Digital Commons Network^™

Renowned Pharmacognosist To Present Waller Lecture, Erin Garrett

University of Mississippi News

A. Douglas Kinghorn returns to Ole Miss to discuss collaborative pharmaceutical research

Mda-9/Syntenin Regulates Differentiation And Angiogenesis Programs In Head And Neck Squamous Cell Carcinoma, Regina A. Oyesana, Shilpa Bhatia, Mitchell E. Menezes, Catherine I. Dumur, Karan P. Singh, Sejong Bae, Dean A. Troyer, Robert B. Wells, Edward R. Sauter, David Sidransky, Paul B. Fisher, Oliver J. Semmes, Santanu Dasgupta

School of Medical and Biological Sciences Faculty Publications and Presentations

Little is known about the molecular pathways regulating poor differentiation and invasion of head and neck squamous cell carcinoma (HNSCC). In the present study, we aimed to determine the role of MDA-9/Syntenin, a metastasis associated molecule in HNSCC tumorigenesis. Elevated MDA-9/Syntenin expression was evident in 67% (54/81) primary HNSCC tumors (p=0.001-0.002) and 69% (9/13) pre-neoplastic tissues (p=0.02-0.03). MDA-9/Syntenin overexpression was associated with the stage (p=0.001), grade (p=0.001) and lymph node metastasis (p=0.0001). Silencing of MDA-9/Syntenin in 3 poorly differentiated HNSCC cell lines induced squamous epithelial cell differentiation, disrupted angiogenesis and reduced tumor growth in vitro and in vivo. We confirmed …

A View From The Bridge, Beth Brosnan

UNH Today Archive

No abstract provided.

Manchester On The Move, Kim Wall

UNH Today Archive

No abstract provided.

Cellular Sleuth: Caelie Kern ’16 Researches Specific Protein’S Role In Cancer, Victoria Forrester Courtland

UNH Today Archive

No abstract provided.

The New Hampshire, Vol. 104 [105], No. 19 (Nov. 18, 2014), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 104, but it is the 105th volume in the series. This was corrected in pencil.

Hslic Journal Cancellations For 2015, Karen R. Mcelfresh, Jacob L. Nash

Publications

This document lists the journal subscriptions that will be cancelled by the Health Sciences Library & Informatics Center for 2015. Cost and use data for the last 4 years has been provided. All cancellations will take effect on January 1, 2015.

The Pathological Effects Of Ccr2+ Inflammatory Monocytes Are Amplified By An Ifnar1-Triggered Chemokine Feedback Loop In Highly Pathogenic Influenza Infection, Sue-Jane Lin, Ming Lo, Rei-Lin Kuo, Shin-Ru Shih, David M. Ojcius, Jean Lu, Chien-Kuo Lee, Hui-Chen Chen, Meei Yun Lin, Chuen-Miin Leu, Chia-Ni Lin, Ching-Hwa Tsai

All Dugoni School of Dentistry Faculty Articles

Background: Highly pathogenic influenza viruses cause high levels of morbidity, including excessive infiltration of leukocytes into the lungs, high viral loads and a cytokine storm. However, the details of how these pathological features unfold in severe influenza infections remain unclear. Accumulation of Gr1 + CD11b + myeloid cells has been observed in highly pathogenic influenza infections but it is not clear how and why they accumulate in the severely inflamed lung. In this study, we selected this cell population as a target to investigate the extreme inflammatory response during severe influenza infection.

Results: We established H1N1 IAV-infected mouse models using …

Extracellular Excystation And Development Of Cryptosporidium: Tracing The Fate Of Oocysts Within Pseudomonas Aquatic Biofilm Systems, Wan Koh, Andrew Thompson, Hann Edwards, Paul Monis, Peta L. Clode

Harold W. Manter Laboratory of Parasitology: Library Materials

Background: Aquatic biofilms often serve as environmental reservoirs for microorganisms and provide them with a nutrient-rich growth environment under harsh conditions. With regard to Cryptosporidium, biofilms can serve as environmental reservoirs for oocysts, but may also support the growth of additional Cryptosporidium stages.

Results: Here we used confocal laser scanning microscopy, scanning electron microscopy (SEM), and flow cytometry to identify and describe various Cryptosporidium developmental stages present within aquatic biofilm systems, and to directly compare these to stages produced in cell culture. We also show that Cryptosporidium has the ability to form a parasitophorous vacuole independently, in a host-free …

Bibliotherapy: An Approach To Treating Mental Illness In The Classroom, Erin M. Curry

Senior Honors Theses

The prevalence of adolescent mental illness has increased at an alarming rate over the past two decades. Due to a lack of accessible mental health care and the stigmatization of mental illness, parents of children with these disorders are often reluctant to seek help. These children often resort to negative self-coping methods among which include substance abuse, violence, and suicide. These negative self-coping methods have a harmful, lasting impact on the individual as well as the surrounding community.

Bibliotherapy, which harnesses the meditative power of books, can teach helpful coping skills to students with mental illness. When effectively utilized in …

Montana Kaimin, November 18, 2014, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

A Novel Role For Nf-Κb In Proximal T Cell Signaling, Crystina Bronk Watson

USF Tampa Graduate Theses and Dissertations

The interrogation of T cell signaling over the past fifty years has led to the discovery of amazingly intricate cascade networks and elaborate descriptions of individual proteins' domains and functions. A complex landscape has been rendered in which proteins relay messages from the extracellular ligation of the TCR by a cognate peptide loaded MHC via changes in sub-cellular location, phosphorylation, and binding affinities and partners to enact nuclear localization of three key transcription factors required for cellular effector function and proliferation: AP-1, NF-AT, and NF-κB. Dogma has favored activation of each of these transcription regulating elements to be a linear …

Native, Jeff Ploegstra

Faculty Work Comprehensive List

"Native as a noun and an adjective. How and where do you belong?"

Posting about what it means to be "native" from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.

http://inallthings.org/native/

Pcp-Ml: Protein Characterization Package For Machine Learning, Jesse Eickholt, Zheng Wang

Faculty Publications

Background: Machine Learning (ML) has a number of demonstrated applications in protein prediction tasks such as protein structure prediction. To speed further development of machine learning based tools and their release to the community, we have developed a package which characterizes several aspects of a protein commonly used for protein prediction tasks with machine learning.

Findings: A number of software libraries and modules exist for handling protein related data. The package we present in this work, PCP-ML, is unique in its small footprint and emphasis on machine learning. Its primary focus is on characterizing various aspects of a …

The Prospector, November 18, 2014, Utep Student Publications

The Prospector

Headline: No More: El Paso Continues to Stop Domestic Violence

Documentary Borders: Reality Or Illusion, Sabine Roux, Caroline Courbières

Proceedings from the Document Academy

The concept of border of document allows us to deploy the significant content of a document in several regimes of meaning. A document can be studied as a semiotic mediation according its communicational intention (intention to inform, intention to signify, intention to inform oneself, intention to interpretate). After studying those values of the document, the question is about whether a documentary border persists unchanged when regimes of meaning are updated. The slipping of documentary borders is examined through the content of the diverse works of Jocelyn Bonnerave. His doctoral thesis in anthropology documenting practices in performing arts influenced his theatrical …

Water Scarcity In The Jordan River Basin, Matthew Cook

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

The watershed of the Jordan River stretches over four countries – Jordan, Syria, Israel, and Lebanon – and includes the region of Palestine. With the land and its resources hotly contested by all parties involved, the dwindling supply of drinking and irrigation water from viable sources has led to scrambling exploitation, leaving the river and its connected lakes in an ever-worsening state of deterioration. Increased suspended solids, presence of toxin-producing cyanobacteria, and accelerated evapotranspiration have led to a slower, shallower, murkier, and lower health quality trickle taking the place of the once-revered River Jordan (Comair et al., “Watershed Delineation” …

The Bacterial Pathogen Yersinia Creates A Complex Structure On The Surface Of Macrophages, Wael Bahnan

Open Access Dissertations

During an infectious process, bacterial pathogens interact with host innate immune cells. These innate cells (primarily macrophages) play a major role in the antimicrobial defense and bacterial clearance. In this work, we identify the niche which Yersinia pseudotuberculosis creates during macrophage contact. We show that the pYV virulence plasmid is essential for the ability of the bacterium to create an acidified, partially enclosed, and durable niche along the macrophage surface. These compartments are uncoupled from the normal host cell endocytic trafficking pathway and are exposed to the extracellular medium. We present data which shows that the formation of the Yersinia …

Grand Valley Forum, Volume 039, Number 13, November 17, 2014, Grand Valley State University

2014-2015, Volume 39

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Lanthorn, Vol. 49, No. 26, November 17, 2014, Grand Valley State University

Volume 49, July 7, 2014 - June 1, 2015

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Creating Core Concepts In Animal Physiology, Patricia A. Halpin

Life Sciences Faculty Scholarship

No abstract provided.

Current, November 17, 2014, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.

The Statesman, V. 58, I. 13, Stony Brook University

Stony Brook Statesman-Sucolian

v. 58, i. 13

Columbia Chronicle (11/17/2014), Columbia College Chicago

Columbia Chronicle

Student newspaper from November 17, 2014 entitled The Columbia Chronicle. This issue is 40 pages and is listed as Volume 50, Number 12. Cover story: "Kim invites community to embrace Columbia" Editor-in-Chief: Tyler Eagle

Faculty Senate Executive Committee Agenda, November 17, 2014, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Follow-up from Faculty Form
• Review FS Presidency Visit to USU-Eastern
• Proposed FS president compensation policy
• Progress of PTR Working Committee
• EPC Items
• USU Student Association Report
• Retention and Student Success Report
• 405 Code Change Proposals from Provost’s office

Novel Theory Connects Mothers To Childhood Obesity: Evolution Is The Cause, Moms Are The Cure, Jim Bakken

Browse All News

No abstract provided.

Analysis Of Twitter Messages For Sentiment, Eric D. Brown

Masters Theses & Doctoral Dissertations

No abstract provided.

Cry1f Resistance In Fall Armyworm Spodoptera Frugiperda: Single Gene Versus Pyramided Bt Maize, Fangneng Huang, Jawwad A. Qureshi, Robert L. Meagher, Dominic D. Reisig, Graham P. Head, David A. Andow, Xinzi Ni, David Kerns, G. David Buntin, Ying Niu, Fei Yang, Vikash Dangal

Faculty Publications

Evolution of insect resistance to transgenic crops containing Bacillus thuringiensis (Bt) genes is a serious threat to the sustainability of this technology. However, field resistance related to the reduced efficacy of Bt maize has not been documented in any lepidopteran pest in the mainland U.S. after 18 years of intensive Bt maize planting. Here we report compelling evidence of field resistance in the fall armyworm, Spodoptera frugiperda (J.E. Smith), to Cry1F maize (TC 3507) in the southeastern region of the U.S. An F2 screen showed a surprisingly high (0.293) Cry1F resistance allele frequency in a population collected in 2011 from …

November 17, 2014 Armstrong Faculty Senate Agenda, Armstrong State University

Armstrong Faculty Senate: Armstrong Faculty Senate Agenda (Archived)

November 17, 2014 Armstrong Faculty Senate Agenda

Evolution Of Acyl-Substrate Recognition By A Family Of Acyl-Homoserine Lactone Synthases, Quin H. Christensen, Ryan M. Brecht, Dastagiri Dudekula, E. Peter Greenberg, Rajesh Nagarajan

Chemistry and Biochemistry Faculty Publications and Presentations

Members of the LuxI protein family catalyze synthesis of acyl-homoserine lactone (acyl-HSL) quorum sensing signals from S-adenosyl-L-methionine and an acyl thioester. Some LuxI family members prefer acyl-CoA, and others prefer acyl-acyl carrier protein (ACP) as the acyl-thioester substrate. We sought to understand the evolutionary history and mechanisms mediating this substrate preference. Our phylogenetic and motif analysis of the LuxI acyl-HSL synthase family indicates that the acyl-CoA-utilizing enzymes evolved from an acyl-ACP-utilizing ancestor. To further understand how acyl-ACPs and acyl-CoAs are recognized by acyl-HSL synthases we studied BmaI1, an octanoyl-ACP-dependent LuxI family member from Burkholderia mallei, and BjaI, an …