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2014

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Synthetic, Sulfated, Lignin-Based Anticoagulants, Akul Mehta Jan 2014

Synthetic, Sulfated, Lignin-Based Anticoagulants, Akul Mehta

Theses and Dissertations

Chemoenzymatically synthesized low molecular weight lignin polymers have been previously found to be potent inhibitors of a number of serine proteases via allosteric mechanisms targeting heparin binding sites. Herein, we describe the creation of synthetic sulfated β-O4 lignin (SbO4L) polymer, which is more homogenous compared to previous lignins with respect to its inter-monomeric linkage. SbO4L is a selective inhibitor of thrombin and plasmin. SbO4L was found to act via a unique mechanism targeting thrombin exosite 2 in a manner similar to platelet glycoprotein Ibα (GPIbα). Advanced hemostasis and thrombosis assays demonstrated that SbO4L acts via a dual mechanism: as an …


Platinum Complexes And Zinc Finger Proteins: From Target Recognition To Fixation, Samantha Tsotsoros Jan 2014

Platinum Complexes And Zinc Finger Proteins: From Target Recognition To Fixation, Samantha Tsotsoros

Theses and Dissertations

Bioinorganic chemistry strives to understand the roles of metals in biological systems, whether in the form of naturally occurring or addition of non-essential metals to natural systems. Metal ions play vital roles in many cellular functions such as gene expression/regulation and DNA transcription and repair. The study of metal-protein-DNA/RNA interactions has been relatively unexplored. It is important to understand the role of metalloprotein interactions with DNA/RNA as this enhanced knowledge may lead to better understanding of diseases and therefore more effective treatments. A major milestone in the development of this field was the discovery of the cytotoxic properties of cisplatin …


Regulation Of Ykl-40 In Sterile Inflammation And Its Role In Glioblastoma In Vivo, Reetika Bhardwaj Jan 2014

Regulation Of Ykl-40 In Sterile Inflammation And Its Role In Glioblastoma In Vivo, Reetika Bhardwaj

Theses and Dissertations

YKL-40 is a secreted glycoprotein, which is a shared biomarker of chronic inflammation and oncogenic transformation. Indeed, YKL-40 expression is up-regulated in many diseases including multiple sclerosis, Alzheimer disease, viral encephalitis, HIV-associated dementia, brain infarction, and traumatic brain injury. YKL-40 is also expressed by several solid tumors, such as osteosarcoma, ovarian carcinoma and glioblastoma multiforme (GBM). It promotes the migration and invasion of astrocytes as well as GBM cells. Serum YKL-40 levels have been shown to directly correlate with tumor grade and potentially tumor burden in GBM. In contrast to the numerous reports documenting elevated expression of YKL-40, relatively little …


Developing A Caenorhabditis Elegans Model For Marfan Syndrome, Pauline Fotopoulos Jan 2014

Developing A Caenorhabditis Elegans Model For Marfan Syndrome, Pauline Fotopoulos

Theses and Dissertations

Marfan Syndrome (MFS) is one of the most common monogenic diseases and affects approximately 1 in 5,000 individuals worldwide. The syndrome is characterized by elongated extremities, tall stature, slender frame, and cardiac, and vision abnormalities due to severe connective tissue defects. It is caused by mutations in the fbn1 gene, which encodes an extracellular matrix glycoprotein, and is required for proper cardiac and skeletal development and for sequestration of TGFβ (transforming growth factor beta) and BMP (bone morphogenetic protein) within the extracellular matrix (ECM). The primary objective of this study was to establish a C.elegans MFS model and use this …


Global Assessment Of Radiocarbon Isotopic Analysis For Particulate And Dissolved Organic Carbon In Riverine Systems, Ashley Tucker Jan 2014

Global Assessment Of Radiocarbon Isotopic Analysis For Particulate And Dissolved Organic Carbon In Riverine Systems, Ashley Tucker

Theses and Dissertations

Rivers are a significant source of particulate and dissolved organic carbon (POC, DOC) into inland waters and coastal systems and provide a fundamental linkage between the terrestrial, oceanic, and atmospheric carbon reservoirs. Recent studies have examined the relationship between the quantity and form (POC vs. DOC) of carbon delivered to the aquatic system; however, little is known about the age of POC and DOC exported and how the radiocarbon age may vary with latitude, topographic gradient, vegetation, and land use. I provide the first global synthesis of published radiocarbon values of POC and DOC (∆14C). Inclusion of DOC and POC …


2014 Weed Science Research Report – Gold Section, Ndsu Weed Science, Dept. Of Plant Sciences Jan 2014

2014 Weed Science Research Report – Gold Section, Ndsu Weed Science, Dept. Of Plant Sciences

Plant Sciences Weed Science Reports

The Weed Science team at North Dakota State University conduct field research in the State of North Dakota. This specific document reports on field research conducted in 2014. It includes work on sugarbeet and the management of several weeds in North Dakota.


Speleomycological Research In Underground Osówka Complex In Sowie Mountains (Lower Silesia, Poland), Wojciech Pusz, Rafał Ogórek, Cecylia Miłowana Uklańska-Pusz, Paweł Zagożdżon Jan 2014

Speleomycological Research In Underground Osówka Complex In Sowie Mountains (Lower Silesia, Poland), Wojciech Pusz, Rafał Ogórek, Cecylia Miłowana Uklańska-Pusz, Paweł Zagożdżon

International Journal of Speleology

Osówka (Germ. Säuferhöhen), is one of the elements of the unfinished Nazi military complex called “Riese”. The total length of corridors of Osówka complex is about 1,700 m and its capacity amounts to 30,000 m3. As described geologically, Osówka is situated within the Sowie Mts. Massif which consists mostly of various gneisses with different structural characteristics, but with a constant mineral composition. The rock-forming minerals are feldspar (oligoclase), quartz, biotite and light micas, accesory minerals are garnet, sillimanite and dysten. Fine-grained shallow-sea deposits were probably a protolith of these rocks. The study aimed at first mycological evaluation of …


Influence Of Soil On Groundwater Geochemistry In A Carbonate Aquifer, Southern Italy, Tiziano Boschetti, Antonio Falasca, Antonio Bucci, Vincenzo De Felice, Gino Naclerio, Fulvio Celico Jan 2014

Influence Of Soil On Groundwater Geochemistry In A Carbonate Aquifer, Southern Italy, Tiziano Boschetti, Antonio Falasca, Antonio Bucci, Vincenzo De Felice, Gino Naclerio, Fulvio Celico

International Journal of Speleology

The role of soil compositions in influencing groundwater geochemistry in carbonate aquifers is still little known. Nothing is known regarding the influence of pyroclastic soils (andisol) within the carbonate Apennines in central-southern Italy, despite their wide distribution. In this study we analyze some physical and chemical properties of pyroclastic soil at the Acqua dei Faggi experimental site (southern Italy), to assess its influence on groundwater geochemistry. Chemical analyses were carried out on saturated paste extracts and a physical analogue model was developed through two column experiments. Physico-chemical properties of rainwater and spring water, and some microbiological features of the soil …


The Conservation Value Of Karst Dolines For Vascular Plants In Woodland Habitats Of Hungary: Refugia And Climate Change, Zoltán Bátori, János Csiky, Tünde Farkas, E. Anna Vojtkó, László Erdős, Dániel Kovács, Tamás Wirth, László Körmöczi, András Vojtkó Jan 2014

The Conservation Value Of Karst Dolines For Vascular Plants In Woodland Habitats Of Hungary: Refugia And Climate Change, Zoltán Bátori, János Csiky, Tünde Farkas, E. Anna Vojtkó, László Erdős, Dániel Kovács, Tamás Wirth, László Körmöczi, András Vojtkó

International Journal of Speleology

Limestone (karst) surfaces in Hungary are rich in dolines, in which many endangered vascular plant species occur. To date, the majority of studies dealing with doline vegetation have focused on the local rather than the landscape level, without using comparative data from other areas. However, in this study we aimed to compare the vegetation pattern and species composition of dolines under different climate regimes of Hungary with regard to regional species pools. The fieldwork was carried out between 2005 and 2012. Twenty dolines were selected in the Mecsek Mountains (southern Hungary) and nine dolines in the Aggtelek Karst area (northern …


Identification And Ss-Lactam Resistance In Aquatic Isolates Of Enterobacter Cloacae And Their Status In Microbiota Of Domica Cave In Slovak Karst (Slovakia), Barbora Gaalova, Alena Donauerova, Milan Seman, Helena Bujdakova Jan 2014

Identification And Ss-Lactam Resistance In Aquatic Isolates Of Enterobacter Cloacae And Their Status In Microbiota Of Domica Cave In Slovak Karst (Slovakia), Barbora Gaalova, Alena Donauerova, Milan Seman, Helena Bujdakova

International Journal of Speleology

Domica Cave is located in the Slovak Karst National Park in southern Slovakia. Heterotrophic cultivable psychrophilic and mesophilic microbiota were confirmed to be prevalent in this cave. Escherichia coli was the most abundant bacterium, followed by Enterobacter species and Serrratia species. Enterobacter cloacae isolates belong to the group of faecal contaminants (coliforms) of concern in water. Their status in cave ecosystem is questionable, but we observed E. cloacae in water samples all years round suggesting an autochthonous origin. We were concerned with possible contamination of the cave water with resistant E. cloacae from animal farms located 2-3 km from the …


Upper Pleistocene And Holocene Palaeoenvironmental Records In Cueva Mayor Karst (Atapuerca, Spain) From Different Proxies: Speleothem Crystal Fabrics, Palynology And Archaeology., Virginia Martínez-Pillado, Arantza Aranburu, Juan Luis Arsuaga, Blanca Ruiz-Zapata, Maria José Gil-García, Heather Stoll, Iñaki Yusta, Eneko Iriarte, José Miguel Carretero, R. Lawrence Edwards, Hai Cheng Jan 2014

Upper Pleistocene And Holocene Palaeoenvironmental Records In Cueva Mayor Karst (Atapuerca, Spain) From Different Proxies: Speleothem Crystal Fabrics, Palynology And Archaeology., Virginia Martínez-Pillado, Arantza Aranburu, Juan Luis Arsuaga, Blanca Ruiz-Zapata, Maria José Gil-García, Heather Stoll, Iñaki Yusta, Eneko Iriarte, José Miguel Carretero, R. Lawrence Edwards, Hai Cheng

International Journal of Speleology

The Cueva Mayor karst system of Atapuerca, in Northern Spain, hosts a highly significant record of human occupation from the Pleistocene. The climatic context of the human activities during the Pleistocene-Holocene for this inland site has not been well constrained, since existing records of the palaeoclimatic evolution of the Northern Iberian Peninsula are from more distal coastal and high-elevation sites. In this study, we interpret the palaeoenvironmental information recorded on the petrography of a stalagmite and the pollen spectra of the Sierra de Atapuerca karst system during the last 20 kyr. The integration of both types of records has allowed …


Full Issue 43(1) Jan 2014

Full Issue 43(1)

International Journal of Speleology

No abstract provided.


Plant Inhabiting Phytoseiid Predators Of Midwestern Brazil, With Emphasis On Those Associated With The Tomato Red Spider Mite, Tetranychus Evansi (Acari: Phytoseiidae, Tetranychidae), Imeuda P. Furtado, Gilberto José De Moraes, Serge Kreiter, Carlos H.W. Flechtmann, Marie Stéphanne Tixier, Markus Knapp Jan 2014

Plant Inhabiting Phytoseiid Predators Of Midwestern Brazil, With Emphasis On Those Associated With The Tomato Red Spider Mite, Tetranychus Evansi (Acari: Phytoseiidae, Tetranychidae), Imeuda P. Furtado, Gilberto José De Moraes, Serge Kreiter, Carlos H.W. Flechtmann, Marie Stéphanne Tixier, Markus Knapp

All Peer-Reviewed Publications

The fauna of phytoseiid mites in the state of Mato Grosso do Sul, in midwestern Brazil, is poorly known. The tomato red spider mite, Tetranychus evansi Baker and Pritchard, is an important pest of Solanaceae in several countries, but it is usually found in low densities in Brazil. It has been hypothesized that this is due to the effect of natural enemies. The objective of this study was to identify phytoseiid mites from Mato Grosso do Sul associated with T. evansi, to identify promising biological control agents for T. evansi in Africa. A survey was conducted in October – November …


Biology Of The Coconut Bug, Pseudotheraptus Wayi, On French Beans, James Peter Egonyu, Sunday Ekesi, Jacques Kabaru, Lucy Irungu Jan 2014

Biology Of The Coconut Bug, Pseudotheraptus Wayi, On French Beans, James Peter Egonyu, Sunday Ekesi, Jacques Kabaru, Lucy Irungu

All Peer-Reviewed Publications

The coconut bug, Pseudotheraptus wayi Brown (Heteroptera: Coreidae), is a major pest of a wide range of economically important crops in Eastern and Southern Africa. The suitability of French beans, Phaseolus vulgaris L. (Fabales: Fabaceae) as an alternative food for mass rearing of P. wayi was determined by elucidating its development, survival, and reproduction on French bean pods in the laboratory. Development and survival of immatures on French beans was comparable to what is reported with two hosts previously used for rearing this species, namely coconut and cashew. Adults survived thrice longer and laid almost twice more eggs on the …


Photonic Crystal Fiber Half-Taper Probe Based Refractometer, Pengfei Wang, Ming Ding, Lin Bo, Chunying Guan, Yuliya Semenova, Weimin Sun, Libo Yuan, Gilberto Brambilla, Gerald Farrell Jan 2014

Photonic Crystal Fiber Half-Taper Probe Based Refractometer, Pengfei Wang, Ming Ding, Lin Bo, Chunying Guan, Yuliya Semenova, Weimin Sun, Libo Yuan, Gilberto Brambilla, Gerald Farrell

Articles

A compact singlemode - photonic crystal fibre - singlemode fibre tip (SPST) refractive index sensor is demonstrated in this paper. A CO2 laser cleaving technique is utilsed to provide a clean-cut fibre tip which is then coated by a layer of gold to increase reflection. An average sensitivity of 39.1 nm/RIU and a resolvable index change of 2.56×10-4 are obtained experimentally with a ~3.2 µm diameter SPST. The temperature dependence of this fiber optic sensor probe is presented. The proposed SPST refractometer is also significantly less sensitive to temperature and an experimental demonstration of this reduced sensitivity is …


Meta-Analysis Of Herbal Cannabis Therapy For Chronic Pain, Michael J. Seneca Jan 2014

Meta-Analysis Of Herbal Cannabis Therapy For Chronic Pain, Michael J. Seneca

UNF Graduate Theses and Dissertations

Since the first so-called “medical marijuana” legislation was passed in California in 1996, a total of twenty states and the District of Columbia have passed laws permitting limited use of cannabis. Despite the changes in state laws, cannabis remains illegal for any purpose under federal law. Changes in state laws have coincided with a renewed interest in the substance for the treatment of a variety of conditions. There has been a significant increase in published data over the past twenty years examining the efficacy of cannabis as an appetite stimulant, antiemetic agent, and analgesic adjuvant. The purpose of this meta-analysis …


Holographic Sensors: Three-Dimensional Analyte-Sensitive Nanostructures And Their Applications, Ali K. Yetisen, Izabela Naydenova, Fernando Da Cruz Vasconcellos, Jeffrey Blyth, Christopher R. R. Lowe Jan 2014

Holographic Sensors: Three-Dimensional Analyte-Sensitive Nanostructures And Their Applications, Ali K. Yetisen, Izabela Naydenova, Fernando Da Cruz Vasconcellos, Jeffrey Blyth, Christopher R. R. Lowe

Articles

Holographic sensors are analytical devices that systematically diffract narrow-band light in the ultraviolet to near-infrared range for application in the detection and quantification of analytes and/or physical parameters. They can be functionalized with analyte-responsive materials to construct highly sensitive optical sensors for use in testing, where a visual readout, fast turnaround time, and reversibility are needed. Holography allows fabrication of disposable sensors that are lightweight for miniaturization and multiplexing purposes.3 Holographic sensors offer three capabilities on a single analytical device: (i) label-free analyte-responsive polymer, (ii) real-time, reversible quantification of the external stimuli, and (iii) three-dimensional visual image display.


Adaptive Wetland Management In An Uncertain And Changing Arid Environment, Rebekah Downward, Joanna Endter-Wada, Karin M. Kettenring Jan 2014

Adaptive Wetland Management In An Uncertain And Changing Arid Environment, Rebekah Downward, Joanna Endter-Wada, Karin M. Kettenring

Environment and Society Faculty Publications

Wetlands in the arid western United States provide rare and critical migratory bird habitat and constitute a critical nexus within larger social-ecological systems (SES) where multiple changing land-use and water-use patterns meet. The Bear River Migratory Bird Refuge in Utah, USA, presents a case study of the ways that wetland managers have created adaptive management strategies that are responsive to the social and hydrological conditions of the agriculture-dominated SES within which they are located. Managers have acquired water rights and constructed infrastructure while cultivating collaborative relationships with other water users to increase the adaptive capacity of the region and decrease …


Ethnic Variation In Breastfeeding And Complementary Feeding In The Republic Of Ireland, Patricia Castro, Richard Layte, John Kearney Jan 2014

Ethnic Variation In Breastfeeding And Complementary Feeding In The Republic Of Ireland, Patricia Castro, Richard Layte, John Kearney

Articles

Early nutrition plays a pivotal role in long-term health. The World Health Organization (WHO) recommends exclusive breastfeeding during the first six months of life, with the gradual introduction of solids after this period. However, studies in the Republic of Ireland (ROI) have shown poor compliance with guidelines. The ROI continues to have one of the lowest breastfeeding rates worldwide. Our objective was to analyse differences in breastfeeding and complimentary feeding behaviours between Irish and non-Irish mothers residing in the ROI, as well as the role of acculturation on these behaviours, using the national longitudinal study, Growing Up in Ireland (GUI). …


Pilot Data On Brain-To-Blood Efflux Of B-Amyloid Peptides In Man, Steve Meaney, Maura Heverin, Ingemar Bjorkhem,, Dorotea Religa, John Wahren, Ulf Diczfalusy Jan 2014

Pilot Data On Brain-To-Blood Efflux Of B-Amyloid Peptides In Man, Steve Meaney, Maura Heverin, Ingemar Bjorkhem,, Dorotea Religa, John Wahren, Ulf Diczfalusy

Articles

• Alzheimer’s disease (AD) is the most common cause of dementia and affects nearly 40,000 individuals in Ireland. • The b-amyloid peptide (Ab) plays a key role in the pathogenesis of the AD and the presence of Ab plaques in the brain is diagnostic. •The hypothesis posits that Ab deposition is a critical factor in the disease process and that production and clearance of Ab are key drivers of the disease1. •Flux of Ab from the brain is believed to contribute to the overall level of Ab within in brain2 and antibody mediated brain-to-blood efflux has been observed in animal …


Modeling Of Aqueous Equilibrium: Three-Dimensional Trend Surfaces (Topos), Mohammad Mainul Hossain Jan 2014

Modeling Of Aqueous Equilibrium: Three-Dimensional Trend Surfaces (Topos), Mohammad Mainul Hossain

Graduate Student Theses, Dissertations, & Professional Papers

This dissertation establishes a comprehensive approach to looking at aqueous equilibria phenomena over essentially all feasible compositions of two component solutions - acid-base titrations, metal-ligand complexation, oxidation-reduction couples and solubility of binary ionic compounds. Fundamental to this method is the definition of a composition grid above which numerous system properties can be plotted as three-dimensional trend surfaces to visualize important aspects of system behavior. These have been named "topos" because their appearance is similar to topographic maps. In each case Microsoft ExcelTM worksheets have been designed with embedded Visual BasicTM macros that provide an easy means for anyone to generate …


2014 Big Data Conference Program, Big Data Conference Jan 2014

2014 Big Data Conference Program, Big Data Conference

2014 Conference Presentations

No abstract provided.


The Politics Of Melancholy In Alfonso Cuarón’S Y Tu Mamá También, Children Of Men And The Possibility Of Hope, Jessica Anderson Jan 2014

The Politics Of Melancholy In Alfonso Cuarón’S Y Tu Mamá También, Children Of Men And The Possibility Of Hope, Jessica Anderson

Graduate Student Theses, Dissertations, & Professional Papers

This thesis examines how three films directed by Alfonso Cuarón, Y Tu Mamá También, Children of Men, and The Possibility of Hope, represent the impact of globalization on society and the environment. These films are thematically related, and intended to be considered in connection with one another, as indicated by both interviews with Cuarón, and by critical commentary informing audience reception of these works. Each film uses melancholy as a plot device, and as an ambient presence to elucidate Cuarón’s underlying message that we must re-examine the problematic social, economic and environmental consequences of neo-liberal capitalist models of globalization. Melancholy …


Theophylline And Ambrisentan Combination: Effects On Human Performance, Ams And Physiological Responses To Altitude, Hilary Linda Palakovich Jan 2014

Theophylline And Ambrisentan Combination: Effects On Human Performance, Ams And Physiological Responses To Altitude, Hilary Linda Palakovich

Graduate Student Theses, Dissertations, & Professional Papers

Recent research efforts have attempted to determine the effectiveness of the combination of a pharmacological cardiac stimulant (theophylline) and pulmonary vasodilator (ambrisentan) in attenuating performance losses and mountain sickness at altitude. This combination has been observed to improve hypoxic exercise performance in rats, but never tested in human subjects. In the current study, 30 male participants were tested in a paired fashion to assess whether this drug combination would improve exercise performance and/or decrease symptoms of AMS. The experimental group (EXP, n = 15) received a treatment of 400 mg theophylline and 5 mg ambrisentan, while the placebo group (PLA, …


Use Of A Forest Reconstruction Model To Assess Changes To Sierra Nevada Mixed-Conifer Forest Conditions During The Fire Suppression Era, Molly Augusta Frederica Barth Jan 2014

Use Of A Forest Reconstruction Model To Assess Changes To Sierra Nevada Mixed-Conifer Forest Conditions During The Fire Suppression Era, Molly Augusta Frederica Barth

Graduate Student Theses, Dissertations, & Professional Papers

Fire suppression has resulted in dramatic changes to species composition and structural diversity in the Sierra Nevada mixed-conifer forests of California. Advancing the ecological understanding and management of these forests requires a better understanding of changes that occurred during the fire suppression era, but empirical historical datasets are rare and methodologies for developing new historical reference information are subject to many limitations. I sought to develop historical reference information for the Yosemite Forest Dynamics Plot (YFDP), a research plot located in an old-growth mixed-conifer stand in Yosemite National Park. I performed a dendrochronological fire history analysis to characterize the historical …


21st-Century U.S. Safety Professional Educational Standards: Establishing Minimum Baccalaureate Graduate Learning Outcomes For Emerging Occupational Health And Safety Professionals, Wayne Edward Hartz Jan 2014

21st-Century U.S. Safety Professional Educational Standards: Establishing Minimum Baccalaureate Graduate Learning Outcomes For Emerging Occupational Health And Safety Professionals, Wayne Edward Hartz

Antioch University Dissertations & Theses

How can the public be assured of competency in those professing to protect its occupational health and safety (OSH)? Currently, in the U.S. there are 193 higher education OSH programs, 186 with baccalaureate degrees with over 55 different degree titles. This research seeks to define minimum OSH baccalaureate graduate core competencies across all programs by asking: What would employers look for in a portfolio to demonstrate competence in a new OSH graduate? Professional members of the American Society of Safety Engineers (ASSE) participated as subject matter experts in an anonymous online survey to provide framing data. The ASSE Educational Standards …


Knowing The Indigenous Leadership Journey: Indigenous People Need The Academic System As Much As The Academic System Needs Native People, Dawn Elizabeth Hardison-Stevens Jan 2014

Knowing The Indigenous Leadership Journey: Indigenous People Need The Academic System As Much As The Academic System Needs Native People, Dawn Elizabeth Hardison-Stevens

Antioch University Dissertations & Theses

This dissertation explores the research question, “How can we create the best learning environments for Indigenous students through good leadership at all levels?” A bridge between cultures provides learning opportunities toward academic success between Indigenous students, families, leaders, and communities. Through personal experience as a practitioner, professional, and education, my research examines and identifies results from personnel and students at five schools, tribal and public, their tribal communities, and two Indigenous people in high profile leadership positions indicating an educational philosophy recognizing Indigenous people need the academic system as much as the academic system needs Native people. Portraits and interviews …


Wise By Design: A Wisdom-Based Framework For Innovation And Organizational Design And Its Potential Application In The Future Of Higher Education, Juan Francisco Suarez Jan 2014

Wise By Design: A Wisdom-Based Framework For Innovation And Organizational Design And Its Potential Application In The Future Of Higher Education, Juan Francisco Suarez

Antioch University Dissertations & Theses

A wiser socio-economic system, by design and not by chance, may well benefit from a series of design principles drawn from the well of wisdom. This dissertation focused on a refined set of eight components of wisdom through research designed to explore if, how, and when they are invoked by a group of experts participating in a futures discussion about organizations in their field of practice, American higher education. The aim was to explore a set of wisdom-centered design principles (denoted as Wise By Design [WBD]) for social innovation, specifically in the design of organizations that would thrive in the …


Psychotherapy And The Embodiment Of The Neuronal Identity: A Hermeneutic Study Of Louis Cozolino's (2010) The Neuroscience Of Psychotherapy: Healing The Social Brain , Ari Simon Natinsky Jan 2014

Psychotherapy And The Embodiment Of The Neuronal Identity: A Hermeneutic Study Of Louis Cozolino's (2010) The Neuroscience Of Psychotherapy: Healing The Social Brain , Ari Simon Natinsky

Antioch University Dissertations & Theses

In recent years, there have been several ways in which researchers have attempted to integrate psychotherapy and neuroscience research. Neuroscience has been proposed as a method of addressing lingering questions about how best to integrate psychotherapy theories and explain their efficacy. For example, some psychotherapy outcome studies have included neuroimaging of participants in order to propose neurobiological bases of effective psychological interventions (e.g., Paquette et al., 2003). Other theorists have used cognitive neuroscience research to suggest neurobiological correlates of various psychotherapy theories and concepts (e.g., Schore, 2012). These efforts seem to embody broader historical trends, including the hope that neuroscience …


Portraits Of Vocal Psychotherapists: Singing As A Healing Influence For Change And Transformation, Susan G. Summers Jan 2014

Portraits Of Vocal Psychotherapists: Singing As A Healing Influence For Change And Transformation, Susan G. Summers

Antioch University Dissertations & Theses

The purpose of this study was to explore the personal singing and vocal journey of music therapists who are also trained as vocal psychotherapists with the Austin model of vocal psychotherapy. I was interested in learning how singing has been a healing influence for change and transformation in their lives. It is my hope that this research will offer music therapists new perspectives and information about how singing is important in healing for their own change and transformation, and for that of their clients. This research also may have implications for leaders of change as well as those who engage …