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2014

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P53 And Cancer-Associated Sialylated Glygans Are Surrogate Markers Of Cancerization Of The Bladder Associated With Schistosoma Haematobium Infection, Julio Santos, Elisabete Fernandes, Jose Alexandre Ferreira, Luis Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, Jose Manuel Correia Da Costa, Paul J. Brindley, Carlos Lopes, Lucio L. Santos Dec 2014

P53 And Cancer-Associated Sialylated Glygans Are Surrogate Markers Of Cancerization Of The Bladder Associated With Schistosoma Haematobium Infection, Julio Santos, Elisabete Fernandes, Jose Alexandre Ferreira, Luis Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, Jose Manuel Correia Da Costa, Paul J. Brindley, Carlos Lopes, Lucio L. Santos

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers.

Methodology/Principal Findings

Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder …


The Public Health Exposome: A Population-Based, Exposure Science Approach To Health Disparities Research, Paul D. Juarez, Patricia Matthews-Juarez, Darryl B. Hood, Wansoo Im, Robert S. Levine, Barbara J. Kilbourne, Michael A. Langston, Mohammad Z. Al-Hamdan, William L. Crosson, Maurice G. Estes, Sue M. Estes, Vincent K. Agboto, Paul Robinson, Sacoby Wilson, Maureen Y. Lichtveld Dec 2014

The Public Health Exposome: A Population-Based, Exposure Science Approach To Health Disparities Research, Paul D. Juarez, Patricia Matthews-Juarez, Darryl B. Hood, Wansoo Im, Robert S. Levine, Barbara J. Kilbourne, Michael A. Langston, Mohammad Z. Al-Hamdan, William L. Crosson, Maurice G. Estes, Sue M. Estes, Vincent K. Agboto, Paul Robinson, Sacoby Wilson, Maureen Y. Lichtveld

Sociology Faculty Research

The lack of progress in reducing health disparities suggests that new approaches are needed if we are to achieve meaningful, equitable, and lasting reductions. Current scientific paradigms do not adequately capture the complexity of the relationships between environment, personal health and population level disparities. The public health exposome is presented as a universal exposure tracking framework for integrating complex relationships between exogenous and endogenous exposures across the lifespan from conception to death. It uses a social-ecological framework that builds on the exposome paradigm for conceptualizing how exogenous exposures “get under the skin”. The public health exposome approach has led our …


The Principle Of Reciprocity In Hospitality Contexts: The Relationship Between Tipping Behavior And Food Servers’ Approaches To Handling Leftovers, John S. Seiter, Harry Weger Dec 2014

The Principle Of Reciprocity In Hospitality Contexts: The Relationship Between Tipping Behavior And Food Servers’ Approaches To Handling Leftovers, John S. Seiter, Harry Weger

Languages, Philosophy, and Communication Studies Faculty Publications

Based on the norm of reciprocity, this study hypothesized that food servers would earn higher tips when they boxed customers’ leftovers compared to having customers box leftovers themselves. In addition, the effect of writing messages (i.e., the date and/or customer’s name) on boxes of leftovers was explored. Two female food servers waited on 608 diners and boxed or did not box leftovers, and wrote or did not write messages on boxes. The hypothesis was supported. However, writing messages was not associated with tipping behavior.


December 11, 2014: No Justification For Torture, Bruce Ledewitz Dec 2014

December 11, 2014: No Justification For Torture, Bruce Ledewitz

Hallowed Secularism

Blog post, “No Justification for Torture“ discusses politics, theology and the law in relation to religion and public life in the democratic United States of America.


Examination Of Capital Murder Jurors’ Deliberations: Methods And Issues, Keith Price, Susan Coleman, Gary R. Byrd Dec 2014

Examination Of Capital Murder Jurors’ Deliberations: Methods And Issues, Keith Price, Susan Coleman, Gary R. Byrd

Administrative Issues Journal

The study of capital juries remains a subject of critical interest for the public and for legislative and judicial policy makers as well as legal scholars and social scientists. Cowan, Thompson, and Ellsworth established one of the standard methodologies for examination of this topic in their 1984 seminal study by observing the subjects’ debate about conviction in a death penalty case utilizing mock juries; other scholars employed different techniques to add more information in the late 1990s. Yet, the question of death qualification and prosecutorial bias remains open to inquiry. This preliminary study found evidence to support bias toward conviction …


Wagner V. State Appellant's Reply Brief Dckt. 41677 Dec 2014

Wagner V. State Appellant's Reply Brief Dckt. 41677

Idaho Supreme Court Records & Briefs, All

No abstract provided.


Regulation Of Three Nitrogenase Gene Clusters In The Cyanobacterium Anabaena Variabilis Atcc 29413, Teresa Thiel, Brenda Pratte Dec 2014

Regulation Of Three Nitrogenase Gene Clusters In The Cyanobacterium Anabaena Variabilis Atcc 29413, Teresa Thiel, Brenda Pratte

Biology Department Faculty Works

The filamentous cyanobacterium Anabaena variabilis ATCC 29413 fixes nitrogen under aerobic conditions in specialized cells called heterocysts that form in response to an environmental deficiency in combined nitrogen. Nitrogen fixation is mediated by the enzyme nitrogenase, which is very sensitive to oxygen. Heterocysts are microxic cells that allow nitrogenase to function in a filament comprised primarily of vegetative cells that produce oxygen by photosynthesis. A. variabilis is unique among well-characterized cyanobacteria in that it has three nitrogenase gene clusters that encode different nitrogenases, which function under different environmental conditions. The nif1 genes encode a Mo-nitrogenase that functions only in heterocysts, …


Exploring The Intersection Between Folk And Conventional Medicine In Albany, Kentucky, Chloe J. Brown Dec 2014

Exploring The Intersection Between Folk And Conventional Medicine In Albany, Kentucky, Chloe J. Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Approximately 60% of patients surveyed (in Albany, KY) practice folk medicine, which suggests that a significant segment of the population may practice folk medicine. Patients typically use folk medical treatments concurrently with conventional medical treatments; while the interaction of these treatments is generally innocuous or positive, folk medical treatments can sometimes be harmful, lead to negative interactions with other drugs prescribed by a conventional medical professional. Since folk medicine and conventional medicine frequently interact, it is important for medical professionals to be aware of and address folk medical practices in a conventional medical environment. In order to better address folk …


Academic Standards Subcommittee Agenda, December 11, 2014, Utah State University Dec 2014

Academic Standards Subcommittee Agenda, December 11, 2014, Utah State University

Educational Policies Committee

  • International Baccalaureate Organization (IBO) Awarding of Credit Policy
  • Excused Absence Policy


Ifn-Γ Causes Aplastic Anemia By Altering Hematopoietic Stem/Progenitor Cell Composition And Disrupting Lineage Differentiation, Fan Ching Lin, Megan Karwan, Bahara Saleh, Deborah L. Hodge, Tim Chan, Kimberly C. Boelte, Jonathan R. Keller, Howard A. Young Dec 2014

Ifn-Γ Causes Aplastic Anemia By Altering Hematopoietic Stem/Progenitor Cell Composition And Disrupting Lineage Differentiation, Fan Ching Lin, Megan Karwan, Bahara Saleh, Deborah L. Hodge, Tim Chan, Kimberly C. Boelte, Jonathan R. Keller, Howard A. Young

United States Public Health Resources

Aplastic anemia (AA) is characterized by hypocellular marrow and peripheral pancytopenia. Because interferon gamma (IFN-γ) can be detected in peripheral blood mononuclear cells of AA patients, it has been hypothesized that autoreactive T lymphocytes may be involved in destroying the hematopoietic stem cells. We have observed AA-like symptoms in our IFN-γ adenylate-uridylate-rich element (ARE)-deleted (del) mice, which constitutively express a low level of IFN-γ under normal physiologic conditions. Because no T-cell autoimmunity was observed, we hypothesized that IFN-γ may be directly involved in the pathophysiology of AA. In these mice, we did not detect infiltration of T cells in bone …


The Role Of Violence Within And Across Self-Identified Gang Youth, J. Michael Vecchio Dec 2014

The Role Of Violence Within And Across Self-Identified Gang Youth, J. Michael Vecchio

Dissertations

Whether actual (i.e., direct and vicarious victimization) or anticipated (i.e., fear of crime and perceived risk of victimization) violence, gang youth commonly discuss violence in terms of having an important role in both their gang experiences and daily lives. In particular, violence can play an important role within the specific stages of the gang experience – 1) joining, 2) active membership, and 3) leaving. This includes the importance of protection from violence as a common motivator for joining, the utility of violence as a means of building cohesion between active gang members, as well as the importance of exposure to …


Usa V. Devin Terry Dec 2014

Usa V. Devin Terry

2014 Decisions

USDC for the Eastern District of Pennsylvania


John Gehringer V. Atlantic Detroit Diesel Alliso Dec 2014

John Gehringer V. Atlantic Detroit Diesel Alliso

2014 Decisions

USDC for the District of New Jersey


Joyce Royster V. Laurel Highlands School Distri Dec 2014

Joyce Royster V. Laurel Highlands School Distri

2014 Decisions

USDC for the Western District of Pennsylvania


In Re: Dwight Bell Dec 2014

In Re: Dwight Bell

2014 Decisions

USDC for the District of New Jersey


In Re: Gerald Bush Dec 2014

In Re: Gerald Bush

2014 Decisions

USDC for the Eastern District of Pennsylvania


In Re: Diet Drugs Dec 2014

In Re: Diet Drugs

2014 Decisions

USDC for the Eastern District of Pennsylvania


Usa V. James King Dec 2014

Usa V. James King

2014 Decisions

USDC for the Middle District of Pennsylvania


American Capital Acquisitions V. Fortigent Llc Dec 2014

American Capital Acquisitions V. Fortigent Llc

2014 Decisions

USDC for the District of New Jersey


Edward Miller, Jr. V. Commonwealth Of Pennsylvania Dec 2014

Edward Miller, Jr. V. Commonwealth Of Pennsylvania

2014 Decisions

USDC for the Eastern District of Pennsylvania


Yakov Drabovskiy V. Warden Allenwood Fci Dec 2014

Yakov Drabovskiy V. Warden Allenwood Fci

2014 Decisions

USDC for the Middle District of Pennsylvania


In Re: Kirk Stephan Dec 2014

In Re: Kirk Stephan

2014 Decisions

USDC for the District of New Jersey


Julius Lockhart V. City Of Easton Dec 2014

Julius Lockhart V. City Of Easton

2014 Decisions

USDC for the Eastern District of Pennsylvania


Usa V. Christian Kowalko Dec 2014

Usa V. Christian Kowalko

2014 Decisions

USDC for the Eastern District of Pennsylvania


Fsec Meeting Minutes December 11, 2014, University Of Rhode Island Faculty Senate Dec 2014

Fsec Meeting Minutes December 11, 2014, University Of Rhode Island Faculty Senate

Faculty Senate Executive Committee Minutes

No abstract provided.


Autonomous Vehicle Law Report And Recommendations To The Ulc Based On Existing State Av Laws, The Ulc's Final Report, And Our Own Conclusions About What Constitutes A Complete Law, University Of Washington Technology Law And Public Policy Clinic Dec 2014

Autonomous Vehicle Law Report And Recommendations To The Ulc Based On Existing State Av Laws, The Ulc's Final Report, And Our Own Conclusions About What Constitutes A Complete Law, University Of Washington Technology Law And Public Policy Clinic

Technology Law and Public Policy Clinic

This report was created by the University of Washington’s Technology Law and Policy Clinic for the Uniform Law Commission (ULC). It was created at the request of Robert Lloyd, Professor of Law at the University of Tennessee and a member of the ULC’s subcommittee for autonomous vehicles. The report aims to do three things: (1) present the existing autonomous vehicle provisions on the books in California, Michigan, Florida, Nevada, and Washington, D.C.; (2) analyze these provisions, address related questions raised in the ULC’s Final Report, and make recommendations to the ULC; and (3) offer draft provision language to illustrate our …


Moral Anxiety, Mortal Terror: Considering Spielberg, Post-9/11, Jake T. Bart Dec 2014

Moral Anxiety, Mortal Terror: Considering Spielberg, Post-9/11, Jake T. Bart

Cinesthesia

In the wake of 9/11, a defining moment in the young 21st century, Spielberg’s thematic concerns undergo a marked evolution. As film historian Joseph McBride noted, “(n)o other American artist confronted the key events of the first decade of the century with such sustained and ambitious treatment” (450). Together, Spielberg’s War of the Worlds (2005), Munich (2005), and Minority Report (2002) create an informal trilogy, each exploring a different facet of American shock and anxiety in the War on Terror era.


Daily Eastern News: December 11, 2014, Eastern Illinois University Dec 2014

Daily Eastern News: December 11, 2014, Eastern Illinois University

December

No abstract provided.


Mono- And Digalactosyldiacylglycerol Lipids Function Nonredundantly To Regulate Systemic Acquired Resistance In Plants, Qing-Ming Gao, Keshun Yu, Ye Xia, M. B. Shine, Caixia Wang, Duroy Navarre, Aardra Kachroo, Pradeep Kachroo Dec 2014

Mono- And Digalactosyldiacylglycerol Lipids Function Nonredundantly To Regulate Systemic Acquired Resistance In Plants, Qing-Ming Gao, Keshun Yu, Ye Xia, M. B. Shine, Caixia Wang, Duroy Navarre, Aardra Kachroo, Pradeep Kachroo

Plant Pathology Faculty Publications

The plant galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO). Here, we show that DGDG contributes to plant NO as well as salicylic acid biosynthesis and is required for the induction of systemic acquired resistance (SAR). In contrast, MGDG regulates the biosynthesis of the SAR signals azelaic acid (AzA) and glycerol-3-phosphate (G3P) that function downstream of NO. Interestingly, DGDG is also required for AzA-induced SAR, but MGDG is not. Notably, …


A Critical Analysis Of Infant Mortality In Kalamazoo County, Audrey Jensen Dec 2014

A Critical Analysis Of Infant Mortality In Kalamazoo County, Audrey Jensen

Honors Theses

The following is a review of the state of infant and fetal health in Kalamazoo County in the 21st century. Since infant health is a marker for the effectiveness of health care, this review will analyze the leading causes of infant mortality in Kalamazoo County. Statistical indicators show that Kalamazoo County falls below both state and national IMR averages. The leading causes of infant mortality in Kalamazoo are considered preventable infant deaths. Therefore, this review will make recommendations for the reduction of IMR through the improvement of preventative prenatal healthcare practices.