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2014

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Review On The Application Of Modified Iron Oxides As Heterogeneous Catalysts In Fenton Reaction, S.R. Pouran, Abdul Aziz Abdul Raman, Wan Mohd Ashri Wan Daud Jan 2014

Review On The Application Of Modified Iron Oxides As Heterogeneous Catalysts In Fenton Reaction, S.R. Pouran, Abdul Aziz Abdul Raman, Wan Mohd Ashri Wan Daud

Research Publications (2011 to 2015)

Heterogeneous Fenton reaction is an advanced oxidation process which has gained wide spread acceptance for higher removal efficiency of recalcitrant organic contaminants under wide range of pH compared to homogeneous reactions. Conventionally, iron oxides are used as heterogeneous catalysts for Fenton oxidation system because of their abundance, easy separation and lower cost. This paper reviews the substitution of iron in an iron oxide with other transition metals as a mean to improve the properties of the iron oxide towards higher performance for contaminant degradation. Several studies have reported enhanced performance resulted from this substitution based on two possible mechanisms. First …


Some Morphological, Anatomical Studies And Effects Of Hormones On In Vitro Culture Of Canav Alia Rosea (Sw) Dc, M.T. Rosna, M. Normadiha, A.R. Ummi Nur Ain, M. Sadegh Jan 2014

Some Morphological, Anatomical Studies And Effects Of Hormones On In Vitro Culture Of Canav Alia Rosea (Sw) Dc, M.T. Rosna, M. Normadiha, A.R. Ummi Nur Ain, M. Sadegh

Research Publications (2011 to 2015)

The current investigation encompasses some morphological, anatomical and tissue culture of Canavalia rosea (Sw) DC (leguminosea). which has the potential for soil stability especially on slopes.Morphological and anatomical studies comprised leaf venation, Scanning Electron Microscopy (SEM), histology analysis .and epidermal peeling. Results obtained showed that the leaftlorsiventral with bipinate venation and amphistomic withparacytic type stomata embedded below the epidermis. Anatomical studies of leaf and root were also done to determine the presence of specific cells such as cuticle; oil gland, structure of vascular system, shape and arrangement of the cells and other related structures. Regeneration from shoots was accomplished from …


Staphylobase: A Specialized Genomic Resource For The Staphylococcal Research Community, H. Heydari, N.V.R. Mutha, M.I. Mahmud, C.C. Siow, W.Y. Wee, G.J. Wong, A.H. Yazdi, M.Y. Ang, S.W. Choo Jan 2014

Staphylobase: A Specialized Genomic Resource For The Staphylococcal Research Community, H. Heydari, N.V.R. Mutha, M.I. Mahmud, C.C. Siow, W.Y. Wee, G.J. Wong, A.H. Yazdi, M.Y. Ang, S.W. Choo

Research Publications (2011 to 2015)

With the advent of high-throughput sequencing technologies, many staphylococcal genomes have been sequenced. Comparative analysis of these strains will provide better understanding of their biology, phylogeny, virulence and taxonomy, which may contribute to better management of diseases caused by staphylococcal pathogens. We developed StaphyloBase with the goal of having a one-stop genomic resource platform for the scientific community to access, retrieve, download, browse, search, visualize and analyse the staphylococcal genomic data and annotations. We anticipate this resource platform will facilitate the analysis of staphylococcal genomic data, particularly in comparative analyses. StaphyloBase currently has a collection of 754 032 protein-coding sequences …


Strain Improvement Of A Hypolipidemic Yellow Oyster Mushroom, Pleurotus Citrinopileatus By Mating Technique, A. Noorlidah, A.G. Rosnina, S. Vikineswary Jan 2014

Strain Improvement Of A Hypolipidemic Yellow Oyster Mushroom, Pleurotus Citrinopileatus By Mating Technique, A. Noorlidah, A.G. Rosnina, S. Vikineswary

Research Publications (2011 to 2015)

Oyster mushrooms (Pleurotus species) are cultivated widely and at present ranked second to the button mushroom in production. Pleurotus citrinopileatus (Yellow oyster mushroom) possessed antioxidants, antidiabetic and hypolipidemic properties' that can be a good source of therapeutics for the prevention and treatment of cardiovascular disease. The sporophores has an attractive shape and bright yellow colour, however, the texture is very fragile and has a strong aroma, which is not preferred by consumers, Hence, the present study was conducted with the objective of improving the texture, aroma and yield of P. citrinopileatus by interspecies mating using uninucleate monokaryotic cell of P. …


Subditine, A New Monoterpenoid Indole Alkaloid From Bark Of Nauclea Subdita (Korth.) Steud. Induces Apoptosis In Human Prostate Cancer Cells, S.Y. Liew, C.Y. Looi, M. Paydar, F.K. Cheah, K.H. Leong, W.F. Wong, Mohd Rais Mustafa, M. Litaudon, Khalijah Awang Jan 2014

Subditine, A New Monoterpenoid Indole Alkaloid From Bark Of Nauclea Subdita (Korth.) Steud. Induces Apoptosis In Human Prostate Cancer Cells, S.Y. Liew, C.Y. Looi, M. Paydar, F.K. Cheah, K.H. Leong, W.F. Wong, Mohd Rais Mustafa, M. Litaudon, Khalijah Awang

Research Publications (2011 to 2015)

In this study, a new apoptotic monoterpenoid indole alkaloid, subditine (1), and four known compounds were isolated from the bark of Nauclea subdita. Complete 1H- and 13C- NMR data of the new compound were reported. The structures of isolated compounds were elucidated with various spectroscopic methods such as 1D- and 2D- NMR, IR, UV and LCMS. All five compounds were screened for cytotoxic activities on LNCaP and PC-3 human prostate cancer cell-lines. Among the five compounds, the new alkaloid, subditine (1), demonstrated the most potent cell growth inhibition activity and selective against LNCaP with an IC50 of 12.24±0.19 µM and …


Synthetic Seeds Of Clitoria Ternatea L. For Mass Propagation And Conservation, M. Noraini, M.T. Rosna, R. Norlina, M. Sadegh Jan 2014

Synthetic Seeds Of Clitoria Ternatea L. For Mass Propagation And Conservation, M. Noraini, M.T. Rosna, R. Norlina, M. Sadegh

Research Publications (2011 to 2015)

Synthetic seeds of Clitoria ternatea-L, were successfully created from leaf explants within 3 weeks after germinated on Murashige and Skoog (MS) media. The seeds were initially washed with tap water and teepol, then the seeds were sterilised with 99% (v/v) sodium hypochlorite solution' for 1 minute and rinsed with distilled waterthree times. In a laminar flow cabinet, the seeds were dipped in 70% (v/v) ethanol for 1 minute and blotted with steriled tissue, 'The shoot tip explants were encapsulated with 3% alginate (w/v) which suplemented with various concentrations (0.5-2.5 mg/I) and combinations ofNAA, BAP and adenine. The optimum concentration for …


Temperature And Magnetic Field Driven Modifications In The I-V Features Of Gold-Dna-Gold Structure I-V, N.M. Khatir, Z. Abdul-Malek, S.M. Banihashemian Jan 2014

Temperature And Magnetic Field Driven Modifications In The I-V Features Of Gold-Dna-Gold Structure I-V, N.M. Khatir, Z. Abdul-Malek, S.M. Banihashemian

Research Publications (2011 to 2015)

The fabrication of Metal-DNA-Metal (MDM) structure-based high sensitivity sensors from DNA micro-and nanoarray strands is a key issue in their development. The tunable semiconducting response of DNA in the presence of external electromagnetic and thermal fields is a gift for molecular electronics. The impact of temperatures (25–55 °C) and magnetic fields (0–1200 mT) on the current-voltage (I-V) features of Au-DNA-Au (GDG) structures with an optimum gap of 10 μm is reported. The I-V characteristics acquired in the presence and absence of magnetic fields demonstrated the semiconducting diode nature of DNA in GDG structures with high temperature sensitivity. The saturation current …


The Role Of Psychiatrists And Tobacco Dependence Treatment, A.S. Amer Nordin, J.D. Sellman, S.J. Adamson Jan 2014

The Role Of Psychiatrists And Tobacco Dependence Treatment, A.S. Amer Nordin, J.D. Sellman, S.J. Adamson

Research Publications (2011 to 2015)

Objective: Global tobacco control efforts in both prevention and treatment have advanced to levels never imagined 20 years ago. This review examines the relationship between mental illness and tobacco use, with particular focus on the role of psychiatrists in the treatment of tobacco dependence. Methods: The literature search utilised MEDLINE, Embase and PsychINFO databases using the terms psychiatry, psychiatrist, smoking cessation, tobacco use disorder and tobacco dependence treatment. A manual search of all references from relevant scientific articles obtained was also conducted. Finally, further material sourced included all major guidelines for smoking cessation or tobacco dependence treatment from the United …


Tissue-Mimicking Gel Phantoms For Thermal Therapy Studies, A. Dabbagh, B.J.J. Abdullah, C. Ramasindarum, N.H. Abu Kasim Jan 2014

Tissue-Mimicking Gel Phantoms For Thermal Therapy Studies, A. Dabbagh, B.J.J. Abdullah, C. Ramasindarum, N.H. Abu Kasim

Research Publications (2011 to 2015)

Tissue-mimicking phantoms that are currently available for routine biomedical applications may not be suitable for high-temperature experiments or calibration of thermal modalities. Therefore, design and fabrication of customized thermal phantoms with tailored properties are necessary for thermal therapy studies. A multitude of thermal phantoms have been developed in liquid, solid, and gel forms to simulate biological tissues in thermal therapy experiments. This article is an attempt to outline the various materials and techniques used to prepare thermal phantoms in the gel state. The relevant thermal, electrical, acoustic, and optical properties of these phantoms are presented in detail and the benefits …


Up-Regulation Of Hsa-Mir-608, In Response To Bci-Xl Silencing, Increases Cell Death In A549 And Sk-Lul Human Lung Adenocarcinoma Cells, N. Othman, N.H. Nagoor Jan 2014

Up-Regulation Of Hsa-Mir-608, In Response To Bci-Xl Silencing, Increases Cell Death In A549 And Sk-Lul Human Lung Adenocarcinoma Cells, N. Othman, N.H. Nagoor

Research Publications (2011 to 2015)

No abstract provided.


Variations In Motility And Biofilm Formation Of Salmonella Enterica Serovar Typhi Gut Pathogens, Kalaivani Kalai Chelvam, L.C. Chai, Kwai Lin Thong Jan 2014

Variations In Motility And Biofilm Formation Of Salmonella Enterica Serovar Typhi Gut Pathogens, Kalaivani Kalai Chelvam, L.C. Chai, Kwai Lin Thong

Research Publications (2011 to 2015)

Background: Salmonella enterica serovar Typhi (S. Typhi) exhibits unique characteristics as an intracellular human pathogen. It causes both acute and chronic infection with various disease manifestations in the human host only. The principal factors underlying the unique lifestyle of motility and biofilm forming ability of S. Typhi remain largely unknown. The main objective of this study was to explore and investigate the motility and biofilm forming behaviour among S. Typhi strains of diverse background. Results: Swim and swarm motility tests were performed with 0.25% and 0.5% agar concentration, respectively; while biofilm formation was determined by growing the bacterial cultures for …


Venom-Gland Transcriptome And Venom Proteome Of The Malaysian King Cobra (Ophiophsgus Hannuh), C.H. Tan, K.Y. Tanz, S.M. Sim, N.H. Tan Jan 2014

Venom-Gland Transcriptome And Venom Proteome Of The Malaysian King Cobra (Ophiophsgus Hannuh), C.H. Tan, K.Y. Tanz, S.M. Sim, N.H. Tan

Research Publications (2011 to 2015)

No abstract provided.


Establishing Referance Intervals For Haematological Parameters, Soluble Serum Transferrin Receptor And Serum Transferrin In A Tertiary Hospital In Malaysia, S. Hemalatha, K. Thatcheiany, S. Pavai Jan 2014

Establishing Referance Intervals For Haematological Parameters, Soluble Serum Transferrin Receptor And Serum Transferrin In A Tertiary Hospital In Malaysia, S. Hemalatha, K. Thatcheiany, S. Pavai

Research Publications (2011 to 2015)

Clinical laboratory testing is an integral part of diagnosis, treatment and prognosis that ensures quality and effective healthcare. Factors like genetics, dietary intake, gender, age, level of physical activity, altitude above sea level etc. can alter biochemical and haematological parameters in a population Variation can also occur based on the instrument or methodology being used. Thus it is pivotal for laboratories to establish their own reference intervals specific for their population. In our laboratory we have been interpreting CBC results based on the reference value established for the western population. In the context above, we decided to establish our own …


Defining The Physiochemical, Biological And Habitat Requirements For The Upper Extant Of Oncorhynchus Mykiss Distribution, Emily Powers Jan 2014

Defining The Physiochemical, Biological And Habitat Requirements For The Upper Extant Of Oncorhynchus Mykiss Distribution, Emily Powers

Journal of Earth and Life Science

The distribution of rainbow trout is strongly influenced by their habitat. As climatic conditions change, the distribution of rainbow trout populations will change along with them. The objective of this study was to identify the particular habitat parameters that rainbow trout select for in this lotic system and to specifically assess how this relates to the upper extant of their distribution. By assessing the distribution of the upper extant specifically, future research may be conducted to better assess climatic changes on a small and/or large scale basis. A 9,000 m section of the Clearwater River was used as the study …


The Effects Of Angling Pressure On Northern Pike Size Structure, Ryan Carrow Jan 2014

The Effects Of Angling Pressure On Northern Pike Size Structure, Ryan Carrow

Journal of Earth and Life Science

A number of conditions within a lake system can affect northern pike (Esox lucius) size structure. Of these conditions, the amount of angling pressure may have the biggest effect on the size structure of northern pike in Minnesota lake systems. In this study, five private and five public lakes were chosen near Bemidji, Minnesota. Each lake was fished for twenty angling hours using live northern hog suckers (Hypentelium nigricans) or golden shiners (Notemigonus crysoleucas). Total length (mm) and weight (kg) were measured for each northern pike caught. The number of fish houses that were …


Cave Rock Surface Temperature Evaluation Using Non-Contact Measurement Methods, Hana Středová, Tomáš Středa, Miroslav Vysoudil Jan 2014

Cave Rock Surface Temperature Evaluation Using Non-Contact Measurement Methods, Hana Středová, Tomáš Středa, Miroslav Vysoudil

KIP Articles

The aim of this study was to evaluate the rock surface temperature (RST) regime in Kateřinská Cave in the Moravian Karst (Czech Republic, South Moravia) using nondestructive infrared methods. Air temperature monitoring was also included to quantify the dominant factors affecting the RST. Measurements were taken during the period covering January, 2010 to March, 2012. HOBO air temperature sensors with data loggers were placed in front of the cave entrance, in the entrance corridor and on selected sites in the cave interior. An infrared (IR) thermometer was used to measure the surface temperature of the solid rock. The RST in …


Litter Deposition And Nitrogen Return In Rotationally Stocked Smooth Bromegrass Pastures, John A. Guretzky, Walter H. Schacht, Ana B. Wingeyer, Terry J. Klopfenstein, Andrea K. Watson Jan 2014

Litter Deposition And Nitrogen Return In Rotationally Stocked Smooth Bromegrass Pastures, John A. Guretzky, Walter H. Schacht, Ana B. Wingeyer, Terry J. Klopfenstein, Andrea K. Watson

Department of Animal Science: Faculty Publications

Understanding how management systems impact nutrient cycling is important to pasture sustainability. From 2010 to 2011, we investigated how supplementation of beef cattle (Bos taurus) with corn (Zea mays L.) dried distillers grains plus solubles (DDGS) on unfertilized, rotationally stocked smooth bromegrass (Bromus inermis Leyss.) pasture (SUPP) affected the litter pool, residual herbage mass, litter deposition, and litter quality relative to unsupplemented beef cattle rotationally stocked on unfertilized control (CONT) and N-fertilized (FERT) smooth bromegrass pastures. As hypothesized based on management for greater herbage mass and animal demand during the grazing season, litter deposition was 48% …


Effects Of Beef Production System On Animal Performance And Carcass Characteristics, C. L. Maxwell, C. R. Lopez, B. K. Wilson, B. T. Johnson, B. C. Bernhard, C. F. O'Neill, D. L. Vanoverbeke, G. G. Mafi, D. L. Step, C. J. Richards Jan 2014

Effects Of Beef Production System On Animal Performance And Carcass Characteristics, C. L. Maxwell, C. R. Lopez, B. K. Wilson, B. T. Johnson, B. C. Bernhard, C. F. O'Neill, D. L. Vanoverbeke, G. G. Mafi, D. L. Step, C. J. Richards

Department of Animal Science: Faculty Publications

The objective of this study was to evaluate conventional (CONV) and natural (NAT) beef production systems from annual pasture through finishing through grazing. Beef steers (n = 180, initial BW = 250 ± 19 kg) were assigned randomly to 2 treatments in the pasture phase. Steers were implanted with 40 mg of trenbolone acetate (TBA), 8 mg estradiol, and 29 mg tylosin tartrate (CONV), or received no implant (NAT). Steers on the 2 treatments grazed wheat or cereal rye for 109 d. Conventional steers had an 18.5% improvement in ADG (1.22 vs. 1.03 kg/d, P < 0.01) and a heavier final BW (385 vs. 366 kg, P < 0.01) compared with NAT steers. Following the pasture phase, steers (n = 160 steers, 5 steers/pen, 8 pens/treatment) were assigned to a 2 × 2 factorial in the feedlot phase. Production system (NAT vs. CONV) was maintained from the pasture phase, and the second factor was 7 vs. 12% low-quality roughage (DM basis, LOW vs. HIGH). During finishing, CONV steers were given 120 mg of TBA and 24 mg estradiol at processing, fed monensin and tylosin, and fed zilpaterol hydrochloride for the last 20 d of the experiment. There were no program × roughage level interactions (P > 0.07). The CONV steers ate …


System And Method For Analyzing Properties Of Meat Using Multispectral Imaging, Jeyamkondan Subbiah, Chris Richard Calkins, Ashok Kumor Samal, Govindarajan Konda Naganathan Jan 2014

System And Method For Analyzing Properties Of Meat Using Multispectral Imaging, Jeyamkondan Subbiah, Chris Richard Calkins, Ashok Kumor Samal, Govindarajan Konda Naganathan

Department of Animal Science: Faculty Publications

A system and method for obtaining multispectral images of fresh meat at predetermined wavelength bands at a first time, subjecting the images to analysis in an image analysis system comprising a computer programmed to perform such analysis, and outputting a forecast of meat tenderness at a later point in time. Predetermined key wavelength bands are precorrelated with a high degree of prediction of meat tenderness and/or other properties of meat and are used in the multispectral system and method. A system and method for determining the key wavelengths is also disclosed. The multispectral imaging system and method is suitable for …


Western Immunoblotting In Avian Shell Gland Sample Immunoblotting Methods1, K.K. Hansen, R.J. Kittok, Gautam Sarath, Mary M. Beck Jan 2014

Western Immunoblotting In Avian Shell Gland Sample Immunoblotting Methods1, K.K. Hansen, R.J. Kittok, Gautam Sarath, Mary M. Beck

Department of Animal Science: Faculty Publications

Avian shell gland tissue was subjected to Western blot analysis using anti-human estrogen receptor- α antibody H222. Initial attempts to obtain consistent, high-quality blots were unsuccessful because, as it turned out, excessive lipid in tissue preparations interfered with protein separation. Incremental additions of acetone eventually proved to be the critical step in solubilizing lipids and allowing consistent separation of bands on gels. A detailed description of the methodology is presented.


Life Beneath The Surface Of The Central Texan Balcones Escarpment: Genus Anillinus Casey, 1918 (Coleoptera, Carabidae, Bembidiini): New Species, A Key To The Texas Species, And Notes About Their Way Of Life And Evolution, Igor M. Sokolov Jan 2014

Life Beneath The Surface Of The Central Texan Balcones Escarpment: Genus Anillinus Casey, 1918 (Coleoptera, Carabidae, Bembidiini): New Species, A Key To The Texas Species, And Notes About Their Way Of Life And Evolution, Igor M. Sokolov

KIP Articles

No abstract provided.


The Role Of Spiritual Faith Healers In Reducing Or Reinforcing The Hiv Stigma: A Qualitative Study, Nkeke Lesolang Jan 2014

The Role Of Spiritual Faith Healers In Reducing Or Reinforcing The Hiv Stigma: A Qualitative Study, Nkeke Lesolang

Papers from the International Association for Cross-Cultural Psychology Conferences

The role of spiritual faith healers in managing various conditions of ill-health has been studied and debated. The aim of this study was to explore spiritual faith healers’ understanding and conceptualisation of HIV/AIDS stigma and the role they play in reducing or reinforcing HIV/AIDS stigma in their communities. A qualitative approach, and in particular, the grounded theory methodology was used. The application of this methodology included personal interviews with eight practising spiritual faith healers in Limpopo Province (South Africa), while additional information was gleaned from the literature review. The researcher focused on the participants’ conceptualisation of HIV stigma, from the …


The African Conception Of Death: A Cultural Implication, Lesiba Baloyi, Molebogeng Makobe-Rabothata Jan 2014

The African Conception Of Death: A Cultural Implication, Lesiba Baloyi, Molebogeng Makobe-Rabothata

Papers from the International Association for Cross-Cultural Psychology Conferences

From an African perspective death is a natural transition from the visible to the invisible spiritual ontology where the spirit, the essence of the person, is not destroyed but moves to live in the spirit ancestors’ realm dead. It signifies an inextricable spiritual connection between the visible and invisible worlds. This chapter focuses on how traditional Africans conceive and deal with the bereavement process. We adopt the African worldview and philosophy as our framework. We dispute the often held view in mainstream psychology that behavior, in this case the concept of death and the bereavement processes have universal applicability, articulation, …


High Prevalence Of Dissociative Amnesia And Related Disorders In Immigrated People, Angelica Staniloiu, Hans J. Markowitsch Jan 2014

High Prevalence Of Dissociative Amnesia And Related Disorders In Immigrated People, Angelica Staniloiu, Hans J. Markowitsch

Papers from the International Association for Cross-Cultural Psychology Conferences

Across various cultures, dissociative amnesic disorders have been shown to be triggered by psychological stress or trauma. In immigrant populations, stressful experiences can arise during pre-emigration, migration or post-migration phase. Preliminary data suggest that stresses related to various phases of migration and acculturation could trigger dissociative amnesic disorders via a dysregulation of hormonal stress responses. These findings are highly relevant in the era of increased globalization and call for culturally sensitive approaches, in order to accurately diagnose and optimally manage these conditions in the future.


The Hang-Up With Hamburg: How Center For Food Safety V. Hamburg Will Alter The Food Industry, Joella Roland Jan 2014

The Hang-Up With Hamburg: How Center For Food Safety V. Hamburg Will Alter The Food Industry, Joella Roland

Journal of Business & Technology Law

No abstract provided.


Evaluation Of Three Herbicide Resistance Genes For Use In Genetic Transformations And For Potential Crop Protection In Algae Production, Andrew J. Bruggeman, Daniel Kuehler, Donald P. Weeks Jan 2014

Evaluation Of Three Herbicide Resistance Genes For Use In Genetic Transformations And For Potential Crop Protection In Algae Production, Andrew J. Bruggeman, Daniel Kuehler, Donald P. Weeks

Department of Biochemistry: Faculty Publications

Genes conferring resistance to the herbicides glyphosate, oxyfluorfen and norflurazon were developed and tested for use as dominant selectable markers in genetic transformation of Chlamydomonas reinhardtii and as potential tools for the protection of commercial-scale algal production facilities against contamination by organisms sensitive to these broad-spectrum herbicides. A synthetic glyphosate acetyltransferase (GAT) gene, when fitted with a strong Chlamydomonas promoter, conferred a 2.79-fold increase in tolerance to the EPSPS inhibitor, glyphosate, in transgenic cells compared with progenitor WT cells. A mutant Chlamydomonas protoporphyrinogen oxidase (protox, PPO) gene previously shown to produce an enzyme insensitive to PPO-inhibiting herbicides, when genetically engineered, …


The Islamic Influence In (Pre-)Colonial And Early America: A Historico-Legal Snapshot, Nadia B. Ahmad Jan 2014

The Islamic Influence In (Pre-)Colonial And Early America: A Historico-Legal Snapshot, Nadia B. Ahmad

Faculty Scholarship

No abstract provided.


A Model Of The Effect Of Uncertainty On The C Elegans L2/L2d Decision, Leon Avery Jan 2014

A Model Of The Effect Of Uncertainty On The C Elegans L2/L2d Decision, Leon Avery

Physiology and Biophysics Publications and Presentations

Abstract

At the end of the first larval stage, the C elegans larva chooses between two developmental pathways, an L2 committed to reproductive development and an L2d, which has the option of undergoing reproductive development or entering the dauer diapause. I develop a quantitative model of this choice using mathematical tools developed for pricing financial options. The model predicts that the optimal decision must take into account not only the expected potential for reproductive growth, but also the uncertainty in that expected potential. Because the L2d has more flexibility than the L2, it is favored in unpredictable environments. I estimate …


A Digital Environmental Approach: Four Technologies That Will Disrupt Social Work Practice, Lauri Goldkind Jan 2014

A Digital Environmental Approach: Four Technologies That Will Disrupt Social Work Practice, Lauri Goldkind

Social Service Faculty Publications

and by technology. Social work offers a panoramic perspective on individuals and issues, insisting on the importance of the ecology of interaction between person and environment. Given this historic strength, social workers cannot ignore the explosive growth and pervasive impact of technology or fail to recognize its role in shaping culture. Beyond its capacity to enhance whatwe offer to our clients, technology is a prompt, a demand to reimagine our core values in the context of a changing social space and to develop amechanics of practice that is amenable to rapid evolution. With this commentary we hope to initiate dialogue: …


Cardiac Extracellular Proteome Profiling And Membrane Topology Analysis Using Glycoproteomics, Yuan Tian, Tejaswi Koganti, Zhihao Yao, Presley Cannon, Punit Shah, Laura Pietrovito, Alessandra Modesti, Paul Aiyetan, Kristine Deleon-Pennell, Yonggang Ma, Ganesh V. Halade, Chindo Hicks, Hui Zhang, Merry L. Lindsey Jan 2014

Cardiac Extracellular Proteome Profiling And Membrane Topology Analysis Using Glycoproteomics, Yuan Tian, Tejaswi Koganti, Zhihao Yao, Presley Cannon, Punit Shah, Laura Pietrovito, Alessandra Modesti, Paul Aiyetan, Kristine Deleon-Pennell, Yonggang Ma, Ganesh V. Halade, Chindo Hicks, Hui Zhang, Merry L. Lindsey

Internal Medicine Faculty Publications

Purpose: Extracellular proteins are easily accessible, which presents a subproteome of molecular targets that have high diagnostic and therapeutic potential. Efforts have been made to catalog the cardiac extracellular matridome and analyze the topology of identified proteins for the design of therapeutic targets. Although many bioinformatics tools have been developed to predict protein topology, topology has been experimentally validated for only a very small portion of membrane proteins. The aim of this study was to use a glycoproteomics and MS approach to identify glycoproteins in the extracellular matridome of the infarcted left ventricle (LV) and provide experimental evidence for topological …