Digital Commons Network^™

The Guardian, September 22, 2014, Wright State University Student Body

The Guardian Student Newspaper

Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

The Free Press Vol 46 Issue 3, 09-22-2014, Sam Hill

Free Press, The

Faculty admits no plan to teach out programs--Student Senate fights dwindling attendance--USM police department has four M16 rifles--Shark fishing trip consumed senate meeting--The Cost of Convenience: food prices compared--USM needs a new BoT representative

Dance For Your Life! : Tangoflow!® Technique And Implications In The Treatment Of Trauma : A Mixed-Methods Empirical Study, Catherine A. Salmons

Theses, Dissertations, and Projects

This thesis is a mixed-method, empirical study exploring the possible efficacy of TangoFlow!®—an original dance-conditioning technique based in Argentine tango, which I developed and trademarked in 2010—in reducing symptoms of trauma. Research employed both quantitative and qualitative measures to determine whether or not an eight-week intervention had any effect on type and severity of symptoms, as reported by participants. The sample (N=13) consisted of volunteer participants who self-identified as having a history of trauma. No specific information about their trauma history was solicited; rather, trauma symptoms were assessed through a pre-interview using a published testing instrument, the Trauma Symptom Inventory-2™, …

School Reform In Canada And Florida: A Study Of Contrast, Catherine S. Boehme

New England Journal of Public Policy

Alberta and Florida have instituted school reform initiatives over the past fifteen years in an effort to improve the quality of their schools. Alberta has focused on systemic improvement by engaging the community in educational needs assessment, raising the high standards of teacher preparation, and improving effective instructional practices through professional development. Florida’s efforts have concentrated on holding students, teachers, schools, and districts accountable for high-stakes testing results by increasing the number and rigor of required assessments and increasing the negative consequences for low achievement scores. The 2012 PISA scores reveal that Alberta’s students are maintaining their high rankings relative …

Editor's Note, Padraig O'Malley

New England Journal of Public Policy

On December 3, 2013, when the Organisation for Economic Co-operation and Development (OECD) released its Programme for International Student Assessment (PISA) scores, the ranking of the United States as number 27 on the global scoreboard elicited little surprise among teachers, educational professionals, academics, and educational policymakers. The usual platitudes were trotted out—no mention that the United States’ standing was getting any worse, just which other countries were passing us by. We were stuck at a perennial average.

The results are in a sense a metaphor of the slow decline of the United State since the 1970s from a position of …

“Me & My Brain”: Exposing NeuroscienceʼS Closet Dualism, Liad Mudrik, Uri Maoz

Psychology Faculty Articles and Research

Our intuitive concept of the relations between brain and mind is increasingly challenged by the scientific world view. Yet, although few neuroscientists openly endorse Cartesian dualism, careful reading reveals dualistic intuitions in prominent neuroscientific texts. Here, we present the “double-subject fallacy”: treating the brain and the entire person as two independent subjects who can simultaneously occupy divergent psychological states and even have complex interactions with each other—as in “my brain knew before I did.” Although at first, such writing may appear like harmless, or even cute, shorthand, a closer look suggests that it can be seriously misleading. Surprisingly, this confused …

Mechanisms And Molecular Biology Of Major Tumor Suppressors, Brienne E. Engel

USF Tampa Graduate Theses and Dissertations

This dissertation is devoted to the study of the molecular biology of major tumor suppressors, defined as those that prevent the cellular processes identified as the hallmarks of cancer. Specifically, the major tumor suppressors pRb and STK11 are explored in the context of osteosarcoma and lung cancer, respectively.

RB1 was the first tumor suppressor gene discovered. Over four decades of work have revealed that the Rb protein (pRb) is a master regulator of biological pathways influencing virtually every aspect of intrinsic cell fate including cell growth, cell-cycle checkpoints, differentiation, senescence, self-renewal, replication, genomic stability and apoptosis. While these many processes …

The Elaborated Intrusion Theory Of Desire: A 10-Year Retrospective And Implications For Addiction Treatments, Jon May, David J. Kavanagh, Jackie Andrade

School of Psychology

Ten years after the publication of Elaborated Intrusion (EI) Theory, there is now substantial research into its key predictions. The distinction between intrusive thoughts, which are driven by automatic processes, and their elaboration, involving controlled processing, is well established. Desires for both addictive substances and other desired targets are typically marked by imagery, especially when they are intense. Attention training strategies such as body scanning reduce intrusive thoughts, while concurrent tasks that introduce competing sensory information interfere with elaboration, especially if they compete for the same limited-capacity working memory resources. EI Theory has spawned new assessment instruments that are performing …

The Chanticleer, 2014-09-21, Coastal Carolina University

The Chanticleer Student Newspaper

The editorially independent student produced weekly newspaper of Coastal Carolina University.

Leadership In An Egalitarian Society, Christopher Von Rueden, Michael Gurven, Hillard Kaplan, Jonathan Stieglitz

ESI Publications

Leadership is instrumental to resolution of collective action dilemmas, particularly in large, heterogeneous groups. Less is known about the characteristics or effectiveness of leadership in small-scale, homogeneous, and relatively egalitarian societies, in which humans have spent most of our existence. Among Tsimane’ forager-horticulturalists of Bolivia, we (1) assess traits of elected leaders under experimental and naturalistic conditions and (2) test whether leaders impact collective action outcomes. We find that elected leaders are physically strong and have more kin and other exchange partners. Their ranks on physical dominance, kin support, and trustworthiness predict how well their groups perform, but only where …

Holy Cross Magazine, Vol. 48, No. 4, Fall 2014, College Of The Holy Cross

Holy Cross Magazine

Syllabus: Zen Buddhism
with Professor Todd Lewis
By Pamela Reponen

President’s Report: What Does the Magis Mean for Holy Cross Today?
Rev. Philip L. Boroughs, S.J., asked his vice presidents to reflect with him on how the Ignatian principle of the magis (“the more”) shapes lives.
Conversation photography by Patrick O’Connor

Opening a New Archive
Assistant Professor of English K.J. Rawson has embarked on a project that has never before been attempted: With a digital innovation fellowship from the American Council of Learned Societies, he will be creating the first transgender digital archive.
By Parker Marie Molloy
Photos by Rob …

An Expeditious Green Route Toward 2-Aryl-4- Phenyl-1h-Imidazoles, Debasish Bandyopadhyay, Lauren C. Smith, Daniel R. Garcia, Ram Naresh Yadav, Bimal K. Banik

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Background: Azaheterocycles are an important class of compounds because of their highly potent medicinal activities, and the imidazole subcategory is of special interest in regard to drug discovery research.

Findings: An expeditious synthetic protocol of 2-aryl-4-phenyl-1H-imidazoles has been accomplished by reacting phenylglyoxal monohydrate, ammonium acetate, and aldehyde under sonication. Following this green approach a series of 2-aryl-4-phenyl-1H-imidazoles has been synthesized using diversely substituted aldehydes.

Conclusions: A rapid and simple synthetic procedure to synthesize diversely substituted 2-aryl-4-phenyl-1H-imidazoles has been reported. Other salient features of this protocol include milder conditions, atom-economy, easy extraction, and minimum wastes. The present procedure may find application …

Evaluation Of Microarray-Based Dna Methylation Measurement Using Technical Replicates: The Atherosclerosis Risk In Communities (Aric) Study, Maitreyee Bose, Chong Wu, James S. Pankow, Ellen W. Demerath, Jan Bressler, Myriam Fornage, Megan L. Grove, Thomas H. Mosley, Chindo Hicks, Kari North, Wen Hong Kao, Yu Zhang, Eric Boerwinkle, Weihua Guan

Computer Science Faculty Publications

Background: DNA methylation is a widely studied epigenetic phenomenon; alterations in methylation patterns influence human phenotypes and risk of disease. As part of the Atherosclerosis Risk in Communities (ARIC) study, the Illumina Infinium HumanMethylation450 (HM450) BeadChip was used to measure DNA methylation in peripheral blood obtained from ~3000 African American study participants. Over 480,000 cytosine-guanine (CpG) dinucleotide sites were surveyed on the HM450 BeadChip. To evaluate the impact of technical variation, 265 technical replicates from 130 participants were included in the study.

Results: For each CpG site, we calculated the intraclass correlation coefficient (ICC) to compare variation of methylation levels …

English Studies + Stem: Envisioning A 21st Century Curriculum, Gwen Tarbox

Academic Leadership Academy

In 2013, the American Academy of Arts & Sciences established a commission to study the importance of integrating the STEM fields and the humanities in K-12 and higher education environments. The resulting report, entitled The Heart of the Matter, concluded that:

“Scientific advances have been critical to the extraordinary achievements of the past century, and we must continue to invest in basic and applied research in the biological and physical sciences. But...we must recognize that all disciplines are essential for the inventiveness, competitiveness, security, and personal fulfillment of the American public...The humanities remind us where we have been and help …

Science Reference Strategic Planning Process (University Libraries), Edward J. Eckel

Academic Leadership Academy

Science Reference serves:

College of Engineering and Applied Sciences

College of Health and Human Services

College of Arts and Sciences

• Biology
• Chemistry
• Environmental Studies
• Geosciences
• Mathematics
• Physics
• Statistics

We are a small department - three full-time librarians and one full-time evening coordinator.

Changing information world and student/faculty body: •More reference questions via email and chat •Fewer in-person reference questions •More librarian time spent on rich activities:

• Information Literacy instruction
• Committee and taskforce work
• Consultations/collaborations with faculty, staff, administrators

We began to ask ourselves: Is our current service …

Transformation Of Human Cathelicidin Ll-37 Into Selective, Stable, And Potent Antimicrobial Compounds., Guangshun Wang, Mark L. Hanke, Biswajit Mishra, Tamara Lushnikova, Cortney E. Heim, Vinai Chittezham Thomas, Kenneth W. Bayles, Tammy Kielian

Journal Articles: Pathology and Microbiology

This Letter reports a family of novel antimicrobial compounds obtained by combining peptide library screening with structure-based design. Library screening led to the identification of a human LL-37 peptide resistant to chymotrypsin. This d-amino-acid-containing peptide template was active against Escherichia coli but not methicillin-resistant Staphylococcus aureus (MRSA). It possesses a unique nonclassic amphipathic structure with hydrophobic defects. By repairing the hydrophobic defects, the peptide (17BIPHE2) gained activity against the ESKAPE pathogens, including Enterococcus faecium, S. aureus, Klebsiella pneumoniae, Acinetobacter baumanii, Pseudomonas aeruginosa, and Enterobacter species. In vitro, 17BIPHE2 could disrupt bacterial membranes and bind to DNA. In vivo, the peptide …

Discovering A Units’ Mission, David Rudge

Academic Leadership Academy

This poster discusses the importance of mission and vision statements and identifies considerations the Mallinson Institute might wish to consider as it develops its own mission statement in light of the University’s and the College of Arts & Sciences evolving missions.

An organization’s mission is a concise statement of why it exists, its reason for being. It is an enduring statement that usually remains the same for many years, providing long term direction and continuity for the organization. An organization’s vision describes the end state that it seeks to create. The development of mission and vision statements is an important …

Farm And Dairy Quotes Mccarthy On Chestnut's Chances, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Association Of Leukocyte Mitochondrial Dna Content With Glioma Risk: Evidence From A Chinese Case-Control Study., Jie Zhang, Deyang Li, Falin Qu, Yibing Chen, Gang Li, Hequn Jiang, Xiaojun Huang, Hushan Yang, Jinliang Xing

Department of Cancer Biology Faculty Papers

BACKGROUND: Increasing evidence suggests that alterations in mitochondrial DNA (mtDNA) content may be implicated in the tumorigenesis of several malignancies. However, the association between mtDNA content in peripheral blood lymphocytes (PBLs) and glioma risk has not been investigated.

METHODS: Real-time PCR was used to examine the mtDNA content in PBLs of 414 glioma patients and 414 matched controls in a hospital-based case-control study. The association between mtDNA content and glioma risk was evaluated using an unconditional multivariate logistic regression model.

RESULTS: We found that glioma patients exhibited a significantly higher median mtDNA content than healthy controls (0.99 vs. 0.71, P …

Novel Image Markers For Non-Small Cell Lung Cancer Classification And Survival Prediction, Hongyuan Wang, Fuyong Xing, Hai Su, Arnold J. Stromberg, Lin Yang

Statistics Faculty Publications

BACKGROUND: Non-small cell lung cancer (NSCLC), the most common type of lung cancer, is one of serious diseases causing death for both men and women. Computer-aided diagnosis and survival prediction of NSCLC, is of great importance in providing assistance to diagnosis and personalize therapy planning for lung cancer patients.

RESULTS: In this paper we have proposed an integrated framework for NSCLC computer-aided diagnosis and survival analysis using novel image markers. The entire biomedical imaging informatics framework consists of cell detection, segmentation, classification, discovery of image markers, and survival analysis. A robust seed detection-guided cell segmentation algorithm is proposed to accurately …

Medical Advances That Extend Human Lifespan Will Be Topic Of Forum, Staff

Browse All News

No abstract provided.

Daily Eastern News: September 19, 2014, Eastern Illinois University

September

No abstract provided.

Dimethyl Sulfoxide Damages Mitochondrial Integrity And Membrane Potential In Cultured Astrocytes, Chan Yuan, Junying Gao, Jichao Guo, Lei Bai, Charles Marshall, Zhiyou Cai, Linmei Wang, Ming Xiao

Center of Excellence in Rural Health Faculty Publications

Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective or neurotoxic agents in neuroscience research. However, DMSO itself also has pharmacological and pathological effects on the nervous system. Astrocytes play a central role in maintaining brain homeostasis, but the effect and mechanism of DMSO on astrocytes has not been studied. The present study showed that exposure of astrocyte cultures to 1% DMSO for 24 h did not significantly affect cell survival, but decreased cell viability and glial glutamate transporter expression, and caused mitochondrial swelling, membrane potential impairment and reactive oxygen species production, and subsequent cytochrome …

Comments On Some African Taxa Of Leptotyphlopid Snakes, Jeff Boundy

Occasional Papers of the Museum of Natural Science, Louisiana State University

Miscellaneous material of African Leptotyphlopidae are discussed: An overlooked senior synonym of Namibiana latifrons, mental scale characteristics in Tricheilostoma greenwelli, an insular record of Leptotyphlops pembae, a range expansion of Myriopholis adleri (new to the country of Ghana), and cephalic scale terminology of Rhinoleptus koniagui.

Agenda And Minutes, University Of South Florida St. Petersburg General Education Committee Meeting, September 19, 2014, University Of South Florida St. Petersburg. Faculty Senate. General Education Committee

USF St. Petersburg General Education Committee Meetings

Agenda and minutes from the September 19, 2014, meeting of the General Education Committee of the University of South Florida St. Petersburg's Faculty Senate.

Application Of High-Resolution Spectral Absorbance Measurements To Determine Dissolved Organic Carbon Concentration In Remote Areas, Armine Avagyan, Benjamin R. K. Runkle, Lars Kutzbach

Biological and Agricultural Engineering Faculty Publications and Presentations

Accurate quantification of dissolved organic carbon (DOC) in surface and soil pore waters is crucial for understanding changes in water resources under the influence of climate and land use changes. Sampling and laboratory analysis of DOC content at a sufficient temporal frequency are especially difficult to achieve for natural DOC sources like the extensive boreal and arctic mire landscapes due to their remoteness. Therefore, the goals of this paper are (1) to investigate the performance of a portable, high-resolution ultraviolet–visible light spectroscopic method for determining the DOC content of surface and soil pore water samples from a boreal mire complex …

The Distribution Pattern Of Halicephalobus Gingivalis In A Horse Is Suggestive Of A Haematogenous Spread Of The Nematode, Christina Henneke, Anna Jespersen, Stine Jacobsen, Martin K. Nielsen, Fintan Mcevoy, Henrik E. Jensen

Veterinary Science Faculty Publications

The majority of Halicephalobus gingivalis-infections in horses have been fatal and are usually not diagnosed before necropsy. Therefore, knowledge about the nematode and the pathogenesis of infection in horses is limited. This has resulted in an on-going discussion about the port of entry and subsequent dissemination of H. gingivalis within the host. The present case of H. gingivalis-infection in a horse was diagnosed ante mortem. Post mortem findings, the distribution pattern of H. gingivalis nematodes in the brain, a high prevalence of inflammation in close relation to blood vessels, and the presence of the nematode in multiple organs …

De Novo Assembly Of The Common Marmoset Transcriptome From Nextgen Mrna Sequences, Mnirnal D. Maudhoo, Dongren Ren, Julien S. Gradnigo, Robert M. Gibbs, Austin C. Lubker, Etsuko N. Moriyama, Jeffrey A. French, Robert B. Norgen Jr.

School of Biological Sciences: Faculty Publications

Background: Nonhuman primates are important for both biomedical studies and understanding human evolution. Although research in these areas has mostly focused on Old World primates, such as the rhesus macaque, the common marmoset (Callithrix jacchus), a New World primate, offers important advantages in comparison to other primates, such as an accelerated lifespan. To conduct Next Generation expression studies or to study primate evolution, a high quality annotation of the marmoset genome is required. The availability of marmoset transcriptome data from five tissues, including both raw sequences and assembled transcripts, will aid in the annotation of the newly released …

Trait-Based Diversification Shifts Reflect Differential Extinction Among Fossil Taxa, Peter J. Wagner, George F. Estabrook

School of Biological Sciences: Faculty Publications

Evolution provides many cases of apparent shifts in diversification associated with particular anatomical traits. Three general models connect these patterns to anatomical evolution: (i) elevated net extinction of taxa bearing particular traits, (ii) elevated net speciation of taxa bearing particular traits, and (iii) elevated evolvability expanding the range of anatomies available to some species. Traitbased diversification shifts predict elevated hierarchical stratigraphic compatibility (i.e., primitive→derived→highly derived sequences) among pairs of anatomical characters. The three specific models further predict (i) early loss of diversity for taxa retaining primitive conditions (elevated net extinction), (ii) increased diversification among …

Synthetic Life: Our Hybrid Future, Jenna Rickus

Dawn or Doom Conference

Several fields of science and engineering, including synthetic biology, neuroengineering, computer science, and nanotechnology, are working toward the creation of new forms of and modifications to life. This session will explore what we can do now to create synthetic life, what has already been done, and what we might do in the future. The session will include a discussion on possible frameworks for how science and society can responsibly move forward together.