abundant metal on earth, known for its toxicity to humans and laboratory animals. Melatonin, produced by the pineal gland, has been shown to be an effective antioxidant. In this study, we investigated the possible protective role of melatonin in modulating toxicity and oxidative stress induced by chronic exposure to aluminum in the small intestine of rats. Wistar albino rats were divided into five groups. Group I served as the control and received only physiological saline, Group II served as the control for the melatonin group and received ethanol and physiological saline, Group III received melatonin, Group …

Melatonin Increased Vitamin C And Antioxidant Enzyme Values In The Plasma,Heart, Liver, And Kidney Of Adriamycin-Treated Rats, Ali̇ Zi̇ya Karakilçik, Muharrem Bi̇ti̇ren, Mustafa Zeri̇n, Haki̇m Çeli̇k, Nurten Aksoy

Turkish Journal of Biology

Adriamycin, an anticarcinogenic agent, causes excessive production of reactive oxygen species (ROS). These radicals may affect antioxidant defense systems. The present study was designed to investigate the effects of melatonin on antioxidant enzyme activities and vitamin C in Adriamycin-treated rats. In the current study, rats were divided into three groups: control, Adriamycin, and melatonin+Adriamycin groups. The control group was intraperitoneally injected physiological saline (0.9%) as a placebo. The Adriamycin and melatonin+Adriamycin groups were administered Adriamycin (25 mg/kg body weight). The melatonin+Adriamycin group was pretreated with melatonin (0.5 mg/kg body weight). Vitamin C concentration and catalase (CAT), superoxide dismutase (SOD), glutathione …

Dna Protective And Antioxidative Effects Of Melatonin In Streptozotocin-Induced Diabetic Rats, Seli̇m Sekki̇n, Eda Duygu İpek, Murat Boyacioğlu, Cavi̇t Kum, Ümi̇t Karademi̇r, Hande Sultan Yalinkilinç, Mehmet Onur Ak, Hulki̇ Başaloğlu

Turkish Journal of Biology

Diabetes mellitus is a chronic disease characterized by elevated blood sugar levels. In diabetic patients, oxidative stress induced by the presence of excessive free radicals is closely associated with chronic in?ammation, leading to potential tissue damage. Melatonin (MEL) is a compound synthesized by the pineal gland and a scavenger of free radicals. The aim of this study was to research the effects of MEL on oxidative stress and its DNA protective effects in streptozotocin-induced diabetic rats. In total, 32 rats were equally divided into four experimental groups: control, melatonin, diabetic, and diabetic + melatonin. A single dose of streptozotocin (60 …

Effects Of Photoperiod Variations And Alpha-Lipoic Acid Treatment On Melatonin,Cortisol, And Oxidative Stress Levels In The Blood Of Rats, Cahi̇de Çevi̇k, Recep Aslan

Turkish Journal of Biology

This study aimed to investigate the effects of frequently changing photoperiods and alpha-lipoic acid treatment on melatonin, cortisol, oxidative markers, and some blood parameters. Eighty-four rats were randomly and equally divided into 7 groups: a control group, 3 prolonged light groups, and 3 prolonged dark groups. The study was completed in 2 stages, with 1- and 4-week periods, respectively. Blood samples were obtained at the end of the first and fourth weeks, and at the end of the dark period for the first and second stages. Serum aspartate aminotransferase and creatinine levels were significantly elevated in the prolonged dark olive …

Cover And Contents

Turkish Journal of Biology

No abstract provided.

A Comprehensive Method For Tuning And Pedaling Timpani, Brandon M. Arvay

Theses and Dissertations--Music

Method books are an integral part of the percussion pedagogy. Because of the vast number of instruments a modern percussionist is expected to play, they often look for progressive, concise, and effective resources that can make learning such a variety of instruments more efficient. Instructional books currently exist for many areas of percussion performance, including snare drum, mallet percussion, timpani, World music, accessories, and marching percussion. Included in these books are information and procedures on music reading, rhythm studies, listening skills, part preparation, and technical approach. Focusing on timpani methods specifically, many of these books include tuning and pedaling exercises …

Interdisciplinary Collaboration With Music Therapy During Routine Pediatric Dental Procedures, Austin S. Robinson

Theses and Dissertations--Music

The incorporation of integrative medicine into traditional treatment options has steadily increased during the past two decades. This has resulted in a change in the dynamics of interdisciplinary teams creating the need to better understand the roles and responsibilities of team members. The purpose of this study was to examine the perceptions of dental treatment team members regarding the role and responsibilities of music therapy during treatment.

A total of 10 participants were included in this study. Participants completed a pre-music therapy survey to establish prior knowledge, experience with, and perceptions of music therapy. Following an experiential intervention, participants completed …

The Harm Principle At Play: How The Animal Welfare Act Fails To Protect Animals Adequately, Proshanti Banerjee

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.

Toward A Heterodox Property Law And Economics, Lua Kamal Yuille

Texas A&M Law Review

Property law is profoundly unsatisfying. This statement is not meant to suggest that property is wrong or bad. Nor does it mean to take issue with any particular rule of property law, at least in a way that is not already reflected in the rich property literature. Rather, property law is unsatisfying because, often, its settlements and compromises seem wanting and iniquitous, even while envisioned alternatives seem untenable and unfair. Indeed, the standard first-year Property syllabus reads like a compendium of the Catch-22.

Introduction To The Symposium Edition: New Technology And Old Law: Rethinking National Security, Lisa A. Rich

Texas A&M Law Review

Introduction to the Symposium Edition: New Technology and Old Law: Rethinking National Security

Emerging Biotechnologies And The 1972 Biological Weapons Convention: Can It Keep Up With The Biotechnology Revolution?, Victoria Sutton

Texas A&M Law Review

In light of the quandaries presented by domestic law, has the Biological Weapons Convention of 1972 (“BWC”) also been so outpaced by the technologies that it is no longer effective and meaningful in international law? Part II will examine the continuum of official actions that have attempted to keep pace with the growing biotechnologies that may present threats to global biosecurity through interpreting the BWC. Part III looks at how these definitions may not be sufficient. Finally, Part IV looks at other mechanisms that may provide a better way of controlling biological weapons than redefining the technologies through the current …