Digital Commons Network^™

Morehead State University - Vet Village, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Stewart, Jesse, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Purification Of A Serine Protease And Evidence For A Protein C Activator From The Saliva Of The Tick, Ixodes Scapularis, Sivakamasundari Pichu, José M.C. Ribeiro, Thomas N. Mather, Ivo M.B. Francischetti

Plant Sciences and Entomology Faculty Publications

The saliva of ticks is critical to their survival as parasites and hematophagous animals. In this study, we have purified an enzyme with trypsin-like activity from the saliva of the tick vector of Lyme Disease, Ixodes scapularis. This enzyme, named as IXOSP (I. scapularis salivary serine protease), is a 29.9 kDa molecule with N-terminus FPxMVxLRIKxR. A BLAST search identified IXOSP as a secreted serine protease (AAY66740) with a conserved catalytic triad His, Asp, and Ser. In vitro studies demonstrated that IXOSP cleaves chromogenic substrates with arginine in the P₁ position, by a mechanism inhibited by PMSF or …

Restoring Sacred Waters: A Guide To Protecting Tribal Non-Consumptive Water Uses In The Colorado River Basin, Julie Nania, Julia Guarino, University Of Colorado Boulder. Getches-Wilkinson Center For Natural Resources, Energy, And The Environment

Books, Reports, and Studies

105 p. : color illustrations ; 28 cm

Introduction -- Gathering information and starting the process -- Indian federal reserved water rights -- Using Indian federal reserved water rights for instream flows -- Negotiating for non-consumptive uses in settlement agreements -- Protecting non-consumptive uses in tribal water codes -- Other legal tools -- Irrigating for instream flows and traditional plants -- Summary and key points

Fractional Generalizations Of Filtering Problems And Their Associated Fractional Zakai Equation, Sabir Umarov, Fred Daum, Kenric Nelson

Mathematics Faculty Publications

In this paper we discuss fractional generalizations of the filtering problem. The ”fractional” nature comes from time-changed state or observation processes, basic ingredients of the filtering problem. The mathematical feature of the fractional filtering problem emerges as the Riemann-Liouville or Caputo-Djrbashian fractional derivative in the associated Zakai equation. We discuss fractional generalizations of the nonlinear filtering problem whose state and observation processes are driven by time-changed Brownian motion or/and Lévy process.

Images From The 2014 Clemson's Biological Science's Annual Student Symposium, Jonn Foulk

Clemson's Biological Science's Annual Student Symposium

No abstract provided.

Just Keep Grazing: Parrotfish Grazing And Dietary Selectivity In The Florida Keys, B. Quirk-Royal, S. Hoffman, M. Childress, K. Smith

Focus on Creative Inquiry

Parrotfish have indirect positive effects on corals by grazing on macroalgae that competes for substrate space with corals. Parrotfish can also have a negative impact on corals by feeding on live coral. Feeding preferences are correlated to jaw morphology in parrotfishes. This study examined the feeding selectivity for two genera of parrotfish (Scarus and Sparisoma) in the Florida Keys to determine the impacts they have on coral reefs. On 14 reefs, fish censuses, behavioral surveys and substrate composition analysis were preformed to calculate selectivity indices for the various substrate types. The indices showed that parrotfish do exhibit selective feeding. Scarus …

Impact Of Mobile Devices On Clinical Laboratory Data, C. Chaudhary, J. Albertson, C. Andrews, A. Anglin, L. Bulloch, T. Dennison, J. Elder, C. Holliday, C. Lyron, E. Smith, R. Smith, V. Gallicchio

Focus on Creative Inquiry

Recent advancements in mobile wireless devices (smart phones and tablets) have given these products the potential to drastically alter the practice of healthcare. The project described determined how these devices would assist in improving diagnosis, treatment, and therapeutic outcomes in the delivery of healthcare. Also, it seeks to determine if the healthcare community feels these devices will make healthcare more cost effective and affordable. To cover multiple aspects of healthcare, several groups have been targeted: clinical laboratory; emergency, dental, rehabilitation, and surgical medicine; hospital administration; diagnostic imaging technology; public health; and veterinary medicine. This presentation will focus on our current …

Modeling Population Structure And Adaptation In A Hawaiian Stream Goby: Sicyopterus Stimpsoni, E. O'Conner, M. Burgess, M. Childress, K. Moody

Focus on Creative Inquiry

Due to the environmental problem of climate change, it has been forecasted that the Hawaiian islands can expect increased drought and increased rainfall variability. This could cause a change in stream flow and threaten the amphidromous waterfall climbing gobies, Sicyopterus stimpsoni. To study the impact of these projected changes, we used spatially-explicit, individual-based population models with four levels drought and three levels of rainfall variability for three islands with different topographies (Hawai'i, O'ahu and Kaua'i) and looked at the effect on the goby population dynamics after 10 years. Our results showed that total abundance was impacted by drought, variability, and …

Light-Responsive Facade Prototype, B. Smentek, A. Javed, D. Lee

Focus on Creative Inquiry

Research into improving building energy performance has the potential to create new and innovative architectural products. Through developing "green" architectural technologies aimed at increasing energy efficiency architects and engineers must overcome the financial architectural and engineering challenges of their implementation. A prototype facade design was designed to respond to sunlight intensity as part of a study on similar facade schemes.

Royal Jelly-Mediated Prolongevity In Caenorhabditis Elegans Is Modulated By The Interplays Of Daf-16, Sir-2.1, Hcf-1 And 14-3-3 Proteins, L. Cook, L. Grasso, Y. Dong, X. Wang

Focus on Creative Inquiry

Recent studies suggested that royal jelly and its substances may have anti-aging properties and can be utilized as nutraceuticals. However, the molecular mechanisms underlying its beneficial effects are far from clearly elucidated. Our genetic analyses suggested that the effect of royal jelly (RJ) and enzyme-treated royal jelly (eRJ) on lifespan and healthspan in Caenorhabditis elegansis modulated by the functional interplays of DAF-16, SIR-2.1, HCF-1 and 14-3-3 proteins. Previous studies have reported that DAF-16/FOXO, SIR-2.1/SIRT1, 14-3-3, and HCF-1 are important prolongevity determinants and have extensive interplays in worms and mammals. Considering the conservation of these prolongevity determinants in diverse species, this …

In Vivo Femoral Strains In Swimming Turtles: Influence Of Locomotor Medium On Limb Bone Loading, J. Sutton, R. Blob, V. Young

Focus on Creative Inquiry

The transition from aquatic to terrestrial habitats was an event in vertebrate evolution that preceded a sudden radiation of species. Subsequently some vertebrate lineages have returned to their ancestral aquatic habitats. It is known that vertebrate bone structure can vary depending on habitat. The evolutionary explanation for this is attributable to the fact that loads on the skeleton varies depending on the environment organisms inhabit. Terrestrial vertebrates would be expected to experience greater loads on their bones versus aquatic vertebrates due to body support demands, but there are no experimental data to test this hypothesis or quantify the difference. We …

The Influence Of Rearing Environment On Life History And Morphological Traits Of Sailfin Molly Fish (P. Latipinna), G. Davidson, C. Crawford, M. Voytko, K. Hogan, M. Ptacek

Focus on Creative Inquiry

Life history traits such as time to and size at maturity are influenced by both genetic and environmental factors. One such environmental factor may be the social environment in which a juvenile is reared. This study examined the life history traits of sailfin mollies (Poecilia latipinna) that were reared in varying social environments: in isolation, in groups with an adult male present, and in groups without an adult male present. Since females prefer larger males, we anticipated that males reared in the presence of an adult male should delay maturation and therefore mature at larger sizes in order to better …

Cu And The Cdc, C. Howard, K. Remillard, K. Toth, R. Hardy, J. Painter, D. Limbaugh, T. Mcnealy, C. Wells

Focus on Creative Inquiry

Legionella is a gram-negative genus of bacteria that is the cause of Legionnaires disease. Currently, 50 species and 70 serogroups of Legionella have been identified. The Center for Disease Control (CDC) in Atlanta maintains a bank of identified and unidentified Legionella samples. The availability of sequencing technologies has increased since many samples were collected allowing for identification of many previously unidentifiable isolates. We received 68 unidentified samples from the CDC. A sequence based typing scheme was used for characterization. Genomic DNA was extracted from samples and polymerase chain reactionwas performed on the 16S and mip genes. These samples were then …

Compounds From Fermented Noni Exudates (Fne) Selectively Kill Human Cancer Cells, R. Borucki, A. Blumer, H. Huggins, Y. Wei, A. Tietje, X. Yang

Focus on Creative Inquiry

Our recent studies involving fermented noni exudates (fNE) made from noni (Morinda citrifolia) have shown promising anti-cancer activities. Using an in vitro cell culture system, this study examines dozens of compounds isolated from fNE in order to identify specific compounds preferentially toxic to tumor cells. The compounds at concentrations of 20, 5, or 2 μg/ml were added to NL-20 non-tumor lung cells or A549 lung carcinoma cells and incubated for 48 hours. The cytotoxicity of the compounds on the cells was measured using the MTS cell proliferation assay. Several compounds were found selectively effective in killing more A549 tumor cells …

Nir Camera For Early Detection Of Diabetic Ulcers, M. Portilla Rodriguez, M. Hoelzen, D. Athavale, V. Reukov, A. Shaporev

Focus on Creative Inquiry

The purpose of this Creative Inquiry is to test whether near-infrared (NIR) imaging devices can detect areas of skin at risk for ulceration in diabetic patients. Venous blood accumulation, or high levels of deoxygenated blood within a tissue, can indicate poor blood circulation and increased risk of ulceration. Here we propose to detect venous blood in tissues using differences in optical spectra of oxygenated vs. deoxygenated blood in NIR region. We previously designed and built a prototype scanner with three integrated NIR light sources that is being tested at MUSC. Our current work is focused on testing of improved NIR …

Macro-Afm Model, M. Hoelzen, D. Athavale, M. Portilla Rodriguez, V. Reukov, A. Shaporev

Focus on Creative Inquiry

An Atomic Force Microscope (AFM) is an important tool in modern nanoscience, capable of producing surface maps at resolutions below 1 nanometer, which is impossible for other methods. Despite AFM's often use, it is often difficult for students to understand their work because all measurement processes take place at micro- and nano-scale. The goal of this project is to create a macro scale model, which will serve as an educational tool to introduce the principles behind AFM to undergraduate and high school students. Currently, a fully automatic microprocessor-controlled surface scanning block has been built and successfully tested with a scan …

Literary And Cinematic Perspectives On Gender Studies, M. Husain, E. Winburn, K. Lovett, H. Haire, C. Dunnigan, G. Tissera, D. Martin

Focus on Creative Inquiry

This project focuses on gender studies including women, men, and sexual diversity studies. Students explore gender and sexuality in the fields of literature and cinema related to cultural, social, and economic issues in Latin America and Spain. The analysis includes a diverse selection of topics: gender and science, gender and sexuality, gender and minority ethnicities, feminism and diversity, transgender identities, transgender healthcare, lesbian and gay figures and trends, and intersex and culture.

The Ecology Of A New Invasion By Bellamya Japonica In The Savannah Basin, B. Broome, T. Woollen, J. Logan, L. Frees, R. Helstern, S. Fishburne, J. Hains

Focus on Creative Inquiry

The first known infestation of Bellamya japonica in the Savannah River Basin was discovered in 2006. Investigations of this population led to questions regarding their distribution and behavior. We have completed experiments on behavior and concluded that there exists a significant negative phototactic but no detectable geotactic response. In addition, a study of their dispersal using mark-recapture methods concluded that, while this technique was useful to follow the life history of individual snails, they did not meet the method assumptions and therefore this method could not produce a reliable population estimate. Studies of fecundity have shown a seasonal trend with …

71st Annual Pepperdine Bible Lectureship -- Enter The Water, Come To The Table (2014), Mike Cope

Pepperdine Bible Lectures: Programs

Program booklet for the 71st Annual Pepperdine Bible Lectures, held at Pepperdine University in Malibu, California, April 29 - May 2, 2014. The Pepperdine Bible Lectures is an annual event hosted by Pepperdine University featuring a wide variety of lectures and classes on topics and themes in the Bible and Christianity.

Mike Cope, Lectureship Director

Rick Gibson, Tami Williamson, and Joella Michael, Lectures Team

2014 Scholarly Productivity Report, Missouri University Of Science And Technology

Civil, Architectural and Environmental Engineering Scholarly Productivity Reports

No abstract provided.

Agrobest: An Efficient Agrobacterium-Mediated Transient Expression Method For Versatile Gene Function Analyses In Arabidopsis Seedlings, Hang-Yi Wu, Kun-Hsiang Liu, Yi-Chieh Wang, Jing-Fen Wu, Wan-Ling Chiu, Chao-Ying Chen, Shu-Hsing Wu, Jen Sheen, Erh-Min Lai

Study of Biological Complexity Publications

Background

Transient gene expression via Agrobacterium-mediated DNA transfer offers a simple and fast method to analyze transgene functions. Although Arabidopsis is the most-studied model plant with powerful genetic and genomic resources, achieving highly efficient and consistent transient expression for gene function analysis in Arabidopsis remains challenging.

Results

We developed a highly efficient and robust Agrobacterium-mediated transient expression system, named AGROBEST (Agrobacterium-mediated enhanced seedling transformation), which achieves versatile analysis of diverse gene functions in intact Arabidopsis seedlings. Using β-glucuronidase (GUS) as a reporter for Agrobacterium-mediated transformation assay, we show that the use of a specific disarmed …

Virginia Commonwealth University Commencement Program [2014], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Genesis And Pathogenesis Of The 1918 Pandemic H1n1 Influenza A Virus, Michael Worobey, Guan-Zhu Han, Andrew Rambaut

Uniformed Services University of the Health Sciences

The source, timing, and geographical origin of the 1918–1920 pandemic influenza A virus have remained tenaciously obscure for nearly a century, as have the reasons for its unusual severity among young adults. Here, we reconstruct the origins of the pandemic virus and the classic swine influenza and (postpandemic) seasonal H1N1 lineages using a host-specific molecular clock approach that is demonstrably more accurate than previous methods. Our results suggest that the 1918 pandemic virus originated shortly before 1918 when a human H1 virus, which we infer emerged before ∼1907, acquired avian N1 neuraminidase and internal protein genes. We find that the …

Research At The University Of Nebraska-Lincoln: 2013-2014 Report

Office of Research and Economic Development: Publications

The 2013-2014 UNL Research Report, published by the University of Nebraska-Lincoln Office of Research and Economic Development, highlights some of the diverse research, scholarship and creative activity at the heart of UNL’s research enterprise during the fiscal year July 1, 2013, through June 30, 2014. A companion website includes more photos, videos and additional resources.

Eight Reasons Why Attorneys Representing Parents In Child Protection Proceedings Should Use An Intimate Partner Violence Screening Protocol, Nancy Ver Steegh

William Mitchell Law Review

No abstract provided.

Hatch-Waxman And Medical Devices, Brian P. Wallenfelt

William Mitchell Law Review

No abstract provided.

2014-2015 Eiu School Of Continuing Education Annual Report, Eastern Illinois University

Annual Reports

The 2014-2015 Eastern Illinois University School of Continuing Education Annual Report.

Uab Magazine - Fall 2014, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.

Lifelines Winter 2014, Southern Adventist University

Lifelines - Biology Department Newsletter

The Winter 2014 issue of Lifelines contains articles on a dinosaur dig in Wyoming, student missions to Lebanon, an alumni feature, undergraduate research, and a pictorial directory of 2014 biology and allied health graduates.