Digital Commons Network^™

An Exploration Of The Ozone Dimer Potential Energy Surface, L. M. Azofra, I. Alkorta, Steve Scheiner

Chemistry and Biochemistry Faculty Publications

The (O3)2 dimer potential energy surface is thoroughly explored at the ab initio CCSD(T) computational level. Five minima are characterized with binding energies between 0.35 and 2.24 kcal/mol. The most stable may be characterized as slipped parallel, with the two O3 monomers situated in parallel planes. Partitioning of the interaction energy points to dispersion and exchange as the prime contributors to the stability, with varying contributions from electrostatic energy, which is repulsive in one case. Atoms in Molecules analysis of the wavefunction presents specific O⋯O bonding interactions, whose number is related to the overall stability of each dimer. All internal …

Amphibian Species Of The World [Book Review], Kevin Mcdonough

Book Reviews

No abstract provided.

Princeton Guide To Evolution [Book Review], Kevin Mcdonough

Book Reviews

No abstract provided.

Intrinsic Delocalization During The Decay Of Excitons In Polymeric Solar Cells, Thomas George, W. Chen, D. Jiang, R. Chen, S. Li

Chemistry & Biochemistry Faculty Works

In bulk heterojunction polymer solar cells, external photoexcitation results in localized excitons in the polymer chain. After hot exciton formation and subsequent relaxation, the dipole moment drives the electron to partially transfer to extended orbitals from the original localized ones, leading to self-delocalization. Based on the dynamic fluorescence spectra, the delocalization of excitons is revealed to be an intrinsic property dominated by exciton decay, acting as a bridge for the exciton to diffuse in the polymeric solar cell. The modification of the dipole moment enhances the efficiency of polymer solar cells.

Cross Talk Between The Cell Wall Integrity And Cyclic Amp/Protein Kinase A Pathways In Cryptococcus Neoformans, Maureen J. Donlin, Rajendra Upadhya, Kimberly J. Gerik, Woei Lam, Laura G. Vanarendonk, Charles A. Specht, Neil K. Sharma, Jennifer K. Lodge

Open Access Publications

No abstract provided.

Single Nucleotide Variants In Transcription Factors Associate More Tightly With Phenotype Than With Gene Expression, Priya Sudarsanam, Barak A. Cohen

Open Access Publications

No abstract provided.

Complete Genome Sequence Of Anabaena Variabilis Atcc 29413, Teresa Thiel, Brenda Pratte, Jinshun Zhong, Lynne Goodwin, Alex Copeland, Susan Lucas, Cliff Han, Sam Pitluck, Miriam Land, Nikos Kyrpides, Tanja Woyke

Biology Department Faculty Works

Anabaena variabilis ATCC 29413 is a filamentous, heterocyst-forming cyanobacterium that has served as a model organism, with an extensive literature extending over 40 years. The strain has three distinct nitrogenases that function under different environmental conditions and is capable of photoautotrophic growth in the light and true heterotrophic growth in the dark using fructose as both carbon and energy source. While this strain was first isolated in 1964 in Mississippi and named Anabaena flos-aquae MSU A-37, it clusters phylogenetically with cyanobacteria of the genus Nostoc. The strain is a moderate thermophile, growing well at approximately 40° C. Here we provide …

Spectrum, 2014, Northwestern College

Spectrum literary magazine

Literary journal

Building Stones From A Quarry In Northern Jerusalem Probably Used In The Temple Mount: 5 Years After The Discovery, Amnon Rosenfeld, Tsevi Minster, Shimon Ilani, Howard R. Feldman

Lander College for Women - The Anna Ruth and Mark Hasten School Publications and Research

During the summer of 2009 a quarry was unearthed in the Ramat Shlomo neighborhood, northern Jerusalem, during land development for the construction of a new school. The excavated area of the quarry was about one acre and is indicative of substantial mining activity in the Turonian (Bina Formation) white limestone beds (known locally as “meleke” = king) from which blocks up to 8 meters in length and 1-2 meters in width were excavated. The dimensions of the large blocks are very rare in known domestic ancient quarries, and thus were considered to be relocated for use in the construction of …

3(D) View Of India’S Patent Law: Social Justice Aspiration Meets Property Rights In Novartis V. Union Of India & Others, 13 J. Marshall Rev. Intell. Prop. L. 719 (2014), Saby Ghoshray

UIC Review of Intellectual Property Law

Not many constitutional decisions from developing countries find themselves at the center of global debate like the Indian Supreme Court’s Novartis decision invalidating the Gleevec patent. The patent was invalidated under amended Section 3(d) of the Indian Patents Act, which was amended to address some of the concerns of imbalance between the maximalist and minimalist cultures in the pharmaceutical context. Section 3(d) of the Indian Patent Act introduced a new threshold of patent eligibility for pharmaceutical innovation that requires applicants to demonstrate enhanced efficacy of their products. The objective of this Article is to get beyond the reactionary reviews of …

Urinformed Fall 2014, Urinformed

URInformed: The URI Employees' Newsletter

No abstract provided.

Quantitative Analysis Of Woodpecker Habitat Using High-Resolution Airborne Lidar Estimates Of Forest Structure And Composition, James E. Garabedian, Robert Mcgaughey, Stephen E. Reutebuch, Bernard R. Parresol, John C. Kilgo, Christopher E. Moorman, M. Nils Peterson

United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications

Light detection and ranging (LiDAR) technology has the potential to radically alter theway researchers and managers collect data onwildlife–habitat relationships. To date, the technology has fostered several novel approaches to characterizing avian habitat, but has been limited by the lack of detailed LiDAR-habitat attributes relevant to species across a continuum of spatial grain sizes and habitat requirements. We demonstrate a novel three-step approach for using LiDAR data to evaluate habitat based on multiple habitat attributes and accounting for their influence at multiple grain sizes using federally endangered red-cockaded woodpecker (RCW; Picoides borealis) foraging habitat data fromthe Savannah River Site (SRS) …

The Multidimensionality Of Hermeneutic Phenomenology: From Philology Through Science And Technology To Theology, Babette Babich

Research Resources

Studies of hermeneutics have historically invoked and even enumerated dimensions and hermeneutic phenomenology is inherently multidimensional. In part this is due to the essential connection between hermeneutics and philology, which one cannot overlook. But it is also the legacy of Wilhelm Dilthey in particular. Hence Joseph J. Kockelman’s 2003 *Ideas for a Hermeneutic Phenomenology of the Natural Sciences* invokes “The Importance of Methodical Hermeneutics.” With this description, echoing the contributions of his friend and long-time colleague, Thomas Seebohm, Kockelmans relates Dilthey to Boeckh and thus to the classic tradition of hermeneutics including but also well in advance of Gadamer. Hence …

The Universality Of Hermeneutics In Joseph Kockelmans’S Version Of Hermeneutic Phenomenology, Dimitri Ginev

Research Resources

In an autobiographical sketch, Joseph Kockelmans (2008) reflects on his Denkweg in a manner that allows him to delineate the profile of his version of hermeneutic phenomenology. Based essentially on this sketch, I should like in what follows to bring into focus three principal moments of his “journey into phenomenological philosophy” that allude to his idea of the universality of interpretation in all culturally specified modes of being-in-the-world. I will call these moments respectively (a) the phenomenological reformulation of the Greek episteme; (b) the integration of the ontological difference in the theory of scientific truth; and (c) the historicity of …

Consciousness, Quantum Physics, And Hermeneutical Phenomenology, Patrick Aidan Heelan S.J.

Research Resources

Two hundred years ago Friedrich Schleiermacher modified Kant’s notion of anthropology—‘hermeneutically,’ as he said — so as to make it inclusive of the tribes that Captain Cook found in the South Sea Islands. This paper honors the late Joseph J. Kockelmans for making a similar hermeneutic move to update Kant’s notion of natural science so as to make it inclusive of the phenomenological lifeworld (For ‘lifeworld,’ see Husserl’s The Crisis of European Sciences and Transcendental Philosophy, 1954, 121–148, and the ‘lifeworld’ theme throughout the Crisis. ) syntheses of classical, relativity, and quantum physics. The new synthesis is in …

The Universality Of Hermeneutics In Joseph Kockelmans’ Version Of Hermeneutic Phenomenology, Dimitri Ginev

Research Resources

There is in Professor Kockelmans’s works from the 1950s a gradual transition from Nikolai Hartmann’s theory of the ontological modalities and categories (addressed in its capacity to serve as a prerequisite for reconstructing the ontological assumptions of basic scientifi c theories) to a kind of hermeneutic ontology. This transition is especially palpable in his reading of Hartmann’s “Philosophy of Nature.” In Hartmann’s categorial metaphysics of knowledge Dasein and Sosein (as ways of being) are subordinated to the modes and spheres of being. The transition was by no means accomplished via a direct borrowing of Heidegger’s concept of Dasein . It …

Honors Day, 2014, Murray State University

Honors Day Programs

Honors Day Programs, Murray State University. (Digitization and metadata processed by Madison Erwin.)

Conservation Of Energy: An Analytical Tool For Student Accounts Of Carbon-Transforming Processes, J. Dauer, H. Miller, C. W. Anderson

School of Natural Resources: Faculty Publications

No abstract provided.

Dnah5 Is Associated With Total Lung Capacity In Chronic Obstructive Pulmonary Disease, Jin Hwa Lee, Merry-Lynn N Mcdonald, Michael H. Cho, Emily S. Wan, Peter J. Castaldi, Gary M. Hunninghake, Nathaniel Marchetti, David A. Lynch, James D. Crapo, David A. Lomas, Harvey O. Coxson, Per S. Bakke, Edwin K. Silverman, Craig P. Hersh, The Copdgene And Eclipse Investigators

Journal Articles: Pulmonary & Critical Care Med

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by expiratory flow limitation, causing air trapping and lung hyperinflation. Hyperinflation leads to reduced exercise tolerance and poor quality of life in COPD patients. Total lung capacity (TLC) is an indicator of hyperinflation particularly in subjects with moderate-to-severe airflow obstruction. The aim of our study was to identify genetic variants associated with TLC in COPD.

METHODS: We performed genome-wide association studies (GWASs) in white subjects from three cohorts: the COPDGene Study; the Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE); and GenKOLS (Bergen, Norway). All subjects were current or ex-smokers …

Fisheries Research Report No. 233 - Status Of The Blue Swimmer Crab Fishery In Shark Bay, Western Australia Fishery Assessment Document, David Harris, Danielle Johnston, Errol Sporer, Mervi Kangas, Felipe Nieves, Nick Caputi

Fisheries Research Reports

The Shark Bay Crab Fishery on the central coast of Western Australia has developed rapidly in the last 10 years to become Australia’s highest producing blue swimmer crab fishery, with peak landings in 2010 of 828t valued at over AU$6 million. The resource is harvested commercially by the Shark Bay crab trap and Shark Bay prawn trawl fisheries, with negligible amounts retained by the Shark Bay scallop fishery. There are currently five 300-trap licences and 28 trawl (18 prawn and 10 scallop) licences authorized to take blue swimmer crabs in Shark Bay.

Application Of Loop-Mediated Isothermal Amplification (Lamp) In Microbiological Water Quality Analysis, Nduta F. Mwangi

All Master’s Theses

Water is life thus access to safe drinking water is essential to health and a basic human right. Kenya is considered a water scarce country whose water sources are becoming more contaminated through changes in land use and poor solid waste management. This has in turn affected the quantity and quality of portable water available. There are nearly 1.7 billion cases of waterborne diarrheal disease every year with over 760 000 deaths of children under five years. Traditional methods of identification of waterborne pathogens are less specific, sensitive, timeconsuming and laborious, so there is a need for the development of …

Comparing The Long Term Use Of H2 Antagonists (H2ras) And Proton Pump Inhibitors (Ppis) And The Incidence Of Colitis, Reiner Kremer

Physician Assistant Scholarly Project Posters

• Commonly used medications for GERD may affect the colonic mucosa

• H2 antagonists (H2RAs) ranitidine, cimetidine famotidine reduce acid secretion by 60 to 70%.

• Proton pump inhibitors (PPIs) omeprazole, pantoprazole, lansoprazole, esomeprazole and rabeprazole reduce acid secretion by inhibiting the H+ (proton) secreting pump, reducing hydrochloric acid by 80 to 95%.

• Diarrhea is one of the most commonly reported adverse events.

• H2RAs and PPIs have the physiological and functional potential to interfere with gastrointestinal physiology by altering intestinal pH.

• Microcytic colitis causing chronic diarrhea and colonic inflammation is a significant complication risk after the > 4-8 …

Genome-Wide Annotation Of Chemosensory And Glutamate-Gated Receptors, And Related Genes In Glossina Morsitans Morsitans Tsetse Fly, George Fredrick Obiero Opondo

All PhD Dissertations

Tsetse flies are the sole vectors of trypanosomes that cause nagana and sleeping sickness in animals and humans respectively in tropical Africa. Tsetse are unique: both sexes adults are exclusive blood-feeders, females are mated young and give birth to a single mature larva in sheltered habitats per pregnancy. Tsetse use chemoreception to detect and respond to chemical stimuli, helping them to locate hosts, mates, larviposition and resting sites. The detection is facilitated by chemoreceptors expressed on sensory neurons to cause specific responses. Specific molecular factors that mediate these responses are poorly understood in tsetse flies. This study aimed to identify …

A Study Of The Experience Of Female African-American Seventh Graders In A Science, Technology, Engineering, And Math (Stem) Afterschool Program, Beverley Fiona Hinds

Master's Theses and Doctoral Dissertations

The purpose of this qualitative study was to determine what inspires or leads seventh-grade African-American girls toward an interest in STEM, to characterize and describe the context of an out-of-school STEM learning environment, explore the impact on the seventh- grade African-American girls who participated in the program as it relates to individual STEM identity, and identify personal and academic experiences of seventh-grade African- American girls that contribute to the discouragement or pursuit of science and math-related academic pathways and careers. Notable findings in this study included the following: 1. Participants were interested in STEM and able to identify both external …

Effect Of Invasive Phragmites Australis And Its Control On Microbial Community Composition In A Freshwater Wetland, Jennifer K. Kirk

Master's Theses and Doctoral Dissertations

Wetlands support great species diversity and perform important ecosystem services like carbon and nutrient cycling, largely facilitated by microorganisms. Invasive plants, like Phragmites australis, reduce biodiversity and alter ecosystem services. I hypothesized that changes in soil bacterial communities would occur after Phragmites invasion and restoration efforts employing herbicide to remove Phragmites would further disrupt communities. This was tested in freshwater wetlands using terminal restriction fragment length polymorphism analysis of PCR amplified eubacterial DNA from soils dominated by Typha and Phragmites vegetation preceding and following herbicide application. Soil bacterial communities differed by vegetation type and indicated both seasonal and inter-annual effects. …

Uncovering Identities Through Performance Poetry, Angela Vanhook

Master's Theses and Doctoral Dissertations

Research in the area of performance poetry is still relatively new to the field of communication. Using Hecht’s Communication Theory of Identity, this study explores performance poetry as a communicative tool for identity management. By observing the performances of five poets from six seasons of HBO’s Def Poetry Jam, a thematic analysis of the communication practices that occurred during the performances was used to code the processes of identity management. Additionally, this study explores how validation of enacted identity occurs between the poets and their audiences. Findings suggest that performance poetry could effectively be utilized as a tool in identity …

Constructing Tailored Isoprenoid Products By Structure-Guided Modification Of Geranylgeranyl Reductase, Yan Kung, Ryan P. Mcandrew, Xinkai Xie, Charlie C. Liu, Jose H. Pereira, Paul D. Adams, Jay D. Keasling

Chemistry Faculty Research and Scholarship

The archaeal enzyme geranylgeranyl reductase (GGR) catalyzes hydrogenation of carbon-carbon double bonds to produce the saturated alkyl chains of the organism's unusual isoprenoid-derived cell membrane. Enzymatic reduction of isoprenoid double bonds is of considerable interest both to natural products researchers and to synthetic biologists interested in the microbial production of isoprenoid drug or biofuel molecules. Here we present crystal structures of GGR from Sulfolobus acidocaldarius, including the structure of GGR bound to geranylgeranyl pyrophosphate (GGPP). The structures are presented alongside activity data that depict the sequential reduction of GGPP to H(6)GGPP via the intermediates H(2)GGPP and H(4)GGPP. We then modified …

Southeast Ohio Winter/Spring 2014, E.W. Scripps School Of Journalism

Southeast Ohio Magazine

Table of contents:

History
Discover quilt trails, a drive-in theater and more ... 4

Around the Region
Find a distillery, parade, new hobby and an artist on the move ...6

Vineyard in the Valley
Enjoy river views, award-winning wines and elegant dining at Moyer Winery ... 8

Under the Shell
See why Southeast Ohioans are crazy for turtles ... 10

It’s a Small World
Danny Yahini creates tiny homes full of character ... 12

Shoot for Flavor
Area hunters offer their tips for cooking wild game ... 14

The Sweetest Sound
The Big Scioty Dulcimer Club strings together tranquil music …

Microrna-194 (Mir-194) Regulates Romk Channel Activity By Targeting Intersectin 1, Dao-Hong Lin, Peng Yue, Chengbiao Zhang, Wen-Hui Wang

NYMC Faculty Publications

The aim of the study is to explore the role of miR-194 in mediating the effect of high-K (HK) intake on ROMK channel. Northern blot analysis showed that miR-194 was expressed in kidney and that HK intake increased while low-K intake decreased the expression of miR-194. Real-time PCR analysis further demonstrated that HK intake increased the miR-194 expression in the cortical collecting duct. HK intake decreased the expression of intersectin 1 (ITSN1) which enhanced With-No-Lysine Kinase (WNK)-induced endocytosis of ROMK. Expression of miR-194 mimic decreased luciferase reporter gene activity in HEK293 T cells transfected with ITSN-1-3'UTR containing the complementary seed …

Physiological And Molecular Responses In Adult And Larvae Anopheles Gambiae S.S. To Murraya Koenigii Phytochemicals, Clarence Maikuri Mangera

All PhD Dissertations

Continuous application of synthetic insecticides causes development of resistance in vector species, biological magnification of toxic substances through the food chain and adverse effects on environmental quality and non-target organisms including human health. Naturally occurring plant compounds and their derivatives are, therefore, of increasing interest for the development of new compounds against the malaria vector. In this study, adulticidal and larvicidal activity of essential oil and crude extracts isolated from the leaves of Murraya koenigii against mosquito vectors will be investigated. Essential oil will be isolated from the leaves of M koenigii using hydro-distillation method. Different compounds will be identified …