Digital Commons Network^™

‘Perhaps Aliens Have Stolen Your Creativity?’ Alumni Have The Answer, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Agenda And Minutes, University Of South Florida St. Petersburg General Education Committee Meeting, November 14, 2014, University Of South Florida St. Petersburg. Faculty Senate. General Education Committee

USF St. Petersburg General Education Committee Meetings

Agenda and minutes from the November 14, 2014, meeting of the General Education Committee of the University of South Florida St. Petersburg's Faculty Senate.

The New Hampshire, Vol. 104 [105], No. 18 (Nov. 14, 2014), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 104, but it is the 105th volume in the series. This was corrected in pencil.

A Comparison Of The Caulobacter Na1000 And K31 Genomes Reveals Extensive Genome Rearrangements And Differences In Metabolic Potential, Craig Stephens, Kurt Ash, Theta Brown, Tynetta Watford, Latia E. Scott, Bert Ely

Biology

The genus Caulobacter is found in a variety of habitats and is known for its abilityto thrive in low-nutrient conditions. K31 is a novel Caulobacter isolate that has the ability to tolerate copper and chlorophenols, and can grow at 48Cwith a doubling time of 40 h. K31 contains a 5.5 Mb chromosome that codes for more than 5500 proteins and two large plasmids (234 and 178 kb) thatcode for 438 additional proteins. A comparison of the K31 and the Caulobactercrescentus NA1000 genomes revealed extensive rearrangements of gene order,suggesting that the genomes had been randomly scrambled. However, a careful analysis revealed …

An Exploration Of Human Sustainability: Guiding Undergraduates Onto A Path Of Responsive World Citizenship Through The Study Of Global Issues, Phyllis Duryee, Barry Adams

Learning Showcase 2014

This poster presentation will frame the primary research arenas for undergraduate study within the realm of continuing and emerging human and environmental struggles that occur broadly and locally in our 21st century globalized world. The research underscores the interdependence of human societies and the development of a sense of self and appreciation of cultural diversity, an affirmation of equality and justice, and an awareness of the absolute necessity of universal human rights as a foundation for the sustainability of our planet and world understanding.

Through the investigative lens of one country, each student studies the forces of economic, financial, cultural, …

Genomic Sequencing Data Analysis Workflow For Bioinformatics Core Facilities, Selen A. Yilmaz, Jie Zhang, Gulcin Ozer

Learning Showcase 2014

Next Generation Sequencing (NGS) is becoming a common tool in the practice of biomedical research and the future of how medicine will be practiced. To keep up with the explosion in new NGS experiments and the growing need in data analysis, we identified bottlenecks of our NGS data analysis workflow, evaluated and tested feasibility of solutions. To address main bottlenecks we incorporated two solutions into our

workflow: (1) Globus Genomics, a well-maintained cloud based sequencing data analysis framework which leverage advanced tools and data management, and (2) GenomAnalytics from GenomOncology, an interactive platform for data integration, annotation, filtering an interpretation. …

Barghi, Ryder In The Running For International Academic Honors, Staff

Browse All News

No abstract provided.

Choroid Plexus In Developmental And Evolutionary Perspective, Brent Roy Bill, Vladimir Korzh

Biology Faculty Publications and Presentations

The blood-cerebrospinal fluid boundary is present at the level of epithelial cells of the choroid plexus. As one of the sources of the cerebrospinal fluid (CSF), the choroid plexus (CP) plays an important role during brain development and function. Its formation has been studied largely in mammalian species. Lately, progress in other model animals, in particular the zebrafish, has brought a deeper understanding of CP formation, due in part to the ability to observe CP development in vivo. At the same time, advances in comparative genomics began providing information, which opens a possibility to understand further the molecular mechanisms involved …

Crystal Structure Of A Lipoxygenase In Complex With Substrate: The Arachidonic Acid-Binding Site Of 8r-Lipoxygenase, David B. Neau, Gunes Bender, William E. Boeglin, Sue G. Bartlett, Alan R. Brash, Marcia E. Newcomer

Faculty Publications

Lipoxygenases (LOX) play critical roles in mammalian biology in the generation of potent lipid mediators of the inflammatory response; consequently, they are targets for the development of isoform-specific inhibitors. The regio- and stereo-specificity of the oxygenation of polyunsaturated fatty acids by the enzymes is understood in terms of the chemistry, but structural observation of the enzyme-substrate interactions is lacking. Although several LOX crystal structures are available, heretofore the rapid oxygenation of bound substrate has precluded capture of the enzyme-substrate complex, leaving a gap between chemical and structural insights. In this report, we describe the 2.0 Å resolution structure of 8R-LOX …

“Just As Bad As Prisons”: The Challenge Of Dismantling The School-To-Prison Pipeline Through Teacher And Community Education, Quaylan Allen, Kimberly A. White-Smith

Education Faculty Articles and Research

Drawing upon the authors’ experiences working in schools as teachers, teacher educators, researchers, and community members, this study utilizes a Critical Race Theory of education in examining the school-to-prison pipeline for black male students. In doing so, the authors highlight the particular role educators play in the school-to-prison pipeline, focusing particularly on how dispositions toward black males influence educator practices. Recommendations and future directions are provided on how education preparation programs can play a critical role in the transformation of black male schooling.

Seed Dormancy, Seedling Establishment And Dynamics Of The Soil Seed Bank Of Stipa Bungeana (Poaceae) On The Loess Plateau Of Northwestern China, Xiao Wen Hu, Yan Pei Wu, Xing Yu Ding, Rui Zhang, Yan Rong Wang, Jerry M. Baskin, Carol C. Baskin

Biology Faculty Publications

Studying seed dormancy and its consequent effect can provide important information for vegetation restoration and management. The present study investigated seed dormancy, seedling emergence and seed survival in the soil seed bank of Stipa bungeana, a grass species used in restoration of degraded land on the Loess Plateau in northwest China. Dormancy of fresh seeds was determined by incubation of seeds over a range of temperatures in both light and dark. Seed germination was evaluated after mechanical removal of palea and lemma (hulls), chemical scarification and dry storage. Fresh and one-year-stored seeds were sown in the field, and seedling …

Graduate Research Conference Program, 2014, Emu Graduate School

Graduate Research Conference

No abstract provided.

Do Wetland Characteristics, Specifically Plant Communities, Surface Water, And Soils Play A Significant Role In Whooping Crane (Grus Americana) Site Selection?, Kristin Marie Bahleda

Master's Theses and Doctoral Dissertations

To examine the relationship of environmental conditions and their effect on Whooping crane (Grus americana) nest site selection; wetland soils, plant community structure and surface water quality were analyzed throughout nineteen established nest sites and twenty non-nesting wetland sites. Due to past fire management throughout the refuge, the effects of fire history were also investigated by comparing burned (n=17) and un-burned (n=22) areas.

A multi-dimensional scaling analysis did not detect significant differences in plant community structure between nest and non-nesting sites, but did find a significant difference with respect to time since last burn. Soil parameters were not …

Daily Eastern News: November 14, 2014, Eastern Illinois University

November

No abstract provided.

Graduate Research Conference Award Winners, 2014, Emu Graduate School

Graduate Research Conference

No abstract provided.

Modulation Of The Cardiac Calcium Release Channel By Homocysteine Thiolactone, Laura Jean Owen

Dissertations and Theses

Elevated levels in blood serum (≥10μmol/L) of the amino acid homocysteine is strongly correlated with the incidence of heart failure (HF). We present evidence that the cyclic thioester, homocysteine thiolactone (HTL), a metabolic product of homocysteine, irreversibly modifies proteins that regulate the contractile process in cardiac muscle. Two proteins found in the sarcoplasmic reticulum (SR), the Ca²⁺ pump (SERCA2), and the ryanodine receptor (RyR2), are responsible for controlling the cytosolic Ca²⁺ concentration and hence the contractile state of the heart. While both improper Ca²⁺ handling and elevated homocysteine levels have been considered bio-markers in HF, a direct …

November 14, 2014, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Engaging Faculty And Students Through Collection Assessment, Brian Gray, Daniela Solomon, Mark Eddy, Stephen Toombs

Researchers, Instructors, & Staff Scholarship

How do faculty and graduate students provide input for collection development? How well have librarians understood the research needs of recently tenured faculty or recent graduates? Four librarians from four different collection areas- the humanities, the social sciences, and 2 unique areas in engineering- all set out to see if evaluating the collection against recent publications by faculty and students can foster stronger engagement between them and the subject collectors in their areas.

2014 Northeastern Illinois University Fifth Annual Faculty Research Symposium - Program, Symposium Steering Committee

Faculty Research and Creative Activities Symposium 2010-2017

No abstract provided.

Connecting Undergraduate Science Education With The Needs Of Today's Graduates, Viviane Callier, Richard H. Singiser, Nathan L. Vanderford

Markey Cancer Center Faculty Publications

Undergraduate science programs are not providing graduates with the knowledgebase and skills they need to be successful on today’s job market. Curricular changes relevant to today’s marketplace and more opportunities for internships and work experience during students’ secondary education would facilitate a smoother transition to the working world and help employers find graduates that possess both the hard and soft skills needed in the workplace. In this article, we discuss these issues and offer solutions that would generate more marketplace-ready undergraduates.

Small Quantum Dots Conjugated To Nanobodies As Immunofluorescence Probes For Nanometric Microscopy, Yong Wang, En Cai, Tobias Rosenkranz, Pinghua Ge, Kai Wen Teng, Sung Jun Lim, Andrew M. Smith, Hee Jung Chung, Frederick Sachs, William N. Green, Philip Gottlieb, Paul R. Selvin

Physics Faculty Publications and Presentations

Immunofluorescence, a powerful technique to detect specific targets using fluorescently labeled antibodies, has been widely used in both scientific research and clinical diagnostics. The probes should be made with small antibodies and high brightness. We conjugated GFP binding protein (GBP) nanobodies, small single-chain antibodies from llamas, with new ∼7 nm quantum dots. These provide simple and versatile immunofluorescence nanoprobes with nanometer accuracy and resolution. Using the new probes we tracked the walking of individual kinesin motors and measured their 8 nm step sizes; we tracked Piezo1 channels, which are eukaryotic mechanosensitive channels; we also tracked AMPA receptors on living neurons. …

Generation And Characterization Of Nanoaerosols Using A Portable Scanning Mobility Particle Sizer And Electron Microscopy, Adam J. Marty

USF Tampa Graduate Theses and Dissertations

The purpose of this research is to demonstrate the ability to generate and characterize a nanometer sized aerosol using solutions, suspensions, and a bulk nanopowder, and to research the viability of using an acoustic dry aerosol generator/elutriator (ADAGE) to aerosolize a bulk nanopowder into a nanometer sized aerosol. The research compares the results from a portable scanning mobility particle sizer (SMPS) to the more traditional method of counting and sizing particles on a filter sample using scanning electron microscopy (SEM). Sodium chloride aerosol was used for the comparisons. The sputter coating thickness, a conductive coating necessary for SEM, was measured …

Müllerian Mimicry As A Result Of Codivergence Between Velvet Ants And Spider Wasps, Juanita Rodriguez, James P. Pitts, Carol D. Von Dohlen, Joseph S. Wilson

Biology Faculty Publications

Recent studies have delineated a large Nearctic Müllerian mimicry complex in Dasymutilla velvet ants. Psorthaspis spider wasps live in areas where this mimicry complex is found and are phenotypically similar to Dasymutilla. We tested the idea that Psorthaspis spider wasps are participating in the Dasymutilla mimicry complex and that they codiverged with Dasymutilla. We performed morphometric analyses and human perception tests, and tabulated distributional records to determine the fit of Psorthaspis to the Dasymutilla mimicry complex. We inferred a dated phylogeny using nuclear molecular markers (28S, elongation factor 1-alpha, long-wavelength rhodopsin and wingless) for Psorthaspis species and compared it to …

Collegian Magazine - Fall 2014

The Kenyon Collegian

No abstract provided.

Examination Of Possible Protective Effect Of Rhesus D Positive Blood Factor On Toxoplasma-Related Depressive Symptoms In Pregnancy, Lisa Lynn Parnell

USF Tampa Graduate Theses and Dissertations

Toxoplasma gondii infects approximately one third of the population worldwide. There is strong evidence that a relationship between T. gondii titer and depressive symptoms exists. There is also evidence suggesting a protective effect of RhD positive blood factor on toxoplasma-induced behavioral and personality changes. This protective effect may influence the relationship between T. gondii and prenatal depressive symptoms. The purpose of this secondary data analysis was to examine the possible protective effect of RhD positive blood factor on prenatal depressive symptoms in 56 pregnant women with T. gondii infection. The cross-sectional design was utilized to answer the question “Does positive …

Molecular Approaches To Chromatography Using Single Molecule Spectroscopy, Lydia Kisley

Faculty Scholarship

No abstract provided.

The Accidental Terrorists: Excludable Aliens Who Slip Across U.S. Borders, Susan M. Schreck

Georgia Journal of International & Comparative Law

No abstract provided.

China's Human Rights Record Since Tiananmen 1989 And The Recent Mixed Response Of The United States, Daniel C. Turack

Georgia Journal of International & Comparative Law

No abstract provided.

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for November 13-19, 2014. Vol. 98, No. 7.

Enantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]Octanes As Selective α4β2-Nachr Ligands, Oluseye K. Onajole, J. Brek Eaton, Ronald J. Lukas, Dani Brunner, Lucinda Thiede, Barbara J. Caldarone, Alan P. Kozikowski

Translational Neuroscience

We report the synthesis and characterization of a series of enantiopure 5-cyclopropane-bearing pyridyldiazabicyclo[3.3.0]octanes that display low nanomolar binding affinities and act as functional agonists at α4β2-nicotinic acetylcholine receptor (nAChR) subtype. Structure-activity relationship studies revealed that incorporation of a cyclopropane-containing side chain at the 5-position of the pyridine ring provides ligands with improved subtype selectivity for nAChR β2 subunit-containing nAChR subtypes (β2∗-nAChRs) over α4∗-nAChRs compared to the parent compound 4. Compound 15 exhibited subnanomolar binding affinity for α4β2-and α4β2∗-nAChRs with negligible interaction. Functional assays confirm selectivity for α4β2-nAChRs. Furthermore, using the SmartCube assay system, this ligand showed antidepressant, anxiolytic, and antipsychotic …