Digital Commons Network^™

Research Highlights (October–December 2015), Deepti Chalia

Indian Journal of Research in Homoeopathy

No abstract provided.

Republished: Sulphur Alters Nfκb-P300 Cross-Talk In Favour Of P53-P300 To Induce Apoptosis In Non-Small Cell Lung Carcinoma, Shilpi Saha, Bhattacharjee Pushpak, Deblina Guha, Kirti Kajal, Poulami Khan, Sreeparna Chakraborty, Shravanti Mukherjee, Shrutarshi Paul, Rajkumar Manchanda

Indian Journal of Research in Homoeopathy

Adverse side effects of chemotherapy during cancer treatment have shifted considerable focus towards therapies that are not only targeted but are also devoid of toxic side effects. We evaluated the antitumorigenic activity of sulphur, and delineated the molecular mechanisms underlying sulphurinduced apoptosis in non-small cell lung carcinoma (NSCLC) cells. A search for the underlying mechanism revealed that the choice between the two cellular processes, NFκBp65-mediated survival and p53-mediated apoptosis, was decided by the competition for a limited pool of transcriptional coactivator protein p300 in NSCLC cells. In contrast, sulphur inhibited otherwise upregulated survival signaling in NSCLC cells by perturbing the …

Metamorphoses After Oboe: An Examination Of The Evolution Of Oboe Part Writing Through Music History, Patrick Quinn

Theses and Dissertations

Throughout Western music history, the oboe has served as one of the primary members of the orchestra. From its beginnings in the Baroque consort to the modern day orchestra, the instrument's story is one of unique ups and downs between being a staple and being a necessity. Though the instrument has weathered much through Western music history, it has endured and evolved into the instrument that is so familiar today. What is not as familiar, however, is the progression the oboe took to get to its modern iteration. The modern oboe represents years of development, both technologically and musically, on …

Tennessee Birth Defects Registry Report 2008-2012, Tennessee. Department Of Health.

Tennessee Birth Defects

No abstract provided.

Structural And Functional Studies Of The Papain-Like Protease 2 From Mouse Hepatitis Virus, Yafang Chen

Open Access Dissertations

Our goal is to establish a system to investigate how the deubiquitinating (DUB) and deISGylating activities of coronavirus (CoV) papain-like protease domains (PLPs) are involved in virus immune evasion. To this end, we chose PLP2 from mouse hepatitis virus (MHV) as our target of study because MHV has historically served as a model system for the study of CoVs, and it has undeniable advantage of ease in culturing in comparison to human coronaviruses.

It is reported here the expression and purification of a region of MHV nsp3 that contains the catalytic core of the PLP2 domain and its neighboring domains. …

Overt And Covert Shandyism Of Nabokov's Nikolai Gogol, Margarit Ordukhanyan

CLCWeb: Comparative Literature and Culture

In her article "Overt and Covert Shandyism of Nabokov's Nikolai Gogol" Margarit Ordukhanyan examines Vladimir Nabokov's 1942 novel, an unusual biography of the nineteenth-century Russian author. Ordukhanyan discusses parallels between Nabokov's biography of Gogol and Laurence Sterne's Life and Opinions of Tristram Shandy. She highlights the direct allusions and textual references Nabokov makes to Sterne's novel and argues that Nabokov uses Tristram Shandy as the model for creating and interpreting his biography of Gogol by fictionalizing Gogol and portraying him as a Shandean character. Further, Ordukhanyan discusses how Nabokov uses Sterne's novel to undermine the genre of literary …

Neural Networks For Autonomous Control Of Unmanned Helicopters, Padraig M. Moriarty

Theses

Landing a helicopter on a ship in high seas can be a dangerous endeavour. This thesis proposes to examine the possible uses of Artificial Neural Networks (A.N.N.) in the aiding and/or the landing of an Unmanned Aerial Vehicle (U.A.V.). It proposes that this procedure can be segregated into three distinct phases. The data for the A.N.N. training and testing sets is generated through simulation in the Unity cross-platform game engine. Phase 1 is intended to convert video images from an on-board camera to a set of numeric outputs suitable for use in Phase 2. Phase 2 estimates the current relative …

From Kickoff To Handoff: Coaching Teens To Tackle Stem Literacy, Chad Ripberger, Lydia B. Blalock

Journal of Extension

This article discusses how intensive, content-rich, multiple-day conferences for teams of youth and their adult coaches can be used to initiate the training and planning needed for teens to successfully serve as STEM teachers. The concepts are based on three 4-H "teens as teachers" projects that included 29-36.5 hour initial training conferences. Teenagers (173) completed pre/post surveys on STEM knowledge, skills, careers, resources, and teaching ability. The teenagers exhibited increases in these areas for all three conferences. The authors discuss the common elements of these conferences, provide implementation examples and suggest resources that support this type of training.

Zoonotic Diseases—Fostering Awareness In Critical Audiences, David C. Van Metre, Paul S. Morely

Journal of Extension

Zoonotic diseases are infectious diseases that are shared between humans and other vertebrate animals. Extension professionals often serve as consultants and educators to individuals at high risk of zoonotic diseases, such as participants in 4-H livestock projects. Effective education about zoonotic diseases begins with an awareness of the multitude of challenges that health care professionals face in diagnosing zoonotic disease. This review describes the factors that influence diagnosis of these diseases, as well as potential methods that the Extension professional can use to convert those challenges into effective educational messages.

Genetic Parameters For Residual Feed Intake, Feed Efficiency And Average Daily Gain In Landrace Pigs, Thivakorn Sirichokchatchawan, Nalinee Imboonta

The Thai Journal of Veterinary Medicine

Residual feed intake (RFI) is the difference between the actual feed intake (AFI) and the expected feed intake (EFI). RFI has become an increasingly important trait and is being considered as a more practical approach to evaluate feed efficiency (FE) in livestock. Data from 479 purebred Landrace pigs involved in a performance test were used in this study. Pigs were housed in an individual pen and fed ad libitum the same formula diet consisting of 2,950 kcal/kg of ME and 16% crude protein. Clean water was available to the pigs at all time. Pigs were weighed at the beginning and …

Intervention Technique Using Transvenous Patent Ductus Arteriosus (Pda) Occluder In A Dog, Chollada Buranakarl, Anusak Kijtawornrat, Wasan Udayachalerm, Sirilak Disatian Surachetpong, Saikaew Sutayatram, Pasakorn Briksawan, Suwicha Chuthathep, Rampaipat Tungjitpeanpong, Nardtiwa Chaivoravitsakul

The Thai Journal of Veterinary Medicine

The first case interventional technique of Patent Ductus Arterious (PDA) correction was conducted in a 2 years old Golden Retriever. The dog was presented with continuous murmur with a marked left-side heart enlargement, insufficiency of pulmonic, mitral, and aortic valves. The definitive diagnosis for PDA was performed by echocardiography. The dog received PDA correction with interventional PDA occluding device consisting of nitinol wire mesh under fluoroscope at the Small Animal Teaching Hospital, Faculty of Veterinary Science, Chulalongkorn University with collaboration by medical expertise from Faculty of Medicine, Chulalongkorn University. The procedure was successful as measured by complete occlusion of PDA …

Molecular Detection Of Blood Protozoa In Ticks Collected From Cattle In The Buffer Zone Of Sai Yok National Park, Thailand, Satawat Poolkhetkit, Worrapon Chowattanapon, Sivapong Sungpradit, Tanasak Changbunjong

The Thai Journal of Veterinary Medicine

Ixodid ticks transmit many pathogens to both animals and humans. This study was carried out to detect tick-borne protozoa (Theileria and Babesia) in ticks collected from cattle in the buffer zone of Sai Yok National Park, Thailand. A total of 30 cattle were examined for tick infestation. Of these, 10 (33.3%) were infested with ticks. A total of 85 ticks were collected and identified as Rhipicephalus (Boophilus) microplus. The collected ticks were separated into 50 tick pools by sex and life stage. These pools were examined for Theileria and Babesia species by polymerase chain reaction (PCR) for amplification of a …

The Legacy Of Rudolph Ackermann And Nineteenth-Century British Literary Annuals, Katherine D. Harris

Faculty Research, Scholarly, and Creative Activity

By November 1822, the British reading public had already voraciously consumed both Walter Scott’s expensive novels and Rudolf Ackermann’s exquisite lithographs. The next decade, referred to by some scholars as dormant and unproductive, is in fact bursting with Forget Me Nots, , Keepsakes, and Literary Souvenirs. By wrapping literature, poetry, and art into an alluring package, editors and publishers saturated the market with a new, popular, and best-selling genre, the literary annual. In this excerpt from the introduction to Forget Me Not: The Rise of the British Literary Annual, the foundations of the literary annual, its …

The Psychological And Post-Colonial Approaches In Interpreting The Self And The Other In Heart Of Darkness And Things Fall Apart., Soumaya Ferchichi

Theses (Pre-2016)

To some critics, Things FallApart by Chinua Achebe, first published in 1958, comes to be the antithesis of Heart ofDarkness by Joseph Conrad, first published in 1899. In fact, this thesis will highlight Achebe's enthusiasm and nationalism that lead him to create a vivid picture of the African individual who is presented as belonging to a rich heritage of unique and complex African tradition. Achebe's characterization and representation of Africans in his novel is thought to be an ardent response to Conrad's assumed or perceived "racism." Yet, this thesis will discuss this dispute by giving new evidence to support Conrad's …

Detection Of Trace Metals (Ai, V, Cr, Mn, Co, Ni, Cu, U, Ba, Zn,As, Mo, Cd) In The Houston Ship Channel Water By Inductively Coupled Plasma Mass Spectroscopy (Icp-Ms), Boingoc Thi Dang

Theses (Pre-2016)

The Houston Ship Channel is one of the nation busiest seaports. The channel has been transporting goods to the sea since 1836. The oil and gas industry has started to emerge in Texas, leading to the building and construction of numerous refineries around the ship channel (Port of Houston, 2012). The basis of this research was to investigate the concentration of trace metals in the Ship Channel of Houston. Houston is known for its oil and gas refineries and also the heavy metals that might be discharged through waste associated with surrounding industries. The Ship Channel has a large amount …

Evaluation Of Equivalence Relations: Models Of Assessment And Best Practice, Dawn Amber Seefeldt

Dissertations

Due to changing age demographics in the United States, by 2050, an estimated 62.1 Americans will be over the age of 65 and the number of Americans with cognitive impairment, such as Alzheimer’s disease, will increase drastically as well (Alzheimer’s Association, 2014; Ortman, Velkoff, & Hogan, 2014). Once a diagnosis or behavioral indicators of cognitive impairment are present, it would be beneficial to apply a treatment package that promotes the maintenance or re-establishment of stimulus control in the environment. From a behavioral perspective, stimulus control aids in learning and memory through both respondent and operant conditioning. In the current study, …

A Quantified Approach To The Functional Longevity Of Geosynthetic Rolled Erosion Control Products (Grecps), Drew A. Loizeaux

Masters Theses and Doctoral Dissertations

Geosynthetic Rolled Erosion Control Products (GRECPs) have been utilized for decades in a multitude of applications to mitigate erosion resulting from land disturbance in civil construction projects. GRECPs vary from one type to another, ranging in performance and design life due to their composition and intended purpose. The coverage and durability of the GRECP are fundamental properties that can predict performance and fitness for use. Both coverage and durability will degrade over the design life of the GRECP to the point that fitness for use is unacceptable for the intended application. A standard approach is needed to quantify this material …

Problem Solving And Tool Use In Three Species Of Otter, Robert F. Gormley

Masters Theses and Doctoral Dissertations

Sea otters are well known tool users, yet the cognitive capacities of other otter species have been sparsely studied. Precedent exists for non-tool using species closely related to native tool users to display comparable abilities under experimental conditions. The social intelligence hypothesis predicts complex cognitive capacities in socially complex species. Using the Aesop’s Fable paradigm – wherein subjects drop stones into a cylinder half-filled with water to acquire floating out-of-reach food items – I assessed North American river otters’, Asian small-clawed otters, and giant river otters abilities to solve a novel tool-mediated problem. Sticks and water were presented with the …

The Color Of The Year: A Textual Analysis Of Pantone’S Color Communication Techniques Through The Application Of Barthes’ Semiotic, Kyung Lee

Masters Theses

This research analyzes the content of Pantone’s color of the year in 2000, 2002, 2009, 2014 and 2015 utilizing Barthes’ semiological system from a communication perspective. This study scrutinizes the announcement of Pantone’s color of the year as well as its color story to discover the purpose and the effectiveness of the verbalized nomination. The result reveals the significance of the semantic nature, which directs individuals’ viewpoint and creates a new connotation to alter their preconception. Also, Pantone’s color of 2014, Radiant Orchid, verified that the consolidation of the visual image and verbal content can maximize the influences that the …

Characterising Cytotoxicity And Genotoxicity Of Chemotherapeutic Agents (Etoposide And Vincristine) On Tk6, A Human Lymphoblastoid Cell Line, Leanne Edermaniger

The Plymouth Student Scientist

The ability of the chemotherapeutic agents namely etoposide and vincristine to cause cytotoxic and genotoxic damage to the human lymphoblastoid cell line, TK6, was at the centre of this study. Four different cytotoxic assays were tested for their ability to assess the cytotoxicity of the agents as well as two genotoxic assays to examine their ability to induce DNA damage. The TK6 cell line was exposed to increasing doses of the chemotherapeutic agents and cytoxicity assessed by in vitro trypan blue, neutral red uptake, LDH leakage and the glucose oxidase assays. The trypan blue assay was deemed to be the …

Exposure To Predator Kairomones Influences Egg Number And Size In Littorina Littorea, Jessica Raynor, Simon Rundle

The Plymouth Student Scientist

Predator kairomones play an important role in intertidal ecosystems, but knowledge on their potential role in influencing maternal effects is lacking. The aim of this study was to test whether egg production by female Littorina littorea was influenced by short-term exposure to predator kairomones before egg laying. Laboratory populations were exposed to predator cues from the intertidal crab Carcinus maenas for nine days, and egg number, egg size, and survivorship of the offspring were measured and compared with those from reference populations. Snails exposed to predator cues produced significantly more eggs, which were also significantly smaller than those produced from …

The Association Of Microstructural Connectivity In The Brain And Auditory Modulation Of Representational Momentum, Emma Theobald

The Plymouth Student Scientist

Perceived displacement from an object’s forward trajectory results in a representational momentum (RM) effect. In a behavioural task, participants watched a video of an actor reaching for/withdrawing from an object after hearing ‘I’ll take it’ or ‘I’ll leave it’, which was either congruent or incongruent with the subsequent action witnessed. The knowledge of other people’s intentions through auditory cues and then the predictions of their actions have been found to create an effect on the strength of RM experienced. The degree to which this auditory information affects the RM effect differs for each individual. This variation could, at least partially, …

Nanoparticle Conversion To Biofilms: In Vitro Demonstration Using Serum-Derived Mineralo-Organic Nanoparticles, Tsui-Yin Wong, Hsin-Hsin Peng, Cheng-Yeu Wu, Jan Martel, David M. Ojcius, Fu-Yung Hsu, John Ding-E. Young

All Dugoni School of Dentistry Faculty Articles

Aims: Mineralo-organic nanoparticles (NPs) detected in biological fluids have been described as precursors of physiological and pathological calcifications in the body. Our main objective was to examine the early stages of mineral NP formation in body fluids. Materials & methods: A nanomaterial approach based on atomic force microscopy, dynamic light scattering, electron microscopy and spectroscopy was used. Results: The mineral particles, which contain the serum proteins albumin and fetuin-A, initially precipitate in the form of round amorphous NPs that gradually grow in size, aggregate and coalesce to form crystalline mineral films similar to the structures observed in calcified human arteries. …

Effects Of A Software Program Vs. Constant Time Delay In The Acquisition Of Sight Words For A Student With Significant Disabilities, Turkie Ali Algharbie

Electronic Theses and Dissertations

The development of sight words is essential for individuals with significant disability. There is a plethora of research highlighting the acquisition of sight words for this population but to date, most focus on teacher led interventions (Browder, Algrim-Delzell, Spooner, Mims, & Baker, 2009). This study investigated the use of computer technology vs. one-on-one instruction targeting sight words acquisition for a student with a significant disability. Results showed the participant indicated improved performance using the computer based intervention versus the constant time delay instructor led intervention.

Modifying A Cow-Calf Biophysical Simulation Model For Analyses Of Alternative Enterprises, Jennifer L. Lutes

Graduate Theses and Dissertations

Cow-calf producers in the United States, tasked with providing beef calves for the beef industry, have had a multitude of difficulties to overcome in recent years. Producers in northwest Arkansas were negatively impacted by high hay prices coupled with low beef cattle market prices due to severe drought experienced in portions of 2010, 2011, and 2012. During this time they also faced high grain prices, due to a record low harvest, combined with portions of the corn harvest diverted from human and animal feed to ethanol production. Tight lending policies of this time, reminiscent of the housing market crash in …

Training Deictic Relations To Children With Developmental Delays Through The Use Of The Peak Relational Training System, Dena Larae Kime

Theses

Children with developmental delays often do not acquire perspective taking skills without training. These skills are imperative to the ability to relate to others socially and the development of appropriate social behavior. They may lack the ability to recognize that another person’s view may differ from their own, or that reality may differ from appearance. This study used deictic relational training to aid in the development of a ‘Theory of Mind’ and the acquisition of perspective taking skills. The PEAK relational training system was used in a special education classroom to train YOU and I relations, as well as YOU …

Sophorolipid Production From Lignocellulosic Biomass Feedstocks, Abdul Samad

Theses

The present study investigated the feasibility of production of sophorolipids (SLs) using yeast Candida bombicola grown on hydrolysates derived lignocellulosic feedstock either with or without supplementing oil as extra carbon source. Several researchers have reported using pure sugars and various oil sources for producing SLs which makes them expensive for scale-up and commercial production. In order to make the production process truly sustainable and renewable, we used feedstocks such as sweet sorghum bagasse, corn fiber and corn stover. Without oil supplementation, the cell densities at the end of day-8 was recorded as 9.2, 9.8 and 10.8 g/L for hydrolysate derived …

Improving Evaluation In Nonprofit Organizations: A Study Of How Evaluation Requests For Proposals Are Developed, Responded To, And Fulfilled, Nakia S. Matthews

Dissertations

It is often necessary for nonprofit organizations (NPOs) to formulate a Request for Proposal (RFP) to procure essential contracted services. This is most common when seeking the services of an external evaluator. Since most NPOs do not have internal evaluation staff, developing an appropriate RFP can be quite challenging. With limited literature and resources to guide NPOs on how to prepare RFPs, the process for procuring qualified evaluators can be even more daunting. This lack of resources and supports can lead to insufficient or incomplete RFPs, subsequently narrowing the pool of qualified potential bidders and reducing the extent to which …

Mountain Big Sagebrush (Artemisia Tridentata Ssp Vaseyana) Seed Production, Melissa L. Landeen

Theses and Dissertations

Big sagebrush (Artemisia tridentata Nutt.) is the most widespread and common shrub in the sagebrush biome of western North America. Of the three most common subspecies of big sagebrush (Artemisia tridentata), mountain big sagebrush (ssp. vaseyana; MBS) is the most resilient to disturbance, but still requires favorable climactic conditions and a viable post-fire seedbank for successful unassisted recovery. This study was designed to assess MBS seed production throughout post-fire recovery. We performed 2 pilot studies to develop methods for estimating seed production and plant age. The results of the pilot studies and a space-for-time substitution strategy were used to measure …

A Corpus-Based Analysis Of Russian Word Order Patterns, Stephanie Kay Billings

Theses and Dissertations

Some scholars say that Russian syntax has free word order. However, other researchers claim that the basic word order of Russian is Subject, Verb, Object (SVO). Some researchers also assert that the use of different word orders may be influenced by various factors, including positions of discourse topic and focus, and register (spoken, fiction, academic, non-academic). In addition, corpora have been shown to be useful tools in gathering empirical linguistic data, and modern advances in computing have made corpora freely available and their use widespread. The Russian National Corpus is a large corpus of Russian that is widely used and …