Digital Commons Network^™

Nerve Growth Factor Reduces Apoptotic Cell Death In Rat Facial Motor Neurons After Facial Nerve Injury, Lian Hui, Jing Yuan, Zhong Ren, Xuejun Jiang

Neurosciences

Objectives: To assess the effects of nerve growth factor (NGF) on motor neurons after induction of a facial nerve lesion, and to compare the effects of different routes of NGF injection on motor neuron survival. Methods: This study was carried out in the Department of Otolaryngology Head & Neck Surgery, China Medical University, Liaoning, China from October 2012 to March 2013. Male Wistar rats (n = 65) were randomly assigned into 4 groups: A) healthy controls; B) facial nerve lesion model + normal saline injection; C) facial nerve lesion model + NGF injection through the stylomastoid foramen; D) facial nerve …

Potential Neuroprotective Effect Of Anakinra In Spinal Cord Injury In An In Vivo Experimental Animal Model, Askin E. Hasturk, Erdal R. Yilmaz, Erhan Turkoglu, Murat Arikan, Guray Togral, Nazli Hayirli, Berrin I. Erguder, Oya Evirgen

Neurosciences

Objective: To evaluate the therapeutic effects of inhibiting interleukin-1 beta (IL-1β) in vivo using Anakinra in an experimental model of spinal cord injury (SCI). Methods: All experimental procedures were performed in the animal laboratory of Ankara Education and Research Hospital, Ankara, Turkey between August 2012 and May 2014. The SCI was induced by applying vascular clips to the dura via a 4-level T5-T8 laminectomy. Fifty-four rats were randomized into the following groups: controls (n = 18), SCI + saline (n = 18), and SCI + Anakinra (n = 18). Spinal cord samples were obtained from animals in both SCI groups …

Update In Vitamin D And Multiple Sclerosis, Fatimah M. Alharbi

Neurosciences

Multiple sclerosis (MS) is a common neurological disease, and its etiology remains unknown. In recent years, increasing attention has been paid to the possible association between MS and vitamin D deficiency. Here, we review the current literature between MS and vitamin D, showing clear evidence that vitamin D deficiency is a risk factor for MS despite the lack of direct evidence for the effects of vitamin D in MS progression.

Advanced Case Of Glioblastoma Multiforme And Pregnancy: An Ethical Dilemma, Intisar M. Al-Rasheedy, Fahad M. Al-Hameed

Neurosciences

Glioblastoma multiforme (GBM) is the most common and malignant form of the glial tumors. Advanced and treated GBM is rarely associated with pregnancy for many reasons. Glioblastoma multiforme presenting during pregnancy carries unique challenges to the patient, baby, family, and health care providers. We describe an unusual case of advanced GBM that was treated with maximum doses of chemotherapy and radiations, and she became pregnant and presented at eighteenth weeks of gestation. Her medical management was associated with a significant ethical dilemma. We managed to deliver the baby safely through cesarean section at week 28 despite the critical condition of …

Pathophysiology Of Carpal Tunnel Syndrome, Moutasem S. Aboonq

Neurosciences

Carpal tunnel syndrome (CTS) is the most common median nerve neuropathy, accounting for 90% of all neuropathies. Carpal tunnel syndrome presents in 3.8% of the general population, with a higher prevalence among women. There are several risk factors associated with CTS, including both medical and non medical factors. The pathophysiologic mechanisms involved in the median nerve compression and traction are thought to be complex, and as yet are not fully understood. The present review aimed to provide an overview of the pathophysiology of median nerve neuropathy in the carpal tunnel, and subsequent development of CTS.

Clinical Features Of Epilepsy At 2 Referral Hospitals In Northern Iran, Mahdi Rezaeian Yazdi, Morteza Mazloum Farsi Baf, Atena Afsari, Afrouz Alipour, Mostafa Khorashadizadeh, Peyman Khajeh Ghiassi, Seyed Mehran Homam

Neurosciences

Objective: To investigate the demographic and clinical characteristics of epilepsy in 2 referral hospitals in northern Iran. Methods: In this cross-sectional study, we evaluated 300 patients with the confirmed diagnosis of epilepsy referred to the Neurology clinics of 22-Bahman, and 17-Shahrivar Hospitals, Mashad, Iran, from April 2011 to December 2012. We collected and analyzed demographic and disease information. Results: The mean age of patients was 31.5 ± 15.3 years. The diagnosis of disease had been made approximately 10 months after the onset of symptoms, and the treatment gap was 28%. The most widely used anticonvulsants were sodium valproate, carbamazepine, and …

Maternal Knowledge Of Acute Seizures, Nawal A. Asiri, Mohammed A. Bin Joubah, Samar M. Khan, Mohammed M. Jan

Neurosciences

Objective: To study maternal knowledge -of, and behavior during acute seizures. Methods: A cross sectional study conducted from September 2013 to January 2014 included consecutive mothers presenting at the Pediatric Neurology Clinics of King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia. A structured 30-item questionnaire was designed to examine their demographics, knowledge, and behavior on acute seizures. Results: A total of 92 mothers were interviewed and 41% witnessed at least one acute seizure in their affected child (range 1-15 years, mean 4.5). Up to 26% felt not knowledgeable at all regarding the acute care and management of seizure. Mothers …

Design And Comparison Of Immersive Interactive Learning And Instructional Techniques For 3d Virtual Laboratories, Shuo Ren, Frederic D. Mckenzie, Sushil K. Chaturvedi, Ramamurthy Prabhakaran, Jaewan Yoon, Petros J. Katsioloudis, Hector Garcia

Computational Modeling & Simulation Engineering Faculty Publications

This work presents the design, development, and testing of 3D virtual laboratories for practice, specifically in undergraduate mechanical engineering laboratories. The 3D virtual laboratories, implemented under two virtual environments3DTV and Computer Automated Virtual Environment (CAVE)serve as pre-lab sessions performed before the actual physical laboratory experiment. The current study compares the influence of two instructional methods (conventional lecture-based and inquiry-based) under two virtual environments, and the results are compared with the pre-lab sessions using a traditional paper-based lab manual. Subsequently, the evaluation is done by conducting performance and quantitative assessments from students pre-and post-laboratory performances. The research results demonstrate that students …

Longwood University Catalog 2015-2016, Longwood University

Undergraduate Catalogs

No abstract provided.

The Multilevel Marketing Misnomer: How The Federal Trade Commission May Change Network Marketing, Jeremy Pineres

Emory Business Law Review Perspectives

In light of recent litigation against Vemma Nutrition Co. by the Federal Trade Commission, Jeremy Pineres examines the compensation structures of multi-level marketing companies with a focus on the various shortcomings of these companies that lead to quasi-pyramid scheme business practices. During a time where the internet provides consumers instant access to competitive pricing, multi-level marketing companies nevertheless offer products and services that are largely unsellable. Generally, the price and quality of these marketed products and services are unable to compete with store-bought items. When combined with a compensation structure that financially rewards and encourages new member recruitment over bona …

Prevalence Of Schistosoma Haematobium Infection Among School-Age Children In Afar Area, Northeastern Ethiopia, Abraham Degarege, Zeleke Mekonnen, Bruno Levecke, Mengistu Legesse, Yohannes Negash, Jozef Vercruysse, Berhanu Erko

Journal Articles: Epidemiology

In this study, the prevalence and intensity of Schistosoma haematobium infection was determined among school-age children living in the Middle and Lower Awash Valley, Afar Regional State of Ethiopia. Between February and May 2014, urine samples were collected from 885 school-age children (5-16 years of age) from the Middle (n = 632; 4 villages) and Lower (n = 253; 3 villages) Awash Valley. All samples were processed using urine filtration to detect and quantify S. haematobium eggs. In addition, a subset of the urine samples was tested for hematuria using a urine dipstick (n = 556). The overall prevalence was …

Tennessee Ag Insider, A Guide The The State's Farms, Food, And Forestry, 2015 Edition, Tennessee. Department Of Agriculture.

Tennessee Ag Insider

No abstract provided.

No. 18, The Algood Sr-42 Project, Report On Phase Ii Excavations In Putnam County, Tennessee, Sarah A. Levithol, Tennessee. Department Of Environment & Conservation.

Archaeology – Investigations

No abstract provided.

No. 19, The Riverbend Prison Site (40dv83), A Late Archaic And Early Woodland Camp Along The Cumberland River In Davidson County, Tennessee, Aaron Deter-Wolf, Tennessee. Department Of Environment & Conservation.

Archaeology – Investigations

No abstract provided.

Child Fatalities In Tennessee Review Of 2013 Deaths, Understanding And Preventing Child Deaths, Tennessee. Department Of Health.

Child Fatalities in Tennessee Report

No abstract provided.

The Association Between Environmental Cadmium Exposure And All-Cause Mortality And Cardiovascular Disease In A Cohort Of Elderly Western Australian Women, Kane Deering

Theses : Honours

Introduction: Recent research suggests an association between environmental cadmium exposure and increased risk of, and death from, cardiovascular disease, the number one cause of mortality in Australia and worldwide. However, the research to date is neither comprehensive nor have there been any studies conducted on an Australian population. This study identified whether increasing concentrations of urinary cadmium in elderly West Australian women was associated with an increased odds of incidence of, and deaths from CVD, as well as all-cause mortality.

Method: Cadmium excretion was measured in urine samples collected at baseline (1998) from 1359 women from Perth who …

Design Of Novel Histone Demethylase Inhibitors As Drug Candidates To Prevent Cardiac Ischemia-Reperfusion Injury, Craig Jerome Kutz

MUSC Theses and Dissertations

Current therapies to assist short- and long-term outcomes after acute myocardial infarction (AMI) depend on primary percutaneous coronary intervention shortly after ischemic insult. Upon reperfusion, localized influx of oxidative stressors overwhelms the endogenous antioxidant systems and lead to contractile dysfunction and arrhythmias. The extent of irreversible myocyte damage during ischemia-reperfusion (IR) injury is a key determinant in patient outcomes and therefore, strategies to reduce oxidative damage are essential. In recent years, increasing evidence indicates that epigenetic enzymes such as the histone demethylases and deacetylases play crucial roles during cardiovascular disease (CVD). One such enzyme, lysine specific demethylase-1 (LSD1), is hypoxia-inducible …

Role Of 2,4-Dihydroxyquinoline (Dhq) In Pseudomonas Aeruginosa Pathogenicity, Jordan Dale Gruber

MUSC Theses and Dissertations

Bacterial group behaviors are advantageous during an infection to thwart immune cell attack and resist deleterious changes in the environment. Bacteria use a chemical messaging system in order to coordinate the phenotypes in the environment. In Pseudomonas aeruginosa, the Pseudomonas quinolone signal (Pqs) quorum-sensing system produces alkylquinolones that regulate virulence factor production and also perform extracellular roles. Two alkylquinolones, 2-heptyl-4-quinolone (HHQ) and 2- heptyl-3-hydroxy-4-quinolone (PQS) activate transcriptional regulator PqsR for subsequent production of quinolones and phenazines, iron chelation, and autolysis. The most abundant quinolone produced from the Pqs system is 2,4-Dihydroxyquinoline (DHQ); however, DHQ has no known function. We demonstrated …

Developing A Heterotypic Cell Culture Model To Determine Vegf Action Of Neural Stem Cell Fate Choice, Stephanie Snyder

Theses and Dissertations

Brain development requires tight cell and molecular regulation for proper neural stem cell (NSC) proliferation and differentiation. Increasing interest in NSCs has arisen due to the flexibility inherent within their proliferative capacity and their ability to generate multiple neuronal cell types. Our main focus is on the cortex, the primary integrator for higher order brain function. Cortical NSC proliferation and differentiation occur in concert with blood vessel ingression into the primitive cortex to vascularize the neuroepithelium. One potential influence derived from vascular cells is Vascular endothelial growth factor A (Vegf). Vegf has the ability to regulate both neurogenesis and angiogenesis …

The Tragedy Of The Vital Commons, M. Alexander Pearl

Faculty Articles

The concept of the Tragedy of the Commons is well known, but it does not adequately capture the gravity of harm caused by the mismanagement of certain common pool resources (CPR). Not all commons are created equal; some are more important than others. If the common pasture where cows graze is overused and rendered barren, the community shifts to a vegan diet. But, if the groundwater aquifer used to grow soybeans and other foods is exhausted and no water remains for extraction, then individuals, families, and entire communities perish. Present commons scholarship is unable to differentiate between varying levels of …

Energy Access For The "Powerless": The Role Of Relational Connectivity Between Entrepreneurs And Private Capital Investors, Michael E. Desa

Student Scholarship

Although $1.6 trillion was invested in 2013 in global energy, of which $254 billion was in renewable energy, small power producer (SPP) entrepreneurs that focused their operations on the 1.4 billion powerless populations received a trifling $2.2 billion--less than $2 per person and 1.37% of overall investment. Prevailing research details policy methods, finance mechanisms, and business models intended to attract private capital and enlarge energy access; however, the nominal investment levels signify that private capital remains uninterested. This qualitative study used a grounded theory approach to discover the role of interaction experiences between SPP entrepreneurs and investors and the factors …

Supplementing Cow-Calf Pairs Grazing Smooth Bromegrass, Jason M. Warner, Annie J. Doerr, Galen E. Erickson Erickson, Rick J. Rasby, Terry J. Klopfenstein

Nebraska Beef Cattle Reports

A three-year study evaluated supplementing ethanol co-products mixed with low-quality forage to cow-calf pairs grazing smooth bromegrass as a method to replace grazed forage intake. Supplementing a 30:70 modified distillers grains plus solubles:cornstalks mixture reduced estimated grazed forage intake by approximately 40%. Doubling the stocking rate and supplementing did not impact cow or calf performance. A summer supplementation program designed to reduce grazed forage intake is a viable strategy for increasing stocking rate if forage for grazing is limited.

Effect Of Post-Weaning Management And Age At Weaning On Calf Growing And Finishing Performance, Jason M. Warner, Curtis J. Bittner, Karla H. Jenkins Jenkins, Rick J. Rasby, Terry J. Klopfenstein, Galen E. Erickson

Nebraska Beef Cattle Reports

The impact of post-weaning management system and calf age at weaning on growing and finishing performance was evaluated. During the growing phase, cattle in the fast-track system had improved intake, gain, and feed conversion. Although initial finishing weight was similar between systems, slow-track cattle had greater intake, gain, final body weight, and carcass weight. While the impact of age at weaning was negligible, the improvement in finishing performance for slow-track cattle demonstrates the value of different management systems.

Statistics Used In The Nebraska Beef Report And Their Purpose

Nebraska Beef Cattle Reports

The purpose of beef cattle and beef product research at University of Nebraska–Lincoln is to provide reference information that represents the various populations (cows, calves, heifers, feeders, carcasses, retail products, etc.) of beef production. Obviously, the researcher cannot apply treatments to every member of a population; therefore, he/she must sample the population. The use of statistics allows the researcher and readers of the Nebraska Beef Report the opportunity to evaluate separation of random (chance) occurrences and real biological effects of a treatment. Following is a brief description of the majorstatistics used in the beef report. For a more detailed description …

Estimation Of British- And Continental-Specific Heterosis Effects For Birth, Weaning, And Yearling Weight In Cattle, Lauren N. Schiermiester, R. Mark Thallman, Larry A. Kuehn Kuehn, Matthew L. Spangler

Nebraska Beef Cattle Reports

Heterosis, assumed proportional to expected breed heterozygosity, was calculated for 6,834 individuals with birth, weaning, and yearling weight records from Cycle VII of the U.S. Meat Animal Research Center Germplasm Evaluation Program. Heterosis was further estimated by proportions of British x British (BxB), British x Continental (BxC), and Continental x Continental (CxC) crosses. Estimates of BxB, BxC, and CxC heterosis were significant for weaning and yearling weight. This study illustrated that differences among biological types exist and provide an opportunity to utilize specific breeds and exploit heterosis in a crossbreeding system to achieve production goals.

The Effects Of Source And Amount Of Nitrite On Quality Characteristics Of All-Beef Frankfurters, Eric Miller, Chad G. Bower, Amy L. Redfield Redfield, Gary A. Sullivan

Nebraska Beef Cattle Reports

In an effort to meet consumers’ demand for foods with more natural ingredients, processors have begun manufacturing meat products cured with natural nitrite sources. The objective of this study was to evaluate the quality characteristics of all-beef frankfurters cured with traditional or alternative sources of nitrite and using equivalent amounts of nitrite. Frankfurters cured with alternative sources of nitrite had a slightly darker, less red exterior and slightly more yellow interior than those containing sodium nitrite. No differences were observed for pH or water activity. Both curing methods can be used to manufacture all-beef frankfurters with similar characteristics when using …

Stocking Rate Effects On Forage Nutrient Composition In Early Summer Pastures, Jared V. Judy, Jacki A. Musgrave, L. Aaron Stalker Stalker, K. H. Jenkins, Terry J. Klopfenstein

Nebraska Beef Cattle Reports

Nebraska Sandhills upland range pastures were used to measure the effectsof stocking rate on forage nutrient content in early summer pastures. Stocked pastures had lower CP, in vitroorganic matter digestibility, forage availability, and higher NDF compared with ungrazed pastures. Clipped samples of current year growth had greater CP and in vitro organic matter digestibility than diet samples. Observed results indicate early season grazing decreasesdiet nutrient content and forage availability compared with ungrazed pastures, suggesting that cattle were consuming both current and previous year growth.

Comparison Of Commercial Lick Tubs To Distillers Grains Supplementation For Calves Grazing Corn Residue, Mandi Jones, James C. Macdonald, Galen E. Erickson Erickson, Terry J. Klopfenstein, Kathleen R. Brooks, Dirk B. Burken, Robby Bondurant, Andrea K. Watson

Nebraska Beef Cattle Reports

Steer calves grazing irrigated corn residue were supplemented dried distillers grains plus solubles (DGS) or allowedcontinuous access to a commercial lick tub. Dried DGS was fed at 2.94 lb/steer/day and the lick tubs were consumed at 2.04 lb/steer/day (DM basis). Gain was greater for cattle supplemented with dried DGS (1.36 lb/day) compared to those with access to lick tubs (0.83 lb/day). Supplement efficiency varied between calves receiving dried DGS (46%) and those with continuous access to the lick tub (43%) when expressed on a DM basis. Values for dried DGS supplementation (48%) were not different for supplement efficiencyon an OM …

Nutrient Digestibility And Ruminal Ph Of Finishing Diets Containing Dry Milling Byproducts With And Without Oil Extraction, Melissa L. Jolly-Breithaupt, Adam L. Shreck, Jana L. Harding Harding, James C. Macdonald, Terry J. Klopfenstein, Galen E. Erickson

Nebraska Beef Cattle Reports

A metabolism trial was conducted to determine the effects of corn oil removal in condensed distillers solubles (CDS) and modified distillers grains plus solubles (MDGS) on nutrient digestibility and ruminal pH. Oil removal had no impact on DM, OM, or NDF digestibility in steers fed CDS or MDGS. However, steers fed de-oiled CDS had a lower fat digestibility than steers fed normal CDS. Average ruminal pH was lower for steers fed de-oiled MDGS than for steers fed normal MDGS, however no difference within CDS was observed.

Effect Of Distillers Grains Plus Solubles And Monensin Supplementation On Grazing Steers, Tyler L. Hasenauer, Terry J. Klopfenstein, James C. Macdonald Donald, Robby G. Bondurant, Dirk B. Burken

Nebraska Beef Cattle Reports

Yearling steers rotationally grazing smooth bromegrass were individually supplemented monensin at 0 or 200 mg with modified distillers grains plus solubles (MDGS) at .05, 0.4, 0.6, and 0.8% BW. Cannulated steers continuously grazing smooth bromegrass were assigned randomly to one of two treatments: 0.4% BW MDGS supplementation with 0 or 200 mg monensin. Monensin did not affect ADG of steers supplemented MDGS ≥ 0.4% BW. Steers supplemented with monensin had a decreasein estimated average forage intakefrom 16.16 lb to 14.75 lb/OM daily.