Digital Commons Network^™

Identification Of High Responders For Interleukin-6 And Creatine Kinase Following Acute Eccentric Resistance Exercise In Elderly Obese Women, Vitor Tajra, Ramires Alsamir Tibana, Denis Cesar Leite Vieira, Darlan Lopes De Farias, Tatiane Gomes Teixeira, Silvana Schwerz Funghetto, Alessandro Oliviera Silva, Nuno Manuel Frade De Sousa, Jeffrey Willardson, Margo Gomes Oliviera Karnikowski, Jonato Prestes

Faculty Research and Creative Activity

Resistance exercise is used as a non-pharmacological tool to elicit both gains in and maintenance of physical function in the elderly. Thus, the present study examined the acute response of creatine kinase and interleukin-6 following an eccentric resistance exercise session in elderly obese women classified as high responders or normal responders.

Defining And Assessing Animal Pain, Lynne U. Sneddon, Robert W. Elwood, Shelley A. Adamo, Matthew C. Leach

Experimentation Collection

The detection and assessment of pain in animals is crucial to improving their welfare in a variety of contexts in which humans are ethically or legally bound to do so. Thus clear standards to judge whether pain is likely to occur in any animal species is vital to inform whether to alleviate pain or to drive the refinement of procedures to reduce invasiveness, thereby minimizing pain. We define two key concepts that can be used to evaluate the potential for pain in both invertebrate and vertebrate taxa. First, responses to noxious, potentially painful events should affect neurobiology, physiology and behaviour …

Monkey-Based Research On Human Disease: The Implications Of Genetic Differences, Jarrod Bailey

Laboratory Experiments Collection

Assertions that the use of monkeys to investigate human diseases is valid scientifically are frequently based on a reported 90–93% genetic similarity between the species. Critical analyses of the relevance of monkey studies to human biology, however, indicate that this genetic similarity does not result in sufficient physiological similarity for monkeys to constitute good models for research, and that monkey data do not translate well to progress in clinical practice for humans. Salient examples include the failure of new drugs in clinical trials, the highly different infectivity and pathology of SIV/HIV, and poor extrapolation of research on Alzheimer’s disease, Parkinson’s …

Utilizing Indicator Of Reduction In Soils Tubes To Affirm A Serpentinitic Hydric Soil On The California Central Coast, Jason Demoss

Natural Resources Management and Environmental Sciences

Wetlands are vital ecosystems that are crucial in maintaining the life of rare and unique soils, plants, and animals. These ecosystems are key players in water storage, water filtration, carbon storage, and harboring unique species. Since the intervention of human development on the Earth’s surface, almost 50% of the Earth’s original wetlands have either been damaged or destroyed. The identification and assessment of both new and old wetlands is crucial in the survival of these precious ecosystems and their conservation. A 3 month-long study was performed to confirm the hydric status of a soil derived from serpentinitic parent material. The …

Telemetry, November 2014, Mcnair Scholars Program (University Of Northern Iowa)

McNair Scholars Program at UNI Newsletter

Inside This Issue:
--Message from the Director Events
--Shout Out - Brittnie Dotson
--Graduate Student Mentor Program
--New Faces - Tigstu Woldeyohanns
--Shout Out - Vanessa Espinoza
--Writing the Personal Statement
--Contact Information

Winegrape Vineyards And Winery Operations: Energy Efficiency/ Sustainability And Expansion, Stuart Styles, Sierra Layous, Sarah Crable

BioResource and Agricultural Engineering

Southern California Edison (SCE) provides utility services to the greater southern California area. Vineyards and wineries exist throughout the region, and historical data suggests that that they largely do not utilize incentive programs offered by the utility.

As the first phase in a larger study, the Irrigation Training & Research Center (ITRC), located at the California Polytechnic State University, San Luis Obispo, completed a characterization of the vineyard and winery sector as it pertains to energy and water usage in SCE’s service area, including the following major tasks:

1. Identification of vineyard and winery demographics in SCE’s service area.
2. Identification of …

Multi-Modal, Surface-Focused Anticoagulation Using Poly-2-Methoxyethylacrylate Polymer Grafts And Surface Nitric Oxide Release, Surbhi Gupta, Kagya Amoako, Ahmed Suhaib, Keith E. Cook

Mechanical and Industrial Engineering Faculty Publications

This study examines platelet adhesion on surfaces that combine coatings to limit protein adsorption along with “anti-platelet” nitric oxide (NO) release. Uncoated and poly-2-methoxyethylacrylate (PMEA) coated, gas permeable polypropylene (PP) membranes were placed in a bioreactor to separate plasma and gas flows. Nitrogen with 100/500/1000 ppm of NO was supplied to the gas side as a proof of concept. On the plasma side, platelet rich plasma (PRP, 1 × 108 cell/mL) was recirculated at low (60)/high (300) flows (mL/min). After 8 hours, adsorbed platelets on PP was quantified via a lactate dehydrogenase assay. Compared to plain PP, the PMEA coating …

Using Detection Dogs And Genetic Analyses Of Scat To Expand Knowledge And Assist Felid Conservation In Misiones, Argentina, Karen E. Dematteo, Miguel A. Rinas, Carina F. Argüelles, Bernardo E. Holman, Mario S. Di Bitetti, Barbara Davenport, Patricia G. Parker, Lori S. Eggert

Biology Department Faculty Works

Many carnivores require large ranges to meet their ecological and energetic needs; however, anthropogenic changes threaten species and their habitats. Camera traps have been used to effectively collect data on carnivores in a variety of habitat types; however, a single survey effort is typically limited to species that have similar body size, habitat use and movement patterns, and individual identification of animals is not always possible. We evaluated whether scat detection dogs could effectively survey for 4 wide-ranging felids that vary in these characteristics: jaguars (Panthera onca), pumas (Puma concolor), ocelots (Leopardus pardalis) and oncillas (Leopardus tigrinus). From June to …

Novel Biomarkers Can Be Used As Targets To Combat Cancer, Harini Krishnan

Graduate School of Biomedical Sciences Theses and Dissertations

Cancer kills almost 8 million people per year worldwide. Therefore, about 13 people die from cancer every minute. Clearly, current cancer treatments are not completely effective. Moreover, many chemotherapeutic reagents are not very specific for cancer cells.

These agents attack rapidly dividing cells, including a wide array of normal cells, in addition to cancer cells, in the body. This lack of specificity can cause collateral damage and significant side effects in patients. More targeted therapies are needed to successfully combat cancer. Specific cancer biomarkers need to identified and characterized in order to develop better targeted anti-cancer drugs.

Tumor cells can …

Assessing The Ecological Impact Of The Western Rock Lobster Fishery In Fished And Unfished Areas Final Frdc Report – Project 2008/013, Lynda B. Bellchambers, Matthew B. Pember

Fisheries Research Reports

This project, in consultation with an industry working group, has been instrumental in establishing a closed area in the western rock lobster fishery to assess the potential ecosystem effects of removing lobster biomass from deep water (40-100 m). The major outcome of this research is an improved understanding of the ecosystem that supports the western rock lobster. These types of information for improve the Department of Fisheries’ ability to manage the fishery in an ecosystem based manner and provide scientifically defensible data to more precisely assess the level of risk of the fishery to deep water communities. In early 2013, …

Shark Bay Prawn Managed Fishery : Bycatch Action Plan : 2014 – 2019 : Version 1.0, Department Of Fisheries

Fisheries Management Papers

No abstract provided.

Fisheries Management Paper No.266 - Exmouth Gulf Prawn Managed Fishery Bycatch Action Plan 2014-2019. Version 1.0, Department Of Fisheries, Western Australia

Fisheries Management Papers

Bycatch is described as the part of the catch which is returned to the sea (usually referred to as non-retained or discarded) either because it has no commercial value or because legislative requirements preclude it being retained. Thus, this Bycatch Action Plan (BAP) includes unmarketable finfish and invertebrate species, along with endangered, threatened and protected (ETP) species, such as marine mammals, reptiles and some elasmobranchs.

It is Government policy to minimise bycatch in all commercial fisheries. This BAP details a program of actions to address bycatch issues in the Exmouth Gulf Prawn Managed Fishery (EGPMF), in accordance with the EGPMF …

Fisheries Management Paper No.265 - Exmouth Gulf Prawn Managed Fishery Harvest Strategy 2014 - 2019 Version 1.0, Department Of Fisheries Western Australia

Fisheries Management Papers

This fishery-specific harvest strategy has been developed in line with the Department of Fisheries' (Department) over-arching Harvest Strategy Policy for Aquatic Resources (Department of Fisheries in prep.) and in consultation with licensees. The broad scope of the Harvest Strategy Policy for Aquatic Resources is consistent with the National Harvest Strategy Guidelines but as well as considering all retained target species, it also incorporates retained non-target species, bycatch' and other ecological components to ensure the risks to these elements are managed effectively.

The Exmouth Gulf Prawn Managed Fishery (EGPMF) harvest strategy outlines the longand short-term fishery-specific management objectives; a description of …

The Effects Of Whole-Food Plant Based Diets On Ldl-C Levels In Adults, Jason Bryan

Graduate Research Projects

No abstract provided.

Older Adult Perceptions Of The Assist Program, Joy Anthony

Graduate Research Projects

No abstract provided.

Derivation And Validation Of Cutoffs For Clinical Use Of Cell Cycle Arrest Biomarkers, Eric A.J. Hoste, Peter A. Mccullough, Kianoush Kashani, Lakhmir S. Chawla, Michael Joannidis, The Sapphire Investigators

Anesthesiology and Critical Care Medicine Faculty Publications

Background

Acute kidney injury (AKI) remains a deadly condition. Tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein (IGFBP)7 are two recently discovered urinary biomarkers for AKI. We now report on the development, and diagnostic accuracy of two clinical cutoffs for a test using these markers.

Methods

We derived cutoffs based on sensitivity and specificity for prediction of Kidney Disease: Improving Global Outcomes Stages 2–3 AKI within 12 h using data from a previously published multicenter cohort (Sapphire). Next, we verified these cutoffs in a new study (Opal) enrolling 154 critically ill adults from six sites in the …

2014 Byu Law School Annual Report, J. Reuben Clark Law School

The BYU Advocate (& Annual Reports)

No abstract provided.

Analyzing The Interactions Between Xenopus Tropicalis Mc2r, Mc5r, And The Mraps: Modeling The Regulation Of Frog Interrenal Cells, Yesenia Garcia

Electronic Theses and Dissertations

The role of Melanocortin 2 Receptor (MC2R) in adrenal/interrenal glucocorticoid secretion has been well documented in many organisms. Studies in mammals have shown that in the adrenal gland two melanocortin receptors and two melanocortin receptor accessory proteins are expressed: MC2R, MC5R, MRAP, and MRAP2. The MRAPs have an opposite effect on the cell surface expression of MC2R and MC5R. In mammals, MRAP aids MC2R but inhibits MC5R cell surface expression. This thesis aims to explore the functional relationship between MC2R, MC5R, MRAP, and MRAP2 in Xenopus tropicalis to determine if the MRAPs have a similar effect on amphibian MC2R and …

Research & Strategic Partnerships: Quarterly Review, Volume 2, Issue 1, Portland State University. Research & Strategic Partnerships

Portland State Research Magazine

This Review describes connections among Portland State University, society's needs, and innovation: engineer Evan Thomas’s public health program in Rwanda, chemist Steve Reichow's protein research in the Collabo­rative Life Sciences Building, environmental historian Catherine McNeur's look back at urban agriculture in New York City, the "My Life" mentoring program for foster teens, and "Reclaiming Futures" interventions that help at-risk kids avoid incarceration.

It also focuses on EXITO. EXITO, Portland State University's largest-ever federal grant, awarded by the NIH to a team headed by Professors Carlos Crespo and Tom Keller. In the next decade, EXITO will help hundreds of underrepresented students …

Rgs16, A Novel P53 And Prb Cross-Talk Candidate Inhibits Migration And Invasion Of Pancreatic Cancer Cells, Miranda B. Carper, James Denvir, Goran Boskovic, Donald A. Primerano, Pier Paolo Claudio

Biochemistry and Microbiology

Data collected since the discovery of p53 and pRb/RB1 suggests these tumor suppressors cooperate to inhibit tumor progression. Patients who have mutations in both p53 and RB1 genes have increased tumor reoccurrence and decreased survival compared to patients with only one tumor suppressor gene inactivated. It remains unclear how p53 and pRb cooperate toward inhibiting tumorigenesis. Using RNA expression profiling we identified 179 p53 and pRb cross-talk candidates in normal lung fibroblasts (WI38) cells exogenously coexpressing p53 and pRb. Regulator of G protein signaling 16 (RGS16) was among the p53 and pRb cross-talk candidates and has been implicated in inhibiting …

College Of Arts And Sciences E-News Issue 19: November 2014, College Of Arts And Sciences

College of Arts and Sciences news

• University to honor its top four staffers for 2013-14 • WMU wins $779,072 grant, partners with Oxford in Web project • Constitution Day at WMU • Donald Southwell, 2014 Distinguished Alumnus • WMU taps alum, former K'zoo Public Safety officer as next police chief • Student Feature: Ted Carter • Student Recalls French Semester Abroad

Anorexia/Bulimia, Transcendence, And The Potential Impact Of Romanticized/Sexualized Death Imagery, Heather D. Schild

Center for the Study of Ethics in Society Papers

Presented November 10, 2014. Papers presented for the Center for the Study of Ethics in Society Western Michigan University

Goomig Farmlands Development Baseline Water Quality In The Lower Keep River, D L. Bennett, Richard J. George Dr

Resource management technical reports

In 2008 the Ord Irrigation Expansion Project was approved by the Western Australian Government to develop irrigated agriculture on the Weaber Plain. By mid-2014 construction of almost all of the water supply, drainage, access, monitoring and other infrastructure for the 7400ha Goomig Farmlands development had substantially been completed. An important concern is the effect the Goomig Farmlands development may have on the water quality of the downstream lower Keep River aquatic environment, particularly as it relates to threatened species that inhabit or may inhabit the area. Possible increases in salinity, nutrients, suspended sediment, heavy metals and farm chemicals delivered in …

Phylogenetic Analysis Of Algal Symbionts Associated With Four North American Amphibian Egg Masses, Eunsoo Kim, Yuan Lin, Ryan R. Kerney, Lili Blumenberg, Cory Bishop

Biology Faculty Publications

Egg masses of the yellow-spotted salamander Ambystoma maculatum form an association with the green alga “Oophila amblystomatis” (Lambert ex Wille), which, in addition to growing within individual egg capsules, has recently been reported to invade embryonic tissues and cells. The binomial O. amblystomatis refers to the algae that occur in A. maculatum egg capsules, but it is unknown whether this population of symbionts constitutes one or several different algal taxa. Moreover, it is unknown whether egg masses across the geographic range of A. maculatum, or other amphibians, associate with one or multiple algal taxa. To address these …

Stony Brook Press, V. 36, N. 03, Stony Brook University. Stony Brook Press.

Stony Brook Press

v. 36, n. 03, v.:ill. ; 38 cm (original analog pub.)

Atrx Is Required For Maintenance Of The Neuroprogenitor Cell Pool In The Embryonic Mouse Brain, Kieran Ritchie, L Ashley Watson, Benjamin Davidson, Yan Jiang, Nathalie G. Bérubé

Paediatrics Publications

Mutations in the alpha-thalassemia mental retardation X-linked (ATRX) gene cause a spectrum of abnormalities including intellectual disability, developmental delay, seizures, and microcephaly. The ATRX protein is highly enriched at heterochromatic repetitive sequences adjacent to the centromere, and ATRX depletion results in chromosome congression, segregation, and cohesion defects. Here, we show that Cre-mediated inactivation of Atrx in the embryonic mouse (Mus musculus) brain results in expansion of cerebral cortical layer VI, and a concurrent thinning of layers II-IV. We observed increased cell cycle exit during early-mid neurogenesis, and a depletion of apical progenitors by late neurogenesis in the Atrx-null neocortex, explaining …

Using A Public Health Approach To Understand “Skipping” Snowmobiles In Pangnirtung, Nunavut, Canada, Audrey R. Giles, Meghan Lynch, Gwenyth S. Stadig, Michelle Doucette Issaluk, Francine Darroch, Shaelyn Strachan

International Journal of Aquatic Research and Education

No abstract provided.

Non-Structural Program To Limit E. Coli Within Antelope Creek Lincoln, Nebraska, Jeffrey Polkowski

Community and Regional Planning Program: Professional Projects

Beginning in 2008, The City of Lincoln, Nebraska set forth efforts to reduce pollutant loads within Antelope Creek below U.S. Environmental Protection Agency (EPA) criteria with the goal of eventually having segments of the stream removed from the Clean Water Act 303(d) list of impaired waters. Early efforts focus on channel improvements made as part of the Antelope Valley Project to increase the flood carrying capacity of the Creek. However, additional funding is being provided through an intergovernmental agreement between the Nebraska Department of Environmental Quality and the City of Lincoln (Grant Number: 56-1283) to allow the City of Lincoln’s …

"To Collect Their Shattered Energies": Hammond Hospital And Military Mental Healthcare During The Civil War, Vinay Giri

Armstrong Undergraduate Journal of History

About the author
Vinay Giri is a Biology major at Duke University. While taking a global health class that explored the evolution of science and technology worldwide, he became very interested in the history of medicine. Vinay’s research was conducted in Beaufort, NC at the Duke Marine Lab.t

Adobe Medicus 2014 6 November-December, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.