Digital Commons Network^™

National Child Maltreatment Response And Foster Care Entries: 2005-2010, Zeinab Chahine

Dissertations, Theses, and Capstone Projects

This study involves secondary analysis of the national administrative data contained in two major federal child maltreatment and foster care data systems, the National Child Abuse and Neglect Data System and the Adoption and Foster Care Analysis and Reporting System for 2005 to 2010. The study examines the data related to screening in and determination of maltreatment reports (child maltreatment response), as well as the provision of services to children referred for maltreatment. The purpose is to determine how the child welfare services/child protective services systems responses to child maltreatment contributed to the 17% decline in foster care entries from …

Roles Of Dopamine D1 And D2, Opioid And Glutamate Nmda Receptor Signaling In The Acquisition And Expression Of Fat- And Glucose-Conditioned Flavor Preferences In Rats And C-Fos Analysis Of The Dopamine Mesotelencephalic And Nigrostriatal Pathways Following Intake Of Sugars And Fats In Rats, Julie Dela Cruz

Dissertations, Theses, and Capstone Projects

Systemic administration of the non-competitive NMDA antagonist, MK-801, demonstrated that acquisition, but not expression, were found to affect the orosensory-mediated (flavor/flavor: f/f) fructose-conditioned flavor preference (CFP). The present studies demonstrated a similar outcome when f/f and f/n processes were combined. Fat-CFP and glucose-CFP studies indicated that systemic injections of the NMDA antagonist, MK-801, were able to significantly reduce acquisition, but not expression, of Corn-Oil (CO)-CFP and glucose-CFP. Both studies appear to have mitigated effects on acquisition as compared to the separate orosensory and postingestive CFP studies.

Previous studies found that systemic administration of dopamine (DA) D1 (SCH23390) and D2 (raclopride) …

Mechanisms Of Regulation Of Mrna 3' Processing By P53 Pathway, Emral Cakmak Devany

Dissertations, Theses, and Capstone Projects

Although the p53 network has been intensively studied, genetic analyses long hinted at the existence of components that remained elusive. This dissertation focuses on the study of the regulation of mRNA 3' processing during DNA damage response (DDR) by the p53 pathway and the regulation of p53 expression by the mRNA 3' processing machinery. The results in this dissertation revealed new roles of tumor suppressor p53 in mRNA 3' processing. In Chapter II, I showed that p53 inhibits the cleavage step of polyadenylation reaction and that cells with different levels of p53 expression have different mRNA processing profiles. As part …

Moral Motivation And The Authority Of Morality: A Defense Of Naturalist Moral Realism, Lily Eva Frank

Dissertations, Theses, and Capstone Projects

Moral realism has been continuously accused of positing the existence of queer properties, facts, judgments, and beliefs. One of these queer features is supposed to be the normative force of morality-that is the way in which morality guides our actions. Critics of moral realism argue that nothing else in the world has this feature. This is a reason to doubt that moral facts and properties exist at all. This objection can be interpreted in at least two ways. One way to interpret it has to do with moral motivation, this is the internalism objection. The other has to do with …

Cisgenderism In Gender Attributions: The Ways In Which Social, Cognitive, And Individual Factors Predict Misgendering, Erica Jayne Friedman

Dissertations, Theses, and Capstone Projects

The current program of research investigated the ways in which social representations of gender, cognitive processes, and individual factors can be integrated to predict "misgendering," an example of cisgenderism in which people are categorized as a gender with which they do not identify. I proposed an (In)consistency Processing Model of Gender Attribution in which perceivers make a gender attribution by interpreting the stereotype-(in)consistencies of a target's gender characteristics through either a biology- or identity-based schema. Five studies were conducted to test different aspects of this model, the first of which was a secondary data analysis on a sample of students …

Run For Health: Health(Icization), Supplements, And Doping In Non-Elite Road Running, April D. Henning

Dissertations, Theses, and Capstone Projects

Running races are commonly viewed as one of the clearest examples of competition and it is less common to view training or racing as a non-competitive health practice. However, the majority of non-elite runners who participate in races do so in order to reap benefits from the training process many undertake in preparation for a race. This dissertation is a study of non-elite or amateur runners' pursuit of health, their varied understandings of health, the ironies and inconsistencies of healthism, and the folk measures of health employed within the running community. Through qualitative interviews with amateur runners in New York …

From Berlin To Broadacres: Central European Influence On American Visionary Urbanism, 1910-1935, Margaret Herman

Dissertations, Theses, and Capstone Projects

In the 1920s and 1930s, Eliel Saarinen, Richard Neutra, and Frank Lloyd Wright each designed plans for real and imagined American cities. Saarinen's Chicago and Detroit plans of 1923-1924, Neutra's Rush City Reformed of 1926, and Wright's Broadacre City of 1935 are stylistically unique but all contain a similar fascination with hypothetical transportation networks and high-speed expansion that reflect a common relationship to the development of urban planning as a discrete field in Berlin and Vienna around 1910.

This dissertation will highlight several features of turn-of-the-century Central European planning that played an outsize role in the development of these visionary …

Assembling Autism, Kate Suzanne Jenkins

Dissertations, Theses, and Capstone Projects

Autism is a growing social concern because of the epidemic-like growth in diagnoses among children. The lives and experiences of adults who have an autism diagnosis, however, are not as well documented. This dissertation project seeks to resolve that dearth of research. I conducted a year of participant observation at four locations of social, self-advocacy, and peer to peer support groups. I also conducted interviews with leaders and participants. I also participated (as a researcher) in an experiment in social skills acquisition led by participants from my ethnographic field work, fulfilling the planned participatory action research component of my original …

Successful Aging: Use Of Communication Technology In An Adult Day Program, Wendy Johnson

Dissertations, Theses, and Capstone Projects

This dissertation investigated the relationship between learning digital communication technologies in an intergenerational intervention and successful aging among older adults. The specific goal of this study was to uncover the effects of this intervention on the cultural constructions of aging in an urban Adult Day Program in Trinidad and Tobago. This mixed method study utilized the Geriatric Depression Scale (GDS; Sheikh & Yesavage, 1986), a life satisfaction scale, well-being measurements, open-ended survey questionnaires and a focus group session. The results from the quantitative items indicated no significant differences after the intervention; however, the focus group discussion and open-ended surveys provided …

Phylogeography Of E1b1b1b-M81 Haplogroup And Analysis Of Its Subclades In Morocco, Ahmed Reguig, Nourdin Harich, Abdelhamid Barakat, Hassan Rouba

Human Biology Open Access Pre-Prints

In this work, we have analyzed a total of 295 unrelated Berber-speaking men from the northern, center and southern of Morocco, in order to characterize frequency of E1b1b1b-M81 haplogroup and to refine the phylogeny of its subclades: E1b1b1b1-M107, E1b1b1b2-M183 and E1b1b1b2a-M165. For this purpose, we have typed four biallelic polymorphisms: M81, M107, M183 and M165. As results, a large majority of the Berber-speaking male lineages belong to the Y chromosomal E1b1b1b-M81 haplogroup. The frequency ranged from 79.1 to 98.5% in all localities sampled. Then, the E1b1b1b2-M183 was the most dominant subclade in our samples, which ranged from 65.1% to 83.1%. …

Creating And Using Interactive Presentations In Distance Education Courses: A View From The Instructor's Chair, Karen K. Hein

Department of Teaching, Learning, and Teacher Education: Theses and Other Student Research

Instructors of distance education courses have many choices when it comes to designing course materials and learning experiences. One approach has been to develop interactive presentations – audio voice-over slide presentations or presentations incorporating voice-over narration plus other interactive elements. Some of the previous research has focused upon the impact of these types of instructional materials on student academic achievement (Stephenson, Brown, Griffin, 2008; Lents & Cifuentes, 2009; Savoy, Proctor, & Salvendy, 2009; and Geri, 2011). Others have examined interactive presentations from a limited instructor perspective, focusing on the tools and preferences in specific disciplines (Pace & Kelly, 2006; Burke, …

Examining The Association Of Medication Complexity With Health-Related Quality Of Life In Older Adults Receiving Community-Based Long Term Services And Supports, Claudia Ann Beck

Dissertations, Theses, and Capstone Projects

While the complexity of a medication regimen is a concern for all individuals, it is of significant concern for community-dwelling older adults who often require multiple medications to treat chronic health problems. Health related quality of life (HRQoL) has been identified as a key quality outcome measure when assessing care of older adults, particularly those with long-term care needs. Although the use of multiple medications has been widely explored in the literature, there is a paucity of data regarding the combination of several medication-related factors (number of active medications, therapeutic drug class, and medication regimen complexity) and HRQoL in older …

Women In Foreclosure: Social Reproduction & Mortgage Strain In The Subprime Era, Amy Baker

Dissertations, Theses, and Capstone Projects

Advisor: Professor Mimi Abramovitz

This research captures the experiences of 31 single female homeowners with risky lending markets and mortgage foreclosure in the city of Philadelphia. In-depth, semi-structured interviewing was employed to build knowledge about single women's experiences with seeking a loan, buying a home, entering default and attempting to stall foreclosure. Thematic analysis of the data demonstrated that risky lending and foreclosure did not mark the onset of financial instability among study participants. Instead, it functioned as a tipping point for single women unable to access upward mobility and asset accrual throughout the lifespan. Women's status as the strongest …

Cologne Carnival's "Alternative" Stunksitzung: Carnivalization? Meta-Carnival? Or Bakhtinian Restoration?, Erik Abbott

Dissertations, Theses, and Capstone Projects

In the 1820s, Carnival in Cologne, Germany, underwent a series of reforms, ostensibly to bring the festival back to the people. Among the traditions that developed was the Sitzung, a theatrical variety-show event, with music, comic speeches and sketches, dance troupes, and various additional Carnival-related entertainments. The shows, and Carnival itself were, and largely have been since that time, mostly overseen by a Festival Committee and the official Carnival Societies it recognizes.

In 1984, a group of mostly students decided to create their own version of a Sitzung, an alternative version, the Stunksitzung. From three inaugural performances, it has grown …

Structure And Function In Bacteriophage Phi6, James Carpino

Dissertations, Theses, and Capstone Projects

The present study of bacteriophage Phi6 has been preceded by a great number of exploratory studies of its structure and function, and these studies have formed a basis for Phi6's development into a model organism. In this study, two aspects of the model organism have been examined. 1. There are several uncharacterized and presumed untranslated regions (UTRs) in Phi6's 13.3 kilobase-pair dsRNA genome. I examined the impact of specific modification to the 3' UTR of the small segment of bacteriophage Phi6. I determined that modification to the purported UTR of the small segment resulted in severe fitness costs, supporting a …

Recruitment Of The Ribosomal 40s Subunit To The 3'Untranslated Region Of A Viral Mrna, Via The Eif4 Complex, Facilitates Cap-Independent Translation, Sohani Das Sharma

Dissertations, Theses, and Capstone Projects

Translation of uncapped plant viral RNAs can be facilitated by either an internal ribosomal entry site (IRES) in the 5' untranslated region (UTR) or a cap-independent translation element (CITE) in the 3' UTR. Barley yellow dwarf virus (BYDV) mRNA, which lacks both cap and poly(A) tail, has a translation element (3'BTE) in its 3' UTR that is essential for efficient translation initiation at the 5'-proximal AUG. This mechanism requires binding of the eukaryotic initiation factor 4G (eIF4G) subunit of the heterodimer eIF4F to the 3'BTE and base pairing between the 3'BTE and the 5' UTR. Here we investigate how this …

Comparative Phylogeography, Phylogenetics, And Population Genomics Of East African Montane Small Mammals, Terrence Constant Demos

Dissertations, Theses, and Capstone Projects

The Eastern Afromontane region of Africa is characterized by striking levels of endemism and species richness which rank it as a global biodiversity hotspot for diverse plants and animals including mammals, but has been poorly sampled and little studied to date. Using mtDNA and multi-locus nDNA sequence data, genome-wide RAD-Seq SNP data, and morphological data, I identify major cryptic biogeographic patterns within and between 11 co-distributed small mammal species/species groups across the Eastern Afromontane region. I focus on two endemic montane small mammal species complexes, Hylomyscus mice and Sylvisorex shrews, co-distributed across the Albertine Rift (AR) and Kenya Highlands (KH) …

Multimodal Emotion Perception In Borderline Personality Disorder, Virginia Fineran

Dissertations, Theses, and Capstone Projects

Borderline personality disorder (BPD) is a chronic disorder characterized by pervasive difficulties in the emotion regulation system. While it is clear that individuals with BPD frequently exhibit intense emotional reactions, lack abilities to effectively manage such emotions, and often engage in serious maladaptive behaviors as a consequence of intense emotions, many aspects of the process by which this sequence occurs are not well understood. One crucial aspect of emotion regulation is the processing and perception of cues from the environment. To date, processing of emotional cues in individuals with BPD has been understudied. Therefore, the purpose of this paper is …

Role Of The Polyadenylation Factor Cstf-50 In Regulating The Brca1/Bard1 E3 Ubiquitin (Ub) Ligase Activity, Danae Fonseca

Dissertations, Theses, and Capstone Projects

The cellular response to DNA damage is an intricate mechanism that involves the interplay among several pathways. The studies presented in this dissertation focus on the determination and characterization of the role of mRNA processing factor CstF-50 and escort protein p97 in the regulation of the BRCA1/BARD1 E3 ubiquitin (Ub) ligase activity during the DNA damage response (DDR).

As part of the studies presented in Chapter II, I determined that the polyadenylation factor CstF plays a direct role in DDR, specifically in transcription-coupled repair (TCR), and that it localizes with RNA polymerase II (RNAP II) and BARD1 to sites of …

Internalizing Disorders In Early Childhood: Professional Development Framework For Teachers, Danielle Guttman

Dissertations, Theses, and Capstone Projects

Recent research indicates that internalizing disorders such as depression, anxiety, and posttraumatic stress disorder (PTSD) manifest in young children. Since early childhood teachers spend a substantial portion of their day with young children, it is important to examine their beliefs and behaviors surrounding these disorders. The role of the school psychologist has come to include providing support for educators such as presenting up-to-date research through professional development (PD). The current investigation implemented an intervention designed to compare different forms of PD seminars ("Information" and "Strategies") designed to increase teachers' awareness of internalizing disorders in early childhood. Ninety-nine participants comprised the …

I Didn't Consent To That: Secondary Analysis Of Discrimination Against Bdsm Identified Individuals, Larry Iannotti

Dissertations, Theses, and Capstone Projects

Sadomasochism (BDSM) sexual behavior is an understudied phenomenon within the social sciences generally, and social work in particular. While BESM sexuality encompasses a wide variety of activities a community of individuals interested in BDSM is identifiable and has coalesced around organized groups, events, political activism, and shared sexual interests. This community has experienced discrimination, violence, and harassment (DVH) as a result of social approbation and stigma associated with BDSM practices. The study examines results of a secondary analysis of data from the Survey of Violence & Discrimination against Sexual Minorities, conducted in 2008. Severity and frequency of various types …

The Revolving Door Pattern Of Jail Incarceration And Homelessness And Its Influence On Mortality And Morbidity Among New York City Adults, Sungwoo Lim

Dissertations, Theses, and Capstone Projects

Objectives

The purpose of this dissertation study was to identify timing and sequencing of jail incarceration and homelessness by utilizing sequence analysis and to test whether a particular trajectory contributes to mortality risk and discontinuity of HIV care.

Methods

The main data source was an existing matched dataset, constructed using administrative data from the New York City (NYC) Departments of Health and Mental Hygiene, Correction, and Homeless Services. The study cohort consisted of 15,620 NYC adults with recent histories of both jail incarceration and homelessness. Monthly experiences of jail incarceration, homelessness, and community-dwelling in 2001-03 were summarized into trajectory groups …

Aging Out Of The Spectrum Of Cultural Visibility, Darthea M. Miller

Dissertations, Theses, and Capstone Projects

I argue that the valorization of youth and the subsequent quest for agelessness has caused such an explosion of ageism that the elderly have been relegated to a culturally invisible status. The intersection of age and gender is doubly problematic for women due to sexism and the perennial objectification of the female body. Thinking of visibility as a measure of social acceptability, the consequences of cultural disappearance for the aging woman is an important site for investigation and theorizing. This thesis depicts the erasure of aging women from the cultural landscape as an effect of media representation and self-care work …

Blogging Through Motherhood: Free Labor, Femininity, And The (Re)Production Of Maternity, Kara Mary Van Cleaf

Dissertations, Theses, and Capstone Projects

Drawing from a thematic analysis of 47 North American mommy blogs over a 2-year period, I situate the genre in critical discussions of feminism, media, and labor, exploring both the technological and cultural shifts that turn mothers into cultural producers and that turn the experience of motherhood into a commodity. I situate the content of such blogs, or what gets said therein, within theories of media, gender, and labor. Examining the blogs within and against such academic discussions allows me to develop an intersectional analysis of feminism, media, and labor studies.

Guatemalan Spanish As Act Of Identity: An Analysis Of Language And Minor Literature Within Modern Maya Literary Production, Kenneth Yanes

Dissertations, Theses, and Capstone Projects

My study approaches the use of Guatemalan Spanish in modern Maya literary works through a theoretical framework drawn on theories of "purity" and mestizaje, the concept of minor literature, and "image" and ideology of language. I problematize the "major"/"minor" dichotomy of language based on a Eurocentric view of the dominance of national languages as the extremely diverse linguistic ecology of Latin American lends itself to the deterritorialization of hegemonic discourse, but without sustaining a neat categorization of language. Guatemalan Spanish is a heavily Maya-inflected interlanguage share by all Guatemalans. Mayan writers chose purposefully to counter the ladino ethnocentrism of the …

Corticospinal Integration In Healthy Humans, Amanda Asmar, Leandra Manfredini, Kerri Mclean, Christina Scannapieco

Dissertations, Theses, and Capstone Projects

Synchronized arrival of neuronal signals from the periphery and motor cortex has been associated with neuronal plasticity and motor learning. The main objective of this study was to examine neuronal interactions following excitation of descending motor axons from the primary motor cortex (M1) and spinal neuronal circuits via transcranial magnetic stimulation (TMS) and transcutaneous electric stimulation of the spine (tsESS) in 15 healthy humans while seated semiprone. TMS was delivered below or above the resting motor evoked potential (MEP) threshold, for the tibialis anterior (TA) muscle, while tsESS was delivered at the lowest stimulation intensity that evoked responses in most …

The Effect Of Tdcs On Cd-1 Mouse Behavior Post Induced Sensorimotor Cortex Injury, Michelle Gardella, Natalia Gozias, Kristina Laktionova, Tricia Roehrig

Dissertations, Theses, and Capstone Projects

The functional topography of the motor cortex has been shown to be modifiable by transcranial direct current stimulation (tDCS). tDCS works by directing electrical currents into the brain which induces alterations in neuroplastic cortical excitability. This experiment’s aim was to test the effect of tDCS on recovery of skilled locomotion, recovery of balance, and recovery of grip strength after bilateral electrolytic lesions to sensorimotor cortices in mice. Tests employed in this experiment included the ladder test, grip test, and a balance pole test. We were able to show that 4 days of tDCS post brain injury in mice produced improvements …

Motor Imagery And Action Observation As An Alternative Gait Training Intervention For The Elderly, Matthew F. Cirelli, Brian Fettner, Lindita Ismaili, Danielle Jordan

Dissertations, Theses, and Capstone Projects

Motor imagery (MI) is the mental representation of movement without any body movement. Action observation (AO) is a non-physical method of training, in which the learner observes the action of another individual. Eighteen subjects between ages 60-80 were randomly assigned to 3 training groups, the MI, AO and motor training groups. All subjects were assessed and measured with the Expanded Timed-Get Up and Go (TUG) test and Figure-8-Walk (F8W) test. All three groups yielded a significant improvement in difference in total TUG time (<0.05). When individual aspects of the TUG were considered, the sit to stand component improved in the MI and Motor groups. The results of this study suggest that MI and AO can improve cadence and have an effect mirroring that of motor practice. If utilized properly, MI and AO may be indicated as a rehabilitation intervention adjunct to gait training, and potentially decrease the risk of falls in the elderly population.

A Review Of Animal Studies For The Efficacy Of D-Methionine In Reducing Threshold Shifts And Affecting Biochemical Changes After Exposure To Noise, Alexandra Petraru

Dissertations, Theses, and Capstone Projects

Noise induced hearing loss (NIHL) is a major public health concern in the United States and worldwide. Certain individuals such as factory workers and military personnel are at greatest risk for irreversible sensorineural hearing loss due to the limitations of hearing protection measures and devices. D-Methionine (d-Met) is an antioxidant otoprotective agent that currently is in human clinical trials. The purpose of this systematic literature review was to review d-Met’s efficacy in reducing threshold shifts as well as in producing biochemical and physical changes in animal studies vis-à-vis the administration paradigm (preloading, rescue and a combined approach), d-Met dose quantity …

The Effects Of Morning Versus Evening Stretching Exercises In Hamstrings Flexibility Gains, Camron Einerman, Emily Eleff, Ana Ilijeska, Aliza Zinberg

Dissertations, Theses, and Capstone Projects

Many human physiological functions, including muscle flexibility, exhibit a pattern over a 24-hour period, known as circadian rhythm. Muscle flexibility and its circadian rhythm have been researched, though much more information is needed, especially regarding the hamstring muscle group. The object of this study was to determine if stretching at different times of the day results in differences in hamstring flexibility. Since muscles and joints are most flexible at night, greater ranges of motion should be available, allowing for a greater degree of stretching to take place. We hypothesize that when utilizing the optimal type, duration, and frequency of stretch, …